Dr. Shapiro grew up in Lincoln, Rhode Island. He attended college and medical school at the University of Vermont before returning home to Rhode Island where he completed his residency in Pediatrics and fellowship in Pediatric Gastroenterology at Hasbro Children's Hospital. Dr. Shapiro is currently a faculty member in the division of Pediatric Gastroenterology, Nutrition and Liver Diseases at Hasbro Children's Hospital and is assistant professor of Pediatrics at the Warren Alpert Medical School of Brown University. His clinical and research interests are focused on pediatric inflammatory bowel disease.
|Shapiro JM, Hagin SE, Shah SA, Bright R, Mallette M, Moniz H, Giacalone J, Jackvony T, Taleban S, Samad Z, Merrick M, Sands BE, LeLeiko NS. "Corticosteroid Use in a Prospective, Community-Based Cohort of Newly Diagnosed Inflammatory Bowel Disease Patients." Digestive Diseases and Sciences, 2016.|
|Hagin S, Lobato D, Sands BE, Korzenik JR, Merrick M, Shah SA, Bancroft B, Bright R, Law M, Moniz H, Shapiro J, LeLeiko NS. "Dietary Behaviors in Newly Diagnosed Youth with Inflammatory Bowel Disease." Children's Health Care, 2016.|
|Shapiro, Jason M., Subedi, Shova, Machan, Jason T., Cerezo, Carolina S., Ross, Albert M., Shalon, Linda B., Silverstein, Jared A., Herzlinger, Michael I., Kasper, Vania, LeLeiko, Neal S. "Durability of Infliximab Is Associated With Disease Extent in Children With Inflammatory Bowel Disease." Journal of Pediatric Gastroenterology and Nutrition, vol. 62, no. 6, 2016, pp. 867-872.|
|Shapiro JM, Chung W, Ogawa K, Barker L, Carlson R, Wands JR, Li J. "Identification of Tumor Antigen AF20 as Glycosylated Transferrin Receptor 1 in Complex with Heat Shock Protein and/or Transporting ATPase." PLoS ONE, vol. 11, no. 11, 2016, pp. e0165227.|
|Shapiro JM, Zoega H, Shah SA, Bright RM, Mallette M, Moniz H, Grabert SA, Bancroft B, Merrick M, Flowers NT, Samad Z, Lidofsky S, LeLeiko NS, Sands BE. "Incidence of Crohn's Disease and Ulcerative Colitis in Rhode Island: Report from the Ocean State Crohn's and Colitis Area Registry." Inflammatory Bowel Diseases, 2016.|
|Shapiro JM, Subedi S, LeLeiko NS. "Inflammatory Bowel Disease." Pediatrics in Review, vol. 37, no. 8, 2016, pp. 337-47.|
|Grand DJ, Harris A, Shapiro J, Wu E, Giacalone J, Sands BE, Bright R, Moniz H, Mallette M, Leleiko N, Wallenstein S, Samad Z, Merrick M, Shah SA. "Risk Factors for Radiation Exposure in Newly Diagnosed IBD Patients." Abdom Imaging, 2016.|
|Uysal S, Kerur B, Shapiro JM, Snelling LK, Quintos JB. "Acute Erosive Esophagitis as a Rare Complication of Severe Pediatric Diabetes Ketoacidosis." Journal of Pediatric Gastroenterology and Nutrition, vol. 62, no. 4, 2015, pp. e38-9.|
|Saha S, Zhao YQ, Shah SA, Esposti SD, Lidofsky S, Shapiro J, Leleiko N, Bright R, Law M, Moniz H, Samad Z, Merrick M, Sands BE. "Body image dissatisfaction in patients with inflammatory bowel disease." Inflammatory Bowel Diseases, vol. 21, no. 2, 2015, pp. 345-52.|
|Shapiro JM, Cho JH, Sands BE, LeLeiko NS. "Bridging the gap between host immune response and intestinal dysbiosis in inflammatory bowel disease: does immunoglobulin A mark the spot?." Clinical Gastroenterology and Hepatology, vol. 13, no. 5, 2015, pp. 842-846.|
|Shapiro, Jason M., Kerur, Basavaraj. "Do Orally Administered Immunoglobulin-Based Agents Represent the Future of IBD Therapeutics?." Digestive Diseases and Sciences, vol. 60, no. 11, 2015, pp. 3155-3157.|
|"Do Orally Administered Immunoglobulin-Based Agents Represent the Future of IBD Therapeutics?." Digestive Diseases and Sciences, 2015.|
Jason M. Shapiro
Neal S. LeLeiko
Beth A. Pinkos.
"Enteral Nutrition." Pediatric Gastrointestinal and Liver Disease, 5th Edition, edited by Robert Wyllie, Jeffrey S. Hyams, United States, Elsevier, 2015, pp. 89-1-89-17e3.
|Townsend P, Zhang Q, Shapiro J, Webb-Robertson BJ, Bramer L, Schepmoes AA, Weitz KK, Mallette M, Moniz H, Bright R, Merrick M, Shah SA, Sands BE, Leleiko N. "Serum Proteome Profiles in Stricturing Crohn's Disease: A Pilot Study." Inflammatory Bowel Diseases, vol. 21, no. 8, 2015, pp. 1935-41.|
|Krishnarao A, de Leon L, Bright R, Moniz H, Law M, Leleiko N, Sands BE, Merrick M, Shapiro J, Wallenstein S, Giacalone J, Shah SA. "Testing for Clostridium difficile in patients newly diagnosed with inflammatory bowel disease in a community setting." Inflammatory Bowel Diseases, vol. 21, no. 3, 2015, pp. 564-9.|
|Reed-Knight B, Lobato D, Hagin S, McQuaid EL, Seifer R, Kopel SJ, Boergers J, Nassau JH, Suorsa K, Bancroft B, Shapiro J, Leleiko NS. "Depressive symptoms in youth with inflammatory bowel disease compared with a community sample." Inflammatory Bowel Diseases, vol. 20, no. 4, 2014, pp. 614-21.|
|LeLeiko NS, Lobato D, Hagin S, Hayes C, McQuaid EL, Seifer R, Kopel SJ, Boergers J, Nassau J, Suorsa K, Shapiro J, Bancroft B. "6-Thioguanine Levels in Pediatric IBD Patients." Inflammatory Bowel Diseases, vol. 19, no. 12, 2013, pp. 2652-2658.|
Jason M. Shapiro
Neal S. LeLeiko.
"New Guidelines for Diagnosis and Treatment of C. difficile." AAP Grand Rounds, vol. 19, no. 4, 2013, pp. 60.
|LeLeiko NS, Lobato D, Hagin S, McQuaid E, Seifer R, Kopel SJ, Boergers J, Nassau J, Suorsa K, Shapiro J, Bancroft B. "Rates and predictors of oral medication adherence in pediatric patients with IBD." Inflammatory Bowel Diseases, vol. 19, no. 4, 2013, pp. 832-9.|
|Shapiro JM, Kawatu D, Bancroft B, LeLeiko N. "Inflammatory bowel disease in pediatrics." Medicine and health, Rhode Island, vol. 92, no. 4, 2009, pp. 135, 145-7.|
My goal is to determine the factors associated with favorable outcomes of childhood inflammatory bowel disease (IBD). IBD is a chronic, debilitating condition characterized by relapsing and remitting episodes of gastrointestinal inflammation. Pathogenesis has been attributed to a combination of causative factors including genetic predisposition, alterations in the gut microbiome, defects in the innate and adaptive immune system and various putative environmental exposures. The incidence of IBD in children has inexplicably increased over the past few decades and despite new therapies, little is known about how to optimize these treatments to achieve the best long-term outcomes. In 2010 I received an NIH T32 Ruth L. Kirschstein National Research Award to complete my last 2 years of pediatric gastroenterology fellowship here at Rhode Island Hospital/Hasbro Children’s Hospital. Under the mentorship of Dr. Jack Wands, my work focused on the identification and characterization of novel biomarkers of colonic dysplasia, a precursor of colon cancer in patients with long standing IBD. My academic focus remains on clinical and translational aspects of inflammatory bowel disease research. I am currently the co-principal investigator of the Ocean State Crohn’s and Colitis Area Registry (OSCCAR) along with the primary principal investigator, Dr. Bruce E. Sands, the Dr. Burrill B. Crohn Professor of Medicine and Chief of the Henry D. Janowitz Division of Gastroenterology at the Icahn School of Medicine at Mount Sinai. A well defined, inception cohort of patients with newly diagnosed IBD in the state of Rhode Island, OSCCAR represents a unique opportunity to study the natural history of IBD over time. In addition, leveraging the clinical, microbial and genomic data obtained from analysis of the various OSCCAR biospecimens represents an exciting opportunity to further define the immunopathogenesis of inflammatory bowel disease.
National Institutes of Health Loan Repayment Program Award
AAP Resident Scholarship
Alpha Omega Alpha
Phi Beta Kappa
Freeman Scholar - University of Vermont College of Medicine
Simon Family Scholar - University of Vermont College of Arts and Sciences
|De La Monte, Suzanne||Professor of Pathology and Laboratory Medicine, Professor of Neurosurgery|
|Leleiko, Neal||Professor of Pediatrics|
|Lobato, Debra||Professor Emerita of Psychiatry and Human Behavior|
|Shah, Samir||Clinical Professor of Medicine|
|Wands, Jack||Professor of Medical Science, Jeffrey and Kimberley Greenberg-Artemis and Martha Joukowsky Professor of Gastroenterology, Professor of Medicine|
Hasbro Children's Hospital, Attending Physician
Women and Infants Hospital, Consulting Physician
North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, Member
Crohn's and Colitis Foundation of America, Member
American Gastroenterological Association, Member