Studying mechanisms of ovarian reserve establishment and maintenance: identifying novel regulators of the ovarian reserve, developing strategies for ovarian reserve protection during chemotherapy, and evaluating effect of ovarian reserve regulation of female lifespan and healthspan.
De La Cruz, Payton, Woodman-Sousa, Morgan F., McAdams, Julia N., Sweeney, Ellia, Hakim, Lola, Aquino, Melanie Morales, Grive, Kathryn J. "Immune checkpoint inhibitor treatment does not impair ovarian or endocrine function in a mouse model of triple negative breast cancer." [], 2024. |
Chaqour, Julienne, Ozcan, Meghan C.H., De La Cruz, Payton, Woodman-Sousa, Morgan F., McAdams, Julia N., Grive, Kathryn J. "Effects of maternal taxane chemotherapy exposure on daughters’ ovarian reserve and fertility potential." F&S Science, 2023. |
Ozcan, Meghan C. H., Chaqour, Julienne, Woodman-Sousa, Morgan F., Grive, Kathryn J. "Exposure of Early Postnatal Oocytes to Chemotherapy Alters the Potential Ovarian Reserve, According to an Ex Vivo Mouse Model." Reproductive Medicine, vol. 4, no. 4, 2023, pp. 248-258. |
Ozcan MCH, Cruz L, Woodman MF, Gundogan F, Grive KJ. "Fetal Ovarian Reserve: the Dynamic Changes in Ubiquitin C-Terminal Hydrolase L1." Reproductive sciences (Thousand Oaks, Calif.), 2023. |
Pereira C, Arroyo-Martinez GA, Guo MZ, Downey MS, Kelly ER, Grive KJ, Mahadevaiah SK, Sims JR, Faca VM, Tsai C, Schiltz CJ, Wit N, Jacobs H, Clark NL, Freire R, Turner J, Lyndaker AM, Brieno-Enriquez MA, Cohen PE, Smolka MB, Weiss RS. "Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis." eLife, vol. 11, 2022. |
Woodman, Morgan F, Ozcan, Meghan C H, Gura, Megan A, De La Cruz, Payton, Gadson, Alexis K, Grive, Kathryn J. "The requirement of ubiquitin C-terminal hydrolase L1 in mouse ovarian development and fertility." Biology of Reproduction, vol. 107, no. 2, 2022, pp. 500-513. |
Grive KJ, Sauerbrun-Cutler MT. "Resveratrol improves granulosa cell activity through mitochondrial biogenesis." Fertility and Sterility, vol. 115, no. 4, 2021, pp. 909-910. |
Grive KJ. "Pathways coordinating oocyte attrition and abundance during mammalian ovarian reserve establishment." Mol. Reprod. Dev., vol. 87, no. 8, 2020, pp. 843-856. |
Grive KJ, Hu Y, Shu E, Grimson A, Elemento O, Grenier JK, Cohen PE. "Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing." PLOS Genetics, vol. 15, no. 3, 2019, pp. e1007810. |
Grive KJ, Gustafson EA, Seymour KA, Baddoo M, Schorl C, Golnoski K, Rajkovic A, Brodsky AS, Freiman RN. "TAF4b Regulates Oocyte-Specific Genes Essential for Meiosis." PLOS Genetics, vol. 12, no. 6, 2016, pp. e1006128. |
Grive KJ, Freiman RN. "The developmental origins of the mammalian ovarian reserve." Development, vol. 142, no. 15, 2015, pp. 2554-63. |
Grive KJ, Seymour KA, Mehta R, Freiman RN. "TAF4b promotes mouse primordial follicle assembly and oocyte survival." Developmental Biology, vol. 392, no. 1, 2014, pp. 42-51. |
Mellone BG, Grive KJ, Shteyn V, Bowers SR, Oderberg I, Karpen GH. "Assembly of Drosophila centromeric chromatin proteins during mitosis." PLOS Genetics, vol. 7, no. 5, 2011, pp. e1002068. |
Studying mechanisms of ovarian reserve establishment and maintenance: identifying novel regulators of the ovarian reserve, developing strategies for ovarian reserve protection during chemotherapy, and evaluating effect of ovarian reserve regulation of female lifespan and healthspan.
Global Consortium for Reproductive Longevity & Equality Research Award: ""Revealing the Role of Ubiquitin C-Terminal Hydrolase L1 and the Ovarian Proteasome Pathway in Female Reproductive Aging"
NIH 1R01HD111322-01A1 - "Requirement for Ubiquitin C-Terminal Hydrolase function in mammalian ovarian health and fertility"
Year | Degree | Institution |
---|---|---|
2015 | PhD | Brown University |
2013 | MA | Brown University |
2009 | BS | University of Connecticut |
Postdoctoral Research Fellow | Cornell University, Reproductive Biology | 2015-2019 | Ithaca, New York, United States |
- Hartwell Postdoctoral Fellowship (2015)
- Barry Jay Rosen Memorial Award (2015)
- Ruth L. Kirschstein National Research Service Award (2013)
- Sidney Frank Fellowship (2010)
Translational Research Scholar. Women and Infants, 2019- |