A physician-scientist, Dean Jain is internationally recognized for studies that established a central role for Kruppel-like factors, a family of DNA transcription factors, in cardiovascular biology, innate immunity, and metabolism. Prior to his appointment at Brown, Dean Jain was chief academic officer at University Hospitals health system in Cleveland, vice dean for medical sciences at Case Western Reserve University, and Harrington Endowed Scientific Director of the Harrington Discovery Institute. In these roles, he oversaw basic and clinical research, a portfolio of programs with robust federal and non-federal annual research funding, more than 200 full-time staff, and one of the nation’s largest graduate medical education programs, with over 1,100 residents and fellows.
Nationally, Jain’s clinical and academic contributions have been recognized through numerous honors including election to the National Academy of Medicine, the American Society for Clinical Investigation — an organization for which he is a past president— the Association of American Physicians, and the Association of University Cardiologists. In 2017, Jain and five colleagues founded the Physician-Scientist Support Foundation, a nonprofit that strives to build a sustainable and diverse physician-scientist workforce through financial and research support for fundamental discoveries that improve human health.
Dean Jain has a distinguished record of successfully training independent investigators, many of whom have established independent research programs with R-level funding at leading academic medical centers including Harvard Medical School, University of California San Francisco, University of Pennsylvania, Baylor College of Medicine, Emory University, Case Western Reserve University, and the University of Tokyo. He served as principal investigator of a National Institutes of Health T32 grant focused on the training of pre-doctoral and post-doctoral candidates.
After earning a bachelor’s degree in biochemistry from the University of Buffalo, Dean Jain earned his medical degree from the University of Buffalo School of Medicine. He completed residency in internal medicine at the Beth Israel Deaconess Medical Center in Boston and fellowships in research and cardiovascular disease at Harvard School of Public Health and Brigham and Women’s Hospital. He subsequently joined the Cardiovascular Division at Brigham and Women’s and was an assistant professor at Harvard Medical School until moving to Case Western Reserve and University Hospitals in 2006.