Kinsella, Timothy

Timothy Kinsella

Professor Emeritus of Radiation Oncology

Overview

Dr. Kinsella is an internationally recognized radiation oncologist with clinical expertise in the treatment of sarcomas, brain tumors, lymphomas, gastrointestinal cancers and pediatric cancers. He has extensive laboratory expertise in the development of intraoperative radiotherapy, radiation sensitizing drugs, and small molecules that modify DNA repair processing of radiation damage, and has been the recipient of numerous grants including NIH funding for over 30 years. He has published over 350 articles, chapters and books. Dr. Kinsella has served on numerous advisory boards, including the NCI Board of Scientific Advisors, currently serves on the editorial boards of nine scientific journals including Cancer Research, Seminars in Radiation Oncology and is the Editor-in-Chief of Frontiers in Radiation Oncology. Prior to joining Rhode Island Hospital and Brown University as a Research Scholar Professor in 2010, he was Senior Investigator and Deputy Branch Chief in Radiation Oncology at the National Cancer Institute, Chair of the Department of Human Oncology at the University of Wisconsin, founding Chair of Radiation Oncology at Case Western Reserve University, and Director of the Stony Brook University Cancer Center.

Brown Affiliations

Radiation Oncology

Publications Visualize it

Ebner DK, Gorovets D, Rava P, Cielo D, Kinsella TJ, DiPetrillo TA, Hepel JT. "Patients with Long-Term Control of Systemic Disease Are a Favorable Prognostic Group for Treatment of Brain Metastases with Stereotactic Radiosurgery Alone." World Neurosurgery, vol. 98, 2017, pp. 266-272.

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Koffer, Paul, Chan, Jason, Rava, Paul, Gorovets, Daniel, Ebner, Daniel, Savir, Guy, Kinsella, Timothy, Cielo, Deus, Hepel, Jaroslaw T. "Repeat Stereotactic Radiosurgery for Locally Recurrent Brain Metastases." World Neurosurgery, vol. 104, 2017, pp. 589-593.

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Yu E, Koffer PP, DiPetrillo TA, Kinsella TJ. "Incidence, Treatment, and Survival Patterns for Sacral Chordoma in the United States, 1974-2011." Frontiers in Oncology, vol. 6, 2016, pp. 203.

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Gorovets D, Rava P, Ebner DK, Tybor DJ, Cielo D, Puthawala Y, Kinsella TJ, DiPetrillo TA, Wazer DE, Hepel JT. "Predictors for long-term survival free from whole brain radiation therapy in patients treated with radiosurgery for limited brain metastases." Frontiers in Oncology, vol. 5, 2015, pp. 110.

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Punsoni M, Donahue JE, Elinzano HD, Kinsella T. "Updates in Molecular Pathology of Central Nervous System Gliomas in Adults." Rhode Island medical journal (2013), vol. 98, no. 11, 2015, pp. 17-9.

PubMed

Jeyapalan, Suriya, Boxerman, Jerrold, Donahue, John, Goldman, Marc, Kinsella, Timothy, Dipetrillo, Thomas, Evans, Devon, Elinzano, Heinrich, Constantinou, Maria, Stopa, Edward, Puthawala, Yakub, Cielo, Deus, Santaniello, Alyson, Oyelese, Adetokunbo, Mantripragada, Kalyan, Rosati, Kayla, Isdale, Debora, Safran, Howard. "Paclitaxel poliglumex, temozolomide, and radiation for newly diagnosed high-grade glioma: a Brown University Oncology Group Study." American Journal of Clinical Oncology, vol. 37, no. 5, 2014, pp. 444-449.

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Chan J, Kinsella MT, Willis JE, Hu H, Reynolds H Jr, Delaney C, McCulla A, Deharo S, Ahdesmäki M, Allen WL, Johnston PG, Kinsella TJ. "A Predictive Genetic Signature for Response to Fluoropyrimidine-Based Neoadjuvant Chemoradiation in Clinical Stage II and III Rectal Cancer." Frontiers in Oncology, vol. 3, 2013, pp. 288.

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Gurkan-Cavusoglu E, Avadhani S, Liu L, Kinsella TJ, Loparo KA. "Developing an in silico model of the modulation of base excision repair using methoxyamine for more targeted cancer therapeutics." IET systems biology, vol. 7, no. 2, 2013, pp. 27-37.

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Gurkan-Cavusoglu E, Schupp JE, Kinsella TJ, Loparo KA. "Quantitative analysis of the effects of iododeoxyuridine and ionising radiation treatment on the cell cycle dynamics of DNA mismatch repair deficient human colorectal cancer cells." IET systems biology, vol. 7, no. 4, 2013, pp. 114-24.

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Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC Jr, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, Garcia-Manero G, Garcia-Marcos M, Garmyn M, Gartel AL, Gatti E, Gautel M, Gawriluk TR, Gegg ME, Geng J, Germain M, Gestwicki JE, Gewirtz DA, Ghavami S, Ghosh P, Giammarioli AM, Giatromanolaki AN, Gibson SB, Gilkerson RW, Ginger ML, Ginsberg HN, Golab J, Goligorsky MS, Golstein P, Gomez-Manzano C, Goncu E, Gongora C, Gonzalez CD, Gonzalez R, González-Estévez C, González-Polo RA, Gonzalez-Rey E, Gorbunov NV, Gorski S, Goruppi S, Gottlieb RA, Gozuacik D, Granato GE, Grant GD, Green KN, Gregorc A, Gros F, Grose C, Grunt TW, Gual P, Guan JL, Guan KL, Guichard SM, Gukovskaya AS, Gukovsky I, Gunst J, Gustafsson AB, Halayko AJ, Hale AN, Halonen SK, Hamasaki M, Han F, Han T, Hancock MK, Hansen M, Harada H, Harada M, Hardt SE, Harper JW, Harris AL, Harris J, Harris SD, Hashimoto M, Haspel JA, Hayashi S, Hazelhurst LA, He C, He YW, Hébert MJ, Heidenreich KA, Helfrich MH, Helgason GV, Henske EP, Herman B, Herman PK, Hetz C, Hilfiker S, Hill JA, Hocking LJ, Hofman P, Hofmann TG, Höhfeld J, Holyoake TL, Hong MH, Hood DA, Hotamisligil GS, Houwerzijl EJ, Høyer-Hansen M, Hu B, Hu CA, Hu HM, Hua Y, Huang C, Huang J, Huang S, Huang WP, Huber TB, Huh WK, Hung TH, Hupp TR, Hur GM, Hurley JB, Hussain SN, Hussey PJ, Hwang JJ, Hwang S, Ichihara A, Ilkhanizadeh S, Inoki K, Into T, Iovane V, Iovanna JL, Ip NY, Isaka Y, Ishida H, Isidoro C, Isobe K, Iwasaki A, Izquierdo M, Izumi Y, Jaakkola PM, Jäättelä M, Jackson GR, Jackson WT, Janji B, Jendrach M, Jeon JH, Jeung EB, Jiang H, Jiang H, Jiang JX, Jiang M, Jiang Q, Jiang X, Jiang X, Jiménez A, Jin M, Jin S, Joe CO, Johansen T, Johnson DE, Johnson GV, Jones NL, Joseph B, Joseph SK, Joubert AM, Juhász G, Juillerat-Jeanneret L, Jung CH, Jung YK, Kaarniranta K, Kaasik A, Kabuta T, Kadowaki M, Kagedal K, Kamada Y, Kaminskyy VO, Kampinga HH, Kanamori H, Kang C, Kang KB, Kang KI, Kang R, Kang YA, Kanki T, Kanneganti TD, Kanno H, Kanthasamy AG, Kanthasamy A, Karantza V, Kaushal GP, Kaushik S, Kawazoe Y, Ke PY, Kehrl JH, Kelekar A, Kerkhoff C, Kessel DH, Khalil H, Kiel JA, Kiger AA, Kihara A, Kim DR, Kim DH, Kim DH, Kim EK, Kim HR, Kim JS, Kim JH, Kim JC, Kim JK, Kim PK, Kim SW, Kim YS, Kim Y, Kimchi A, Kimmelman AC, King JS, Kinsella TJ, Kirkin V, Kirshenbaum LA, Kitamoto K, Kitazato K, Klein L, Klimecki WT, Klucken J, Knecht E, Ko BC, Koch JC, Koga H, Koh JY, Koh YH, Koike M, Komatsu M, Kominami E, Kong HJ, Kong WJ, Korolchuk VI, Kotake Y, Koukourakis MI, Kouri Flores JB, Kovács AL, Kraft C, Krainc D, Krämer H, Kretz-Remy C, Krichevsky AM, Kroemer G, Krüger R, Krut O, Ktistakis NT, Kuan CY, Kucharczyk R, Kumar A, Kumar R, Kumar S, Kundu M, Kung HJ, Kurz T, Kwon HJ, La Spada AR, Lafont F, Lamark T, Landry J, Lane JD, Lapaquette P, Laporte JF, László L, Lavandero S, Lavoie JN, Layfield R, Lazo PA, Le W, Le Cam L, Ledbetter DJ, Lee AJ, Lee BW, Lee GM, Lee J, Lee JH, Lee M, Lee MS, Lee SH, Leeuwenburgh C, Legembre P, Legouis R, Lehmann M, Lei HY, Lei QY, Leib DA, Leiro J, Lemasters JJ, Lemoine A, Lesniak MS, Lev D, Levenson VV, Levine B, Levy E, Li F, Li JL, Li L, Li S, Li W, Li XJ, Li YB, Li YP, Liang C, Liang Q, Liao YF, Liberski PP, Lieberman A, Lim HJ, Lim KL, Lim K, Lin CF, Lin FC, Lin J, Lin JD, Lin K, Lin WW, Lin WC, Lin YL, Linden R, Lingor P, Lippincott-Schwartz J, Lisanti MP, Liton PB, Liu B, Liu CF, Liu K, Liu L, Liu QA, Liu W, Liu YC, Liu Y, Lockshin RA, Lok CN, Lonial S, Loos B, Lopez-Berestein G, López-Otín C, Lossi L, Lotze MT, Lőw P, Lu B, Lu B, Lu B, Lu Z, Luciano F, Lukacs NW, Lund AH, Lynch-Day MA, Ma Y, Macian F, MacKeigan JP, Macleod KF, Madeo F, Maiuri L, Maiuri MC, Malagoli D, Malicdan MC, Malorni W, Man N, Mandelkow EM, Manon S, Manov I, Mao K, Mao X, Mao Z, Marambaud P, Marazziti D, Marcel YL, Marchbank K, Marchetti P, Marciniak SJ, Marcondes M, Mardi M, Marfe G, Mariño G, Markaki M, Marten MR, Martin SJ, Martinand-Mari C, Martinet W, Martinez-Vicente M, Masini M, Matarrese P, Matsuo S, Matteoni R, Mayer A, Mazure NM, McConkey DJ, McConnell MJ, McDermott C, McDonald C, McInerney GM, McKenna SL, McLaughlin B, McLean PJ, McMaster CR, McQuibban GA, Meijer AJ, Meisler MH, Meléndez A, Melia TJ, Melino G, Mena MA, Menendez JA, Menna-Barreto RF, Menon MB, Menzies FM, Mercer CA, Merighi A, Merry DE, Meschini S, Meyer CG, Meyer TF, Miao CY, Miao JY, Michels PA, Michiels C, Mijaljica D, Milojkovic A, Minucci S, Miracco C, Miranti CK, Mitroulis I, Miyazawa K, Mizushima N, Mograbi B, Mohseni S, Molero X, Mollereau B, Mollinedo F, Momoi T, Monastyrska I, Monick MM, Monteiro MJ, Moore MN, Mora R, Moreau K, Moreira PI, Moriyasu Y, Moscat J, Mostowy S, Mottram JC, Motyl T, Moussa CE, Müller S, Muller S, Münger K, Münz C, Murphy LO, Murphy ME, Musarò A, Mysorekar I, Nagata E, Nagata K, Nahimana A, Nair U, Nakagawa T, Nakahira K, Nakano H, Nakatogawa H, Nanjundan M, Naqvi NI, Narendra DP, Narita M, Navarro M, Nawrocki ST, Nazarko TY, Nemchenko A, Netea MG, Neufeld TP, Ney PA, Nezis IP, Nguyen HP, Nie D, Nishino I, Nislow C, Nixon RA, Noda T, Noegel AA, Nogalska A, Noguchi S, Notterpek L, Novak I, Nozaki T, Nukina N, Nürnberger T, Nyfeler B, Obara K, Oberley TD, Oddo S, Ogawa M, Ohashi T, Okamoto K, Oleinick NL, Oliver FJ, Olsen LJ, Olsson S, Opota O, Osborne TF, Ostrander GK, Otsu K, Ou JH, Ouimet M, Overholtzer M, Ozpolat B, Paganetti P, Pagnini U, Pallet N, Palmer GE, Palumbo C, Pan T, Panaretakis T, Pandey UB, Papackova Z, Papassideri I, Paris I, Park J, Park OK, Parys JB, Parzych KR, Patschan S, Patterson C, Pattingre S, Pawelek JM, Peng J, Perlmutter DH, Perrotta I, Perry G, Pervaiz S, Peter M, Peters GJ, Petersen M, Petrovski G, Phang JM, Piacentini M, Pierre P, Pierrefite-Carle V, Pierron G, Pinkas-Kramarski R, Piras A, Piri N, Platanias LC, Pöggeler S, Poirot M, Poletti A, Poüs C, Pozuelo-Rubio M, Prætorius-Ibba M, Prasad A, Prescott M, Priault M, Produit-Zengaffinen N, Progulske-Fox A, Proikas-Cezanne T, Przedborski S, Przyklenk K, Puertollano R, Puyal J, Qian SB, Qin L, Qin ZH, Quaggin SE, Raben N, Rabinowich H, Rabkin SW, Rahman I, Rami A, Ramm G, Randall G, Randow F, Rao VA, Rathmell JC, Ravikumar B, Ray SK, Reed BH, Reed JC, Reggiori F, Régnier-Vigouroux A, Reichert AS, Reiners JJ Jr, Reiter RJ, Ren J, Revuelta JL, Rhodes CJ, Ritis K, Rizzo E, Robbins J, Roberge M, Roca H, Roccheri MC, Rocchi S, Rodemann HP, Rodríguez de Córdoba S, Rohrer B, Roninson IB, Rosen K, Rost-Roszkowska MM, Rouis M, Rouschop KM, Rovetta F, Rubin BP, Rubinsztein DC, Ruckdeschel K, Rucker EB 3rd, Rudich A, Rudolf E, Ruiz-Opazo N, Russo R, Rusten TE, Ryan KM, Ryter SW, Sabatini DM, Sadoshima J, Saha T, Saitoh T, Sakagami H, Sakai Y, Salekdeh GH, Salomoni P, Salvaterra PM, Salvesen G, Salvioli R, Sanchez AM, Sánchez-Alcázar JA, Sánchez-Prieto R, Sandri M, Sankar U, Sansanwal P, Santambrogio L, Saran S, Sarkar S, Sarwal M, Sasakawa C, Sasnauskiene A, Sass M, Sato K, Sato M, Schapira AH, Scharl M, Schätzl HM, Scheper W, Schiaffino S, Schneider C, Schneider ME, Schneider-Stock R, Schoenlein PV, Schorderet DF, Schüller C, Schwartz GK, Scorrano L, Sealy L, Seglen PO, Segura-Aguilar J, Seiliez I, Seleverstov O, Sell C, Seo JB, Separovic D, Setaluri V, Setoguchi T, Settembre C, Shacka JJ, Shanmugam M, Shapiro IM, Shaulian E, Shaw RJ, Shelhamer JH, Shen HM, Shen WC, Sheng ZH, Shi Y, Shibuya K, Shidoji Y, Shieh JJ, Shih CM, Shimada Y, Shimizu S, Shintani T, Shirihai OS, Shore GC, Sibirny AA, Sidhu SB, Sikorska B, Silva-Zacarin EC, Simmons A, Simon AK, Simon HU, Simone C, Simonsen A, Sinclair DA, Singh R, Sinha D, Sinicrope FA, Sirko A, Siu PM, Sivridis E, Skop V, Skulachev VP, Slack RS, Smaili SS, Smith DR, Soengas MS, Soldati T, Song X, Sood AK, Soong TW, Sotgia F, Spector SA, Spies CD, Springer W, Srinivasula SM, Stefanis L, Steffan JS, Stendel R, Stenmark H, Stephanou A, Stern ST, Sternberg C, Stork B, Strålfors P, Subauste CS, Sui X, Sulzer D, Sun J, Sun SY, Sun ZJ, Sung JJ, Suzuki K, Suzuki T, Swanson MS, Swanton C, Sweeney ST, Sy LK, Szabadkai G, Tabas I, Taegtmeyer H, Tafani M, Takács-Vellai K, Takano Y, Takegawa K, Takemura G, Takeshita F, Talbot NJ, Tan KS, Tanaka K, Tanaka K, Tang D, Tang D, Tanida I, Tannous BA, Tavernarakis N, Taylor GS, Taylor GA, Taylor JP, Terada LS, Terman A, Tettamanti G, Thevissen K, Thompson CB, Thorburn A, Thumm M, Tian F, Tian Y, Tocchini-Valentini G, Tolkovsky AM, Tomino Y, Tönges L, Tooze SA, Tournier C, Tower J, Towns R, Trajkovic V, Travassos LH, Tsai TF, Tschan MP, Tsubata T, Tsung A, Turk B, Turner LS, Tyagi SC, Uchiyama Y, Ueno T, Umekawa M, Umemiya-Shirafuji R, Unni VK, Vaccaro MI, Valente EM, Van den Berghe G, van der Klei IJ, van Doorn W, van Dyk LF, van Egmond M, van Grunsven LA, Vandenabeele P, Vandenberghe WP, Vanhorebeek I, Vaquero EC, Velasco G, Vellai T, Vicencio JM, Vierstra RD, Vila M, Vindis C, Viola G, Viscomi MT, Voitsekhovskaja OV, von Haefen C, Votruba M, Wada K, Wade-Martins R, Walker CL, Walsh CM, Walter J, Wan XB, Wang A, Wang C, Wang D, Wang F, Wang F, Wang G, Wang H, Wang HG, Wang HD, Wang J, Wang K, Wang M, Wang RC, Wang X, Wang X, Wang YJ, Wang Y, Wang Z, Wang ZC, Wang Z, Wansink DG, Ward DM, Watada H, Waters SL, Webster P, Wei L, Weihl CC, Weiss WA, Welford SM, Wen LP, Whitehouse CA, Whitton JL, Whitworth AJ, Wileman T, Wiley JW, Wilkinson S, Willbold D, Williams RL, Williamson PR, Wouters BG, Wu C, Wu DC, Wu WK, Wyttenbach A, Xavier RJ, Xi Z, Xia P, Xiao G, Xie Z, Xie Z, Xu DZ, Xu J, Xu L, Xu X, Yamamoto A, Yamamoto A, Yamashina S, Yamashita M, Yan X, Yanagida M, Yang DS, Yang E, Yang JM, Yang SY, Yang W, Yang WY, Yang Z, Yao MC, Yao TP, Yeganeh B, Yen WL, Yin JJ, Yin XM, Yoo OJ, Yoon G, Yoon SY, Yorimitsu T, Yoshikawa Y, Yoshimori T, Yoshimoto K, You HJ, Youle RJ, Younes A, Yu L, Yu L, Yu SW, Yu WH, Yuan ZM, Yue Z, Yun CH, Yuzaki M, Zabirnyk O, Silva-Zacarin E, Zacks D, Zacksenhaus E, Zaffaroni N, Zakeri Z, Zeh HJ 3rd, Zeitlin SO, Zhang H, Zhang HL, Zhang J, Zhang JP, Zhang L, Zhang L, Zhang MY, Zhang XD, Zhao M, Zhao YF, Zhao Y, Zhao ZJ, Zheng X, Zhivotovsky B, Zhong Q, Zhou CZ, Zhu C, Zhu WG, Zhu XF, Zhu X, Zhu Y, Zoladek T, Zong WX, Zorzano A, Zschocke J, Zuckerbraun B. "Guidelines for the use and interpretation of assays for monitoring autophagy." Autophagy, vol. 8, no. 4, 2012, pp. 445-544.

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Du W, Kinsella TJ. "A rapid, simple DNA mismatch repair substrate construction method." Frontiers in Oncology, vol. 1, 2011, pp. 8.

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Gurkan-Cavusoglu E, Schupp JE, Kinsella TJ, Loparo KA. "Analysis of cell cycle dynamics using probabilistic cell cycle models." 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, vol. 2011, 2011, pp. 141-4.

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Zeng X, Kinsella TJ. "Impact of Autophagy on Chemotherapy and Radiotherapy Mediated Tumor Cytotoxicity: "To Live or not to Live"." Frontiers in Oncology, vol. 1, 2011, pp. 30.

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Kinsella TJ, Gurkan-Cavusoglu E, Du W, Loparo KA. "Integration of Principles of Systems Biology and Radiation Biology: Toward Development of in silico Models to Optimize IUdR-Mediated Radiosensitization of DNA Mismatch Repair Deficient (Damage Tolerant) Human Cancers." Frontiers in Oncology, vol. 1, 2011, pp. 20.

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Kinsella TJ, Baron ED, Colussi VC, Cooper KD, Hoppel CL, Ingalls ST, Kenney ME, Li X, Oleinick NL, Stevens SR, Remick SC. "Preliminary clinical and pharmacologic investigation of photodynamic therapy with the silicon phthalocyanine photosensitizer pc 4 for primary or metastatic cutaneous cancers." Frontiers in Oncology, vol. 1, 2011, pp. 14.

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Kinsella TJ. "Radiation oncology: today and tomorrow." Frontiers in Oncology, vol. 1, 2011, pp. 7.

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Chapman TR, Kinsella TJ. "Ribonucleotide reductase inhibitors: a new look at an old target for radiosensitization." Frontiers in Oncology, vol. 1, 2011, pp. 56.

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Zeng X, Kinsella TJ. "BNIP3 is essential for mediating 6-thioguanine- and 5-fluorouracil-induced autophagy following DNA mismatch repair processing." Cell research, vol. 20, no. 6, 2010, pp. 665-75.

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Kunos CA, Waggoner S, von Gruenigen V, Eldermire E, Pink J, Dowlati A, Kinsella TJ. "Phase I trial of pelvic radiation, weekly cisplatin, and 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) for locally advanced cervical cancer." Clin Cancer Res , vol. 16, no. 4, 2010, pp. 1298-306.

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Seo Y, Kinsella TJ. "Postresection CA 19-9 value as a prognostic factor: in response to the letter by Kilickap and Arslan." American Journal of Clinical Oncology, vol. 33, no. 1, 2010, pp. 107.

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Kunos CA, Radivoyevitch T, Pink J, Chiu SM, Stefan T, Jacobberger J, Kinsella TJ. "Ribonucleotide reductase inhibition enhances chemoradiosensitivity of human cervical cancers." Radiation Research, vol. 174, no. 5, 2010, pp. 574-81.

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Kinsella TJ. "Coordination of DNA mismatch repair and base excision repair processing of chemotherapy and radiation damage for targeting resistant cancers." Clin Cancer Res , vol. 15, no. 6, 2009, pp. 1853-9.

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Yan T, Seo Y, Kinsella TJ. "Differential cellular responses to prolonged LDR-IR in MLH1-proficient and MLH1-deficient colorectal cancer HCT116 cells." Clin Cancer Res , vol. 15, no. 22, 2009, pp. 6912-20.

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Seo Y, Kinsella TJ. "Essential role of DNA base excision repair on survival in an acidic tumor microenvironment." Cancer Research, vol. 69, no. 18, 2009, pp. 7285-93.

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Kunos CA, Chiu SM, Pink J, Kinsella TJ. "Modulating radiation resistance by inhibiting ribonucleotide reductase in cancers with virally or mutationally silenced p53 protein." Radiation Research, vol. 172, no. 6, 2009, pp. 666-76.

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Aziz MA, Schupp JE, Kinsella TJ. "Modulation of the activity of methyl binding domain protein 4 (MBD4/MED1) while processing iododeoxyuridine generated DNA mispairs." Cancer Biology & Therapy, vol. 34, no. 4, 2009, pp. 853-7.

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Seo Y, Kinsella MT, Reynolds HL, Chipman G, Remick SC, Kinsella TJ. "Outcomes of chemoradiotherapy with 5-Fluorouracil and mitomycin C for anal cancer in immunocompetent versus immunodeficient patients." International Journal of Radiation Oncology*Biology*Physics, vol. 75, no. 1, 2009, pp. 143-9.

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Kinsella TJ. "Understanding DNA damage response and DNA repair pathways: applications to more targeted cancer therapeutics." Seminars in oncology, vol. 36, no. 2 Suppl 1, 2009, pp. S42-51.

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Williams CP, Reynolds HL, Delaney CP, Champagne B, Obias V, Joh YG, Merlino J, Kinsella TJ. "Clinical results of intraoperative radiation therapy for patients with locally recurrent and advanced tumors having colorectal involvement." The American Journal of Surgery, vol. 195, no. 3, 2008, pp. 405-9.

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Kunos CA, Dobbins DC, Kulasekere R, Latimer B, Kinsella TJ. "Comparison of helical tomotherapy versus conventional radiation to deliver craniospinal radiation." Technology in Cancer Research and Treatment, vol. 7, no. 3, 2008, pp. 227-33.

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Messick C, Hardacre JM, McGee MF, Siegel CT, Stellato TA, Sanabria JR, Kinsella TJ, Schulak JA. "Early experience with intraoperative radiotherapy in patients with resected pancreatic adenocarcinoma." The American Journal of Surgery, vol. 195, no. 3, 2008, pp. 308-11; discussion 312.

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Zagar TM, Triche TJ, Kinsella TJ. "Extraosseous Ewing's sarcoma: 25 years later." Journal of Clinical Oncology, vol. 26, no. 26, 2008, pp. 4230-2.

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Small W Jr, Berlin J, Freedman GM, Lawrence T, Talamonti MS, Mulcahy MF, Chakravarthy AB, Konski AA, Zalupski MM, Philip PA, Kinsella TJ, Merchant NB, Hoffman JP, Benson AB, Nicol S, Xu RM, Gill JF, McGinn CJ. "Full-dose gemcitabine with concurrent radiation therapy in patients with nonmetastatic pancreatic cancer: a multicenter phase II trial." Journal of Clinical Oncology, vol. 26, no. 6, 2008, pp. 942-7.

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Zeng X, Kinsella TJ. "Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy." Cancer Research, vol. 68, no. 7, 2008, pp. 2384-90.

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Abbas R, Willis J, Kinsella T, Siegel C, Sanabria J. "Primary squamous cell carcinoma of the main hepatic bile duct." Canadian journal of surgery. Journal canadien de chirurgie, vol. 51, no. 4, 2008, pp. E85-6.

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Zagar TM, Shenk RR, Kim JA, Harpp D, Kunos CA, Abdul-Karim FW, Chen WC, Seo Y, Kinsella TJ. "Radiation therapy in addition to gross total resection of retroperitoneal sarcoma results in prolonged survival: results from a single institutional study." Journal of oncology, vol. 2008, 2008, pp. 824036.

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Kinsella TJ, Seo Y, Willis J, Stellato TA, Siegel CT, Harpp D, Willson JK, Gibbons J, Sanabria JR, Hardacre JM, Schulak JP. "The impact of resection margin status and postoperative CA19-9 levels on survival and patterns of recurrence after postoperative high-dose radiotherapy with 5-FU-based concurrent chemotherapy for resectable pancreatic cancer." American Journal of Clinical Oncology, vol. 31, no. 5, 2008, pp. 446-53.

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Kinsella TJ, Kinsella MT, Hong S, Johnson JP, Burback B, Tosca PJ. "Toxicology and pharmacokinetic study of orally administered 5-iodo-2-pyrimidinone-2'deoxyribose (IPdR) x 28 days in Fischer-344 rats: impact on the initial clinical phase I trial design of IPdR-mediated radiosensitization." Cancer chemotherapy and pharmacology, vol. 61, no. 2, 2008, pp. 323-34.

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Kinsella TJ. "Update on radiosensitization by halogenated thymidine analogs-molecular mechanisms of drug processing and cell death signaling: implications for future clinical trials." Cancer Biology & Therapy, vol. 7, no. 10, 2008, pp. 1567-9.

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Kinsella TJ, Kinsella MT, Seo Y, Berk G. "5-iodo-2-pyrimidinone-2'-deoxyribose-mediated cytotoxicity and radiosensitization in U87 human glioblastoma xenografts." International Journal of Radiation Oncology*Biology*Physics, vol. 69, no. 4, 2007, pp. 1254-61.

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Zeng X, Kinsella TJ. "A novel role for DNA mismatch repair and the autophagic processing of chemotherapy drugs in human tumor cells." Autophagy, vol. 3, no. 4, 2007, pp. 368-70.

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Krishnamurthi SS, Seo Y, Kinsella TJ. "Adjuvant therapy for rectal cancer." Clinics in colon and rectal surgery, vol. 20, no. 3, 2007, pp. 167-81.

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Yamane K, Schupp JE, Kinsella TJ. "BRCA1 activates a G2-M cell cycle checkpoint following 6-thioguanine-induced DNA mismatch damage." Cancer Research, vol. 67, no. 13, 2007, pp. 6286-92.

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Zeng X, Yan T, Schupp JE, Seo Y, Kinsella TJ. "DNA mismatch repair initiates 6-thioguanine--induced autophagy through p53 activation in human tumor cells." Clin Cancer Res , vol. 13, no. 4, 2007, pp. 1315-21.

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Gurkan E, Schupp JE, Aziz MA, Kinsella TJ, Loparo KA. "Probabilistic modeling of DNA mismatch repair effects on cell cycle dynamics and iododeoxyuridine-DNA incorporation." Cancer Research, vol. 67, no. 22, 2007, pp. 10993-1000.

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Talamonti MS, Small W Jr, Mulcahy MF, Wayne JD, Attaluri V, Colletti LM, Zalupski MM, Hoffman JP, Freedman GM, Kinsella TJ, Philip PA, McGinn CJ. "A multi-institutional phase II trial of preoperative full-dose gemcitabine and concurrent radiation for patients with potentially resectable pancreatic carcinoma." Annals of Surgical Oncology, vol. 13, no. 2, 2006, pp. 150-8.

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Kunos C, Latson L, Overmoyer B, Silverman P, Shenk R, Kinsella T, Lyons J. "Breast conservation surgery achieving>or=2 mm tumor-free margins results in decreased local-regional recurrence rates." The Breast Journal, vol. 12, no. 1, 2006, pp. 28-36.

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Kunos C, Colussi V, Getty P, Kinsella T. "Intraoperative electron radiotherapy for extremity sarcomas does not increase acute or late morbidity." Clinical Orthopaedics and Related Research®, vol. 446, 2006, pp. 247-52.

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Yan T, Seo Y, Schupp JE, Zeng X, Desai AB, Kinsella TJ. "Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence." Molecular Cancer Therapeutics, vol. 5, no. 4, 2006, pp. 893-902.

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Turner DP, Cortellino S, Schupp JE, Caretti E, Loh T, Kinsella TJ, Bellacosa A. "The DNA N-glycosylase MED1 exhibits preference for halogenated pyrimidines and is involved in the cytotoxicity of 5-iododeoxyuridine." Cancer Research, vol. 66, no. 15, 2006, pp. 7686-93.

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Seo Y, Yan T, Schupp JE, Yamane K, Radivoyevitch T, Kinsella TJ. "The interaction between two radiosensitizers: 5-iododeoxyuridine and caffeine." Cancer Research, vol. 66, no. 1, 2006, pp. 490-8.

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Yamane K, Kinsella TJ. "Casein kinase 2 regulates both apoptosis and the cell cycle following DNA damage induced by 6-thioguanine." Clin Cancer Res , vol. 11, no. 6, 2005, pp. 2355-63.

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Yamane K, Kinsella TJ. "CK2 inhibits apoptosis and changes its cellular localization following ionizing radiation." Cancer Research, vol. 65, no. 10, 2005, pp. 4362-7.

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Chvetsov AV, Calvetti D, Sohn JW, Kinsella TJ. "Regularization of inverse planning for intensity-modulated radiotherapy." Medical physics, vol. 32, no. 2, 2005, pp. 501-14.

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Seo Y, Yan T, Schupp JE, Radivoyevitch T, Kinsella TJ. "Schedule-dependent drug effects of oral 5-iodo-2-pyrimidinone-2'-deoxyribose as an in vivo radiosensitizer in U251 human glioblastoma xenografts." Clin Cancer Res , vol. 11, no. 20, 2005, pp. 7499-507.

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Yan T, Desai AB, Jacobberger JW, Sramkoski RM, Loh T, Kinsella TJ. "CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses." Molecular Cancer Therapeutics, vol. 3, no. 9, 2004, pp. 1147-57.

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Schulz CA, Mehta MP, Badie B, McGinn CJ, Robins HI, Hayes L, Chappell R, Volkman J, Binger K, Arzoomanian R, Simon K, Alberti D, Feierabend C, Tutsch KD, Kunugi KA, Wilding G, Kinsella TJ. "Continuous 28-day iododeoxyuridine infusion and hyperfractionated accelerated radiotherapy for malignant glioma: a phase I clinical study." International Journal of Radiation Oncology*Biology*Physics, vol. 59, no. 4, 2004, pp. 1107-15.

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Seo Y, Yan T, Schupp JE, Colussi V, Taylor KL, Kinsella TJ. "Differential radiosensitization in DNA mismatch repair-proficient and -deficient human colon cancer xenografts with 5-iodo-2-pyrimidinone-2'-deoxyribose." Clin Cancer Res , vol. 10, no. 22, 2004, pp. 7520-8.

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Kunos CA, Resnick MI, Kinsella TJ, Ellis RJ. "Migration of implanted free radioactive seeds for adenocarcinoma of the prostate using a Mick applicator." Brachytherapy, vol. 3, no. 2, 2004, pp. 71-7.

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Yamane K, Taylor K, Kinsella TJ. "Mismatch repair-mediated G2/M arrest by 6-thioguanine involves the ATR-Chk1 pathway." Biochemical and Biophysical Research Communications, vol. 318, no. 1, 2004, pp. 297-302.

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Yamane K, Chen J, Kinsella TJ. "Both DNA topoisomerase II-binding protein 1 and BRCA1 regulate the G2-M cell cycle checkpoint." Cancer Research, vol. 63, no. 12, 2003, pp. 3049-53.

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Yan T, Berry SE, Desai AB, Kinsella TJ. "DNA mismatch repair (MMR) mediates 6-thioguanine genotoxicity by introducing single-strand breaks to signal a G2-M arrest in MMR-proficient RKO cells." Clin Cancer Res , vol. 9, no. 6, 2003, pp. 2327-34.

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Ellis RJ, Vertocnik A, Kim E, Zhou H, Young B, Sodee B, Fu P, Beddar S, Colussi V, Spirnak JP, Dinchman KH, Resnick M, Kinsella TJ. "Four-year biochemical outcome after radioimmunoguided transperineal brachytherapy for patients with prostate adenocarcinoma." International Journal of Radiation Oncology*Biology*Physics, vol. 57, no. 2, 2003, pp. 362-70.

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Taverna P, Hwang HS, Schupp JE, Radivoyevitch T, Session NN, Reddy G, Zarling DA, Kinsella TJ. "Inhibition of base excision repair potentiates iododeoxyuridine-induced cytotoxicity and radiosensitization." Cancer Research, vol. 63, no. 4, 2003, pp. 838-46.

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Ellis RJ, Kim E, Kinsella TJ, Eisenberg BL. "Intraoperative radiotherapy in the multimodality approach to bone and soft tissue cancers." Surgical oncology clinics of North America, vol. 12, no. 4, 2003, pp. 1015-29.

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Sindelar WF, Kinsella TJ. "Normal tissue tolerance to intraoperative radiotherapy." Surgical oncology clinics of North America, vol. 12, no. 4, 2003, pp. 925-42.

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Kuo ML, Hwang HS, Sosnay PR, Kunugi KA, Kinsella TJ. "Overexpression of the R2 subunit of ribonucleotide reductase in human nasopharyngeal cancer cells reduces radiosensitivity." Cancer journal (Sudbury, Mass.), vol. 9, no. 4, 2003, pp. 277-85.

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Wu QR, Wessels BW, Einstein DB, Maciunas RJ, Kim EY, Kinsella TJ. "Quality of coverage: conformity measures for stereotactic radiosurgery." Journal of applied clinical medical physics / American College of Medical Physics, vol. 4, no. 4, 2003, pp. 374-81.

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Wu QJ, Chankong V, Jitprapaikulsarn S, Wessels BW, Einstein DB, Mathayomchan B, Kinsella TJ. "Real-time inverse planning for Gamma Knife radiosurgery." Medical physics, vol. 30, no. 11, 2003, pp. 2988-95.

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Berry SE, Loh T, Yan T, Kinsella TJ. "Role of MutSalpha in the recognition of iododeoxyuridine in DNA." Cancer Research, vol. 63, no. 17, 2003, pp. 5490-5.

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Leskov KS, Klokov DY, Li J, Kinsella TJ, Boothman DA. "Synthesis and functional analyses of nuclear clusterin, a cell death protein." Journal of Biological Chemistry, vol. 278, no. 13, 2003, pp. 11590-600.

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Domanovic MA, Ouzidane M, Ellis RJ, Kinsella TJ, Beddar AS. "Using intraoperative radiation therapy--a case study." AORN journal, vol. 77, no. 2, 2003, pp. 412-7.

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Beddar AS, Kubu ML, Domanovic MA, Ellis RJ, Kinsella TJ, Sibata CH. "A new approach to intraoperative radiation therapy." AORN journal, vol. 74, no. 4, 2001, pp. 500-5.

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Colussi VC, Beddar AS, Kinsella TJ, Sibata CH. "In vivo dosimetry using a single diode for megavoltage photon beam radiotherapy: implementation and response characterization." Journal of applied clinical medical physics / American College of Medical Physics, vol. 2, no. 4, 2001, pp. 210-8.

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Yan T, Schupp JE, Hwang HS, Wagner MW, Berry SE, Strickfaden S, Veigl ML, Sedwick WD, Boothman DA, Kinsella TJ. "Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation." Cancer Research, vol. 61, no. 22, 2001, pp. 8290-7.

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Taverna P, Liu L, Hwang HS, Hanson AJ, Kinsella TJ, Gerson SL. "Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells." Mutation research, vol. 485, no. 4, 2001, pp. 269-81.

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Beddar AS, Domanovic MA, Kubu ML, Ellis RJ, Sibata CH, Kinsella TJ. "Mobile linear accelerators for intraoperative radiation therapy." AORN journal, vol. 74, no. 5, 2001, pp. 700-5.

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Sibata CH, Colussi VC, Oleinick NL, Kinsella TJ. "Photodynamic therapy in oncology." Expert opinion on pharmacotherapy, vol. 2, no. 6, 2001, pp. 917-27.

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Ellis RJ, Kim EY, Conant R, Sodee DB, Spirnak JP, Dinchman KH, Beddar S, Wessels B, Resnick MI, Kinsella TJ. "Radioimmunoguided imaging of prostate cancer foci with histopathological correlation." International Journal of Radiation Oncology*Biology*Physics, vol. 49, no. 5, 2001, pp. 1281-6.

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Meyers M, Wagner MW, Hwang HS, Kinsella TJ, Boothman DA. "Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses." Cancer Research, vol. 61, no. 13, 2001, pp. 5193-201.

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Berry SE, Kinsella TJ. "Targeting DNA mismatch repair for radiosensitization." Seminars in radiation oncology, vol. 11, no. 4, 2001, pp. 300-15.

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Leskov KS, Criswell T, Antonio S, Li J, Yang CR, Kinsella TJ, Boothman DA. "When X-ray-inducible proteins meet DNA double strand break repair." Seminars in radiation oncology, vol. 11, no. 4, 2001, pp. 352-72.

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Ellis RJ, Nag S, Kinsella TJ. "Alternative techniques of intraoperative radiotherapy." European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, vol. 26 Suppl A, 2000, pp. S25-7.

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McGinn CJ, Pestalozzi BC, Drake JC, Glennon MC, Kunugi K, Otterson G, Allegra CJ, Johnston PG, Kinsella TJ. "Cell cycle regulation of the G0/G1 transition in 5-fluorouracil-sensitive and -resistant human colon cancer cell lines." Cancer journal (Sudbury, Mass.), vol. 6, no. 4, 2000, pp. 234-42.

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Miyamoto S, Huang TT, Wuerzberger-Davis S, Bornmann WG, Pink JJ, Tagliarino C, Kinsella TJ, Boothman DA. "Cellular and molecular responses to topoisomerase I poisons. Exploiting synergy for improved radiotherapy." Annals of the New York Academy of Sciences, vol. 922, 2000, pp. 274-92.

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Ellis RJ, Sodee DB, Spirnak JP, Dinchman KH, O'Leary AW, Samuels MA, Resnick MI, Kinsella TJ. "Feasibility and acute toxicities of radioimmunoguided prostate brachytherapy." International Journal of Radiation Oncology*Biology*Physics, vol. 48, no. 3, 2000, pp. 683-7.

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Yang CR, Leskov K, Hosley-Eberlein K, Criswell T, Pink JJ, Kinsella TJ, Boothman DA. "Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death." Proceedings of the National Academy of Sciences, vol. 97, no. 11, 2000, pp. 5907-12.

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Sibata CH, Colussi VC, Oleinick NL, Kinsella TJ. "Photodynamic therapy: a new concept in medical treatment." Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.], vol. 33, no. 8, 2000, pp. 869-80.

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Kinsella TJ, Schupp JE, Davis TW, Berry SE, Hwang HS, Warren K, Balis F, Barnett J, Sands H. "Preclinical study of the systemic toxicity and pharmacokinetics of 5-iodo-2-deoxypyrimidinone-2'-deoxyribose as a radiosensitizing prodrug in two, non-rodent animal species: implications for phase I study design." Clin Cancer Res , vol. 6, no. 9, 2000, pp. 3670-9.

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Kinsella TJ, Vielhuber KA, Kunugi KA, Schupp J, Davis TW, Sands H. "Preclinical toxicity and efficacy study of a 14-day schedule of oral 5-iodo-2-pyrimidinone-2'-deoxyribose as a prodrug for 5-iodo-2'-deoxyuridine radiosensitization in U251 human glioblastoma xenografts." Clin Cancer Res , vol. 6, no. 4, 2000, pp. 1468-75.

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Hwang HS, Davis TW, Houghton JA, Kinsella TJ. "Radiosensitivity of thymidylate synthase-deficient human tumor cells is affected by progression through the G1 restriction point into S-phase: implications for fluoropyrimidine radiosensitization." Cancer Research, vol. 60, no. 1, 2000, pp. 92-100.

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Berry SE, Davis TW, Schupp JE, Hwang HS, de Wind N, Kinsella TJ. "Selective radiosensitization of drug-resistant MutS homologue-2 (MSH2) mismatch repair-deficient cells by halogenated thymidine (dThd) analogues: Msh2 mediates dThd analogue DNA levels and the differential cytotoxicity and cell cycle effects of the dThd analogues and 6-thioguanine." Cancer Research, vol. 60, no. 20, 2000, pp. 5773-80.

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Mineishi S, Longo WL, Atkinson ME, Smith EP, Hamielec M, Wiersma SR, Kinsella TJ, Schuening FG. "Addition of high-dose Ara-C to the BMT conditioning regimen reduces leukemia relapse without an increase in toxicity." Bone marrow transplantation, vol. 23, no. 12, 1999, pp. 1217-22.

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Yang CR, Yeh S, Leskov K, Odegaard E, Hsu HL, Chang C, Kinsella TJ, Chen DJ, Boothman DA. "Isolation of Ku70-binding proteins (KUBs)." Nucleic acids research, vol. 27, no. 10, 1999, pp. 2165-74.

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Sindelar WF, Kinsella TJ. "Studies of intraoperative radiotherapy in carcinoma of the pancreas." Annals of Oncology, vol. 10 Suppl 4, 1999, pp. 226-30.

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Berry SE, Garces C, Hwang HS, Kunugi K, Meyers M, Davis TW, Boothman DA, Kinsella TJ. "The mismatch repair protein, hMLH1, mediates 5-substituted halogenated thymidine analogue cytotoxicity, DNA incorporation, and radiosensitization in human colon cancer cells." Cancer Research, vol. 59, no. 8, 1999, pp. 1840-5.

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Paliwal BR, Ritter MA, McNutt TR, Mackie TR, Thomadsen BR, Purdy JA, Kinsella TJ. "A solid water pelvic and prostate phantom for imaging, volume rendering, treatment planning, and dosimetry for an RTOG multi-institutional, 3-D dose escalation study. Radiation Therapy Oncology Group." International Journal of Radiation Oncology*Biology*Physics, vol. 42, no. 1, 1998, pp. 205-11.

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Bullen R, Larson PO, Landeck AE, Nychay S, Snow SN, Hazen P, Kinsella T, Lamond J. "Angiosarcoma of the head and neck managed by a combination of multiple biopsies to determine tumor margin and radiation therapy. Report of three cases and review of the literature." Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], vol. 24, no. 10, 1998, pp. 1105-10.

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Davis TW, Wilson-Van Patten C, Meyers M, Kunugi KA, Cuthill S, Reznikoff C, Garces C, Boland CR, Kinsella TJ, Fishel R, Boothman DA. "Defective expression of the DNA mismatch repair protein, MLH1, alters G2-M cell cycle checkpoint arrest following ionizing radiation." Cancer Research, vol. 58, no. 4, 1998, pp. 767-78.

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Kuo ML, Kinsella TJ. "Expression of ribonucleotide reductase after ionizing radiation in human cervical carcinoma cells." Cancer Research, vol. 58, no. 10, 1998, pp. 2245-52.

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Kinsella TJ, Kunugi KA, Vielhuber KA, Potter DM, Fitzsimmons ME, Collins JM. "Preclinical evaluation of 5-iodo-2-pyrimidinone-2'-deoxyribose as a prodrug for 5-iodo-2'-deoxyuridine-mediated radiosensitization in mouse and human tissues." Clin Cancer Res , vol. 4, no. 1, 1998, pp. 99-109.

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Mehta M, Noyes W, Craig B, Lamond J, Auchter R, French M, Johnson M, Levin A, Badie B, Robbins I, Kinsella T. "A cost-effectiveness and cost-utility analysis of radiosurgery vs. resection for single-brain metastases." International Journal of Radiation Oncology*Biology*Physics, vol. 39, no. 2, 1997, pp. 445-54.

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Boothman DA, Burrows HL, Yang CR, Davis TW, Wuerzberger SM, Planchon SM, Odegaard E, Lewis JE, Pink J, Meyers M, Patten CW, Sharda N, Kinsella TJ. "Damage-sensing mechanisms in human cells after ionizing radiation." STEM CELLS, vol. 15 Suppl 2, 1997, pp. 27-42.

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Tannehill SP, Mehta MP, Larson M, Storer B, Pellet J, Kinsella TJ, Schiller JH. "Effect of amifostine on toxicities associated with sequential chemotherapy and radiation therapy for unresectable non-small-cell lung cancer: results of a phase II trial." Journal of Clinical Oncology, vol. 15, no. 8, 1997, pp. 2850-7.

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Kuo ML, Kunugi KA, Lindstrom MJ, Kinsella TJ. "The interaction of hydroxyurea and ionizing radiation in human cervical carcinoma cells." The cancer journal from Scientific American, vol. 3, no. 3, 1997, pp. 163-73.

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Mehta MP, Kinsella TJ. "What's new in radiation oncology." Wisconsin medical journal, vol. 96, no. 4, 1997, pp. 42-9.

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Auchter RM, Lamond JP, Alexander E, Buatti JM, Chappell R, Friedman WA, Kinsella TJ, Levin AB, Noyes WR, Schultz CJ, Loeffler JS, Mehta MP. "A multiinstitutional outcome and prognostic factor analysis of radiosurgery for resectable single brain metastasis." International Journal of Radiation Oncology*Biology*Physics, vol. 35, no. 1, 1996, pp. 27-35.

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Sharda NN, Kinsella TJ, Ritter MA. "Adjuvant radiation versus observation: a cost analysis of alternate management schemes in early-stage testicular seminoma." Journal of Clinical Oncology, vol. 14, no. 11, 1996, pp. 2933-9.

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Kinsella TJ. "An approach to the radiosensitization of human tumors." The cancer journal from Scientific American, vol. 2, no. 4, 1996, pp. 184-93.

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Lamond JP, Wang M, Kinsella TJ, Boothman DA. "Concentration and timing dependence of lethality enhancement between topotecan, a topoisomerase I inhibitor, and ionizing radiation." International Journal of Radiation Oncology*Biology*Physics, vol. 36, no. 2, 1996, pp. 361-8.

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Kinsella TJ. "Correspondence re: J.A. Knol et al., Incorporation of 5-bromo-2-deoxyuridine into colorectal liver metastases and liver in patients receiving a 7-day hepatic arterial infusion. Cancer Res., 55: 3687-3691, 1995." Cancer Research, vol. 56, no. 11, 1996, pp. 2677-8.

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Kinsella TJ, Glennon MC, Kunugi KA, Lindstrom MJ. "In vivo modulation of iododeoxyuridine metabolism and incorporation into cellular DNA by 5'-amino-5'-deoxythymidine in normal mouse tissues and two human colon cancer xenografts." Clin Cancer Res , vol. 2, no. 6, 1996, pp. 981-9.

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Kinsella TJ, Sindelar WF. "Intraoperative radiotherapy for pancreatic carcinoma. Experimental and clinical studies." Cancer, vol. 78, no. 3 Suppl, 1996, pp. 598-604.

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McGinn CJ, Kunugi KA, Tutsch KD, Feierabend C, Alberti D, Lindstrom MJ, Wilding G, Arzoomanian RZ, Kinsella TJ. "Leucovorin modulation of 5-iododeoxyuridine radiosensitization: a phase I study." Clin Cancer Res , vol. 2, no. 8, 1996, pp. 1299-305.

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Mehta MP, Kinsella TJ, Harari PM, Ritter MA, Mahler PA, Steeves RA, Stitt JA, Petereit DG. "Manpower issues and training program directions in radiation oncology." International Journal of Radiation Oncology*Biology*Physics, vol. 34, no. 4, 1996, pp. 970.

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Lamond JP, Wang M, Kinsella TJ, Boothman DA. "Radiation lethality enhancement with 9-aminocamptothecin: comparison to other topoisomerase I inhibitors." International Journal of Radiation Oncology*Biology*Physics, vol. 36, no. 2, 1996, pp. 369-76.

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Noyes WR, Rodriguez R, Knechtle SJ, Pirsch JD, Sollinger HW, D'Alessandro AM, Chappell R, Belzer FO, Kinsella TJ. "Radiation therapy for renal transplant rejection refractory to pulse steroids and OKT3." International Journal of Radiation Oncology*Biology*Physics, vol. 34, no. 5, 1996, pp. 1055-9.

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Urtasun RC, Kinsella TJ, Farnan N, DelRowe JD, Lester SG, Fulton DS. "Survival improvement in anaplastic astrocytoma, combining external radiation with halogenated pyrimidines: final report of RTOG 86-12, Phase I-II study." International Journal of Radiation Oncology*Biology*Physics, vol. 36, no. 5, 1996, pp. 1163-7.

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Harari PM, Kinsella TJ. "Advances in radiation therapy for head and neck cancer." Current opinion in oncology, vol. 7, no. 3, 1995, pp. 248-54.

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Johnstone PA, DeLuca AM, Bacher JD, Hampshire VA, Terrill RE, Anderson WJ, Kinsella TJ, Sindelar WF. "Clinical toxicity of peripheral nerve to intraoperative radiotherapy in a canine model." International Journal of Radiation Oncology*Biology*Physics, vol. 32, no. 4, 1995, pp. 1031-4.

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Hoekstra HJ, Sindelar WF, Szabo BG, Kinsella TJ. "Hemipelvectomy and intraoperative radiotherapy for bone and soft tissue sarcomas of the pelvic girdle." Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, vol. 37, no. 2, 1995, pp. 160-3.

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Noyes WR, Peters NE, Thomadsen BR, Fowler JF, Buchler DA, Stitt JA, Kinsella TJ. "Impact of "optimized" treatment planning for tandem and ring, and tandem and ovoids, using high dose rate brachytherapy for cervical cancer." International Journal of Radiation Oncology*Biology*Physics, vol. 31, no. 1, 1995, pp. 79-86.

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Pestalozzi BC, McGinn CJ, Kinsella TJ, Drake JC, Glennon MC, Allegra CJ, Johnston PG. "Increased thymidylate synthase protein levels are principally associated with proliferation but not cell cycle phase in asynchronous human cancer cells." Br J Cancer, vol. 71, no. 6, 1995, pp. 1151-7.

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Schultz CJ, Gaffney DK, Lindstrom MJ, Kinsella TJ. "Iododeoxyuridine radiosensitization of human glioblastoma cells exposed to acute and chronic gamma irradiation: mechanistic implications and clinical relevance." The cancer journal from Scientific American, vol. 1, no. 2, 1995, pp. 151-61.

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Terrier P, Henry-Amar M, Triche TJ, Horowitz ME, Terrier-Lacombe MJ, Miser JS, Kinsella TJ, Contesso G, Llombart-Bosch A. "Is neuro-ectodermal differentiation of Ewing's sarcoma of bone associated with an unfavourable prognosis?." European journal of cancer (Oxford, England : 1990), vol. 31A, no. 3, 1995, pp. 307-14.

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Noyes WR, Bastin K, Edwards SA, Buchler DA, Stitt JA, Thomadsen BR, Fowler JF, Kinsella TJ. "Postoperative vaginal cuff irradiation using high dose rate remote afterloading: a phase II clinical protocol." International Journal of Radiation Oncology*Biology*Physics, vol. 32, no. 5, 1995, pp. 1439-43.

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Harari PM, O'Connor NJ, Fiore MC, Kinsella TJ. "Radiation oncologists can assist head and neck cancer patients with smoking cessation." International Journal of Radiation Oncology*Biology*Physics, vol. 31, no. 3, 1995, pp. 645-9.

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Sarkaria JN, Mehta MP, Loeffler JS, Buatti JM, Chappell RJ, Levin AB, Alexander E 3rd, Friedman WA, Kinsella TJ. "Radiosurgery in the initial management of malignant gliomas: survival comparison with the RTOG recursive partitioning analysis. Radiation Therapy Oncology Group." International Journal of Radiation Oncology*Biology*Physics, vol. 32, no. 4, 1995, pp. 931-41.

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Petereit DG, Sarkaria JN, Chappell R, Fowler JF, Hartmann TJ, Kinsella TJ, Stitt JA, Thomadsen BR, Buchler DA. "The adverse effect of treatment prolongation in cervical carcinoma." International Journal of Radiation Oncology*Biology*Physics, vol. 32, no. 5, 1995, pp. 1301-7.

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Kuo ML, Kunugi KA, Lindstrom MJ, Kinsella TJ. "The interaction of hydroxyurea and iododeoxyuridine on the radiosensitivity of human bladder cancer cells." Cancer Research, vol. 55, no. 13, 1995, pp. 2800-5.

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Sarkaria JN, Petereit DG, Stitt JA, Hartman T, Chappell R, Thomadsen BR, Buchler DA, Fowler JF, Kinsella TJ. "A comparison of the efficacy and complication rates of low dose-rate versus high dose-rate brachytherapy in the treatment of uterine cervical carcinoma." International Journal of Radiation Oncology*Biology*Physics, vol. 30, no. 1, 1994, pp. 75-82; discussion 247.

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Kinsella TJ, Kunugi KA, Vielhuber KA, McCulloch W, Liu SH, Cheng YC. "An in vivo comparison of oral 5-iodo-2'-deoxyuridine and 5-iodo-2-pyrimidinone-2'-deoxyribose toxicity, pharmacokinetics, and DNA incorporation in athymic mouse tissues and the human colon cancer xenograft, HCT-116." Cancer Research, vol. 54, no. 10, 1994, pp. 2695-700.

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Petereit DG, Harari PM, Contreras L, Pickart MA, Verma AK, Gerner EW, Kinsella TJ. "Combining polyamine depletion with radiation therapy for rapidly dividing head and neck tumors: strategies for improved locoregional control." International Journal of Radiation Oncology*Biology*Physics, vol. 28, no. 4, 1994, pp. 891-8.

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Johnstone PA, Sprague M, DeLuca AM, Bacher JD, Hampshire VA, Terrill RE, Kinsella TJ, Sindelar WF. "Effects of intraoperative radiotherapy on vascular grafts in a canine model." International Journal of Radiation Oncology*Biology*Physics, vol. 29, no. 5, 1994, pp. 1015-25.

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Johnstone PA, Sindelar WF, Kinsella TJ. "Experimental and clinical studies of intraoperative radiation therapy." Current problems in cancer, vol. 18, no. 5, 1994, pp. 249-90.

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Chi KH, Kunugi KA, Kinsella TJ. "Iododeoxyuridine chemosensitization of cis-diamminedichloroplatinum(II) in human bladder cancer cells." Cancer Research, vol. 54, no. 10, 1994, pp. 2701-6.

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Rodriguez R, Ritter MA, Fowler JF, Kinsella TJ. "Kinetics of cell labeling and thymidine replacement after continuous infusion of halogenated pyrimidines in vivo." International Journal of Radiation Oncology*Biology*Physics, vol. 29, no. 1, 1994, pp. 105-13.

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Sindelar WF, Tepper JE, Kinsella TJ, Barnes M, DeLuca AM, Terrill R, Matthews D, Anderson WJ, Bollinger BK, Johnstone PA. "Late effects of intraoperative radiation therapy on retroperitoneal tissues, intestine, and bile duct in a large animal model." International Journal of Radiation Oncology*Biology*Physics, vol. 29, no. 4, 1994, pp. 781-8.

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Sullivan FJ, Herscher LL, Cook JA, Smith J, Steinberg SM, Epstein AH, Oldfield EH, Goffman TE, Kinsella TJ, Mitchell JB. "National Cancer Institute (phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: results in anaplastic astrocytoma." International Journal of Radiation Oncology*Biology*Physics, vol. 30, no. 3, 1994, pp. 583-90.

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Petereit DG, Fowler JF, Kinsella TJ. "Optimizing the dose rate and technique in cervical carcinoma--balancing cases versus complications." International Journal of Radiation Oncology*Biology*Physics, vol. 29, no. 5, 1994, pp. 1195-7.

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McGinn CJ, Miller EM, Lindstrom MJ, Kunugi KA, Johnston PG, Kinsella TJ. "The role of cell cycle redistribution in radiosensitization: implications regarding the mechanism of fluorodeoxyuridine radiosensitization." International Journal of Radiation Oncology*Biology*Physics, vol. 30, no. 4, 1994, pp. 851-9.

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DeLuca AM, Johnstone PA, Ollayos CW, Bacher JD, Terrill RE, Kinsella TJ, Sindelar WF. "Tolerance of the bladder to intraoperative radiation in a canine model: a five-year follow-up." International Journal of Radiation Oncology*Biology*Physics, vol. 30, no. 2, 1994, pp. 339-45.

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Ritter MA, Albrechtson JL, Kim YJ, Kinsella TJ. "Tumor cell kinetics in mixed populations." Cytometry, vol. 16, no. 2, 1994, pp. 118-28.

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Ritter MA, Fowler JF, Kim YJ, Gilchrist KW, Morrissey LW, Kinsella TJ. "Tumor cell kinetics using two labels and flow cytometry." Cytometry, vol. 16, no. 1, 1994, pp. 49-58.

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Petereit DG, Mehta MP, Buchler DA, Kinsella TJ. "A retrospective review of nodal treatment for vulvar cancer." American Journal of Clinical Oncology, vol. 16, no. 1, 1993, pp. 38-42.

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Mehta MP, Kinsella TJ. "Cavernous sinus cranial neuropathies: is there a dose-response relationship following radiosurgery?." International Journal of Radiation Oncology*Biology*Physics, vol. 27, no. 2, 1993, pp. 477-80.

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McGinn CJ, Harari PM, Fowler JF, Ford CN, Pyle GM, Kinsella TJ. "Dose intensification in curative head and neck cancer radiotherapy--linear quadratic analysis and preliminary assessment of clinical results." International Journal of Radiation Oncology*Biology*Physics, vol. 27, no. 2, 1993, pp. 363-9.

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Kunugi KA, Lindstrom MJ, Kinsella TJ. "Effects of bleomycin with iododeoxyuridine, 5'-amino-5'-deoxythymidine, and radiation in a human bladder cancer cell line." Radiation Research, vol. 135, no. 2, 1993, pp. 262-8.

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Lindstrom MJ, Kunugi KA, Kinsella TJ. "Global comparison of radiation and chemotherapy dose-response curves with a test for interaction." Radiation Research, vol. 135, no. 2, 1993, pp. 269-77.

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Petereit DG, Mehta MP, Buchler DA, Kinsella TJ. "Inguinofemoral radiation of N0,N1 vulvar cancer may be equivalent to lymphadenectomy if proper radiation technique is used." International Journal of Radiation Oncology*Biology*Physics, vol. 27, no. 4, 1993, pp. 963-7.

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Sindelar WF, Kinsella TJ, Chen PW, DeLaney TF, Tepper JE, Rosenberg SA, Glatstein E. "Intraoperative radiotherapy in retroperitoneal sarcomas. Final results of a prospective, randomized, clinical trial." Archives of surgery (Chicago, Ill. : 1960), vol. 128, no. 4, 1993, pp. 402-10.

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Urtasun RC, Cosmatos D, DelRowe J, Kinsella TJ, Lester S, Wasserman T, Fulton DS. "Iododeoxyuridine (IUdR) combined with radiation in the treatment of malignant glioma: a comparison of short versus long intravenous dose schedules (RTOG 86-12)." International Journal of Radiation Oncology*Biology*Physics, vol. 27, no. 2, 1993, pp. 207-14.

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Mehta MP, Petereit D, Turski P, Gehring M, Levin A, Kinsella T. "Magnetic resonance angiography: a three-dimensional database for assessing arteriovenous malformations. Technical note." Journal of Neurosurgery, vol. 79, no. 2, 1993, pp. 289-93.

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Harari PM, Contreras L, Pickart MA, Ritter MA, Kinsella TJ. "Modulation of proliferation kinetics in human squamous cell carcinomas of the head and neck." Archives of otolaryngology--head & neck surgery, vol. 119, no. 7, 1993, pp. 738-42.

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Sindelar WF, Kinsella TJ, Tepper JE, DeLaney TF, Maher MM, Smith R, Rosenberg SA, Glatstein E. "Randomized trial of intraoperative radiotherapy in carcinoma of the stomach." The American Journal of Surgery, vol. 165, no. 1, 1993, pp. 178-86; discussion 186-7.

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Bastin K, Buchler D, Stitt J, Shanahan T, Pola Y, Paliwal B, Kinsella T. "Resource utilization. High dose rate versus low dose rate brachytherapy for gynecologic cancer." American Journal of Clinical Oncology, vol. 16, no. 3, 1993, pp. 256-63.

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Kinsella TJ. "Soft tissue sarcoma: combined modality approaches." Frontiers of radiation therapy and oncology, vol. 27, 1993, pp. 186-99.

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Holmes MA, Mackie TR, Sohn W, Reckwerdt PJ, Kinsella TJ, Bielajew AF, Rogers DW. "The application of correlated sampling to the computation of electron beam dose distributions in heterogeneous phantoms using the Monte Carlo method." Physics in Medicine & Biology, vol. 38, no. 6, 1993, pp. 675-88.

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McGinn CJ, Kinsella TJ. "The clinical rationale for S-phase radiosensitization in human tumors." Current problems in cancer, vol. 17, no. 5, 1993, pp. 273-321.

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Bastin KT, Mehta MP, Kinsella TJ. "Thoracic volume radiation sparing following endobronchial brachytherapy: a quantitative analysis." International Journal of Radiation Oncology*Biology*Physics, vol. 25, no. 4, 1993, pp. 703-7.

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Mackie TR, Holmes T, Swerdloff S, Reckwerdt P, Deasy JO, Yang J, Paliwal B, Kinsella T. "Tomotherapy: a new concept for the delivery of dynamic conformal radiotherapy." Medical physics, vol. 20, no. 6, 1993, pp. 1709-19.

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Horowitz ME, Kinsella TJ, Wexler LH, Belasco J, Triche T, Tsokos M, Steinberg SM, McClure L, Longo DL, Steis RG. "Total-body irradiation and autologous bone marrow transplant in the treatment of high-risk Ewing's sarcoma and rhabdomyosarcoma." Journal of Clinical Oncology, vol. 11, no. 10, 1993, pp. 1911-8.

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Petereit D, Mehta M, Turski P, Levin A, Strother C, Mistretta C, Mackie R, Gehring M, Kubsad S, Kinsella T. "Treatment of arteriovenous malformations with stereotactic radiosurgery employing both magnetic resonance angiography and standard angiography as a database." International Journal of Radiation Oncology*Biology*Physics, vol. 25, no. 2, 1993, pp. 309-13.

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Mehta MP, Rozental JM, Levin AB, Mackie TR, Kubsad SS, Gehring MA, Kinsella TJ. "Defining the role of radiosurgery in the management of brain metastases." International Journal of Radiation Oncology*Biology*Physics, vol. 24, no. 4, 1992, pp. 619-25.

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Stitt JA, Fowler JF, Thomadsen BR, Buchler DA, Paliwal BP, Kinsella TJ. "High dose rate intracavitary brachytherapy for carcinoma of the cervix: the Madison system: I. Clinical and radiobiological considerations." International Journal of Radiation Oncology*Biology*Physics, vol. 24, no. 2, 1992, pp. 335-48.

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Thomadsen BR, Shahabi S, Stitt JA, Buchler DA, Fowler JF, Paliwal BR, Kinsella TJ. "High dose rate intracavitary brachytherapy for carcinoma of the cervix: the Madison system: II. Procedural and physical considerations." International Journal of Radiation Oncology*Biology*Physics, vol. 24, no. 2, 1992, pp. 349-57.

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Miller EM, Fowler JF, Kinsella TJ. "Linear-quadratic analysis of radiosensitization by halogenated pyrimidines. I. Radiosensitization of human colon cancer cells by iododeoxyuridine." Radiation Research, vol. 131, no. 1, 1992, pp. 81-9.

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Miller EM, Fowler JF, Kinsella TJ. "Linear-quadratic analysis of radiosensitization by halogenated pyrimidines. II. Radiosensitization of human colon cancer cells by bromodeoxyuridine." Radiation Research, vol. 131, no. 1, 1992, pp. 90-7.

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Tochner ZA, Pass HI, Sindelar WF, DeLuca AM, Grisell DL, Bacher JD, Kinsella TJ. "Long term tolerance of thoracic organs to intraoperative radiotherapy." International Journal of Radiation Oncology*Biology*Physics, vol. 22, no. 1, 1992, pp. 65-9.

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Kunugi KA, Miller EM, Vazquez-Padua MA, Kinsella TJ. "Low pH does not affect the dose response for 5'-amino-5'-deoxythymidine modulation of IdUrd DNA incorporation and radiosensitization in a human bladder cancer cell line." Radiation Research, vol. 132, no. 2, 1992, pp. 222-7.

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Ritter MA, Messing EM, Shanahan TG, Potts S, Chappell RJ, Kinsella TJ. "Prostate-specific antigen as a predictor of radiotherapy response and patterns of failure in localized prostate cancer." Journal of Clinical Oncology, vol. 10, no. 8, 1992, pp. 1208-17.

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Kinsella TJ. "Radiosensitization and cell kinetics: clinical implications for S-phase-specific radiosensitizers." Seminars in oncology, vol. 19, no. 3 Suppl 9, 1992, pp. 41-7.

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Miller EM, Kinsella TJ. "Radiosensitization by fluorodeoxyuridine: effects of thymidylate synthase inhibition and cell synchronization." Cancer Research, vol. 52, no. 7, 1992, pp. 1687-94.

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Tsokos M, Webber BL, Parham DM, Wesley RA, Miser A, Miser JS, Etcubanas E, Kinsella T, Grayson J, Glatstein E. "Rhabdomyosarcoma. A new classification scheme related to prognosis." Archives of Pathology & Laboratory Medicine, vol. 116, no. 8, 1992, pp. 847-55.

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Mehta M, Petereit D, Chosy L, Harmon M, Fowler J, Shahabi S, Thomadsen B, Kinsella T. "Sequential comparison of low dose rate and hyperfractionated high dose rate endobronchial radiation for malignant airway occlusion." International Journal of Radiation Oncology*Biology*Physics, vol. 23, no. 1, 1992, pp. 133-9.

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Ritter MA, Fowler JF, Kim Y, Lindstrom MJ, Kinsella TJ. "Single biopsy, tumor kinetic analyses: a comparison of methods and an extension to shorter sampling intervals." International Journal of Radiation Oncology*Biology*Physics, vol. 23, no. 4, 1992, pp. 811-20.

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McGinn CJ, Kinsella TJ. "The experimental and clinical rationale for the use of S-phase-specific radiosensitizers to overcome tumor cell repopulation." Seminars in oncology, vol. 19, no. 4 Suppl 11, 1992, pp. 21-8.

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Gehring MA, Mackie TR, Kubsad SS, Paliwal BR, Mehta MP, Kinsella TJ. "A three-dimensional volume visualization package applied to stereotactic radiosurgery treatment planning." International Journal of Radiation Oncology*Biology*Physics, vol. 21, no. 2, 1991, pp. 491-500.

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McGinn CJ, Kinsella TJ. "Combined modality therapy." Current opinion in oncology, vol. 3, no. 6, 1991, pp. 1049-54.

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Rodriguez R, Miller E, Fowler JF, Kinsella TJ. "Continuous infusion of halogenated pyrimidines." International Journal of Radiation Oncology*Biology*Physics, vol. 20, no. 6, 1991, pp. 1380-2.

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Rozental JM, Levine RL, Mehta MP, Kinsella TJ, Levin AB, Algan O, Mendoza M, Hanson JM, Schrader DA, Nickles RJ. "Early changes in tumor metabolism after treatment: the effects of stereotactic radiotherapy." International Journal of Radiation Oncology*Biology*Physics, vol. 20, no. 5, 1991, pp. 1053-60.

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Rodriguez R, Kinsella TJ. "Halogenated pyrimidines as radiosensitizers for high grade glioma: revisited." International Journal of Radiation Oncology*Biology*Physics, vol. 21, no. 3, 1991, pp. 859-62; discussion 865.

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Kinsella TJ, Gould MN, Mulcahy RT, Ritter MA, Fowler JF. "Keynote address: integration of cytostatic agents and radiation therapy: a different approach to "proliferating" human tumors." International Journal of Radiation Oncology*Biology*Physics, vol. 20, no. 2, 1991, pp. 295-302.

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Kinsella TJ, Miser JS, Waller B, Venzon D, Glatstein E, Weaver-McClure L, Horowitz ME. "Long-term follow-up of Ewing's sarcoma of bone treated with combined modality therapy." International Journal of Radiation Oncology*Biology*Physics, vol. 20, no. 3, 1991, pp. 389-95.

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Hartman KR, Triche TJ, Kinsella TJ, Miser JS. "Prognostic value of histopathology in Ewing's sarcoma. Long-term follow-up of distal extremity primary tumors." Cancer, vol. 67, no. 1, 1991, pp. 163-71.

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Kinsella TJ, DeLuca AM, Barnes M, Anderson W, Terrill R, Sindelar WF. "Threshold dose for peripheral neuropathy following intraoperative radiotherapy (IORT) in a large animal model." International Journal of Radiation Oncology*Biology*Physics, vol. 20, no. 4, 1991, pp. 697-701.

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Mehta MP, Kubsad SS, Fowler JF, Verma AK, Hsieh JT, Kinsella TJ. "90Y.B72.3 against pancreatic cancer: dosimetric and biological analysis." International Journal of Radiation Oncology*Biology*Physics, vol. 19, no. 3, 1990, pp. 627-31.

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Fornace AJ Jr, Dobson PP, Kinsella TJ. "Enhancement of radiation damage in cellular DNA following unifilar substitution with iododeoxyuridine." International Journal of Radiation Oncology*Biology*Physics, vol. 18, no. 4, 1990, pp. 873-8.

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Shanahan TG, Mehta MP, Bertelrud KL, Buchler DA, Frank LE, Gehring MA, Kubsad SS, Utrie PC, Kinsella TJ. "Minimization of small bowel volume within treatment fields utilizing customized "belly boards"." International Journal of Radiation Oncology*Biology*Physics, vol. 19, no. 2, 1990, pp. 469-76.

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Kunugi KA, Vazquez-Padua MA, Miller EM, Kinsella TJ. "Modulation of IdUrd-DNA incorporation and radiosensitization in human bladder carcinoma cells." Cancer Research, vol. 50, no. 16, 1990, pp. 4962-7.

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Kubsad SS, Mackie TR, Gehring MA, Misisco DJ, Paliwal BR, Mehta MP, Kinsella TJ. "Monte Carlo and convolution dosimetry for stereotactic radiosurgery." International Journal of Radiation Oncology*Biology*Physics, vol. 19, no. 4, 1990, pp. 1027-35.

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Oldfield EH, Friedman R, Kinsella T, Moquin R, Olson JJ, Orr K, DeLuca AM. "Reduction in radiation-induced brain injury by use of pentobarbital or lidocaine protection." Journal of Neurosurgery, vol. 72, no. 5, 1990, pp. 737-44.

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Kinsella TJ. "Treatment approaches in soft tissue sarcomas--putting our best foot forward." International Journal of Radiation Oncology*Biology*Physics, vol. 19, no. 2, 1990, pp. 499-501; discussion 505-6.

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Barnes M, Duray P, DeLuca A, Anderson W, Sindelar W, Kinsella T. "Tumor induction following intraoperative radiotherapy: late results of the National Cancer Institute canine trials." International Journal of Radiation Oncology*Biology*Physics, vol. 19, no. 3, 1990, pp. 651-60.

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Chang AE, Collins JM, Speth PA, Smith R, Rowland JB, Walton L, Begley MG, Glatstein E, Kinsella TJ. "A phase I study of intraarterial iododeoxyuridine in patients with colorectal liver metastases." Journal of Clinical Oncology, vol. 7, no. 5, 1989, pp. 662-8.

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Cromack DT, Maher MM, Hoekstra H, Kinsella TJ, Sindelar WF. "Are complications in intraoperative radiation therapy more frequent than in conventional treatment?." Archives of surgery (Chicago, Ill. : 1960), vol. 124, no. 2, 1989, pp. 229-34.

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Kinsella TJ. "Effects of radiation therapy and chemotherapy on testicular function." Progress in clinical and biological research, vol. 302, 1989, pp. 157-71; discussion 172-7.

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Mehta MP, Shahabi S, Jarjour NN, Kinsella TJ. "Endobronchial irradiation for malignant airway obstruction." International Journal of Radiation Oncology*Biology*Physics, vol. 17, no. 4, 1989, pp. 847-51.

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Lack EE, Steinberg SM, White DE, Kinsella T, Glatstein E, Chang AE, Rosenberg SA. "Extremity soft tissue sarcomas: analysis of prognostic variables in 300 cases and evaluation of tumor necrosis as a factor in stratifying higher-grade sarcomas." Journal of surgical oncology, vol. 41, no. 4, 1989, pp. 263-73.

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Bader JL, Horowitz ME, Dewan R, Watkins E, Triche TJ, Tsokos M, Kinsella TJ, Miser JS, Steinberg SM, Glatstein E. "Intensive combined modality therapy of small round cell and undifferentiated sarcomas in children and young adults: local control and patterns of failure." Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, vol. 16, no. 3, 1989, pp. 189-201.

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Sindelar WF, Kinsella TJ. "Intraoperative radiation therapy for locally advanced cancers." Southern Medical Journal, vol. 82, no. 3, 1989, pp. 358-63.

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Hoekstra HJ, Sindelar WF, Kinsella TJ, Mehta DM. "Intraoperative radiation therapy-induced sarcomas in dogs." Radiation Research, vol. 120, no. 3, 1989, pp. 508-15.

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Speth PA, Kinsella TJ, Chang AE, Klecker RW Jr, Belanger K, Smith R, Rowland J, Cupp JE, Collins JM. "Iododeoxyuridine (IdUrd) incorporation into DNA of human hematopoietic cells, normal liver and hepatic metastases in man: as a radiosensitizer and as a marker for cell kinetic studies." International Journal of Radiation Oncology*Biology*Physics, vol. 16, no. 5, 1989, pp. 1247-50.

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Kinsella TJ, Trivette G, Rowland J, Sorace R, Miller R, Fraass B, Steinberg SM, Glatstein E, Sherins RJ. "Long-term follow-up of testicular function following radiation therapy for early-stage Hodgkin's disease." Journal of Clinical Oncology, vol. 7, no. 6, 1989, pp. 718-24.

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Kinsella TJ, Sindelar WF. "Normal tissue tolerance to intraoperative radiation therapy. Experimental and clinical studies." Frontiers of radiation therapy and oncology, vol. 23, 1989, pp. 202-14.

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Mehta MP, Goetowski PG, Kinsella TJ. "Radiation induced thyroid neoplasms 1920 to 1987: a vanishing problem?." International Journal of Radiation Oncology*Biology*Physics, vol. 16, no. 6, 1989, pp. 1471-5.

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Young MM, Kinsella TJ, Miser JS, Triche TJ, Glaubiger DL, Steinberg SM, Glatstein E. "Treatment of sarcomas of the chest wall using intensive combined modality therapy." International Journal of Radiation Oncology*Biology*Physics, vol. 16, no. 1, 1989, pp. 49-57.

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Chang AE, Kinsella T, Glatstein E, Baker AR, Sindelar WF, Lotze MT, Danforth DN Jr, Sugarbaker PH, Lack EE, Steinberg SM. "Adjuvant chemotherapy for patients with high-grade soft-tissue sarcomas of the extremity." Journal of Clinical Oncology, vol. 6, no. 9, 1988, pp. 1491-500.

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Kinsella TJ. "Adjuvant radiation therapy in pancreatic carcinoma: a reappraisal." Cancer investigation, vol. 6, no. 6, 1988, pp. 745-6.

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Brown JM, Hall EJ, Hirst DG, Kinsella TJ, Kligerman MM, Mitchell JB, Travis EJ, Valeriote F. "Chemical modification of radiation and chemotherapy." American Journal of Clinical Oncology, vol. 11, no. 3, 1988, pp. 288-303.

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Speth PA, Kinsella TJ, Belanger K, Klecker RW Jr, Smith R, Rowland JB, Collins JM. "Fluorodeoxyuridine modulation of the incorporation of iododeoxyuridine into DNA of granulocytes: a phase I and clinical pharmacological study." Cancer Research, vol. 48, no. 10, 1988, pp. 2933-7.

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Hoekstra HJ, Restrepo C, Kinsella TJ, Sindelar WF. "Histopathological effects of intraoperative radiotherapy on pancreas and adjacent tissues: a postmortem analysis." Journal of surgical oncology, vol. 37, no. 2, 1988, pp. 104-8.

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Kinsella TJ, Collins J, Rowland J, Klecker R Jr, Wright D, Katz D, Steinberg SM, Glastein E. "Pharmacology and phase I/II study of continuous intravenous infusions of iododeoxyuridine and hyperfractionated radiotherapy in patients with glioblastoma multiforme." Journal of Clinical Oncology, vol. 6, no. 5, 1988, pp. 871-9.

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Kinsella TJ, Sindelar WF, Lack E, Glatstein E, Rosenberg SA. "Preliminary results of a randomized study of adjuvant radiation therapy in resectable adult retroperitoneal soft tissue sarcomas." Journal of Clinical Oncology, vol. 6, no. 1, 1988, pp. 18-25.

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Miser JS, Kinsella TJ, Triche TJ, Tsokos M, Forquer R, Wesley R, Horvath K, Belasco J, Longo DL, Steis R. "Preliminary results of treatment of Ewing's sarcoma of bone in children and young adults: six months of intensive combined modality therapy without maintenance." Journal of Clinical Oncology, vol. 6, no. 3, 1988, pp. 484-90.

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Sindelar WF, Hoekstra HJ, Kinsella TJ, Barnes M, DeLuca AM, Tochner Z, Pass HI, Kranda KC, Terrill RE. "Response of canine esophagus to intraoperative electron beam radiotherapy." International Journal of Radiation Oncology*Biology*Physics, vol. 15, no. 3, 1988, pp. 663-9.

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Speth PA, Kinsella TJ, Chang AE, Klecker RW, Belanger K, Collins JM. "Selective incorporation of iododeoxyuridine into DNA of hepatic metastases versus normal human liver." Clinical pharmacology and therapeutics, vol. 44, no. 4, 1988, pp. 369-75.

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Stea B, Cavazzana A, Kinsella TJ. "Small-cell osteosarcoma: correlation of in vitro and clinical radiation response." International Journal of Radiation Oncology*Biology*Physics, vol. 15, no. 5, 1988, pp. 1233-8.

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Hoekstra HJ, Sindelar WF, Kinsella TJ. "Surgery with intraoperative radiotherapy for sarcomas of the pelvic girdle: a pilot experience." International Journal of Radiation Oncology*Biology*Physics, vol. 15, no. 4, 1988, pp. 1013-6.

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Sindelar WF, Hoekstra HJ, Kinsella TJ. "Surgical approaches and techniques in intraoperative radiotherapy for intra-abdominal, retroperitoneal, and pelvic neoplasms." Surgery, vol. 103, no. 2, 1988, pp. 247-56.

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Kinsella TJ, Sindelar WF, DeLuca AM, Barnes M, Tochner Z, Mixon A, Glatstein E. "Tolerance of the canine bladder to intraoperative radiation therapy: an experimental study." International Journal of Radiation Oncology*Biology*Physics, vol. 14, no. 5, 1988, pp. 939-46.

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Kinsella TJ, Miser JS, Triche TJ, Horvath K, Glatstein E. "Treatment of high-risk sarcomas in children and young adults: analysis of local control using intensive combined modality therapy." NCI monographs : a publication of the National Cancer Institute, no. 6, 1988, pp. 291-6.

PubMed

Kinsella TJ, Dobson PP, Fornace AJ Jr, Barrett SF, Ganges MB, Robbins JH. "Alzheimer's disease fibroblasts have normal repair of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage determined by the alkaline elution technique." Biochemical and Biophysical Research Communications, vol. 149, no. 2, 1987, pp. 355-61.

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Kinsella TJ, Glatstein E. "Clinical experience with intravenous radiosensitizers in unresectable sarcomas." Cancer, vol. 59, no. 5, 1987, pp. 908-15.

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McKenna WG, Barnes MM, Kinsella TJ, Rosenberg SA, Lack EE, Glatstein E. "Combined modality treatment of adult soft tissue sarcomas of the head and neck." International Journal of Radiation Oncology*Biology*Physics, vol. 13, no. 8, 1987, pp. 1127-33.

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Pass HI, Sindelar WF, Kinsella TJ, DeLuca AM, Barnes M, Kurtzman S, Hoekstra H, Tochner Z, Roth J, Glatstein E. "Delivery of intraoperative radiation therapy after pneumonectomy: experimental observations and early clinical results." The Annals of Thoracic Surgery, vol. 44, no. 1, 1987, pp. 14-20.

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Kinsella TJ, Dobson PP, Mitchell JB, Fornace AJ Jr. "Enhancement of X ray induced DNA damage by pre-treatment with halogenated pyrimidine analogs." International Journal of Radiation Oncology*Biology*Physics, vol. 13, no. 5, 1987, pp. 733-9.

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Miller RW, DeGraff W, Kinsella TJ, Mitchell JB. "Evaluation of incorporated iododeoxyuridine cellular radiosensitization by photon activation therapy." International Journal of Radiation Oncology*Biology*Physics, vol. 13, no. 8, 1987, pp. 1193-7.

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Jackson D, Kinsella T, Rowland J, Wright D, Katz D, Main D, Collins J, Kornblith P, Glatstein E. "Halogenated pyrimidines as radiosensitizers in the treatment of glioblastoma multiforme." American Journal of Clinical Oncology, vol. 10, no. 5, 1987, pp. 437-43.

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Hoekstra HJ, Sindelar WF, Kinsella TJ, Oldhoff J. "History, preliminary results, complications, and future prospects of intraoperative radiotherapy." Journal of surgical oncology, vol. 36, no. 3, 1987, pp. 175-82.

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Miser JS, Kinsella TJ, Triche TJ, Tsokos M, Jarosinski P, Forquer R, Wesley R, Magrath I. "Ifosfamide with mesna uroprotection and etoposide: an effective regimen in the treatment of recurrent sarcomas and other tumors of children and young adults." Journal of Clinical Oncology, vol. 5, no. 8, 1987, pp. 1191-8.

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Miller RW, DeGraff W, Mitchell JB, Kinsella TJ. "Photon activation therapy (PAT)." International Journal of Radiation Oncology*Biology*Physics, vol. 13, no. 9, 1987, pp. 1429.

PubMed

Barnes M, Pass H, DeLuca A, Tochner Z, Potter D, Terrill R, Sindelar WF, Kinsella TJ. "Response of the mediastinal and thoracic viscera of the dog to intraoperative radiation therapy (IORT)." International Journal of Radiation Oncology*Biology*Physics, vol. 13, no. 3, 1987, pp. 371-8.

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Stea B, Kinsella TJ, Triche TJ, Horvath K, Glatstein E, Miser JS. "Treatment of pelvic sarcomas in adolescents and young adults with intensive combined modality therapy." International Journal of Radiation Oncology*Biology*Physics, vol. 13, no. 12, 1987, pp. 1797-805.

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Miser JS, Kinsella TJ, Triche TJ, Steis R, Tsokos M, Wesley R, Horvath K, Belasco J, Longo DL, Glatstein E. "Treatment of peripheral neuroepithelioma in children and young adults." Journal of Clinical Oncology, vol. 5, no. 11, 1987, pp. 1752-8.

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Fornace AJ Jr, Dobson PP, Kinsella TJ. "Analysis of the effect of DNA alkylation on alkaline elution." Carcinogenesis, vol. 7, no. 6, 1986, pp. 927-32.

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Potter DA, Kinsella T, Glatstein E, Wesley R, White DE, Seipp CA, Chang AE, Lack EE, Costa J, Rosenberg SA. "High-grade soft tissue sarcomas of the extremities." Cancer, vol. 58, no. 1, 1986, pp. 190-205.

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Belanger K, Klecker RW Jr, Rowland J, Kinsella TJ, Collins JM. "Incorporation of iododeoxyuridine into DNA of granulocytes in patients." Cancer Research, vol. 46, no. 12 Pt 1, 1986, pp. 6509-12.

PubMed

Kinsella TJ, Dobson PP, Mitchell JB. "Interaction of iododeoxyuridine and its primary metabolite, iodouracil on radiation response." International Journal of Radiation Oncology*Biology*Physics, vol. 12, no. 8, 1986, pp. 1519-22.

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Kinsella TJ. "Limited surgery and radiation therapy for sarcomas of the hand and foot." International Journal of Radiation Oncology*Biology*Physics, vol. 12, no. 11, 1986, pp. 2045-6.

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Kinsella TJ, Dobson PP, Russo A, Mitchell JB, Fornace AJ Jr. "Modulation of X ray DNA damage by SR-2508 +/- buthionine sulfoximine." International Journal of Radiation Oncology*Biology*Physics, vol. 12, no. 7, 1986, pp. 1127-30.

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Sindelar WF, Hoekstra H, Restrepo C, Kinsella TJ. "Pathological tissue changes following intraoperative radiotherapy." American Journal of Clinical Oncology, vol. 9, no. 6, 1986, pp. 504-9.

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Russo A, DeGraff W, Kinsella TJ, Gamson J, Glatstein E, Mitchell JB. "Potentiation of chemotherapy cytotoxicity following iododeoxyuridine incorporation in Chinese hamster cells." International Journal of Radiation Oncology*Biology*Physics, vol. 12, no. 8, 1986, pp. 1371-4.

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Tepper JE, Gunderson LL, Goldson AL, Kinsella TJ, Shipley WU, Sindelar WF, Wood WC, Martin JK. "Quality control parameters of intraoperative radiation therapy." International Journal of Radiation Oncology*Biology*Physics, vol. 12, no. 9, 1986, pp. 1687-95.

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Fornace AJ Jr, Dobson PP, Kinsella TJ. "Repair of gamma-ray-induced DNA base damage in xeroderma pigmentosum cells." Radiation Research, vol. 106, no. 1, 1986, pp. 73-7.

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Fornace AJ Jr, Kinsella TJ, Dobson PP, Mitchell JB. "Repair of ionizing radiation DNA base damage in ataxia-telangiectasia cells." Cancer Research, vol. 46, no. 4 Pt 1, 1986, pp. 1703-6.

PubMed

Mitchell JB, Russo A, Kinsella TJ, Glatstein E. "The use of non-hypoxic cell sensitizers in radiobiology and radiotherapy." International Journal of Radiation Oncology*Biology*Physics, vol. 12, no. 8, 1986, pp. 1513-8.

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Kinsella TJ, Russo A, Mitchell JB, Collins JM, Rowland J, Wright D, Glatstein E. "A phase I study of intravenous iododeoxyuridine as a clinical radiosensitizer." International Journal of Radiation Oncology*Biology*Physics, vol. 11, no. 11, 1985, pp. 1941-6.

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Glenn J, Kinsella T, Glatstein E, Tepper J, Baker A, Sugarbaker P, Sindelar W, Roth J, Brennan M, Costa J. "A randomized, prospective trial of adjuvant chemotherapy in adults with soft tissue sarcomas of the head and neck, breast, and trunk." Cancer, vol. 55, no. 6, 1985, pp. 1206-14.

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Klecker RW Jr, Jenkins JF, Kinsella TJ, Fine RL, Strong JM, Collins JM. "Clinical pharmacology of 5-iodo-2'-deoxyuridine and 5-iodouracil and endogenous pyrimidine modulation." Clinical pharmacology and therapeutics, vol. 38, no. 1, 1985, pp. 45-51.

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Russo A, Mitchell J, Kinsella T, Morstyn G, Glatstein E. "Determinants of radiosensitivity." Seminars in oncology, vol. 12, no. 3, 1985, pp. 332-49.

PubMed

Shapiro E, Kinsella TJ, Makuch RW, Fraass BA, Glatstein E, Rosenberg SA, Sherins RJ. "Effects of fractionated irradiation of endocrine aspects of testicular function." Journal of Clinical Oncology, vol. 3, no. 9, 1985, pp. 1232-9.

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Tochner ZA, Kinsella TJ, Glatstein E. "Hepatic irradiation in the management of metastatic hormone-secreting tumors." Cancer, vol. 56, no. 1, 1985, pp. 20-4.

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Morstyn G, Kinsella T, Shan CS, Whang-Peng J, Russo A, Mitchell JB. "In vivo incorporation of bromodeoxyuridine into proliferating cells in the marrow and its effects on granulocyte-macrophage progenitor cells." Experimental hematology, vol. 13, no. 4, 1985, pp. 289-94.

PubMed

Fraass BA, Miller RW, Kinsella TJ, Sindelar WF, Harrington FS, Yeakel K, van de Geijn J, Glatstein E. "Intraoperative radiation therapy at the National Cancer Institute: technical innovations and dosimetry." International Journal of Radiation Oncology*Biology*Physics, vol. 11, no. 7, 1985, pp. 1299-311.

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Kinsella TJ, Glatstein E, Sindelar WF. "Intraoperative radiotherapy." Hospital practice (Office ed.), vol. 20, no. 10, 1985, pp. 125-7, 130-1, 137-41.

PubMed

Mitchell JB, Karawya E, Kinsella TJ, Wilson SH. "Measurement of DNA polymerase beta in skin fibroblast cell lines from patients with ataxia telangiectasia." Mutation research, vol. 146, no. 3, 1985, pp. 295-300.

PubMed

Potter DA, Glenn J, Kinsella T, Glatstein E, Lack EE, Restrepo C, White DE, Seipp CA, Wesley R, Rosenberg SA. "Patterns of recurrence in patients with high-grade soft-tissue sarcomas." Journal of Clinical Oncology, vol. 3, no. 3, 1985, pp. 353-66.

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Fraass BA, Kinsella TJ, Harrington FS, Glatstein E. "Peripheral dose to the testes: the design and clinical use of a practical and effective gonadal shield." International Journal of Radiation Oncology*Biology*Physics, vol. 11, no. 3, 1985, pp. 609-15.

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Glenn J, Sindelar WF, Kinsella T, Glatstein E, Tepper J, Costa J, Baker A, Sugarbaker P, Brennan MF, Seipp C. "Results of multimodality therapy of resectable soft-tissue sarcomas of the retroperitoneum." Surgery, vol. 97, no. 3, 1985, pp. 316-25.

PubMed

Kinsella TJ, Sindelar WF, DeLuca AM, Pezeshkpour G, Smith R, Maher M, Terrill R, Miller R, Mixon A, Harwell JF. "Tolerance of peripheral nerve to intraoperative radiotherapy (IORT): clinical and experimental studies." International Journal of Radiation Oncology*Biology*Physics, vol. 11, no. 9, 1985, pp. 1579-85.

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Kinsella TJ, Russo A, Mitchell JB, Rowland J, Jenkins J, Schwade J, Myers CE, Collins JM, Speyer J, Kornblith P. "A Phase I study of intermittent intravenous bromodeoxyuridine (BUdR) with conventional fractionated irradiation." International Journal of Radiation Oncology*Biology*Physics, vol. 10, no. 1, 1984, pp. 69-76.

PubMed

Schwade JG, Kinsella TJ, Kelly B, Rowland J, Johnston M, Glatstein E. "Clinical experience with intravenous misonidazole for carcinoma of the esophagus: results in attempting radiosensitization of each fraction of exposure." Cancer investigation, vol. 2, no. 2, 1984, pp. 91-5.

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Kinsella TJ, Mitchell JB, Russo A, Aiken M, Morstyn G, Hsu SM, Rowland J, Glatstein E. "Continuous intravenous infusions of bromodeoxyuridine as a clinical radiosensitizer." Journal of Clinical Oncology, vol. 2, no. 10, 1984, pp. 1144-50.

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Mitchell JB, Morstyn G, Russo A, Kinsella TJ, Fornace A Jr, McPherson S, Glatstein E. "Differing sensitivity to fluorescent light in Chinese hamster cells containing equally incorporated quantities of BUdR versus IUdR." International Journal of Radiation Oncology*Biology*Physics, vol. 10, no. 8, 1984, pp. 1447-51.

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Morstyn G, Kinsella T, Hsu SM, Russo A, Gratzner H, Mitchell J. "Identification of bromodeoxyuridine in malignant and normal cells following therapy: relationship to complications." International Journal of Radiation Oncology*Biology*Physics, vol. 10, no. 8, 1984, pp. 1441-5.

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Kinsella TJ, Mitchell JB, McPherson S, Miser J, Triche T, Glatstein E. "In vitro radiation studies on Ewing's sarcoma cell lines and human bone marrow: application to the clinical use of total body irradiation (TBI)." International Journal of Radiation Oncology*Biology*Physics, vol. 10, no. 7, 1984, pp. 1005-11.

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Kinsella TJ, Lichter AS, Miser J, Gerber L, Glatstein E. "Local treatment of Ewing's sarcoma: radiation therapy versus surgery." Cancer treatment reports, vol. 68, no. 5, 1984, pp. 695-701.

PubMed

Russo A, Gianni L, Kinsella TJ, Klecker RW Jr, Jenkins J, Rowland J, Glatstein E, Mitchell JB, Collins J, Myers C. "Pharmacological evaluation of intravenous delivery of 5-bromodeoxyuridine to patients with brain tumors." Cancer Research, vol. 44, no. 4, 1984, pp. 1702-5.

PubMed

Tester WJ, Kinsella TJ, Waller B, Makuch RW, Kelley PA, Glatstein E, DeVita VT. "Second malignant neoplasms complicating Hodgkin's disease: the National Cancer Institute experience." Journal of Clinical Oncology, vol. 2, no. 7, 1984, pp. 762-9.

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Kinsella TJ, Mitchell JB, Russo A, Morstyn G, Glatstein E. "The use of halogenated thymidine analogs as clinical radiosensitizers: rationale, current status, and future prospects: non-hypoxic cell sensitizers." International Journal of Radiation Oncology*Biology*Physics, vol. 10, no. 8, 1984, pp. 1399-406.

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Morstyn G, Hsu SM, Kinsella T, Gratzner H, Russo A, Mitchell JB. "Bromodeoxyuridine in tumors and chromosomes detected with a monoclonal antibody." Journal of Clinical Investigation, vol. 72, no. 5, 1983, pp. 1844-50.

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Sindelar WF, Kinsella T, Tepper J, Travis EL, Rosenberg SA, Glatstein E. "Experimental and clinical studies with intraoperative radiotherapy." Surgery, gynecology & obstetrics, vol. 157, no. 3, 1983, pp. 205-19.

PubMed

Kinsella TJ, Triche TJ, Dickman PS, Costa J, Tepper JE, Glaubiger D. "Extraskeletal Ewing's sarcoma: results of combined modality treatment." Journal of Clinical Oncology, vol. 1, no. 8, 1983, pp. 489-95.

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Kinsella TJ, Loeffler JS, Fraass BA, Tepper J. "Extremity preservation by combined modality therapy in sarcomas of the hand and foot: an analysis of local control, disease free survival and functional result." International Journal of Radiation Oncology*Biology*Physics, vol. 9, no. 8, 1983, pp. 1115-9.

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Mitchell JB, Russo A, Kinsella TJ, Glatstein E. "Glutathione elevation during thermotolerance induction and thermosensitization by glutathione depletion." Cancer Research, vol. 43, no. 3, 1983, pp. 987-91.

PubMed

Carney DN, Mitchell JB, Kinsella TJ. "In vitro radiation and chemotherapy sensitivity of established cell lines of human small cell lung cancer and its large cell morphological variants." Cancer Research, vol. 43, no. 6, 1983, pp. 2806-11.

PubMed

Kinsella TJ, Glaubiger D, Diesseroth A, Makuch R, Waller B, Pizzo P, Glatstein E. "Intensive combined modality therapy including low-dose TBI in high-risk Ewing's Sarcoma Patients." International Journal of Radiation Oncology*Biology*Physics, vol. 9, no. 12, 1983, pp. 1955-60.

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Mitchell JB, Kinsella TJ, Russo A, McPherson S, Rowland J, Smith BH, Kornblith PL, Glatstein E. "Radiosensitization of hematopoietic precursor cells (CFUc) in glioblastoma patients receiving intermittent intravenous infusions of bromodeoxyuridine (BUdR)." International Journal of Radiation Oncology*Biology*Physics, vol. 9, no. 4, 1983, pp. 457-63.

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Kinsella TJ, Glatstein E. "Staging laparotomy and splenectomy for Hodgkin's disease: current status." Cancer investigation, vol. 1, no. 1, 1983, pp. 87-91.

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Fraass BA, Harrington FS, Kinsella TJ, Sindelar WF. "Television system for verification and documentation of treatment fields during intraoperative radiation therapy." International Journal of Radiation Oncology*Biology*Physics, vol. 9, no. 9, 1983, pp. 1409-11.

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Kinsella TJ, Little JB, Nove J, Weichselbaum RR, Li FP, Meyer RJ, Marchetto DJ, Patterson WB. "Heterogeneous response to X-ray and ultraviolet light irradiations of cultured skin fibroblasts in two families with Gardner's Syndrome." JNCI Journal of the National Cancer Institute, vol. 68, no. 5, 1982, pp. 697-701.

PubMed

Kinsella TJ, Mitchell JB, McPherson S, Russo A, Tietze F. "In vitro X-ray sensitivity in ataxia telangiectasis homozygote and heterozygote skin fibroblasts under oxic and hypoxic conditions." Cancer Research, vol. 42, no. 10, 1982, pp. 3950-6.

PubMed

Kinsella TJ, Fraass BA, Glatstein E. "Late effects of radiation therapy in the treatment of Hodgkin's disease." Cancer treatment reports, vol. 66, no. 4, 1982, pp. 991-1001.

PubMed

Kinsella TJ. "Role of combined-modality therapy in the curative management of advanced-stage "favorable" non-Hodgkin's lymphomas." Cancer treatment reports, vol. 66, no. 3, 1982, pp. 421-5.

PubMed

Pretorius HT, Katikineni M, Kinsella TJ, Barsky SH, Brennan MF, Chu EW, Robbins J. "Thyroid nodules after high-dose external radiotherapy. Fine-needle aspiration cytology in diagnosis and management." JAMA, vol. 247, no. 23, 1982, pp. 3217-20.

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Lokich J, Kinsella T, Perri J, Malcolm A, Clouse M. "Concomitant hepatic radiation and intraarterial fluorinated pyrimidine therapy: correlation of liver scan, liver function tests, and plasma CEA with tumor response." Cancer, vol. 48, no. 12, 1981, pp. 2569-74.

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Kinsella TJ, Bloomer WD. "New therapeutic strategies in radiation therapy." JAMA, vol. 245, no. 16, 1981, pp. 1669-74.

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Kinsella TJ, Malcolm AW, Bothe A Jr, Valerio D, Blackburn GL. "Prospective study of nutritional support during pelvic irradiation." International Journal of Radiation Oncology*Biology*Physics, vol. 7, no. 4, 1981, pp. 543-8.

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Kinsella TJ, Bloomer WD, Lavin PT, Knapp RC. "Stage II endometrial carcinoma: 10-year follow-up of combined radiation and surgical treatment." Gynecologic Oncology, vol. 10, no. 3, 1980, pp. 290-7.

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Kinsella TJ, Bloomer WD. "Tolerance of the intestine to radiation therapy." Surgery, gynecology & obstetrics, vol. 151, no. 2, 1980, pp. 273-84.

PubMed

Kinsella TJ, Ahmann DL, Giuliani ER, Lie JT. "Adriamycin cardiotoxicity in stage IV breast cancer: possible enhancement with prior left chest radiation therapy." International Journal of Radiation Oncology*Biology*Physics, vol. 5, no. 11-12, 1979, pp. 1997-2002.

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Research

Funded Research

Past Research Funding (since departure from the National Cancer Institute in October 1987)

A. NIH, 5P30-CA14520:University of Wisconsin Clinical Cancer Center Support; P.P. Carbone, PI; T.J. Kinsella, Senior Leader, 15% effort, 15% salary and Program Leader, 10% effort, 10% salary; 01/01/88-11/01/97; $1,585,076 annual direct cost.

B. NIH 5-U10-CA21076: Eastern Cooperative Oncology Group - D.C. Tormey, PI, Chairman; T.J. Kinsella, Chair, Radiation Therapy Committee, 5% effort, 5% salary; 05/01/89-04/30/94; $343,179 annual direct cost.

C. NIH 5-PO1-CA52686: Growth Factor Alteration of Radiation Response in Tumors, T.J. Kinsella, PI; 40% effort, 25% salary; 09/01/90-08/31/94; $556,000 annual direct cost.

D. NIH R01-CA50595; years 1-3: Radiation and Chemosensitization with Iododeoxyuridine. T.J. Kinsella, PI; 10% effort, 10% salary; 04/01/91-03/31/94; $165,000 annual direct cost.

E. NCI ROP NCI-CM-07301: Phase I and Clinical Pharmacokinetic Studies of Anticancer Agents, P.P. Carbone, M.D., Principal Investigator, T.J. Kinsella, Co-Investigator, 5% effort, 5% salary; 12/01/89-05/31/95; $315,707 annual direct cost.

F. NIH R01-CA52692: Electron Beam Dose Planning Using Monte Carlo Simulation, T.R. Mackie, PI; T.J. Kinsella, Co-investigator, 5% effort, 5% salary; 07/01/90-06/30/93; $352,720 annual direct cost.

G. NIH U01 CA62491: Phase I clinical trials of novel anti-cancer therapies. J. Stewart, P.I.; TJ Kinsella, co-investigator; 5% effort; 5% salary, 04/15/9404/13/98; $181,000 annual direct cost.

H. NIH UO1 CA62421: Therapeutic studies of primary CNS malignancies in adults. M. Prados (U.C.S.F.), P.I. of consortium; T.J. Kinsella and M.P. Mehta, Project directors at U.W.; 5% effort; 0% salary 04/01/9403/31/98; $43,243 annual direct cost.

I. NIH RO1-CA50595; years 4-8: Tumor cell kinetics and S-phase sensitization. T.J. Kinsella, P.I.; 20% effort, 20% salary, 04/01/94 - 3/31/98; $130,000 annual direct cost.

J. Sparta Pharmaceuticals, Inc: In vivo testing of halogenated pyrimidinone compounds. T.J. Kinsella, P.I. 07/01/93- 01/31/00; $60,000 annual direct costs.

K. NIH SBIR - Grant R 44 CA76835: Development of IPdR as a Radiation Sensitizing Drug. H Sands, PI; TJ Kinsella, PI; Case Western Reserve University contract 10% effort; 10% salary; 1/01/00-01/31/02; $302,000 annual direct costs; $87,252 annual direct costs of Case Western Reserve University contract.

L. NIH R01 CA50595: years 8-12: Radiosensitization by the Halogenated Thymidine Analogs. T.J. Kinsella, PI; 20% effort; 20% salary 4/01/98-3/31/02; $129,000 annual direct costs.

M. NIH R01 CA79782: Role of DNA Mismatch Repair in FdUrd-mediated cytotoxicity. DA Boothman, PI; TJ Kinsella Co-investigator, 10% effort, 10% salary; 04/01/99 03/31/03, $162,000 annual direct costs.

N. NIH R01 CA84578: Mismatch repair defects and human tumor radiosensitization. T.J. Kinsella, P.I.; 15% effort; 15% salary 01/01/00 12/31/04, $151,000 annual direct costs.

O. NIH P01 CA 48735: Phthalocyanine Photodynamic Therapy: Mechanistic Studies. N Oleinick, PI; TJ Kinsella, Director-Project 4; Clinical Phase I (± II) Testing with the Silicon Phthalocyanine Pc 4 of PDT. 10% effort: 07/01/00 06/30/05: $655,000 annual direct costs for program project grant, $107,000 annual direct costs for Project 4.

P. NCI RAID Grant #197: IPdR, an oral prodrug for tumor radiosensitization. T.J. Kinsella, PI (11/02 2/06). NCI invested $1,200,000 for drug synthesis, pre-clinical toxicology, GMP testing and completion of investigator-initiated IND to the FDA. (IND awarded)

Q. NASA (Grant# NNC06GA23G): In silico modeling and laboratory study of the role of DNA mismatch repair in processing ionizing radiation damage: estimating risks for space radiation-induced microsatellite instability carcinogenesis. T.J. Kinsella, PI; 10% effort; 09/01/06 08/31/08; $150,000 total costs.

R. NIH CON 103244: Correlative Studies for Clinical Protocol P7336: Phase I/II trial of intravenous triapine in combination with pelvic radiation. T.J. Kinsella, PI; 5% effort; 09/01/06 09/01/08; $38,850 total direct costs.

S. NIH P30 CA43703 - years 8-18: Comprehensive Cancer Center Support Grant. S. Gerson, PI; TJ Kinsella, Co-leader, Radiation and Cellular Stress Program; 10% effort:
11/01/97 - 09/01/08, $2,553,394 annual direct costs in year 18.

T. NIH U56 CA112963: Complex Systems and Control of MMR-deficient cells. T.J. Kinsella, PI; 30% effort: 9/01/04 02/28/10: $312,028 year 5 direct costs (1 year no cost extension through 2/28/11).

U. NIH U56 CA112963: Supplement: Developing a Systems Biology Model of Genetic/Epigenetic Signaling Networks to Predict Tumor Response to Fluoropyridine Based Radiosensitization in Rectal Cancer. T.J. Kinsella, PI; 5% effort; 10/01/07 02/28/11; $120,000 total direct costs.

V. NIH R21 CA140901: Modeling of DNA mismatch repair to improve cancer therapeutics. E. Guran-Cavusoglu PI; T.J.Kinsella, co-investigator; 10% effort; 07/01/09-06/30/11; $150,000 direct year 1 costs.

Background

Education and Training

Year	Degree	Institution
1974	MS	University of Rochester
1974	MD	University of Rochester
1969	BS	St.John Fisher College

Postdoctoral/Other Training

Research Fellow	Harvard School of Public Health, radiobiology	1979-1980	Boston, MA
Clinical Resident	Harvard Medical School, Joint Center for Radiation Therapy, radiation oncology	1977-1979	Boston, MA
Clinical Fellow	Harvard Medical School, Dana Farber Cancer Institute, medical oncology	1976-1977	Boston, MA
Assistant in Medicine	Peter Bent Brigham Hospital	1976-1977	Boston, MA
Intern; Resident	Mayo Clinic, internal medicine	1974-1976	Rochester, MN

Honors and Awards

1983 U.S. Public Health Service, National Institutes of Health Special Achievement Award

1984 National Institutes of Health Award of Merit

2012 National Cancer Institute Director's Service Award

Certification	American Board of Radiology, Radiation oncology	1980-
Certification	American Board of Internal Medicine, Medical oncology	1979-	#63103
Certification	American Board of Internal Medicine, Internal medicine	1977-	#63103
Medical License	Rhode Island	-	#MD 13152
Medical License	New York	-
Medical License	Massachusetts	-
Medical License	Ohio	-

Researchers@Brown

Researchers@Brown

Timothy Kinsella

Professor Emeritus of Radiation Oncology

Overview

Brown Affiliations

Publications Visualize it

Research

Funded Research

Background

Education and Training

Postdoctoral/Other Training

Honors and Awards

Affiliations Visualize it

Affiliations

Credentials/Licenses

Teaching