Stefan S, Jeong KS, Polucha C, Tapinos N, Toms SA, Lee J. "Determination of confocal profile and curved focal plane for OCT mapping of the attenuation coefficient." Biomedical Optics Express, vol. 9, no. 10, 2018, pp. 5084-5099. |
"Regulation of human glioma cell migration, tumor growth, and stemness gene expression using a Lck targeted inhibitor." Oncogene, 2018. |
Martinez-Moreno M, O'Shea TM, Zepecki JP, Olaru A, Ness JK, Langer R, Tapinos N. "Regulation of Peripheral Myelination through Transcriptional Buffering of Egr2 by an Antisense Long Non-coding RNA." Cell Reports, vol. 20, no. 8, 2017, pp. 1950-1963. |
Ness JK, Skiles AA, Yap EH, Fajardo EJ, Fiser A, Tapinos N. "Nuc-ErbB3 regulates H3K27me3 levels and HMT activity to establish epigenetic repression during peripheral myelination." Glia, vol. 64, no. 6, 2016, pp. 977-92. |
Pujato M, Kieken F, Skiles AA, Tapinos N, Fiser A. "Prediction of DNA binding motifs from 3D models of transcription factors; identifying TLX3 regulated genes." Nucleic acids research, vol. 42, no. 22, 2014, pp. 13500-12. |
Ness JK, Snyder KM, Tapinos N. "Lck tyrosine kinase mediates β1-integrin signalling to regulate Schwann cell migration and myelination." Nature Communications, vol. 4, 2013, pp. 1912. |
Adilakshmi T, Ness-Myers J, Madrid-Aliste C, Fiser A, Tapinos N. "A nuclear variant of ErbB3 receptor tyrosine kinase regulates ezrin distribution and Schwann cell myelination." Journal of Neuroscience, vol. 31, no. 13, 2011, pp. 5106-19. |
Tapinos N, Ohnishi M, Rambukkana A. "ErbB2 receptor tyrosine kinase signaling mediates early demyelination induced by leprosy bacilli." Nature Medicine, vol. 12, no. 8, 2006, pp. 961-6. |
Tapinos N, Rambukkana A. "Insights into regulation of human Schwann cell proliferation by Erk1/2 via a MEK-independent and p56Lck-dependent pathway from leprosy bacilli." Proceedings of the National Academy of Sciences, vol. 102, no. 26, 2005, pp. 9188-93. |
Rambukkana A, Zanazzi G, Tapinos N, Salzer JL. "Contact-dependent demyelination by Mycobacterium leprae in the absence of immune cells." Science, vol. 296, no. 5569, 2002, pp. 927-31. |
In the Molecular Neuroscience & Neurooncology Lab we employ multidisciplinary approaches and outside-the-box thinking to discover mechanisms that regulate myelination, plasticity, cellular motility and oncogenic transformation of glial cells.
Our work in Molecular Neuro-oncology is focused on the following:
Year | Degree | Institution |
---|---|---|
2000 | PhD | University of Athens |
1996 | MD | University of Athens |
Name | Title |
---|---|
Anthony, Douglas | Professor of Pathology and Laboratory Medicine, Professor of Neurology |
Elias, Jack | Warren Alpert Foundation Professor of Translational Science, Professor of Molecular Biology, Cell Biology and Biochemistry, Senior Vice President of Health Affairs, Chief of Translational Medicine, Professor of Medicine |
Lee, Jonghwan | Assistant Professor of Engineering |
Morgan, Jeffrey | Professor of Pathology and Laboratory Medicine, Donna Weiss '89 and Jason Weiss Director of the Center for Alternatives to Animals in Testing, Professor of Engineering |
Webb, Ashley | Richard and Edna Salomon Assistant Professor of Molecular Biology, Cell Biology and Biochemistry |
Wong, Ian | Assistant Professor of Engineering, Assistant Professor of Pathology and Laboratory Medicine |