Matthew D. Jankowich, MD is an Associate Professor of Medicine at the Alpert Medical School of Brown University and is a staff physician and the Associate Chief of Staff for Education at the Providence VA Medical Center. Dr. Jankowich is a graduate of Dartmouth College and of the Ohio State University College of Medicine. He did his internship in internal medicine at the Yale-New Haven Hospital in New Haven, CT and completed his residency in internal medicine at Beth Israel Deaconess Medical Center in Boston, MA. He subsequently completed a fellowship in Pulmonary and Critical Care Medicine at Brown University, performing research in the Vascular Research Laboratory at the Providence VA Medical Center. After graduating from his fellowship, he took a staff position at the Providence VA Medical Center, where he is co-founder and co-director of the Pulmonary Hypertension clinic. Dr. Jankowich has interests in clinical pulmonary medicine as well as teaching and research. His clinical interests include lung cancer, pulmonary hypertension, and the use of ultrasound in pulmonary medicine, including endobronchial ultrasound. He was a course director for the Pulmonary physiology and pathophysiology section of BIOL 3662 IMS III from 2009-2019. His research interests include pulmonary hypertension epidemiology, pulmonary hypertension due to lung diseases, the COPD phenotype combined pulmonary fibrosis and emphysema, and the study of the interactions between lung function and systemic and pulmonary vascular disease.
| Gartman E, Jankowich M. "D for Destiny? Parameter D and Chronic Obstructive Pulmonary Disease." Annals of the American Thoracic Society, vol. 20, no. 7, 2023, pp. 953-954. |
| Li G, Jankowich MD, Wu L, Lu Y, Shao L, Lu X, Fan Y, Pan CW, Wu Y, Ke C. "Preserved Ratio Impaired Spirometry and Risks of Macrovascular, Microvascular Complications and Mortality Among Individuals With Type 2 Diabetes." Chest, 2023. |
| Li G, Jankowich MD, Lu Y, Wu L, Shao L, Ke C. "Preserved Ratio Impaired Spirometry, Metabolomics and the Risk of Type 2 Diabetes." The Journal of Clinical Endocrinology & Metabolism, 2023. |
| Meduri GU, Shih MC, Bridges L, Martin TJ, El-Solh A, Seam N, Davis-Karim A, Umberger R, Anzueto A, Sriram P, Lan C, Restrepo MI, Guardiola JJ, Buck T, Johnson DP, Suffredini A, Bell WA, Lin J, Zhao L, Uyeda L, Nielsen L, Huang GD, ESCAPe Study Group. "Low-dose methylprednisolone treatment in critically ill patients with severe community-acquired pneumonia." Intensive care medicine, 2022. |
| Branch-Elliman W, Ferguson R, Doros G, Woods P, Leatherman S, Strymish J, Datta R, Goswami R, Jankowich MD, Shah NR, Taylor TH, Page ST, Schiller SJ, Shannon C, Hau C, Flynn M, Holmberg E, Visnaw K, Dhond R, Brophy M, Monach PA. "Subcutaneous sarilumab for the treatment of hospitalized patients with moderate to severe COVID19 disease: A pragmatic, embedded randomized clinical trial." PLoS ONE, vol. 17, no. 2, 2022, pp. e0263591. |
| Maron BA, Choudhary G, Goldstein RL, Garshick E, Jankowich M, Tucker TJS, LaCerda KA, Hattler B, Dempsey EC, Sadikot RT, Shapiro S, Rounds SI, Goldstein RH. "Tadalafil for veterans with chronic obstructive pulmonary disease—pulmonary hypertension: A multicenter, placebo‐controlled randomized trial." Pulmonary Circulation, vol. 12, no. 1, 2022, pp. e12043. |
| Vayntrub Y, Gartman E, Nici L, Jankowich MD. "Diagnostic Performance of the Herder Model in Veterans Undergoing PET Scans for Pulmonary Nodule Evaluation." Lung, 2021. |
| Qureshi R, Vayntrub Y, Aswad B, Choudhary G, Jankowich M. "Dyspnea, Elevated Jugular Venous Pulse, and Lower Extremity Edema in the Setting of Interstitial Lung Disease in a Patient Who Has Undergone Liver and Kidney Transplantation." Chest, vol. 160, no. 3, 2021, pp. e295-e298. |
| Jankowich M, Maron BA, Choudhary G. "Mildly elevated pulmonary artery systolic pressure on echocardiography: bridging the gap in current guidelines." The Lancet Respiratory Medicine, 2021. |
| Zeba F, Yanning W, Melek J, Duan F, Atalay MK, Jankowich M, Rounds S. "Prognostic Significance of Pulmonary Artery to Aorta Ratio and Other CT Markers in Pulmonary Fibrosis With and Without Emphysema." Lung, vol. 199, no. 6, 2021, pp. 677-680. |
| Lee S, Lacy ME, Jankowich M, Correa A, Wu WC. "Association between obesity phenotypes of insulin resistance and risk of type 2 diabetes in African Americans: The Jackson Heart Study." Journal of Clinical & Translational Endocrinology, vol. 19, 2020, pp. 100210. |
| Lakshmanan, Suvasini, Jankowich, Matthew, Wu, Wen-Chih, Abbasi, Siddique, Morrison, Alan R, Choudhary, Gaurav. "Association of plasma adiponectin with pulmonary hypertension, mortality and heart failure in African Americans: Jackson Heart Study." Pulmonary Circulation, vol. 10, no. 4, 2020, pp. 204589402096124. |
| Vecchio, Marc J., Jankowich, Matthew, Qadir, Hassan, Gaitanis, Melissa, Menon, Anupama. "Cognitive Biases in the Era of COVID-19 : A Case of Clostridium sporogenes Bacteremia in a Patient with Small Bowel Obstruction." Case Reports in Infectious Diseases, vol. 2020, 2020, pp. 1-5. |
| Lakshmanan, Suvasini, Jankowich, Matthew, Wu, Wen‐Chih, Blackshear, Chad, Abbasi, Siddique, Choudhary, Gaurav. "Gender Differences in Risk Factors Associated With Pulmonary Artery Systolic Pressure, Heart Failure, and Mortality in Blacks: Jackson Heart Study." Journal of the American Heart Association, vol. 9, no. 1, 2020. |
| Jankowich M, Choudhary G. "Endothelin-1 levels and cardiovascular events." Trends in cardiovascular medicine, 2019. |
| Imran H, Jankowich M, Choudhary G. "Pulmonary Hypertension Post Liver-Kidney Transplant." Rhode Island medical journal (2013), vol. 102, no. 9, 2019, pp. 23-26. |
| Jankowich M, Abbasi SA, Vang A, Choudhary G. "Right Ventricular Fibrosis is Related to Pulmonary Artery Stiffness in Pulmonary Hypertension: A Cardiac Magnetic Resonance Imaging Study." Am J Respir Crit Care Med, 2019. |
| Kolte D, Lakshmanan S, Jankowich MD, Brittain EL, Maron BA, Choudhary G. "Mild Pulmonary Hypertension Is Associated With Increased Mortality: A Systematic Review and Meta-Analysis." Journal of the American Heart Association, vol. 7, no. 18, 2018, pp. e009729. |
| Gartman E, Jankowich M, Baptiste J, Schiff A, Nici L. "Outcomes of the First Three Years of a Lung Cancer Screening Program at a Veterans Affairs Medical Center." Annals of the American Thoracic Society, 2018. |
| Jankowich M, Elston B, Liu Q, Abbasi S, Wu WC, Blackshear C, Godfrey M, Choudhary G. "Restrictive Spirometry Pattern, Cardiac Structure and Function, and Incident Heart Failure in African Americans. The Jackson Heart Study." Annals of the American Thoracic Society, vol. 15, no. 10, 2018, pp. 1186-1196. |
| Jankowich M, Hebel R, Jantz J, Abbasi S, Choudhary G. "Multispecialty pulmonary hypertension clinic in the VA." Pulmonary Circulation, vol. 7, no. 4, 2017, pp. 2045893217726063. |
| Jankowich, Matthew D., Wu, Wen-Chih, Choudhary, Gaurav. "Association of Elevated Plasma Endothelin-1 Levels With Pulmonary Hypertension, Mortality, and Heart Failure in African American Individuals." JAMA Cardiology, vol. 1, no. 4, 2016, pp. 461. |
| Uppal P, LaPlante KL, Gaitanis MM, Jankowich MD, Ward KE. "Daptomycin-induced eosinophilic pneumonia - a systematic review." Antimicrobial resistance and infection control, vol. 5, 2016, pp. 55. |
| Okereke, Ikenna C., Bates, Maria F., Jankowich, Matthew D., Rounds, Sharon I., Kimble, Brian A., Baptiste, Janelle V., Ng, Thomas T., Nici, Linda L. "Effects of Implementation of Lung Cancer Screening at One Veterans Affairs Medical Center." Chest, vol. 150, no. 5, 2016, pp. 1023-1029. |
| Jankowich M, Elston B, Evans SK, Wu WC, Choudhary G. "Relationship of Iron Deficiency and Serum Ferritin Levels with Pulmonary Hypertension: The Jackson Heart Study." PLOS ONE, vol. 11, no. 12, 2016, pp. e0167987. |
| Wojtaszczyk A, Jankowich M. "Dyspnea on daptomycin: eosinophilic pneumonia." Rhode Island medical journal (2013), vol. 98, no. 6, 2015, pp. 41-3. |
| Steiner, Johannes, Wu, Wen-Chih, Jankowich, Matthew, Maron, Bradley A., Sharma, Satish, Choudhary, Gaurav. "Echocardiographic Predictors of Mortality in Patients with Pulmonary Hypertension and Cardiopulmonary Comorbidities." PLoS ONE, vol. 10, no. 3, 2015, pp. e0119277. |
| Godfrey MS, Jankowich MD. "The Vital Capacity is Vital: Epidemiology and Clinical Significance of the Restrictive Spirometry Pattern." Chest, 2015. |
| "Ultrasound in the Intensive Care Unit." Respiratory Medicine, 2015. |
| Choudhary G, Jankowich M, Wu WC. "Elevated pulmonary artery systolic pressure predicts heart failure admissions in African Americans: Jackson Heart Study." Circulation: Heart Failure, vol. 7, no. 4, 2014, pp. 558-64. |
| Evans, Samuel K., Jankowich, Matthew. "Pleural Ultrasound." Respiratory Medicine, 2014, pp. 207-233. |
| Maron BA, Choudhary G, Khan UA, Jankowich MD, McChesney H, Ferrazzani SJ, Gaddam S, Sharma S, Opotowsky AR, Bhatt DL, Rocco TP, Aragam JR. "Clinical profile and underdiagnosis of pulmonary hypertension in US veteran patients." Circulation: Heart Failure, vol. 6, no. 5, 2013, pp. 906-12. |
| Choudhary G, Jankowich M, Wu WC. "Prevalence and clinical characteristics associated with pulmonary hypertension in African-Americans." PLoS ONE, vol. 8, no. 12, 2013, pp. e84264. |
| Maron BA, Goldstein RH, Rounds SI, Shapiro S, Jankowich M, Garshick E, Moy ML, Gagnon D, Choudhary G. "Study design and rational for investigating phosphodiesterase type 5 inhibition for the treatment of pulmonary hypertension due to chronic obstructive lung disease: the TADA-PHiLD (TADAlafil for Pulmonary Hypertension associated with chronic obstructive Lung Disease) trial." 2013, vol. 3, no. 4, 2013, pp. 889-897. |
| Sears EH, Jankowich MD, Healey TT. "A slow growing non-calcified airway mass." Medicine and health, Rhode Island, vol. 95, no. 8, 2012, pp. 264-5. |
| Jankowich MD, Rounds SI. "Combined pulmonary fibrosis and emphysema syndrome: a review." Chest, vol. 141, no. 1, 2012, pp. 222-31. |
| Jankowich M, Choudhary G, Taveira TH, Wu WC. "Age-, race-, and gender-specific prevalence of diabetes among smokers." Diabetes Research and Clinical Practice, vol. 93, no. 3, 2011, pp. e101-5. |
| Lu Q, Jankowich M, Newton J, Harrington EO, Rounds S. "Alterations in molecular chaperones and eIF2alpha during lung endothelial cell apoptosis." American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 298, no. 4, 2010, pp. L501-8. |
| Jankowich MD, Rounds S. "Combined pulmonary fibrosis and emphysema alters physiology but has similar mortality to pulmonary fibrosis without emphysema." Lung, vol. 188, no. 5, 2010, pp. 365-73. |
| Jankowich MD, Taveira T, Wu WC. "Decreased lung function is associated with increased arterial stiffness as measured by peripheral pulse pressure: data from NHANES III." American Journal of Hypertension, vol. 23, no. 6, 2010, pp. 614-9. |
| Jankowich MD, Polsky M, Klein M, Rounds S. "Heterogeneity in combined pulmonary fibrosis and emphysema." Respiration; international review of thoracic diseases, vol. 75, no. 4, 2008, pp. 411-7. |
| Jankowich M, El-Sameed YA, Abu-Hijleh M. "A 21-year-old man with fever and sore throat rapidly progressive to hemoptysis and respiratory failure. Diagnosis: Lemierre syndrome with Fusobacterium necrophorum sepsis." Chest, vol. 132, no. 5, 2007, pp. 1706-9. |
| Lu Q, Harrington EO, Newton J, Jankowich M, Rounds S. "Inhibition of ICMT induces endothelial cell apoptosis through GRP94." American Journal of Respiratory Cell and Molecular Biology, vol. 37, no. 1, 2007, pp. 20-30. |
| Jankowich MD. "Idiopathic pulmonary fibrosis in transplantation." Chest, vol. 124, no. 6, 2003, pp. 2404; author reply 2404-5. |
2010-2011 Department of Medicine, Chairman's Developmental Research Grant. "The effect of pulmonary rehabilitation on systemic vascular function in COPD." $25,000/year x 1-2 years, awarded 11/2010.
2012-2013 The Rhode Island Foundation. "Effect of cardiovascular risk reduction on systemic vascular function in diabetics with COPD." Grant number 20113648. $13,790 x 1 year.
2012-2014 Site investigator, CSP#574 "Extended Steroid in CAP(e) (ESCAPe): A Randomized, Placebo-Controlled, Double-Blind Clinical Trial to Evaluate the Safety and Efficacy of Methylprednisolone in Hospitalized Veterans with Severe Community-Acquired Pneumonia". VA Cooperative Study. Local site budgetary support: $24,514 (in 2012); $58,930 (2013). --Study completed; results were published in Intensive Care Medicine in 2022.
2014-2019 Site Co-Investigator, Tadalafil for Pulmonary Hypertension Associated with Chronic Lung Disease (TADA-PHiLD) study. (Co-PIs: Ron Goldstein, Boston VA Medical Center, Sharon Rounds, Providence VA Medical Center) --This was a pivotal multicenter VA clinical trial evaluating the effect of phosphodiesterase-5 inhibition versus placebo for the treatment of pulmonary hypertension related to COPD (COPD-PH). The Pulmonary Hypertension clinic at the Providence VA served an important role in subject recruitment and evaluation. Study completed and study manuscript published in Pulmonary Circulation in 2022.
2017 Site Investigator, "Oxygen versus PAP for Treatment of Sleep Apnea in Chronic Heart Failure (OPTIMAL-HF) study." (PI: Daniel J. Gottlieb, M.D., M.P.H.). VA Merit Review CLIN-008-12S. Local site budgetary support: $40,000 (2017).
2020 Site Co-Principal Investigator, “Sarilumab for Patients with Moderate COVID-19 Disease: A Randomized Controlled Trial with a Play-The-Winner Design”. Funding mechanism pending. Industry support: None. ClinicalTrials.gov number: NCT04359901.Local site PI: Nishant Shah. Principal Investigator: Westyn Branch-Elliman. --Study completed; study results published in PLoS One in 2022.
2021-2022 Site Principal Investigator, Therapeutics for Inpatients with COVID-19 (TICO)/ACTIV-3 (INSIGHT 014). Funding: INSIGHT subaward #204-014-074025-P5. NCT04501978. Sponsor: University of Minnesota. Principal Investigator: Prof. Jens Lundgren. Local site budgetary support: $12,180. --Study completed; enrollment ended.
2022 Site Co-investigator, Evaluation of the Feasibility and Reproducibility of 2 Point-of-Care Tests for SARS-Co-V-2 Antibodies (EPOC)—INSIGHT-017. Funding: Funded by the National Institute of Allergy and Infectious Disease (NIAD), National Institutes of Health, and carried out by the International Network of Strategic Initiatives in Global HIV Trials (INSIGHT) and University of Minnesota. Site PI: Anupama Menon. Local site budgetary support: $5654. --Study completed; enrollment ended.
2023 Site Principal Investigator, Effect of PDE5 Inhibitor on Respiratory Symptoms in COPD Complicated by Pulmonary Hypertension or (Breathe Easier with Tadalafil Therapy for Exercise Related dyspnea in COPD-PH, “BETTER COPD-PH”). Funded by VA Office of Research and Development Clinical Science R+D grant (PI: Sharon Rounds).
Choudhary G, Jankowich M, Wu W-C. Elevated pulmonary artery systolic pressure predicts heart failure admissions in African Americans: Jackson Heart Study. Circulation: Heart Failure, 2014 Jun 5. pii: CIRCHEARTFAILURE.114.001366 [Epub ahead of print]. PMID: 24902739.
Maron BA, Choudhary G, Khan U, Jankowich MD, McChesney H, Ferrazzani SJ, Gaddam S, Sharma S, Opotowsky AR, Bhatt DL, Rocco TP, Aragam JR. The clinical profile and under-diagnosis of pulmonary hypertension in U.S. veteran patients. Circulation: Heart Failure 2013 Jun 27. [Epub ahead of print]. PMID: 23811965.
Jankowich MD. Idiopathic pulmonary fibrosis. In: First Consult. Editor-in-Chief Margaret T. Hessen, M.D., F.A.C.P.. Elsevier: Electronically published, February, 2013. (Electronic Publication)
Choudhary G, Jankowich M, Wu W-C. Prevalence and clinical characteristics associated with pulmonary hypertension in African-Americans. PLoS ONE 2013; 8(12): e84264. doi: 10.1371/journal.pone.0084264.
Jankowich MD, Rounds SI. Combined pulmonary fibrosis and emphysema syndrome—a review. Chest 2012; 141(1): 222-231. PMID: 22215830.
Jankowich MD, , Martin DW, Choudhary G. Cor Pulmonale. In: Ferri's Clinical Adviser 2013. Edited by Fred F. Ferri, M.D., F.A.C.P. Elsevier Mosby: Philadelphia 2012.
Jankowich MD, Ferri FF. Pulmonary edema. In: Ferri's Clinical Adviser 2013. Edited by Fred F. Ferri, M.D., F.A.C.P. Elsevier Mosby: Philadelphia 2012.
Jankowich MD, Ferri FF. Pulmonary embolism. In: Ferri's Clinical Adviser 2013. Edited by Fred F. Ferri, M.D., F.A.C.P. Elsevier Mosby: Philadelphia 2012.
Jankowich MD, Martin DW, Choudhary G. Pulmonary hypertension. In: Ferri's Clinical Adviser 2013. Edited by Fred F. Ferri, M.D., F.A.C.P. Elsevier Mosby: Philadelphia 2012.
Jankowich M, Choudhary G, Taveira TH, Wu WC. Age-, race-, and gender-specific prevalence of diabetes among smokers. Diabetes Res Clin Pract 2011; 93: 101-105.
Jankowich M. Thoracic malignancies. In: Chronic Obstructive Pulmonary Disease: Co-Morbidities and Systemic Consequences, first edition. Edited by Linda Nici, M.D. and Richard ZuWallack, M.D. Humana Press, Springer; New York 2012.
Jankowich M, Taveira T, Wu W-C. Decreased lung function is associated with increased arterial stiffness as measured by peripheral pulse pressure: data from NHANES III. Am J Hypertens 2010; 23: 614-619.
Lu Q*, Jankowich M*, Newton J, Harrington EO, Rounds S. Alterations in molecular chaperones and EIF2α during lung endothelial cell apoptosis. Amer J Physiol: Lung Cellular and Molecular Physiology 2010; 298: L501-L508. (*Equal contributions).
Rounds S and Jankowich MD. The Lung in Health and Disease. In: Andreoli and Carpenter's Cecil Essentials of Medicine, eighth edition. Edited by Thomas E. Andreoli et al. Saunders Elsevier. Philadelphia, 2010.
Jankowich MD. Obstructive Lung Diseases. In: Andreoli and Carpenter's Cecil Essentials of Medicine, eighth edition. Edited by Thomas E. Andreoli et al. Saunders Elsevier. Philadelphia, 2010.
Aliotta JA and Jankowich MD. Interstitial Lung Disease. In: Andreoli and Carpenter's Cecil Essentials of Medicine, eighth edition. Edited by Thomas E. Andreoli et al. Saunders Elsevier. Philadelphia, 2010.
Rounds S and Jankowich MD. Disorders of Respiratory Control. In: Andreoli and Carpenter's Cecil Essentials of Medicine, eighth edition. Edited by Thomas E. Andreoli et al. Saunders Elsevier. Philadelphia, 2010.
Aliotta JA and Jankowich MD. Neoplastic Disorders of the Lung. In: Andreoli and Carpenter's Cecil Essentials of Medicine, eighth edition. Edited by Thomas E. Andreoli et al. Saunders Elsevier. Philadelphia, 2010.
Jankowich MD, Rounds S. Combined pulmonary fibrosis and emphysema results in altered physiology but has similar mortality to pulmonary fibrosis without emphysema. Lung 2010. July 8. Epublished before print. PMID 20614219.
Jankowich M, Choudhary G, and Rounds S. Hypoxia and the Pulmonary Endothelium. In: The Pulmonary Endothelium: Function in Health and Disease. Edited by Sharon Rounds and Norbert Voelkel. John Wiley and Sons, LTD., 2009.
Jankowich M, Polsky M., Klein M, and Rounds S. Heterogeneity in combined pulmonary fibrosis and emphysema. Respiration 2008; 75: 411-417.
Jankowich M, Sameed YA, and Abu-Hijleh, M. A 21-year-old man with fever and sore throat rapidly progressive to hemoptysis and respiratory failure. Diagnosis: Lemierre syndrome with Fusobacterium necrophorum sepsis. Chest 2007; 132: 1706-1709.
Lu Q, Harrington EO, Newton J, Jankowich M, and Round S. Inhibition of ICMT induces endothelial cell apoptosis through GRP94. Am J Respir Cell Mol Biol 2007; 37(1): 20-30.
Jankowich MD, Wahidi MM, Feller-Kopman D, and Ernst A. Pulmonary alveolar proteinosis diagnosed in pregnancy and managed with whole-lung lavage. J Bronchol 2006; 13: 204-206.
| Year | Degree | Institution |
|---|---|---|
| 1999 | MD | Ohio State University |
| 1994 | AB | Dartmouth College |
2019: Dean's Excellence in Teaching Award, Warren Alpert Medical School of Brown University, Clerkship in Medicine
2018: Master of Arts ad eundem, Brown University
2016: Dean's Excellence in Teaching Award, Warren Alpert Medical School of Brown University, BIOL 3662 IMS III: Pulmonary
2015: Teacher of the Year Award, Division of Pulmonary, Sleep and Critical Care Medicine, Warren Alpert Medical School of Brown University
2014-2015: President, Rhode Island Thoracic Society
2012: Dean's Excellence in Teaching Award, Warren Alpert Medical School of Brown University, BIOL 3662: IMS III: Pulmonary
| Name | Title |
|---|---|
| Choudhary, Gaurav | Ruth and Paul Levinger Professor of Cardiology |
| Gartman, Eric | Associate Professor of Medicine |
| Imran, Tasnim | Assistant Professor of Medicine |
| Nici, Linda | Professor of Medicine, Clinician Educator |
| Rounds, Sharon | Associate Dean for Translational Science, Professor of Medicine, Professor of Pathology and Laboratory Medicine |
| Taveira, Tracey | Adjunct Professor of Medicine |
| Wu, Wen-Chih | Professor of Medicine, Professor of Epidemiology |
| BIOL 3663 - IMS-3 Pulmonary |
