Matthew I. Quesenberry Assistant Professor of Medicine

Dr. Quesenberry's main research interests focus on benign and malignant hematology, as well as improving medical education. He's also interested in medical humanities and it's incorporation into the oncology curriculum to improve communication skills and empathy. His most recent research efforts include looking at microvesicles as a biomarker for head trauma, involvement in cellular immunotherapy for refractory hematologic malignancies, and implementation of an adult multidisciplinary sickle cell program. He is also interested in palliative care research and ways in which oncologists can improve communication skills in regards to talking about difficult topics such as prognosis and dying.

Brown Affiliations

Research Areas

scholarly work

Ferri's Clinical Advisor 2014. In preparation .

Sood R, Makalowska I, Carpten JD, Robbins CM, Stephan DA, Connors TD, Morgenbesser SD, Su K, Pinkett HW, Graham CL, Quesenberry MI, Baxevanis AD, Klinger KW, Trent JM, Bonner TI. The human RGL (RalGDS-like) gene: cloning, expression analysis and genomic organization. Biochim Biophys Acta. 2000 Apr 25;1491(1-3):285-8.

Stephan D A, Gillanders E, Vanderveen D, Freas-Lutz D, Wistow G, Baxevanis A D, Robbins C M, VanAuken A, Quesenberry M I, Bailey-Wilson J, et al. Progressive juvenile-onset punctate cataracts caused by mutation of the gammaD-crystallin gene. Proc Natl Acad Sci USA. 1999;96:1008–1012.

Quesenberry MI, Hudak C, Extranodal Diffuse Large B Cell Lymphoma presenting with Involvement of the Myocardium and Large Intestine Case Report. In preparation

Quesenberry MI, Williams ME, Prognostic Markers and Frontline Therapy of Mantle Cell Lymphoma: Progress and Controversy. In preparation

Stephan DA, Bonner TI, Robbins CR, Teslovich T, Sood R, Carpten JD, Schmeltz M, Quesenberry M, Malechek L, Vogel B, Isaacs W, and Trent JM. The Human Z47 Gene is A novel intermediate filament binding protein with high functional homology to plectin. In preparation

Physical/transcript map of the hereditary prostate cancer locus at Xq27.3-q28. D.A. Stephan, L. Malechek, D Gildea, J Smith, M. Heiskanen, M.I. Quesenberry, J Schleutker, R. Sood, H. Pinket, C.M. Robbins, N. Scott, J.D. Carpten, P. Meltzer, o. Kallioniemi, W.B. Isaacs, JM Trent. 1) Lab of Cancer Genetics, NIH/NHGRI, Bethesda, MD; 2) Department of Urology, John Hopkins University, Baltimore, MD.

research overview

Initially Dr. Quesenberry's area of research had been in cancer genomics but has shifted towards clinical and translational research in hematologic malignancies and benign hematology. Other areas of research includes ways in which to better clinical education for fellows and medical residents.

research statement

Pre-IRTA student research assistant at The National Institutes of Health┬ŚNational Human Genome Project: Prostate Investigative Group. NIH-NHGRI, Bethesda MD 1997-1999 and summer of 2000. Worked with Dr. Dietrich Stephan under Dr. Jeffery Trent and Dr. Francis Collins to try and map out and find the gene or genes that were responsible for hereditary prostate cancer.

Worked with Dietrich Stephan on mapping out and finding the gene that is responsible for Progressive Juvenile-Onset punctuate cataracts--1999

Co-Clinical Investigator Phase II single Arm study looking at the combination of Lenalidomide with dose optimized Rituxan in relapsed CLL. Clinical Protocol University of Virginia in preparation 2011

C0-Investigator- Microvesicles in Saliva as a biomarker for head trauma. On going starting in 2012

Piloting humanities based curriculum in oncology that will help build communication skills in terms of dealing with difficult topics like termination of therapy and dying.

funded research

NIH--for Human Genome Project in 1997-2000
Institutional