Roy K. Aaron, M.D. is professor of orthopaedic surgery and professor of molecular pharmacology, physiology and biotechnology. He is Director of the Brown/VA Center for Restorative and Regenerative Medicine and the Brown Program for Recovery from Trauma. Dr. Aaron is also the Director of the Orthopaedic Cell Biology Laboratory and of Clinical Research for the Department.
Dr. Aaron graduated from Lafayette College and SUNY Downstate Medical School. He did an internship in internal medicine at Montefiore Hospital - Albert Einstein College of Medicine in New York and a year of general surgery residency at the U.S. Public Health Service Hospital, Staten Island, New York. Dr. Aaron completed a surgical research fellowship at the National Institutes of Health, a residency in the Harvard Orthopaedic Program and a fellowship in arthritis surgery at the Robert Brigham Hospital in Boston. He then returned to NIH for three years of research in cartilage biochemistry.
Dyke, J.P., R.K. Aaron. Non-invasive methods of measuring bone blood perfusion. Ann. NY Acad. Sci.1192:95-102; 2010.
Gerin-Lajoie, M., D. McK. Ciombor, W. Warren, R.K. Aaron. Using ambulatory virtual environments for the assessment of functional gait impairment: A proof-of-concept study. Gait and Posture. 31: 533-536; 2010.
Puckett, S., P.P. Lee, D. McK. Ciombor, R.K. Aaron, T. Webster. Nanotextured titanium surfaces for enhancing skin growth on transcutaneous osseointegrated devices. Acta Biomaterialia. 6: 2352-62; 2010.
Bilgen B, Y. Ren, M. Pei, R.K. Aaron, D. McK. Ciombor. CD14-Negative isolation enhances chondrogenesis in synovial fibroblasts. Tissue Eng. 15: 3261-3270; 2009.
Lee, J.H., J. Dyke, D. Ballon, D. McK. Ciombor, M. Rosenwasser, R.K. Aaron. Subchondral fluid dynamics in a model of osteoarthritis: Use of dynamic contrast-enhanced magnetic resonance imaging. Osteoarthritis and Cartilage. 17: 1350-1355; 2009.
Lee, J.H., J. Dyke, D. Ballon, D. McK. Ciombor, G. Tung, R.K. Aaron. Assessment of bone perfusion with contrast-enhanced magnetic resonance imaging. Ortho Clin N Am. 40: 249-257; 2009.
Covey, D. C. Born, R.K. Aaron, D. McK. Ciombor, et. al. Regenerative and restorative techniques to treat severe limb trauma orthopaedic war injuries: New developments in treatments and research. AAOS Instructional Course Lectures. 58: 117-129; 2009.
Jaklenec A, A. Hinckfuss, B. Bilgen, D. McK. Ciombor, R.K. Aaron, E. Mathiowitz. Sequential release of bioactive IGF-I and TGF-beta(1) from PLGA microsphere-based scaffolds. Biomaterials.10:1518-25; 2008.
Covey, D. R.K. Aaron, C. Born, J. Calhoun, T. Einhorn, H. Frisch, L. Levin, M. Mazurek, E. Schwartz, J. Wenke, E. Powell. Orthopaedic war injuries from combat casualty care to definitive treatment: a current review of the basic science, clinical advances and research opportunities. AAOS Instructional Course Lectures. 57: 65; 2008.
Aaron, R.K., J. Dyke, D. McK. Ciombor, D. Ballon, J. Lee, E. Jung, G. Tung Perfusion abnormalities in subchondral bone association with marrow edema, osteoarthritis and avascular necrosis. Ann. NY Acad. Sci. 117: 124-137; 2007.
Aaron, R.K. and D. McK. Ciombor. Orthopaedic complications of solid organ transplantation. Surg. Clin. North America. 86: 1237-1255; 2006.
Aaron, R.K. and R. Gray. Osteonecrosis: Etiology, Natural History, Pathophysiology and Diagnosis. In: The Adult Hip, 2nd edition. Eds: J. Callaghan, A. Rosenberg, and H. Rubash. Lippincott Williams & Wilkins, Philadelphia, PA. v.1 pg 463-476; 2006.
Aaron, R.K., H. Herr, D. McK. Ciombor, L. Hochberg, J. Donoghue, C. Briant, J. Morgan, M. Ehrlich. Horizons in prosthetic development for restoration of limb function. J Am Acad Orthop Surg. 14: S198-204: 2006
Paek, H.J., A.B. Campaner, J.L. Kem, L. Golden, R.K. Aaron, D. McK. Ciombor, J. Morgan, M. Lysaght. Microencapsulated cells genetically modified to overexpress human transforming growth factor-beta1: viability and functionality in allogeneic and xenogeneic implant models. Tissue Engin. 12(7): 1733-9; 2006
Aaron, R.K., D. McK. Ciombor, S. Wang. Clinical biophysics: The promotion of skeletal repair by physical forces. Ann. N.Y. Acad. Sci. 1068: 513-531; 2006
Aaron, R.K., A. Skolnick, S. Reinert, D. McK. Ciombor. Arthroscopic debridement for osteoarthritis of the knee. J. Bone Joint Surg. 88A: 936-943; 2006
Ciombor, D. McK., A Jaklenec, A. Liu, C. Thanos, N. Rahman, P.Weston, R. Aaron, E. Mathiowitz. Encapsulation of BSA using a W/O/O emulsion solvent removal method. J. Microencap. 23 (2): 183-194; 2006
Paek, H.J., A.B. Campaner, J.L. Kim, R.K. Aaron, D. Ciombor, J. Morgan, M. Lysaght. In-vitro characterization of TGFβ1 release from genetically modified fibroblasts in calcium alginate microcapsules. ASAIO. 51: 379-384, 2005.
Aaron, R.K. and M. Bolander (eds.). Physical Regulation of Skeletal Repair. American Academy of Orthopaedic Surgeons, Chicago, IL. 2005.
Ciombor, D. McK., R.K. Aaron, S. Wang, and B. Simon. Modification of osteoarthritis in the guinea pig – A morphological study. Osteoarthritis and Cartilage. 11: 455-462; 2003.
Lieberman, J., D. Berry, M. Mont, R.K. Aaron, et al. Osteonecrosis of the hip: Management in the 21st century. J. Bone Joint Surg. 84: 834-853; 2002.
Aaron, R.K., S. Wang, and D. McK. Ciombor. Upregulation of basal TGF beta levels coincident with chondrogenesis. Implications for skeletal repair and tissue engineering. J. Orthop. Res. 20: 233-240; 2002.
|Guest Investigator||National Institute of Dental Research, National Institutes of Health, proteoglycan||1978-1981||Bethesda, MD|
|Fellow||Robert Breck Brigham Hospital, arthritis surgery||1977-1978||Boston, MA|
|Resident||Massachusetts General Hospital, Orthopaedics||1974-1977||Boston, MA|
|Clinical Associate||National Cancer Institute, National Institutes of Health, surgery||1971-1973||Bethesda, MD|
|Resident||U.S. Public Health Service Hospital, surgery||1970-1973||New York, NY|
|Intern||Montefiore Medical Center, medicine||1969-1970||New York, NY|
|Medical License||Rhode Island||1981-|
|Certification||American Board of Orthopaedic Surgery, Orthopaedic surgery||1979-|
|Attending Orthopaedic Surgeon. Lifespan Academic Medical Center, 1981-|