Carr, Jennifer F., Danziger, Michael E., Huang, Athena L., Dahlberg, Albert E., Gregory, Steven T. Engineering the Genome of Thermus thermophilus Using a Counterselectable Marker. Journal of bacteriology. 2015; 197 (6) : 1135-1144. |
Carr, Jennifer F., Gregory, Steven T., Dahlberg, Albert E. Transposon mutagenesis of the extremely thermophilic bacterium Thermus thermophilus HB27. Extremophiles. 2014; 19 (1) : 221-228. |
Demirci H, Murphy F 4th, Murphy E, Gregory ST, Dahlberg AE, Jogl G A structural basis for streptomycin-induced misreading of the genetic code.. Nat Comms. 2013; 4 : 1355. |
Demirci H, Sierra RG, Laksmono H, Shoeman RL, Botha S, Barends TR, Nass K, Schlichting I, Doak RB, Gati C, Williams GJ, Boutet S, Messerschmidt M, Jogl G, Dahlberg AE, Gregory ST, Bogan MJ Serial femtosecond X-ray diffraction of 30S ribosomal subunit microcrystals in liquid suspension at ambient temperature using an X-ray free-electron laser.. Acta crystallographica. Section F, Structural biology and crystallization communications. 2013; 69 (Pt 9) : 1066-9. |
Demirci H, Wang L, Murphy FV 4th, Murphy EL, Carr JF, Blanchard SC, Jogl G, Dahlberg AE, Gregory ST The central role of protein S12 in organizing the structure of the decoding site of the ribosome.. RNA. 2013; 19 (12) : 1791-801. |
Monshupanee T, Johansen SK, Dahlberg AE, Douthwaite S Capreomycin susceptibility is increased by TlyA-directed 2'-O-methylation on both ribosomal subunits.. Molecular Microbiology. 2012; 85 (6) : 1194-203. |
Hall EH, Gurel V, Dahlberg AE, McMichael J, Brautigan DL Inhibition of human breast cancer Matrigel invasion by Streptolysin O activation of the EGF receptor ErbB1.. Cellular signalling. 2011; 23 (12) : 1972-7. |
Demirci H, Murphy F 4th, Belardinelli R, Kelley AC, Ramakrishnan V, Gregory ST, Dahlberg AE, Jogl G Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function.. RNA. 2010; 16 (12) : 2319-24. |
Gregory ST, Carr JF, Dahlberg AE A signal relay between ribosomal protein S12 and elongation factor EF-Tu during decoding of mRNA.. RNA. 2009; 15 (2) : 208-14. |
Gregory ST, Dahlberg AE Genetic and structural analysis of base substitutions in the central pseudoknot of Thermus thermophilus 16S ribosomal RNA.. RNA. 2009; 15 (2) : 215-23. |
Gregory ST, Demirci H, Belardinelli R, Monshupanee T, Gualerzi C, Dahlberg AE, Jogl G Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG.. RNA. 2009; 15 (9) : 1693-704. |
Demirci H, Belardinelli R, Seri E, Gregory ST, Gualerzi C, Dahlberg AE, Jogl G Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine.. Journal of molecular biology. 2009; 388 (2) : 271-82. |
Demirci H, Gregory ST, Dahlberg AE, Jogl G Crystal structure of the Thermus thermophilus 16 S rRNA methyltransferase RsmC in complex with cofactor and substrate guanosine.. Journal of Biological Chemistry. 2008; 283 (39) : 26548-56. |
Brandi L, Fabbretti A, Pon CL, Dahlberg AE, Gualerzi CO Initiation of protein synthesis: a target for antimicrobials.. Expert opinion on therapeutic targets. 2008; 12 (5) : 519-34. |
Rodriguez-Correa D, Dahlberg AE Kinetic and thermodynamic studies of peptidyltransferase in ribosomes from the extreme thermophile Thermus thermophilus.. RNA. 2008; 14 (11) : 2314-8. |
Demirci H, Gregory ST, Dahlberg AE, Jogl G Multiple-site trimethylation of ribosomal protein L11 by the PrmA methyltransferase.. Structure (London, England : 1993). 2008; 16 (7) : 1059-66. |
Monshupanee T, Gregory ST, Douthwaite S, Chungjatupornchai W, Dahlberg AE Mutations in conserved helix 69 of 23S rRNA of Thermus thermophilus that affect capreomycin resistance but not posttranscriptional modifications.. Journal of bacteriology. 2008; 190 (23) : 7754-61. |
Kapralou S, Fabbretti A, Garulli C, Spurio R, Gualerzi CO, Dahlberg AE, Pon CL Translation initiation factor IF1 of Bacillus stearothermophilus and Thermus thermophilus substitute for Escherichia coli IF1 in vivo and in vitro without a direct IF1-IF2 interaction.. Molecular Microbiology. 2008; 70 (6) : 1368-77. |
Gregory ST, Dahlberg AE Transposition of an insertion sequence, ISTth7, in the genome of the extreme thermophile Thermus thermophilus HB8.. FEMS microbiology letters. 2008; 289 (2) : 187-92. |
Demirci H, Gregory ST, Dahlberg AE, Jogl G Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA.. EMBO J. 2007; 26 (2) : 567-77. |
Carr JF, Hamburg DM, Gregory ST, Limbach PA, Dahlberg AE Effects of streptomycin resistance mutations on posttranslational modification of ribosomal protein S12.. Journal of bacteriology. 2006; 188 (5) : 2020-3. |
Schuwirth BS, Day JM, Hau CW, Janssen GR, Dahlberg AE, Cate JH, Vila-Sanjurjo A Structural analysis of kasugamycin inhibition of translation.. Nature structural & molecular biology. 2006; 13 (10) : 879-86. |
Gregory ST, Carr JF, Dahlberg AE A mutation in the decoding center of Thermus thermophilus 16S rRNA suggests a novel mechanism of streptomycin resistance.. Journal of bacteriology. 2005; 187 (6) : 2200-2. |
Suh MJ, Hamburg DM, Gregory ST, Dahlberg AE, Limbach PA Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry.. PROTEOMICS. 2005; 5 (18) : 4818-31. |
Gregory ST, Carr JF, Rodriguez-Correa D, Dahlberg AE Mutational analysis of 16S and 23S rRNA genes of Thermus thermophilus.. Journal of bacteriology. 2005; 187 (14) : 4804-12. |
Carr JF, Gregory ST, Dahlberg AE Severity of the streptomycin resistance and streptomycin dependence phenotypes of ribosomal protein S12 of Thermus thermophilus depends on the identity of highly conserved amino acid residues.. Journal of bacteriology. 2005; 187 (10) : 3548-50. |
Thompson J, Pratt CA, Dahlberg AE Effects of a number of classes of 50S inhibitors on stop codon readthrough during protein synthesis.. Antimicrobial Agents and Chemotherapy. 2004; 48 (12) : 4889-91. |
Rodriguez-Correa D, Dahlberg AE Genetic evidence against the 16S ribosomal RNA helix 27 conformational switch model.. RNA. 2004; 10 (1) : 28-33. |
O'Connor M, Gregory ST, Dahlberg AE Multiple defects in translation associated with altered ribosomal protein L4.. Nucleic acids research. 2004; 32 (19) : 5750-6. |
Gregory ST, Dahlberg AE Peptide bond formation is all about proximity.. Nature structural & molecular biology. 2004; 11 (7) : 586-7. |
Thompson J, Dahlberg AE Testing the conservation of the translational machinery over evolution in diverse environments: assaying Thermus thermophilus ribosomes and initiation factors in a coupled transcription-translation system from Escherichia coli.. Nucleic acids research. 2004; 32 (19) : 5954-61. |
Bayfield MA, Thompson J, Dahlberg AE The A2453-C2499 wobble base pair in Escherichia coli 23S ribosomal RNA is responsible for pH sensitivity of the peptidyltransferase active site conformation.. Nucleic acids research. 2004; 32 (18) : 5512-8. |
Cameron DM, Gregory ST, Thompson J, Suh MJ, Limbach PA, Dahlberg AE Thermus thermophilus L11 methyltransferase, PrmA, is dispensable for growth and preferentially modifies free ribosomal protein L11 prior to ribosome assembly.. Journal of bacteriology. 2004; 186 (17) : 5819-25. |
Cameron DM, Thompson J, Gregory ST, March PE, Dahlberg AE Thiostrepton-resistant mutants of Thermus thermophilus.. Nucleic acids research. 2004; 32 (10) : 3220-7. |
Brunelli CA, O'Connor M, Dahlberg AE Decreased requirement for 4.5S RNA in 16S and 23S rRNA mutants of Escherichia coli.. FEBS Letters. 2002; 514 (1) : 44-8. |
Pond-Tor S, Rhodes RG, Dahlberg PE, Leith JT, McMichael J, Dahlberg AE Enhancement of radiosensitivity of the MCF-7 breast cancer cell line with human chorionic gonadotropin.. Breast cancer research and treatment. 2002; 72 (1) : 45-51. |
Cameron DM, Thompson J, March PE, Dahlberg AE Initiation factor IF2, thiostrepton and micrococcin prevent the binding of elongation factor G to the Escherichia coli ribosome.. Journal of molecular biology. 2002; 319 (1) : 27-35. |
O'Connor M, Dahlberg AE Isolation of spectinomycin resistance mutations in the 16S rRNA of Salmonella enterica serovar Typhimurium and expression in Escherichia coli and Salmonella.. Current microbiology. 2002; 45 (6) : 429-33. |
Thompson J, O'Connor M, Mills JA, Dahlberg AE The protein synthesis inhibitors, oxazolidinones and chloramphenicol, cause extensive translational inaccuracy in vivo.. Journal of molecular biology. 2002; 322 (2) : 273-9. |
Bayfield MA, Dahlberg AE, Schulmeister U, Dorner S, Barta A A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition.. Proceedings of the National Academy of Sciences. 2001; 98 (18) : 10096-101. |
O'Connor M, Gregory ST, Rajbhandary UL, Dahlberg AE Altered discrimination of start codons and initiator tRNAs by mutant initiation factor 3.. RNA. 2001; 7 (7) : 969-78. |
Thompson J, Kim DF, O'Connor M, Lieberman KR, Bayfield MA, Gregory ST, Green R, Noller HF, Dahlberg AE Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit.. Proceedings of the National Academy of Sciences. 2001; 98 (16) : 9002-7. |
O'Connor M, Dahlberg AE Enhancement of translation by the epsilon element is independent of the sequence of the 460 region of 16S rRNA.. Nucleic acids research. 2001; 29 (7) : 1420-5. |
La Teana A, Gualerzi CO, Dahlberg AE Initiation factor IF 2 binds to the alpha-sarcin loop and helix 89 of Escherichia coli 23S ribosomal RNA.. RNA. 2001; 7 (8) : 1173-9. |
O'Connor M, Lee WM, Mankad A, Squires CL, Dahlberg AE Mutagenesis of the peptidyltransferase center of 23S rRNA: the invariant U2449 is dispensable.. Nucleic acids research. 2001; 29 (3) : 710-5. |
Vila-Sanjurjo A, Dahlberg AE Mutational analysis of the conserved bases C1402 and A1500 in the center of the decoding domain of Escherichia coli 16 S rRNA reveals an important tertiary interaction.. Journal of molecular biology. 2001; 308 (3) : 457-63. |
Gregory ST, Bayfield MA, O'Connor M, Thompson J, Dahlberg AE Probing ribosome structure and function by mutagenesis.. Cold Spring Harbor Symposia on Quantitative Biology. 2001; 66 : 101-8. |
Dahlberg AE Ribosome structure. The ribosome in action.. Science. 2001; 292 (5518) : 868-9. |
Gregory ST, Cate JH, Dahlberg AE Spontaneous erythromycin resistance mutation in a 23S rRNA gene, rrlA, of the extreme thermophile Thermus thermophilus IB-21.. Journal of bacteriology. 2001; 183 (14) : 4382-5. |
Thompson J, Tapprich WE, Munger C, Dahlberg AE Staphylococcus aureus domain V functions in Escherichia coli ribosomes provided a conserved interaction with domain IV is restored.. RNA. 2001; 7 (8) : 1076-83. |
Gregory ST, Cate JH, Dahlberg AE Streptomycin-resistant and streptomycin-dependent mutants of the extreme thermophile Thermus thermophilus.. Journal of molecular biology. 2001; 309 (2) : 333-8. |
Gabashvili IS, Gregory ST, Valle M, Grassucci R, Worbs M, Wahl MC, Dahlberg AE, Frank J The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22.. Molecular Cell. 2001; 8 (1) : 181-8. |
Koosha H, Cameron D, Andrews K, Dahlberg AE, March PE Alterations in the peptidyltransferase and decoding domains of ribosomal RNA suppress mutations in the elongation factor G gene.. RNA. 2000; 6 (8) : 1166-73. |
Sergiev PV, Bogdanov AA, Dahlberg AE, Dontsova O Mutations at position A960 of E. coli 23 S ribosomal RNA influence the structure of 5 S ribosomal RNA and the peptidyltransferase region of 23 S ribosomal RNA.. Journal of molecular biology. 2000; 299 (2) : 379-89. |
O'Connor M, Asai T, Squires CL, Dahlberg AE Enhancement of translation by the downstream box does not involve base pairing of mRNA with the penultimate stem sequence of 16S rRNA.. Proceedings of the National Academy of Sciences. 1999; 96 (16) : 8973-8. |
Gregory ST, Dahlberg AE Erythromycin resistance mutations in ribosomal proteins L22 and L4 perturb the higher order structure of 23 S ribosomal RNA.. Journal of molecular biology. 1999; 289 (4) : 827-34. |
Vila-Sanjurjo A, Squires CL, Dahlberg AE Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.. Journal of molecular biology. 1999; 293 (1) : 1-8. |
Gabashvili IS, Agrawal RK, Grassucci R, Squires CL, Dahlberg AE, Frank J Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA.. EMBO J. 1999; 18 (22) : 6501-7. |
Bläsi U, O'Connor M, Squires CL, Dahlberg AE Misled by sequence complementarity: does the DB-anti-DB interaction withstand scientific scrutiny?. Molecular Microbiology. 1999; 33 (2) : 439-41. |
Gregory ST, Dahlberg AE Mutations in the conserved P loop perturb the conformation of two structural elements in the peptidyl transferase center of 23 S ribosomal RNA.. Journal of molecular biology. 1999; 285 (4) : 1475-83. |
Gregory ST, Brunelli CA, Lodmell JS, O'Connor M, Dahlberg AE Genetic selection of rRNA mutations.. Methods in Molecular Biology. 1998; 77 : 271-81. |
Firpo MA, Dahlberg AE The importance of base pairing in the penultimate stem of Escherichia coli 16S rRNA for ribosomal subunit association.. Nucleic acids research. 1998; 26 (9) : 2156-60. |
Lodmell JS, Dahlberg AE A conformational switch in Escherichia coli 16S ribosomal RNA during decoding of messenger RNA.. Science. 1997; 277 (5330) : 1262-7. |
O'Connor M, Thomas CL, Zimmermann RA, Dahlberg AE Decoding fidelity at the ribosomal A and P sites: influence of mutations in three different regions of the decoding domain in 16S rRNA.. Nucleic acids research. 1997; 25 (6) : 1185-93. |
Gregory ST, O'Connor M, Dahlberg AE Functional Escherichia coli 23S rRNAs containing processed and unprocessed intervening sequences from Salmonella typhimurium.. Nucleic acids research. 1996; 24 (24) : 4918-23. |
Firpo MA, Connelly MB, Goss DJ, Dahlberg AE Mutations at two invariant nucleotides in the 3'-minor domain of Escherichia coli 16 S rRNA affecting translational initiation and initiation factor 3 function.. Journal of Biological Chemistry. 1996; 271 (9) : 4693-8. |
O'Connor M, Dahlberg AE The influence of base identity and base pairing on the function of the alpha-sarcin loop of 23S rRNA.. Nucleic acids research. 1996; 24 (14) : 2701-5. |
Santer UV, Cekleniak J, Kansil S, Santer M, O'Connor M, Dahlberg AE A mutation at the universally conserved position 529 in Escherichia coli 16S rRNA creates a functional but highly error prone ribosome.. RNA. 1995; 1 (1) : 89-94. |
Gregory ST, Dahlberg AE Effects of mutations at position 36 of tRNA(Glu) on missense and nonsense suppression in Escherichia coli.. FEBS Letters. 1995; 361 (1) : 25-8. |
Lodmell JS, Gutell RR, Dahlberg AE Genetic and comparative analyses reveal an alternative secondary structure in the region of nt 912 of Escherichia coli 16S rRNA.. Proceedings of the National Academy of Sciences. 1995; 92 (23) : 10555-9. |
O'Connor M, Brunelli CA, Firpo MA, Gregory ST, Lieberman KR, Lodmell JS, Moine H, Van Ryk DI, Dahlberg AE Genetic probes of ribosomal RNA function.. Biochemistry and cell biology = Biochimie et biologie cellulaire. 1995; 73 (11-12) : 859-68. |
Gregory ST, Dahlberg AE Nonsense suppressor and antisuppressor mutations at the 1409-1491 base pair in the decoding region of Escherichia coli 16S rRNA.. Nucleic acids research. 1995; 23 (21) : 4234-8. |
Lieberman KR, Dahlberg AE Ribosome-catalyzed peptide-bond formation.. Progress in nucleic acid research and molecular biology. 1995; 50 : 1-23. |
Van Ryk DI, Dahlberg AE Structural changes in the 530 loop of Escherichia coli 16S rRNA in mutants with impaired translational fidelity.. Nucleic acids research. 1995; 23 (17) : 3563-70. |
O'Connor M, Dahlberg AE The involvement of two distinct regions of 23 S ribosomal RNA in tRNA selection.. Journal of molecular biology. 1995; 254 (5) : 838-47. |
Moine H, Dahlberg AE Mutations in helix 34 of Escherichia coli 16 S ribosomal RNA have multiple effects on ribosome function and synthesis.. Journal of molecular biology. 1994; 243 (3) : 402-12. |
Gregory ST, Lieberman KR, Dahlberg AE Mutations in the peptidyl transferase region of E. coli 23S rRNA affecting translational accuracy.. Nucleic acids research. 1994; 22 (3) : 279-84. |
Lieberman KR, Dahlberg AE The importance of conserved nucleotides of 23 S ribosomal RNA and transfer RNA in ribosome catalyzed peptide bond formation.. Journal of Biological Chemistry. 1994; 269 (23) : 16163-9. |
O'Connor M, Dahlberg AE Mutations at U2555, a tRNA-protected base in 23S rRNA, affect translational fidelity.. Proceedings of the National Academy of Sciences. 1993; 90 (19) : 9214-8. |
Thompson J, Musters W, Cundliffe E, Dahlberg AE Replacement of the L11 binding region within E.coli 23S ribosomal RNA with its homologue from yeast: in vivo and in vitro analysis of hybrid ribosomes altered in the GTPase centre.. EMBO J. 1993; 12 (4) : 1499-504. |
O'Connor M, Göringer HU, Dahlberg AE A ribosomal ambiguity mutation in the 530 loop of E. coli 16S rRNA.. Nucleic acids research. 1992; 20 (16) : 4221-7. |
O'Connor M, De Stasio EA, Dahlberg AE Interaction between 16S ribosomal RNA and ribosomal protein S12: differential effects of paromomycin and streptomycin.. Biochimie. 1991; 73 (12) : 1493-500. |
Göringer HU, Hijazi KA, Murgola EJ, Dahlberg AE Mutations in 16S rRNA that affect UGA (stop codon)-directed translation termination.. Proceedings of the National Academy of Sciences. 1991; 88 (15) : 6603-7. |
Prescott CD, Dahlberg AE A single base change at 726 in 16S rRNA radically alters the pattern of proteins synthesized in vivo.. EMBO J. 1990; 9 (1) : 289-94. |
Tapprich WE, Dahlberg AE A single base mutation at position 2661 in E. coli 23S ribosomal RNA affects the binding of ternary complex to the ribosome.. EMBO J. 1990; 9 (8) : 2649-55. |
De Stasio EA, Dahlberg AE Effects of mutagenesis of a conserved base-paired site near the decoding region of Escherichia coli 16 S ribosomal RNA.. Journal of molecular biology. 1990; 212 (1) : 127-33. |
Frattali AL, Flynn MK, De Stasio EA, Dahlberg AE Effects of mutagenesis of C912 in the streptomycin binding region of Escherichia coli 16S ribosomal RNA.. Biochimica et biophysica acta. 1990; 1050 (1-3) : 27-33. |
Bilgin N, Richter AA, Ehrenberg M, Dahlberg AE, Kurland CG Ribosomal RNA and protein mutants resistant to spectinomycin.. EMBO J. 1990; 9 (3) : 735-9. |
Tapprich WE, Goss DJ, Dahlberg AE Mutation at position 791 in Escherichia coli 16S ribosomal RNA affects processes involved in the initiation of protein synthesis.. Proceedings of the National Academy of Sciences. 1989; 86 (13) : 4927-31. |
De Stasio EA, Moazed D, Noller HF, Dahlberg AE Mutations in 16S ribosomal RNA disrupt antibiotic--RNA interactions.. EMBO J. 1989; 8 (4) : 1213-6. |
Dahlberg AE The functional role of ribosomal RNA in protein synthesis.. Cell. 1989; 57 (4) : 525-9. |
Jemiolo DK, Steen R, Stark MJ, Dahlberg AE Analysis of plasmid-coded ribosomal RNA maxicell techniques.. Methods in enzymology. 1988; 164 : 691-706. |
Murgola EJ, Hijazi KA, Göringer HU, Dahlberg AE Mutant 16S ribosomal RNA: a codon-specific translational suppressor.. Proceedings of the National Academy of Sciences. 1988; 85 (12) : 4162-5. |
Weiss RB, Dunn DM, Dahlberg AE, Atkins JF, Gesteland RF Reading frame switch caused by base-pair formation between the 3' end of 16S rRNA and the mRNA during elongation of protein synthesis in Escherichia coli.. EMBO J. 1988; 7 (5) : 1503-7. |
Thompson J, Cundliffe E, Dahlberg AE Site-directed mutagenesis of Escherichia coli 23 S ribosomal RNA at position 1067 within the GTP hydrolysis centre.. Journal of molecular biology. 1988; 203 (2) : 457-65. |
Jacob WF, Santer M, Dahlberg AE A single base change in the Shine-Dalgarno region of 16S rRNA of Escherichia coli affects translation of many proteins.. Proceedings of the National Academy of Sciences. 1987; 84 (14) : 4757-61. |
Makosky PC, Dahlberg AE Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutants.. Biochimie. 1987; 69 (8) : 885-9. |
Zwieb C, Jemiolo DK, Jacob WF, Wagner R, Dahlberg AE Characterization of a collection of deletion mutants at the 3'-end of 16S ribosomal RNA of Escherichia coli.. Molecular & general genetics : MGG. 1986; 203 (2) : 256-64. |
Steen R, Jemiolo DK, Skinner RH, Dunn JJ, Dahlberg AE Expression of plasmid-coded mutant ribosomal RNA in E. coli: choice of plasmid vectors and gene expression systems.. Progress in nucleic acid research and molecular biology. 1986; 33 : 1-18. |
Steen R, Dahlberg AE, Lade BN, Studier FW, Dunn JJ T7 RNA polymerase directed expression of the Escherichia coli rrnB operon.. EMBO J. 1986; 5 (5) : 1099-103. |
Romero DP, Dahlberg AE The alpha subunit of initiation factor 2 is phosphorylated in vivo in the yeast Saccharomyces cerevisiae.. Molecular and Cellular Biology. 1986; 6 (4) : 1044-9. |
Stark MJ, Gourse RL, Jemiolo DK, Dahlberg AE A mutation in an Escherichia coli ribosomal RNA operon that blocks the production of precursor 23 S ribosomal RNA by RNase III in vivo and in vitro.. Journal of molecular biology. 1985; 182 (2) : 205-16. |
Skinner RH, Stark MJ, Dahlberg AE Mutations within the 23S rRNA coding sequence of E. coli which block ribosome assembly.. EMBO J. 1985; 4 (6) : 1605-8. |
Jemiolo DK, Zwieb C, Dahlberg AE Point mutations in the 3' minor domain of 16S rRNA of E.coli.. Nucleic acids research. 1985; 13 (23) : 8631-43. |
Stark MJ, Gregory RJ, Gourse RL, Thurlow DL, Zwieb C, Zimmermann RA, Dahlberg AE Effects of site-directed mutations in the central domain of 16 S ribosomal RNA upon ribosomal protein binding, RNA processing and 30 S subunit assembly.. Journal of molecular biology. 1984; 178 (2) : 303-22. |
Gregory RJ, Zeller ML, Thurlow DL, Gourse RL, Stark MJ, Dahlberg AE, Zimmermann RA Interaction of ribosomal proteins S6, S8, S15 and S18 with the central domain of 16 S ribosomal RNA from Escherichia coli.. Journal of molecular biology. 1984; 178 (2) : 287-302. |
Göringer HU, Wagner R, Jacob WF, Dahlberg AE, Zwieb C Oligonucleotide directed mutagenesis of Escherichia coli 5S ribosomal RNA: construction of mutant and structural analysis.. Nucleic acids research. 1984; 12 (18) : 6935-50. |
Zwieb C, Dahlberg AE Point mutations in the middle of 16S ribosomal RNA of E. coli produced by deletion loop mutagenesis.. Nucleic acids research. 1984; 12 (10) : 4361-75. |
Zweib C, Dahlberg AE Structural and functional analysis of Escherichia coli ribosomes containing small deletions around position 1760 in the 23S ribosomal RNA.. Nucleic acids research. 1984; 12 (18) : 7135-52. |
Gourse RL, Stark MJ, Dahlberg AE Regions of DNA involved in the stringent control of plasmid-encoded rRNA in vivo.. Cell. 1983; 32 (4) : 1347-54. |
Stark MJ, Gourse RL, Dahlberg AE Site-directed mutagenesis of ribosomal RNA. Analysis of ribosomal RNA deletion mutants using maxicells.. Journal of molecular biology. 1982; 159 (3) : 417-39. |
Gourse RL, Stark MJ, Dahlberg AE Site-directed mutagenesis of ribosomal RNA. Construction and characterization of deletion mutants.. Journal of molecular biology. 1982; 159 (3) : 397-416. |
Helser TL, Baan RA, Dahlberg AE Characterization of a 40S ribosomal subunit complex in polyribosomes of Saccharomyces cerevisiae treated with cycloheximide.. Molecular and Cellular Biology. 1981; 1 (1) : 51-7. |
Tokimatsu H, Strycharz WA, Dahlberg AE Gel electrophoretic studies on ribosomal proteins L7/L12 and the Escherichia coli 50 S subunit.. Journal of molecular biology. 1981; 152 (2) : 397-412. |
Baan RA, Keller PB, Dahlberg AE Isolation of eukaryotic initiation factor 2 from yeast Saccharomyces cerevisiae.. Journal of Biological Chemistry. 1981; 256 (3) : 1063-6. |
Stellwag EJ, Dahlberg AE Electrophoretic transfer of DNA, RNA and protein onto diazobenzyloxymethyl (DBM) - paper.. Nucleic acids research. 1980; 8 (2) : 299-317. |
Dahlberg AE A gel electrophoretic separation of bacterial ribosomal subunits with and without protein S1.. Methods in enzymology. 1979; 59 : 397-401. |
Dahlberg AE, Horodyski F, Keller P Interaction of neomycin with ribosomes and ribosomal ribonucleic acid.. Antimicrobial Agents and Chemotherapy. 1978; 13 (2) : 331-9. |
Dahlberg AE, Dahlberg JE, Lund E, Tokimatsu H, Rabson AB, Calvert PC, Reynolds F, Zahalak M Processing of the 5' end of Escherichia coli 16S ribosomal RNA.. Proceedings of the National Academy of Sciences. 1978; 75 (8) : 3598-602. |
Dahlberg AE, Dahlberg JE Binding of ribosomal protein S1 of Escherichia coli to the 3' end of 16S rRNA.. Proceedings of the National Academy of Sciences. 1975; 72 (8) : 2940-4. |
Morris DR, Dahlberg JE, Dahlberg AE Detection of cation-specific conformational changes in ribosomal RNA by gel electrophoresis.. Nucleic acids research. 1975; 2 (4) : 447-58. |
Morris DR, Dahlberg JE, Dahlberg AE Detection of cation-specific conformational changes in ribosomal RNA by gel electrophoresis.. Nucleic acids research. 1974; 1 (10) : 1249-58. |
Dahlberg AE Two forms of the 30 S ribosomal subunit of Escherichia coli.. Journal of Biological Chemistry. 1974; 249 (23) : 7673-8. |
Dahlberg AE, Lund E, Kjeldgaard NO, Bowman CM, Nomura M Colicin E3 induced cleavage of 16S ribosomal ribonucleic acid; blocking effects of certain antibiotics.. Biochemistry. 1973; 12 (5) : 948-50. |
Dahlberg AE, Lund E, Kjeldgaard NO Some effects of antibiotics on bacterial polyribosomes as studied by gel electrophoresis.. Journal of molecular biology. 1973; 78 (4) : 627-36. |
Dahlberg AE, Peacock AC Studies of 16 and 23 S ribosomal RNA of Escherichia coli using composite gel electrophoresis.. Journal of molecular biology. 1971; 55 (1) : 61-74. |
Lazzarini RA, Dahlberg AE The control of ribonucleic acid synthesis during amino acid deprivation in Escherichia coli.. Journal of Biological Chemistry. 1971; 246 (2) : 420-9. |
Dahlberg AE, Dingman CW, Peacock AC Electrophoretic characterization of bacterial polyribosomes in agarose-acrylamide composite gels.. Journal of molecular biology. 1969; 41 (1) : 139-47. |
NIH GM19756: Polysomes and Subunits: Structure-Function Relationships (9/1/1972 – 3/31/2015)
1: Demirci, H., Gregory, S., Dahlberg, A. and G. Jogl (2007) “Recognition of ribosomal
protein L11 by the protein trimethyltransferase PrmA” . EMBO J. 26, 567-577.
2: Demirci, H., Gregory, S., Dahlberg, A. and G. Jogl (2008) “Multiple-site trimethylation of
ribosomal protein L11 by the PrmA methyltransferase”, Structure,16;1059-1066
3: Brandi, L., Fabbretti, A., Pon, C., Dahlberg, A. and C. Gualerzi (2008) “Initiation of protein
synthesis: A target for antimicrobials”, Expert Opin Ther Targets, 12; 519-534.
4: Rodriguez-Correa, D. and A. Dahlberg (2008) “Kinetic and thermodynamic studies of
peptidyltransferase in ribosomes from the extreme thermophile Thermus thermophilus”.
RNA, 14: 2314-2318.
5: Demirci, H., Gregory, S., Dahlberg, A. and G. Jogl (2008) “Crystal structure of the Thermus
thermophilus 16S rRNA methyltransferase RsmC in complex with cofactor and substrate
guanosine” J. Biol. Chem., 283;26548-26556
6: Gregory ST, Dahlberg AE (2008) Transposition of an insertion sequence, ISTth7, in
the genome of the extreme thermophile Thermus thermophilus HB8. FEMS Microbiol Lett,
289:187-192.
7: Monshupanee T, Gregory ST, Douthwaite S, Chungjatupornchai W, Dahlberg AE
(2008) Mutations in the conserved helix 69 of 23S rRNA of Thermus thermophilus that
affect capreomycin resistance but not posttranscriptional modifications. J Bacteriol,
190:7754-7761.
8: Kapralou S, Fabbretti A, Garulli C, Spurio R, Gualerzi CO, Dahlberg AE, Pon CL (2008)
Translational initiation factor IF1 of Bacillus Sterothermophilus and Thermus thermophilus
substitute for Escherichia coli IF1 in vivo and in vitro without a direct IF1-IF2 interaction.
Molec Microbiol, 70:1368-1377.
9: Gregory ST, Dahlberg AE (2009) Genetic and structural analysis of base substitutions in
the central pseudoknot of Thermus thermophilus 16S ribosomal RNA. RNA,15:215-223.
10: Gregory, S., Carr, J. and A. Dahlberg (2009) A signal relay between ribosomal protein
S12 and elongation factor Tu during decoding of mRNA, RNA; 15:208-214.
11: Demirci, H., Belardinelli, R., Seri, E., Gregory, S.T., Gualerzi, C., Dahlberg, A.E. & Jogl
G. (2009) Structural rearrangements in the active site of the Thermus thermophilus 16S
rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine. J. Mol.
Biol. 388, 271- 282.
12: Gregory, S.T., Demirci, H., Belardinelli, R., Monshupanee, T., Gualerzi, C., Dahlberg,
A.E. & Jogl G. (2009) Structural and functional studies of the Thermus thermophilus 16S
rRNA methyltransferase RsmG. RNA 15, 1693-704.
13: Demirci, H., Murphy, F., Belardinelli, R., Kelley, A., Ramakrishnan, V., Gregory, S.,
Dahlberg, A., & Jogl,G. (2010) Modification of 16S ribosomal RNA by the KsgA
methyltransferase restructures the 30S subunit to optimize ribosome function. RNA 16,
2319-2324.
14: Monshupanee T, Johansen SK, Dahlberg AE, Douthwaite S (2012) Capreomycin
Susceptibility is increased by TlyA-directed 2’-O-methylation on both ribosomes subunits.
Mol.Microbiol. 85(6), 1194-1203.
15: Demirci H, Murphy IV F, Murphy E, Gregory ST, Dahlberg AE, Jogl G. (2013) A structural
basis for streptomycin-induced misreading of the genetic code. Nat. Commun.4:1355
doi:10.1038/ncomms2346, PMC3552334/.
16: Demirci H, Sierra R, Laksmono H, Shoeman R, Botha S, Barends T, Nass K, Schlichting I,
Doak B, Gati C, Williams G, Boutet S, Messerschmidt M, Jogl G, Dahlberg A, Gregory S,
Bogan M (2013) Serial femtosecond X-ray diffraction of 30S ribosomal subunit microcrystals
in liquid suspension at ambient temperature using an X-ray free-electron laser. ActaCryst.F69
[doi:10.1107/S174430911302099X]
17: Demirci H, Wang L, Murphy F, Murphy E, Carr J, Blanchard S, Jogl G, Dahlberg A, Gregory S
(2013) The central role of protein S12 in organizing the structure of the decoding site of the
ribosome. RNA 19, 1791-1801.
Year | Degree | Institution |
---|---|---|
1968 | PhD | University of Chicago |
1965 | MD | University of Chicago |
1960 | BS | Haverford College |
Name | Title |
---|---|
Gregory, Steven | Associate Professor of Medical Science (Research) |
Jogl, Gerwald | Associate Professor of Biology |
1. American Society for Biochemistry and Molecular Biology
2. American Association for the Advancement of Science
3. American Society for Microbiology