Jane L. Eisen Adjunct Professor of Psychiatry and Human Behavior

Dr. Eisen is an Associate Professor in the Department of Psychiatry and Human Behavior at Brown University. Her training includes an M.D. degree from the New York University School of Medicine followed by a residency in Psychiatry at Mt. Sinai Hospital in New York. She began working in the Obsessive-Compulsive Disorder (OCD) Clinic at Butler Hospital under the mentorship of Dr. Steven Rasmussen and has developed both clinical and research expertise in this disorder, particularly in the area of psychopathology. Dr. Eisen is currently funded by the NIMH to study course of illness in OCD, and has been involved in numerous treatment studies of OCD.
In addition to her research and clinical involvement in OCD, Dr. Eisen has had a longstanding interest in education and teaching, and has been actively involved in teaching and supervision throughout her career. In 1996, she was appointed Associate Training Director of the Brown Psychiatry Residency and Director of the Core Clerkship in Psychiatry for Brown Medical School. Dr. Eisen is currently Training Director of the Brown Psychiatry Residency, having been appointed in 2003. She continues to be involved with medical student education overseeing students' elective experiences, coordinating their longitudinal electives in Psychiatry and working with 3rd and 4th students who have decided to pursue careers in Psychiatry as their advisor. Additional roles in the Department of Psychiatry and Human Behavior including chairing the Educational Committee, as a member of the Psychiatry Management Advisory Committee, (an executive committee dealing with issues of training, research infrastructure, faculty recruitment, and promotion) and as the Co-Training Director for the Combined Neurology Psychiatry Residency.

Brown Affiliations

Research Areas

scholarly work

Eisen, J.L., Mancebo, M.C., Pinto, A., Coles, M.E., Pagano, M. E., Stout, R.L., Rasmussen, S.A (in press): Impact of obsessive-compulsive disorder on quality of life. Comprehensive Psychiatry

Pinto, A., Mancebo, M. C., Eisen, J. L., Pagano, M. E., & Rasmussen, S. The Brown Longitudinal Obsessive Compulsive Study: Clinical features and symptoms. (in press).The Journal of Clinical Psychiatry

Grant, J.E. Mancebo, M.C. Pinto, A., Eisen, J.L., Rasmussen, S.A. Impulse Control Disorders in Adults with Obsessive Compulsive Disorder. (in press.) Journal of Psychiatric Research

Kaplan, G.B., Phillips, K.A., Vaccaro, A., Eisen, J,L,, Posternak, M,, MacAskil, H,S, Assessment of Insight into Delusional Beliefs in Schizophrenia Using the Brown Assessment of Beliefs Scale. (in press). Letter to the Editor, Schizophrenia Research

Mancebo, M.C., Eisen, J.L., Grant, J.E,, Rasmussen, S.A.:Obsessive Compulsive Personality Disorder and Obsessive Compulsive Disorder: Clinical Characteristics, Diagnostic Difficulties, and Treatment. (in press). Annals of Clinical Psychiatry.

Eisen, J.L., Coles, M.E., Shea, M.T., Pagano, M.E., Stout, R.L., Yen, S., Grilo, C.M., Rasmussen, S.A. Clarifying the convergence between obsessive compulsive personality disorder criteria and obsessive compulsive disorder. (in press). Journal of Personality Disorders.

Eisen, JL, Phillips, KA, Coles, ME, Rasmussen, SA: Insight in Obsessive Compulsive Disorder and Body Dysmorphic Disorder. Comprehensive Psychiatry. 2004;45(1):10-15.

Eisen, JL, Leonard HL, Swedo SE, Price LH, Zabriskie JB, Chiang SY, Karitani M, Rasmussen: The Use of Antibody D8/17 to Identify B Cells in Adults with Obsessive Compulsive Disorder. Psychiatry Research. 2001;104:221-225.

Phillips KA, McElroy SL, Dwight MM, Eisen JL, Rasmussen SA: Delusionality and Response to Open-Label Fluvoxamine in Body Dysmorphic Disorder. Journal of Clinical Psychiatry. 2001; Feb:62(2):87-91.

Steketee G, Eisen JL, Dyke I, Warshaw, Rasmussen SA: Predictors of Course in Obsessive Compulsive Disorder. Psychiatry Research, 89 (1999) 229-238.

Eisen, JL, Goodman W, Keller MB, Warshaw M, DeMarco L, Luce, DD, Rasmussen, SA. Patterns of Remission and Relapse in OCD: A 2-year Prospective Study, Journal of Clinical Psychiatry. 1999; 60:346-351.

Eisen, JL, Phillips, KA, Beer, DA, Atala, KD, Rasmussen, SA. The Brown Assessment of Beliefs Scale: Reliability and Validity. American Journal of Psychiatry. 1998; 155:102-108.

research overview

Jane Eisen's current research focuses on the symptoms, treatment, and outcome of Obsessive Compulsive Disorder (OCD), a common and, at times, debilitating anxiety disorder. She is involved in a 10-year prospective study of OCD involving 300 adults and 100 children. This project is focused on examining factors impacting course and treatment response in OCD. In addition, she is investigating the relationship between OCD and other psychiatric disorders as well as the role of insight in OCD.

research statement

Jane Eisen has been involved in clinical research regarding the phenonemonology, course, and treatment of Obsessive Compulsive Disorder. She has been co-principal investigator in a number of multi-center pharmacological efficacy trials of the serotonin reuptake inhibitors (SRIs) in OCD and has participated in several SRI relapse prevention studies in OCD. She is currently the co-principal investigator of a federally funded 10-year prospective longitudinal study of OCD (Steven Rasmussen, PI), and has been a consultant for the federally funded longitudinal study of anxiety disorders headed by Dr. Keller (Harvard Anxiety Disorders Program).

funded research

Longitudinal Follow-up Study of Obsessive Compulsive Disorder. National Institute of Mental Health (NIMH).
Co-Investigator (S. Rasmussen, PI), (MH60218-01A1 ).
The broad objective of this project is to develop a comprehensive picture of the longitudinal course and outcome of obsessive compulsive disorder using a longitudinal, observational design to follow 400 subjects including children and adults with Obsessive Compulsive Disorder (OCD) prospectively. The aims are to identify patterns of course of OCD and predictors of course, to describe treatments received and reasons for lack of treatment, and to assess the relationship between psychosocial functioning, quality of life and OC symptom severity. The grant was originally funded for five years and has received another five years of funding.