Assistant Professor of Health Services, Policy and Practice

Overview

My primary research interests lie at the interface of health decision science and applied mathematics.  I am interested in the analysis of cancer epidemiology data using mechanistic models of carcinogenesis to reverse-engineer the biological mechanisms of cancer progression and to identify approaches for more effective cancer control strategies.  Currently, I am investigating how different assumptions on the timing of the cancer cells spread and how the metastasis process is modeled may lead to biased estimates of the benefit of mammography and adjuvant treatment among early stage breast cancer patients.  For this purpose, I have developed a multiscale model that integrates biological data and the observed epidemiological data.  This modeling framework can facilitate the inclusion of recent advances in the field of cancer biology coupled with epidemiological data thereby permitting a more evidence-based and comprehensive evaluation of cancer control strategies.

I am also interested in developing novel methodologies in or porting existing methodologies from applied mathematics, machine learning, and bayesian statistics for application in decision modeling.  These topics include the use of stochastic differential equation for decision modeling and the application of approximation theory to computationally expensive simulation models.

I have extensive modeling experiences in breast cancer.

My current reseach projects include: 

  1. Developing a method for adaptively determining the cycle size in Markov models
  2. Estimating the survival benefits and the quality of life impact of contralateral prophylactic mastectomy using decision models
  3. Developing the principles of statistical calibration of decision models
  4. Developing multiple-time-scale method for decision modeling
  5. Using copula for representing decision tree model and synthetic cohort creation
  6. Developing a population health planner to assist decisionmakers in prioritizing public health strategies in the context of constrained resources and limited expertise


I received my Ph.D. in health services research, policy, and administration with a focus on health decision science from the University of Minnesota, Twin-Cities, under the supervision of Professor Karen M. Kuntz.

I am always seeking for new challenges and problems to solve.  I am based in Providence, RI, and Neuchatel, Switzerland.  I am also open for collaborations in particular any project ideas related to my home country, Indonesia.

Brown Affiliations

Research Areas