Metabolic disorders such as obesity and diabetes and associated cardiovascular diseases are fast becoming the leading global epidemic of our time. The complexities of these diseases require a multidisciplinary attack that must go beyond simply translating basic science discoveries into clinical practice. I am interested in bringing the public health and biological sciences to bear on the emerging challenges of 1) assessing the impact of genes and their interactions with behavior, nutrition, and the environment on health and diseases; 2) critically and systematically evaluating the significance of genetic and dietary variations within populations and applying that knowledge to improve both individual and population health.
Yang, Bo, Glenn, Andrea J., Liu, Qing, Madsen, Tracy, Allison, Matthew A., Shikany, James M., Manson, JoAnn E., Chan, Kei Hang Katie, Wu, Wen-Chih, Li, Jie, Liu, Simin, Lo, Kenneth. "Added Sugar, Sugar-Sweetened Beverages, and Artificially Sweetened Beverages and Risk of Cardiovascular Disease: Findings from the Women’s Health Initiative and a Network Meta-Analysis of Prospective Studies." Nutrients, vol. 14, no. 20, 2022, pp. 4226. |
Li, Jie, Glenn, Andrea J., Yang, Qingling, Ding, Ding, Zheng, Lingling, Bao, Wei, Beasley, Jeannette, LeBlanc, Erin, Lo, Kenneth, Manson, JoAnn E., Philips, Lawrence, Tinker, Lesley, Liu, Simin. "Dietary Protein Sources, Mediating Biomarkers, and Incidence of Type 2 Diabetes: Findings From the Women's Health Initiative and the UK Biobank." Diabetes Care, vol. 45, no. 8, 2022, pp. 1742-1753. |
Li J, Yang Q, An R, Sesso HD, Zhong VW, Chan KHK, Madsen TE, Papandonatos GD, Zheng T, Wu WC, Song Y, Yu X, Liu S. "Famine and Trajectories of Body Mass Index, Waist Circumference, and Blood Pressure in Two Generations: Results From the CHNS From 1993–2015." Hypertension, vol. 79, no. 3, 2022, pp. 518-531. |
Li, Jie, Zou, Xia, Zhong, Fei, Yang, Qingling, Manson, JoAnn E., Papandonatos, George D., Zheng, Lingling, Wu, Wen-Chih, Chan, Kei Hang Katie, Song, Yan, Kuang, Jian, Liu, Simin. "Prenatal exposure to famine and the development of diabetes later in life: an age-period-cohort analysis of the China health and nutrition survey (CHNS) from 1997 to 2015." European Journal of Nutrition, 2022. |
CHEN, Chaolei, NIE, Zhiqiang, WANG, Jiabin, OU, Yanqiu, CAI, Anping, HUANG, Yuqing, YANG, Qingling, LIU, Simin, LI, Jie, FENG, Yingqing. "Prenatal exposure to the Chinese famine of 1959–62 and risk of cardiovascular diseases in adulthood: findings from the China PEACE million persons project." European Journal of Preventive Cardiology, vol. 29, no. 16, 2022, pp. 2111-2119. |
Jie Li1*, Lingling Zheng1, Kei Hang Katie Chan1, Xia Zou1, Jihui Zhang, Jundong Liu, Qingwei Zhong, Tracy E. Madsen, Wen-Chih Wu, JoAnn E. Manson, Xueqing Yu*, Simin Liu*.
"Sex Hormone-Binding Globulin and Risk of Coronary Heart Disease in Men and Women." Clin Chem, 2022.
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Glenn, Andrea J., Li, Jie, Lo, Kenneth, Jenkins, David J.A., Boucher, Beatrice A., Hanley, Anthony J., Kendall, Cyril W.C., Shadyab, Aladdin H., Tinker, Lesley F., Chessler, Steven D., Howard, Barbara V., Liu, Simin, Sievenpiper, John L. "The Portfolio Diet and Incident Type 2 Diabetes: Findings From the Women’s Health Initiative Prospective Cohort Study." Diabetes Care, 2022. |
Zou, Xia, Liu, Shaokun, Li, Jie, Chen, Wen, Ye, Jiali, Yang, Yuan, Zhou, Fenfen, Ling, Li. "Factors Associated With Healthcare Workers' Insomnia Symptoms and Fatigue in the Fight Against COVID-19, and the Role of Organizational Support." Frontiers in Psychiatry, vol. 12, 2021. |
Huang, Mengna, Lo, Kenneth, Li, Jie, Allison, Matthew, Wu, Wen-Chih, Liu, Simin. "Pasta meal intake in relation to risks of type 2 diabetes and atherosclerotic cardiovascular disease in postmenopausal women : findings from the Women’s Health Initiative." BMJ Nutrition, Prevention & Health, vol. 4, no. 1, 2021, pp. 195-205. |
Li, Jie, Owusu, Isaac Kofi, Geng, Qingshan, Folson, Aba Ankomaba, Zheng, Zhichao, Adu‐Boakye, Yaw, Dong, Xinran, Wu, Wen‐Chih, Agyekum, Francis, Fei, Hongwen, Ayetey, Harold, Deng, Mulan, Adomako‐Boateng, Fred, Jiang, Zuxun, Abubakari, Braimah Baba, Xian, Zhao, Fokuoh, Forster Nketiah, Appiah, Lambert Tetteh, Liu, Simin, Lin, Chunying. "Cardiometabolic Risk Factors and Preclinical Target Organ Damage Among Adults in Ghana: Findings From a National Study." Journal of the American Heart Association, vol. 9, no. 24, 2020. |
Gong JH, Lo K, Liu Q, Li J, Lai S, Shadyab AH, Arcan C, Snetselaar L, Liu S. "Dietary Manganese, Plasma Markers of Inflammation, and the Development of Type 2 Diabetes in Postmenopausal Women: Findings From the Women's Health Initiative." Diabetes Care, vol. 43, no. 6, 2020, pp. 1344-1351. |
Lai, Shuiqing, Gopalakrishnan, Geetha, Li, Jie, Liu, Xin, Chen, Yuancheng, Wen, Yuqiong, Zhang, Shuting, Huang, Bizhu, Phornphutkul, Chanika, Liu, Simin, Kuang, Jian. "Familial Dysalbuminemic Hyperthyroxinemia (FDH), Albumin Gene Variant (R218S), and Risk of Miscarriages in Offspring." The American Journal of the Medical Sciences, vol. 360, no. 5, 2020, pp. 566-574. |
Yao, Hongwei, Peterson, Abigail L., Li, Jie, Xu, Haiyan, Dennery, Phyllis A. "Heme Oxygenase 1 and 2 Differentially Regulate Glucose Metabolism and Adipose Tissue Mitochondrial Respiration: Implications for Metabolic Dysregulation." International Journal of Molecular Sciences, vol. 21, no. 19, 2020, pp. 7123. |
Li, Jie, An, Ran, Lai, Shuiqing, Li, Linlin, Liu, Simin, Xu, Haiyan. "Dysregulation of PP2A-Akt interaction contributes to Sucrose non-fermenting related kinase (SNRK) deficiency induced insulin resistance in adipose tissue." Molecular Metabolism, vol. 28, 2019, pp. 26-35. |
Li J, Liu S. "Early life malnutrition is a problem that may be fixed by improving later-life lifestyle: never too late to mend." Heart, vol. 106, no. 3, 2019, pp. heartjnl-2019-316041. |
Li J, Feng B, Nie Y, Jiao P, Lin X, Huang M, An R, He Q, Zhou HE, Salomon A, Sigrist KS, Wu Z, Liu S, Xu H. "Sucrose Nonfermenting-Related Kinase Regulates Both Adipose Inflammation and Energy Homeostasis in Mice and Humans." Diabetes, vol. 67, no. 3, 2018, pp. 400-411. |
Huang, M., Li, J., Ha, M.-A., Riccardi, G., Liu, S. "A systematic review on the relations between pasta consumption and cardio-metabolic risk factors." Nutrition, Metabolism and Cardiovascular Diseases, vol. 27, no. 11, 2017, pp. 939-948. |
Yang, Xue, Huang, Yifan, Sun, Changhao, Li, Jie. "Maternal Prenatal Folic Acid Supplementation Programs Offspring Lipid Metabolism by Aberrant DNA Methylation in Hepatic ATGL and Adipose LPL in Rats." Nutrients, vol. 9, no. 9, 2017, pp. 935. |
Li, Jie, Liu, Simin, Li, Songtao, Feng, Rennan, Na, Lixin, Chu, Xia, Wu, Xiaoyan, Niu, Yucun, Sun, Zongxiang, Han, Tianshu, Deng, Haoyuan, Meng, Xing, Xu, Huan, Zhang, Zhe, Qu, Qiannuo, Zhang, Qiao, Li, Ying, Sun, Changhao. "Prenatal exposure to famine and the development of hyperglycemia and type 2 diabetes in adulthood across consecutive generations: a population-based cohort study of families in Suihua, China." The American Journal of Clinical Nutrition, vol. 105, no. 1, 2017, pp. 221-227. |
Name | Title |
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Liu, Simin | Professor of Epidemiology, Professor of Surgery, Professor of Medicine |
Xu, Haiyan | Associate Professor of Epidemiology (Research) |
(1) Professor, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences
(2) Adjunct Professor of Epidemiology, Brown University
Deputy Director. Guangdong Provincial People’s Hospital, 2021- |
Deputy Director. Guangdong Provincial People’s Hospital, 2021- |
Adjunct Professor. Brown University School of Public Health, 2021- |
Professor, Deputy Director. Guangdong Provincial People’s Hospital, 2020- |