B.A., Reed College, 1992 (w/Patrick McDougal)
Ph.D., University of llinois at Urbana-Champaign, 1996 (w/Peter Beak)
Post-doctoral training, Princeton University 1996-1999 (w/Daniel Kahne)
| Rueda, Sebastian, McCubbin, Tyler J., Shieh, Meg, Hoshing, Raghuraj, Braun, David M., Basu, Amit. "A Functionalizable Analog of the Yariv Reagent for AGP Imaging using Fluorescence Microscopy." Bioconjugate Chemistry, vol. 34, no. 8, 2023, pp. 1398-1406. |
| Haubrich BA, Nayyab S, Gallati M, Hernandez J, Williams C, Whitman A, Zimmerman T, Li Q, Chen Y, Zhou CZ, Basu A, Reid CW. "Inhibition of Streptococcus pneumoniae growth by masarimycin." Microbiology (Reading, England), vol. 168, no. 4, 2022. |
| Muzulu J, Basu A. "Detection of ligand binding to glycopolymers using saturation transfer difference NMR." Physical Chemistry Chemical Physics, vol. 23, no. 38, 2021, pp. 21934-21940. |
| Hoshing R, Leeber B 3rd, Kuhn H, Caianiello D, Dale B, Saladino M, Lusi R, Palaychuk N, Weingarten S, Basu A. "The chirality of aggregated Yariv reagents correlates with their AGP-binding ability." ChemBioChem, 2021. |
| Hoshing R, Saladino M, Kuhn H, Caianiello D, Lusi RF, Basu A. "An Improved Protocol for the Synthesis and Purification of Yariv Reagents." J. Org. Chem., vol. 85, no. 24, 2020, pp. 16236-16242. |
| Nayyab S, O'Connor M, Brewster J, Gravier J, Jamieson M, Magno E, Miller RD, Phelan D, Roohani K, Williard P, Basu A, Reid CW. "Diamide Inhibitors of the Bacillus subtilis N-Acetylglucosaminidase LytG That Exhibit Antibacterial Activity." ACS Infectious Diseases, vol. 3, no. 6, 2017, pp. 421-427. |
| Okoth, Ronald, Basu, Amit. "Glycopolymers Prepared by Ring-Opening Metathesis Polymerization Followed by Glycoconjugation Using a Triazole-Forming “Click” Reaction." Methods in Molecular Biology, 2016, pp. 29-37. |
| Kuhn H, Gutelius D, Black E, Nadolny C, Basu A, Reid C. "Anti-bacterial glycosyl triazoles - Identification of an N-acetylglucosamine derivative with bacteriostatic activity against Bacillus." MedChemComm, vol. 5, no. 8, 2014, pp. 1213-1217. |
| Dräger, Marius, Basu, Amit. "Galactan synthesis in a single step via oligomerization of monosaccharides." Beilstein J. Org. Chem., vol. 10, 2014, pp. 2658-2663. |
| Okoth, Ronald, Basu, Amit. "End-labeled amino terminated monotelechelic glycopolymers generated by ROMP and Cu(I)-catalyzed azide–alkyne cycloaddition." Beilstein J. Org. Chem., vol. 9, 2013, pp. 608-612. |
| Zhao, Jingsha, Liu, Yuanfang, Park, Hyun-Joo, Boggs, Joan M., Basu, Amit. "Carbohydrate-Coated Fluorescent Silica Nanoparticles as Probes for the Galactose/3-Sulfogalactose Carbohydrate–Carbohydrate Interaction Using Model Systems and Cellular Binding Studies." Bioconjugate Chem., vol. 23, no. 6, 2012, pp. 1166-1173. |
| Boggs, Joan M., Gao, Wen, Zhao, Jingsha, Park, Hyun-Joo, Liu, Yuanfang, Basu, Amit. "Participation of galactosylceramide and sulfatide in glycosynapses between oligodendrocyte or myelin membranes." FEBS Letters, vol. 584, no. 9, 2010, pp. 1771-1778. |
| Wang, Yaqi, Gildersleeve, Jeffrey C., Basu, Amit, Zimmt, Matthew B. "Photo- and Biophysical Studies of Lectin-Conjugated Fluorescent Nanoparticles: Reduced Sensitivity in High Density Assays †." The Journal of Physical Chemistry B, vol. 114, no. 45, 2010, pp. 14487-14494. |
| Liu, Xiang, Basu, Amit. "Core Functionalization of Hollow Polymer Nanocapsules." J. Am. Chem. Soc., vol. 131, no. 16, 2009, pp. 5718-5719. |
| Seah, Nicole, Santacroce, Paul V., Basu, Amit. "Probing the Lactose·GM3 Carbohydrate−Carbohydrate Interaction with Glycodendrimers." Organic Letters, vol. 11, no. 3, 2009, pp. 559-562. |
| Liu, Xiang, Basu, Amit. "Cross-Linked Polynorbornene-Coated Gold Nanoparticles: Dependence of Particle Stability on Cross-Linking Position and Cross-Linker Structure." Langmuir, vol. 24, no. 19, 2008, pp. 11169-11174. |
| Limapichat, Walrati, Basu, Amit. "Reagentless functionalization of gold nanoparticles via a 3 + 2 Huisgen cycloaddition." Journal of Colloid and Interface Science, vol. 318, no. 1, 2008, pp. 140-144. |
| Park YS, Yum EK, Basu A, Beak P. "Dynamic thermodynamic resolution: solvent effects, mechanism, and an asymmetric 3,4,5-substituted benzazepine synthesis." Organic Letters, vol. 8, no. 13, 2006, pp. 2667-70. |
| BASU, A, SCHNEIDER, J. "Model systems." Current opinion in chemical biology, vol. 10, no. 6, 2006, pp. 527-528. |
| Liu, Xiang, Basu, Amit. "Olefin metathesis on nanostructures." Journal of Organometallic Chemistry, vol. 691, no. 24-25, 2006, pp. 5148-5154. |
| Fei, Jiangfeng, Basu, Amit, Xue, Fengtian, Palmore, G. Tayhas R. "Two Polymerizable Derivatives of 2,2‘-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)." Organic Letters, vol. 8, no. 1, 2006, pp. 3-6. |
| Rossi, Lauren L., Basu, Amit. "Glycosidase inhibition by 1-glycosyl-4-phenyl triazoles." Bioorganic & Medicinal Chemistry Letters, vol. 15, no. 15, 2005, pp. 3596-3599. |
| Rai, Anand Narain, Basu, Amit. "Synthesis of the Glycosphingolipid β-Galactosyl Ceramide and Analogues via Olefin Cross Metathesis." J. Org. Chem., vol. 70, no. 20, 2005, pp. 8228-8230. |
| Mulla, Hormuzd R., Agard, Nicholas J., Basu, Amit. "3-Methoxycarbonyl-5-nitrophenyl boronic acid: high affinity diol recognition at neutral pH." Bioorganic & Medicinal Chemistry Letters, vol. 14, no. 1, 2004, pp. 25-27. |
| Mulla HR, Agard NJ, Basu A. "3-Methoxycarbonyl-5-nitrophenyl boronic acid: high affinity diol recognition at neutral pH." Bioorganic & Medicinal Chemistry Letters, vol. 14, no. 1, 2004, pp. 25-7. |
| Rangin, Marianne, Basu, Amit. "Lipopolysaccharide Identification with Functionalized Polydiacetylene Liposome Sensors." J. Am. Chem. Soc., vol. 126, no. 16, 2004, pp. 5038-5039. |
| Rai, Anand Narain, Basu, Amit. "Sphingolipid Synthesis via Olefin Cross Metathesis: Preparation of a Differentially Protected Building Block and Application to the Synthesis of d - e rythro -Ceramide." Organic Letters, vol. 6, no. 17, 2004, pp. 2861-2863. |
| Santacroce, Paul V., Basu, Amit. "Studies of the carbohydrate-carbohydrate interaction between lactose and GM 3 using Langmuir monolayers and glycolipid micelles." Glycoconj J, vol. 21, no. 3/4, 2004, pp. 89-95. |
| Basu A, Kahne D. "Overcoming degeneracy in carbohydrate recognition." Angew. Chem. Int. Ed. Engl., vol. 42, no. 22, 2003, pp. 2504-6. |
| Santacroce PV, Basu A. "Probing specificity in carbohydrate-carbohydrate interactions with micelles and Langmuir monolayers." Angew. Chem. Int. Ed. Engl., vol. 42, no. 1, 2003, pp. 95-8. |
| Basu A, Thayumanavan S. "Configurational stability and transfer of stereochemical information in the reactions of enantioenriched organolithium reagents." Angew. Chem. Int. Ed. Engl., vol. 41, no. 5, 2002, pp. 717-38. |
Our group is interested in questions that lie at the interface of chemistry, biology, and materials science. Research in the group includes glycochemistry and glycobiology; synthesis and application of novel polymers and nanomaterials; development of new sensors and diagnostic agents. Current foci include the glcyochemistry of the plant cell wall and the development of small molecules that interfere with bacterial cell wall dynamics and can serve as leads for new antibiotics.
| Year | Degree | Institution |
|---|---|---|
| 1996 | PhD | University of Illinois at Urbana-Champaign |
| 1992 | BA | Reed College |
RC Fuson Research Award, 1995
Department of Education/Chevron Graduate Fellowship, 1994-1995
Research Innovation Award, 2001-2006
National Science Foundation (NSF) Faculty Early CAREER Award, 2002-2006
Mizutani Award in Glycoscience 2005
Karen T Romer Advising Prize 2014
| CHEM 0360 - Organic Chemistry |
| CHEM 0360 - Organic Chemistry II |
| CHEM 0910 - The Language of Chemistry |
| CHEM 1450 - Advanced Organic Chemistry |
| CHEM 2410 - Organic Mechanisms |
| CHEM 2410 - Physical Organic Chemistry |
| CHEM 2420 - Organic Reactions |
| CHEM 2430 - Synthetic Organic Chemistry |
