Orestis Panagiotou is a physician-scientist with experience in evidence-based medicine, clinical epidemiology, and research methodology. He received his MD and PhD in Epidemiology from the University of Ioannina in Greece and completed a post-doctoral fellowship in Epidemiology and Biostatistics at the National Cancer Institute in Bethesda, MD.
His research interests include comparative effectiveness and safety research and risk prediction, particularly in the context of routinely-collected health data. To this end, Orestis works on both applied and methodological problems in the following research areas:
| Panagiotou OA, Markozannes G, Adam GP, Kowalski R, Gazula A, Di M, Bond DS, Ryder BA, Trikalinos TA Comparative Effectiveness and Safety of Bariatric Procedures in Medicare-Eligible Patients: A Systematic Review.. JAMA Surgery. 2018; 153 (11) : e183326. |
| Trivedi AN, Leyva B, Lee Y, Panagiotou OA, Dahabreh IJ Elimination of Cost Sharing for Screening Mammography in Medicare Advantage Plans.. New England Journal of Medicine. 2018; 378 (3) : 262-269. |
| Koster R, Panagiotou OA, Wheeler WA, Karlins E, Gastier-Foster JM, Caminada de Toledo SR, Petrilli AS, Flanagan AM, Tirabosco R, Andrulis IL, Wunder JS, Gokgoz N, Patiño-Garcia A, Lecanda F, Serra M, Hattinger C, Picci P, Scotlandi K, Thomas DM, Ballinger ML, Gorlick R, Barkauskas DA, Spector LG, Tucker M, Belynda DH, Yeager M, Hoover RN, Wacholder S, Chanock SJ, Savage SA, Mirabello L Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients.. International Journal of Cancer. 2017; 142 (8) : 1594-1601. |
| Doufas AG, Panagiotou OA, Panousis P, Wong SS, Ioannidis JP Insomnia From Drug Treatments: Evidence From Meta-analyses of Randomized Trials and Concordance With Prescribing Information.. Mayo Clinic proceedings. 2017; 92 (1) : 72-87. |
| Huang J, Panagiotou OA, Anic GM, Mondul AM, Liao LM, Derkach A, Stolzenberg-Solomon R, Weinstein SJ, Albanes D Metabolomic Profiling of Serum Retinol in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study.. Scientific reports. 2017; 7 (1) : 10601. |
| Schuit E, Panagiotou OA, Munafò MR, Bennett DA, Bergen AW, David SP Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers.. The Cochrane database of systematic reviews. 2017; 9 : CD011823. |
| Contopoulos-Ioannidis D, Tseretopoulou X, Ancker M, Walterspiel JN, Panagiotou OA, Maldonado Y, Ioannidis JP Comparative rates of harms in randomized trials from more developed versus less developed countries may be different.. American Journal of Kidney Diseases. 2016; 78 : 10-21. |
| Harari A, Chen Z, Rodríguez AC, Hildesheim A, Porras C, Herrero R, Wacholder S, Panagiotou OA, Befano B, Burk RD, Schiffman M, Costa Rica HPV Vaccine Trial Group Cross-protection of the Bivalent Human Papillomavirus (HPV) Vaccine Against Variants of Genetically Related High-Risk HPV Infections.. Journal of Infectious Diseases. 2016; 213 (6) : 939-47. |
| Nelson SM, Panagiotou OA, Anic GM, Mondul AM, Männistö S, Weinstein SJ, Albanes D Metabolomics analysis of serum 25-hydroxy-vitamin D in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study.. International journal of epidemiology. 2016; 45 (5) : 1458-1468. |
| Li Y, Panagiotou OA, Black A, Liao D, Wacholder S Multivariate piecewise exponential survival modeling.. Biometrics. 2016; 72 (2) : 546-53. |
| Panagiotou OA One Author Replies.. American Journal of Epidemiology. 2016; 183 (10) : 958-9. |
| Panagiotou OA, Travis RC, Campa D, Berndt SI, Lindstrom S, Kraft P, Schumacher FR, Siddiq A, Papatheodorou SI, Stanford JL, Albanes D, Virtamo J, Weinstein SJ, Diver WR, Gapstur SM, Stevens VL, Boeing H, Bueno-de-Mesquita HB, Barricarte Gurrea A, Kaaks R, Khaw KT, Krogh V, Overvad K, Riboli E, Trichopoulos D, Giovannucci E, Stampfer M, Haiman C, Henderson B, Le Marchand L, Gaziano JM, Hunter DJ, Koutros S, Yeager M, Hoover RN, PRACTICAL Consortium, Chanock SJ, Wacholder S, Key TJ, Tsilidis KK A genome-wide pleiotropy scan for prostate cancer risk.. European urology. 2015; 67 (4) : 649-57. |
| Mirabello L, Koster R, Moriarity BS, Spector LG, Meltzer PS, Gary J, Machiela MJ, Pankratz N, Panagiotou OA, Largaespada D, Wang Z, Gastier-Foster JM, Gorlick R, Khanna C, de Toledo SR, Petrilli AS, Patiño-Garcia A, Sierrasesúmaga L, Lecanda F, Andrulis IL, Wunder JS, Gokgoz N, Serra M, Hattinger C, Picci P, Scotlandi K, Flanagan AM, Tirabosco R, Amary MF, Halai D, Ballinger ML, Thomas DM, Davis S, Barkauskas DA, Marina N, Helman L, Otto GM, Becklin KL, Wolf NK, Weg MT, Tucker M, Wacholder S, Fraumeni JF Jr, Caporaso NE, Boland JF, Hicks BD, Vogt A, Burdett L, Yeager M, Hoover RN, Chanock SJ, Savage SA A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma.. Cancer discovery. 2015; 5 (9) : 920-31. |
| Belbasis L, Panagiotou OA, Dosis V, Evangelou E A systematic appraisal of field synopses in genetic epidemiology: a HuGE review.. American Journal of Epidemiology. 2015; 181 (1) : 1-16. |
| Sampson JN, Wheeler WA, Yeager M, Panagiotou O, Wang Z, Berndt SI, Lan Q, Abnet CC, Amundadottir LT, Figueroa JD, Landi MT, Mirabello L, Savage SA, Taylor PR, De Vivo I, McGlynn KA, Purdue MP, Rajaraman P, Adami HO, Ahlbom A, Albanes D, Amary MF, An SJ, Andersson U, Andriole G Jr, Andrulis IL, Angelucci E, Ansell SM, Arici C, Armstrong BK, Arslan AA, Austin MA, Baris D, Barkauskas DA, Bassig BA, Becker N, Benavente Y, Benhamou S, Berg C, Van Den Berg D, Bernstein L, Bertrand KA, Birmann BM, Black A, Boeing H, Boffetta P, Boutron-Ruault MC, Bracci PM, Brinton L, Brooks-Wilson AR, Bueno-de-Mesquita HB, Burdett L, Buring J, Butler MA, Cai Q, Cancel-Tassin G, Canzian F, Carrato A, Carreon T, Carta A, Chan JK, Chang ET, Chang GC, Chang IS, Chang J, Chang-Claude J, Chen CJ, Chen CY, Chen C, Chen CH, Chen C, Chen H, Chen K, Chen KY, Chen KC, Chen Y, Chen YH, Chen YS, Chen YM, Chien LH, Chirlaque MD, Choi JE, Choi YY, Chow WH, Chung CC, Clavel J, Clavel-Chapelon F, Cocco P, Colt JS, Comperat E, Conde L, Connors JM, Conti D, Cortessis VK, Cotterchio M, Cozen W, Crouch S, Crous-Bou M, Cussenot O, Davis FG, Ding T, Diver WR, Dorronsoro M, Dossus L, Duell EJ, Ennas MG, Erickson RL, Feychting M, Flanagan AM, Foretova L, Fraumeni JF Jr, Freedman ND, Beane Freeman LE, Fuchs C, Gago-Dominguez M, Gallinger S, Gao YT, Gapstur SM, Garcia-Closas M, García-Closas R, Gascoyne RD, Gastier-Foster J, Gaudet MM, Gaziano JM, Giffen C, Giles GG, Giovannucci E, Glimelius B, Goggins M, Gokgoz N, Goldstein AM, Gorlick R, Gross M, Grubb R 3rd, Gu J, Guan P, Gunter M, Guo H, Habermann TM, Haiman CA, Halai D, Hallmans G, Hassan M, Hattinger C, He Q, He X, Helzlsouer K, Henderson B, Henriksson R, Hjalgrim H, Hoffman-Bolton J, Hohensee C, Holford TR, Holly EA, Hong YC, Hoover RN, Horn-Ross PL, Hosain GM, Hosgood HD 3rd, Hsiao CF, Hu N, Hu W, Hu Z, Huang MS, Huerta JM, Hung JY, Hutchinson A, Inskip PD, Jackson RD, Jacobs EJ, Jenab M, Jeon HS, Ji BT, Jin G, Jin L, Johansen C, Johnson A, Jung YJ, Kaaks R, Kamineni A, Kane E, Kang CH, Karagas MR, Kelly RS, Khaw KT, Kim C, Kim HN, Kim JH, Kim JS, Kim YH, Kim YT, Kim YC, Kitahara CM, Klein AP, Klein RJ, Kogevinas M, Kohno T, Kolonel LN, Kooperberg C, Kricker A, Krogh V, Kunitoh H, Kurtz RC, Kweon SS, LaCroix A, Lawrence C, Lecanda F, Lee VH, Li D, Li H, Li J, Li YJ, Li Y, Liao LM, Liebow M, Lightfoot T, Lim WY, Lin CC, Lin D, Lindstrom S, Linet MS, Link BK, Liu C, Liu J, Liu L, Ljungberg B, Lloreta J, Di Lollo S, Lu D, Lund E, Malats N, Mannisto S, Le Marchand L, Marina N, Masala G, Mastrangelo G, Matsuo K, Maynadie M, McKay J, McKean-Cowdin R, Melbye M, Melin BS, Michaud DS, Mitsudomi T, Monnereau A, Montalvan R, Moore LE, Mortensen LM, Nieters A, North KE, Novak AJ, Oberg AL, Offit K, Oh IJ, Olson SH, Palli D, Pao W, Park IK, Park JY, Park KH, Patiño-Garcia A, Pavanello S, Peeters PH, Perng RP, Peters U, Petersen GM, Picci P, Pike MC, Porru S, Prescott J, Prokunina-Olsson L, Qian B, Qiao YL, Rais M, Riboli E, Riby J, Risch HA, Rizzato C, Rodabough R, Roman E, Roupret M, Ruder AM, Sanjose Sd, Scelo G, Schned A, Schumacher F, Schwartz K, Schwenn M, Scotlandi K, Seow A, Serra C, Serra M, Sesso HD, Setiawan VW, Severi G, Severson RK, Shanafelt TD, Shen H, Shen W, Shin MH, Shiraishi K, Shu XO, Siddiq A, Sierrasesúmaga L, Sihoe AD, Skibola CF, Smith A, Smith MT, Southey MC, Spinelli JJ, Staines A, Stampfer M, Stern MC, Stevens VL, Stolzenberg-Solomon RS, Su J, Su WC, Sund M, Sung JS, Sung SW, Tan W, Tang W, Tardón A, Thomas D, Thompson CA, Tinker LF, Tirabosco R, Tjønneland A, Travis RC, Trichopoulos D, Tsai FY, Tsai YH, Tucker M, Turner J, Vajdic CM, Vermeulen RC, Villano DJ, Vineis P, Virtamo J, Visvanathan K, Wactawski-Wende J, Wang C, Wang CL, Wang JC, Wang J, Wei F, Weiderpass E, Weiner GJ, Weinstein S, Wentzensen N, White E, Witzig TE, Wolpin BM, Wong MP, Wu C, Wu G, Wu J, Wu T, Wu W, Wu X, Wu YL, Wunder JS, Xiang YB, Xu J, Xu P, Yang PC, Yang TY, Ye Y, Yin Z, Yokota J, Yoon HI, Yu CJ, Yu H, Yu K, Yuan JM, Zelenetz A, Zeleniuch-Jacquotte A, Zhang XC, Zhang Y, Zhao X, Zhao Z, Zheng H, Zheng T, Zheng W, Zhou B, Zhu M, Zucca M, Boca SM, Cerhan JR, Ferri GM, Hartge P, Hsiung CA, Magnani C, Miligi L, Morton LM, Smedby KE, Teras LR, Vijai J, Wang SS, Brennan P, Caporaso NE, Hunter DJ, Kraft P, Rothman N, Silverman DT, Slager SL, Chanock SJ, Chatterjee N Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types.. JNCI Journal of the National Cancer Institute. 2015; 107 (12) : djv279. |
| Panagiotou OA, Trikalinos TA Commentary: On Effect Measures, Heterogeneity, and the Laws of Nature.. Epidemiology. 2015; 26 (5) : 710-3. |
| Panagiotou OA, Befano BL, Gonzalez P, Rodríguez AC, Herrero R, Schiller JT, Kreimer AR, Schiffman M, Hildesheim A, Wilcox AJ, Wacholder S, Costa Rica HPV Vaccine Trial (CVT) Group (see end of manuscript for full list of investigators) Effect of bivalent human papillomavirus vaccination on pregnancy outcomes: long term observational follow-up in the Costa Rica HPV Vaccine Trial.. BMJ. 2015; 351 : h4358. |
| Flegal KM, Panagiotou OA, Graubard BI Estimating population attributable fractions to quantify the health burden of obesity.. Annals of Epidemiology. 2015; 25 (3) : 201-7. |
| Panagiotou OA Network Meta-Analysis: Evidence Synthesis With Mixed Treatment Comparison.. American Journal of Epidemiology. 2015; |
| Guertin KA, Gu F, Wacholder S, Freedman ND, Panagiotou OA, Reyes-Guzman C, Caporaso NE Time to First Morning Cigarette and Risk of Chronic Obstructive Pulmonary Disease: Smokers in the PLCO Cancer Screening Trial.. PLoS ONE. 2015; 10 (5) : e0125973. |
| Panagiotou OA, Wacholder S Invited commentary: How big is that interaction (in my community)--and in which direction?. American Journal of Epidemiology. 2014; 180 (12) : 1150-8. |
| Gu F, Wacholder S, Freedman ND, Panagiotou OA, Reyes-Guzman C, Bertazzi PA, Caporaso NE Response.. JNCI Journal of the National Cancer Institute. 2014; 106 (12) |
| Lathyris D, Panagiotou OA, Baltogianni M, Ioannidis JP, Contopoulos-Ioannidis DG Safety of medical interventions in children versus adults.. PEDIATRICS. 2014; 133 (3) : e666-73. |
| Gu F, Wacholder S, Kovalchik S, Panagiotou OA, Reyes-Guzman C, Freedman ND, De Matteis S, Consonni D, Bertazzi PA, Bergen AW, Landi MT, Caporaso NE Time to smoke first morning cigarette and lung cancer in a case-control study.. JNCI Journal of the National Cancer Institute. 2014; 106 (6) : dju118. |
| Panagiotou OA, Contopoulos-Ioannidis DG, Ioannidis JP Comparative effect sizes in randomised trials from less developed and more developed countries: meta-epidemiological assessment.. BMJ. 2013; 346 : f707. |
| Tsilidis KK, Panagiotou OA, Sena ES, Aretouli E, Evangelou E, Howells DW, Al-Shahi Salman R, Macleod MR, Ioannidis JP Evaluation of excess significance bias in animal studies of neurological diseases.. PLoS biology. 2013; 11 (7) : e1001609. |
| Yioti GG, Panagiotou OA, Vartholomatos GA, Kolaitis NI, Pappa CN, Evangelou E, Stefaniotou MI Genetic polymorphisms associated with retinal vein occlusion: a Greek case-control study and meta-analysis.. Ophthalmic genetics. 2013; 34 (3) : 130-9. |
| Stefanaki I, Panagiotou OA, Kodela E, Gogas H, Kypreou KP, Chatzinasiou F, Nikolaou V, Plaka M, Kalfa I, Antoniou C, Ioannidis JP, Evangelou E, Stratigos AJ Replication and predictive value of SNPs associated with melanoma and pigmentation traits in a Southern European case-control study.. PLoS ONE. 2013; 8 (2) : e55712. |
| Panagiotou OA, Willer CJ, Hirschhorn JN, Ioannidis JP The power of meta-analysis in genome-wide association studies.. Annual review of genomics and human genetics. 2013; 14 : 441-65. |
| Doufas AG, Panagiotou OA, Ioannidis JP Concordance of sleep and pain outcomes of diverse interventions: an umbrella review.. PLoS ONE. 2012; 7 (7) : e40891. |
| Panagiotou OA, Ioannidis JP Primary study authors of significant studies are more likely to believe that a strong association exists in a heterogeneous meta-analysis compared with methodologists.. American Journal of Kidney Diseases. 2012; 65 (7) : 740-7. |
| Panagiotou OA, Ioannidis JP, Genome-Wide Significance Project What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations.. International journal of epidemiology. 2012; 41 (1) : 273-86. |
| Ioannidis JP, Panagiotou OA Comparison of effect sizes associated with biomarkers reported in highly cited individual articles and in subsequent meta-analyses.. JAMA. 2011; 305 (21) : 2200-10. |
| Panagiotou OA, Contopoulos-Ioannidis DG, Papanikolaou PN, Ntzani EE, Ioannidis JP Different black box warning labeling for same-class drugs.. J GEN INTERN MED. 2011; 26 (6) : 603-10. |
| Panagiotou OA, Evangelou E, Ioannidis JP Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.. American Journal of Epidemiology. 2010; 172 (8) : 869-89. |
| Year | Degree | Institution |
|---|---|---|
| 2014 | PhD | University of Ioannina |
| 2009 | MD | University of Ioannina |
| Name | Title |
|---|---|
| Balk, Ethan | Associate Professor of Health Services, Policy and Practice (Research) |
| Belanger, Emmanuelle | Assistant Professor of Health Services, Policy and Practice |
| Gareen, Ilana | Associate Professor of Epidemiology (Research) |
| Gatsonis, Constantine | Henry Ledyard Goddard University Professor of Statistical Sciences, Director of Statistical Sciences, Professor of Biostatistics |
| Gozalo, Pedro | Associate Professor of Health Services, Policy and Practice (Research) |
| Gutman, Roee | Associate Professor of Biostatistics |
| Mor, Vincent | Florence Pirce Grant University Professor, Professor of Health Services, Policy and Practice |
| Olszewski, Adam | Assistant Professor of Medicine |
| Shireman, Theresa | Professor of Health Services, Policy and Practice |
| Trikalinos, Thomas | Associate Professor of Health Services, Policy and Practice, Director of the Center for Evidence Synthesis in Health |
| Trivedi, Amal | Associate Professor of Health Services, Policy and Practice, Associate Professor of Medicine |
Society for Epidemiologic Research
American College of Epidemiology
American Statistical Association
American Association for Cancer Research
