Christian Parcher NixonAssistant Professor of Pathology and Laboratory Medicine
Expertise/Certifications: Transfusion Medicine, International Health Research
Office number: 401-444-7375
(Lab Customer Service: 401-793-4242)
Christian Nixon received his MD/PhD from Brown University in 2008. He completed residencies in clinical and anatomic pathology at University of California at San Francisco and Yale Medical School respectively, and a blood bank fellowship in the Joint Program in Transfusion Medicine at Harvard Medical School. After completing residency/fellowship in 2014, he joined the faculty at Brown University in the Department of Pathology and Laboratory Medicine and serves as an attending physician on the Transfusion Medicine and Coagulation Service at Rhode Island Hospital.
The Nixon laboratory investigates the immuno-epidemiology of malaria as a tool to inform malaria vaccine design and development, as well as the functional significance of antibody targeted cellular and complement responses to a novel pediatric malaria vaccine candidate identified here at Brown. Additional interests include the application of modern geographical information systems to the identification and stratification of risk factors for malaria in hypo- to mesoendemic areas such as that typified by eastern Indonesia.
We focus on the functional significance of antibody targeted cellular and complement responses to a novel pediatric malaria vaccine candidate that was discovered here at Brown in the Center for International Health Research. Elucidating the roles of cellular effector mechanisms to this vaccine target will help to guide ongoing immune-epidemiology studies and ultimately vaccine trials. As a second aim, the Nixon Laboratory will focus on identifying novel vaccine targets against the transmissible form of the malaria parasite, the gametocyte, while it still resides within the human host. Novel vaccine candidates that target this stage will ultimately be incorporated into a multi-stage vaccine that target the liver and blood stage of malaria.