Jean Marie Daley Assistant Professor of Medicine (Research)

Dr. Jean Daley is a graduate of Bowdoin College and Tufts University School of Medicine. She completed a residency in General Surgery and a Research Fellowship in Surgery at Brown University and Rhode Island Hospital. She is presently Assistant Professor of Surgery (Research). Her research focuses on the phenotypic and functional characteristics of macrophages in a mouse model of tissue injury.

Brown Affiliations

research overview

Dr. Daley studies the cellular events that follow injury. Her research focuses on the characteristics and functions of macrophages that accumulate at the site of tissue injury. These macrophages are essential to the repair process.

research statement

Laboratory studies focus on the phenotypic and functional profiles of wound macrophages. We have described temporal changes in populations of wound macrophages at the site of tissue injury, and have demonstrated that changes in wound macrophage populations are independent of IL-4 and IL-13. Ongoing studies focus on the heterogeneity of macrophage populations in the wound, including the origins and functional consequences of macrophage diversity in the wound environment.

funded research

Current funding:
1. "Heterogeneity of wound macrophages", Principal Investigator
Principal Investigator: Jean M. Daley, MD
Grant #K08GM79227 NIH
Total Costs: $607,365
April 1, 2007 – March 31, 2012

2. "Trauma and Inflammation Research Training", Associate Faculty
Principal Investigator: Jorge E. Albina, MD
Grant# T32GM65085
Total Costs: $170,334
July 1, 2009 - June 30, 2014

Previous funding:
1. "Cellular/molecular biology of inflammation and repair", Co-investigator
Principal Investigator: Jorge E. Albina, MD
Grant #R01GM 42859, NIH
Total Costs: $1,324,400
March 1, 2006 through March 31, 2007

2. "Phenotypic Characterization of Wound Neutrophils", Principal Investigator
Principal Investigator: Jean M. Daley, MD
Grant #20050238, Rhode Island Foundation
Amount: $10,000
January 1, 2005 through December 31, 2005

3. "Supplement to Promote Reentry into Biomedical and Behavioral Research Careers", Investigator
Principal Investigator: Jorge E. Albina, MD
Supplement to Grant # RO1GM 42859, NIH
Total Costs: $315,364
June 1, 2002 through February 28, 2006