Richard N. Freiman Associate Professor of Medical Science

Richard Freiman is molecular geneticist studying fundamental mechanisms of transcriptional regulation in mammalian development and human disease. Before joining the Brown faculty in 2003, Dr. Freiman completed graduate training in mechanisms garnering eukaryotic transcriptional regulation. He received his Ph.D. in Genetics from SUNY Stony Brook in 1997. His thesis research, conducted at Cold Spring Harbor Laboratory, involved elucidation of critical host cell-viral interactions regulating viral and cellular gene expression programs. In 1998, he moved to UC Berkeley where he conducted postdoctoral studies on mechanisms of tissue-specific gene expression. This work led to the discovery that components of general transcription factor complexes play direct and selective roles in mammalian development. He continues this research at Brown, using gene targeting in the mouse as the primary tool to characterize transcriptional regulators in mammalian reproduction and development. His recent work focuses on understanding the molecular etiology of infertility and ovarian cancer in women and mechanisms of spermatogonial stem cell regulation in men. He teaches courses on cell and molecular biology and stem cells.

Brown Affiliations

Research Areas