1980 B.A., Biochemistry
University of California at Berkeley, Berkeley, CA
1988 Ph.D., Molecular Biophysics & Biochemistry
Yale University, New Haven, CT
Laboratory of Dr. Joan A. Steitz
1988-1992, Postdoctoral Fellow,
Harvard University, Cambridge, MA
Department of Biochemistry and Molecular Biology
Laboratory of Dr. Douglas A. Melton
1992-1999, Assistant Professor of Biology
Department of Molecular Biology, Cell Biology & Biochemistry
Brown University, Providence, RI
1999-2005, Associate Professor of Biology
Department of Molecular Biology, Cell Biology & Biochemistry
Brown University, Providence, RI
2005-present, Professor of Biology
Department of Molecular Biology, Cell Biology & Biochemistry
Brown University, Providence, RI
Cabral SE, Otis JP, Mowry KL. "Multivalent interactions with RNA drive recruitment and dynamics in biomolecular condensates in Xenopus oocytes." iScience, vol. 25, no. 8, 2022, pp. 104811. |
Neil CR, Jeschonek SP, Cabral SE, O'Connell LC, Powrie EA, Otis JP, Wood TR, Mowry KL. "L-bodies are RNA–protein condensates driving RNA localization in Xenopus oocytes." Molecular Biology of the Cell, vol. 32, no. 22, 2021, pp. ar37. |
O'Connell, Liam C., Mowry, Kimberly L. "Regulation of spatially restricted gene expression: linking RNA localization and phase separation." Biochemical Society Transactions, vol. 49, no. 6, 2021, pp. 2591-2600. |
Cabral SE, Mowry KL. "Organizing the oocyte: RNA localization meets phase separation." Current Topics in Developmental Biology, vol. 140, 2020, pp. 87-118. |
Mowry KL. "Using the Xenopus Oocyte Toolbox." Cold Spring Harbor Protocols, vol. 2020, no. 4, 2020, pp. 095844. |
Neil CR, Mowry K. "Fluorescence In Situ Hybridization of Cryosectioned Xenopus Oocytes." Cold Spring Harbor Protocols, vol. 2018, no. 5, 2018. |
Ciocanel, Maria-Veronica, Sandstede, Bjorn, Jeschonek, Samantha P., Mowry, Kimberly L. "Modeling Microtubule-Based Transport and Anchoring of mRNA." SIAM Journal on Applied Dynamical Systems, vol. 17, no. 4, 2018, pp. 2855-2881. |
Ciocanel, Maria-Veronica, Sandstede, Bjorn, Jeschonek, Samantha P., Mowry, Kimberly L. "Modeling Microtubule-Based Transport and Anchoring of mRNA." SIAM Journal on Applied Dynamical Systems, vol. 17, no. 4, 2018, pp. 2855-2881. |
Ciocanel, Maria-Veronica, Sandstede, Bjorn, Jeschonek, Samantha P., Mowry, Kimberly L. "Modeling Microtubule-Based Transport and Anchoring of mRNA." SIAM Journal on Applied Dynamical Systems, vol. 17, no. 4, 2018, pp. 2855-2881. |
Jeschonek SP, Mowry KL. "Whole-Mount Immunofluorescence for Visualizing Endogenous Protein and Injected RNA in Xenopus Oocytes." Cold Spring Harbor Protocols, vol. 2018, no. 10, 2018. |
Ciocanel MV, Kreiling JA, Gagnon JA, Mowry KL, Sandstede B. "Analysis of Active Transport by Fluorescence Recovery after Photobleaching." Biophysical Journal, vol. 112, no. 8, 2017, pp. 1714-1725. |
Powrie EA, Ciocanel V, Kreiling JA, Gagnon JA, Sandstede B, Mowry KL. "Using in vivo imaging to measure RNA mobility in Xenopus laevis oocytes." Methods, vol. 98, 2015, pp. 60-65. |
Gagnon JA, Kreiling JA, Powrie EA, Wood TR, Mowry KL. "Directional transport is mediated by a Dynein-dependent step in an RNA localization pathway." PLoS biology, vol. 11, no. 4, 2013, pp. e1001551. |
Pratt CA, Mowry KL. "Taking a cellular road-trip: mRNA transport and anchoring." Current opinion in cell biology, vol. 25, no. 1, 2013, pp. 99-106. |
Medioni C, Mowry K, Besse F. "Principles and roles of mRNA localization in animal development." Development, vol. 139, no. 18, 2012, pp. 3263-76. |
Gagnon JA, Mowry KL. "Molecular motors: directing traffic during RNA localization." Critical Reviews in Biochemistry and Molecular Biology, vol. 46, no. 3, 2011, pp. 229-39. |
Gagnon JA, Mowry KL. "Visualization of mRNA localization in Xenopus oocytes." Methods in Molecular Biology, vol. 714, 2011, pp. 71-82. |
Pratt CA, Mowry KL. "Preparation of a highly active cell-free translation system from immature Xenopus laevis oocytes." Methods, vol. 51, no. 1, 2010, pp. 101-5. |
Gagnon JA, Mowry KL. "Visualizing RNA localization in Xenopus oocytes." Journal of visualized experiments : JoVE, no. 35, 2010. |
Gagnon JA, Mowry KL. "VISIONS: the art of science." Mol. Reprod. Dev., vol. 76, no. 12, 2009, pp. 1115. |
Messitt TJ, Gagnon JA, Kreiling JA, Pratt CA, Yoon YJ, Mowry KL. "Multiple kinesin motors coordinate cytoplasmic RNA transport on a subpopulation of microtubules in Xenopus oocytes." Developmental Cell, vol. 15, no. 3, 2008, pp. 426-36. |
Lewis RA, Gagnon JA, Mowry KL. "PTB/hnRNP I is required for RNP remodeling during RNA localization in Xenopus oocytes." Molecular and Cellular Biology, vol. 28, no. 2, 2008, pp. 678-86. |
Mowry, Kimberly L., Gagnon, James A., Kreiling, Jill A., Messitt, Timothy J., Pratt, Catherine A., Yoon, Young J. "RNA transport in the oocyte cytoplasm: How to get there from here." Developmental Biology, vol. 319, no. 2, 2008, pp. 464. |
Lewis RA, Mowry KL. "Ribonucleoprotein remodeling during RNA localization." Differentiation; research in biological diversity, vol. 75, no. 6, 2007, pp. 507-18. |
King ML, Messitt TJ, Mowry KL. "Putting RNAs in the right place at the right time: RNA localization in the frog oocyte." Biology of the cell / under the auspices of the European Cell Biology Organization, vol. 97, no. 1, 2005, pp. 19-33. |
Lewis, Raymond A., Kress, Tracy L., Cote, Colette A., Gautreau, Denise, Rokop, Megan E., Mowry, Kimberly L. "Conserved and clustered RNA recognition sequences are a critical feature of signals directing RNA localization in Xenopus oocytes." Mechanisms of development, vol. 121, no. 1, 2004, pp. 101-109. |
Chang P, Torres J, Lewis RA, Mowry KL, Houliston E, King ML. "Localization of RNAs to the mitochondrial cloud in Xenopus oocytes through entrapment and association with endoplasmic reticulum." Molecular biology of the cell, vol. 15, no. 10, 2004, pp. 4669-81. |
Kress TL, Yoon YJ, Mowry KL. "Nuclear RNP complex assembly initiates cytoplasmic RNA localization." The Journal of cell biology, vol. 165, no. 2, 2004, pp. 203-11. |
Yoon YJ, Mowry KL. "Xenopus Staufen is a component of a ribonucleoprotein complex containing Vg1 RNA and kinesin." Development, vol. 131, no. 13, 2004, pp. 3035-45. |
Volodina N, Denegre JM, Mowry KL. "Apparent mitochondrial asymmetry in Xenopus eggs." Developmental dynamics : an official publication of the American Association of Anatomists, vol. 226, no. 4, 2003, pp. 654-62. |
Xie J, Lee JA, Kress TL, Mowry KL, Black DL. "Protein kinase A phosphorylation modulates transport of the polypyrimidine tract-binding protein." Proceedings of the National Academy of Sciences, vol. 100, no. 15, 2003, pp. 8776-81. |
Bubunenko M, Kress TL, Vempati UD, Mowry KL, King ML. "A consensus RNA signal that directs germ layer determinants to the vegetal cortex of Xenopus oocytes." Developmental Biology, vol. 248, no. 1, 2002, pp. 82-92. |
Valles JM Jr, Wasserman SR, Schweidenback C, Edwardson J, Denegre JM, Mowry KL. "Processes that occur before second cleavage determine third cleavage orientation in Xenopus." Experimental Cell Research, vol. 274, no. 1, 2002, pp. 112-8. |
Cote CA, Gautreau D, Denegre JM, Kress TL, Terry NA, Mowry KL. "A Xenopus protein related to hnRNP I has a role in cytoplasmic RNA localization." Molecular Cell, vol. 4, no. 3, 1999, pp. 431-7. |
Mowry KL, Cote CA. "RNA sorting in Xenopus oocytes and embryos." The FASEB Journal, vol. 13, no. 3, 1999, pp. 435-45. |
Denegre JM, Valles JM Jr, Lin K, Jordan WB, Mowry KL. "Cleavage planes in frog eggs are altered by strong magnetic fields." Proceedings of the National Academy of Sciences, vol. 95, no. 25, 1998, pp. 14729-32. |
Denegre JM, Ludwig ER, Mowry KL. "Localized maternal proteins in Xenopus revealed by subtractive immunization." Developmental Biology, vol. 192, no. 2, 1997, pp. 446-54. |
Valles JM Jr, Lin K, Denegre JM, Mowry KL. "Stable magnetic field gradient levitation of Xenopus laevis: toward low-gravity simulation." Biophysical Journal, vol. 73, no. 2, 1997, pp. 1130-3. |
Gautreau D, Cote CA, Mowry KL. "Two copies of a subelement from the Vg1 RNA localization sequence are sufficient to direct vegetal localization in Xenopus oocytes." Development, vol. 124, no. 24, 1997, pp. 5013-20. |
Mowry KL. "Complex formation between stage-specific oocyte factors and a Xenopus mRNA localization element." Proceedings of the National Academy of Sciences, vol. 93, no. 25, 1996, pp. 14608-13. |
Mowry KL, Melton DA. "Vegetal messenger RNA localization directed by a 340-nt RNA sequence element in Xenopus oocytes." Science, vol. 255, no. 5047, 1992, pp. 991-4. |
Mowry KL, Oh R, Steitz JA. "Each of the conserved sequence elements flanking the cleavage site of mammalian histone pre-mRNAs has a distinct role in the 3'-end processing reaction." Molecular and Cellular Biology, vol. 9, no. 7, 1989, pp. 3105-8. |
Mowry KL, Steitz JA. "snRNP mediators of 3' end processing: functional fossils?." Trends in biochemical sciences, vol. 13, no. 11, 1988, pp. 447-51. |
Mowry KL, Steitz JA. "Both conserved signals on mammalian histone pre-mRNAs associate with small nuclear ribonucleoproteins during 3' end formation in vitro." Molecular and Cellular Biology, vol. 7, no. 5, 1987, pp. 1663-72. |
Mowry KL, Steitz JA. "Identification of the human U7 snRNP as one of several factors involved in the 3' end maturation of histone premessenger RNA's." Science, vol. 238, no. 4834, 1987, pp. 1682-7. |
Wang EA, Mowry KL, Clegg DO, Koshland DE Jr. "Tandem duplication and multiple functions of a receptor gene in bacterial chemotaxis." Journal of Biological Chemistry, vol. 257, no. 9, 1982, pp. 4673-6. |
Year | Degree | Institution |
---|---|---|
1988 | PhD | Yale University |
1980 | BA | University of California, Berkeley |
Helen Hay Whitney Fellow (1989-1992)
Advanced Postdoctoral-Postresidency Fellow, American Cancer Society (1992)
Salomon Faculty Research Award (1997-1998)
Vartan Gregorian Assistant Professor (1997-1999)
Elizabeth Leduc Award for Excellence in Teaching in the Life Sciences, Brown University (2007)
Robin Chemers Neustein Professor of Biomedicine (2009-present)
Dean’s Award for Excellence in Graduate and Postdoctoral Teaching and Mentoring in the Biological Sciences (2014)
BIOL 0500 - Cell and Molecular Biology |
BIOL 2000A - Current Topics in MCDB - RNA Regulation: Beyond the Central Dogma |
BIOL 2010A - Introduction to Molecular Research in the Life Sciences |
BIOL 2150 - Scientific Communication |