Langdon, Kirsten

Kirsten Langdon

Associate Professor of Psychiatry and Human Behavior (Research), Associate Professor of Behavioral and Social Sciences (Research)

Overview

Kirsten Langdon, PhD, is a clinical psychologist at Rhode Island Hospital and an Associate Professor (Research) in the Department of Psychiatry and Human Behavior at The Warren Alpert Medical School of Brown University. She is also the Director of Research Innovation for Brown Emergency Medicine and Associate Director of the Center for Digital Health. Dr. Langdon received her doctoral degree in clinical psychology from the University of Vermont. She completed her residency in clinical psychology at The Warren Alpert Medical School of Brown University and affiliated hospitals, and a fellowship in clinical research in the National Center for PTSD Women’s Health Sciences Division at the VA Boston Healthcare System.

Brown Affiliations

On the Web

Lifespan Recovery Center

Center for Digital Health

Research

Research Overview

Dr. Langdon's research is centered on two overlapping areas: 1) elucidating the interplay of mood/anxiety-based processes and co-occurring substance use disorders through experimental paradigms, and 2) developing specialized intervention programs designed to target these malleable risk factors to improve treatment outcomes for individuals with co-occurring mood/anxiety and substance use disorders, particularly through digital health platforms. Past work has examined tobacco use among psychiatrically vulnerable populations. More recently, her work has focused on designing and testing novel strategies, delivered through digital health, to intervene with Opioid Use Disorder.

Funded Research

Current Funding:

MPI, Improving Social Connectedness through Digital Health to Enhance Recovery from OUD among the Justice Involved Population, NIDA, Grant#1R34DA058299, 6/15/2023-4/30/2026

Director, Rhode Island Hospital Injury Control Center for Biomedical Research Excellence (COBRE) – Digital Health Innovation Core, NIGMS, Grant#1P20GM139664, 4/1/2022 – 1/21/2027.

Co-I, Identifying optimal buprenorphine dosing for OUD treatment and prevention of overdose, NIDA, Grant#1UG3DA056880, 7/1/2022 - 6/30/2027.

MPI, Integrating Long-Acting Injectable Treatment to Improve Medication Adherence among Persons Living with HIV and Opioid Use Disorder. NIDA, Grant#R34DA055498, 04/01/2022-02/28/2025.

Co-I, Increasing peer support for OUD recovery during COVID-19 through digital health: A national randomized controlled trial. NIDA, Grant#R01DA054698, 8/1/2021-07/31/2026.

Co-I, A Randomized Controlled Trial to Evaluate a Trauma-Informed Partner Violence Intervention Program. PCORI. 10/01/2024-9/30/2029.

Co-I, Development and Evaluation of a Mobile Health Intervention for Co-Morbid Opioid Use Disorder and Posttraumatic Stress Disorder During Community Re-entry. NIDA, Grant#1R61DA061335-01, 9/15/2024 – 8/31/2026.

Co-I, A Randomized Trial of Chatbot for Prenatal Genetic Counseling, Grant#1R01HD111426-01A1, NICHD, 9/18/2024 - 8/31/2029.

Co-I, Diagnostic decision support systems for patients in urgent primary care or with stroke: evaluation of safety, usability and effectiveness for diagnosis, triage and patient decision making, Grant#5R01HS029513, AHRQ, 7/01/2023-5/31/2028.

Scholarly Work

Bhuptani, P., Block, A.; Jiménez Muñoz, P., Ramsey, S., Ranney, M.L., Carey, K.B., Rich, J., & Langdon, K. J. (2023). ENhancing Distress tolerance to Uplift Motivation in REcovery (iENDURE): Results from an Open Development Trial, Digital Health, Feb 22;9:20552076231158575. doi: 10.1177/20552076231158575
Scherzer, C.R., Ranney, M.L., Patena, J., Jennings, E., Langdon, K.J., Beaudoin, F.L. (2021). Peer support for opioid use disorders: Feasibility and acceptability of a moderated text-based group chat application. J Addict Res Therapy, 12(421).
Langdon, K.J., Scherzer, C., Ramsey, S., Carey, K., Rich, J., & Ranney, M. L. (2021). Feasibility and acceptability of a digital health intervention to promote engagement in and adherence to medication for opioid use disorder, Journal of Substance Abuse Treatment, 131, 1-7.
Stringer, K, Langdon, K.J., McKenzie, M., Brockman, B. (2021). Leveraging COVID-19 to sustain regulatory flexibility in the treatment of opioid use disorder, Journal of Substance Abuse Treatment, 123, 1-3.
Langdon, K.J., Ramsey, S. Scherzer, C., Carey, K. Ranney, M. L., & Rich, J. (2020). Development of an integrated digital health intervention to promote engagement in and adherence to medication for opioid use disorder. Addiction Science & Clinical Practice, 15(1):16.
Scherzer, C., Ranney, M., Jain, S., Bommaraju, S.P., Patena, J., Langdon, K., Jennings, E., Nimaja, E., Beaudoin, F. (2020). Mobile Peer-Support for Opioid Use Disorders: Refinement of an Innovative Machine Learning Tool. Journal of Psychiatry and Brain Science, 5(1):e200001.
Langdon, K.J., Dove, K., & Ramsey, S. (2019). Comorbidity of opioid- and anxiety- related symptoms and disorders. Current Opinion in Psychology, 30, 17-23.
Rogers, A.H., Bakhshaie, J., Lam, H., Langdon, K.J., Ditre, J.W., Zvolensky, M.J. (2018). Pain-related anxiety and opioid misuse in a racially/ethnically diverse young adult sample with moderate/severe pain. Cognitive Behaviour Therapy, 47, 372-382.
Zvolensky, M. J., Rosenfield, D., Garey, L., Kauffman, B. Y., Langdon, K. J., Powers, M. B., Otto, M. W., Davis, M. L., Marcus, B. H., Church, T. S., Frierson, G. M., Hopkins, L. B., Paulus, D. J., Baird, S. O., & Smits, J. A. J. (2018). Does exercise aid smoking cessation through reductions in anxiety sensitivity and dysphoria? Health Psychology, 37, 647-657.
Bakhshaie, J., Kulesz, P. A., Garey, L., Langdon, K. J., Businelle, M. S., Leventhal, A. M., Gallagher, M. W., Schmidt, N. B., Manning, K., Goodwin, R., & Zvolensky, M. J. (2018). A prospective investigation of the synergistic effect of change in anxiety sensitivity and dysphoria on tobacco withdrawal. Journal of Consulting and Clinical Psychology, 86, 69-80.
Langdon, K. J., Rubin, A., Brief, D. J., Enggasser, J., Roy, M., Solhan, M., Helmuth, E., Rosenbloom, D., & Keane, T. M. (2017). Sexual traumatic event exposure, posttraumatic stress symptomatology, and alcohol misuse among women: A critical review of the empirical literature. Clinical Psychology: Science and Practice, 24, 5–22.
Langdon, K. J., Fox, A. B., King, L. A., King, D. W., Eisen, S., & Vogt, D. (2016). Examination of the dynamic interplay between posttraumatic stress symptoms and alcohol misuse among combat-exposed Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF) Veterans. Journal of Affective Disorders, 196, 234–242.
Langdon, K. J., Farris, S. G., Hogan, J. B. D., Grover, K. W., & Zvolensky, M. J. (2016). Anxiety sensitivity in relation to quit day dropout among adult daily smokers recruited to participate in a self-guided cessation attempt. Addictive Behaviors, 58, 12-15.
Langdon, K. J., Farris, S. G., Øverup, C. S., & Zvolensky, M. J. (2016). Associations between anxiety sensitivity, negative affect, and smoking during a self-guided smoking cessation attempt. Nicotine & Tobacco Research, 18, 1188-95.
Langdon, K.J. & Leventhal, A.M. (2014). Posttraumatic stress symptoms and tobacco abstinence effects in a non-clinical sample: Evaluating the mediating role of negative affect reduction smoking expectancies. Journal of Psychopharmacology, 28, 1009-1017.
Leventhal, A.M., Ameringer, K.J., Osborn, E., Zvolensky, M.J, & Langdon, K.J. (2013). Anxiety and depressive symptoms and affective patterns of tobacco withdrawal. Drug and Alcohol Dependence, 133, 324-329.

Background

Education and Training

Year	Degree	Institution
2013	PhD	University of Vermont
2004	BS	Union College

Honors and Awards

Bruce Selya Research Excellence Award, Lifespan Hospital System

Extramural Loan Repayment Program for Clinical Researchers, National Institute on Drug Abuse (2017-2019)

Extramural Loan Repayment Program for Clinical Researchers, National Institute on Drug Abuse Renewal (2019-2020; 2020-2021)

Award of Excellence, Department of Psychiatry, Rhode Island Hospital

Early Career Investigator Award, College on Problems of Drug Dependence

Researchers@Brown