Our lab's work focuses on developing and applying magnetic resonance imaging (MRI) techniques to study early brain development. Our current studies involve following the process of myelination in healthy infants and toddlers in relationship to behavioural development and exploring the varied environmental and genetic influences that shape these brain-behaviour relationships.
|Remer J, Croteau-Chonka E, Dean DC 3rd, D'Arpino S, Dirks H, Whiley D, Deoni SCL Quantifying cortical development in typically developing toddlers and young children, 1-6 years of age.. NeuroImage. 2017; 153 : 246-261.|
|Kurth S, Dean DC 3rd, Achermann P, O'Muircheartaigh J, Huber R, Deoni SC, LeBourgeois MK Increased Sleep Depth in Developing Neural Networks: New Insights from Sleep Restriction in Children.. Frontiers in human neuroscience. 2016; 10 : 456.|
|Dean DC 3rd, O'Muircheartaigh J, Dirks H, Travers BG, Adluru N, Alexander AL, Deoni SCL Mapping an index of the myelin g-ratio in infants using magnetic resonance imaging.. NeuroImage. 2016; 132 : 225-237.|
|Stence NV, Mirsky DM, Deoni SC, Armstrong-Wells J Paradoxical centrally increased diffusivity in perinatal arterial ischemic stroke.. Pediatr Radiol. 2016; 46 (1) : 82-6.|
|Deoni SC, O'Muircheartaigh J, Elison JT, Walker L, Doernberg E, Waskiewicz N, Dirks H, Piryatinsky I, Dean DC 3rd, Jumbe NL White matter maturation profiles through early childhood predict general cognitive ability.. Brain Struct Funct. 2016; 221 (2) : 1189-203.|
|Deoni SC, Dean DC 3rd, Remer J, Dirks H, O'Muircheartaigh J Cortical maturation and myelination in healthy toddlers and young children.. NeuroImage. 2015; 115 : 147-61.|
|Dean DC 3rd, O'Muircheartaigh J, Dirks H, Waskiewicz N, Lehman K, Walker L, Piryatinsky I, Deoni SC Estimating the age of healthy infants from quantitative myelin water fraction maps. Human Brain Mapping. 2015; 36 (4) : 1233-1244.|
|Chevalier N, Kurth S, Doucette MR, Wiseheart M, Deoni SC, Dean DC 3rd, O'Muircheartaigh J, Blackwell KA, Munakata Y, LeBourgeois MK Myelination Is Associated with Processing Speed in Early Childhood: Preliminary Insights.. PLoS ONE. 2015; 10 (10) : e0139897.|
|Deoni SC, Zinkstok JR, Daly E, Ecker C, MRC AIMS Consortium., Williams SC, Murphy DG White-matter relaxation time and myelin water fraction differences in young adults with autism.. Psychological Medicine. 2015; 45 (4) : 795-805.|
|Dean, Douglas C., O’Muircheartaigh, Jonathan, Dirks, Holly, Waskiewicz, Nicole, Walker, Lindsay, Doernberg, Ellen, Piryatinsky, Irene, Deoni, Sean C. L. Characterizing longitudinal white matter development during early childhood.. Brain Struct Funct. 2014; 220 (4) : 1921-33.|
|Deoni, Sean C.L., Dean, Douglas C., Walker, Lindsay, Dirks, Holly, O'Muircheartaigh, Jonathan Nutritional influences on early white matter development: Response to Anderson and Burggren. NeuroImage/NeuroImage. 2014; 100 : 703-705.|
|O'Muircheartaigh, Jonathan, Dean, Douglas C., Ginestet, Cedric E., Walker, Lindsay, Waskiewicz, Nicole, Lehman, Katie, Dirks, Holly, Piryatinsky, Irene, Deoni, Sean C.L. White matter development and early cognition in babies and toddlers. Human Brain Mapping/Human Brain Mapping. 2014; 35 (9) : 4475-4487.|
Deoni SCL, Mercure E, Blasi A, Gasston D, Thomspon A, Johnson M, Williams SC, Murphy DG. Mapping Infant Brain Myelination with Magnetic Resonance Imaging. J. Neurosci. 31: 784-791 (2011).
Memorial Hospital of Rhode Island
Director of MRI Research