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David R. Strong Adjunct Assistant Professor of Psychiatry and Human Behavior

Brown Affiliations

scholarly work

McBride, O., Strong, D. R., & Kahler, C. W. (in press). Exploring the stability of a nicotine dependence continuum over time: Findings from the longitudinal National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Nicotine and Tobacco Research.

Cohn, A., Strong, D. R., Abrantes, A., & Brown, R. A. (in press). History of single episode and recurrent major depressive disorder among smokers in cessation treatment: Associations with depressive symptomatology and early cessation failure. Addictive Disorders and Their Treatment.

Abrantes, A. M., Lee, C.S., MacPherson, L., Strong, D. R., Borrelli, B., & Brown, R. A. (in press). Youth risk behavior correlates of quit attempts and cessation among adolescent smokers. Journal of Behavioral Medicine, 32, 142-149.

Uebelacker, L, Weisberg, R. Smith, M., Strong, D.R., Miller, I. W. (in press) Time invariant and time-varying predictors of depression symptoms in primary care patients. The Primary Care Companion.

MacPherson, L.M., Lejuez, C. W., Kahler, C.W., Zvolensky. M., Hopko, D., Brown, R. A., Strong, D. R., Tull, M., Matusiewicz, A., & Rodman, D. (in press). Randomized Controlled Trial of Behavioral Activation Smoking Cessation Treatment for Smokers with Elevated Depressive Symptoms, Journal of Consulting and Clinical Psychology.

Kahler, C.W., Spillane, N.S., Leventhal, A.M., Strong, D.R., Brown, R.A., and Monti, P.M. (2009). Hostility and smoking cessation treatment outcome in heavy social drinkers. Psychology of Addictive Behaviors, 23, 67-76.

Stuart, G.L., O'Farrell, T.J., Leonard, K., Moore, T.M., Temple, J.R., Ramsey, S.E., Stout, R., Kahler, C., Bucossi, M., Andersen, S., Recupero, P., Walsh, Z., Chatav Schonbrun, Y., Strong, D., Rothman, E., Rhatigan, D., & Monti, P. (2009). Examining the interface between substance misuse and intimate partner violence. Substance Abuse: Research and Treatment, 3 25-29.

Weinstock, L., Strong, D.R., Uebelacker, L. Miller, I.W. (2009). Differential item functioning of DSM-IV depressive symptoms in individuals with a history of mania versus those without: An item response theory analysis. Bipolar Disorders, 11, 289-297.

Abrantes, A.M., Strong, D. R., Cohn, A., Cameron, A. Y., Greenberg, B. D., Mancebo, M. C., & Brown, R. A. (2009) Acute changes in obsessions and compulsions following moderate-intensity aerobic exercise among patients with obsessive-compulsive disorder. Journal of Anxiety Disorders, 23, 923-927.

Strong, D.R., Kahler, C.W., Colby, S. M., Griesler, P.G., & Kandel, D. (2009). Linking measures of adolescent nicotine dependence to a common latent continuum. Drug and Alcohol Dependence, 99, 296-308.

Zvolensky, M. J., Strong, D. R., Bernstein, A., Vujanovic, A. A., & Marshall, E. C. (2009). Evaluation of Anxiety Sensitivity among Daily Adult Smokers using Item Response Theory Analysis. Journal of Anxiety Disorders, 23, 230-239.

Palm, K.M., Abrantes, A.M., Strong, D.R., Ramsey, S.E., & Brown, R.A. (2009). Smoking characteristics of adolescent smokers with posttraumatic stress disorder in an inpatient hospital setting. Journal of Dual Diagnosis, 5, 14-29.

Brown, R. A., Lejuez, C. W., Strong, D. R., Kahler, C. W., Zvolensky, M. J. Carpenter, L., Niaura, R., & Price, L. (2009). A prospective examination of distress tolerance and early smoking lapse in self-quitters. Nicotine and Tobacco Research, 11, 493-502.

Brown, R.A., Abrantes, A.M., Read, J.P., Marcus, B.H., Jakicic, J., Strong, D.R., Oakley, J.R., Ramsey, S.E., Kahler, C.W., Stuart, G.G., Dubreil, M.E., & Gordon, A.A. (2009). Aerobic exercise for alcohol recovery: Rationale, program description, and preliminary findings. Behavior Modification, 33, 220-249.

Palm, K. P., Strong, D. R., MacPherson, L. M. (2009). Evaluating Symptom Expression as a Function of a Posttraumatic Stress Disorder Severity. Journal of Anxiety Disorders, 23, 27-37.

Uebelacker, L. A., Strong, D. R., Weinstock, L. M., and Miler, I. W. (2009). Use of item response theory to understand differential functioning of DSM-IV major depression symptoms by race, ethnicity, and gender. Psychological Medicine, 39, 591-601.

Strong, D. R., Kahler, C. W., Leventhal, A. M., Abrantes, A. M., Lloyd-Richardson, E., Niaura, R. & Brown, R.A. (2009). Impact of Bupropion and CBT for Depression on Positive Affect, Negative Affect and Urges to Smoke During Cessation Treatment. Nicotine and Tobacco Research, 11, 1142-1153.

Brown, R. A., Strong, D. R., Abrantes, A., Kahler, C. W., Ramsey, S. E., & Myers, M. G. (2009). Motivational Interviewing affects substance use outcomes among teens with psychopathology. Addictive Behaviors, 34, 887-891.

Abrantes, A.M., Strong, D.R., Lejuez, C.W., Kahler, C.W., Carpenter, L.L., Price, L.H, Niaura, R., & Brown, R.A. (2008). The role of negative affect in risk for early lapse among low distress tolerance smokers. Addictive Behaviors, 33, 1394-1401.

MacPherson, L. M., Strong, D.R. & Myers, M. G. (2008) Using an item response model to examine the nicotine dependence construct as characterized by the HONC and the mFTQ among adolescent smokers. Addictive Behaviors, 33, 880-894.

Kahler, C.W., Hustad, J., Barnett, N.P., Strong, D.R, & Borsari, B. (2008). Validation of the 30-day version of the Brief Young Adult Alcohol Consequences Questionnaire for use in longitudinal studies. Journal of Studies on Alcohol and Drugs, 69, 611-615

Kahler, C.W., Strong, D. R., Papandonatos, G.D., Colby, S.M., Clark, M.A., Boergers, J., Niaura, R., Abrams, D.B., & Buka, S.L. (2008). Cigarette smoking and the lifetime alcohol involvement continuum. Drug and Alcohol Dependence, 93, 111-120.

Kahler, C.W., LaChance, H.R., Strong, D.R., Ramsey, S.E., Monti, P.M., & Brown, R.A. (2007). The commitment to quitting smoking scale: Initial validation in a smoking cessation trial for heavy social drinkers. Addictive Behaviors, 32, 2420-2424.

Read, J. P., Merrill, J., Kahler, C. W., & Strong, D.R. (2007). Predicting functional outcomes among college drinkers: Reliability and predictive validity of the Young Adult Alcohol Consequences Questionnaire. Addictive Behaviors, 32, 2597-2610.

David, S. P., Strong, D. R., Munafo, M., Brown, R, A, Lloyd-Richardson, E.E. , Wileyto, P. A., Evins, E., Shields, P. G., Lerman, C., Niaura, R. (2007). Bupropion efficacy for smoking cessation is influenced by the DRD2 Taq1A polymorphism: Analysis of pooled data from two clinical trials. Nicotine and Tobacco Research, 9, 1251-1257.

Brown, R. A., Niaura, R., Llyod-Richardson, E., Strong, D. R., Kahler, C. W., Abrantes, A. M., & Miller, I. W. (2007). Bupropion and cognitive behavioral treatment for depression in smoking cessation. Nicotine and Tobacco Research, 9, 721-730.

Brown, R.A., Palm, K. M., Strong, D. R., Lejuez, C.W., Kahler, C. W., Zvolensky, M. J. et al. (2007). Distress tolerance treatment for early lapse smokers: Rationale, program description, and preliminary findings. Behavior Modification, 25, 713-733.

Abrantes, A., Palm, K., Strong, D. R., Ramsey, S. E., & Brown, R. A. (2007) Treatment Utilization after Psychiatric Inpatient Hospitalization among Adolescents with and without Substance Use Disorders. Addictive Disorders and Their Treatment, 6, 147-156.

Brown, R.A., Abrantes, A., Strong, D. R., Mancebo, M. C., Menard, J., Rasmussen, S. A., Greenberg, B. D. (2007). A pilot study of moderate-intensity aerobic exercise for obsessive compulsive disorder. Journal of Nervous and Mental Disease, 195, 514-520.

David, S. P., Brown, R. A., Papandonatos, G. D., Lloyd-Richardson, E. E., Munafo, M. R., Shields, P. G., Lerman, C., Strong, D. R., McCaffery, J., & Niaura, R. (2007). Pharmacogenomic clinical trial of sustained-release bupropion for smoking cessation, Nicotine and Tobacco Research, 9, 821-833.

Strong, D. R. & Kahler, C. W. (2007) Evaluation of the continuum of gambling problem severity using the DSM-IV. Addiction, 102, 713-721.

Strong, D. R., Kahler, C. W., Myers, M. G., Abrantes, A. M., MacPherson, L., Ramsey, S. E. & Brown, R. A. (2007). Nicotine dependence symptoms among adolescents with psychiatric disorders: Using a Rasch model to evaluate symptom expression across time. Nicotine & Tobacco Research, 9, 557-569.

Beevers, C., Strong, D. R., Meyer, B., Pilkonis, P. A., & Miller, I. W. (2007). Efficiently assessing negative cognition in depression: An Item Response Theory analysis of the Dysfunctional Attitudes Scale. Psychological Assessment, 19, 199-209.

Appodaca, T., Abrantes, A., Strong, D. R., Ramsey, S. E., & Brown, R. A. (2007) Motivational factors and smoking readiness among teens with psychiatric comorbidity. Addictive Behaviors, 32, 1119-1130.

Roberson-Nay, R., Strong, D. R., Nay, W. T., Beidel, D. & Turner, S. (2007). Development of an abbreviated Social Phobia and Anxiety Inventory (SPAI) using item response theory. Psychological Assessment, 19, 133-145.

Palm, K. & Strong, D. R. (2007). Item response analysis of the WBSI in college women. Personality and Individual Differences, 42, 87-98.

MacPherson, L., Strong, D.R., Kahler, C.W., Abrantes, A.M., Ramsey, S.E., & Brown, R.A. (2007). Post treatment change in smoking and its association with future smoking and cessation efforts among adolescents with psychiatric comorbidity. Nicotine and Tobacco Research, 9, 1297-1307

research overview

David Strong collaborates in the development of smoking cessation interventions among adolescent and adult smokers with psychiatric risk factors and also does biobehavioral research on stress and smoking cessation. He has collaborated on several psychometric studies of clinical assessment instruments and has applied methods based in item response theory to faciliatate understanding of psychological constructs used to study addictions.

research statement

David Strong is an associate professor (research) of psychiatry in the Brown Medical School and a research psychologist within the Addictions Research Group at Butler Hospital. In addition to collaborating in the development of smoking cessation interventions among adolescent and adult smokers with affective vulnerability and biobehavioral research of stress and smoking cessation, he has pursued rigorous psychometric evaluation of clinical assessment instruments to aid both in the precision of measurement and conceptual clarity of key latent constructs in the study of addictions. Recent collaborations within the Brown Medical School have generated manuscripts describing the utility of using taxometrics and item response models to examine the psychometric properties of existing clinical measures of nicotine dependence, nicotine withdrawal, alcohol problems, affective vulnerability, and problem gambling.

funded research

Research Therapist/Co-Investigator. Smoking cessation in teens with comorbid psychopathology. National Cancer Institute. Grant # 1R01CA-77082, $1,847,469. Funded 1997 - 2001.
Research Therapist/Co-Investigator. Coping with depression in smoking cessation. National Institute on Drug Abuse. Grant # 2R01DA-08511, $1,983,952. (Second competitive renewal of Coping with depression in smoking cessation), Funded: 1992 - 1996; 1997 - 2001.
Project Director/Co-Investigator. Behavioral vulnerability to early smoking lapse. National Cancer Institute. Grant #1R21CA88297, $362,500 over two years. Funded 2000 - 2002.
Co-Investigator. Applying Exercise Intervention to Drug Treatment. National Institute on Drug Abuse. Grant # 1 R01DA14599-01, $826,072; Funded: 2002 – 2004.
Co-Investigator. Development of an Exercise Intervention for Alcoholics. National Institute on Alcohol Abuse and Alcoholism. Grant # 1 R01AA13418-01, $618,696; Funded 2002 – 2004.
Co-Investigator. Improving Smoking Cessation in Smokers with Depressive Symptoms. American Cancer Society. Grant # RSGPB PBP-103382, $1,355,000; Funded: 2002- 2006.
Co-Investigator. Distress Tolerance Treatment for Early Smoking Lapsers. National Institute on Drug Abuse. Grant #1 R01DA017332. $1,095,000 Funded: 9/30/03-11/30/06
Co-Investigator. MI for Teen Substance Abuse with Psychiatric Comorbidity. National Institute on Drug Abuse Grant # 1 R01DA016738-01 A1. $2,514,565; Funded: 04/01/04 – 03/31/09
Co-Investigator: DEX/CRH Response: Mood/Anxiety Disorder Endophenotype? Grant # 1 R01MH068767-01 $1,000,000; Funded: 04/01/04 – 03/31/08
Principal Investigator. Mood Management Phone Counseling in Smoking Cessation. National Institute on Drug Abuse, Grant # 1 R01DA017947-01. $985,550; Funded: 05/20/05 – 4/30/09
Co-Investigator Family Check-Up for Depression Prevention. National Institute of Mental Health Grant # R34MH070743, $450,000; Funded: 04/01/05- 03/31/08
Co-Investigator: Treatment Seeking for Depression Among Pregnant Women. National Institute of Mental Health Grant# 1 R34MH079108-01. Funded: 08/13/07 - 06/30/10. $410,235
Co-Investigator: Sequential Use of Fluoxetine for Smokers with Elevated Depressive Symptoms National Institute on Drug Abuse Grant # 1 R01DA023190-01 Funded: 9/28/07-6/30/11, $2,093,005
Co-Investigator: Development of a Treatment Adherence Program for Bipolar Substance Abusers. National Institute on Drug Abuse Grant # 1 R01R01DA02307 Funded: 9/30/07-7/31/10, $675,000
Co-Investigator: Brief Intervention to Reduce Drinking among Batterers. National Institute of Alcohol Abuse and Alcoholism. Grant # R01AA014193-05. Funded: 7/1/03 – 6/30/09.
Co-Investigator: Brief Intervention to reduce drinking and intimate partner violence in women. National Institute of Alcohol Abuse and Alcoholism Grant # R01AA016315-02, Funded: 5/1/07 – 8/2/08.
Co-Investigator: Development of a Home-Based Family Treatment for Postpartum Depression. National Institute of Mental Health. Grant # 1R34MH083065-01. Funded: 7/1/08-4/30/11.
Principal Investigator: Motivating Cessation Treatment Engagement in Depressed Inpatient Smokers. American Cancer Society Grant # RSGPB-08-145-01-CPPB, Funded: 7/01/08-6/30/11, $720,000.
Co-Investigator: Postpartum sleep effects on smoking relapse. National Institute on Drug Abuse. Grant # 1R21DA026448–01. Funded: 2009-2011, $406,643.
Co-Investigator: Neurocircuitry Underlying DBS Effects in OCD: A Window into Mechanisms of Action. Core C: Informatics. Grant # 1 P50 MH086400-01 Funded: 7/1/09 - 6/30/14. $9,312,158.