Overview

Our lab studies the functional organization and plasticity of neural circuits mediating the sense of touch and pain. We combine mouse molecular-genetic tools, in vivo large-scale spinal cord electrophysiology and calcium imaging, synaptic physiology, computational approaches, and behavioral analyses to reveal fundamental principles of sensory encoding in neural circuits governing body-brain interactions. We also investigate how experience and internal states flexibly shape sensory feature representations in the spinal cord and brain. Our research has profound implications for real-world problems, including chronic pain, neurodevelopmental disorders and movement disorders.

Brown Affiliations

• Neuroscience

Research Areas