Timothy P. Murphy Professor of Diagnostic Imaging

Timothy Murphy, MD, is the medical director of the Vascular Disease Research Center. Murphy is a an interventional radiologist at Rhode Island Hospital and a professor, research track, in the department of diagnostic imaging at Brown Medical School.

Murphy completed the six-year Medical Education Program at Boston University in 1987, and has been on staff at Rhode Island Hospital since 1993. He has been performing and publishing his clinical and laboratory research for 18 years. Murphy has helped secure commitments for over $35 million in total National Institutes of Health (NIH) funding for clinical trials in vascular disease.

Brown Affiliations

scholarly work

Dworkin L, Murphy TP. Is There Any Reason to Stent Atherosclerotic Renal Artery Stenosis? Am J Kid Dis, in press.

Murphy TP, Dhangana R, Pencina MJ, D'Agostino RB. Ankle-brachial index and cardiovascular risk prediction: an analysis of 11,594 individuals with 10-year follow-up. Atherosclerosis. 2012 Jan;220(1):160-7. PMID: 22099055

Murphy TP, Cutlip DE, Regensteiner JG, Mohler ER, Cohen DJ, Reynolds MR, Massaro JM, Lewis BA, Cerezo J, Oldenburg NC, Thum CC, Goldberg S, Jaff MR, Steffes MW, Comerota AJ, Ehrman J, Treat-Jacobson D, Walsh ME, Collins T, Badenhop DT, Bronas U, Hirsch AT; CLEVER Study Investigators. Supervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease: six-month outcomes from the claudication: exercise versus endoluminal revascularization (CLEVER) Study. Circulation. 2012 Jan 3;125(1):130-9. PMID: 22090168

Murphy TP, Kuo MD, Benenati JF, Dixon RG, Goodwin SC, Hicks M, Miller DL, Sidhu MK, Silberzweig JE, Vedantham S, Cardella JF; Society of Interventional Radiology. Position statement by the Society of Interventional Radiology: maintenance of privileges for image-guided interventions. J Vasc Interv Radiol. 2011 Oct;22(10):1353-4.

Dhangana R, Murphy TP, Coll JR, Ahn SH, Zafar AM, Qadeer FF, Hiatt WR. Prevalence of abnormal ankle-brachial index among individuals with low or intermediate framingham risk scores. J Vasc Interv Radiol. 2011 Aug;22(8):1077-82. Epub 2011 Jun 25. PMID: 21705232

Zafar AM, Dhangana R, Murphy TP, Goodwin SC, Duszak R. Jr., Ray C. Jr., Manolov NE. Lower Extremity Endovascular Interventions for Medicare Beneficiaries: Comparative Effectiveness as a Function of Provider Specialty. J Vasc Interv Radiol, J Vasc Interv Radiol. 2011 Nov 21. [Epub ahead of print]. PMID: 22217499

Murphy TP, Dhangana R, Pencina MJ, Zafar AM, D'Agostino RB. Performance of current guidelines for coronary heart disease prevention: optimal use of the Framingham-based risk assessment. Atherosclerosis. 2011 Jun;216(2):452-7. PMID: 21411089

Zafar AM, Harris TJ, Murphy TP, Machan JT. Patients' perspective about risks and benefits of treatment for peripheral arterial disease. J Vasc Interv Radiol. 2011;22(12):1657-61.

Murphy TP, Spronk S, de Ridder M, Lesaffre EM. Primary end-point error. Radiology. 2010 Sep;256(3):1011; author reply 1011-2. No abstract available. PMID: 20720082

Golzarian J, Sapoval MR, Kundu S, Hunter DW, Brountzos EN, Geschwind JF, Murphy TP, Spies JB, Wallace MJ, de Baere T, Cardella JF. Guidelines for Peripheral and Visceral Vascular Embolization Training: joint writing groups of the Standards of Practice Committees for the Society of Interventional Radiology (SIR), Cardiovascular and Interventional Radiological Society of Europe (CIRSE), and Canadian Interventional Radiology Association (CIRA); Society of Interventional Radiology (SIR); Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Canadian Interventional Radiology Association (CIRA). J Vasc Interv Radiol. 2010 Apr;21(4):436-41. PMID: 20346881

Baerlocher MO, Munk PL, Radvany MG, Murphy TP, Murphy KJ.Vertebroplasty, research design, and critical analysis.J Vasc Interv Radiol. 2009 Oct;20(10):1277-8.

Schirmang TC, Ahn SH, Murphy TP, Dubel GJ, Soares GM. Peripheral Arterial Disease: Update of Overview and Treatment. Medicine & Health Rhode Island 2009;92(12):398-406.

Murphy TP, Hirsch AT, Cutlip DE, Regensteiner JG, Comerota AJ, Mohler E, Cohen DJ, Massaro J. Claudication: Exercise Vs. Endoluminal Revascularization (CLEVER) Study Update. J Vasc Surg. 2009 Oct;50(4):942-945.

Bronas UG, Hirsch AT, Murphy T, Badenhop D, Collins TC, Ehrman JK, Ershow AG, Lewis B, Treat-Jacobson DJ, Walsh ME, Oldenburg N, Regensteiner JG; CLEVER Research Group. Design of the multicenter standardized supervised exercise training intervention for the claudication: exercise vs endoluminal revascularization (CLEVER) study. Vasc Med. 2009 Nov;14(4):313-21.

Conklin PC, Soares GM, Dubel GJ, Ahn SH, Murphy TP. Acute Deep Vein Thrombosis (DVT): Evolving Treatment Strategies and Endovascular Therapy. Medicine & Health Rhode Island 2009;92(12):394-7.

Cooper CJ, Haller ST, Colyer W, Steffes M, Burket MW, Thomas WJ, Safian R, Reddy B, Brewster P, Ankenbrandt MA, Virmani R, Dippel E, Rocha-Singh K, Murphy TP, Kennedy DJ, Shapiro JI, D'Agostino RD, Pencina MJ, Khuder S. Embolic protection and platelet inhibition during renal artery stenting.Circulation 2008;117(21):2752-60.

Murphy TP, Hirsch AT, Ricotta JJ, Cutlip DE, Mohler E, Regensteiner JG, Comerota AJ, Cohen DJ; CLEVER Steering Committee. The Claudication: Exercise Vs. Endoluminal Revascularization (CLEVER) study: Rationale and methods. J Vasc Surg. 2008 Jun;47(6):1356-1363.

Shlansky-Goldberg RD, Matsumoto AH, Baumbach GA, Siegel JB, Raabe RD, Murphy TP, Deng C, Ray Dawkins J, Marder VJ.A first-in-human phase I trial of locally delivered human plasmin for hemodialysis graft occlusion. J Thromb Haemost 2008;6(6):944-50.

Calhoun DA, Jones D, Textor S, Goff DC, Murphy TP, Toto RD, White A, Cushman WC, White W, Sica D, Ferdinand K, Giles TD, Falkner B, Carey RM; American Heart Association Professional Education Committee. Resistant hypertension: diagnosis, evaluation, and treatment: a scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Circulation. 2008 Jun 24;117(25):e510-26.

Calhoun DA, Jones D, Textor S, Goff DC, Murphy TP, Toto RD, White A, Cushman WC, White W, Sica D, Ferdinand K, Giles TD, Falkner B, Carey RM.Resistant hypertension: diagnosis, evaluation, and treatment: a scientific statement from the american heart association professional education committee of the council for high blood pressure research. Hypertension 2008;51(6):1403-19.

Dubel GJ, Murphy TP. The role of percutaneous revascularization for renal artery stenosis. Vasc Med. 2008;13(2):141-56.

Cooper CJ, Haller ST, Colyer W, Steffes M, Burket MW, Thomas WJ, Safian R, Reddy B, Brewster P, Virmani R, Dippel E, Rocha-Singh K, Murphy TP, Kennedy D, Shapiro J, Khuder S. Embolic protection and platelet inhibition during renal artery stenting. Circulation. 2008 May 27;117(21):2752-60.

Prince EA, Murphy TP, Dhangana R, Soares GM, Ahn SH, Dubel GJ.Evaluation and management of patients with peripheral artery disease by interventional radiologists: current practices. J Vasc Interv Radiol. 2008 May;19(5):639-44.

Dubel GJ, Murphy TP. Distal embolic protection for renal arterial interventions. Cardiovasc Intervent Radiol 2008;31(1):14-22.

Murphy TP. Critical mass: the potential role of the mega-group to address the manpower shortage and facilitate office-based practice in interventional radiology. J Vasc Interv Radiol. 2007 May;18(5):587-9.

Murphy TP, Dubel G, Bass J, Ahn S, Sores GM, Cerezo J. Spot Light on Claudication: An Important Disease Gets Attention. Medicine & Health Rhode Island 2007;90(2):40-42.

Hirsch AT, Murphy TP, Lovell MB, Twillman G, Treat-Jacobson D, Harwood EM, Mohler ER 3rd, Creager MA, Hobson RW 2nd, Robertson RM, Howard WJ, Schroeder P, Criqui MH; Peripheral Arterial Disease Coalition.Gaps in public knowledge of peripheral arterial disease: the first national PAD public awareness survey.Circulation. 2007 Oct 30;116(18):2086-94.

Cooper CJ, Murphy TP. Is renal artery stenting the correct treatment of renal artery stenosis? The case for renal artery stenting for treatment of renal artery stenosis. Circulation. 2007;115(2):263-9; discussion 270.

Soares GM, Murphy TP, Singha MS, Parada A, Jaff M. Renal artery duplex ultrasonography as a screening and surveillance tool to detect renal artery stenosis: a comparison with current reference standard imaging. J Ultrasound Med. 2006 Mar;25(3):293-8.

Cooper CJ, Murphy TP, Dworkin L, et al. Stent Revascularization for the Prevention of Cardiovascular and Renal Events Among Patients with Renal Artery Stenosis and Systolic Hypertension: Rationale and Design of the CORAL Trial. Am Heart J. 2006 Jul;152(1):59-66.

Khan N, Soares GM, Murphy TP. Bowel entrapment in comminuted iliac wing fracture. Medicine and Health, Rhode Island 2005;88(5):163.

Murphy TP, Soares GM, Kim HM, Ahn SH, Raas RA. Quality-of-Life and Exercise Performance After Aortoiliac Stent Placement for Claudication. J Vasc Interv Radiol. 2005 Jul;16(7):947-53.

Khan N, Murphy TP, Haas RA, Soares GM, Dubel GJ. Stroke prevention. Med Health R I. 2005 Feb;88(2):44-7.

Khan N, Murphy TP, Haas RA, Soares GM, Dubel GJ. Stroke prevention. Rhode Island Medicine and Health 2005;88(2):44-47.

Murphy TP. American College of Radiology Practice Guideline for Interventional Clinical Practice: a commitment to patient care. J Vasc Interv Radiol 2005;16(2 Pt 1):157-9.

Beland MD, Soares GM, Dubel GJ, Forte MP, Murphy TP. Endovascular repair of a thoracic aorta mycotic pseudoaneurysm in a patient with history of bacteroides fragilis sepsis and leprosy. J Vasc Interv Radiol 2005;16(2 Pt 1):298-300.

Khan N, Murphy TP, Dubel GJ. Carotid artery stenting with distal protection device. Medicine and Health Rhode Island 2005;88(3):96.

Murphy TP. Comparing the SMART stent with the Wallstent iliac endoprosthesis: reading between the lines. J Vasc Interv Radiol. 2004;15(9):907-9.

Murphy TP, Ariaratnam NS, Carney WI, Marcaccio EJ, Slaiby JM, Soares GM. Long-term experience with stent treatment of aortoiliac insufficiency. Radiology 2004; 231(1): 243-249.

Murphy TP. Clinical interventional radiology: serving the patient. J Vasc Interv Radiol 2003;14(4):401-3.

Rundback JH, Sacks D, Kent KC, Cooper C, Jones D, Murphy T, Rosenfield K, White C, Bettmann M, Cortell S, Puschett J, Clair DG, Cole P; Councils on Cardiovascular Radiology, High Blood Pressure Research, Kidney in Cardiovascular Disease, and Clinical Cardiology, American Heart Association; FDA Device Forum Committee, Society of Interventional Radiology. Guidelines for the reporting of renal artery revascularization in clinical trials. J Vasc Interv Radiol. 2003;14(9 Pt 2):S477-92.

Leighton DB, Ahn SH, Murphy TP. SIR 2003 film panel case 2: tumor emboli to the common iliac arteries. J Vasc Interv Radiol. 2003 May;14(5):656-8.

Murphy TP, Rundback JH, Cooper C, Kiernan MS. Chronic renal ischemia: implications for cardiovascular disease risk. J Vasc Interv Radiol 2002;13(12):1187-98.

Rundback JH, Sacks D, Kent KC, Cooper C, Jones D, Murphy T, Rosenfield K, White C, Bettmann M, Cortell S, Puschett J, Clair D, Cole P. Guidelines for the Reporting of Renal Artery Revascularization in Clinical Trials. J Vasc Interv Radiol 2002;13:959-974.

Rundback JH, Sacks D, Kent KC, Cooper C, Jones D, Murphy T, Rosenfield K, White C, Bettmann M, Cortell S, Puschett J, Clair D, Cole P. Guidelines for the reporting of renal artery revascularization in clinical trials. American Heart Association. Circulation 2002;106(12):1572-85.

Rundback JH, Murphy TP, Cooper C, Weintraub JL. Chronic renal ischemia: pathophysiologic mechanisms of cardiovascular and renal disease. J Vasc Interv Radiol 2002;13(11):1085-92.

Ahn SH, Cutry A, Murphy TP, Slaiby JM. Traumatic thoracic aortic rupture: treatment with endovascular graft in the acute setting. J Trauma. 2001;50(5):949-51.

Harris TJ, Zafar AM, Murphy TP. Utilization of lower extremity arterial disease diagnostic and revascularization procedures in medicare beneficiaries 2000-2007. AJR Am J Roentgenol. 2011 Aug;197(2):W314-7. PMID: 21785058

Dubel GJ, Ferland RJ, Murphy TP, Frishman G. The emerging role of uterine artery embolization in the management of symptomatic uterine fibroids. Med Health R I. 2000 Oct;83(10):305-11.

Merport M, Murphy TP, Egglin TK, Dubel GJ. Fibrin sheath stripping vs. catheter exchange for the treatment of failed tunneled hemodialysis catheters: randomized clinical trial. J Vasc Interv Radiol 2000;11(9):1115-20.

Semba CP, Bakal CW, Calis KA, Grubbs GE, Hunter DW, Matalon TA, Murphy TP, Stump DC, Thomas S, Warner DL. Alteplase as an alternative to urokinase. Advisory Panel on Catheter-Directed Thrombolytic Therapy. J Vasc Interv Radiol. 2000 Mar;11(3):279-87.

Semba CP, Murphy TP, Bakal CW, Calis KA, Matalon TA.Thrombolytic therapy with use of alteplase (rt-PA) in peripheral arterial occlusive disease: review of the clinical literature. The Advisory Panel. J Vasc Interv Radiol. 2000 Feb;11(2 Pt 1):149-61.

Dubel GJ, Ferland RJ, Murphy TP, Frishman G.The emerging role of uterine artery embolization in the management of symptomatic uterine fibroids. Med Health R I. 2000;83(10):305-11.

Khan N, Murphy TP, Soares GM, Zahir IS. Clinical services provided by interventional radiologists to medicare beneficiaries in the United States, 2000-2003. J Vasc Interv Radiol 2005;16(12):1753-7.

Dhangana R, Murphy TP, Pencina MJ, Zafar AM. Prevalence of low ankle-brachial index, elevated plasma fibrinogen and CRP across Framingham risk categories: Data from the National Health and Nutrition Examination Survey (NHANES) 1999-2004. Atherosclerosis. 2010 Oct 23. [Epub ahead of print] PMID: 21414621

Soares GS, Murphy TP. Transcaval TIPS: Indications and anatomic considerations. J Vasc Interv Radiol 1999;10:1233-1238.

Sheeran SR, Murphy TP, Khwaja A, Sussman SK, Hallisey MJ. Stent placement for treatment of mesenteric artery stenoses or occlusions. J Vasc Interv Radiol 1999;10:861-867.

Sheeran SR, Gestring ML, Murphy TP, Slaiby JM. Endovascular graft-related iliac artery infection. J Vasc Interv Radiol 1999;10:877-882.

Hoffman AI, Lambiase RE, Haas RA, Rogg JM, Murphy TP. Acute vertebrobasilar occlusion: Treatment with high-dose intraarterial urokinase. AJR1999;172:709-712.

Gupta H, Murphy TP, Soares GM. Use of a puncture needle for recanalization of an occluded subclavian vein. Cardiovasc Interv Radiol 1998;21(6):508-511. (Dr. Gupta is a PGY-5 resident).

Murphy TP, Webb MS. Percutaneous extravascular venous bypass for dialysis-related subclavian vein occlusion. J Vasc Interv Radiol 1998;9(6):935-939.

Murphy TP, Ahmed AI, Webb MS. Results of aortoiliac stent placement in patients treated for intermittent claudication. J Vasc Interv Radiol 1998;9:421-428.

Murphy TP, Beecham RP, Kim HM, Webb MS, Scola F. Long-term follow-up after TIPS: Use of Doppler velocity criteria for detecting elevation of the portosystemic gradient. J Vasc Interv Radiol 1998;9:275-281.

Murphy TP. Medical Outcomes Studies in peripheral vascular disease. J Vasc Interv Radiol 1998;9(6):1-11.

Murphy TP, Marks MJ, Webb MS. Use of a curved needle for true lumen re-entry during subintimal iliac artery revascularization. J Vasc Interv Radiol 1997;8:633-636.

Hoffman A, Murphy TP. Septic arteritis causing iliac artery rupture and aneurysmal transformation of the distal aorta after iliac artery stent placement. J Vasc Interv Radiol 1997;8:215-219. (Dr. Hoffman is a PGY-3 resident).

Ahmed A, Murphy TP. Spiral basket for percutaneous embolectomy of the infrageniculate popliteal artery. J Vasc Interv Radiol 1997;8:71-73. (Dr. Ahmed is a PGY-3 resident).

Sheeran SR, Hallisey MJ, Murphy TP, Faberman RS, Sherman S. Local thrombolytic therapy as part of a multidisciplinary approach to acute axillosubclavian vein thrombosis (Paget-Schroetter Syndrome). J Vasc Interv Radiol 1997;8:253-260.

Murphy TP, Soares GM, Kim HM.. Increase in utilization of percutaneous renal artery interventions by Medicare beneficiaries, 1996-2000. AJR 2004; 183(3): 561-568.

Ludwig DR, Murphy TP, Tung GA. General case of the day. RadioGraphics 1996;16:1231-1234. (Dr. Ludwig is a PGY-5 resident).

Murphy TP, Webb MS, Lambiase RE, Haas RA, Dorfman GS, Carney WI, Morin CJ. Percutaneous revascularization of complex iliac artery stenoses and occlusions using Wallstents: 3-year experience. J Vasc Interv Radiol 1996;7:21-27.

Murphy TP. Subintimal revascularization of chronic iliac artery occlusions. J Vasc Interv Radiol 1996;7:47-51.

Murphy TP, Lambiase RE, Dorfman GS, Webb MS, Haas RA, Beecham RP. Effect of spontaneous splenorenal shunts on portal hemodynamics: limited regression of varices after TIPS. J Vasc Interv Radiol 1995;6(5):700-702.

Beecham RP, Dorfman GS, Cronan JJ, Spearman MP, Murphy TP, Scola FH. Is bilateral lower extremity compression sonography useful and cost-effective in the evaluation of patients with suspected pulmonary embolism? AJR 1993;161:1289-1292.

Cronan JJ, Murphy TP. A comprehensive review of vascular ultrasound for the intensivist. J Intensive Care Med 1993;8:188-201.

Murphy TP, Dorfman GS, Becker J. Preprocedure test use by interventional radiologists. Radiology 1993;186:213-220.

Murphy TP, Dorfman GS, Esparza AR, Duwaji MS, Smith WJ. Arteriosclerosis obliterans in an animal model. Invest Radiol 1992;27:1059-1063.

Murphy TP, Dorfman GS, Segall M, Carney WI. Iatrogenic arterial dissection: treatment with percutaneous transluminal angioplasty. Cardiovasc Intervent Radiol 1991;14:302–306.

Murphy TP, Dorfman GS, Yedlicka JW, McCowan TC, Vogelzang RL, Hunter D, Carver DK, Pinsk R, Castaneda-Zuniga W, Ferris EJ, Amplatz K. The LGM vena cava filter: objective evaluation of early results. J Vasc Interv Radiol 1991;2:107–115.

Murphy TP, Cronan JJ. Evolution of deep venous thrombosis: a prospective evaluation with US. Radiology 1990;177:543–548.

Murphy TP, Cronan JJ, Paolella LP, Dorfman GS, Francis WW. Arterial rupture without balloon rupture during percutaneous transluminal angioplasty. J Vasc Surg 1987;6:528–530.

Khan N, Murphy TP, Cooper C. Renal stenting with distal protection device. Medicine and Health Rhode Island, submitted.

Murphy TP, Cooper CJ, Dworkin LD, Henrich WL, Rundback JH, Matsumoto AH, Jamerson KA, D'Agostino RB. The CORAL (Cardiovascular Outcomes with Renal Atherosclerotic Lesions) Study: Rationale and Methods. J Vasc Interv Radiol.

research overview

Dr. Murphy is currently serving as the national co-principal investigator for the Cardiovascular Outcomes with Renal Atherosclerotic Lesions (CORAL) study, the largest National Institutes of Health/National Heart, Lung and Blood Institute (NIH/NHLBI) funded multicenter randomized clinical trial examining treatment for renal artery stenosis and hypertension. He is also the national principal investigator for the largest NIH/NHLBI funded multicenter randomized clinical trial for interventional treatment of intermittent claudication (CLEVER) study.

research statement

Dr. Timothy Murphy, a professor in the Department of Diagnostic Imaging, is primarily interested in the role of percutaneous revascularization procedures in the management of people with peripheral arterial disease. Peripheral arterial disease includes atherosclerotic disease of all non-coronary arterial circulations, including the carotid, renal, and lower extremity arteries. Millions of Americans are afflicted with peripheral arterial diseases, which entail substantial morbidity and mortality and, therefore, are a major public health problem. Dr. Murphy, through the Vascular Disease Research Center, conducts multi-center National Institutes of Health (NIH) clinical trials to learn the optimal ways to manage patients with peripheral arterial diseases.

funded research

  1. Research Project #0616-02-92: "Evaluation of a Rotating Angioplasty Device in Rabbits and Swine". Burron Medical, Inc., $32,373, in 1991-1992. Co-investigator.

  2. Research Project #7481: "Intra-arterial Urokinase Therapy Utilizing a Recombinant Urokinase in the Treatment of Peripheral Arterial Thromboembolic Occlusions". Abbott Laboratories, $230,400 in 1991-1993. Co-investigator.

  3. Research Project #0074: "Recombinant Urokinase vs. Operative Intervention for Acute Lower Limb Arterial Occlusion". Abbott Laboratories, $6,345.00 in 1993-1994. Co-investigator.

  4. Research Project #7384-01-94: "Feasibility of Endovascular AAA Repair in Swine". W.L. Gore & Associates, $4,000.00 beginning in January 1994. Principal Investigator.

  5. Research Project #7669-01-95: "Possis Angiojet Rheolytic Thrombectomy System Clinical Protocol". Possis Medical, Inc., $7,650.50 for 2 years beginning June 1995. Site Principal Investigator, National Co-investigator.

  6. Research Project #96-0165: "Outcomes Study of Endovascular Stent Placement for Intermittent Claudication". Cardiovascular and Interventional Radiology Research and Education Foundation (CIRREF) grant, $10,000.00. June 1, 1996 to May 30, 1997. Principal Investigator.

  7. Continuation of Research Project #96-0165: "Outcomes Study of Endovascular Stent Placement for Intermittent Claudication". Cardiovascular and Interventional Radiology Research and Education Foundation (CIRREF) grant, $10,288.39. June 1, 1997 to May 30, 1998. Principal Investigator.

  8. Research Project #7082-01-97: "Wallgraft Endoprothesis with PET Covering and the Unistep LS Delivery System". Schneider (USA), Inc., Minneapolis, Minnesota. $43,912.84. Site Principal Investigator, National Co-investigator. June 27, 1997 to May 31, 1998.

  9. "Health Services Research in Renal Artery Revascularization Services: Utilization by Medicare Beneficiaries 1996-2000". Cardiovascular and Interventional Radiology Research and Education Foundation (CIRREF), $14,700, December 2001 through November 2002.

  10. "Prostate Embolization for Massive Benign Prostatic Hypertrophy (BPH). Phase I clinical trial". Investigator-initiated IDE by Dr. Murphy. Sponsor: Biosphere (Rockland, MA). November 2003.

  11. "A Phase II, Multicenter, Open-Label, Dose-Escalation Study to Evaluate the Safety and Activity of Alfimeprase in Patients with Acute Peripheral Arterial Occlusion". Sponsor: Nuvelo (Sunnyvale, CA). Site Investigator. November 2003. $205,406.

  12. 1 R01 HL071556-01 "The CORAL Study: Cardiovascular Outcomes with Renal Artery Lesions". Co-principal Investigator, 35% effort. National Heart, Lung, and Blood Institute, funding notification March 2004. Total award $12.9 million, subcontract $818,839.

  13. "RESIST Study (Abciximab and AngioGruar in Renal Artery Stenting)". Sponsor: Medical College of Ohio/Cordis, Inc. Chris Cooper, M.D., Principal Investigator. $46,600. November 2003.

  14. "CREST (Carotid Revascularization vs. Endarterectomy Stenting Trial)": National Institutes of Health/National Institute of Neurological Disorders and Stroke, 3/1/2005, up to $227,400 (per enrollment). Site Principal Investigator.

  15. R01 HL077221—Principal Investigator, 20% effort, "CLEVER Study (Claudication: Exercise vs. Endoluminal Revascularization)—National Heart, Lung, and Blood Institute, funding notification August 15, 2005, $5.7 million.