Upon completing her undergraduate work in business administration, she worked in the securities, advertising and personnel fields, both in Tokyo and New York. She then decided to change her career path to education and began teaching Japanese language at Cornell University, while pursuing graduate studies in applied linguistics and anthropology. Yuko Jackson received a Master's degree in Japanese Linguistics in 1991, and went on to teach Japanese at MIT before coming to Brown University in 1993.
Yuko Jackson has taught all levels of Japanese. She has redesigned and directed 1st year, 2nd year and 4th year Japanese, and created the Business Japanese course (Spring 2006). She is also involved in the Study Abroad Program, serving as the director of Study Abroad Japan and as a faculty adviser for study abroad. She served as a governing board member for the Kyoto Center for Japanese Studies from 1999 to 2005.