Dr. Morrison is a graduate of both the University of Massachusetts at Amherst and the University of Massachusetts Medical School, where he obtained an M.D. and a Ph.D. in Biomedical Sciences. He completed internship and residency in Medicine at Yale University School of Medicine and Yale New Haven Hospital. He remainded at Yale for Cardiovascular Medicine Fellowship and postdoctoral research training in vascular biology. Dr. Morrison is board certified in Medicine, Cardiology, and Advanced Cardiovascular Imaging in the area of Nuclear Cardiology and Cardiac CT. Dr. Morrison was first appointed to Assistant Professor of Medicine at the Warren Alpert Medical School of Brown University in 2016 and was promoted to Associate Professor of Medicine in 2022.
Dr. Morrison has combined careers in clinical cardiovascular medicine, teaching, and vascular biology research. He maintains a strong interest in developing basic research projects that have translational impact for clinical disease. His research laboratory focuses on immune-mediate vascular remodeling by studying macrophage-directed processes influencing angio/arteriogenesis, atherosclerosis and vascular calcification, aortic valve disease, and pulmonary hypertension. His clinical research interests involve cardiac imaging, epidemiology, and outcomes.
| Ngamdu KS, Ghosalkar DS, Chung HE, Christensen JL, Lee C, Butler CA, Ho T, Chu A, Heath JR, Baig M, Wu WC, Choudhary G, Morrison AR. "Long-term statin therapy is associated with severe coronary artery calcification." PLoS ONE, vol. 18, no. 7, 2023, pp. e0289111. |
| Sharma S, Morrison AR. "Unlocking the Secrets of Subclinical Calcific Aortic Valve Disease and Heart Failure." Circulation. Cardiovascular imaging, vol. 16, no. 3, 2023, pp. e015247. |
| Sumayin Ngamdu K, Mallawaarachchi I, Dunipace EA, Chuang LH, Jafri SH, Shah NR, Jeong YN, Morrison AR, Bhatt DL. "Association Between Periodontal Disease and Cardiovascular Disease (from the NHANES)." The American Journal of Cardiology, vol. 178, 2022, pp. 163-168. |
| Mantsounga CS, Lee C, Neverson J, Sharma S, Healy A, Berus JM, Parry C, Ceneri NM, López-Giráldez F, Chun HJ, Lu Q, Sellke F, Choudhary G, Morrison AR. "Macrophage IL-1β promotes arteriogenesis by autocrine STAT3- and NF-κB-mediated transcription of pro-angiogenic VEGF-A." Cell Reports, vol. 38, no. 5, 2022, pp. 110309. |
| Chung HE, Chen J, Ghosalkar D, Christensen JL, Chu AJ, Mantsounga CS, Neverson J, Soares C, Shah NR, Wu WC, Choudhary G, Morrison AR. "Aortic Valve Calcification Is Associated with Future Cognitive Impairment." Journal of Alzheimer's Disease Reports, vol. 5, no. 1, 2021, pp. 337-343. |
| Soares C, Samara A, Yuyun MF, Echouffo-Tcheugui JB, Masri A, Samara A, Morrison AR, Lin N, Wu WC, Erqou S. "Coronary Artery Calcification and Plaque Characteristics in People Living With HIV: A Systematic Review and Meta-Analysis." Journal of the American Heart Association, vol. 10, no. 19, 2021, pp. e019291. |
| Shah NR, Eisman AS, Winchester DE, Morrison AR, Qureshi R, Sarkar IN, Wu WC. "E-Consult Protocoling to Improve the Quality of Cardiac Stress Tests." JACC: Cardiovascular Imaging, vol. 14, no. 2, 2021, pp. 512-514. |
| Lee, Cadence F., Carley, Rachel E., Butler, Celia A., Morrison, Alan R. "Rac GTPase Signaling in Immune-Mediated Mechanisms of Atherosclerosis." Cells, vol. 10, no. 11, 2021, pp. 2808. |
| Vang A, da Silva Gonçalves Bos D, Fernandez-Nicolas A, Zhang P, Morrison AR, Mancini TJ, Clements RT, Polina I, Cypress MW, Jhun BS, Hawrot E, Mende U, O-Uchi J, Choudhary G. "⍺7 nicotinic acetylcholine receptor mediates right ventricular fibrosis and diastolic dysfunction in pulmonary hypertension." JCI insight, vol. 6, no. 12, 2021. |
| Christensen JL, Tan S, Chung HE, Ghosalkar DS, Qureshi R, Chu A, Yu W, Berus J, Shah NR, Wu WC, Chun H, Aikawa E, Choudhary G, Morrison AR. "Aortic valve calcification predicts all-cause mortality independent of coronary calcification and severe stenosis." Atherosclerosis, vol. 307, 2020, pp. 16-20. |
| Lakshmanan, Suvasini, Jankowich, Matthew, Wu, Wen-Chih, Abbasi, Siddique, Morrison, Alan R, Choudhary, Gaurav. "Association of plasma adiponectin with pulmonary hypertension, mortality and heart failure in African Americans: Jackson Heart Study." Pulmonary Circulation, vol. 10, no. 4, 2020, pp. 204589402096124. |
| Ahmad, Khansa, Erqou, Sebhat, Shah, Nishant, Nazir, Umair, Morrison, Alan R., Choudhary, Gaurav, Wu, Wen-Chih. "Association of poor housing conditions with COVID-19 incidence and mortality across US counties." PLOS ONE, vol. 15, no. 11, 2020, pp. e0241327. |
| Christensen, Jared L., Yu, Wenzheng, Tan, Sydney, Chu, Alice, Vargas, Fabian, Assali, Maen, Shah, Nishant R., Reginato, Anthony M., Wu, Wen-Chih, Choudhary, Gaurav, Morrison, Alan R. "Gout Is Associated With Increased Coronary Artery Calcification and Adverse Cardiovascular Outcomes." JACC: Cardiovascular Imaging, vol. 13, no. 3, 2020, pp. 884-886. |
| Healy A, Berus JM, Christensen JL, Lee C, Mantsounga C, Dong W, Watts JP Jr, Assali M, Ceneri N, Nilson R, Neverson J, Wu WC, Choudhary G, Morrison AR. "Statins Disrupt Macrophage Rac1 Regulation Leading to Increased Atherosclerotic Plaque Calcification." Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 40, no. 3, 2020, pp. 714-732. |
| Mantsounga, Chris Sorel, Morrison, Alan R. "Empagliflozin and Protecting Microvascular Support of Heart Mechanics." JACC: Basic to Translational Science, vol. 4, no. 5, 2019, pp. 592-595. |
| Imran HM, Baig M, Erqou S, Taveira TH, Shah NR, Morrison A, Choudhary G, Wu WC. "Home-Based Cardiac Rehabilitation Alone and Hybrid With Center-Based Cardiac Rehabilitation in Heart Failure: A Systematic Review and Meta-Analysis." Journal of the American Heart Association, vol. 8, no. 16, 2019, pp. e012779. |
| Christensen JL, Sharma E, Gorvitovskaia AY, Watts JP Jr, Assali M, Neverson J, Wu WC, Choudhary G, Morrison AR. "Impact of Slice Thickness on the Predictive Value of Lung Cancer Screening Computed Tomography in the Evaluation of Coronary Artery Calcification." Journal of the American Heart Association, vol. 8, no. 1, 2019, pp. e010110. |
| Clements RT, Vang A, Fernandez-Nicolas A, Kue NR, Mancini TJ, Morrison AR, Mallem K, McCullough DJ, Choudhary G. "Treatment of Pulmonary Hypertension With Angiotensin II Receptor Blocker and Neprilysin Inhibitor Sacubitril/Valsartan." Circulation: Heart Failure, vol. 12, no. 11, 2019, pp. e005819. |
| Shah, Nishant R., Blankstein, Ron, Villines, Todd, Imran, Hafiz, Morrison, Alan R., Cheezum, Michael K. "Coronary CTA for Surveillance of Cardiac Allograft Vasculopathy." Current Cardiovascular Imaging Reports, vol. 11, no. 11, 2018, pp. 26. |
| Hwangbo C, Wu J, Papangeli I, Adachi T, Sharma B, Park S, Zhao L, Ju H, Go GW, Cui G, Inayathullah M, Job JK, Rajadas J, Kwei SL, Li MO, Morrison AR, Quertermous T, Mani A, Red-Horse K, Chun HJ. "Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects." Science Translational Medicine, vol. 9, no. 407, 2017. |
| Ceneri N, Zhao L, Young BD, Healy A, Coskun S, Vasavada H, Yarovinsky TO, Ike K, Pardi R, Qin L, Qin L, Tellides G, Hirschi K, Meadows J, Soufer R, Chun HJ, Sadeghi MM, Bender JR, Morrison AR. "Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production." Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 37, no. 2, 2017, pp. 328-340. |
| Bailey G, Healy A, Young BD, Sharma E, Meadows J, Chun HJ, Wu WC, Choudhary G, Morrison AR. "Relative predictive value of lung cancer screening CT versus myocardial perfusion attenuation correction CT in the evaluation of coronary calcium." PLOS ONE, vol. 12, no. 4, 2017, pp. e0175678. |
| Bailey G, Meadows J, Morrison AR. "Imaging Atherosclerotic Plaque Calcification: Translating Biology." Current Atherosclerosis Reports, vol. 18, no. 8, 2016, pp. 51. |
| Morrison AR, Yarovinsky TO, Young BD, Moraes F, Ross TD, Ceneri N, Zhang J, Zhuang ZW, Sinusas AJ, Pardi R, Schwartz MA, Simons M, Bender JR. "Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis." Journal of Experimental Medicine, vol. 211, no. 10, 2014, pp. 1957-68. |
| Morrison AR, Sinusas AJ. "Advances in radionuclide molecular imaging in myocardial biology." Journal of Nuclear Cardiology, vol. 17, no. 1, 2010, pp. 116-34. |
| Morrison AR, Sinusas AJ. "New molecular imaging targets to characterize myocardial biology." Cardiology clinics, vol. 27, no. 2, 2009, pp. 329-44, Table of Contents. |
| Heysell SK, Thomas TA, Morrison AR, Barry M. "Salmonella panama and acute respiratory distress syndrome in a traveler taking a proton pump inhibitor." Journal of Travel Medicine, vol. 15, no. 6, 2008, pp. 460-3. |
| Morrison AR, Moss J, Stevens LA, Evans JE, Farrell C, Merithew E, Lambright DG, Greiner DL, Mordes JP, Rossini AA, Bortell R. "ART2, a T cell surface mono-ADP-ribosyltransferase, generates extracellular poly(ADP-ribose)." Journal of Biological Chemistry, vol. 281, no. 44, 2006, pp. 33363-72. |
| Zheng X, Morrison AR, Chung AS, Moss J, Bortell R. "Substrate specificity of soluble and membrane-associated ADP-ribosyltransferase ART2.1." Journal of cellular biochemistry, vol. 98, no. 4, 2006, pp. 851-60. |
| Year | Degree | Institution |
|---|---|---|
| 2005 | PhD | University of Massachusetts Medical School |
| 2005 | MD | University of Massachusetts Medical School |
| 1996 | BS | University of Massachusetts, Amherst |
2023 Brown University Early Career Research Achievement Award
2023 Honorary Degree conferred during Brown University at 255th Commencement: Master of Arts ad eundem
2022 Brown Outstanding Achievement for a Master’s Degree Award (Cadence Lee, mentee)
2022 Emerging Scientist Award for Women 2022 Winner, given by Women’s Leadership Committee of the American Heart Association’s Council on Arteriosclerosis, Thrombosis, and Vascular Biology (Cadence Lee, mentee)
2021 Harold S. Geneen Charitable Trust Award Program for Coronary Heart Disease Research
2017 Presidential Early Career Award for Scientists and Engineers, Nominee 2017
2016 Best Abstract, Providence VA Medical Center, VA National Research Day, 05/2016.
2015 Actelion ENTELLIGENCE Young Investigator Award, 08/2015
2013 Third Place Junior Faculty Award for Basic Science: Northwestern Cardiovascular Young Investigators' Forum, Northwestern University Feinberg School of Medicine, 9/2013.
2013 Invited Abstract Finalist: Northwestern Cardiovascular Young Investigators' Forum, Northwestern University Feinberg School of Medicine, 7/2013.
2012 NIH Loan Repayment Program Award, 7/2012.
2012 ATVB Travel Award for Young Investigators, 4/2012.
2009 NIH Individual Ruth L. Kirschstein National Research Service Award (NRSA), 7/2009.
