1R61AT009337-02 (Brewer) 9/15/2016 – 11/14/2018
NIH/NCCIH $290,895/year (direct costs)
Mechanisms of mindfulness for smoking cessation: optimizing quantity and quality
This project is designed to 1) confirm brain mechanistic changes in default mode network activity after app-based smoking cessation delivery, and 2) optimize mindfulness training for smokers through a combination of app engagement optimization and neurofeedback-based augmentation of mindfulness practice.
Role: PI
1R61AT009337-02S1 (Brewer) 3/15/2017 – 9/14/2018
NIH/NCCIH $39,734
Mechanisms of mindfulness for smoking cessation: optimizing quantity and quality
Provides support under the Research Supplements to Promote Diversity in Health-Related Research Program for Hanif Benoit.
Role: PI
1 R34 AT008948-02 (Hecht and Brewer) 8/1/2016 – 7/31/2018
NIH (UCSF) $99,239/year (direct costs)
Predictors of Outcomes in MBSR Participants from Teacher Factors
This project is designed to advance our knowledge of issues in mindfulness-based interventions related to what teacher factors predict participant outcomes.
Role: Co-PI
R01 AT007922-05 (Brewer) 1/1/2014-6/30/2018
NCCIH/NIH (NCE) $231,446/year (direct costs)
Augmenting Mindfulness Training Through Experience-driven Neurofeedback Devices (ATTEND)
The goal of this project is to determine if real-time neurofeedback from the posterior cingulate cortex can augment mindfulness training.
Role: PI
1R03MH112040-01 (van Lutterveld) 4/20/2017-3/31/2019
NIH/NIMH $50,000/year (direct costs)
Mindfulness meditation and real-time brain activity in schizophrenia (MARBAIS)
The major goal of this study is to investigate whether meditation quality and PCC activity are associated in schizophrenia.
Role: Co-I
UH2 AT008145-02 (Loucks, King, Britton MPI) 09/15/2015- 08/31/2020
NIH $88,281/year (direct costs)
Mindfulness Influences on Self-Regulation: Mental and Physical Health Implication
The goal of this study is to study mindfulness influences on self- regulation.
Role: Co-investigator
Fetzer Trust 6/1/2016-6/30/2019
$104,000/year (direct costs)
Next Generation Mapping of Meditation and Neurofeedback Development for Scientific and Pragmatic Use
This project is designed to validate a 32 lead EEG source estimated neurofeedback system that can give feedback from the PCC.
Role: PI
Massachusetts Tobacco Settlement Grant 11/9/2017-11/8/2019
$186,000/year (direct costs)
The main aim for this project is to define and optimize engagement strategies, answering the questions: 1) what is the best way to roll out a digital therapeutic intervention, and 2) how can we best support individuals in using and benefiting from the program. We will test multiple strategies for engaging individuals with the digital therapeutic, including targeting 1) clinicians, 2) consumers and 3) roll-out through Epic. We will test how to best support user engagement through multiple channels, including economic incentives, in-app coaching, and personalization of the app.
R41MH118130 (Brewer) 7/1/2018-6/30/2019
NIH $97,511/year (direct costs)
Developing a Novel Developing a novel digital therapeutic for the treatment of generalized anxiety disorder
The purpose of the project is to: 1) test usability and feasibility of the Unwinding Anxiety (UA) in this target population and refine the training based on user feedback, 2) collect pilot data to determine effect sizes to power a clinical trial to determine efficacy of the intervention, and (3) determine the degree to which UA targets maladaptive reinforcement learning mechanisms (i.e., worry and emotional reactivity).
Role: PI
R21DA046957 (Brewer) 7/1/2018-6/30/2020
NIH $161,054/year (direct costs)
Targeting Worry to Improve Sleep
Our aims are to 1) Determine the degree to which mindfulness training affects maladaptive reinforcement learning, and 2) Test the degree to which mindfulness training reduces worry-driven sleep disturbance.
Role: PI
Completed Research Support
1R21CA184254-01 Brewer (PI) 4/16/14-3/31/17
NCI/NIH $130,500/year (direct costs)
Mobile Mindfulness Training for Smoking Cessation
The goal of this project is to determine if mobile mindfulness training is efficacious for smoking cessation.
Role: PI
R34 DA037886-02 (Pbert/Brewer MPI) 07/01/14 – 06/30/17
NIH/NIDA $113,752/year (direct costs)
Developing a Smartphone App with Mindfulness Training for Teen Smoking Cessation
The major goal of this study is to adapt and refine an existing Craving to Quit (C2Q) app integrating mindfulness training into a smoking cessation program for use by adolescent smokers.
Role: Multiple PI
1 R34 AT006963-01A (Fulwiler, King MPI) 5/01/13-2/29/17
Neural Targets of Mindfulness for Emotional Eating
The goal of this study is to characterize the impact of Mindfulness-Based Stress Reduction on emotion regulation circuitry using fMRI and examine the association of these changes with depressive symptoms, health behaviors and maintenance of weight loss in subjects who have intentionally lost 5-10% of their weight.
Role: Co-I Agency: NCCIH/NIH
Fetzer Trust 6/1/2016-12/31/2016
Next Generation Mapping of Meditation and Neurofeedback Development for Scientific and Pragmatic Use
The goal of this study is to map discrete stages of meditation for development of neurofeedback tools.
Role: PI
K12-DA00167 8/1/08-7/31/12
NIH/NIDA
Title: Physician Scientist Training in Substance Abuse Research
PI: Rounsaville
Role: trainee
American Heart Association Garrison (PI) 1/1/14-12/31/16
Comparing mobile mindfulness training to experience sampling for smoking cessation
The goal of this project is to test a mobile mindfulness training for smoking cessation compared to an active control.
Role: Co-I Agency: AHA
goBlue Labs Brewer (PI) 12/12/12-9/11/13
EEG lead reduction project
The goal of this project is to reduce the dimensionality of EEG signals from specific brain regions associated with meditation to track and characterize relevant psychological states.
Role: PI Agency: goBlue International
1R03DA029163-01A1 2/1/11-1/31/12
NIH/NIDA
Mindfulness training for smoking cessation
The major goal of this project is to evaluate the neural activity associated with meditation training before and after undergoing 4 weeks of mindfulness training or standard smoking cessation therapy
PI: Brewer
Role: PI
Mindfulness Center at Brown
