Sean Lawler Ph.D leads the Brain Cancer Therapy Lab in the Department of Pathology and Laboratory Medicine at Brown University. He is also co-leader of the CNS Cancer Translational Disease Research Group at the Legorreta Cancer Center, and co-Director of the Therapeutic Sciences Graduate Program at Brown University.
The Lawler Lab investigates therapeutic approaches for the treatment of Brain Cancer, from preclinical models, to the analysis of patient tumors. Our major interests are 1) Drug delivery across the blood-brain barrier for cancer treatment in the brain, 2) Harnessing innate immune mechanisms to enable the effective application of immunotherapies for brain cancer, and 3) understanding the effects of a common pathogen, cytomegalovirus, on the growth of the malignant brain tumor glioblastoma.
Our goal is to design new and effective next generation therapeutic approaches for these extremely challenging diseases.