1) Smoking among alcoholics and substance abusers: interactions and treatment

2) New pharmacotherapies and tobacco products for tobacco or alcohol dependence

3) Implementing medication treatment for opioid use disorder in justice settings

4) Culturally adapting interventions to immigration/discrimination stress for Latinx.

5) Cue exposure, coping skills treatment, motivational enhancement and other new behavioral treatments for alcoholism or cocaine abuse

6) Effects of hangover on performance in simulators

7) Cognitive mediators of outcome in alcohol and cocaine abuse

8) Development of new assessment tools for alcohol, nicotine and cocaine dependence

Overview of Current Research Projects
Damaris J. Rohsenow, Ph.D.  

(7-2020)

            My current and recent research program has focused on social learning theory oriented approaches to the etiology and treatment of alcoholism, cocaine abuse and smoking, on the development of behavioral and pharmacologic treatment approaches, and on determinants and effects of nonalcoholic drinking.

Medicated assisted treatment for opioid use disorder in the justice system

            My primary current research focus is co-leading a hybrid type 1 implementation-effectiveness study designed to implement medication-assisted treatment for opioid disorder in seven probation and parole sited in three states. The study will follow state-of-the-art procedures to engage community justice and treatment agencies in implementing such treatment. In the second stage, we will investigate the added value of peer-assisted counseling in a randomized controlled design. This is part of a national effort to improve services for people with opioid use disorders in the criminal justice system. 

Smoking interventions for smokers with substance use disorders. 

             Because smokers with substance use disorders smoke at an exceptionally high rate and are resistant to quitting, I have been conducting research on this topic since the early 1990’s. I recently compared very low nicotine cigarettes to normal nicotine cigarettes for biomarkers of toxicity and effects on smoking for smokers with substance use disorders.  This study will help determine how viable and safe this approach to smoking cessation is among this group of smokers. I conducted a series of studies investigating the role of smoking in risk for relapse for alcoholics before starting a series of treatment trials.  I completed a smoking treatment trial for alcoholics in state funded alcohol treatment in which brief motivational intervention was compared to brief advice to quit smoking, started in their first two weeks of treatment, showing that brief advice worked better for those with more drug use.  A second treatment trial for substance abusers in an inner-city residential substance abuse treatment program compared motivational interviewing to brief advice to quit smoking (three sessions of each) crossed with contingent vouchers (for monetary rewards) for providing breath samples showing abstinence from smoking as compared to a control procedure, and showed more abstinence after contingent vouchers.  Next I studied the effects of comparing contingency vouchers for smoking cessation to a control procedure when added to nicotine patch and counseling. Fourth, I investigated the benefits of varenicline vs. nicotine patch for smokers with substance use disorders.  The results are able to guide clinical approaches to treating this population.

Culturally adapting alcohol interventions for Latinx heavy drinkers

            Since 2005 I have collaborated with Dr. Christina Lee in studies investigating the role of discrimination and immigration stress on heavy drinking, and then on culturally adapting brief interventions (CAMI) for heavy drinking to help drinkers understand and cope with these sources of stress. Results show reduced alcohol problems and improved mental health. Currently we are starting an implementation trial to disseminate CAMI into community agencies. A measure of drinking in response to acculturation stress was developed and validated.

Past projects include investigations of pharmacotherapies or behavioral therapies for smoking, alcohol dependence, or cocaine dependence.

            Laboratory investigations of medications for smoking. I have used laboratory procedures to investigate promising new medication approaches for smoking cessation.

   1) A pilot study that showed that naltrexone combined with nicotine replacement significantly reduced smoking cue-elicited urge to smoke and withdrawal relative to nicotine replacement alone. 

  2) A larger trial of naltrexone (50 mg. vs. placebo) and nicotine replacement (0, 21 mg, 42 mg) showed little beneficial effect of combining naltrexone with transdermal nicotine overall, and showed that transdermal nicotine only reduces urges to smoke at the 42 mg dose, not the usually recommended 21 mg dose.

  3)  A third trial found significant effects of a dopamine antagonist (olanzapine) on smoking urge and withdrawal at the low dose (2.5 mg) but not the high dose (5.0 mg). 

  4) A fourth project investigated baclofen, a GABAergic medication, for effects on urge, withdrawal, and reinforcement from smoking.

            Laboratory investigations relevant to alcohol use disorder.

1) Currently I am co-investigator on a contract from NIAAA to conduct human laboratory screening program studies of medications for alcohol use disorders.

 2)  I recently collaborated on a study that uses machine-learning to build an app that will allow a user to know when they are probably too impaired to drive based on their gait.

3) I completed two studies that a single dose or two weeks of dosing with naltrexone significantly reduced urge to drink and self-reported attention to the cues in the presence of alcohol cues, but not in response to juice or water cues, indicating that naltrexone’s effect is not mediated by effects on appetite in general.  

 4) I completed a pair of laboratory studies of high doses naltrexone crossed with ondansetron for effects on reactions of alcoholics to the presence of alcohol cues and of the subjective effects of drinking alcohol by problem drinkers who have not sought treatment.

  These laboratory investigations provide a cost-efficient way to provide preliminary evidence for or against new pharmacologic agents, and to investigate hypothesized mediating mechanisms of effect. Analyses are done, writing is needed.

            Caffeine’s effects with alcohol. I was co-Principal Investigator on studies of the acute and residual effects of caffeinated beer on driving performance and sleep disruption.  Our most recent studies showed that caffeinated beer does not improve performance in driving while at .12 g% or the next morning compared to usual beer and to placebo beer, but also did not impair sleep in these healthy young adults. Working with a past post-doctoral fellow, we showed that frequency of caffeinated alcohol beverages is associated with greater alcohol misuse even when controlling for gender and the greater impulsivity in these drinkers.

            Cocaine treatment and assessment studies.  With cocaine abusers, I developed a coping skills training package that resulted in significantly fewer cocaine use days during the first 6 months of follow up.  I conducted another treatment trial in which motivational enhancement procedures were added to the coping skills training to determine the increased effectiveness of the combined approaches.  Third, I completed a study to investigate the extent to which urges to use cocaine predict cocaine use during follow up in a multivariate analysis including other pretreatment predictors.  This study also compared the relative effectiveness and predictive power of various different methods of assessing urge to use cocaine during treatment and the effectiveness of various coping strategies.  In this program of research, numerous new assessment instruments have been developed psychometrically and have been published.  The skills treatment was selected by NIDA for their library of evidence-based treatments. Considerable data are still to be mined and analyzed.

            Alcohol treatment trials.  I conducted several treatment studies with alcoholics. 1)  Cue exposure treatment and communication skills training resulted in lower relapse rates and longer latency to the first drink than did any other combination of treatments. 2)  We combined the cue exposure and communication skills training package with naltrexone versus placebo and evaluated the effects on treatment outcome.  Naltrexone reduced drinking quantity only during the 12 weeks of medication, and only among those who took at least 70% of the medication.  The behavioral treatment resulted in significantly less drinking that the control group during both the 6 and 12 month follow ups, showing lasting beneficial effects at low cost (5 sessions). 3) Secondary analyses demonstrated predictors of treatment compliance and that medication effects were limited to people with high density of family history or who were more psychopathic.  Certain urge-specific coping skills during follow-up were associated with better outcomes, and others were ineffective.  

            Several more recent studies of hangover.  1) We took people who drank to .12 g% breath alcohol in our lab and studied their transition out of drinking problems 1-3 years later.  Drinkers who reported more hangover after a standard dose of alcohol had fewer drinking problems after college, indicating a protective effect of sensitivity to hangover. 2) We showed that smoking while drinking heavily results in greater incidence and severity of hangover the next morning.

Grants of which I am PI or Multiple-PI:

 U01 DA050442-01 (Martin, Brinkley-Rubenstein, Rohsenow)    8/1/19 – 4/30/24      Role: MPI

      Using Implementation Interventions and Peer Recovery Support to Improve Opioid Treatment Outcomes in Community Supervision

      Aim: Evaluate a systems change approach to increasing linkage to medications for opioid abuse in seven probation and parole sites of opioid users in the criminal justice system, and investigate effects of adding peer support in a randomized trial.

 1R01DA034628-01A1 (Rohsenow) from NIDA             9/15/13-5/31/20 (in NCE)                                 Role: PI          

      Very Low-Nicotine Cigarettes in Smokers with SUD: Smoking, Substance Use Effects

      Aim:  Determine the effects of very-low nicotine cigarettes on safety, smoking and substance use in smokers with substance use disorder.

2T32 DA016184-06 (Rohsenow)  from NIDA              07/01/2008 - 06/30/2023                     Role: PI          

      Substance Abuse Intervention Outcome Research Training

      Aim: Train postdoctoral fellows in the conduct of intervention research.

2000-2020:  (Asterisk indicate co-authors who were mentored)

*Meshesha, L. Z., Solti, K., Wise, E. A., Rohsenow, D. J., Witkiewitz, K., & Murphy, J. G. (2020). Pilot trial investigating a brief behavioral economic intervention as an adjunctive treatment for alcohol use disorder. Journal of Substance Abuse Treatment, 113. In press doi:10.1016/j.jsat.2020.108002

Lee, C.S., *Rosales, R., Colby, S.M., Martin, R., Cox, K., & Rohsenow, D. J. (2020). Addressing social stressors in a brief motivational intervention improves mental health symptoms for Latinx heavy drinkers. Journal of Clinical Psychology. Advance on-line publication: 29 May 2020 doi.org/10.1002/jclp.22976.

Stein, L. A. R., Martin, R. A., Clair-Michaud, M., Lebeau, R., Hurlbut, W., Kahler, C. W., Monti, P. M., & Rohsenow, D. J. (2019). A randomized clinical trial of motivational interviewing plus skills training versus relaxation plus education and 12-steps for substance using incarcerated youth: Effects on alcohol, marijuana and crimes of aggression. Drug and Alcohol Dependence, 207. Advance on-line publication Dec. 13, 2019, doi.org/10.1016/j.drugalcdep.2019.107774.

*González-Roz, A., Jackson, J., *Murphy, C., Rohsenow, D. J., & MacKillop, J. (2019). Behavioral economic tobacco demand in relation to cigarette consumption and nicotine dependence: A meta-analysis of cross-sectional relationships. Addiction, 114, 1926-1940.  doi.org/10.1111/add.14736

*Murphy, C. M., *Cassidy, R. N., Martin, R. A., Tidey, J. W., MacKillop, J., & Rohsenow, D. J. (2019). Brief assessment of cigarette demand (BACD): Initial development and correlational results in adults and adolescents.  Experimental and Clinical Psychopharmacology. Advance on-line publication, Mar 21, 2019. doi: 10.1037/pha0000267

Martin, R. A., Rohsenow, D. J., & Tidey, J. W. (2019). Smokers with opioid use disorder may have worse drug use outcomes after varenicline than nicotine replacement. Journal of Substance Abuse Treatment, 104, 22-27.  doi.org/10.1016/j.jsat.2019.06.005

Lee, C.S., Colby, S.M., Rohsenow, D.J., Martin, R., *Rosales, R., Tavares-McCallum, T., Falcon, L., Almeida, J., Cortés, D.E. (2019). A randomized controlled trial of motivational interviewing tailored for heavy drinking Latinxs. Journal of Consulting and Clinical Psychology, 87, 815-830.

*Murphy, C. M., Rohsenow, D. J., Johnson, K. C., & Wing, R. R. (2018). Smoking and weight loss among overweight and obese smokers in Look Ahead. Health Psychology, 37, 399-406. doi:10.1037/hea0000607

Rohsenow, D. J, Tidey, J. W., Martin, R. A., Colby, S. M., & Eissenberg, T. (2018). Effects of six week of electronic cigarette use on smoking rate, CO, cigarette dependence, and motivation to quit smoking: A pilot study. Addictive Behaviors, 80, 65-70. DOI: 10.1016/j.addbeh.2018.01.012

*Cassidy, R. N., Jackson, K. M., Rohsenow, D. J., Tidey, J. W., Tevyaw, T. O., Barnett, N. P., Monti, P. M., *Miller, M. E., Colby, S. M. (2018). Contingency management for college student smokers: The role of drinking as a moderator and mediator of smoking abstinence during treatment. Addictive Behaviors, 80, 95-101. DOI: 10.1016/j.addbeh.2018.01.017

*Murphy, S.M., Martin, R.M., Tidey, J. W., Colby, S. M., & Rohsenow, D.J. (2018). Smoking outcome expectancies predict smoking during voucher-based treatment for smokers with substance use disorders.  Journal of Substance Abuse Treatment, 90, 73-78.

*Miller, M. E., Tidey, J. W., Rohsenow, D. J., & Higgins, S.T. (2017).  Electronic cigarette expectancies in smokers with psychological distress. Tobacco Regulatory Science, 3(1), 109-114. DOI: https://doi.org/10.18001/TRS.3.1.11  

*Murphy, C. M., MacKillop, J., Martin, R. A., Tidey, J. W., Colby, S. M. & Rohsenow, D.J.  (2017). Effects of varenicline versus transdermal nicotine replacement therapy on cigarette demand on quit day in individuals with substance use disorders. Psychopharmacology, 234, 2443-2452. DOI: 10.1007/s00213-017-4635-4

Rohsenow, D. J., Tidey, J. W., Martin, R. A., Colby, S. M., Swift, R. M., Leggio, L., & Monti, P. M. (2017). Varenicline versus nicotine patch with brief advice for smokers with substance use disorders with or without depression: Effects on smoking, substance use and depressive symptoms.  Addiction, 112, 1808-1820.  DOI: https://doi.org/ 10.1111/add.13861.

Rohsenow, D. J., Martin, R. A., Tidey, J. W., Colby, S. M., & Monti, P. M. (2017). Treating smokers in substance treatment with contingent vouchers, nicotine replacement and brief advice adapted for sobriety settings. Journal of Substance Abuse Treatment, 72, 72-79. DOI: http://dx.doi.org/10.1016/j.jsat.2016.08.012

Miranda, R., Jr., MacKillop, J., *Treloar, H., Blanchard, A., Tidey, J. W., Swift, R. M., Chun, T., Rohsenow, D. J., & Monti, P. M. (2016). Biobehavioral mechanisms of topiramate’s effects on alcohol use: An investigation pairing laboratory and ecological momentary assessments. Addiction Biology, 21, 171-182. doi: 10.1111/adb.12192

*Lechner, W. V., Knopik, V. S., McGeary, J. E., Spillane, N. S., Tidey, J. W., McKee, S. A., Metrik, J., Leventhal, A. N., Rohsenow, D. J., & Kahler, C. W. (2016).  Influence of the A118G polymorphism of the OPRM1 gene and exon 3 VNTR polymorphism of the DRD4 gene on cigarette craving after alcohol administration. Nicotine and Tobacco Research, 18, 632-636.  doi: 10.1093/ntr/ntv136

MacKillop, J., *Murphy, C. M., Martin, R. A., *Stojek, M., Tidey, J. W., Colby, S. M., & Rohsenow, D. J.  (2016). Predictive validity of a cigarette purchase task in a randomized controlled trial of contingent vouchers for smoking in individuals with substance use disorders. Nicotine and Tobacco Research, 18, 531-537.  doi: 10.1093/ntr/ntv233

Lee, C. S., Almeida, J., Colby, S. M., Tavares, T., & Rohsenow, D. J. (2016).  Acculturation, hazardous drinking and depressive symptomatology among Hispanics enrolled in a clinical trial. Addiction Research & Theory, 24(1), 69-79. DOI: 10.3109/16066359.2015.1072517

Martin RA, *Cassidy R, Murphy CM, Rohsenow DJ. (2016). Barriers to quitting smoking among substance dependent patients predict outcome. Journal of Substance Abuse Treatment, 64, 7-12. doi: 10.1016/j.jsat.2016.02.007

Metrik, J., *Aston, E. R., Kahler, C.W., Rohsenow, D. J., McGeary, J. E., Knopik, V. S., & MacKillop, J. (2016). Cue-elicited increases in incentive salience for marijuana: Craving, demand, and attentional bias.  Drug and Alcohol Dependence,167, 82-88. doi.org/10.1016/j.drugalcdep.2016.07.027

Lee, C. S., Colby, S. M., Magill, M., Almeida, J., Tavares, T., & Rohsenow, D. J. (2016). A randomized controlled trial of culturally adapted motivational interviewing for Hispanic heavy drinkers: Theory of adaptation and study protocol. Contemporary Clinical Trials, 50, 193-200. doi: 10.1016/j.cct.2016.08.013  

Martin, R. A., Stein, L. A. R., Clair, M., Cancilliere, M. K., Hurlbut, W., & Rohsenow, D.J. (2015).  Adolescent substance treatment engagement questionnaire for incarcerated teens. Journal of Substance Abuse Treatment, 57, 49-56. doi:10.1016/j.jsat.2015.04.011

Metrik, J., *Aston, E. R., Kahler, C. W., Rohsenow, D. J., McGeary, J. E., & Knopik, V. S. (2015). Marijuana’s acute effects on cognitive bias for affective and marijuana cues. Experimental and Clinical Psychopharmacology, 23, 339-350. doi: 10.1037/pha0000030. PMC4578985

Huntley, G., *Treloar, H., Blanchard, A., Monti, P. M., Carey, K. B., Rohsenow, D. J., & Miranda, R., Jr. (2015). An event-level investigation of hangovers’ relationship to age and drinking.  Experimental and Clinical Psychopharmacology, 23, 314-323. doi: 10.1037/pha0000037

*Day, A. M., Kahler, C. W., Metrik, J., Spillane, N. S., Tidey, J. W., & Rohsenow, D. J. (2015). Working memory moderates association of smoking urge and smoking behavior in a laboratory analogue task.  Nicotine and Tobacco Research, 17(9), 1173-1177. doi:10.1093/ntr/ntu259  [E-pub ahead of print 24 December 2014.]

Rohsenow, D. J., Tidey, J. W., Kahler, C. W., Martin, R. A., Colby, S. M., & Sirota, A. D. (2015). Intolerance for withdrawal discomfort and motivation predict voucher-based smoking treatment outcomes for smokers with substance use disorders. Addictive Behaviors, 43, 18-24. doi:10.1016/j.addbeh.2014.12.003.

Rohsenow, D. J., Tidey, J. W., Martin, R. A., Colby, S. M., Sirota, A. D., Swift, R. M., & Monti, P. M. (2015). Contingent vouchers and motivational interviewing for cigarette smokers in residential substance abuse treatment. Journal of Substance Abuse Treatment, 55, 29-38.  doi: 10.1016/j.jsat.2015.02.010.

Martin, R. A., *Ellingsen, V. J., *Tzilos, G. K., & Rohsenow, D. J. (2015).  General and religious coping predict drinking outcomes for alcohol dependent adults in treatment. The American Journal on Addictions, 24(3), 240-245. doi: 10.1111/ajad.12181

Monti, P. M., Colby, S. M., *Mastroleo, N. R., Barnett, N. P., Gwaltney, C. J., Apodaca, T. R., Rohsenow, D. J., Magill, M., Gogineni,  A., Mello, M. J.,  Biffl, W., & Cioffi, W. (2014). Individual versus significant other-enhanced brief motivational intervention for alcohol in emergency care. Journal of Consulting and Clinical Psychology, 82, 936-948.  doi: 10.1037/a0037658

Stein, L.A.R., Clair, M., Martin, R.A., Soenksen, S., Lebeau, R., Rohsenow, D.J., Kahler, C.W., Hurlbut, W., & Monti, P.M. (2014). Measuring behaviors of individual adolescents during group-based substance abuse intervention substance abuse. Substance Abuse, 35, 408-417. doi: 10.1080/08897077.2014.949337.   

Kahler CW, Metrik J, Spillane NS, *Day AM, Leventhal, AM, McKee SA, Tidey JW, McGeary  E, Knopik VS, Rohsenow DJ. (2014). Acute effects of low and high dose alcohol on smoking lapse behavior in a laboratory analogue task.  Psychopharmacology. Published online May 25, 2014. DOI 10.1007/s00213-014-3613-3

*Day AM, Kahler CW, Spillane NS, Metrik J, Rohsenow DJ. (2014). Length of smoking deprivation moderates the effects of alcohol administration on urge to smoke. Addictive Behaviors, 39, 976-979. doi.org/10.1016/j.addbeh.2014.01.023

Rohsenow DJ, Martin RA, Monti PM, Colby SM, *Day, AM, Abrams DB, Sirota AD, Swift RM. (2014). Motivational interviewing versus brief advice for cigarette smokers in residential alcohol treatment.  J Subst Abuse Treat 46: 346-355. PMC3947086.

Rohsenow DJ, Howland J, Alvarez L, Nelson K, Langlois B, Verster JC, Sherrard H, Arnedt JT. (2014). Effects of caffeinated vs. non-caffeinated alcoholic beverage on next-day hangover incidence and severity, perceived sleep quality, and alertness.  Addict Behav 39: 329-332. PMC3864634.  

*Amlung M, Few LR, Howland J, Rohsenow DJ, Metrik J, MacKillop J. (2013). Impulsivity and alcohol demand in relation to combined alcohol and caffeine use. Exp Clin Psychopharm 21: 467-474.  doi: 10.1037/a0034214  PMC in progress.

*Lee CS, López SR, Colby SM, Rohsenow DJ,, Hernández L, Borelli B, Caetano R. (2013). Culturally adapted motivational interviewing for Latino heavy drinkers: Results from a randomized clinical trial. J Ethn Subst Abuse, 12, 356-373. PMC3976969.

*Lee CS, Colby SM, Rohsenow DJ, López SR, Hernández L, Caetano R. (2013).  Acculturation stress and drinking problems among urban heavy drinking Latinos in the northeast. J Ethn Subst Abuse, 12, 308-320. PMC3976985.

Rohsenow DJ, Martin RA, Tidey JW, Monti PM, Colby SM. (2013).  Comparison of the Cigarette Dependence Scale with four other measures of nicotine involvement: correlations with smoking history and smoking treatment outcome in smokers with substance use disorders. Addict Behav 38: 2409-2413. doi: 10.1016/j.addbeh.2013.03.019 PMC3705939.

Howland J, Rohsenow DJ.  (2013). Risks of energy drinks mixed with alcohol.  J Amer Medical Assoc 309:245-246.  PMC3038341  

Sirota AD, Rohsenow DJ, *Dolan SL, Martin RA, Kahler CW. (2013). Intolerance for discomfort among smokers: Comparison of smoking-specific and non-specific measures to smoking history and patterns. Addict Behav 38: 1782-1787. doi.org/10.1016/j.addbeh.2012.10.009 PMC3558609

Tidey JW, Rohsenow DJ, Kaplan GB, Swift RM, *AhnAllen CG. (2013). Separate and combined effects of very low nicotine cigarettes and nicotine replacement in smokers with schizophrenia and controls. Nicotine Tob Res, 15, 121-129.  doi: 10.1093/ntr/nts098  PMC3524060

*Dolan SL, Rohsenow DJ, Martin RA, Monti PM.  (2013). Urge-specific and lifestyle coping strategies of alcoholics: relationships of specific strategies to treatment outcome.   Drug Alcohol Depend, 213, 8-14.  PMC3505227.

Rohsenow DJ. (2013). Cue exposure treatments for substance use disorders.  In P. M. Miller (Ed.), Interventions for Addiction: Comprehensive Addictive Behaviors and Disorders. San Diego: Elsevier, pp. 29-35.

MacKillop J, Howland J, Rohsenow DJ, Few L, Amlung M, Metrik J, Calise TV. (2012). Initial development of a measure of expectancies for combinations of alcohol and caffeine: The Caffeine+Alcohol Combined Effects Questionnaire (CACEQ).  Exp Clin Psychopharm, 20, 466-472.  PMID: 23230858.

Jackson KM, Rohsenow DJ, Piasecki TM, Howland J, *Richardson AE. (2013). Tobacco smoking’s role in hangover symptoms among university students.   J Stud Alc Drugs, 74, 41-49.  PMC3517263.   

Kahler CW, McHugh RK, Metrik J, Spillane NS, Rohsenow DJ. (2013). Breath holding duration and self-reported smoking abstinence intolerance as predictors of smoking lapse behavior in a laboratory analog task. Nicotine & Tobacco Research, 6, 1151-1154. PMC3646641.

Becker SJ, Spirito A, Hernandez L, Barnett NP, Eaton CA, Lewander W, Rohsenow DJ, Monti PM. (2012).  Trajectories of adolescent alcohol use after brief treatment in an emergency department. Drug Alcohol Depend, 125, 103-109. PMC3419330

Rohsenow DJ, Howland J, Winter M, Bliss CA, Littlefield CA, Heeren TC, *Calise TV. (2012). Hangover sensitivity after controlled alcohol administration as predictor of post-college drinking. J Abnorm Psychol 121, 270-275 doi: 10.1037/a0024706 PMC4043292.

Colby SM, *Nargiso J, Tevyaw TO, Barnett NP, Metrik J, Lewander W, Woolard RH, Rohsenow DJ, Monti PM. (2012).  Enhanced motivational interviewing versus brief advice for adolescent smoking cessation: Results from a randomized clinical trial. Addic Behav 37, 817-823.  PMC3356495.

Kahler CW, Metrik J, Spillane NS, Leventhal AM, McKee SA, Tidey JW, McGeary JE, Knopik VS, Rohsenow DJ (2012).  Sex differences in stimulus expectancy and pharmacological effects of alcohol on smoking lapse risk in a laboratory analogue study.  Psychopharmacology 222, 71-80. PMC3687530.

Metrik J, Kahler CW, Reynolds B, McGeary JE, Monti PM, Haney M, de Wit H, Rohsenow DJ. (2012). Balanced-placebo design with marijuana: Pharmacological and expectancy effects on impulsivity and risk taking.  Psychopharmacology 223, 489-499.    PMC3829473

Tidey JW, Rohsenow DJ, Kaplan GB, Swift RM, Reid N.  (2011). Effects of contingency management and bupropion on cigarette smoking in smokers with schizophrenia. Psychopharmacology, 217, 179-287. PMC3640631.

Howland J,  Rohsenow DJ. (2012). Experimental methods.  In G. Li & S. P. Baker (eds.), Injury research: Theories, methods, and approaches. New York: Springer. (pp. 187-201)

*Lee CS, López SR, Hernández L, Colby SM, Caetano R, Borelli B, Rohsenow D. (2011). A cultural adaptation of motivational interviewing to address heavy drinking among Hispanics. Cultur Divers Ethnic Minor Psychol, 17, 317-324. PMC3315590

Martin RA, *MacKinnon SV, Johnson JE, Myers MG, Cook TAR, Rohsenow DJ. (2011). The Alcohol Relapse Situation Appraisal Questionnaire: Development and validation. Drug Alcohol Depend, 116(1), 45-51.  PMC3105175.

Martin RA, MacKinnon S, Johnson J, Rohsenow DJ. (2011). Purpose in life predicts treatment outcome among adult cocaine abusers in treatment. J Subst Abuse Treat, 40, 183-188. PMC3031725.

Spirito A, Sindelar-Manning H, Colby SM, Barnett NP, Lewander W, Rohsenow DJ, Monti PM. (2011). Individual and family motivational interventions for alcohol-positive adolescents treated in an emergency department: Results of a randomized clinical trial. Arch Ped Adol Med,165(3), 269-274.  PMC journal in progress.

Arnedt T, Rohsenow DJ, *Almeida B, Hunt S, Gokhale M, Howland JH. (2011). Sleep following alcohol intoxication in healthy young adults: Effects of sex and family history of alcoholism. Alcohol Clin Exp Res, 35(5), 870-878. PMC3083467

Howland J, Rohsenow DJ, Arnedt TA, Bliss CA, Hunt SK, *Calise TV, Heeren T, Winter M, Littlefield C, Gottlieb DJ. (2011). The acute effects of caffeinated vs. non-caffeinated alcoholic beverage on driving performance and attention/reaction time. Addiction 106(2), 335-341. PMID: 21134017.

Howland J, Rohsenow DJ, *Calise TV, MacKillop J, Metrik J. (2011). Caffeinated alcoholic beverages: An emerging public health problem. Amer Journal Prev Med 40(2), 268-271. PMID: 21238877. 

Metrik J, Kahler, CW, McGeary J, Monti PM, Rohsenow DJ. (2011). Acute effects of marijuana smoking on negative and positive affect. J Cogn Psychother, 25(1), 1-16. PMC3852154.

Howland J, Rohsenow DJ, Bliss CA, *Almeida AB, *Calise TV, Heeren T, Winter M. (2010). Hangover predicts residual alcohol effects on psychomotor vigilance the morning after intoxication.  J Addict Res Ther 1:101. doi:10.4172/2155-6105.1000101. PMC3105242

Rohsenow DJ, Howland J. (2010).  The role of beverage congeners in hangover and other residual effects of alcohol intoxication. Curr Drug Abuse Rev 3: 76-79. PMID:  20712591

Verster JC, Stephens R, Penning R, Rohsenow D, et al. (2010). The alcohol hangover research group consensus statement on best practice in alcohol hangover research. Curr Drug Abuse Rev 3: 116-126. PMID:  20712593

Sirota AD, Rohsenow DJ, MacKinnon SV, Martin RA, Eaton CA, Kaplan GB, Monti PM, Tidey JW, Swift RM. (2010). Intolerance for Smoking Abstinence Questionnaire: Psychometric properties and relationship to tobacco dependence and abstinence.  Addic Behav, 35, 686-693. PMCID: PMC3746812

*Neighbors CJ, Barnett NP, Rohsenow DJ, Colby SM, Monti PM. (2010). Cost-effectiveness of a motivational intervention for alcohol-involved youth in a hospital Emergency Department.  J Stud Alc Drugs, 71, 384-394.  PMC2859787

Rohsenow DJ, Howland J, Arnedt JT, *Almeida AB, *Greece J, Minsky S, Kempler CG, Sales, S. (2010). Intoxication with bourbon versus vodka: effects on hangover, sleep and next-day neurocognitive performance in young adults.  Alc Clin Exp Res, 34, 509-518.   PMC3674844 

Howland J, Rohsenow DJ, *Greece JA., *Littlefield CA, *Almeida AB, Heeren T, Winter M, Bliss CA, Hunt S, Hermos J. (2010). The effects of binge drinking on college students’ next-day academic test-taking performance and mood state. Addiction, 105, 655-665.  PMC2859622

Colby SM, Leventhal AM, Brazil L, Lewis-Esquerre J, Stein LAR, Rohsenow DJ, et al. (2010).  Smoking abstinence and reinstatement effects in adolescent cigarette smokers. Nicotine Tob Res,12, 19-28.  PMC2902909

Barnett NP, Apodaca TR, Magill M, Colby SM, Gwaltney C, Rohsenow D, Monti, PM.  (2010). Mediators and moderators of two brief interventions for alcohol in the emergency room.  Addiction, 105, 452–465 PMC2858352

*Ray LA, Miranda Jr R, Tidey JW, McGeary JE, MacKillop J, Gwaltney CJ, Rohsenow DJ, Swift RM, Monti PM. (2010). Polymorphisms of the μ-opioid receptor and dopamine D4 receptor genes and subjective responses to alcohol in the natural environment. J Abnormal Psychol, 119, 115-125.  PMC3703617

MacKillop J, Miranda R Jr. Monti PM, *Ray LA, Murphy JG, Rohsenow DJ, McGeary JE, Swift RM, Tidey JW, Gwaltney CJ. (2010). Alcohol demand, delayed reward discounting, and mediation by craving in individuals with alcohol use disorders. J Abn Psychol, 119, 106-114.  PMC2862264

Rohsenow DJ, Howland JH. (2010). Impaired the morning after intoxication: Implications for policy. Brown University Digest of Addiction Theory and Application, 29 (5), 8.

Metrik,J, Rohsenow DJ, Monti PM, McGeary J, *Cook TAR., de Wit, H, Haney, M, Kahler, C .(2009). Effectiveness of a marijuana expectancy manipulation: Piloting the balanced-placebo design for marijuana.  Exp Clin Psychopharm, 17, 217-225.  PMC2810847

Ray LA, Miranda R Jr, MacKillop J, McGeary JE., Tidey JW, Rohsenow DJ, et al. (2009).   A preliminary pharmacogenetic investigation of adverse events from topiramate in heavy drinkers.  Exp Clin Psychopharm, 17,122-129. PMC3682424

Tidey JW, Rohsenow DJ. (2009). Smoking expectancies and intention to quit in smokers with schizophrenia, schizoaffective disorder and non-psychiatric controls. Schiz Res, 115, 310-316.  PMC2795352

Magill, M., Barnett, N. B., et al. (2009). The role of marijuana use in brief motivational intervention with young adult drinkers treated in an emergency department.  J Stud Alc Drugs, 70, 409-413. PMC2670746

*Tevyaw TO, Colby S, Tidey JW, Kahler CW, Rohsenow DJ, Barnett NP, Gwaltney CJ, Monti PM. (2009). Contingency management and motivational enhancement: A randomized clinical trial for college student smokers. Nicotine Tob Res, 11(6):739-49.  PMC2688604

Zywiak WH, Neighbors CJ, Martin RA, *Johnson JE, Eaton CA, Rohsenow DJ. (2009). The Important People Drug and Alcohol Interview: Psychometric properties, predictive validity, and implications for treatment. J Subst Abuse Treat, 36, 321–330. PMC2774263

Tidey JW, Rohsenow DJ.  (2009). Intention to quit moderates the effect of bupropion on smoking urge. Nicotine Tob Res, 11(3):308-12.  PMC2666376

Rohsenow DJ. (2009).  Varenicline for smoking: The hysteria and the facts.  Brown University Digest of Addiction Theory and Application, 28(6), 8.

Tidey JW, Rohsenow DJ, Kaplan GB, Swift RM, Adolfo AB. (2008). Effects of smoking abstinence, smoking cues and nicotine replacement in smokers with schizophrenia and controls. Nicotine Tob Res, 10:1047-56. PMC2952171

Rohsenow DJ, Tidey JW, Miranda R  Jr, McGeary JE, et al. (2008). Olanzapine reduces urge to smoke and nicotine withdrawal symptoms in community smokers. Exp Clin Psychopharm, 16, 215-222. PMID: 18540781

Dolan, SL, Martin, RA, Rohsenow, DJ. (2008). Self-efficacy for cocaine abstinence: pretreatment correlates and relationship to outcomes. Addic Behav, 33, 675-688.  PMC2932666. 

Howland J, Rohsenow DJ, Edwards EM. (2008). Are some drinkers resistant to hangover? A literature review.  Current Drug Abuse Reviews, 1, 42-48. PMID: 19630704

Howland J, Rohsenow D J, Allensworth-Davies D, Greece J, Almeida A, Minsky SJ, Arnedt JT, Hermos J. (2008). The incidence and severity of hangover the morning after moderate alcohol intoxication. Addiction, 103, 758-765. PMID: 18412754

Howland J, Rohsenow D J,  Minsky SJ, Snoberg J, Tagerud S, Hunt SK, Almeida A, Greece J, Allensworth-Davies D.  (2008). The effects of transdermal scopolamine on simulated ship navigation and attention/reaction time. Int J Occup Environ Health, 14, 250-256. PMID: 19043911

Miranda R Jr, Rohsenow DJ, Monti PM, Tidey J., Ray L. (2008). Effects of repeated days of smoking cue exposure on urge to smoke and physiological reactivity. Addictive Behaviors, 33, 347-353.   PMC2254225

Miranda R Jr, MacKillop J, Monti PM, Rohsenow DJ, Tidey J, Gwaltney C, Swift RM, Ray L, McGeary JE.  (2008). Effects of topiramate on urge to drink and the subjective effects of alcohol: A preliminary laboratory study. Alcohol Clin Exp Res, 32, 489-497. PMID: 18215213

Tidey JW, Monti PM, Rohsenow DJ, Gwaltney C,  Miranda R Jr, McGeary JE,  MacKillop J, Swift RM, Abrams DB, Shiffman S, Paty JA.  (2008). Moderators of naltrexone’s effects on drinking, urge and alcohol effects in the natural environment. Alcohol Clin Exp Res, 32, 58-66. PMC2743136

Rohsenow, D. J.  (2008). Substance use disorders.  In J. Hunsley & E. J. Mash (eds.), A guide to assessments that work.  New York: Oxford University Press. (pp. 319-338).

Rohsenow DJ, Martin RA, Eaton CA, Monti PM. (2007). Cocaine craving as predictor of treatment attrition and outcomes after residential treatment for cocaine dependence. J Stud Alc Drugs, 68, 641-648. PMID: 17690796

Rohsenow DJ, Miranda R Jr, McGeary JE, Monti PM. (2007). Family history and antisocial traits moderate naltrexone’s effects on heavy drinking in alcoholics. Exp Clin Psychopharm, 15, 272-281. PMID: 17563214

Rohsenow DJ, Howland J, Minsky S, Greece J, Almeida A, Roehrs TA. (2007).  The acute hangover scale: A new measure of immediate hangover symptoms. Addic Behav, 32, 1314-1320.  PMC2853365

Rohsenow DJ, Monti PM., Hutchison, K. E., Swift, R. S., MacKinnon, S. V., Sirota, A. D., & Kaplan, G. B. (2007).  High-dose transdermal nicotine and naltrexone: Effects on nicotine withdrawal, urges, smoking, and effects of smoking. Exp Clin Psychopharm, 15, 81-92. PMID:  17295587

Monti PM, Barnett, N. P., Colby, S. M., Gwaltney, C., Spirito, A., Rohsenow, D.J., & Woolard, R.   (2007). Motivational interviewing vs. feedback only in emergency care for young adult problem drinking.    Addiction, 102, 1234-1243. PMID: 17565560

Tevyaw, T. O., Gwaltney, C., Tidey, J. W., Colby, S. M., Kahler, C. W., Miranda, R., Barnett, N. P., Rohsenow, D. J., & Monti, P. M. (2007).Contingency management for adolescent smokers: An exploratory study. J Child Adol Subst Abuse,16, 23-44.

Howland J, Almeida, A., Rohsenow, D., Minsky, S., Greece, J. (2006). How safe are federal regulations on occupational alcohol use? J Pub Health Policy, 27, 389-404. PMID: 17164805

McGeary, J.E., Monti, P.M., Rohsenow, D.J., Tidey, J.W., Swift, R.M., Miranda, R., Jr. (2006). Genetic moderators of naltrexone’s effects on alcohol cue reactivity. Alcohol Clin Exp Res, 30, 1288-1296. PMID: 16899031

Martin, R. A., Rohsenow, D. J., MacKinnon, S. V., Abrams, D. A., Monti, P. M.  (2006). Correlates of motivation to quit smoking among alcohol dependent patients in residential treatment, Drug Alc Dep, 83, 73-78. PMC1570755

Rohsenow, D.J., Howland, J., Minsky, SJ, Arnedt, JT. (2006).  Effects of heavy drinking by maritime academy cadets on hangover, perceived sleep, and next day ship power plant operation.  J Stud Alc, 67, 406-415. PMID: 16608150

Tidey, J. W., Rohsenow, D. J., Kaplan, G. K., Swift, R. M. (2005).  Cigarette smoking topography in smokers with schizophrenia and matched non-psychiatric controls. Drug Alc Dep, 80, 259-265.PMID: 15869844

Tidey, J. W., Rohsenow, D. J., Kaplan, G. K., Swift, R. M. (2005). Subjective and physiological responses to smoking cues in smokers with schizophrenia.  Nicotine Tob Res, 7,421-429.  PMID: 16085510

Rohsenow DJ, * Martin RA, Monti P M. (2005). Urge-specific and lifestyle coping strategies of cocaine abusers: Relationships to treatment outcomes.  Drug Alc Dep, 78, 211-219. PMID: 15845325 

Rohsenow, D. J., Colby, S. M., Martin, R. A., & Monti, P. M. (2005). Nicotine and Other Substance Interaction Expectancies questionnaire: Relationship of expectancies to substance use.  Addict Behav, 30, 629-641. PMID: 15833569

Rohsenow DJ, Monti PM, *Martin RA, Colby SM, *Myers MG, *Gulliver SB, Brown RA, Mueller TI, Gordon A, Abrams DB.  (2004). Motivational enhancement and coping skills training for cocaine abusers:  Effects on substance use outcomes.  Addiction, 99, 862-874. PMID: 15200582

Rohsenow, D. J. (2004). What place does naltrexone have in the treatment of alcoholism? CNS Drugs, 18, 547-560. PMID: 15222772

Rohsenow, D. J., Sirota, A. D., Martin, R. A.,  Monti, P. M.  (2004). The Cocaine Effects Questionnaire for patient populations: Development and psychometric properties.  Addic Beh, 29, 537-553. PMID: 15050672

Colby, S. M., Rohsenow, D. J., Monti, P. M., Gwaltney, C., Gulliver, S. B., Abrams, D. B., Niaura, R. S., & Sirota, A. D.  (2004). Effects of tobacco deprivation on alcohol cue reactivity and drinking among young adult social drinkers. Addic Beh, 29, 879-892. PMID: 15219332

Rohsenow, DJ, Abrams, DB, Monti, PM, Colby, SM, Martin, RA, & Niaura, RS.  (2003). The Smoking Effects Questionnaire for adult populations:  Development and psychometric properties.  Addic Beh, 28, 1257-1270. PMID: 12915167

Asher, M.K., Martin, R.A., Rohsenow, D.J., MacKinnon, S.V., Traficante, R., & Monti, P.M. (2003).  Perceived barriers to quitting smoking among alcohol dependent patients in treatment.  J Subs Ab Treat, 24, 169-174. PMID: 12745034

Rohsenow, D. J., Monti, P. M., Colby, S. M., Gulliver, S. B., Swift, R. M, & Abrams, D. B.  (2003). Naltrexone treatment for alcoholics:  Effect on cigarette smoking rates.  Nicotine Tob Res, 5, 231-236. PMID: 12745496

Monti, P. M., Kadden, R. M., Rohsenow, D. J., Cooney, N. L., & Abrams, D. B.  (2002). Treating alcohol dependence:  A coping skills training guide (2nd ed.).  New York, Guilford Press.

Monti, P. M. & Rohsenow, D. J.  (2003). Coping skills training and cue exposure treatment.  In R. K. Hester & W. R. Miller (Eds.), Handbook of alcoholism treatment approaches (3rd Ed.).  New York:  Allyn & Bacon.  (pp. 213-236)

Rohsenow, D. J.  (2003). Treating smoking among special populations: An investment in public health.  Brown University Digest of Addiction Theory and Application, 21 (4).  

Rohsenow, D. J., Monti, P. M., Colby, S. M., & Martin, R. A.  (2002). Brief interventions for smoking cessation in alcoholic smokers.  Alc Clin Exp Res, 26, 1950-1951. PMID: 12500132

Hitsman, B., Abrams, DB, Shadel, WG, Niaura, R., Borrelli, B., Emmons, K. M., Brown, R. A., Swift, R. M., Monti, P. M., Rohsenow, D. J., & Colby, S. M. (2002). Depressive symptoms and readiness to quit smoking among cigarette smokers in outpatient alcohol treatment.  Psych Addic Beh, 16, 264-268. PMID: 12236463

Rohsenow DJ, Monti PM, *Rubonis AV, *Gulliver SB, Colby SM, Binkoff  A, Abrams DB.  (2001). Cue exposure with coping skills training and communication skills training for alcohol dependence:  Six and twelve month outcomes. Addiction, 96, 1161-1174. PMID: 11487422

Hutchison, KE, Swift, RS, Rohsenow, DJ, Monti, PM, Davidson, D, & Almeida, A.  (2001). Olanzapine reduces urge to drink in response to drinking cues and to a priming dose of alcohol.  Psychopharm, 155, 27-34. PMID: 11374333

Monti PM, Rohsenow DJ, Swift RM, *Gulliver SB, Colby, SM, Mueller TI, Brown RA, Gordon A, Abrams DB, Niaura RS, *Asher MK. (2001). Naltrexone and cue exposure with coping and communication skills training for alcoholics: Treatment process and one-year outcomes.  Alc Clin Exp Res, 25, 1634-1647. PMID: 11707638

Rohsenow, DJ, et al. (2000). Naltrexone’s effects on reactivity to alcohol cues among alcoholic men.  J Abn Psych, 109, 738-742. PMID: 11195999  

Howland, J., Rohsenow, D. J., Cote, J., Gomez, B., Mangione, T. W., & Laramie, A. K.  (2001). Effects of low-dose alcohol exposure on simulated merchant ship piloting by maritime cadets.  Accident Analysis and Prevention, 33, 257-265. PMID: 11204897

Howland, J., Rohsenow, D. J., Cote, J., Siegel, M., & Mangione, T. W.  (2000). Effects of low-dose alcohol exposure on simulated merchant ship handling power plant operation by maritime cadets.  Addiction, 95, 719-726.  PMID: 10885046

Senior Research Career Scientist award, Department of Veterans Affairs. Awarded April 2009.

Research Career Scientist awards, Department of Veterans Affairs, awarded April 2004 and April 1999.
Masters of Arts ad eundem, Brown University, Providence, RI. Awarded May 1991.

Fellow, Society for Research on Nicotine and Tobacco, 2020-present.

NIAAA Postdoctoral Training Fellowship. Awarded October 1977.

PROFESSIONAL SOCIETIES
Research Society on Alcoholism
College on Problems in Drug Dependence
Society for Research on Nicotine and Tobacco

Director, Training program in Substance Abuse Intervention Outcome Research, Brown University, 2003 - present. Training postdoctoral fellows in behavioral and pharmacologic approaches to assessing, studying, and intervening with substance abuse.

Member, training committee, combined T32 postdoctoral training program in alcohol and substance abuse intervention research, Brown University, about 20 years.

Mentor individual psychology residents or post-doctoral fellows in research. 

Seminars within the T32 postdoctoral training program, Brown University.