Albert C. Lo, M.D., Ph.D. is an Associate Professor in the Departments of Neurology and Epidemiology of Brown University, and is an Associate Director of the Center for Neurorestoration and Neurotechnology at the Providence VA Medical Center. He is board certified by the American Board of Psychiatry and Neurology. Dr. Lo received his B.A. degree in Biochemistry from the University of California at Berkeley. He then received a C.P.H. degree from Harvard University and subsequently earned his M.D. and Ph.D. degree in neuroscience from the Wake Forest University School of Medicine in North Carolina. Dr. Lo completed his internship and neurology residency at Yale. From 2001 until 2007, Dr. Lo was on the faculty at the Yale School of Medicine in the Department of Neurology, and was director of the Multiple Sclerosis Clinic and Neurorehabilitation Research Laboratory at VA Connecticut Healthcare System West Haven. Dr. Lo served on the VA Spinal Cord Injury Scientific Review Board, the Brown Biomedical Engineering Executive Advisory Council. He is a current memember of Medical School and PLME Admission Committees, the VA Multiple Sclerosis Center of Excellence Research Advisory Panel, the American Academy of Neurology Author Panel for Practice Parameter Guidelines and the Executive Steering Committee of the Mandell MS Center in Hartford, Connecticut. He is also the Director of Neuroscience Research at the Mandell Multiple Sclerosis Center in Hartford CT. In 2004, Dr. Lo received the Presidential Early Career Award for Scientists and Engineers from the White House Office of Science and Technology Policy.
Gianfrancesco MA, Triche EW, Fawcett JA, Labas MP, Patterson TS, Lo AC. (2011). Speed- and cane-related alterations in gait parameters in individuals with multiple sclerosis. Gait and Posture. 33:140-142.
Wier LM, Hatcher MS, Triche EW, Lo AC. (2011). Effect of Body-Weight Supported Treadmill Training with and without Robotic Assistance on Quality of Life for People with Multiple Sclerosis. Journal of Rehabilitation Research and Development. 48: (In Press).
Schmid AA, Kapoor JR, Miech EJ, Kuehn D, Dallas MI, Kerns RD, Lo AC, Concato J, Phipps M, Couch CD, Moran E, Williams LS, Goble LA, Bravata DM. (2010). A Multidisciplinary Stroke Clinic for the Outpatient Care of Veterans with Cerebrovascular Disease. Journal of Multidisciplinary Healthcare. (In press).
Wagner TH, Lo AC, Peduzzi P, Bravata DM, Huang GD, Krebs HI, Ringer RJ, Federman DG, Richards LG, Haselkorn JK, Wittenberg GF, Volpe BT, Bever CT, Duncan PW, Siroka A, Guarino P. (2011). An economic analysis of robot-assisted therapy for long-term upper-limb impairment after stroke. Stroke (In Press).
Chumbler NR, Williams LS, Wells CK, Lo AC, Nadeau S, Peixoto AJ, Gorman M, Boice JL, Concato J, Bravata DM. (2010). Derivation and Validation of a Clinical System for Predicting Pneumonia in Acute Stroke. Neuroepidemiology. 34(4):193-9.
Bravata DM, Wells CK, Lo AC, Nadeau S, Melillo J, Chodkowski D, Struve F, Williams LS, Peixoto AJ, Gorman M, Goel P, Acompora G, McClain V, Ranjbar N, Tabereaux PB, Boice JL, Jacewicz M, Brass LM, Concato J. (2010). Processes of Care Associated with Acute Stroke Outcomes. Archives of Internal Medicine. 170(9):804-810.
Bravata DM, Concato J, Fried T, Ranjbar N, Sadarangani T, McClain V, Struve F, Zygmunt L, Knight H, Lo A, Richerson G, Gorman M, Williams LS, Brass LM, Agostini N, Mohsenin V, Roux F, Yaggi HK. (2010). Auto-Titrating Continuous Positive Airway Pressure for Patients with Acute Transient Ischemic Attack: A Randomized Feasibility Trial. Stroke. 41(7):1464-70.
Lo AC, Chang VC, Gianfrancesco MA, Friedman JH, Patterson TS, Benedicto DF. (2010). Reduction of freezing of gait in Parkinson's disease by repetitive robot-assisted treadmill training. Journal of Neuroengineering and Rehabilitation. 7(1): 51-8.
Schmid A, Wells CK, Concato J, Dallas MI, Lo AC, Nadeau S, Williams LS, Peixoto A, Gorman M, Boice JL, Struve F, McClain V, Bravata DM. (2010). Prevalence, Predictors, and Outcomes of Post-Stroke Falls in the Acute Hospital Setting. Journal of Rehabilitation Research and Development. 47(6):553-62.
Lo AC, Guarino P, Richards LG, Haselkorn JK, Wittenberg GF, Federman DG, Ringer RJ, Wagner TH, Bever CT, Krebs HI, Volpe BT, Bravata DM, Duncan PW Corn BH, Maffucci AD, Nadeau MD, Conroy, Powell JM, Huang GD, Peduzzi P. (2010). Robot-assisted therapy for long-term impairment after stroke. New England Journal of Medicine. 362(19):1772-1783.
Lo AC, Guarino P, Krebs HI, Volpe BT, Bever CT, Duncan PW, Ringer RJ, Wagner TH, Richards LG, Bravata DM, Haselkorn JK, Wittenberg GF, Federman DG, Corn BH, Maffucci AD, Peduzzi P. (2009). Multi-center Randomized Trial of Robot-Assisted Rehabilitation for Chronic Stroke: Methods and Entry Characteristics for VA ROBOTICS. Neurorehabilitation and Neural Repair. 23:775-785.
Krebs HI, Dipietro L, Levy-Tzedek S, Fasoli S, Rykman A, Zipse J, Fawcett J, Stein J, Poizner H, Lo AC, Volpe B, Hogan N. (2008). A Paradigm-Shift: Rehabilitation Robotics. IEEE--Engineering in Medicine and Biology. 7:61-70.
Lo AC. (2008). Advancement of therapies for neuroprotection in multiple sclerosis. Expert Reviews of Neurotherapeutics. 8(9):1355-1366.
Lo AC, Triche EW. (2008). Improving gait in multiple sclerosis using robot-assisted, body weight supported treadmill training. Neurorehabilitation and Neural Repair. 22:661-671.
Lo AC, Hadjimichael O, Vollmer TL. (2005). Treatment patterns of multiple sclerosis patients: A comparison of veterans and non-veterans using the NARCOMS registry. Multiple Sclerosis. 11:33-40.
Hains BC, Saab CY, Lo AC, Black JA, Waxman SG. (2004). Sodium channel blockade with phenytoin protects spinal cord axons, enhances axonal recovery, and improves functional motor recovery after contusion SCI. Experimental Neurology. 188:365-377.
Craner MJ, Damarjian TG, Liu S, Hains BC, Lo AC, Black JA, Newcombe J, Cuzner ML, Waxman SG. (2004). Sodium channels contribute to microglial and macrophage activation and function in EAE and MS. Glia. 49:220-229.
Craner MJ, Hains BC, Lo AC, Black JA, Waxman SG. (2004). Co-localization of sodium channel Na 1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE. Brain. 127: 294-303.
Craner MJ, Lo AC, Black JA, Baker D, Newcombe J, Cuzner L, Waxman SG. (2003). Annexin II/p11 is upregulated in purkinje cells in EAE and MS. NeuroReport. 14:555-558.
Craner MJ, Lo AC, Rasband MN, Black JA, Waxman SG. (2003). Abnormal sodium channel distribution in the optic nerve in a model of inflammatory demyelination. Brain. 126:1552-1561.
Craner MJ, Kataoka Y, Lo AC, Black JA, Baker D, Waxman SG. (2003). Temporal course of upregulation of Nav1.8 in in purkinje neurons parallels the progression of clinical deficit in EAE. Journal of Neuropathology and Experimental Neurology. 62:968-975.
Lo AC, Saab CY, Black JA, Waxman SG. (2003). Phenytoin protects spinal cord axons and preserves axonal conduction and neurological function in a model of neuroinflammation in vivo. Journal of Neurophysiology. 90: 3566-3571.
Lo AC, Black JA, Waxman SG. (2002). Neuroprotection of axons with phenytoin in experimental allerigic encephalomyelitis. NeuroReport. 13:1909-1912.
Mattson DH, Lo AC, Auld E. (2002). Disorders that Mimic Multiple Sclerosis. Multiple Sclerosis Quarterly Report 21:12-16.
Gould TW, Burek MJ, Ishihara R, Lo AC, Prevette D, Oppenheim RW. (1999). Androgens rescue avian embryonic lumbar spinal motoneurons from injury-induced but not naturally occurring cell death. Journal of Neurobiology. 41:585-95.
Houenou LJ, Oppenheim RW, Li L, Lo AC, Prevette D. (1996). Regulation of spinal motoneuron survival by GDNF during development and following injury. Cell and Tissue Research. 286:219-223.
Lo AC, Houenou LJ, Oppenheim RW. (1995). Apoptosis in the nervous system: morphological features, methods, pathology and prevention. Archives of Histology and Cytology. (Special Edition) 58:139-149.
Oppenheim RW, Houenou LJ, Johnson JE, Leu-Fen HL, Li L, Lo AC, Newsome AL, Prevette DM, Wang S. (1995). Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF. Nature. 373:344-346.
Lo AC, Li L, Oppenheim RW, Prevette D, Houenou LJ. (1995). Ciliary neurotrophic factor (CNTF) promotes survival of spinal sensory neurons following axotomy but not during the period of programmed cell death. Experimental Neurology. 134:49-55.
Houenou LJ, Prevette DM, Lo AC, Li L, Oppenheim RW. (1994). Motor neuron tropic agents: In vivo studies during embryogenesis. Muscle Nerve. 1:S20.
Houenou LJ, Lo AC, Yan Q, Oppenheim RW. (1994). Naturally occurring and axotomy-induced motoneuron death and its prevention by neurotrophic agents: A comparison between chick and mouse. Progress in Brain Research. 102:217-226.
|1997||PhD||Wake Forest University|
|1997||MD||Wake Forest University|
|1987||BA||University of California, Berkeley|
|Fellow||National Hospital of Neurology and Neurosurgery, Queen Square, neurorehabilitation||2001-||London, UK|
|Resident||Yale School of Medicine, neurology||1998-2001||New Haven, CT|
|Intern||Yale School of Medicine||1997-1998||New Haven, CT|
|St. Francis Hospital||2007-2030||#Hartford, CT|
|Providence VA Medical Center||2007-2030||#Providence, RI|
|Yale New Haven Hospital||2005-2008||#New Haven, CT|
|American Board of Psychiatry and Neurology||2005-|
|Credentialing: Gaylord Hospital||2002-2008||#Wallingford, CT|
|VA Connecticut Healthcare Systems||2001-2009||#CT|
|Associate Director. Providence VA Medical Center, VA RRD Center of Excellence, Center for Neurorestoration and Neurotechnology, PVAMC 2012-Present|
|Associate Director. Providence VA Medical Center, VA RRD Center of Excellence, Center for Restorative and Regenerative Medicine, Providence VA Medical Center 2010-2012|
|Director. Providence VA Medical Center, Multiple Sclerosis Clinic 2007-Present|
|Director. Mount Sinai Hospital, Department of Neuroscience Research, Joyce D. and Andrew J Mandell Multiple Sclerosis Center 2007-Present|
|Attending Neurologist. VA Connecticut, Multidisciplinary Stroke Clinic 2006-2007|
|Director. VA Connecticut, Multiple Sclerosis Clinic 2003-2007|
|Staff Physician. VA Connecticut, Multiple Sclerosis Clinic 2002-2007|