Dr. Jack Wands is the Jeffrey and Kimberly Greenberg-Artemis and Martha Joukowsky Professor in Gastroenterology, and Professor of Medical Science, Brown Medical School. He founded and developed the Rhode Island Hospital/Brown University Liver Research Center. Dr. Wands received his M.D. with High Honors from the University of Washington School of Medicine. He completed a four-year Fellowship in Internal Medicine at Johns Hopkins, and was Chief Resident in Medicine at Johns Hopkins/Bayview Medical Center (formerly Baltimore City Hospital). A Clinical and Research Fellowship in Gastroenterology were performed at Massachusetts General Hospital. Dr. Wands is an internationally renowned physician/scientist who has received a number of awards including two N.I.H. merit awards, Max Planck Merit Award, and a Bristol Myers Squibb unrestricted grant in infectious disease. He is the recipient of 204 U.S. and international patents related to investigative work in hepatology. He is the recipient of several major N.I.H. grants and has published over 400 peer-reviewed manuscripts and has contributed to 56 textbooks.
| Bai X, Zhou Y, Yokota Y, Matsumoto Y, Zhai B, Maarouf N, Hayashi H, Carlson R, Zhang S, Sousa A, Sun B, Ghanbari H, Dong X, Wands JR. "Adaptive antitumor immune response stimulated by bio-nanoparticle based vaccine and checkpoint blockade." Journal of experimental & clinical cancer research : CR, vol. 41, no. 1, 2022, pp. 132. |
| Chung W, Rich H, Wands J. "A Predictive Model for the Diagnostic and Therapeutic Yield of Colonoscopy Performed for Lower Gastrointestinal Bleeding." Journal of clinical gastroenterology, vol. 56, no. 2, 2021, pp. 154-160. |
| Bai X, Zhou Y, Lin Q, Huang CK, Zhang S, Carlson RI, Ghanbari H, Sun B, Wands JR, Dong X. "Bio-nanoparticle based therapeutic vaccine induces immunogenic response against triple negative breast cancer." American journal of cancer research, vol. 11, no. 9, 2021, pp. 4141-4174. |
| Lin Q, Chen X, Meng F, Ogawa K, Li M, Song R, Zhang S, Zhang Z, Kong X, Xu Q, He F, Liu D, Bai X, Sun B, Hung MC, Liu L, Wands JR, Dong X. "Multi-organ metastasis as destination for breast cancer cells guided by biomechanical architecture." American journal of cancer research, vol. 11, no. 6, 2021, pp. 2537-2567. |
| Zhang S, Sousa A, Lin M, Iwano A, Jain R, Ma B, Lee CM, Park JW, Kamle S, Carlson R, Lee GG, Elias JA, Wands JR. "Role of Chitinase 3-like 1 protein in the pathogenesis of hepatic insulin resistance in nonalcoholic steatohepatitis." Cells, vol. 10, no. 2, 2021, pp. 201. |
| Bai X, Zhang H, Zhou Y, Nagaoka K, Meng J, Ji C, Liu D, Dong X, Cao K, Mulla J, Cheng Z, Mueller W, Bay A, Hildebrand G, Lu S, Wallace J, Wands JR, Sun B, Huang CK. "Ten-Eleven Translocation 1 Promotes Malignant Progression of Cholangiocarcinoma With Wild-Type Isocitrate Dehydrogenase 1." Hepatology, vol. 73, no. 5, 2021, pp. 1747-1763. |
| Chung W, Promrat K, Wands J. "Clinical implications, diagnosis, and management of diabetes in patients with chronic liver diseases." World journal of hepatology, vol. 12, no. 9, 2020, pp. 533-557. |
| Ogawa K, Lin Q, Li L, Bai X, Chen X, Chen H, Kong R, Wang Y, Zhu H, He F, Xu Q, Liu L, Li M, Zhang S, Nagaoka K, Carlson R, Safran H, Charpentier K, Sun B, Wands J, Dong X. "Prometastatic secretome trafficking via exosomes initiates pancreatic cancer pulmonary metastasis." Cancer Letters, vol. 481, 2020, pp. 63-75. |
| Nagaoka K, Ogawa K, Ji C, Cao KY, Bai X, Mulla J, Cheng Z, Wands JR, Huang CK. "Targeting Aspartate Beta-Hydroxylase with the Small Molecule Inhibitor MO-I-1182 Suppresses Cholangiocarcinoma Metastasis." Digestive Diseases and Sciences, vol. 66, no. 4, 2020, pp. 1080-1089. |
| Tomimaru, Yoshito, Aihara, Arihiro, Wands, Jack R., Aloman, Costica, Kim, Miran. "A Novel Drug, CC-122, Inhibits Tumor Growth in Hepatocellular Carcinoma through Downregulation of an Oncogenic TCF-4 Isoform." Translational Oncology, vol. 12, no. 10, 2019, pp. 1345-1356. |
| Nagaoka K, Bai X, Ogawa K, Dong X, Zhang S, Zhou Y, Carlson RI, Jiang Z-G, Fuller S, Lebowitz MS, Ghanbari H, Wands JR. "Anti-tumor activity of antibody drug conjugate targeting aspartate-β-hydroxylase in pancreatic ductal adenocarcinoma." Cancer Letters, vol. 449, 2019, pp. 87-98. |
| 15. Ogawa K, Lin Q, Li L, Bai X, Chen X, Chen H, Kong R, Wang Y, Zhu H, He F, Xu Q, Liu L, Li M, Zhang S, Nagaoka K, Carlson R, Safran H, Charpentier K, Sun B, Wands J, Dong X. "Aspartate β-hydroxylase promotes pancreatic ductal adenocarcinoma metastasis through activation of SRC signaling pathway." Journal of hematology & oncology, vol. 12, no. 1, 2019, pp. 144. |
| Lin Q, Chen X, Meng F, Ogawa K, Li M, Song R, Zhang S, Zhang Z, Kong X, Xu Q, He F, Bai X, Sun B, Hung MC, Liu L, Wands J, Dong X. "ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis." Molecular cancer, vol. 18, no. 1, 2019, pp. 156. |
| Ji C, Nagaoka K, Zou J, Casulli S, Lu S, Cao KY, Zhang H, Iwagami Y, Carlson RI, Brooks K, Lawrence J, Mueller W, Wands JR, Huang CK. "Chronic ethanol-mediated hepatocyte apoptosis links to decreased TET1 and 5-hydroxymethylcytosine formation." The FASEB Journal, vol. 33, no. 2, 2019, pp. fj201800736R. |
| Shimada S, Mogushi K, Akiyama Y, Furuyama T, Watanabe S, Ogura T, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Arii S, Tanabe M, Wands JR, Tanaka S. "Comprehensive molecular and immunological characterization of hepatocellular carcinoma." EBioMedicine, vol. 40, 2019, pp. 457-470. |
| Dong X, Lin Q, Aihara A, Li Y, Huang CK, Chung W, Tang Q, Chen X, Carlson R, Nadolny C, Gabriel G, Olsen M, Wands JR. "Correction: Aspartate β-hydroxylase expression promotes a malignant pancreatic cellular phenotype." Oncotarget, vol. 10, no. 61, 2019, pp. 6644-6646. |
| Huang CK, Iwagami Y, Zou J, Casulli S, Lu S, Nagaoka K, Ji C, Ogawa K, Cao KY, Gao JS, Carlson RI, Wands JR. "Aspartate beta-hydroxylase promotes cholangiocarcinoma progression by modulating RB1 phosphorylation." Cancer Letters, vol. 429, 2018, pp. 1-10. |
| de la Monte SM, Tong M, Wands JR. "The 20-Year Voyage Aboard the Journal of Alzheimer's Disease: Docking at 'Type 3 Diabetes', Environmental/Exposure Factors, Pathogenic Mechanisms, and Potential Treatments." Journal of Alzheimer's disease : JAD, vol. 62, no. 3, 2018, pp. 1381-1390. |
| Kwei, Karen, Tang, Xiaoli, Lok, Anna S., Sureau, Camille, Garcia, Tamako, Li, Jisu, Wands, Jack, Tong, Shuping. "Correction for Kwei et al., “Impaired Virion Secretion by Hepatitis B Virus Immune Escape Mutants and Its Rescue by Wild-Type Envelope Proteins or a Second-Site Mutation”." Journal of Virology, vol. 91, no. 24, 2017, pp. e01655-17. |
| Zong L, Qin Y, Jia H, Ye L, Wang Y, Zhang J, Wands JR, Tong S, Li J. "Differential regulation of hepatitis B virus core protein expression and genome replication by a small upstream open reading frame and naturally occurring mutations in the precore region." Virology, vol. 505, 2017, pp. 155-161. |
| Shimoda M, Hori A, Wands JR, Tsunashima R, Naoi Y, Miyake T, Tanei T, Kagara N, Shimazu K, Kim SJ, Noguchi S. "Endocrine sensitivity of estrogen receptor-positive breast cancer is negatively correlated with aspartate-β-hydroxylase expression." Cancer science, vol. 108, no. 12, 2017, pp. 2454-2461. |
| Iwagami Y, Casulli S, Nagaoka K, Kim M, Carlson RI, Ogawa K, Lebowitz MS, Fuller S, Biswas B, Stewart S, Dong X, Ghanbari H, Wands JR. "Lambda phage-based vaccine induces antitumor immunity in hepatocellular carcinoma." Heliyon, vol. 3, no. 9, 2017, pp. e00407. |
| Zhou H, Gewaily D, Ahn SH, Preskill C, Wang Y, Zong L, Zhang J, Han KH, Wands J, Li J, Tong S. "Sequence analysis and functional characterization of full-length hepatitis B virus genomes from Korean cirrhotic patients with or without liver cancer." Virus research, vol. 235, 2017, pp. 86-95. |
| Chung W, Kim M, de la Monte S, Longato L, Carlson R, Slagle BL, Dong X, Wands JR. "Activation of signal transduction pathways during hepatic oncogenesis." Cancer Letters, vol. 370, no. 1, 2016, pp. 1-9. |
| Chung, Waihong, Kim, Miran, de la Monte, Suzanne, Longato, Lisa, Carlson, Rolf, Slagle, Betty L., Dong, Xiaoqun, Wands, Jack R. "Activation of signal transduction pathways during hepatic oncogenesis." Cancer Letters, vol. 370, no. 1, 2016, pp. 1-9. |
| Huang CK, Iwagami Y, Aihara A, Chung W, de la Monte S, Thomas JM, Olsen M, Carlson R, Yu T, Dong X, Wands J. "Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression." PLoS ONE, vol. 11, no. 3, 2016, pp. e0150336. |
| Iwagami Y, Huang CK, Olsen MJ, Thomas JM, Jang G, Kim M, Lin Q, Carlson RI, Wagner CE, Dong X, Wands JR. "Aspartate β-hydroxylase modulates cellular senescence through glycogen synthase kinase 3β in hepatocellular carcinoma." Hepatology, vol. 63, no. 4, 2016, pp. 1213-26. |
| Rand D, Derdak Z, Carlson R, Wands JR, Rose-Petruck C. "Corrigendum: X-ray Scatter Imaging of Hepatocellular Carcinoma in a Mouse Model Using Nanoparticle Contrast Agents." Scientific reports, vol. 6, 2016, pp. 21229. |
| Huang CK, Aihara A, Iwagami Y, Yu T, Carlson R, Koga H, Kim M, Zou J, Casulli S, Wands JR. "Expression of transforming growth factor β1 promotes cholangiocarcinoma development and progression." Cancer Letters, vol. 380, no. 1, 2016, pp. 153-62. |
| Shapiro JM, Chung W, Ogawa K, Barker L, Carlson R, Wands JR, Li J. "Identification of Tumor Antigen AF20 as Glycosylated Transferrin Receptor 1 in Complex with Heat Shock Protein and/or Transporting ATPase." PLoS ONE, vol. 11, no. 11, 2016, pp. e0165227. |
| Aihara A, Wands JR, Tanaka S. "Molecular pathology of advanced hepatocellular carcinoma." Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, vol. 113, no. 5, 2016, pp. 790-7. |
| Erick TK, Anderson CK, Reilly EC, Wands JR, Brossay L. "NFIL3 Expression Distinguishes Tissue-Resident NK Cells and Conventional NK-like Cells in the Mouse Submandibular Glands." The Journal of Immunology, vol. 197, no. 6, 2016, pp. 2485-91. |
| Li J, Zong L, Sureau C, Barker L, Wands JR, Tong S. "Unusual Features of Sodium Taurocholate Cotransporting Polypeptide as a Hepatitis B Virus Receptor." Journal of Virology, vol. 90, no. 18, 2016, pp. 8302-13. |
| Li, Dan, Habr, Fadlallah, Wands, Jack R., Cao, Weibiao. "379 Expression of NOTCH Signaling Molecules in Barrett's Associated Adenocarcinoma." Gastroenterology, vol. 148, no. 4, 2015, pp. S-78-S-79. |
| Rand D, Walsh EG, Derdak Z, Wands JR, Rose-Petruck C. "A highly sensitive x-ray imaging modality for hepatocellular carcinoma detection in vitro." Physics in Medicine & Biology, vol. 60, no. 2, 2015, pp. 769-784. |
| Dong X, Lin Q, Aihara A, Li Y, Huang CK, Chung W, Tang Q, Chen X, Carlson R, Nadolny C, Gabriel G, Olsen M, Wands JR. "Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotype." Oncotarget, vol. 6, no. 2, 2015, pp. 1231-48. |
| Tomimaru, Yoshito, Mishra, Sasmita, Safran, Howard, Charpentier, Kevin P., Martin, William, De Groot, Anne S., Gregory, Stephen H., Wands, Jack R. "Aspartate-β-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinoma." Vaccine, vol. 33, no. 10, 2015, pp. 1256-66. |
| Li, Jisu, Wands, Jack. "Hepatitis B and D viral receptors." Hepatology, vol. 63, no. 1, 2015, pp. 11-13. |
| Huang CK, Yu T, de la Monte SM, Wands JR, Derdak Z, Kim M. "Restoration of Wnt/β-catenin signaling attenuates alcoholic liver disease progression in a rat model." Journal of Hepatology, vol. 63, no. 1, 2015, pp. 191-198. |
| Rand, Danielle, Derdak, Zoltan, Carlson, Rolf, Wands, Jack R., Rose-Petruck, Christoph. "X-ray Scatter Imaging of Hepatocellular Carcinoma in a Mouse Model Using Nanoparticle Contrast Agents." Sci. Rep., vol. 5, 2015, pp. 15673. |
| Aihara A, Huang CK, Olsen MJ, Lin Q, Chung W, Tang Q, Dong X, Wands JR. "A cell-surface β-hydroxylase is a biomarker and therapeutic target for hepatocellular carcinoma." Hepatology, vol. 60, no. 4, 2014, pp. 1302-13. |
| Koga, Hironori, Kim, Miran, Nakamura, Anna, Yano, Hirohisa, Abe, Mitsuhiko, Ikezono, Yu, Nakamura, Toru, Torimura, Takuji, Wands, Jack R., Sata, Michio. "Abstract 330: The Wnt signal transcription factor TCF-4 directly regulates Bcl-xL expression in human hepatocellular carcinoma cells." Cancer Research, vol. 74, no. 19 Supplement, 2014, pp. 330-330. |
| Lin Q, Aihara A, Chung W, Li Y, Huang Z, Chen X, Weng S, Carlson RI, Wands JR, Dong X. "LRH1 as a driving factor in pancreatic cancer growth." Cancer Letters, vol. 345, no. 1, 2014, pp. 85-90. |
| Lin Q, Aihara A, Chung W, Li Y, Chen X, Huang Z, Weng S, Carlson RI, Nadolny C, Wands JR, Dong X. "LRH1 promotes pancreatic cancer metastasis." Cancer Letters, vol. 350, no. 1-2, 2014, pp. 15-24. |
| Lang CH, Derdak Z, Wands JR. "Strain-dependent differences for suppression of insulin-stimulated glucose uptake in skeletal and cardiac muscle by ethanol." Alcoholism: Clinical and Experimental Research, vol. 38, no. 4, 2014, pp. 897-910. |
| Tong M, Longato L, Ramirez T, Zabala V, Wands JR, de la Monte SM. "Therapeutic reversal of chronic alcohol-related steatohepatitis with the ceramide inhibitor myriocin." International journal of experimental pathology, vol. 95, no. 1, 2014, pp. 49-63. |
| Wands JR, Kim M. "WNT/β-catenin signaling and hepatocellular carcinoma." Hepatology, vol. 60, no. 2, 2014, pp. 452-4. |
| Derdak, Z., Sousa, A., Wu, A., Wands, J. "549 INHIBITION OF p53 MITIGATES ETHANOL-INDUCED TIGAR UPREGULATION, REDUCTIVE STRESS AND SUBSEQUENTLY IMPROVES HEPATIC INSULIN SIGNALING IN THE LIVERS OF ETHANOL-FED LONG–EVANS RATS." Journal of Hepatology, vol. 58, 2013, pp. S224-S225. |
| Derdak, Z., Wu, A., Sousa, A., Wands, J. "550 TIGAR PROMOTES INSULIN RESISTANCE BY INCREASING REDUCTIVE STRESS IN ETHANOL-TREATED HUMAN HepaRG CELLS." Journal of Hepatology, vol. 58, 2013, pp. S225. |
| Koga, Hironori, Kim, Miran, Tomimaru, Yoshito, Nakamura, Toru, Abe, Mitsuhiko, Hashimoto, Osamu, Ikezono, Yu, Masuda, Hiroshi, Yano, Hirohisa, Ueno, Takato, Torimura, Takuji, Wands, Jack R., Sata, Michio. "Abstract 890: Human TCF-4 isoforms regulate apoptosis through upregulating Bcl-xL expression in a SxxSS motif-dependent manner." Cancer Research, vol. 73, no. 8 Supplement, 2013, pp. 890-890. |
| Ramirez T, Tong M, Chen WC, Nguyen QG, Wands JR, de la Monte SM. "Chronic alcohol-induced hepatic insulin resistance and endoplasmic reticulum stress ameliorated by peroxisome-proliferator activated receptor-δ agonist treatment." Journal of gastroenterology and hepatology, vol. 28, no. 1, 2013, pp. 179-87. |
| Ortiz, Vivian, Wands, Jack R. "Chronic ethanol diet increases regulatory T-cell activity and inhibits hepatitis C virus core-specific cellular immune responses in mice." Hepatology research : the official journal of the Japan Society of Hepatology, vol. 44, no. 7, 2013, pp. 788-797. |
| Tong S, Li J, Wands JR, Wen YM. "Hepatitis B virus genetic variants: biological properties and clinical implications." Emerging microbes & infections, vol. 2, no. 3, 2013, pp. e10. |
| Kwei K, Tang X, Lok AS, Sureau C, Garcia T, Li J, Wands J, Tong S. "Impaired virion secretion by hepatitis B virus immune escape mutants and its rescue by wild-type envelope proteins or a second-site mutation." Journal of Virology, vol. 87, no. 4, 2013, pp. 2352-7. |
| Derdak Z, Villegas KA, Harb R, Wu AM, Sousa A, Wands JR. "Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease." Journal of Hepatology, vol. 58, no. 4, 2013, pp. 785-91. |
| Ramirez T, Longato L, Dostalek M, Tong M, Wands JR, de la Monte SM. "Insulin resistance, ceramide accumulation and endoplasmic reticulum stress in experimental chronic alcohol-induced steatohepatitis." Alcohol and Alcoholism, vol. 48, no. 1, 2013, pp. 39-52. |
| Tomimaru Y, Xu CQ, Nambotin SB, Yan T, Wands JR, Kim M. "Loss of exon 4 in a human T-cell factor-4 isoform promotes hepatic tumourigenicity." Liver international : official journal of the International Association for the Study of the Liver, vol. 33, no. 10, 2013, pp. 1536-48. |
| Li, Dan, Wands, Jack R., Cao, Weibiao. "Mo1855 Role of HOXD9 in Acid-Induced Increase in Cell Proliferation in Barrett's Esophageal Adenocarcinoma Cells." Gastroenterology, vol. 144, no. 5, 2013, pp. S-676. |
| Li, Dan, Wands, Jack R., Souza, Rhonda F., Cao, Weibiao. "Mo1958 Acid-Induced Production of Interleukin-1β Causes DNA Damage in Barrett's Cells." Gastroenterology, vol. 144, no. 5, 2013, pp. S-704. |
| Zhou X, Li D, Resnick MB, Wands J, Cao W. "NADPH oxidase NOX5-S and nuclear factor κB1 mediate acid-induced microsomal prostaglandin E synthase-1 expression in Barrett's esophageal adenocarcinoma cells." Molecular pharmacology, vol. 83, no. 5, 2013, pp. 978-90. |
| Hong J, Li D, Wands J, Souza R, Cao W. "Role of NADPH oxidase NOX5-S, NF-κB, and DNMT1 in acid-induced p16 hypermethylation in Barrett's cells." AJP: Cell Physiology, vol. 305, no. 10, 2013, pp. C1069-79. |
| Li, Dan, Wands, Jack R., Cao, Weibiao. "Sa2015 Signaling in Bile Acid-Induced DNA Damage in Barrett's Esophageal Adenocarcinoma Cells." Gastroenterology, vol. 144, no. 5, 2013, pp. S-360. |
| Engels M, Wang C, Matoso A, Maidan E, Wands J. "Tea not Tincture: Hepatotoxicity Associated with Rooibos Herbal Tea." ACG Case Reports Journal, vol. 1, no. 1, 2013, pp. 58-60. |
| Tomimaru Y, Koga H, Shin TH, Xu CQ, Wands JR, Kim M. "The SxxSS motif of T-cell factor-4 isoforms modulates Wnt/β-catenin signal activation in hepatocellular carcinoma cells." Cancer Letters, vol. 336, no. 2, 2013, pp. 359-69. |
| Tomimaru Y, Koga H, Yano H, de la Monte S, Wands JR, Kim M. "Upregulation of T-cell factor-4 isoform-responsive target genes in hepatocellular carcinoma." Liver international : official journal of the International Association for the Study of the Liver, vol. 33, no. 7, 2013, pp. 1100-12. |
| Pez F, Lopez A, Kim M, Wands JR, Caron de Fromentel C, Merle P. "Wnt signaling and hepatocarcinogenesis: molecular targets for the development of innovative anticancer drugs." Journal of Hepatology, vol. 59, no. 5, 2013, pp. 1107-17. |
| Derdak, Z., Sack, J., Harb, R., Wands, J.R. "1346 INHIBITION OF P53 ATTENUATES INSULIN RESISTANCE AND LIVER INJURY IN ETHANOL-FED LONG-EVANS RATS." Journal of Hepatology, vol. 56, 2012, pp. S529. |
| Reilly EC, Thompson EA, Aspeslagh S, Wands JR, Elewaut D, Brossay L. "Activated iNKT cells promote memory CD8+ T cell differentiation during viral infection." PLoS ONE, vol. 7, no. 5, 2012, pp. e37991. |
| de la Monte S, Derdak Z, Wands JR. "Alcohol, insulin resistance and the liver-brain axis." Journal of gastroenterology and hepatology, vol. 27 Suppl 2, 2012, pp. 33-41. |
| Derdak Z, Villegas KA, Wands JR. "Early growth response-1 transcription factor promotes hepatic fibrosis and steatosis in long-term ethanol-fed Long-Evans rats." Liver international : official journal of the International Association for the Study of the Liver, vol. 32, no. 5, 2012, pp. 761-70. |
| Nambotin SB, Tomimaru Y, Merle P, Wands JR, Kim M. "Functional consequences of WNT3/Frizzled7-mediated signaling in non-transformed hepatic cells." Oncogenesis, vol. 1, 2012, pp. e31. |
| Longato L, Tong M, Wands JR, de la Monte SM. "High fat diet induced hepatic steatosis and insulin resistance: Role of dysregulated ceramide metabolism." Hepatology research : the official journal of the Japan Society of Hepatology, vol. 42, no. 4, 2012, pp. 412-27. |
| Noda T, Shimoda M, Ortiz V, Sirica AE, Wands JR. "Immunization with aspartate-β-hydroxylase-loaded dendritic cells produces antitumor effects in a rat model of intrahepatic cholangiocarcinoma." Hepatology, vol. 55, no. 1, 2012, pp. 86-97. |
| Longato L, Ripp K, Setshedi M, Dostalek M, Akhlaghi F, Branda M, Wands JR, de la Monte SM. "Insulin resistance, ceramide accumulation, and endoplasmic reticulum stress in human chronic alcohol-related liver disease." Oxidative medicine and cellular longevity, vol. 2012, 2012, pp. 479348. |
| Koga H, Tsedensodnom O, Tomimaru Y, Walker EJ, Lee HC, Kim KM, Yano H, Wands JR, Kim M. "Loss of the SxxSS motif in a human T-cell factor-4 isoform confers hypoxia resistance to liver cancer: an oncogenic switch in Wnt signaling." PLoS ONE, vol. 7, no. 6, 2012, pp. e39981. |
| Ramirez T, Tong M, Ayala CA, Monfils PR, McMillan PN, Zabala V, Wands JR, de la Monte SM. "Structural Correlates of PPAR Agonist Rescue of Experimental Chronic Alcohol-Induced Steatohepatitis." Journal of clinical & experimental pathology, vol. 2, no. 4, 2012. |
| Shimoda M, Tomimaru Y, Charpentier KP, Safran H, Carlson RI, Wands J. "Tumor progression-related transmembrane protein aspartate-β-hydroxylase is a target for immunotherapy of hepatocellular carcinoma." Journal of Hepatology, vol. 56, no. 5, 2012, pp. 1129-35. |
| Koga, Hironori, Walker, Evan J., Tsedensodnom, Orkhontuya, Wands, Jack R., Kim, Miran. "Abstract 1933: Preferential ubiquitination of hypoxia-inducible factors depends on the SxxSS motif in human T-cell factor-4 isoforms derived from hepatocellular carcinoma." Cancer Research, vol. 71, no. 8 Supplement, 2011, pp. 1933-1933. |
| Derdak Z, Lang CH, Villegas KA, Tong M, Mark NM, de la Monte SM, Wands JR. "Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease." Journal of Hepatology, vol. 54, no. 1, 2011, pp. 164-72. |
| Gutelius D, Li J, Wands J, Tong S. "Characterization of the pleiotropic effects of the genotype G-specific 36-nucleotide insertion in the context of other hepatitis B virus genotypes." Journal of Virology, vol. 85, no. 24, 2011, pp. 13278-89. |
| Feng D, Eken A, Ortiz V, Wands JR. "Chronic alcohol-induced liver disease inhibits dendritic cell function." Liver international : official journal of the International Association for the Study of the Liver, vol. 31, no. 7, 2011, pp. 950-63. |
| Eken A, Ortiz V, Wands JR. "Ethanol inhibits antigen presentation by dendritic cells." Clinical and vaccine immunology : CVI, vol. 18, no. 7, 2011, pp. 1157-66. |
| Qin Y, Tang X, Garcia T, Hussain M, Zhang J, Lok A, Wands J, Li J, Tong S. "Hepatitis B virus genotype C isolates with wild-type core promoter sequence replicate less efficiently than genotype B isolates but possess higher virion secretion capacity." Journal of Virology, vol. 85, no. 19, 2011, pp. 10167-77. |
| Tsedensodnom O, Koga H, Rosenberg SA, Nambotin SB, Carroll JJ, Wands JR, Kim M. "Identification of T-cell factor-4 isoforms that contribute to the malignant phenotype of hepatocellular carcinoma cells." Experimental Cell Research, vol. 317, no. 7, 2011, pp. 920-31. |
| Qin Y, Zhang J, Garcia T, Ito K, Gutelius D, Li J, Wands J, Tong S. "Improved method for rapid and efficient determination of genome replication and protein expression of clinical hepatitis B virus isolates." Journal of clinical microbiology, vol. 49, no. 4, 2011, pp. 1226-33. |
| Setshedi M, Longato L, Petersen DR, Ronis M, Chen WC, Wands JR, de la Monte SM. "Limited therapeutic effect of N-acetylcysteine on hepatic insulin resistance in an experimental model of alcohol-induced steatohepatitis." Alcoholism: Clinical and Experimental Research, vol. 35, no. 12, 2011, pp. 2139-51. |
| Rand, Danielle, Ortiz, Vivian, Liu, Yanan, Derdak, Zoltan, Wands, Jack R., Tatíček, Milan, Rose-Petruck, Christoph. "Nanomaterials for X-ray Imaging: Gold Nanoparticle Enhancement of X-ray Scatter Imaging of Hepatocellular Carcinoma." Nano Letters, vol. 11, no. 7, 2011, pp. 2678-2683. |
| de la Monte SM, Pang M, Chaudhry R, Duan K, Longato L, Carter J, Ouh J, Wands JR. "Peroxisome proliferator-activated receptor agonist treatment of alcohol-induced hepatic insulin resistance." Hepatology research : the official journal of the Japan Society of Hepatology, vol. 41, no. 4, 2011, pp. 386-98. |
| Nambotin SB, Lefrancois L, Sainsily X, Berthillon P, Kim M, Wands JR, Chevallier M, Jalinot P, Scoazec JY, Trepo C, Zoulim F, Merle P. "Pharmacological inhibition of Frizzled-7 displays anti-tumor properties in hepatocellular carcinoma." Journal of Hepatology, vol. 54, no. 2, 2011, pp. 288-99. |
| Nambotin SB, Wands JR, Kim M. "Points of therapeutic intervention along the Wnt signaling pathway in hepatocellular carcinoma." Anti-cancer agents in medicinal chemistry, vol. 11, no. 6, 2011, pp. 549-59. |
| Hong J, Resnick M, Behar J, Wands J, DeLellis RA, Cao W. "Role of Rac1 in regulation of NOX5-S function in Barrett's esophageal adenocarcinoma cells." AJP: Cell Physiology, vol. 301, no. 2, 2011, pp. C413-20. |
| Walker EJ, Rosenberg SA, Wands JR, Kim M. "Role of Raf Kinase Inhibitor Protein in Hepatocellular Carcinoma." Forum on immunopathological diseases and therapeutics, vol. 2, no. 2, 2011, pp. 195-204. |
| Zhou X, Li D, Resnick MB, Behar J, Wands J, Cao W. "Signaling in H2O2-induced increase in cell proliferation in Barrett's esophageal adenocarcinoma cells." The Journal of pharmacology and experimental therapeutics, vol. 339, no. 1, 2011, pp. 218-27. |
| Yan T, Li K, Li F, Su H, Mu J, Tong S, Patel M, Xia J, Wands JR, Wang H. "T1846 and A/G1913 are associated with acute on chronic liver failure in patients infected with hepatitis B virus genotypes B and C." Journal of medical virology, vol. 83, no. 6, 2011, pp. 996-1004. |
| Promrat K, Longato L, Wands JR, de la Monte SM. "Weight loss amelioration of non-alcoholic steatohepatitis linked to shifts in hepatic ceramide expression and serum ceramide levels." Hepatology research : the official journal of the Japan Society of Hepatology, vol. 41, no. 8, 2011, pp. 754-62. |
| Setshedi M, Wands JR, Monte SM. "Acetaldehyde adducts in alcoholic liver disease." Oxidative medicine and cellular longevity, vol. 3, no. 3, 2010, pp. 178-85. |
| Hong J, Resnick M, Behar J, Wang LJ, Wands J, DeLellis RA, Souza RF, Spechler SJ, Cao W. "Acid-induced p16 hypermethylation contributes to development of esophageal adenocarcinoma via activation of NADPH oxidase NOX5-S." American journal of physiology. Gastrointestinal and liver physiology, vol. 299, no. 3, 2010, pp. G697-706. |
| Szabo G, Wands JR, Eken A, Osna NA, Weinman SA, Machida K, Joe Wang H. "Alcohol and hepatitis C virus--interactions in immune dysfunctions and liver damage." Alcoholism: Clinical and Experimental Research, vol. 34, no. 10, 2010, pp. 1675-86. |
| Lawton M, Tong M, Gundogan F, Wands JR, de la Monte SM. "Aspartyl-(asparaginyl) beta-hydroxylase, hypoxia-inducible factor-alpha and Notch cross-talk in regulating neuronal motility." Oxidative medicine and cellular longevity, vol. 3, no. 5, 2010, pp. 347-56. |
| Hong J, Behar J, Wands J, Resnick M, Wang LJ, Delellis RA, Lambeth D, Cao W. "Bile acid reflux contributes to development of esophageal adenocarcinoma via activation of phosphatidylinositol-specific phospholipase Cgamma2 and NADPH oxidase NOX5-S." Cancer Research, vol. 70, no. 3, 2010, pp. 1247-55. |
| de la Monte SM, Tong M, Nguyen V, Setshedi M, Longato L, Wands JR. "Ceramide-mediated insulin resistance and impairment of cognitive-motor functions." Journal of Alzheimer's disease : JAD, vol. 21, no. 3, 2010, pp. 967-84. |
| Reilly EC, Wands JR, Brossay L. "Cytokine dependent and independent iNKT cell activation." Cytokine, vol. 51, no. 3, 2010, pp. 227-31. |
| Wintermeyer P, Gehring S, Eken A, Wands JR. "Generation of cellular immune responses to HCV NS5 protein through in vivo activation of dendritic cells." Journal of viral hepatitis, vol. 17, no. 10, 2010, pp. 705-13. |
| von dem Bussche A, Machida R, Li K, Loevinsohn G, Khander A, Wang J, Wakita T, Wands JR, Li J. "Hepatitis C virus NS2 protein triggers endoplasmic reticulum stress and suppresses its own viral replication." Journal of Hepatology, vol. 53, no. 5, 2010, pp. 797-804. |
| Wintermeyer, P, Gehring, S, Eken, A, Wirth, S, Wands, JR. "Immunisierung gegen HCV durch direktes Beimpfen von Dendritischen Zellen mit NS5-Protein in vivo im Mausmodell." Klinische Pädiatrie, vol. 222, no. S 01, 2010. |
| Ito K, Qin Y, Guarnieri M, Garcia T, Kwei K, Mizokami M, Zhang J, Li J, Wands JR, Tong S. "Impairment of hepatitis B virus virion secretion by single-amino-acid substitutions in the small envelope protein and rescue by a novel glycosylation site." Journal of Virology, vol. 84, no. 24, 2010, pp. 12850-61. |
| Tong Y, Tong S, Zhao X, Wang J, Jun J, Park J, Wands J, Li J. "Initiation of duck hepatitis B virus infection requires cleavage by a furin-like protease." Journal of Virology, vol. 84, no. 9, 2010, pp. 4569-78. |
| Toyama T, Lee HC, Koga H, Wands JR, Kim M. "Noncanonical Wnt11 inhibits hepatocellular carcinoma cell proliferation and migration." Molecular Cancer Research, vol. 8, no. 2, 2010, pp. 254-65. |
| Promrat K, Kleiner DE, Niemeier HM, Jackvony E, Kearns M, Wands JR, Fava JL, Wing RR. "Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis." Hepatology, vol. 51, no. 1, 2010, pp. 121-9. |
| Denucci SM, Tong M, Longato L, Lawton M, Setshedi M, Carlson RI, Wands JR, de la Monte SM. "Rat strain differences in susceptibility to alcohol-induced chronic liver injury and hepatic insulin resistance." Gastroenterology research and practice, vol. 2010, 2010. |
| Hong J, Behar J, Wands J, Resnick M, Wang LJ, DeLellis RA, Lambeth D, Souza RF, Spechler SJ, Cao W. "Role of a novel bile acid receptor TGR5 in the development of oesophageal adenocarcinoma." Gut, vol. 59, no. 2, 2010, pp. 170-80. |
| de la Monte SM, Wands JR. "Role of central nervous system insulin resistance in fetal alcohol spectrum disorders." Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharamcologie clinique, vol. 17, no. 3, 2010, pp. e390-404. |
| Hong, Jie, Resnick, Murray, Behar, Jose, Wang, Li Juan, Wands, Jack R., DeLellis, Ronald A., Lambeth, David, Souza, Rhonda F., Spechler, Stuart J., Cao, Weibiao. "S1062 Acid-Induced p16 Hypermethylation Contributes to Development of Esophageal Adenocarcinoma via Activation of NADPH Oxidase NOX5-S." Gastroenterology, vol. 138, no. 5, 2010, pp. S-170. |
| Hong, Jie, Resnick, Murray, Behar, Jose, Wands, Jack R., Wang, Li Juan, DeLellis, Ronald A., Lambeth, David, Cao, Weibiao. "S1063 The Bile Acid Receptor TGR5 and NADPH Oxidase NOX5-S Mediate Bile Acid-Induced Increase in Cell Proliferation in Barrett's Esophageal Adenocarcinoma Cells." Gastroenterology, vol. 138, no. 5, 2010, pp. S-170. |
| Setshedi, Mashiko, Longato, Lisa, Ronis, Martin, Wands, Jack R., de la Monte, Suzanne M. "S1846 N-Acetylcysteine Improves Hepatic Insulin Resistance Associated With High-Fat Diet and Alcohol-Induced Steatohepatitis." Gastroenterology, vol. 138, no. 5, 2010, pp. S-801. |
| He J, de la Monte S, Wands JR. "The p85beta regulatory subunit of PI3K serves as a substrate for PTEN protein phosphatase activity during insulin mediated signaling." Biochemical and Biophysical Research Communications, vol. 397, no. 3, 2010, pp. 513-9. |
| Hong, Jie, Behar, Jose, Resnick, Murray, Wang, Li Juan, DeLellis, Ronald A., Wands, Jack R., Cao, Weibiao. "578 MEK1 Kinase and Rho Kinase ROCK2 Mediate Acid-Induced NOX5-S Expression and H2O2 Production in Barrett's Esophageal Adenocarcinoma Cells." Gastroenterology, vol. 136, no. 5, 2009, pp. A-92. |
| Tsai A, Kawai S, Kwei K, Gewaily D, Hutter A, Tong DR, Li J, Wands JR, Tong S. "Chimeric constructs between two hepatitis B virus genomes confirm transcriptional impact of core promoter mutations and reveal multiple effects of core gene mutations." Virology, vol. 387, no. 2, 2009, pp. 364-72. |
| Garcia T, Li J, Sureau C, Ito K, Qin Y, Wands J, Tong S. "Drastic reduction in the production of subviral particles does not impair hepatitis B virus virion secretion." Journal of Virology, vol. 83, no. 21, 2009, pp. 11152-65. |
| de la Monte SM, Tong M, Carlson RI, Carter JJ, Longato L, Silbermann E, Wands JR. "Ethanol inhibition of aspartyl-asparaginyl-beta-hydroxylase in fetal alcohol spectrum disorder: potential link to the impairments in central nervous system neuronal migration." Alcohol, vol. 43, no. 3, 2009, pp. 225-40. |
| Gehring S, Gregory SH, Wintermeyer P, Aloman C, Wands JR. "Generation of immune responses against hepatitis C virus by dendritic cells containing NS5 protein-coated microparticles." Clinical and vaccine immunology : CVI, vol. 16, no. 2, 2009, pp. 163-71. |
| Lyn-Cook LE Jr, Lawton M, Tong M, Silbermann E, Longato L, Jiao P, Mark P, Wands JR, Xu H, de la Monte SM. "Hepatic ceramide may mediate brain insulin resistance and neurodegeneration in type 2 diabetes and non-alcoholic steatohepatitis." Journal of Alzheimer's disease : JAD, vol. 16, no. 4, 2009, pp. 715-29. |
| Siu L, Foont J, Wands JR. "Hepatitis C virus and alcohol." Seminars in liver disease, vol. 29, no. 2, 2009, pp. 188-99. |
| de la Monte SM, Longato L, Tong M, Wands JR. "Insulin resistance and neurodegeneration: roles of obesity, type 2 diabetes mellitus and non-alcoholic steatohepatitis." Current opinion in investigational drugs (London, England : 2000), vol. 10, no. 10, 2009, pp. 1049-60. |
| Tong M, Neusner A, Longato L, Lawton M, Wands JR, de la Monte SM. "Nitrosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer's disease." Journal of Alzheimer's disease : JAD, vol. 17, no. 4, 2009, pp. 827-44. |
| Longato L, de la Monte S, Kuzushita N, Horimoto M, Rogers AB, Slagle BL, Wands JR. "Overexpression of insulin receptor substrate-1 and hepatitis Bx genes causes premalignant alterations in the liver." Hepatology, vol. 49, no. 6, 2009, pp. 1935-43. |
| Sungarian A, Cielo D, Sampath P, Bowling N, Moskal P, Wands JR, de la Monte SM. "Potential Role of Thymosin-alpha1 Adjuvant Therapy for Glioblastoma." Journal of oncology, vol. 2009, 2009, pp. 302084. |
| Pang M, de la Monte SM, Longato L, Tong M, He J, Chaudhry R, Duan K, Ouh J, Wands JR. "PPARdelta agonist attenuates alcohol-induced hepatic insulin resistance and improves liver injury and repair." Journal of Hepatology, vol. 50, no. 6, 2009, pp. 1192-201. |
| Qin Y, Zhang J, Mao R, Guo H, Yin Y, Wu X, Weng X, Wands J, Tong S. "Prevalence of basal core promoter and precore mutations in Chinese chronic hepatitis B patients and correlation with serum HBeAG titers." Journal of medical virology, vol. 81, no. 5, 2009, pp. 807-14. |
| Luu M, Sabo E, de la Monte SM, Greaves W, Wang J, Tavares R, Simao L, Wands JR, Resnick MB, Wang L. "Prognostic value of aspartyl (asparaginyl)-beta-hydroxylase/humbug expression in non-small cell lung carcinoma." Human Pathology, vol. 40, no. 5, 2009, pp. 639-44. |
| de la Monte SM, Longato L, Tong M, DeNucci S, Wands JR. "The liver-brain axis of alcohol-mediated neurodegeneration: role of toxic lipids." International Journal of Environmental Research and Public Health, vol. 6, no. 7, 2009, pp. 2055-75. |
| Pritchard JR, Cosgrove BD, Hemann MT, Griffith LG, Wands JR, Lauffenburger DA. "Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death." Molecular Cancer Therapeutics, vol. 8, no. 8, 2009, pp. 2183-92. |
| Addolorato G, Russell M, Albano E, Haber PS, Wands JR, Leggio L. "Understanding and treating patients with alcoholic cirrhosis: an update." Alcoholism: Clinical and Experimental Research, vol. 33, no. 7, 2009, pp. 1136-44. |
| Hamilton, Theron J., Bailat, Claude, Gehring, Stephan, Laperle, Christopher M., Wands, Jack, Rose-Petruck, Christoph, Diebold, Gerald J. "X-ray elastography: Modification of x-ray phase contrast images using ultrasonic radiation pressure." J. Appl. Phys., vol. 105, no. 10, 2009, pp. 102001. |
| de la Monte, S. M., Wands, J. R. "Alzheimer's Disease is Type 3 Diabetes--Evidence Reviewed." Journal of Diabetes Science and Technology, vol. 2, no. 6, 2008, pp. 1101-1113. |
| de la Monte SM, Wands JR. "Alzheimer's disease is type 3 diabetes-evidence reviewed." Journal of Diabetes Science and Technology, vol. 2, no. 6, 2008, pp. 1101-13. |
| Bengochea A, de Souza MM, Lefrançois L, Le Roux E, Galy O, Chemin I, Kim M, Wands JR, Trepo C, Hainaut P, Scoazec JY, Vitvitski L, Merle P. "Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma." Br J Cancer, vol. 99, no. 1, 2008, pp. 143-50. |
| Carter JJ, Tong M, Silbermann E, Lahousse SA, Ding FF, Longato L, Roper N, Wands JR, de la Monte SM. "Ethanol impaired neuronal migration is associated with reduced aspartyl-asparaginyl-beta-hydroxylase expression." Acta Neuropathologica, vol. 116, no. 3, 2008, pp. 303-15. |
| Kim E, Li K, Lieu C, Tong S, Kawai S, Fukutomi T, Zhou Y, Wands J, Li J. "Expression of apolipoprotein C-IV is regulated by Ku antigen/peroxisome proliferator-activated receptor gamma complex and correlates with liver steatosis." Journal of Hepatology, vol. 49, no. 5, 2008, pp. 787-98. |
| Kim M, Lee HC, Tsedensodnom O, Hartley R, Lim YS, Yu E, Merle P, Wands JR. "Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells." Journal of Hepatology, vol. 48, no. 5, 2008, pp. 780-91. |
| Gehring S, Gregory SH, Wintermeyer P, San Martin M, Aloman C, Wands JR. "Generation and characterization of an immunogenic dendritic cell population." Journal of immunological methods, vol. 332, no. 1-2, 2008, pp. 18-30. |
| Wands, J.R. "I-65 Hepatitis B and C viral-cellular interactions in the pathogenesis of hepatocellular carcinoma." International Journal of Infectious Diseases, vol. 12, 2008, pp. S23. |
| Gundogan F, Elwood G, Longato L, Tong M, Feijoo A, Carlson RI, Wands JR, de la Monte SM. "Impaired placentation in fetal alcohol syndrome." Placenta, vol. 29, no. 2, 2008, pp. 148-57. |
| de la Monte SM, Tong M, Cohen AC, Sheedy D, Harper C, Wands JR. "Insulin and insulin-like growth factor resistance in alcoholic neurodegeneration." Alcoholism: Clinical and Experimental Research, vol. 32, no. 9, 2008, pp. 1630-44. |
| de la Monte SM, Yeon JE, Tong M, Longato L, Chaudhry R, Pang MY, Duan K, Wands JR. "Insulin resistance in experimental alcohol-induced liver disease." Journal of gastroenterology and hepatology, vol. 23, no. 8 Pt 2, 2008, pp. e477-86. |
| Laperle CM, Hamilton TJ, Wintermeyer P, Walker EJ, Shi D, Anastasio MA, Derdak Z, Wands JR, Diebold G, Rose-Petruck C. "Low density contrast agents for x-ray phase contrast imaging: the use of ambient air for x-ray angiography of excised murine liver tissue." Physics in Medicine & Biology, vol. 53, no. 23, 2008, pp. 6911-23. |
| Hong, Jie, Behar, Jose, Wands, Jack R., Lambeth, John David, Cao, Weibiao. "M1965 Phosphatidylinositol-Specific Phospholipase C (PI-PLC) Mediates Bile Acid-Induced NADPH Oxidase NOX5-S Expression in Barrett's Esophageal Adenocarcinoma Cells." Gastroenterology, vol. 134, no. 4, 2008, pp. A-441. |
| Si, Jin, Hong, Jie, Behar, Jose, Wands, Jack R., Souza, Rhonda F., Spechler, Stuart J., Lambeth, John David, Cao, Weibiao. "M1966 NADPH Oxidase NOX5-S Mediates Cyclin D1 Expression in Barrett's Esophageal Adenocarcinoma Cells." Gastroenterology, vol. 134, no. 4, 2008, pp. A-441. |
| Trevisani F, Cantarini MC, Wands JR, Bernardi M. "Recent advances in the natural history of hepatocellular carcinoma." Carcinogenesis, vol. 29, no. 7, 2008, pp. 1299-305. |
| DeNucci, Sarah M., de la Monte, Suzanne M., Tong, Ming, Wands, Jack R. "S1928 Molecular and Histopathological Analyses of Experimental Rat Models of Low, Intermediate, or High Susceptibility to Alcohol-Induced Liver Injury." Gastroenterology, vol. 134, no. 4, 2008, pp. A-786. |
| Si J, Behar J, Wands J, Beer DG, Lambeth D, Chin YE, Cao W. "STAT5 mediates PAF-induced NADPH oxidase NOX5-S expression in Barrett's esophageal adenocarcinoma cells." American journal of physiology. Gastrointestinal and liver physiology, vol. 294, no. 1, 2008, pp. G174-83. |
| Longato L, de la Monte S, Califano S, Wands JR. "Synergistic premalignant effects of chronic ethanol exposure and insulin receptor substrate-1 overexpression in liver." Hepatology research : the official journal of the Japan Society of Hepatology, vol. 38, no. 9, 2008, pp. 940-53. |
| Pang, Maoyin, de la Monte, Suzanne M., Chaudhry, Rajeeve, Duan, Kevin, Ouh, Jiyun, Carter, Jade, Wands, Jack R. "T1780 Peroxisome Proliferator-Activated Receptor Agonist Effects On Alcohol-Induced Hepatic Insulin Resistance." Gastroenterology, vol. 134, no. 4, 2008, pp. A-820. |
| Derdak Z, Mark NM, Beldi G, Robson SC, Wands JR, Baffy G. "The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cells." Cancer Research, vol. 68, no. 8, 2008, pp. 2813-9. |
| Mohr L, Banerjee K, Kleinschmidt M, Bartolomé Rodríguez MM, Wands JR. "Transgenic overexpression of insulin receptor substrate 1 in hepatocytes enhances hepatocellular proliferation in young mice only." Hepatology research : the official journal of the Japan Society of Hepatology, vol. 38, no. 12, 2008, pp. 1233-40. |
| Sheets AR, Fülöp P, Derdák Z, Kassai A, Sabo E, Mark NM, Paragh G, Wands JR, Baffy G. "Uncoupling protein-2 modulates the lipid metabolic response to fasting in mice." American journal of physiology. Gastrointestinal and liver physiology, vol. 294, no. 4, 2008, pp. G1017-24. |
| Derdak, Zoltan, Mark, Nicholas M., Garcia, Tamako A., Beldi, Guido, Robson, Simon C., Wands, Jack R., Baffy, Gyorgy. "W1965 Uncoupling Protein-2 Alters the p53 Response and the Bioenergetics of Colon Cancer Cells." Gastroenterology, vol. 134, no. 4, 2008, pp. A-744. |
| Spaisman, Amy, Tong, Ming, Ding, Fei-Fei, Wands, Jack, de la Monte, Suzanne. "Acetaldehyde-mediated neurotoxicity." Journal of Neuropathology and Experimental Neurology, vol. 66, no. 5, 2007, pp. 451. |
| He J, de la Monte S, Wands JR. "Acute ethanol exposure inhibits insulin signaling in the liver." Hepatology, vol. 46, no. 6, 2007, pp. 1791-800. |
| Ronis MJ, Wands JR, Badger TM, de la Monte SM, Lang CH, Calissendorff J. "Alcohol-induced disruption of endocrine signaling." Alcoholism: Clinical and Experimental Research, vol. 31, no. 8, 2007, pp. 1269-85. |
| de la Monte, Suzanne, Tong, Ming, Ding, Fei Fei, Luks, Valerie, Wands, Jack. "Brain insulin or insulin-like growth factor depletion causes fetal alcohol syndrome-like neurodevelopmental abnormalities." Journal of Neuropathology and Experimental Neurology, vol. 66, no. 5, 2007, pp. 436-437. |
| Aloman C, Gehring S, Wintermeyer P, Kuzushita N, Wands JR. "Chronic ethanol consumption impairs cellular immune responses against HCV NS5 protein due to dendritic cell dysfunction." Gastroenterology, vol. 132, no. 2, 2007, pp. 698-708. |
| Li K, Zoulim F, Pichoud C, Kwei K, Villet S, Wands J, Li J, Tong S. "Critical role of the 36-nucleotide insertion in hepatitis B virus genotype G in core protein expression, genome replication, and virion secretion." Journal of Virology, vol. 81, no. 17, 2007, pp. 9202-15. |
| Wands J. "Hepatocellular carcinoma and sex." New England Journal of Medicine, vol. 357, no. 19, 2007, pp. 1974-6. |
| Cohen AC, Tong M, Wands JR, de la Monte SM. "Insulin and insulin-like growth factor resistance with neurodegeneration in an adult chronic ethanol exposure model." Alcoholism: Clinical and Experimental Research, vol. 31, no. 9, 2007, pp. 1558-73. |
| Yeung YA, Finney AH, Koyrakh IA, Lebowitz MS, Ghanbari HA, Wands JR, Wittrup KD. "Isolation and characterization of human antibodies targeting human aspartyl (asparaginyl) beta-hydroxylase." Human antibodies, vol. 16, no. 3-4, 2007, pp. 163-76. |
| Si J, Fu X, Behar J, Wands J, Beer DG, Souza RF, Spechler SJ, Lambeth D, Cao W. "NADPH oxidase NOX5-S mediates acid-induced cyclooxygenase-2 expression via activation of NF-kappaB in Barrett's esophageal adenocarcinoma cells." Journal of Biological Chemistry, vol. 282, no. 22, 2007, pp. 16244-55. |
| de la Monte SM, Jhaveri A, Maron BA, Wands JR. "Nitric oxide synthase 3-mediated neurodegeneration after intracerebral gene delivery." Journal of Neuropathology and Experimental Neurology, vol. 66, no. 4, 2007, pp. 272-83. |
| Wang J, de la Monte SM, Sabo E, Kethu S, Tavares R, Branda M, Simao L, Wands JR, Resnick MB. "Prognostic value of humbug gene overexpression in stage II colon cancer." Human Pathology, vol. 38, no. 1, 2007, pp. 17-25. |
| Laperle, Christopher M., Wintermeyer, Philip, Wands, Jack R., Shi, Daxin, Anastasio, Mark A., Li, Xiaodi, Ahr, Brian, Diebold, Gerald J., Rose-Petruck, Christoph. "Propagation based differential phase contrast imaging and tomography of murine tissue with a laser plasma x-ray source." Appl. Phys. Lett., vol. 91, no. 17, 2007, pp. 173901. |
| Gundogan F, Elwood G, Greco D, Rubin LP, Pinar H, Carlson RI, Wands JR, de la Monte SM. "Role of aspartyl-(asparaginyl) beta-hydroxylase in placental implantation: Relevance to early pregnancy loss." Human Pathology, vol. 38, no. 1, 2007, pp. 50-9. |
| Wintermeyer P, Wands JR. "Vaccines to prevent chronic hepatitis C virus infection: current experimental and preclinical developments." Journal of gastroenterology, vol. 42, no. 6, 2007, pp. 424-32. |
| Bengochea, A., De Souza, M., Lefrancois, L., Trepo, C., Kim, M., Wands, J.R., Hainaut, P., Scoazec, J.Y., Vitvitski, L., Merle, P. "347 Overexpression of the Wnt/frizzled signal's members: A common and early event in human hepatocellular carcinoma (HCC)." Journal of Hepatology, vol. 44, 2006, pp. S133. |
|
Hamilton, Theron J., Cao, Guohua, Wang, Shougang, Bailat, Claude J., Nguyen, Cuong K., Li, Shengqiong, Gehring, Stephan, Wands, Jack, Gusev, Vitalyi, Rose-Petruck, Christoph, Diebold, Gerald J.
" |
| Brown LA, Cook RT, Jerrells TR, Kolls JK, Nagy LE, Szabo G, Wands JR, Kovacs EJ. "Acute and chronic alcohol abuse modulate immunity." Alcoholism: Clinical and Experimental Research, vol. 30, no. 9, 2006, pp. 1624-31. |
| de la Monte SM, Tamaki S, Cantarini MC, Ince N, Wiedmann M, Carter JJ, Lahousse SA, Califano S, Maeda T, Ueno T, D'Errico A, Trevisani F, Wands JR. "Aspartyl-(asparaginyl)-beta-hydroxylase regulates hepatocellular carcinoma invasiveness." Journal of Hepatology, vol. 44, no. 5, 2006, pp. 971-83. |
| Cantarini MC, de la Monte SM, Pang M, Tong M, D'Errico A, Trevisani F, Wands JR. "Aspartyl-asparagyl beta hydroxylase over-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms." Hepatology, vol. 44, no. 2, 2006, pp. 446-57. |
| Fu X, Beer DG, Behar J, Wands J, Lambeth D, Cao W. "cAMP-response element-binding protein mediates acid-induced NADPH oxidase NOX5-S expression in Barrett esophageal adenocarcinoma cells." Journal of Biological Chemistry, vol. 281, no. 29, 2006, pp. 20368-82. |
| Soscia SJ, Tong M, Xu XJ, Cohen AC, Chu J, Wands JR, de la Monte SM. "Chronic gestational exposure to ethanol causes insulin and IGF resistance and impairs acetylcholine homeostasis in the brain." Cellular and molecular life sciences : CMLS, vol. 63, no. 17, 2006, pp. 2039-56. |
| Lahousse SA, Carter JJ, Xu XJ, Wands JR, de la Monte SM. "Differential growth factor regulation of aspartyl-(asparaginyl)-beta-hydroxylase family genes in SH-Sy5y human neuroblastoma cells." BMC cell biology, vol. 7, 2006, pp. 41. |
| Encke J, Geissler M, Stremmel W, Wands JR. "DNA-based immunization breaks tolerance in a hepatitis C virus transgenic mouse model." Human vaccines, vol. 2, no. 2, 2006, pp. 78-83. |
| Derdák Z, Fülöp P, Sabo E, Tavares R, Berthiaume EP, Resnick MB, Paragh G, Wands JR, Baffy G. "Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with NF-kappaB activation and oxidative stress." Carcinogenesis, vol. 27, no. 5, 2006, pp. 956-61. |
| Szabo G, Aloman C, Polyak SJ, Weinman SA, Wands J, Zakhari S. "Hepatitis C infection and alcohol use: A dangerous mix for the liver and antiviral immunity." Alcoholism: Clinical and Experimental Research, vol. 30, no. 4, 2006, pp. 709-19. |
| Tanaka S, Wands JR, Arii S. "Induction of angiopoietin-2 gene expression by COX-2: a novel role for COX-2 inhibitors during hepatocarcinogenesis." Journal of Hepatology, vol. 44, no. 1, 2006, pp. 233-5. |
| Lester-Coll N, Rivera EJ, Soscia SJ, Doiron K, Wands JR, de la Monte SM. "Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease." Journal of Alzheimer's disease : JAD, vol. 9, no. 1, 2006, pp. 13-33. |
| Fülöp P, Derdák Z, Sheets A, Sabo E, Berthiaume EP, Resnick MB, Wands JR, Paragh G, Baffy G. "Lack of UCP2 reduces Fas-mediated liver injury in ob/ob mice and reveals importance of cell-specific UCP2 expression." Hepatology, vol. 44, no. 3, 2006, pp. 592-601. |
| Lee HC, Tian B, Sedivy JM, Wands JR, Kim M. "Loss of Raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells." Gastroenterology, vol. 131, no. 4, 2006, pp. 1208-17. |
| de la Monte SM, Wands JR. "Molecular indices of oxidative stress and mitochondrial dysfunction occur early and often progress with severity of Alzheimer's disease." Journal of Alzheimer's disease : JAD, vol. 9, no. 2, 2006, pp. 167-81. |
| Wands, J.R., Merle, P., de la Monte, S., Kim, M., Herrmann, M., Tanaka, S., Von Dem Bussche, A., Kew, M.C., Trépo, C. "O.084 Role of frizzled-7 receptor overexpression in HBV and HCV related human hepatocellular carcinoma." Journal of Clinical Virology, vol. 36, 2006, pp. S25. |
| Bengochéa, A., De Souza, M.M., Lefrançois, L., Trépo, C., Kim, M., Wands, J.R., Hainaut, P., Scoazec, J.Y., Vitvitski, L., Merle, P. "O.085 Overexpression of the Wnt/Frizzled signal's memebers: A strikingly common and early event in human hepatocellular carcinoma (HCC)." Journal of Clinical Virology, vol. 36, 2006, pp. S25-S26. |
| Tong, S., Zoulim, F., Li, J., Wands, J., Trépo, C. "O.165 Naturally occurring mutations that regulate hepatitis B e antigen expression." Journal of Clinical Virology, vol. 36, 2006, pp. S51. |
| de la Monte, Suzanne M., Tong, Ming, Lester-Coll, Nataniel, Wands, Jack R. "O3-02-01." Alzheimer's & Dementia, vol. 2, no. 3, 2006, pp. S53-S54. |
| Kim, K., Tang, X., Gewaily, D., Li, J., Wands, J., Tong, S. "P.018 Opposing effects of two naturally occurring mutations in hepatitis B virus core protein on 2nd strand DNA synthesis." Journal of Clinical Virology, vol. 36, 2006, pp. S66-S67. |
| Kwei, K., Tang, X., Konkin, T., Li, J., Wands, J., Tong, S. "P.054 Hepatitis B virus vaccine escape mutants may have defects in virion secretion." Journal of Clinical Virology, vol. 36, 2006, pp. S77. |
| Von dem Bussche, A., Li, K., Dumoulin, F., Zhou, Y., Wands, J., Li, J. "P.178 Activation of endoplasmic reticulum stress signaling by the hepatitis C virus NS2 protein in the context of HCV replication." Journal of Clinical Virology, vol. 36, 2006, pp. S115-S116. |
| Guarnieri M, Kim KH, Bang G, Li J, Zhou Y, Tang X, Wands J, Tong S. "Point mutations upstream of hepatitis B virus core gene affect DNA replication at the step of core protein expression." Journal of Virology, vol. 80, no. 2, 2006, pp. 587-95. |
| Branda M, Wands JR. "Signal transduction cascades and hepatitis B and C related hepatocellular carcinoma." Hepatology, vol. 43, no. 5, 2006, pp. 891-902. |
| de la Monte SM, Tong M, Lester-Coll N, Plater M Jr, Wands JR. "Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease." Journal of Alzheimer's disease : JAD, vol. 10, no. 1, 2006, pp. 89-109. |
| Hamilton, T.J., Cuohua Cao, None, Bailat, C.J., Wands, J., Gehring, S., Rose-Petruck, C., Diebold, G.J. "Ultrasonically Modulated X-Ray Phase Contrast Imaging." 3rd IEEE International Symposium on Biomedical Imaging: Macro to Nano, 2006., 2006. |
| Kuzushita N, Gregory SH, Monti NA, Carlson R, Gehring S, Wands JR. "Vaccination with protein-transduced dendritic cells elicits a sustained response to hepatitis C viral antigens." Gastroenterology, vol. 130, no. 2, 2006, pp. 453-64. |
| Lee HC, Kim M, Wands JR. "Wnt/Frizzled signaling in hepatocellular carcinoma." Frontiers in Bioscience, vol. 11, 2006, pp. 1901-15. |
| Bang G, Kim KH, Guarnieri M, Zoulim F, Kawai S, Li J, Wands J, Tong S. "Effect of mutating the two cysteines required for HBe antigenicity on hepatitis B virus DNA replication and virion secretion." Virology, vol. 332, no. 1, 2005, pp. 216-24. |
| de la Monte SM, Xu XJ, Wands JR. "Ethanol inhibits insulin expression and actions in the developing brain." Cellular and molecular life sciences : CMLS, vol. 62, no. 10, 2005, pp. 1131-45. |
| Tong S, Kim KH, Chante C, Wands J, Li J. "Hepatitis B Virus e Antigen Variants." International Journal of Medical Sciences, vol. 2, no. 1, 2005, pp. 2-7. |
| Fukutomi T, Zhou Y, Kawai S, Eguchi H, Wands JR, Li J. "Hepatitis C virus core protein stimulates hepatocyte growth: correlation with upregulation of wnt-1 expression." Hepatology, vol. 41, no. 5, 2005, pp. 1096-105. |
| Steen E, Terry BM, Rivera EJ, Cannon JL, Neely TR, Tavares R, Xu XJ, Wands JR, de la Monte SM. "Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?." Journal of Alzheimer's disease : JAD, vol. 7, no. 1, 2005, pp. 63-80. |
| Rivera EJ, Goldin A, Fulmer N, Tavares R, Wands JR, de la Monte SM. "Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine." Journal of Alzheimer's disease : JAD, vol. 8, no. 3, 2005, pp. 247-68. |
| Merle P, Kim M, Herrmann M, Gupte A, Lefrançois L, Califano S, Trépo C, Tanaka S, Vitvitski L, de la Monte S, Wands JR. "Oncogenic role of the frizzled-7/beta-catenin pathway in hepatocellular carcinoma." Journal of Hepatology, vol. 43, no. 5, 2005, pp. 854-62. |
| de la Monte SM, Wands JR. "Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease." Journal of Alzheimer's disease : JAD, vol. 7, no. 1, 2005, pp. 45-61. |
| Gehring S, Gregory SH, Kuzushita N, Wands JR. "Type 1 interferon augments DNA-based vaccination against hepatitis C virus core protein." Journal of medical virology, vol. 75, no. 2, 2005, pp. 249-57. |
| Merle, P., De La Monte, S., Herrmann, M., Tanaka, S., Kew, M.C., Kim, M., Trepo, C., Wands, J.R. "47 Role of frizzled-7 receptor in human hepatocarcinogenesis." Journal of Hepatology, vol. 40, 2004, pp. 17-18. |
| de la Monte SM, Wands JR. "Alzheimer-associated neuronal thread protein mediated cell death is linked to impaired insulin signaling." Journal of Alzheimer's disease : JAD, vol. 6, no. 3, 2004, pp. 231-42. |
| Mohr L, Yeung A, Aloman C, Wittrup D, Wands JR. "Antibody-directed therapy for human hepatocellular carcinoma." Gastroenterology, vol. 127, no. 5 Suppl 1, 2004, pp. S225-31. |
| Maeda T, Taguchi K, Aishima S, Shimada M, Hintz D, Larusso N, Gores G, Tsuneyoshi M, Sugimachi K, Wands JR, de la Monte SM. "Clinicopathological correlates of aspartyl (asparaginyl) beta-hydroxylase over-expression in cholangiocarcinoma." Cancer Detection and Prevention, vol. 28, no. 5, 2004, pp. 313-8. |
| Horimoto M, Resnick MB, Konkin TA, Routhier J, Wands JR, Baffy G. "Expression of uncoupling protein-2 in human colon cancer." Clin Cancer Res , vol. 10, no. 18 Pt 1, 2004, pp. 6203-7. |
| Merle P, de la Monte S, Kim M, Herrmann M, Tanaka S, Von Dem Bussche A, Kew MC, Trepo C, Wands JR. "Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma." Gastroenterology, vol. 127, no. 4, 2004, pp. 1110-22. |
| Li J, Tong S, Lee HB, Perdigoto AL, Spangenberg HC, Wands JR. "Glycine decarboxylase mediates a postbinding step in duck hepatitis B virus infection." Journal of Virology, vol. 78, no. 4, 2004, pp. 1873-81. |
| Khan N, Guarnieri M, Ahn SH, Li J, Zhou Y, Bang G, Kim KH, Wands JR, Tong S. "Modulation of hepatitis B virus secretion by naturally occurring mutations in the S gene." Journal of Virology, vol. 78, no. 7, 2004, pp. 3262-70. |
| Wands JR. "Prevention of hepatocellular carcinoma." New England Journal of Medicine, vol. 351, no. 15, 2004, pp. 1567-70. |
| Giannone PJ, Abu Dayyeh BK, Bienieki TC, Wands JR, Gruppuso PA. "Targeted hepatic overexpression of human IRS-1: postnatal effects in the developing mouse." Biochimica et biophysica acta, vol. 1672, no. 2, 2004, pp. 112-9. |
| Yoon SK, Lim NK, Ha SA, Park YG, Choi JY, Chung KW, Sun HS, Choi MJ, Chung J, Wands JR, Kim JW. "The human cervical cancer oncogene protein is a biomarker for human hepatocellular carcinoma." Cancer Research, vol. 64, no. 15, 2004, pp. 5434-41. |
| Berthiaume EP, Wands J. "The molecular pathogenesis of cholangiocarcinoma." Seminars in liver disease, vol. 24, no. 2, 2004, pp. 127-37. |
| Horimoto M, Fülöp P, Derdák Z, Wands JR, Baffy G. "Uncoupling protein-2 deficiency promotes oxidant stress and delays liver regeneration in mice." Hepatology, vol. 39, no. 2, 2004, pp. 386-92. |
| Tanaka S, Sugimachi K, Yamashita Y, Shirabe K, Shimada M, Wands JR, Sugimachi K. "Angiogenic switch as a molecular target of malignant tumors." Journal of gastroenterology, vol. 38 Suppl 15, 2003, pp. 93-7. |
| Maeda T, Sepe P, Lahousse S, Tamaki S, Enjoji M, Wands JR, de la Monte SM. "Antisense oligodeoxynucleotides directed against aspartyl (asparaginyl) beta-hydroxylase suppress migration of cholangiocarcinoma cells." Journal of Hepatology, vol. 38, no. 5, 2003, pp. 615-22. |
| Wiedmann M, Tamaki S, Silberman R, de la Monte SM, Cousens L, Wands JR. "Constitutive over-expression of the insulin receptor substrate-1 causes functional up-regulation of Fas receptor." Journal of Hepatology, vol. 38, no. 6, 2003, pp. 803-10. |
| Encke J, zu Putlitz J, Stremmel W, Wands JR. "CpG immuno-stimulatory motifs enhance humoral immune responses against hepatitis C virus core protein after DNA-based immunization." Archives of virology, vol. 148, no. 3, 2003, pp. 435-48. |
| Xu J, Yeon JE, Chang H, Tison G, Chen GJ, Wands J, de la Monte S. "Ethanol impairs insulin-stimulated neuronal survival in the developing brain: role of PTEN phosphatase." Journal of Biological Chemistry, vol. 278, no. 29, 2003, pp. 26929-37. |
| Parekh S, Zoulim F, Ahn SH, Tsai A, Li J, Kawai S, Khan N, Trépo C, Wands J, Tong S. "Genome replication, virion secretion, and e antigen expression of naturally occurring hepatitis B virus core promoter mutants." Journal of Virology, vol. 77, no. 12, 2003, pp. 6601-12. |
| dem Bussche, A von, Dumoulin, FL, Merle, P, Sauerbruch, T, Spengler, U, Wands, JR, Li, JS. "Hepatitis C Virus NS2 Protein hemmt die Transkription viraler und endogener zellulärer Gene in humanen Hepatomzellen." Z Gastroenterol, vol. 41, no. 08, 2003. |
| Dumoulin FL, von dem Bussche A, Li J, Khamzina L, Wands JR, Sauerbruch T, Spengler U. "Hepatitis C virus NS2 protein inhibits gene expression from different cellular and viral promoters in hepatic and nonhepatic cell lines." Virology, vol. 305, no. 2, 2003, pp. 260-6. |
| Tanaka S, Sugimachi K, Kameyama T, Maehara S, Shirabe K, Shimada M, Wands JR, Maehara Y. "Human WISP1v, a member of the CCN family, is associated with invasive cholangiocarcinoma." Hepatology, vol. 37, no. 5, 2003, pp. 1122-9. |
| Khamzina L, Gruppuso PA, Wands JR. "Insulin signaling through insulin receptor substrate 1 and 2 in normal liver development." Gastroenterology, vol. 125, no. 2, 2003, pp. 572-85. |
| Iyoda K, Sasaki Y, Horimoto M, Toyama T, Yakushijin T, Sakakibara M, Takehara T, Fujimoto J, Hori M, Wands JR, Hayashi N. "Involvement of the p38 mitogen-activated protein kinase cascade in hepatocellular carcinoma." Cancer, vol. 97, no. 12, 2003, pp. 3017-26. |
| Molina PE, Hoek JB, Nelson S, Guidot DM, Lang CH, Wands JR, Crawford JM. "Mechanisms of alcohol-induced tissue injury." Alcoholism: Clinical and Experimental Research, vol. 27, no. 3, 2003, pp. 563-75. |
| de la Monte SM, Chen GJ, Rivera E, Wands JR. "Neuronal thread protein regulation and interaction with microtubule-associated proteins in SH-Sy5y neuronal cells." Cellular and molecular life sciences : CMLS, vol. 60, no. 12, 2003, pp. 2679-91. |
| Yeon JE, Califano S, Xu J, Wands JR, De La Monte SM. "Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liver." Hepatology, vol. 38, no. 3, 2003, pp. 703-14. |
| Aloman C, Wands JR. "Resistance of HBV to adefovir dipivoxil: a case for combination antiviral therapy?." Hepatology, vol. 38, no. 6, 2003, pp. 1584-7. |
| Ahn SH, Kramvis A, Kawai S, Spangenberg HC, Li J, Kimbi G, Kew M, Wands J, Tong S. "Sequence variation upstream of precore translation initiation codon reduces hepatitis B virus e antigen production." Gastroenterology, vol. 125, no. 5, 2003, pp. 1370-8. |
| de la Monte SM, Lahousse SA, Carter J, Wands JR. "ATP luminescence-based motility-invasion assay." BioTechniques, vol. 33, no. 1, 2002, pp. 98-100, 102, 104 passim. |
| de la Monte SM, Wands JR. "Chronic gestational exposure to ethanol impairs insulin-stimulated survival and mitochondrial function in cerebellar neurons." Cellular and molecular life sciences : CMLS, vol. 59, no. 5, 2002, pp. 882-93. |
| Palumbo KS, Wands JR, Safran H, King T, Carlson RI, de la Monte SM. "Human aspartyl (asparaginyl) beta-hydroxylase monoclonal antibodies: potential biomarkers for pancreatic carcinoma." Pancreas, vol. 25, no. 1, 2002, pp. 39-44. |
| Tanaka S, Sugimachi K, Maehara S, Harimoto N, Shirabe K, Wands JR, Sugimachi K. "Oncogenic signal transduction and therapeutic strategy for hepatocellular carcinoma." Surgery, vol. 131, no. 1 Suppl, 2002, pp. S142-7. |
| Sepe PS, Lahousse SA, Gemelli B, Chang H, Maeda T, Wands JR, de la Monte SM. "Role of the aspartyl-asparaginyl-beta-hydroxylase gene in neuroblastoma cell motility." Laboratory investigation; a journal of technical methods and pathology, vol. 82, no. 7, 2002, pp. 881-91. |
| de la Monte SM, Wands JR. "The AD7c-ntp neuronal thread protein biomarker for detecting Alzheimer's disease." Frontiers in Bioscience, vol. 7, 2002, pp. d989-96. |
| Tanaka S, Sugimachi K, Yamashita Yi Y, Ohga T, Shirabe K, Shimada M, Wands JR, Sugimachi K. "Tie2 vascular endothelial receptor expression and function in hepatocellular carcinoma." Hepatology, vol. 35, no. 4, 2002, pp. 861-7. |
| Tanaka S, Ueo H, Mafune K, Mori M, Wands JR, Sugimachi K. "A novel isoform of human fibroblast growth factor 8 is induced by androgens and associated with progression of esophageal carcinoma." Digestive Diseases and Sciences, vol. 46, no. 5, 2001, pp. 1016-21. |
| Spangenberg HC, Lee HB, Li J, Tan F, Skidgel R, Wands JR, Tong S. "A short sequence within domain C of duck carboxypeptidase D is critical for duck hepatitis B virus binding and determines host specificity." Journal of Virology, vol. 75, no. 22, 2001, pp. 10630-42. |
| Yoon SK, Armentano D, Wands JR, Mohr L. "Adenovirus-mediated gene transfer to orthotopic hepatocellular carcinomas in athymic nude mice." Cancer gene therapy, vol. 8, no. 8, 2001, pp. 573-9. |
| de la Monte SM, Wands JR. "Alzheimer-associated neuronal thread protein-induced apoptosis and impaired mitochondrial function in human central nervous system-derived neuronal cells." Journal of Neuropathology and Experimental Neurology, vol. 60, no. 2, 2001, pp. 195-207. |
| Mohr L, Yoon SK, Eastman SJ, Chu Q, Scheule RK, Scaglioni PP, Geissler M, Heintges T, Blum HE, Wands JR. "Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice." Human gene therapy, vol. 12, no. 7, 2001, pp. 799-809. |
| de la Monte SM, Neely TR, Cannon J, Wands JR. "Ethanol impairs insulin-stimulated mitochondrial function in cerebellar granule neurons." Cellular and molecular life sciences : CMLS, vol. 58, no. 12-13, 2001, pp. 1950-60. |
| Mauch C, Grimm C, Meckel S, Wands JR, Blum HE, Roggendorf M, Geissler M. "Induction of cytotoxic T lymphocyte responses against hepatitis delta virus antigens which protect against tumor formation in mice." Vaccine, vol. 20, no. 1-2, 2001, pp. 170-80. |
| Heintges T, Encke J, zu Putlitz J, Wands JR. "Inhibition of hepatitis C virus NS3 function by antisense oligodeoxynucleotides and protease inhibitor." Journal of medical virology, vol. 65, no. 4, 2001, pp. 671-80. |
| Krohne TU, Shankara S, Geissler M, Roberts BL, Wands JR, Blum HE, Mohr L. "Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitro." Hepatology, vol. 34, no. 3, 2001, pp. 511-8. |
| de La Monte SM, Wands JR. "Mitochondrial dna damage and impaired mitochondrial function contribute to apoptosis of insulin-stimulated ethanol-exposed neuronal cells." Alcoholism: Clinical and Experimental Research, vol. 25, no. 6, 2001, pp. 898-906. |
| de la Monte SM, Wands JR. "Neurodegeneration changes in primary central nervous system neurons transfected with the Alzheimer-associated neuronal thread protein gene." Cellular and molecular life sciences : CMLS, vol. 58, no. 5-6, 2001, pp. 844-9. |
| Spangenberg HC, Wands JR. "Ribozymes and hepatitis B virus." Journal of gastroenterology and hepatology, vol. 16, no. 10, 2001, pp. 1084-5. |
| De La Monte SM, Wands JR. "The AD7c-NTP neuronal thread protein biomarker for detecting Alzheimer's disease." Journal of Alzheimer's disease : JAD, vol. 3, no. 3, 2001, pp. 345-353. |
| de la Monte SM, Lu BX, Sohn YK, Etienne D, Kraft J, Ganju N, Wands JR. "Aberrant expression of nitric oxide synthase III in Alzheimer's disease: relevance to cerebral vasculopathy and neurodegeneration." Neurobiology of aging, vol. 21, no. 2, 2000, pp. 309-19. |
| zu Putlitz J, Encke J, Wands JR. "Cytotoxic T cell responses against hepatitis B virus polymerase induced by genetic immunization." Journal of Hepatology, vol. 33, no. 6, 2000, pp. 986-91. |
| Encke J, Wands JR. "Ethanol inhibition: the humoral and cellular immune response to hepatitis C virus NS5 protein after genetic immunization." Alcoholism: Clinical and Experimental Research, vol. 24, no. 7, 2000, pp. 1063-9. |
| Tanaka S, Sugimachi K, Shirabe K, Shimada M, Wands JR. "Expression and antitumor effects of TRAIL in human cholangiocarcinoma." Hepatology, vol. 32, no. 3, 2000, pp. 523-7. |
| Mohr L, Shankara S, Yoon SK, Krohne TU, Geissler M, Roberts B, Blum HE, Wands JR. "Gene therapy of hepatocellular carcinoma in vitro and in vivo in nude mice by adenoviral transfer of the Escherichia coli purine nucleoside phosphorylase gene." Hepatology, vol. 31, no. 3, 2000, pp. 606-14. |
| Tanaka S, Sugimachi K, Kawaguchi H, Saeki H, Ohno S, Wands JR. "Grb7 signal transduction protein mediates metastatic progression of esophageal carcinoma." Journal of cellular physiology, vol. 183, no. 3, 2000, pp. 411-5. |
| de la Monte SM, Luong T, Neely TR, Robinson D, Wands JR. "Mitochondrial DNA damage as a mechanism of cell loss in Alzheimer's disease." Laboratory investigation; a journal of technical methods and pathology, vol. 80, no. 8, 2000, pp. 1323-35. |
| Ince N, de la Monte SM, Wands JR. "Overexpression of human aspartyl (asparaginyl) beta-hydroxylase is associated with malignant transformation." Cancer Research, vol. 60, no. 5, 2000, pp. 1261-6. |
| de la Monte SM, Neely TR, Cannon J, Wands JR. "Oxidative stress and hypoxia-like injury cause Alzheimer-type molecular abnormalities in central nervous system neurons." Cellular and molecular life sciences : CMLS, vol. 57, no. 10, 2000, pp. 1471-81. |
| de la Monte SM, Ganju N, Feroz N, Luong T, Banerjee K, Cannon J, Wands JR. "Oxygen free radical injury is sufficient to cause some Alzheimer-type molecular abnormalities in human CNS neuronal cells." Journal of Alzheimer's disease : JAD, vol. 2, no. 3-4, 2000, pp. 261-81. |
| de la Monte SM, Ganju N, Banerjee K, Brown NV, Luong T, Wands JR. "Partial rescue of ethanol-induced neuronal apoptosis by growth factor activation of phosphoinositol-3-kinase." Alcoholism: Clinical and Experimental Research, vol. 24, no. 5, 2000, pp. 716-26. |
| Mohr L, Rainov NG, Mohr UG, Wands JR. "Rabbit cytochrome P450 4B1: A novel prodrug activating gene for pharmacogene therapy of hepatocellular carcinoma." Cancer gene therapy, vol. 7, no. 7, 2000, pp. 1008-14. |
| de la Monte SM, Sohn YK, Etienne D, Kraft J, Wands JR. "Role of aberrant nitric oxide synthase-3 expression in cerebrovascular degeneration and vascular-mediated injury in Alzheimer's disease." Annals of the New York Academy of Sciences, vol. 903, 2000, pp. 61-71. |
| Yoon SK, Mohr L, O'Riordan CR, Lachapelle A, Armentano D, Wands JR. "Targeting a recombinant adenovirus vector to HCC cells using a bifunctional Fab-antibody conjugate." Biochemical and Biophysical Research Communications, vol. 272, no. 2, 2000, pp. 497-504. |
| zu Putlitz J, Tong S, Wands JR. "A short region in the genome of hepatitis B virus is critical for maintenance of high transcript levels." Virology, vol. 254, no. 2, 1999, pp. 245-56. |
| Wakita T, Moradpour D, Tokushihge K, Wands JR. "Antiviral effects of antisense RNA on hepatitis C virus RNA translation and expression." Journal of medical virology, vol. 57, no. 3, 1999, pp. 217-22. |
| Tanaka S, Mori M, Sakamoto Y, Makuuchi M, Sugimachi K, Wands JR. "Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma." Journal of Clinical Investigation, vol. 103, no. 3, 1999, pp. 341-5. |
| Tong S, Li J, Wands JR. "Carboxypeptidase D is an avian hepatitis B virus receptor." Journal of Virology, vol. 73, no. 10, 1999, pp. 8696-702. |
| Heintges T, zu Putlitz J, Wands JR. "Characterization and binding of intracellular antibody fragments to the hepatitis C virus core protein." Biochemical and Biophysical Research Communications, vol. 263, no. 2, 1999, pp. 410-8. |
| zu Putlitz J, Yu Q, Burke JM, Wands JR. "Combinatorial screening and intracellular antiviral activity of hairpin ribozymes directed against hepatitis B virus." Journal of Virology, vol. 73, no. 7, 1999, pp. 5381-7. |
| de la Monte SM, Ganju N, Tanaka S, Banerjee K, Karl PJ, Brown NV, Wands JR. "Differential effects of ethanol on insulin-signaling through the insulin receptor substrate-1." Alcoholism: Clinical and Experimental Research, vol. 23, no. 5, 1999, pp. 770-7. |
| Encke J, zu Putlitz J, Wands JR. "DNA vaccines." Intervirology, vol. 42, no. 2-3, 1999, pp. 117-24. |
| Li J, Tong S, Wands JR. "Identification and expression of glycine decarboxylase (p120) as a duck hepatitis B virus pre-S envelope-binding protein." Journal of Biological Chemistry, vol. 274, no. 39, 1999, pp. 27658-65. |
| zu Putlitz J, Skerra A, Wands JR. "Intracellular expression of a cloned antibody fragment interferes with hepatitis B virus surface antigen secretion." Biochemical and Biophysical Research Communications, vol. 255, no. 3, 1999, pp. 785-91. |
| Geissler M, Bruss V, Michalak S, Hockenjos B, Ortmann D, Offensperger WB, Wands JR, Blum HE. "Intracellular retention of hepatitis B virus surface proteins reduces interleukin-2 augmentation after genetic immunizations." Journal of Virology, vol. 73, no. 5, 1999, pp. 4284-92. |
| de la Monte SM, Ganju N, Wands JR. "Microtiter immunocytochemical ELISA assay." BioTechniques, vol. 26, no. 6, 1999, pp. 1073-6, 1078. |
| Sohn YK, Ganju N, Bloch KD, Wands JR, de la Monte SM. "Neuritic sprouting with aberrant expression of the nitric oxide synthase III gene in neurodegenerative diseases." Journal of the Neurological Sciences, vol. 162, no. 2, 1999, pp. 133-51. |
| zu Putlitz J, Lanford RE, Carlson RI, Notvall L, de la Monte SM, Wands JR. "Properties of monoclonal antibodies directed against hepatitis B virus polymerase protein." Journal of Virology, vol. 73, no. 5, 1999, pp. 4188-96. |
| zu Putlitz J, Wands JR. "Specific inhibition of hepatitis B virus replication by sense RNA." Antisense & nucleic acid drug development, vol. 9, no. 3, 1999, pp. 241-52. |
| Mohr L, Schauer JI, Boutin RH, Moradpour D, Wands JR. "Targeted gene transfer to hepatocellular carcinoma cells in vitro using a novel monoclonal antibody-based gene delivery system." Hepatology, vol. 29, no. 1, 1999, pp. 82-9. |
| Ince N, Wands JR. "The increasing incidence of hepatocellular carcinoma." New England Journal of Medicine, vol. 340, no. 10, 1999, pp. 798-9. |
| Tanaka S, Akiyoshi T, Mori M, Wands JR, Sugimachi K. "A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals." Proceedings of the National Academy of Sciences, vol. 95, no. 17, 1998, pp. 10164-9. |
| Tanaka S, Mori M, Akiyoshi T, Tanaka Y, Mafune K, Wands JR, Sugimachi K. "A novel variant of human Grb7 is associated with invasive esophageal carcinoma." Journal of Clinical Investigation, vol. 102, no. 4, 1998, pp. 821-7. |
| zu Putlitz J, Wieland S, Blum HE, Wands JR. "Antisense RNA complementary to hepatitis B virus specifically inhibits viral replication." Gastroenterology, vol. 115, no. 3, 1998, pp. 702-13. |
| Etiene D, Kraft J, Ganju N, Gomez-Isla T, Gemelli B, Hyman BT, Hedley-Whyte ET, Wands JR, De La Monte SM. "Cerebrovascular Pathology Contributes to the Heterogeneity of Alzheimer's Disease." Journal of Alzheimer's disease : JAD, vol. 1, no. 2, 1998, pp. 119-134. |
| Melegari M, Scaglioni PP, Wands JR. "Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication." Journal of Virology, vol. 72, no. 3, 1998, pp. 1737-43. |
| zu Putlitz J, Skerra A, Schröder CH, Zentgraf H, Wands JR. "Cloning, bacterial synthesis, and characterization of immunoglobulin variable regions of a monoclonal antibody specific for the hepatitis B virus X protein." Gene, vol. 221, no. 1, 1998, pp. 143-9. |
| Geissler M, Schirmbeck R, Reimann J, Blum HE, Wands JR. "Cytokine and hepatitis B virus DNA co-immunizations enhance cellular and humoral immune responses to the middle but not to the large hepatitis B virus surface antigen in mice." Hepatology, vol. 28, no. 1, 1998, pp. 202-10. |
| Geissler M, Tokushige K, Wakita T, Zurawski VR Jr, Wands JR. "Differential cellular and humoral immune responses to HCV core and HBV envelope proteins after genetic immunizations using chimeric constructs." Vaccine, vol. 16, no. 8, 1998, pp. 857-67. |
| Banerjee K, Mohr L, Wands JR, de la Monte SM. "Ethanol inhibition of insulin signaling in hepatocellular carcinoma cells." Alcoholism: Clinical and Experimental Research, vol. 22, no. 9, 1998, pp. 2093-101. |
| Mohr L, Tanaka S, Wands JR. "Ethanol inhibits hepatocyte proliferation in insulin receptor substrate 1 transgenic mice." Gastroenterology, vol. 115, no. 6, 1998, pp. 1558-65. |
| Encke J, zu Putlitz J, Geissler M, Wands JR. "Genetic immunization generates cellular and humoral immune responses against the nonstructural proteins of the hepatitis C virus in a murine model." The Journal of Immunology, vol. 161, no. 9, 1998, pp. 4917-23. |
| Melegari M, Scaglioni PP, Wands JR. "Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective." Hepatology, vol. 27, no. 2, 1998, pp. 628-33. |
| de la Monte SM, Sohn YK, Ganju N, Wands JR. "P53- and CD95-associated apoptosis in neurodegenerative diseases." Laboratory investigation; a journal of technical methods and pathology, vol. 78, no. 4, 1998, pp. 401-11. |
| Yasui K, Wakita T, Tsukiyama-Kohara K, Funahashi SI, Ichikawa M, Kajita T, Moradpour D, Wands JR, Kohara M. "The native form and maturation process of hepatitis C virus core protein." Journal of Virology, vol. 72, no. 7, 1998, pp. 6048-55. |
| Moradpour D, Wakita T, Wands JR, Blum HE. "Tightly regulated expression of the entire hepatitis C virus structural region in continuous human cell lines." Biochemical and Biophysical Research Communications, vol. 246, no. 3, 1998, pp. 920-4. |
| Encke J, zu Putlitz J, Heintges T, Wands JR. "Total chemical synthesis of the 3' untranslated region of the hepatitis C virus with long oligodeoxynucleotides." Journal of virological methods, vol. 74, no. 1, 1998, pp. 117-21. |
| Scaglioni PP, Melegari M, Wands JR. "Biologic properties of hepatitis B viral genomes with mutations in the precore promoter and precore open reading frame." Virology, vol. 233, no. 2, 1997, pp. 374-81. |
| Tanaka S, Mohr L, Schmidt EV, Sugimachi K, Wands JR. "Biological effects of human insulin receptor substrate-1 overexpression in hepatocytes." Hepatology, vol. 26, no. 3, 1997, pp. 598-604. |
| Geissler M, Tokushige K, Chante CC, Zurawski VR Jr, Wands JR. "Cellular and humoral immune response to hepatitis B virus structural proteins in mice after DNA-based immunization." Gastroenterology, vol. 112, no. 4, 1997, pp. 1307-20. |
| Monte SM, Ghanbari K, Frey WH, Beheshti I, Averback P, Hauser SL, Ghanbari HA, Wands JR. "Characterization of the AD7C-NTP cDNA expression in Alzheimer's disease and measurement of a 41-kD protein in cerebrospinal fluid." Journal of Clinical Investigation, vol. 100, no. 12, 1997, pp. 3093-104. |
| Geissler M, Gesien A, Wands JR. "Chronic ethanol effects on cellular immune responses to hepatitis B virus envelope protein: an immunologic mechanism for induction of persistent viral infection in alcoholics." Hepatology, vol. 26, no. 3, 1997, pp. 764-70. |
| Tanaka S, Mori M, Akiyoshi T, Tanaka Y, Mafune K, Wands JR, Sugimachi K. "Coexpression of Grb7 with epidermal growth factor receptor or Her2/erbB2 in human advanced esophageal carcinoma." Cancer Research, vol. 57, no. 1, 1997, pp. 28-31. |
| Tokushige K, Moradpour D, Wakita T, Geissler M, Hayashi N, Wands JR. "Comparison between cytomegalovirus promoter and elongation factor-1 alpha promoter-driven constructs in the establishment of cell lines expressing hepatitis C virus core protein." Journal of virological methods, vol. 64, no. 1, 1997, pp. 73-80. |
| de la Monte SM, Sohn YK, Wands JR. "Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease." Journal of the Neurological Sciences, vol. 152, no. 1, 1997, pp. 73-83. |
| Geissler M, Gesien A, Tokushige K, Wands JR. "Enhancement of cellular and humoral immune responses to hepatitis C virus core protein using DNA-based vaccines augmented with cytokine-expressing plasmids." The Journal of Immunology, vol. 158, no. 3, 1997, pp. 1231-7. |
| Geissler M, Wands G, Gesien A, de la Monte S, Bellet D, Wands JR. "Genetic immunization with the free human chorionic gonadotropin beta subunit elicits cytotoxic T lymphocyte responses and protects against tumor formation in mice." Laboratory investigation; a journal of technical methods and pathology, vol. 76, no. 6, 1997, pp. 859-71. |
| Heintges T, Wands JR. "Hepatitis C virus: epidemiology and transmission." Hepatology, vol. 26, no. 3, 1997, pp. 521-6. |
| Wands JR, Lavaissiere L, Moradpour D, de la Monte S, Mohr L, Nicolau C, Tanaka S. "Immunological approach to hepatocellular carcinoma." Journal of viral hepatitis, vol. 4 Suppl 2, 1997, pp. 60-74. |
| Geissler M, Gesien A, Wands JR. "Inhibitory effects of chronic ethanol consumption on cellular immune responses to hepatitis C virus core protein are reversed by genetic immunizations augmented with cytokine-expressing plasmids." The Journal of Immunology, vol. 159, no. 10, 1997, pp. 5107-13. |
| de la Monte SM, Garner W, Wands JR. "Neuronal thread protein gene modulation with cerebral infarction." Journal of Cerebral Blood Flow & Metabolism, vol. 17, no. 6, 1997, pp. 623-35. |
| Wands JR, Geissler M, Putlitz JZ, Blum H, von Weizsäcker F, Mohr L, Yoon SK, Melegari M, Scaglioni PP. "Nucleic acid-based antiviral and gene therapy of chronic hepatitis B infection." Journal of gastroenterology and hepatology, vol. 12, no. 9-10, 1997, pp. S354-69. |
| Scaglioni PP, Melegari M, Wands JR. "Posttranscriptional regulation of hepatitis B virus replication by the precore protein." Journal of Virology, vol. 71, no. 1, 1997, pp. 345-53. |
| Melegari M, Scaglioni PP, Wands JR. "The small envelope protein is required for secretion of a naturally occurring hepatitis B virus mutant with pre-S1 deleted." Journal of Virology, vol. 71, no. 7, 1997, pp. 5449-54. |
| Tanaka S, Wands JR. "A carboxy-terminal truncated insulin receptor substrate-1 dominant negative protein reverses the human hepatocellular carcinoma malignant phenotype." Journal of Clinical Investigation, vol. 98, no. 9, 1996, pp. 2100-8. |
| Li JS, Tong SP, Wands JR. "Characterization of a 120-Kilodalton pre-S-binding protein as a candidate duck hepatitis B virus receptor." Journal of Virology, vol. 70, no. 9, 1996, pp. 6029-35. |
| Moradpour D, Englert C, Wakita T, Wands JR. "Characterization of cell lines allowing tightly regulated expression of hepatitis C virus core protein." Virology, vol. 222, no. 1, 1996, pp. 51-63. |
| Moradpour D, Wakita T, Tokushige K, Carlson RI, Krawczynski K, Wands JR. "Characterization of three novel monoclonal antibodies against hepatitis C virus core protein." Journal of medical virology, vol. 48, no. 3, 1996, pp. 234-41. |
| Yoshikawa H, de la Monte S, Nagai H, Wands JR, Matsubara K, Fujiyama A. "Chromosomal assignment of human genomic NotI restriction fragments in a two-dimensional electrophoresis profile." Genomics, vol. 31, no. 1, 1996, pp. 28-35. |
| de la Monte SM, Xu YY, Hutchins GM, Wands JR. "Developmental patterns of neuronal thread protein gene expression in Down syndrome." Journal of the Neurological Sciences, vol. 135, no. 2, 1996, pp. 118-25. |
| Moradpour D, Schauer JI, Zurawski VR Jr, Wands JR, Boutin RH. "Efficient gene transfer into mammalian cells with cholesteryl-spermidine." Biochemical and Biophysical Research Communications, vol. 221, no. 1, 1996, pp. 82-8. |
| Tokushige K, Wakita T, Pachuk C, Moradpour D, Weiner DB, Zurawski VR Jr, Wands JR. "Expression and immune response to hepatitis C virus core DNA-based vaccine constructs." Hepatology, vol. 24, no. 1, 1996, pp. 14-20. |
| Heller R, Jaroszeski M, Atkin A, Moradpour D, Gilbert R, Wands J, Nicolau C. "In vivo gene electroinjection and expression in rat liver." FEBS Letters, vol. 389, no. 3, 1996, pp. 225-8. |
| Tanaka S, Wands JR. "Insulin receptor substrate 1 overexpression in human hepatocellular carcinoma cells prevents transforming growth factor beta1-induced apoptosis." Cancer Research, vol. 56, no. 15, 1996, pp. 3391-4. |
| de la Monte SM, Xu YY, Wands JR. "Modulation of neuronal thread protein expression with neuritic sprouting: relevance to Alzheimer's disease." Journal of the Neurological Sciences, vol. 138, no. 1-2, 1996, pp. 26-35. |
| Tanaka S, Ito T, Wands JR. "Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules." Journal of Biological Chemistry, vol. 271, no. 24, 1996, pp. 14610-6. |
| Lavaissiere L, Jia S, Nishiyama M, de la Monte S, Stern AM, Wands JR, Friedman PA. "Overexpression of human aspartyl(asparaginyl)beta-hydroxylase in hepatocellular carcinoma and cholangiocarcinoma." Journal of Clinical Investigation, vol. 98, no. 6, 1996, pp. 1313-23. |
| Ito T, Sasaki Y, Wands JR. "Overexpression of human insulin receptor substrate 1 induces cellular transformation with activation of mitogen-activated protein kinases." Molecular and Cellular Biology, vol. 16, no. 3, 1996, pp. 943-51. |
| De La Monte SM, Carlson RI, Brown NV, Wands JR. "Profiles of neuronal thread protein expression in Alzheimer's disease." Journal of Neuropathology and Experimental Neurology, vol. 55, no. 10, 1996, pp. 1038-50. |
| Scaglioni PP, Melegari M, Wands JR. "Recent advances in the molecular biology of hepatitis B virus." Bailliere's clinical gastroenterology, vol. 10, no. 2, 1996, pp. 207-25. |
| Scaglioni P, Melegari M, Takahashi M, Chowdhury JR, Wands J. "Use of dominant negative mutants of the hepadnaviral core protein as antiviral agents." Hepatology, vol. 24, no. 5, 1996, pp. 1010-7. |
| Maia M, Takahashi H, Adler K, Garlick RK, Wands JR. "Development of a two-site immuno-PCR assay for hepatitis B surface antigen." Journal of virological methods, vol. 52, no. 3, 1995, pp. 273-86. |
| Bhavani K, de la Monte S, Brown NV, Xu YY, Sasaki Y, Wands JR. "Effect of ethanol on p36 protein kinase substrate and insulin receptor substrate 1 expression and tyrosyl phosphorylation in human hepatocellular carcinoma cells." Alcoholism: Clinical and Experimental Research, vol. 19, no. 2, 1995, pp. 441-6. |
| Xu YY, Bhavani K, Wands JR, de la Monte SM. "Ethanol inhibits insulin receptor substrate-1 tyrosine phosphorylation and insulin-stimulated neuronal thread protein gene expression." Biochem. J., vol. 310 ( Pt 1), 1995, pp. 125-32. |
| Takahashi H, Nakada T, Nakaki M, Wands JR. "Inhibition of hepatic metastases of human colon cancer in nude mice by a chimeric SF-25 monoclonal antibody." Gastroenterology, vol. 108, no. 1, 1995, pp. 172-82. |
| Xu YY, Bhavani K, Wands JR, de la Monte SM. "Insulin-induced differentiation and modulation of neuronal thread protein expression in primitive neuroectodermal tumor cells is linked to phosphorylation of insulin receptor substrate-1." Journal of molecular neuroscience : MN, vol. 6, no. 2, 1995, pp. 91-108. |
| Tong S, Li J, Wands JR. "Interaction between duck hepatitis B virus and a 170-kilodalton cellular protein is mediated through a neutralizing epitope of the pre-S region and occurs during viral infection." Journal of Virology, vol. 69, no. 11, 1995, pp. 7106-12. |
| Iwata K, Wakita T, Okumura A, Yoshioka K, Takayanagi M, Wands JR, Kakumu S. "Interferon gamma production by peripheral blood lymphocytes to hepatitis C virus core protein in chronic hepatitis C infection." Hepatology, vol. 22, no. 4 Pt 1, 1995, pp. 1057-64. |
| de la Monte SM, Bhavani K, Xu YY, Puisieux A, Wands JR. "Modulation of p36 gene expression in human neuronal cells." Journal of the Neurological Sciences, vol. 128, no. 2, 1995, pp. 122-33. |
| Adler R, Hurwitz E, Wands JR, Sela M, Shouval D. "Specific targeting of adriamycin conjugates with monoclonal antibodies to hepatoma associated antigens to intrahepatic tumors in athymic mice." Hepatology, vol. 22, no. 5, 1995, pp. 1482-7. |
| Moradpour D, Compagnon B, Wilson BE, Nicolau C, Wands JR. "Specific targeting of human hepatocellular carcinoma cells by immunoliposomes in vitro." Hepatology, vol. 22, no. 5, 1995, pp. 1527-37. |
| Moradpour D, Wands JR. "Understanding hepatitis B virus infection." New England Journal of Medicine, vol. 332, no. 16, 1995, pp. 1092-3. |
| Scaglioni PP, Melegari M, Wands JR. "Characterization of hepatitis B virus core mutants that inhibit viral replication." Virology, vol. 205, no. 1, 1994, pp. 112-20. |
| de la Monte SM, Wands JR. "Diagnostic utility of quantitating neurofilament-immunoreactive Alzheimer's disease lesions." The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, vol. 42, no. 12, 1994, pp. 1625-34. |
| Ackerman Z, Wands JR, Gazitt Y, Brechot C, Kew MC, Shouval D. "Enhancement of HBsAg detection in serum of patients with chronic liver disease following removal of circulating immune complexes." Journal of Hepatology, vol. 20, no. 3, 1994, pp. 398-404. |
| Sasaki Y, Wands JR. "Ethanol impairs insulin receptor substrate-1 mediated signal transduction during rat liver regeneration." Biochemical and Biophysical Research Communications, vol. 199, no. 1, 1994, pp. 403-9. |
| Sasaki Y, Hayashi N, Ito T, Fusamoto H, Kamada T, Wands JR. "Influence of ethanol on insulin receptor substrate-1-mediated signal transduction during rat liver regeneration." Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, vol. 29, no. 1, 1994, pp. 99-106. |
| von Weizsäcker F, Blum HE, Wands JR. "Polymerase chain reaction analysis of hepatitis B virus DNA in formalin-fixed, paraffin-embedded liver biopsies from alcoholics using a simplified and standardized amplification protocol." Journal of Hepatology, vol. 20, no. 5, 1994, pp. 646-9. |
| Liang TJ, Bodenheimer HC Jr, Yankee R, Brown NV, Chang K, Huang J, Wands JR. "Presence of hepatitis B and C viral genomes in US blood donors as detected by polymerase chain reaction amplification." Journal of medical virology, vol. 42, no. 2, 1994, pp. 151-7. |
| Melegari M, Bruno S, Wands JR. "Properties of hepatitis B virus pre-S1 deletion mutants." Virology, vol. 199, no. 2, 1994, pp. 292-300. |
| Wakita T, Wands JR. "Specific inhibition of hepatitis C virus expression by antisense oligodeoxynucleotides. In vitro model for selection of target sequence." Journal of Biological Chemistry, vol. 269, no. 19, 1994, pp. 14205-10. |
| Nishiyama M, Inazawa J, Ariyama T, Nakamura Y, Matsufuji S, Furusaka A, Tanaka T, Hayashi S, Wands JR. "The human insulin receptor substrate-1 gene (IRS1) is localized on 2q36." Genomics, vol. 20, no. 1, 1994, pp. 139-41. |
| Moradpour D, Wands JR. "The molecular pathogenesis of hepatocellular carcinoma." Journal of viral hepatitis, vol. 1, no. 1, 1994, pp. 17-31. |
| Xu YY, Wands JR, de la Monte SM. "Characterization of thread proteins expressed in neuroectodermal tumors." Cancer Research, vol. 53, no. 16, 1993, pp. 3823-9. |
| Moradpour D, Wands JR, Melegari M. "Chasing the escape mutant." Hepatology, vol. 18, no. 4, 1993, pp. 1011-4. |
| Sasaki Y, Zhang XF, Nishiyama M, Avruch J, Wands JR. "Expression and phosphorylation of insulin receptor substrate 1 during rat liver regeneration." Journal of Biological Chemistry, vol. 268, no. 6, 1993, pp. 3805-8. |
| Liang TJ, Makdisi WJ, Sun S, Hasegawa K, Zhang Y, Wands JR, Wu CH, Wu GY. "Targeted transfection and expression of hepatitis B viral DNA in human hepatoma cells." Journal of Clinical Investigation, vol. 91, no. 3, 1993, pp. 1241-6. |
| Bhavani K, Brown NV, Carlson RI, Rhoads D, Wands JR. "The effect of ethanol and extracellular matrix on induction of p36 protein kinase substrate expression in rat hepatocytes." Biochemical and Biophysical Research Communications, vol. 196, no. 3, 1993, pp. 1454-8. |
| Chong JK, Cantrell L, Husain M, Riesing S, Miller BE, Wands J, de la Monte S, Ghanbari HA. "Automated microparticle enzyme immunoassay for neural thread protein in cerebrospinal fluid from Alzheimer's disease patients." Journal of clinical laboratory analysis, vol. 6, no. 6, 1992, pp. 379-83. |
| von Weizsäcker F, Blum HE, Wands JR. "Cleavage of hepatitis B virus RNA by three ribozymes transcribed from a single DNA template." Biochemical and Biophysical Research Communications, vol. 189, no. 2, 1992, pp. 743-8. |
| Nishiyama M, Wands JR. "Cloning and increased expression of an insulin receptor substrate-1-like gene in human hepatocellular carcinoma." Biochemical and Biophysical Research Communications, vol. 183, no. 1, 1992, pp. 280-5. |
| Blum HE, Zhang ZS, Galun E, von Weizsäcker F, Garner B, Liang TJ, Wands JR. "Hepatitis B virus X protein is not central to the viral life cycle in vitro." Journal of Virology, vol. 66, no. 2, 1992, pp. 1223-7. |
| Galun E, Offensperger WB, von Weizsäcker F, Offensperger S, Wands JR, Blum HE. "Human non-hepatocytes support hepadnaviral replication and virion production." The Journal of general virology, vol. 73 ( Pt 1), 1992, pp. 173-8. |
| de la Monte SM, Spratt RA, Chong J, Ghanbari HA, Wands JR. "Immunohistochemical and histopathologic correlates of Alzheimer's disease-associated Alz-50 immunoreactivity quantified in homogenates of cerebral tissue." The American Journal of Pathology, vol. 141, no. 6, 1992, pp. 1459-69. |
| Hurwitz E, Adler R, Shouval D, Takahashi H, Wands JR, Sela M. "Immunotargeting of daunomycin to localized and metastatic human colon adenocarcinoma in athymic mice." Cancer immunology, immunotherapy : CII, vol. 35, no. 3, 1992, pp. 186-92. |
| de la Monte SM, Volicer L, Hauser SL, Wands JR. "Increased levels of neuronal thread protein in cerebrospinal fluid of patients with Alzheimer's disease." Annals of neurology, vol. 32, no. 6, 1992, pp. 733-42. |
| Wands JR, Liang TJ, Blum HE, Shafritz DA. "Molecular pathogenesis of liver disease during persistent hepatitis B virus infection." Seminars in liver disease, vol. 12, no. 3, 1992, pp. 252-64. |
| de la Monte SM, Wands JR. "Neuronal thread protein over-expression in brains with Alzheimer's disease lesions." Journal of the Neurological Sciences, vol. 113, no. 2, 1992, pp. 152-64. |
| Galvin K, Krishna S, Ponchel F, Frohlich M, Cummings DE, Carlson R, Wands JR, Isselbacher KJ, Pillai S, Ozturk M. "The major histocompatibility complex class I antigen-binding protein p88 is the product of the calnexin gene." Proceedings of the National Academy of Sciences, vol. 89, no. 18, 1992, pp. 8452-6. |
| Liang TJ, Hasegawa K, Rimon N, Wands JR, Ben-Porath E. "A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis." New England Journal of Medicine, vol. 324, no. 24, 1991, pp. 1705-9. |
| Hasegawa K, Huang JK, Wands JR, Obata H, Liang TJ. "Association of hepatitis B viral precore mutations with fulminant hepatitis B in Japan." Virology, vol. 185, no. 1, 1991, pp. 460-3. |
| Wands JR, Blum HE. "Hepatitis B and C virus and alcohol-induced liver injury." Hepatology, vol. 14, no. 4 Pt 1, 1991, pp. 730-3. |
| Liang TJ, Baruch Y, Ben-Porath E, Enat R, Bassan L, Brown NV, Rimon N, Blum HE, Wands JR. "Hepatitis B virus infection in patients with idiopathic liver disease." Hepatology, vol. 13, no. 6, 1991, pp. 1044-51. |
| Blum HE, Galun E, von Weizsäcker F, Wands JR. "Inhibition of hepatitis B virus by antisense oligodeoxynucleotides." The Lancet, vol. 337, no. 8751, 1991, pp. 1230. |
| Blum HE, Galun E, Liang TJ, von Weizsäcker F, Wands JR. "Naturally occurring missense mutation in the polymerase gene terminating hepatitis B virus replication." Journal of Virology, vol. 65, no. 4, 1991, pp. 1836-42. |
| Blum HE, Liang TJ, Galun E, Wands JR. "Persistence of hepatitis B viral DNA after serological recovery from hepatitis B virus infection." Hepatology, vol. 14, no. 1, 1991, pp. 56-63. |
| Wands JR, Blum HE. "Primary hepatocellular carcinoma." New England Journal of Medicine, vol. 325, no. 10, 1991, pp. 729-31. |
| Takahashi H, Wands JR. "Prognosis of hepatocellular carcinoma: known to be poor: yet difficult to predict." Journal of Nuclear Medicine, vol. 32, no. 2, 1991, pp. 235-6. |
| Bressac B, Kew M, Wands J, Ozturk M. "Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa." J. Geophys. Res., vol. 350, no. 6317, 1991, pp. 429-31. |
| Wilson BE, Sun S, Ozturk M, Wands JR. "Stability of monoclonal antibody-defined epitopes." Journal of immunological methods, vol. 139, no. 1, 1991, pp. 55-64. |
| Hurwitz E, Stancovski I, Wilchek M, Shouval D, Takahashi H, Wands JR, Sela M. "A conjugate of 5-fluorouridine-poly(L-lysine) and an antibody reactive with human colon carcinoma." Bioconjugate Chem., vol. 1, no. 4, 1990, pp. 285-90. |
| Ozturk M, Milunsky A, Brambati B, Sachs ES, Miller SL, Wands JR. "Abnormal maternal serum levels of human chorionic gonadotropin free subunits in trisomy 18." American journal of medical genetics, vol. 36, no. 4, 1990, pp. 480-3. |
| Bressac B, Galvin KM, Liang TJ, Isselbacher KJ, Wands JR, Ozturk M. "Abnormal structure and expression of p53 gene in human hepatocellular carcinoma." Proceedings of the National Academy of Sciences, vol. 87, no. 5, 1990, pp. 1973-7. |
| Liang TJ, Blum HE, Wands JR. "Characterization and biological properties of a hepatitis B virus isolated from a patient without hepatitis B virus serologic markers." Hepatology, vol. 12, no. 2, 1990, pp. 204-12. |
| de la Monte SM, Ozturk M, Wands JR. "Enhanced expression of an exocrine pancreatic protein in Alzheimer's disease and the developing human brain." Journal of Clinical Investigation, vol. 86, no. 3, 1990, pp. 1004-13. |
| Frohlich M, Motté P, Galvin K, Takahashi H, Wands J, Ozturk M. "Enhanced expression of the protein kinase substrate p36 in human hepatocellular carcinoma." Molecular and Cellular Biology, vol. 10, no. 6, 1990, pp. 3216-23. |
| Nishiyama M, Ozturk M, Frohlich M, Mafune K, Steele G Jr, Wands JR. "Expression of human alpha-actinin in human hepatocellular carcinoma." Cancer Research, vol. 50, no. 19, 1990, pp. 6291-4. |
| Nebiolo L, Ozturk M, Brambati B, Miller S, Wands J, Milunsky A. "First-trimester maternal serum alpha-fetoprotein and human chorionic gonadotropin screening for chromosome defects." Prenat Diagn, vol. 10, no. 9, 1990, pp. 575-81. |
| Paterlini P, Gerken G, Nakajima E, Terre S, D'Errico A, Grigioni W, Nalpas B, Franco D, Wands J, Kew M. "Polymerase chain reaction to detect hepatitis B virus DNA and RNA sequences in primary liver cancers from patients negative for hepatitis B surface antigen." New England Journal of Medicine, vol. 323, no. 2, 1990, pp. 80-5. |
| Motté P, Takahashi H, Ozturk M, Wilson BE, Wands JR. "Characterization of a malignant phenotype-associated cell surface glycoprotein common to various human tumor cells and preferentially expressed on adenocarcinoma of the lung." Cancer Research, vol. 49, no. 6, 1989, pp. 1349-56. |
| Ozturk M, de la Monte SM, Gross J, Wands JR. "Elevated levels of an exocrine pancreatic secretory protein in Alzheimer disease brain." Proceedings of the National Academy of Sciences, vol. 86, no. 2, 1989, pp. 419-23. |
| Berkowitz R, Ozturk M, Goldstein D, Bernstein M, Hill L, Wands JR. "Human chorionic gonadotropin and free subunits' serum levels in patients with partial and complete hydatidiform moles." Obstetrics and gynecology, vol. 74, no. 2, 1989, pp. 212-6. |
| Ozturk M, Motté P, Takahashi H, Frohlich M, Wilson B, Hill L, Bressac B, Wands JR. "Identification and characterization of a Mr 50,000 adrenal protein in human hepatocellular carcinoma." Cancer Research, vol. 49, no. 23, 1989, pp. 6764-73. |
| Takahashi H, Ozturk M, Wilson B, Maki A, Ozawa K, Koizumi M, Endo K, Strauss W, Shouval D, Wands J. "In vivo expression of two novel tumor-associated antigens and their use in immunolocalization of human hepatocellular carcinoma." Hepatology, vol. 9, no. 4, 1989, pp. 625-34. |
| Takahashi H, Carlson R, Ozturk M, Sun S, Motte P, Strauss W, Isselbacher KJ, Wands JR, Shouval D. "Radioimmunolocation of hepatic and pulmonary metastasis of human colon adenocarcinoma." Gastroenterology, vol. 96, no. 5 Pt 1, 1989, pp. 1317-29. |
| Liang TJ, Isselbacher KJ, Wands JR. "Rapid identification of low level hepatitis B-related viral genome in serum." Journal of Clinical Investigation, vol. 84, no. 4, 1989, pp. 1367-71. |
| Wilson B, Ozturk M, Takahashi H, Motté P, Kew M, Isselbacher KJ, Wands JR. "Cell-surface changes associated with transformation of human hepatocytes to the malignant phenotype." Proceedings of the National Academy of Sciences, vol. 85, no. 9, 1988, pp. 3140-4. |
| Takahashi H, Kameda H, Wands JR. "Development of a second generation monoclonal immunoradiometric assay. Increased sensitivity leads to enhanced detection of hepatitis B viral infection." Journal of immunological methods, vol. 112, no. 2, 1988, pp. 191-200. |
| Ozturk M, Berkowitz R, Goldstein D, Bellet D, Wands JR. "Differential production of human chorionic gonadotropin and free subunits in gestational trophoblastic disease." American Journal of Obstetrics and Gynecology, vol. 158, no. 1, 1988, pp. 193-8. |
| Shouval D, Adler R, Wands JR, Hurwitz E, Isselbacher KJ, Sela M. "Doxorubicin conjugates of monoclonal antibodies to hepatoma-associated antigens." Proceedings of the National Academy of Sciences, vol. 85, no. 21, 1988, pp. 8276-80. |
| Carter EA, Wands JR. "Ethanol-induced inhibition of liver cell function: I. Effect of ethanol on hormone stimulated hepatocyte DNA synthesis and the role of ethanol metabolism." Alcoholism: Clinical and Experimental Research, vol. 12, no. 4, 1988, pp. 555-62. |
| Milunsky A, Wands J, Brambati B, Bonacchi I, Currie K. "First-trimester maternal serum alpha-fetoprotein screening for chromosome defects." American Journal of Obstetrics and Gynecology, vol. 159, no. 5, 1988, pp. 1209-13. |
| Takahashi H, Wilson B, Ozturk M, Motté P, Strauss W, Isselbacher KJ, Wands JR. "In vivo localization of human colon adenocarcinoma by monoclonal antibody binding to a highly expressed cell surface antigen." Cancer Research, vol. 48, no. 22, 1988, pp. 6573-9. |
| Ozturk M, Brown N, Milunsky A, Wands J. "Physiological studies of human chorionic gonadotropin and free subunits in the amniotic fluid compartment compared to those in maternal serum." The Journal of Clinical Endocrinology & Metabolism, vol. 67, no. 6, 1988, pp. 1117-21. |
| Thiers V, Nakajima E, Kremsdorf D, Mack D, Schellekens H, Driss F, Goudeau A, Wands J, Sninsky J, Tiollais P. "Transmission of hepatitis B from hepatitis-B-seronegative subjects." The Lancet, vol. 2, no. 8623, 1988, pp. 1273-6. |
| Ozturk M, Bellet D, Isselbacher KJ, Wands J. "Ectopic beta-human chorionic gonadotropin production by a human hepatoma cell line (FOCUS): isolation and immunochemical characterization." Endocrinology, vol. 120, no. 2, 1987, pp. 559-66. |
| Pol S, Thiers V, Nalpas B, Degos F, Gazengel C, Carnot F, Tiollais P, Wands JR, Berthelot P, Brechot C. "Monoclonal anti-HBs antibodies radioimmunoassay and serum HBV-DNA hybridization as diagnostic tools of HBV infection: relative prevalence among HBsAg-negative alcoholics, patients with chronic hepatitis or hepatocellular carcinomas and blood donors." European journal of clinical investigation, vol. 17, no. 6, 1987, pp. 515-21. |
| Ozturk M, Bellet D, Manil L, Hennen G, Frydman R, Wands J. "Physiological studies of human chorionic gonadotropin (hCG), alpha hCG, and beta hCG as measured by specific monoclonal immunoradiometric assays." Endocrinology, vol. 120, no. 2, 1987, pp. 549-58. |
| Wilson B, Wands J. "Recent advances in the biology and immunology of hepatitis B." Bailliere's clinical gastroenterology, vol. 1, no. 3, 1987, pp. 623-45. |
| Bellet DH, Bidart JM, Ozturk M, Troalen F, Ghillani P, Pernas P, Wands JR, Bohuon CJ. "Synthetic peptides and monoclonal antibodies of predetermined specificity in the study of human chorionic gonadotropin." International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, vol. 14, no. 4, 1987, pp. 295-304. |
| Shih C, Burke K, Chou MJ, Zeldis JB, Yang CS, Lee CS, Isselbacher KJ, Wands JR, Goodman HM. "Tight clustering of human hepatitis B virus integration sites in hepatomas near a triple-stranded region." Journal of Virology, vol. 61, no. 11, 1987, pp. 3491-8. |
| Kew MC, Fujita Y, Takahashi H, Coppins A, Wands JR. "Comparison between polyclonal and first and second generation monoclonal radioimmunoassays in the detection of hepatitis B surface antigen in patients with hepatocellular carcinoma." Hepatology, vol. 6, no. 4, 1986, pp. 636-9. |
| Shouval D, Adler R, Wands JR, Hurwitz E. "Conjugates between monoclonal antibodies to HBsAg and cytosine arabinoside." Journal of Hepatology, vol. 3 Suppl 2, 1986, pp. S87-95. |
| Zeldis JB, Ben-Porath E, Enat R, Kirsch K, Wands J. "Correlation of HBV DNA and monoclonal reactivity to HBsAg in serum of patients with HBV infection." Journal of virological methods, vol. 14, no. 2, 1986, pp. 153-66. |
| Fujita YK, Kamata K, Kameda H, Isselbacher KJ, Wands JR. "Detection of hepatitis B virus infection in hepatitis B surface antigen-negative hemodialysis patients by monoclonal radioimmunoassays." Gastroenterology, vol. 91, no. 6, 1986, pp. 1357-63. |
| Monath TP, Wands JR, Hill LJ, Brown NV, Marciniak RA, Wong MA, Gentry MK, Burke DS, Grant JA, Trent DW. "Geographic classification of dengue-2 virus strains by antigen signature analysis." Virology, vol. 154, no. 2, 1986, pp. 313-24. |
| Ben-Porath E, Fujita YK, Wands JR. "Hepatitis B monoclonal antibody testing." Progress in liver diseases, vol. 8, 1986, pp. 347-66. |
| Wands JR, Fujita YK, Isselbacher KJ, Degott C, Schellekens H, Dazza MC, Thiers V, Tiollais P, Brechot C. "Identification and transmission of hepatitis B virus-related variants." Proceedings of the National Academy of Sciences, vol. 83, no. 17, 1986, pp. 6608-12. |
| Monath TP, Wands JR, Hill LJ, Gentry MK, Gubler DJ. "Multisite monoclonal immunoassay for dengue viruses: detection of viraemic human sera and interference by heterologous antibody." The Journal of general virology, vol. 67 ( Pt 4), 1986, pp. 639-50. |
| Ratner AV, Carter EA, Pohost GM, Wands JR. "Nuclear magnetic resonance spectroscopy and imaging in the study of experimental liver diseases." Alcoholism: Clinical and Experimental Research, vol. 10, no. 3, 1986, pp. 241-5. |
| Bellet DH, Ozturk M, Bidart JM, Bohuon CJ, Wands JR. "Sensitive and specific assay for human chorionic gonadotropin (hCG) based on anti-peptide and anti-hCG monoclonal antibodies: construction and clinical implications." The Journal of Clinical Endocrinology & Metabolism, vol. 63, no. 6, 1986, pp. 1319-27. |
| Monath TP, Hill LJ, Brown NV, Cropp CB, Schlesinger JJ, Saluzzo JF, Wands JR. "Sensitive and specific monoclonal immunoassay for detecting yellow fever virus in laboratory and clinical specimens." Journal of clinical microbiology, vol. 23, no. 1, 1986, pp. 129-34. |
| Carlson RI, Ben-Porath E, Shouval D, Strauss W, Isselbacher KJ, Wands JR. "Antigenic characterization of human hepatocellular carcinoma. Development of in vitro and in vivo immunoassays that use monoclonal antibodies." Journal of Clinical Investigation, vol. 76, no. 1, 1985, pp. 40-51. |
| Gazitt Y, Margel S, Lerner A, Wands JR, Shouval D. "Development of a novel C1q immunoadsorbent for removal of circulating immunecomplexes: quantitative isolation of hepatitis B virus surface antigen and immunecomplexes." Immunology letters, vol. 11, no. 1, 1985, pp. 1-8. |
| Carter EA, Wands JR. "Ethanol inhibits hormone stimulated hepatocyte DNA synthesis." Biochemical and Biophysical Research Communications, vol. 128, no. 2, 1985, pp. 767-74. |
| Bréchot C, Degos F, Lugassy C, Thiers V, Zafrani S, Franco D, Bismuth H, Trépo C, Benhamou JP, Wands J. "Hepatitis B virus DNA in patients with chronic liver disease and negative tests for hepatitis B surface antigen." New England Journal of Medicine, vol. 312, no. 5, 1985, pp. 270-6. |
| Shouval D, Eilat D, Carlson RI, Adler R, Livni N, Wands JR. "Human hepatoma-associated cell surface antigen: identification and characterization by means of monoclonal antibodies." Hepatology, vol. 5, no. 3, 1985, pp. 347-56. |
| Bidart JM, Ozturk M, Bellet DH, Jolivet M, Gras-Masse H, Troalen F, Bohuon CJ, Wands JR. "Identification of epitopes associated with hCG and the beta hCG carboxyl terminus by monoclonal antibodies produced against a synthetic peptide." The Journal of Immunology, vol. 134, no. 1, 1985, pp. 457-64. |
| Ben-Porath E, Wands JR, Bar-Shany S, Huggins C, Isselbacher K. "Improved detection of hepatitis B surface antigen (HBsAg) in blood donors by monoclonal radioimmunoassay." Transfusion, vol. 25, no. 1, 1985, pp. 10-4. |
| Gross J, Carlson RI, Brauer AW, Margolies MN, Warshaw AL, Wands JR. "Isolation, characterization, and distribution of an unusual pancreatic human secretory protein." Journal of Clinical Investigation, vol. 76, no. 6, 1985, pp. 2115-26. |
| Wands JR, Isselbacher KJ, Brechot C, Tiollais P. "Monoclonal radioimmunoassays and HBV-DNA hybridisation in hepatocellular carcinoma." The Lancet, vol. 1, no. 8426, 1985, pp. 455. |
| Ben-Porath E, Wands JR, Marciniak RA, Wong MA, Hornstein L, Ryder R, Canlas M, Lingao A, Isselbacher KJ. "Structural analysis of hepatitis B surface antigen by monoclonal antibodies." Journal of Clinical Investigation, vol. 76, no. 4, 1985, pp. 1338-47. |
| Ben-Porath E, Wands J, Gruia M, Isselbacher K. "Clinical significance of enhanced detection of HBsAg by a monoclonal radioimmunoassay." Hepatology, vol. 4, no. 5, 1984, pp. 803-7. |
| Cooper DS, Carter EA, Kieffer JD, Wands JR. "Effects of propylthiouracil on D-galactosamine hepatotoxicity in the rat. Evidence for a non-thyroidal effect." Biochemical pharmacology, vol. 33, no. 21, 1984, pp. 3391-7. |
| He L, Isselbacher KJ, Wands JR, Goodman HM, Shih C, Quaroni A. "Establishment and characterization of a new human hepatocellular carcinoma cell line." In vitro, vol. 20, no. 6, 1984, pp. 493-504. |
| Wands JR, Wong MA, Shorey J, Brown RD, Marciniak RA, Isselbacher KJ. "Hepatitis B viral antigenic structure: signature analysis by monoclonal radioimmunoassays." Proceedings of the National Academy of Sciences, vol. 81, no. 7, 1984, pp. 2237-41. |
| Ben-Porath E, Wands JR. "Monoclonal antibodies as diagnostic probes in the etiology of hepatitis." Seminars in liver disease, vol. 4, no. 1, 1984, pp. 76-88. |
| Bellet DH, Wands JR, Isselbacher KJ, Bohuon C. "Serum alpha-fetoprotein levels in human disease: perspective from a highly specific monoclonal radioimmunoassay." Proceedings of the National Academy of Sciences, vol. 81, no. 12, 1984, pp. 3869-73. |
| Wands JR. "Non-A, non-B hepatitis." Hepatology, vol. 3, no. 5, 1983, pp. 764-6. |
| Marciniak RA, Wands JR, Bruns RR, Malchesky PS, Nose Y, Haber E. "Quantitative removal of hepatitis B viral antigens from serum by a monoclonal IgM coupled to a biocompatible solid-phase support." Proceedings of the National Academy of Sciences, vol. 80, no. 12, 1983, pp. 3821-5. |
| Bhan AK, Dienstag JL, Wands JR, Schlossman SF, Reinherz EL. "Alterations of T-cell subsets in primary biliary cirrhosis." Clinical and experimental immunology, vol. 47, no. 2, 1982, pp. 351-8. |
| Wands JR, Marciniak RA, Isselbacher KJ, Varghese M, Don G, Halliday JW, Powell LW. "Demonstration of previously undetected hepatitis B viral determinants in an Australian Aboriginal population by monoclonal anti-hbs antibody radioimmunoassays." The Lancet, vol. 1, no. 8279, 1982, pp. 977-80. |
| Wands JR, Lieberman HM, Muchmore E, Isselbacher K, Shafritz DA. "Detection and transmission in chimpanzees of hepatitis B virus-related agents formerly designated "non-A, non-B" hepatitis." Proceedings of the National Academy of Sciences, vol. 79, no. 23, 1982, pp. 7552-6. |
| Hodgson HJ, Wands JR, Isselbacher KJ. "Experimental murine hepatitis and inducible suppressor cell function." Journal of clinical & laboratory immunology, vol. 7, no. 1, 1982, pp. 45-9. |
| Shouval D, Shafritz DA, Zurawski VR Jr, Isselbacher KJ, Wands JR. "Immunotherapy in nude mice of human hepatoma using monoclonal antibodies against hepatitis B virus." J. Geophys. Res., vol. 298, no. 5874, 1982, pp. 567-9. |
| Wands JR, Bruns RR, Carlson RI, Ware A, Menitove JE, Isselbacher KJ. "Monoclonal IgM radioimmunoassay for hepatitis B surface antigen: high binding activity in serum that is unreactive with conventional antibodies." Proceedings of the National Academy of Sciences, vol. 79, no. 4, 1982, pp. 1277-81. |
| Shafritz DA, Lieberman HM, Isselbacher KJ, Wands JR. "Monoclonal radioimmunoassays for hepatitis B surface antigen: demonstration of hepatitis B virus DNA or related sequences in serum and viral epitopes in immune complexes." Proceedings of the National Academy of Sciences, vol. 79, no. 18, 1982, pp. 5675-9. |
| Shouval D, Wands JR, Zurawski VR Jr, Isselbacher KJ, Shafritz DA. "Selecting binding and complement-mediated lysis of human hepatoma cells (PLC/PRF/5) in culture by monoclonal antibodies to hepatitis B surface antigen." Proceedings of the National Academy of Sciences, vol. 79, no. 2, 1982, pp. 650-4. |
| Goodson JD, Taylor PA, Campion EW, Richter JM, Wands J. "The clinical course of acute hepatitis in the elderly patient." Arch Intern Med, vol. 142, no. 8, 1982, pp. 1485-8. |
| Dienstag JL, Weake JR, Wands JR. "Abnormalities of mononuclear cell regulation in vitro in primary biliary cirrhosis." Liver, vol. 1, no. 3, 1981, pp. 230-43. |
| Popp JW Jr, Harrist TJ, Dienstag JL, Bhan AK, Wands JR, LaMont JT, Mihm MC Jr. "Cutaneous vasculitis associated with acute and chronic hepatitis." Arch Intern Med, vol. 141, no. 5, 1981, pp. 623-9. |
| Wands JR, Zurawski VR Jr. "High affinity monoclonal antibodies to hepatitis B surface antigen (HBsAg) produced by somatic cell hybrids." Gastroenterology, vol. 80, no. 2, 1981, pp. 225-32. |
| Wands JR, Carlson RI, Schoemaker H, Isselbacher KJ, Zurawski VR Jr. "Immunodiagnosis of hepatitis B with high-affinity IgM monoclonal antibodies." Proceedings of the National Academy of Sciences, vol. 78, no. 2, 1981, pp. 1214-8. |
| Wands JR, Dienstag JL, Weake JR, Koff RS. "In vitro studies of enhanced IgG synthesis in severe alcoholic liver disease." Clinical and experimental immunology, vol. 44, no. 2, 1981, pp. 396-404. |
| Wands JR, Carter EA, Bucher NL, Isselbacher KJ. "Effect of acute and chronic ethanol intoxication on hepatic regeneration." Systems Biology of RNA Binding Proteins, vol. 132, 1980, pp. 663-70. |
| Popp JW Jr, Dienstag JL, Wands JR, Bloch KJ. "Essential mixed cryoglobulinemia without evidence for hepatitis B virus infection." Annals of Internal Medicine, vol. 92, no. 3, 1980, pp. 379-83. |
| Klingenstein RJ, Wands JR. "Immunologic effector mechanisms in hepatitis B-negative chronic active hepatitis." Springer seminars in immunopathology, vol. 3, no. 3, 1980, pp. 317-29. |
| Quaroni A, Wands J, Trelstad RL, Isselbacher KJ. "Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria." The Journal of cell biology, vol. 80, no. 2, 1979, pp. 248-65. |
| Wands JR, Carter EA, Bucher NL, Isselbacher KJ. "Inhibition of hepatic regeneration in rats by acute and chronic ethanol intoxication." Gastroenterology, vol. 77, no. 3, 1979, pp. 528-31. |
| Wands JR. "Viral hepatitis and its effect on pregnancy." Clinical obstetrics and gynecology, vol. 22, no. 2, 1979, pp. 301-11. |
| Hodgson HJ, Wands JR, Isselbacher KJ. "Alteration in suppressor cell activity in chronic active hepatitis." Proceedings of the National Academy of Sciences, vol. 75, no. 3, 1978, pp. 1549-53. |
| Wands JR, Dienstag JL, Bhan AK, Feller ER, Isselbacher KJ. "Circulating immune complexes and complement activation in primary biliary cirrhosis." New England Journal of Medicine, vol. 298, no. 5, 1978, pp. 233-7. |
| Hodgson HJ, Wands JR, Isselbacher KJ. "Decreased suppressor cell activity in inflammatory bowel disease." Clinical and experimental immunology, vol. 32, no. 3, 1978, pp. 451-8. |
| Wands JR, Dienstag JL. "Inhibition of lymphocyte cytotoxicity by serum from patients with alcoholic liver disease: partial characterization of serum inhibitors." The Yale journal of biology and medicine, vol. 51, no. 6, 1978, pp. 615-23. |
| Dienstag JL, Carter EA, Wands JR, Isselbacher KJ, Fischer JE. "Plasma alpha-amino-n-butyric acid to leucine ratio: nonspecificity as a marker for alcoholism." Gastroenterology, vol. 75, no. 4, 1978, pp. 561-5. |
| Dienstag JL, Rhodes AR, Bhan AK, Dvorak AM, Mihm MC Jr, Wands JR. "Urticaria associated with acute viral hepatitis type B: studies of pathogenesis." Annals of Internal Medicine, vol. 89, no. 1, 1978, pp. 34-40. |
| Carter EA, Wands JR, Isselbacher KJ. "Effect of acute murine hepatitis (MHV-1-59) on ethanol oxidation in vivo." Gastroenterology, vol. 73, no. 2, 1977, pp. 321-6. |
| Feller ER, Pont A, Wands JR, Carter EA, Foster G, Kourides IA, Isselbacher KJ. "Familial hemochromatosis. Physiologic studies in the precirrhotic stage of the disease." New England Journal of Medicine, vol. 296, no. 25, 1977, pp. 1422-6. |
| Rowe JW, Wands JR, Mezey E, Waterbury LA, Wright JR, Tobin J, Andres R. "Familial hemochromatosis: characteristics of the precirrhotic stage in a large kindred." Medicine, vol. 56, no. 3, 1977, pp. 197-211. |
| Dienstag JL, Wands JR, Isselbacher KJ. "Hepatitis B and essential mixed cryoglobulinemia." New England Journal of Medicine, vol. 297, no. 17, 1977, pp. 946-7. |
| Carter ES, Wands JR, Alpert E, Isselbacher KJ. "Measurement and specificity of serum dna polymerase." New England Journal of Medicine, vol. 296, no. 3, 1977, pp. 173-4. |
| Wands JR, LaMont JT, Mann E, Isselbacher KJ. "Arthritis associated with intestinal-bypass procedure for morbid obesity. Complement activation and characterization of circulating cryoproteins." New England Journal of Medicine, vol. 294, no. 3, 1976, pp. 121-4. |
| Farivar M, Wands JR, Isselbacher KJ, Bucher NL. "Beneficial effect of insulin and glucagon in fulminant murine viral hepatitis." The Lancet, vol. 1, no. 7961, 1976, pp. 696-7. |
| Wands JR, Perrotto JL, Isselbacher KJ. "Circulating immune complexes and complement sequence activation in infectious mononucleosis." The American Journal of Medicine, vol. 60, no. 2, 1976, pp. 269-72. |
| Farivar M, Wands JR, Benson GD, Dienstag JL, Isselbacher KJ. "Cryoprotein complexes and peripheral neuropathy in a patient with chronic active hepatitis." Gastroenterology, vol. 71, no. 3, 1976, pp. 490-3. |
| Farivar M, Wands JR, Isselbacher KJ, Bucher NL. "Effect of insulin and glucagon on fulminant murine hepatitis." New England Journal of Medicine, vol. 295, no. 27, 1976, pp. 1517-9. |
| Elfenbein GJ, Anderson PN, Humphrey RL, Mullins GM, Sensenbrenner LL, Wands JR, Santos GW. "Immune system reconstitution following allogeneic bone marrow transplantation in man: a multiparameter analysis." Transplantation Proceedings, vol. 8, no. 4, 1976, pp. 641-6. |
| Wands JR, Podolsky DK, Isselbacher KJ. "Mechanism of human lymphocyte stimulation by concanavalin A: role of valence and surface binding sites." Proceedings of the National Academy of Sciences, vol. 73, no. 6, 1976, pp. 2118-22. |
| Wands JR, Rowe JA, Mezey SE, Waterbury LA, Wright JR, Halliday JW, Isselbacher KJ, Powell LW. "Normal serum ferritin concentrations in precirrhotic hemochromatosis." New England Journal of Medicine, vol. 294, no. 6, 1976, pp. 302-5. |
| Wands JR, Alpert E, Isselbacher KJ. "Arthritis associated with chronic active hepatitis: complement activation and characterization of circulating immune complexes." Gastroenterology, vol. 69, no. 6, 1975, pp. 1286-91. |
| Wands JR, Perrotto JL, Alpert E, Isselbacher KJ. "Cell-mediated immunity in acute and chronic hepatitis." Journal of Clinical Investigation, vol. 55, no. 5, 1975, pp. 921-9. |
| Wands JR. "Letter: Subacute and chronic active hepatitis after withdrawal of chemotherapy." The Lancet, vol. 2, no. 7942, 1975, pp. 979. |
| Wands JR, Chura CM, Roll FJ, Maddrey WC. "Serial studies of hepatitis-associated antigen and antibody in patients receiving antitumor chemotherapy for myeloproliferative and lymphoproliferative disorders." Gastroenterology, vol. 68, no. 1, 1975, pp. 105-12. |
| Wands JR, Mann E, Alpert E, Isselbacher KJ. "The pathogenesis of arthritis associated with acute hepatitis-B surface antigen-positive hepatitis. Complement activation and characterization of circulating immune complexes." Journal of Clinical Investigation, vol. 55, no. 5, 1975, pp. 930-6. |
| Davis LE, Wands JR, Weiss SA, Price DL, Girling EF. "Central nervous system intoxication from mercurous chloride laxatives. Quantitative, histochemical, and ultrastructural studies." Archives of Neurology, vol. 30, no. 6, 1974, pp. 428-31. |
| Wands JR, Weiss SW, Yardley JH, Maddrey WC. "Chronic inorganic mercury poisoning due to laxative abuse. A clinical and ultrastructural study." The American Journal of Medicine, vol. 57, no. 1, 1974, pp. 92-101. |
| Wands JR, Walker JA, Davis TT, Waterbury LA, Owens AH, Carpenter CC. "Hepatitis B in an oncology unit." New England Journal of Medicine, vol. 291, no. 26, 1974, pp. 1371-5. |
| Levin ML, Maddrey WC, Wands JR, Mendeloff AL. "Hepatitis B transmission by dentists." JAMA, vol. 228, no. 9, 1974, pp. 1139-40. |
| Mitch WE, Wands JR, Maddrey WC. "Hepatitis B transmission in a family." JAMA, vol. 227, no. 9, 1974, pp. 1043-4. |
| James S, Outten W, Davis PJ, Wands J. "House staff scheduling: a computer-aided method." Annals of Internal Medicine, vol. 80, no. 1, 1974, pp. 70-3. |
| Burton JR, Wands JR, Voigt GC, Sterioff S Jr, Caralis DG, Zachary JB, Smith GW. "An approach to pericardial effusion in hemodialysis patients." The Johns Hopkins medical journal, vol. 133, no. 6, 1973, pp. 312-20. |
| Wands JR, Mann RB, Jackson D, Butler T. "Fatal community-acquired Herellea pneumonia in chronic renal disease. Case report." The American review of respiratory disease, vol. 108, no. 4, 1973, pp. 964-7. |
| Wands JR, Salyer DC, Boitnott JK, Maddrey WC. "Fulminant hepatitis complicated by pancreatitis." The Johns Hopkins medical journal, vol. 133, no. 3, 1973, pp. 156-60. |
| Fisch HP, Wands J, Yeung J, Davis PJ. "Pulmonary edema and disseminated intravascular coagulation after intravenous abuse of d-propoxyphene (darvon)." Southern Medical Journal, vol. 65, no. 4, 1972, pp. 493-5. |
| Wands JR, Smuckler EA, Woodbury WJ. "Transmembrane potential changes in liver cells following CCl4 intoxication." The American Journal of Pathology, vol. 58, no. 3, 1970, pp. 499-508. |
1. National Institutes of Health Grants
2. Sponsored Research Agreements
3. Foundation Grants
4. Institutional Funds
REVIEWS, CHAPTERS, EDITORIALS
1. Wands JR, Alpert E. Immunology of viral hepatitis. In: Mathiew A, Kahn B (eds). Immunological Aspects of Anesthesia and Surgical Practice. New York:Grun & Stratton,1977:191- 203.
2. Wands JR, Koff RS, Isselbacher KJ. Acute hepatitis. In: Thorn G et al. (eds). Harrison’s Principles of Internal Medicine, 8th Edition. New York:McGraw-Hill, Inc. 1977:1600-4.
3. Wands JR, Koff RS, Isselbacher KJ. Chronic active hepatitis. In: Thorn G et al. (eds). Harrison’s Principles of Internal Medicine, 8th Edition. New York:McGraw-Hill, Inc. 1977;1600-4.
4. Popp JW, Wands JR. Recent views on the recognition of hemochromatosis. In: Davidson CS (ed). Problems in Liver Disease. New York:Stratton Intercontinental Medical Book Corp. 1979:301-11.
5. Wands JR. Viral hepatitis and its effect on pregnancy. In: Jewett JF, Kitzmiller JL, Schoenbaum SC (eds). Clinical Obstetrics and Gynecology. Maryland:Harper & Row 1979:309-20.
6. Wands JR. Alcohol and the immune response. In: Majchrowicz E, Noble EP (eds). Pharmacology of Ethanol, Vol. 7. New York:Plenum Press 1979:363-73.
7. Wands JR, Carter EA, Bucher NLR, Isselbacher KJ. Effect of acute and chronic ethanol intoxication of hepatic regeneration. In: Thurman RG et al (eds). Advances in Experimental Medicine and Biology 1980;132:663-70.
8. Klingenstein FJ, Wands JR. Immunologic effector mechanisms in hepatitis B-negative chronic hepatitis. In: Thomas H, Miescher PA (eds). Seminars in Immunopathology 1980;3:317-29.
9. Wands JR. Viral hepatitis in the compromised host. In: Rubin HR, Young LS (eds). Clinical Approach to Infection in the Immuno-Compromised Host. New York:Plenum Press 1981.
10. Zurawski VR, Delvillano BC, Wands JR. Monoclonal antibodies to hepatitis B surface antigen. In: Hammering et al (eds). Monoclonal Antibodies and T-Cell Hybridomas. New York:Elsevier 1981;273-82.
11. Klingenstein RJ, Wands JR. The development of animal models in chronic active hepatitis. In: Cohen S, Soloway RD (eds). Contemporary Issues in Gastroenterology. New York:Churchill Livingston 1983:249-59.
12. Wands JR. CPC – Primary Biliary Cirrhosis. N Engl J Med 1982;307:44-50.
13. Friedman L, Wands JR. Cirrhosis. In: Conn HF (ed). Current Therapy. Philadelphia:WB Saunders Co. 1983;356-61.
14. Friedman L, Wands JR. Non-A, non-B hepatitis. In: Isselbacher KJ et al (eds). Harrison’s Principles of Internal Medicine. New York:McGraw-Hill 1984;97-115.
15. Wands JR, Ben-Porath E, Wong MA. Use of monoclonal antibodies in the study of viral hepatitis. In: Chisari F (ed). Advances in Hepatitis Research. New York:Mason Publ. Co. 1984;110-22.
16. Wands JR: Non-A, non-B hepatitis (editorial). Hepatology 1984;3:542-7.
17. Ben-Porath E, Wands JR. Monoclonal antibodies as diagnostic probes in the etiology of hepatitis. Seminars Liver Disease 1984;4:76-88.
18. Wands JR, Ben-Porath E, Wong Am. Monoclonal antibodies and hepatitis B: A new perspective using highly sensitive and specific radioimmunoassay. In: Vyas GN, Dienstag JL, Hoofnagle JH (eds). Viral Hepatitis and Liver Disease. NY:Grune & Stratton 1984;543-59.
19. Bellet DH, Ozturk M, Wands JR, Bidart JM, Assicot M, Troalen F, Bohoun C. Monoclonal antibodies directed toward unique epitopes on human chorionic gonadotropin: an approach to the development of sensitive and specific radioimmunoassays. In: Bizollon CA (ed). Monoclonal Antibodies and New Trends in Immunoassays. Amsterdam:Elsevier 1984;43-52.
20. Shouval D, Wands JR, Shafritz DA. Immunotherapy of human hepatocellular carcinoma: molecular and cellular studies with monoclonal antibodies to hepatitis B viral determinants. In: Hadwick CM (Ed). Receptors in Tumor Biology. New York:Marcel Dekker Inc. 1986.
21. Ben-Porath E, Fujita YK, Wands JR. Hepatitis B monoclonal antibody testing. In: Popper H, Shaffner F (eds). Progress in Liver Diseases, Vol. VIII. NY:Grune & Stratton 1986.
22. Smith A, Wands JR. Hepatic failure. In: Parrillo J (ed.) Current Therapy in Critical Care Medicine. Philadelphia:BC Decker Inc. 1986.
23. Takahashi H, Wands JR. Development of monoclonal antibodies against hepatitis B virus. In: Young H, McMillan H (eds) Immunodiagnosis of Sexually Transmissible Diseases with Polyclonal and Monoclonal Antibodies. New York:Marcel Dekker Inc. 1987;451-73.
24. Wilson B, Wands JR: Recent advances in the biology and immunology of hepatitis B. In: Hodgson H (ed.) Gastrointestinal Immunology. Philadelphia:WB Saunders 1987;623-45.
25. Dienstag JD, Wands JR, Isselbacher KJ. Acute hepatitis. In: Isselbacher KJ, Petersdorf RG, Wilson JD, Martin JB, Fauci As, Braunwald E (eds). Harrison’s Principles of Internal Medicine, 12th Edition. NY:McGraw-Hill 1990;1322-37.
26. Wands JR, Isselbacher KJ. Chronic hepatitis. In: Isselbacher KJ, Petersdorf RG, Wilson JD, Martin JB, Fauci AS, Braunwald E (eds). Harrison’s Principles of Internal Medicine, 12th Edition. NY:McGraw-Hill 1990;1337-40.
27. Isselbacher KJ, Wands JR. Tumors of the liver. In: Isselbacher KJ, Petersdorf RG, Wilson JD, Martin JB, Fauci AS, Braunwald E (eds.) Harrison’s Principles of Internal Medicine, 12th Edition. NY:McGraw-Hill 1990;1350-2.
28. Blum HE, Liang TJ, Wands JR. Hepatitis B virus carrier and hepatocellular carcinoma. Falk Symposium #54 – Infectious Diseases of the Liver 1990;261-73.
29. Takahashi H, Wands JR. Studies on cell surface changes associated with transformation of human hepatocytes to the malignant phenotype and their role as potential immunotargeting sites. In: Tsuchiya M et al. (eds) Frontiers of Mucosal Immunology, Vol. 2. Holland:Elsevier Science Publ 1991;295-8.
30. Takahashi H, Wands JR. Prognosis of hepatocellular carcinoma: known to be poor, yet difficult to predict. J Nucl Med 1991;23:235-6.
31. Wands JR, Liang TJ, Blum HE, Shafritz D. The molecular pathogenesis of liver disease during persistent hepatitis B virus infection. In: Shafritz D (eds). Seminars in Liver Disease – “Impact of Recombinant DNA Techniques in Liver Disease.” NY:Thieme Med Publ 1992.
32. Hasegawa K, Wands JR. Immunology of liver diseases. In: Current Opinion in Gastroenterology. Philadelphia:Current Science 1992;8:1002-8.
33. Weizsaecker Fv, Blum H, Wands JR. Detection of low level hepatitis B and hepatitis C virus genome in alcoholics. In: Advances in the Biosciences. England:Pergamon Press 1993;86:439-48.
34. Moradpour D, Wands JR. The molecular pathogenesis of hepatocellular carcinoma. J Viral Hep 1994;1:17-31.
35. Wands JR, Bhavani K, Sasaki Y. Effect of ethanol on tyrosyl phosphorylation of growth factor receptor substrates in the liver. In: Watson RR (ed). Alcohol and Hormones NJ:Humana Press 1995;245-59.
36. Moradpour D, Wands JR. Understanding hepatitis B virus infection (editorial). N Engl J Med 1995;332-1092.
37. Moradpour D, Wands JR. Hepatic oncogenesis. In: Zakim D, Boyer T (eds). Hepatology, 3rd Edition. Philadelphia:W.B. Saunders 1996;1490-1512.
38. Scaglioni PP, Melegari M, Wands JR. Recent advances in the molecular biology of hepatitis B virus. Bailliere’s Clinical Gastroenterology:International Practice and Research. London:Bailliere Tindall 1996;10:207-25.
39. Moradpour D, Wands JR, Blum HE. Molecular biology of hepatitis B and C virus and hepatocellular carcinoma. Mol Cancer Biol 1996;3:875-904.
40. Heintges T, Wands JR. HCV: epidemiology and transmission. Hepatology 1997;27:521-6.
41. von Weiszacker F, Blum HE, Wands JR. Hammerhead ribozyme mediated cleavage of hepatitis B virus RNA. Scanlon KJ (ed). Methods in Molecular Medicine. MJ:Humana Press 1998.
42. Geissler M, Gesien A, Wands JR. Molecular mechanisms of hepatocarcinogenesis. In: Okuda K, Tabor E (eds). Liver Cancer. London:Churchill Livingstone 1997:59-88.
43. Encke J, zu Putlitz J, Wands JR. Viral hepatitis – update. DNA Vaccines. Intervirology 1999; 42:117-124.
44. zu Putlitz J, Encke J, Wands JR. The use of antisense and other molecular approaches to therapy of chronic viral hepatitis. Viral Hepatitis Reviews 1998;4:207-227.
45. Wands JR, Okuda IC. Hepatocellular Carcinoma. In: Berk PD (ed). Seminars in Liver Disease. NY:Thieme Medical Publishers 1999;19:233-4.
46. Wands JR. Hepatitis C Virus Induced Hepatocarcinogenesis. In: Dienes HP, Schirmacher P, Brechot C, Okuda K (eds.). Chronic Hepatitis: New Concepts of Pathogenesis, Diagnosis and Treatment. Boston:Kluwer Academic Publishers 2000:214-26.
47. Spangenberg H, Wands JR. Nucleic acid based antiviral approaches to HBV. In: Frontiers in Viral Hepatitis 2000
48. Wands JR, Mohr L, Banerjee K, Ganju N, Tanaka S de la Monte S. Ethanol and IRS-1 protein in the liver and brain. In: NIAAA Research Monograph-35 Ethanol and IntracellularSignaling: From Molecules to Behavior. Hoek JB, Gordon AS, Mochly-Rosen D, Zakhari S (eds.) 2001:75-104.
49. Spangenberg H, Wands JR. DNA-based vaccination, antisense strategies, and other molecular approaches. In: Textbook of Viral Hepatitis. Rio de Janeiro:Atheneu Hispanica Publ 2001.
50. Wands JR, Fukutomi T. Molecular biology and oncogenesis of hepatocellular carcinoma. In: Treatment of Liver Diseases. Arroyo V, Bosch J, Bruguera M, Rodes J, Sanchez Tapias JM (eds.). Spain:Masson Publ 2001.
51. Wiedmann M, Wands JR. Pathogenesis of hepatocellular carcinoma by hepatitis viruses. In: Hepatitis Viruses. Jing-Hsiung James Ou (ed). Kluwer Academic Publishers 2002.
52. Wands JR. Altered signal transduction in human hepatocellular carcinoma. Falk Workshop #127 Leipzig, Germany 2002: Malignant Tumours: Basic Concepts and Clinical Management. Berr F, Bruix J, Hauss J, Wands J, Wittekind Ch (Eds). The Netherlands:Kluwer Academic Publishers 2002:9 – 19.
53. Moradpour D, Wands JR. Molecular Pathogenesis of Hepatocellular Carcinoma. In: Hepatology: A Textbook of Liver Disease - 4th Edition. Zakim D and Boyer TD (eds).
PA:WB Saunders (publ). Chapter 44 –2003:1333-54.
54. Spangenberg HC, Wands JR. Nucleic acid-based antiviral approaches to HBV. In: Frontiers in Viral Hepatitis. Schinazi RF, Sommadossi JP, Rice CM (eds). Elsevier 2003:139–156.
55. Berthiaume E, Wands JR. The molecular pathogenesis of cholangiocarcinoma. In: Seminars in Liver Disease NY:Thieme Medical Publishers 2004.
56. Kim M, Wands JR. Insulin Pathway. In: Signaling pathways in liver disease. Dufour JF, Clavien PA (eds). Germany:Springer Scientific 2004
57. Promrat K, Wands JR. Aetiology of fulminant hepatitis. In: Viral Hepatitis, 3rd Edition. Thomas H, Zuckerman A, Lemon S (eds). England:Blackwell Publishing 2005;651-65.
58. Wands JR, Moradpour D. Molecular pathogenesis of hepatocellular carcinoma. In: Hepatology: A Textbook of Liver Disease – 5th Edition. Boyer, Manns & Wright (eds). PA:WB Saunders (publ.) Chapter 10-2006:
59. Kim M, Wands JR. Insulin Pathway. In: Signaling Pathways in Liver Disease. Dufour JF, Clavien PA (eds). Germany:Springer Scientific 2008.
60. Wands JR, Kim M. Signaling pathways in viral related pre-neoplastic liver disease and hepatocellular carcinoma. In: Wang XW, Grisham JW, Thorgeirsson SS (Eds). Cancer Genetics: Molecular Genetics of Liver Neoplasia. NY:Springer 2010;103-27.
61. Walker EJ, Rosenberg SA, Wands JR, Kim M. The role of raf kinase inhibitor protein in hepatocellular carcinoma. Forum on Immunopathological Disease and Therapeutics, Begell House, Inc.(Publ) 2011;2(2):195-204.
62. Shimoda M, Wands JR. Molecular biology of liver carcinogenesis and hepatitis. In: Jarnagin & Blumgart (eds). Blumgart’s Surgery of the Liver, Biliary Tree, and Pancreas. Chapter 8C 2012. Publisher: Elsevier
63. Lin C, Xu C, Wands JR. Clinical and diagnostic aspects of viral hepatitis. In: Thomas H, Zuckerman A, Lok A, Locarnini S (Eds). Viral Hepatitis 4th Edition 2013. Publisher: Wiley-Blackwell.
64. Kim M, Duendia MA, Wands JR. Hepatocellular carcinoma molecular Biology. Springer-Verlag Berlin Heidelberg 2015. Encyclopedia of Cancer 10.1007/978-3-642-27841-9_3394-2.
65. Li J, Wands JR. Hepatitis B and D viral receptors. Hepatology 2016 Jan;63(1):11-3.
66. Kim M, Wands JR. Points of therapeutic intervention along the Wnt signaling pathway in hepatocellular carcinoma. In: Advances in anti-cancer agents in medicinal chemistry. Publisher: Bentham Science 2016; 3(3):78-117.
67. Shimoda M, Wands JR. Molecular biology of liver carcinogenesis and hepatitis. In: Jarnagin & Blumgart (eds). Blumgart’s Surgery of the Liver, Biliary Tree, and Pancreas, 6th Edition. Publisher: Elsevier 2017; Vol. 1, Part 1: Chapter 9D;160-172.
| Year | Degree | Institution |
|---|---|---|
| 1969 | MD | University of Washington |
| 1965 | BS | Washington State University |
| Clinical and Research Fellow | Massachusetts General Hospital, Gastroenterology & Hepatology | 1973-1975 | |
| Clinical and Research Fellow | Harvard University, Medicine | 1973-1975 | |
| Resident | John Hopkins University, Medicine | 1971-1972 | |
| Fellow | Johns Hopkins University, Medicine | 1969-1973 |
Sigma Xi
Gin Hudson Memorial Award
Robert H. Williams Award
Graduation with Highest Thesis Honors
Clinical Investigator Awardee, National Institutes of Health, U.S. Public Health Service
Research Scientist Development Awardee, National Institutes of Health, U.S. Public Health Service
Research Scientist Awardee, National Institutes of Health, U.S. Public Health Service
N.I.H. Merit Awardee (NIAAA)
Max Planck Research Award
N.I.H. Merit Awardee (NCI)
Master of Arts, ad eundem Brown University
Bristol Myers Squibb Grant Award in Infectious Disease
Honorary Professor of Medicine, Hospital 3021 and the Medical and
Graduate schools of the PLA, Beijing, China
Fellow, American Gastroenterological Association (AGA)
Top Physician Scientist, European Research Grp, Vulpera, Switzer
Honorary Professorship of Medicine, University of Chinese Medicine at Chengdu
Honorary Professor Southern Medical University , Guangzhou, China
Honorary Professor Chongquing Medical University, Chongquin, China
Fellow, American Association Study of Liver Diseases (AASLD)
Honorary Professor Harbin Medical University, Harbin, China
Fellow, American Association for the Advancement of Science (AAAS)
| Name | Title |
|---|---|
| Bowen, Wayne | Upjohn Professor of Pharmacology, Professor Emeritus of Neuroscience, Adjunct Professor of Neuroscience, Professor of Neuroscience (Research) |
| Brossay, Laurent | Charles A. and Helen B. Stuart Professor of Medical Science, Professor of Molecular Microbiology and Immunology |
| Cao, Weibiao | Associate Professor of Pathology and Laboratory Medicine, Associate Professor of Medicine |
| Chen, Qian | Michael G. Ehrlich, MD Professor of Orthopedic Research, Professor of Medical Science |
| De La Monte, Suzanne | Professor of Pathology and Laboratory Medicine, Professor of Neurosurgery |
| Elias, Jack | Warren Alpert Foundation Professor of Translational Science, Professor of Molecular Biology, Cell Biology and Biochemistry, Professor of Medicine |
| Gruppuso, Philip | Professor of Pediatrics, Professor of Medical Science, Professor of Molecular Biology, Cell Biology and Biochemistry (Research) |
| Lee, Chun Geun | Professor of Molecular Microbiology and Immunology (Research) |
| Li, Ji | Associate Professor of Medicine (Research) |
| Moss, Steven | Professor of Medicine |
| Promrat, Kittichai | Associate Professor of Medicine |
| Resnick, Murray | Professor of Pathology and Laboratory Medicine |
| Sepe, Thomas | Clinical Professor of Medicine |
| Terek, Richard | Professor of Orthopaedics |
| Tong, Shuping | Professor of Medicine (Research) |
Sigma Xi
Johns Hopkins Medical and Surgical Society
American Association for the Study of Liver Diseases
American Federation for Clinical Research
American Association for the Advancement of Science
International Association for the Study of Liver Disease
American Gastroenterological Association
American Society for Microbiology
Founding Board Member, International Liver Cancer Association (ILCA) Barcelona
| Massachusetts | - | #36177 | |
| American Board of Internal Medicine | - | #42082 | |
| Rhode Island | - | #09974 |
| Jeffrey and Kimberly Greenberg-Artemis and Martha Joukowsky Professor in Gastroenterology and Professor of Medical Science. Alpert Medical School of Brown University, 2002- |
| Director, Division of Gastroenterology and Liver Research Center. Brown Medical School & the Lifespan Rhode Island Academic Medical Center (Rhode Island Hospital and the Miriam Hospital), 2000- |
| Adjunct Faculty. Harvard Medical School, 1999- |
| Professor of Medicine. Alpert Medical School of Brown University, 1999- |
| Professor of Medical Sciences. Brown University , 1999- |
| Member Biomedical Engineering Center. MIT, 1999- |
| Director, Molecular Hepatology Laboratory. Massachusetts General Hospital, 1988-1998 |
| Member. Massachusetts General Hospital, 1988-1998 |
| Associate Physician. Massachusetts General Hospital, 1983-1998 |
| Associate Professor in Medicine. Harvard Medical School, 1982-1998 |
| Assistant Physician. Massachusetts General Hospital, 1979-1983 |
| Assistant Professor of Medicine. Harvard Medical School, 1976-1982 |
| Instructor in Medicine. Harvard Medical School, 1975-1976 |
| Assistant in Medicine. Massachusetts General Hospital, 1975-1978 |
| Instructor in Medicine. Johns Hopkins School of Medicine, 1972-1973 |
UNIVERSITY TEACHING ROLE
Harvard Medical School
1990 – 92 Oncology Course (Lecturer)
1975 – 85 Gastrointestinal Pathophysiology (Lecturer)
1979 – 98 Gastrointestinal Pathophysiology – HST 120 (Core Faculty Member)
1998 - Revisiting Medicine – HMS 482 (Lecturer)
1999 - Gastrointestinal Pathophysiology – HST 120 (Lecturer)
Brown University
1999 Brown University Integrated Medical Science –
BioMed 195-196 Directed Research/Independent Study
1999 Brown University Integrated Medical Science –
BioMed 295-296 Graduate Independent Study
2000 - 05 Brown University Integrated Medical Science
BioMed 282 – Gastrointestinal & Liver Pathophysiology (Lecturer)
2005 Brown University Integrated Pathophysiology/Pharmacology
Bio 351 (Lecturer)
2010 Brown University Virology Course BIO 386
2012 Introduction to MCB Faculty Trainer Research BIO201A
HOSPITAL TEACHING ROLE
Massachusetts General Hospital
1985-2000 Attending Physician Bigelow Medical Service
1980-2000 Attending Physician Gastrointestinal Unit
Rhode Island
1999-2000 Gastroenterology Attending Physician
2000-2008 General Medical Service Attending
