Dr. Ehsan is an Adult Cardiac Surgeon at Rhode Island Hospital and is a Professor of Surgery at the Brown Alpert Medical School. He is also the Director of Minimally Invasive Cardiac Surgery. He provides surgical treatment for all forms of adult cardiovascular disease with a particular interest in valvular surgery and an emphasis on mitral valve repair and percutaneous aortic valve therapies. He is also well versed in the current state of atrial fibrillation surgery as it applies to stand-alone and concomitant procedures. He has an academic background in cardiovascular gene and cell based therapies. Specifically, Dr. Ehsan has examined the use of decoy oligonucleotides in vein grafts as a means of prolonging graft patency. He has also examined the role of nuclear hormone receptors and their role in vein graft pathobiology. Additionally, Dr. Ehsan participates in clinical outcomes research related to the effect of blood transfusions on patients undergoing cardiac surgical procedures. He also has an interest in examining disparities in access to care for patients receiving cardiac surgical therapies. These efforts have resulted in numerous peer reviewed publications.
Waksman R, Corso PJ, Torguson R, Gordon P, Ehsan A, Wilson SR, Goncalves J, Levitt R, Hahn C, Parikh P, Bilfinger T, Butzel D, Buchanan S, Hanna N, Garrett R, Buchbinder M, Asch F, Weissman G, Ben-Dor I, Shults C, Bastian R, Craig PE, Ali S, Garcia-Garcia HM, Kolm P, Zou Q, Satler LF, Rogers T. "Transcatheter Aortic Valve Replacement in Low-Risk Patients: One-Year Results from the LRT Trial." JACC: Cardiovascular Interventions, 2019. |
Kolte D, Beale C, Aronow HD, Kennedy KF, Apostolidou E, Sellke FW, Sharaf BL, Gordon PC, Abbott JD, Ehsan A. "Trends and outcomes of red blood cell transfusion in patients undergoing transcatheter aortic valve replacement in the United States." The Journal of Thoracic and Cardiovascular Surgery, 2019. |
McDermott J, Zeymo A, Chan K, Ehsan A, Crocker A, Xiao D, Ahluwalia JS, DeLeire T, Shara N, Al-Refaie W. "Affordable Care Act's Medicaid Expansion and Use of Regionalized Surgery at High-Volume Hospitals." Journal of the American College of Surgeons, vol. 227, no. 5, 2018, pp. 507-520.e9. |
Apostolidou E, Aronow HD, Beale CE, Kolte D, Kennedy KF, Sellke FW, Gordon PC, Sharaf B, Ehsan A. "Association Between Red Blood Cell Transfusion and Clinical Outcomes Among Patients Undergoing Transcatheter Aortic Valve Replacement." The Annals of Thoracic Surgery, vol. 107, no. 6, 2018, pp. 1791-1798. |
Kolte, Dhaval, Goldsweig, Andrew, Kennedy, Kevin F., Abbott, J. Dawn, Gordon, Paul C., Sellke, Frank W., Ehsan, Afshin, Sodha, Neel, Sharaf, Barry L., Aronow, Herbert D. "Comparison of Incidence, Predictors, and Outcomes of Early Infective Endocarditis after Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in the United States." The American Journal of Cardiology, vol. 122, no. 12, 2018, pp. 2112-2119. |
Sabe SA, Feng J, Liu Y, Scrimgeour LA, Ehsan A, Sellke FW. "Decreased contractile response of peripheral arterioles to serotonin after CPB in patients with diabetes." Surgery, vol. 164, no. 2, 2018, pp. 288-293. |
Liu, Yuhong, Cole, Victoria, Lawandy, Isabella, Ehsan, Afshin, Sellke, Frank W., Feng, Jun. "Decreased coronary arteriolar response to K<sub>Ca</sub> channel opener after cardioplegic arrest in diabetic patients." Molecular and Cellular Biochemistry, vol. 445, no. 1-2, 2018, pp. 187-194. |
Sellke, Nicholas, Kuczmarski, Alex, Lawandy, Isabella, Cole, Victoria L., Ehsan, Afshin, Singh, Arun K., Liu, Yuhong, Sellke, Frank W., Feng, Jun. "Enhanced coronary arteriolar contraction to vasopressin in patients with diabetes after cardiac surgery." The Journal of Thoracic and Cardiovascular Surgery, 2018. |
Naeem SS, Sodha NR, Sellke FW, Ehsan A. "Impact of Packed Red Blood Cell and Platelet Transfusions in Patients Undergoing Dissection Repair." Journal of Surgical Research, vol. 232, 2018, pp. 338-345. |
Waksman, Ron, Rogers, Toby, Torguson, Rebecca, Gordon, Paul, Ehsan, Afshin, Wilson, Sean R., Goncalves, John, Levitt, Robert, Hahn, Chiwon, Parikh, Puja, Bilfinger, Thomas, Butzel, David, Buchanan, Scott, Hanna, Nicholas, Garrett, Robert, Asch, Federico, Weissman, Gaby, Ben-Dor, Itsik, Shults, Christian, Bastian, Roshni, Craig, Paige E., Garcia-Garcia, Hector M., Kolm, Paul, Zou, Quan, Satler, Lowell F., Corso, Paul J. "Transcatheter Aortic Valve Replacement in Low-Risk Patients with Symptomatic Severe Aortic Stenosis." Journal of the American College of Cardiology, 2018. |
Feng J, Anderson K, Liu Y, Singh AK, Ehsan A, Sellke FW. "Cyclooxygenase 2 contributes to bradykinin-induced microvascular responses in peripheral arterioles after cardiopulmonary bypass." Journal of Surgical Research, vol. 218, 2017, pp. 246-252. |
Feng, Jun, Anderson, Kelsey, Singh, Arun K., Ehsan, Afshin, Mitchell, Hunter, Liu, Yuhong, Sellke, Frank W. "Diabetes Upregulation of Cyclooxygenase 2 Contributes to Altered Coronary Reactivity After Cardiac Surgery." The Annals of Thoracic Surgery, vol. 104, no. 2, 2017, pp. 568-576. |
Feng, Jun, Liu, Yuhong, Singh, Arun K., Ehsan, Afshin, Sellke, Nicholas, Liang, Justin, Sellke, Frank W. "Effects of diabetes and cardiopulmonary bypass on expression of adherens junction proteins in human peripheral tissue." Surgery, vol. 161, no. 3, 2017, pp. 823-829. |
Sardar, M. Rizwan, Khan, Zubair A., Abraham, Anu, Saeed, Wajeeha, Farhan, Muhammad, Kolte, Dhaval, Sharaf, Barry, Gordon, Paul, Sellke, Frank, Sodha, Neel R., Aronow, Herbert D., Ehsan, Afshin. "Management strategies and possible risk factors for ventricular septal defects after transcatheter aortic valve replacement: Case series from a single center and review of literature." Cardiovascular Revascularization Medicine, vol. 18, no. 6, 2017, pp. 462-470. |
Goldsweig AM, Kennedy KF, Kolte D, Abbott JD, Gordon PC, Sharaf BL, Sellke FW, Ehsan A, Sodha NR, Rutar F, Aronow HD. "Predictors of patient radiation exposure during transcatheter aortic valve replacement." Catheterization and Cardiovascular Interventions, vol. 92, no. 4, 2017, pp. 768-774. |
Sardar, M Rizwan, Goldsweig, Andrew M, Abbott, J Dawn, Sharaf, Barry L, Gordon, Paul C, Ehsan, Afshin, Aronow, Herbert D. "Vascular complications associated with transcatheter aortic valve replacement." Vascular Medicine, vol. 22, no. 3, 2017, pp. 234-244. |
Feng, Jun, Liu, Yuhong, Singh, Arun K., Ehsan, Afshin, Sellke, Nicholas, Liang, Justin, Sellke, Frank W. "Effects of diabetes and cardiopulmonary bypass on expression of adherens junction proteins in human peripheral tissue." Surgery, 2016. |
Ollila T, Naeem S, Poppas A, McKendall G, Ehsan A. "Embolization of Inferior Vena Cava Filter Tyne and Right Ventricular Perforation: A Cardiac Missile." The Annals of Thoracic Surgery, vol. 102, no. 6, 2016, pp. e515-e516. |
Stone GW, Sabik JF, Serruys PW, Simonton CA, Généreux P, Puskas J, Kandzari DE, Morice MC, Lembo N, Brown WM 3rd, Taggart DP, Banning A, Merkely B, Horkay F, Boonstra PW, van Boven AJ, Ungi I, Bogáts G, Mansour S, Noiseux N, Sabaté M, Pomar J, Hickey M, Gershlick A, Buszman P, Bochenek A, Schampaert E, Pagé P, Dressler O, Kosmidou I, Mehran R, Pocock SJ, Kappetein AP, EXCEL Trial Investigators. "Everolimus-Eluting Stents or Bypass Surgery for Left Main Coronary Artery Disease." New England Journal of Medicine, vol. 375, no. 23, 2016, pp. 2223-2235. |
Ehsan A, Ng T. "The latissimus dorsi flap continues to play an important role in cardiothoracic surgery." The Journal of Thoracic and Cardiovascular Surgery, vol. 152, no. 5, 2016, pp. 1452-1453. |
Miller R, Covington S, Taranto S, Carrico R, Ehsan A, Friedman B, Green M, Ison MG, Kaul D, Kubak B, Lebovitz DJ, Lyon GM, Nalesnik MA, Pruett TL, Teperman L, Vasudev B, Blumberg E. "Communication gaps associated with donor-derived infections." American Journal of Transplantation, vol. 15, no. 1, 2015, pp. 259-64. |
Liu Y, Xie A, Singh AK, Ehsan A, Choudhary G, Dudley S, Sellke FW, Feng J. "Inactivation of Endothelial Small/Intermediate Conductance of Calcium‐Activated Potassium Channels Contributes to Coronary Arteriolar Dysfunction in Diabetic Patients." Journal of the American Heart Association, vol. 4, no. 8, 2015, pp. e002062. |
Fani Srour, John, Mazza, Joseph P., Ehasn, Afshin, Donaldson, David, Levine, Daniel. "Thrombus in transit: a link between pulmonary embolism and neurological embolic events." International Journal of Cardiology, vol. 174, no. 2, 2014, pp. e47-e49. |
Ehsan A, Sellke FW. "Invited commentary." The Annals of Thoracic Surgery, vol. 95, no. 5, 2013, pp. 1530-1. |
Ehsan A, McGraw AP, Aronovitz MJ, Galayda C, Conte MS, Karas RH, Jaffe IZ. "Mineralocorticoid receptor antagonism inhibits vein graft remodeling in mice." The Journal of Thoracic and Cardiovascular Surgery, vol. 145, no. 6, 2013, pp. 1642-9, 1649.e1. |
Shuhaiber JH, Fava JL, Shin T, Dobrilovic N, Ehsan A, Bert A, Sellke F. "The influence of seasons and lunar cycle on hospital outcomes following ascending aortic dissection repair." Interactive cardiovascular and thoracic surgery, vol. 17, no. 5, 2013, pp. 818-22. |
Aaronson KD, Slaughter MS, Miller LW, McGee EC, Cotts WG, Acker MA, Jessup ML, Gregoric ID, Loyalka P, Frazier OH, Jeevanandam V, Anderson AS, Kormos RL, Teuteberg JJ, Levy WC, Naftel DC, Bittman RM, Pagani FD, Hathaway DR, Boyce SW, HeartWare Ventricular Assist Device (HVAD) Bridge to Transplant ADVANCE Trial Investigators. "Use of an intrapericardial, continuous-flow, centrifugal pump in patients awaiting heart transplantation." Circulation, vol. 125, no. 25, 2012, pp. 3191-200. |
Newfell BG, Iyer LK, Mohammad NN, McGraw AP, Ehsan A, Rosano G, Huang PL, Mendelsohn ME, Jaffe IZ. "Aldosterone regulates vascular gene transcription via oxidative stress-dependent and -independent pathways." Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 31, no. 8, 2011, pp. 1871-80. |
Estes NA 3rd, Homoud M, Weinstock J, Foote C, Garlitski A, Link M, Ehsan A. "Interdisciplinary strategies for arrhythmia program development: measuring quality, performance, and outcomes." Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, vol. 31, no. 1, 2011, pp. 91-9. |
Jaffe IZ, Newfell BG, Aronovitz M, Mohammad NN, McGraw AP, Perreault RE, Carmeliet P, Ehsan A, Mendelsohn ME. "Placental growth factor mediates aldosterone-dependent vascular injury in mice." Journal of Clinical Investigation, vol. 120, no. 11, 2010, pp. 3891-900. |
Slaughter MS, Rogers JG, Milano CA, Russell SD, Conte JV, Feldman D, Sun B, Tatooles AJ, Delgado RM 3rd, Long JW, Wozniak TC, Ghumman W, Farrar DJ, Frazier OH, HeartMate II Investigators. "Advanced heart failure treated with continuous-flow left ventricular assist device." New England Journal of Medicine, vol. 361, no. 23, 2009, pp. 2241-51. |
Backlund M, Paukku K, Daviet L, De Boer RA, Valo E, Hautaniemi S, Kalkkinen N, Ehsan A, Kontula KK, Lehtonen JY. "Posttranscriptional regulation of angiotensin II type 1 receptor expression by glyceraldehyde 3-phosphate dehydrogenase." Nucleic acids research, vol. 37, no. 7, 2009, pp. 2346-58. |
Shekar PS, Ehsan A, Gilfeather MS, Lekowski RW Jr, Couper GS. "Arterial pressure monitoring during cardiopulmonary bypass using axillary arterial cannulation." Journal of Cardiothoracic and Vascular Anesthesia, vol. 19, no. 5, 2005, pp. 665-6. |
Aranki SF, Shekar PS, Ehsan A, Byrne-Taft M, Couper GS. "Evaluation of the enclose proximal anastomosis device in coronary artery bypass grafting." The Annals of Thoracic Surgery, vol. 80, no. 3, 2005, pp. 1091-5. |
Ehsan A, Singh H, Vargas SO, Sachweh J, Jonas RA. "Neoaortic aneurysm after stage I Norwood reconstruction." The Annals of Thoracic Surgery, vol. 79, no. 3, 2005, pp. e23-5. |
Ehsan A, Shekar P, Aranki S. "Innovative Surgical Strategies: Minimally Invasive CABG and Off-pump CABG." Current treatment options in cardiovascular medicine, vol. 6, no. 1, 2004, pp. 43-51. |
Sharma S, Ehsan A, Couper GS, Shernan SK, Wholey RM, Aranki SF. "Unrecognized left ventricular thrombus during reoperative coronary artery bypass grafting." The Annals of Thoracic Surgery, vol. 78, no. 5, 2004, pp. e79-80. |
Huber PE, Mann MJ, Melo LG, Ehsan A, Kong D, Zhang L, Rezvani M, Peschke P, Jolesz F, Dzau VJ, Hynynen K. "Focused ultrasound (HIFU) induces localized enhancement of reporter gene expression in rabbit carotid artery." Gene therapy, vol. 10, no. 18, 2003, pp. 1600-7. |
Griese DP, Ehsan A, Melo LG, Kong D, Zhang L, Mann MJ, Pratt RE, Mulligan RC, Dzau VJ. "Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy." Circulation, vol. 108, no. 21, 2003, pp. 2710-5. |
Ehsan A, Mann MJ, Dell'Acqua G, Tamura K, Braun-Dullaeus R, Dzau VJ. "Endothelial healing in vein grafts: proliferative burst unimpaired by genetic therapy of neointimal disease." Circulation, vol. 105, no. 14, 2002, pp. 1686-92. |
Melo LG, Agrawal R, Zhang L, Rezvani M, Mangi AA, Ehsan A, Griese DP, Dell'Acqua G, Mann MJ, Oyama J, Yet SF, Layne MD, Perrella MA, Dzau VJ. "Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene." Circulation, vol. 105, no. 5, 2002, pp. 602-7. |
Dzau VJ, Mann MJ, Ehsan A, Griese DP. "Gene therapy and genomic strategies for cardiovascular surgery: The emerging field of surgiomics." The Journal of Thoracic and Cardiovascular Surgery, vol. 121, no. 2, 2001, pp. 206-16. |
Ehsan A, Mann MJ, Dell'Acqua G, Dzau VJ. "Long-term stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapy." The Journal of Thoracic and Cardiovascular Surgery, vol. 121, no. 4, 2001, pp. 714-22. |
Ehsan A, Mann MJ. "Antisense and gene therapy to prevent restenosis." Vascular Medicine, vol. 5, no. 2, 2000, pp. 103-14. |
Mann, Michael J, Ehsan, Afshin, Dzau, Victor J. "Vascular growth factors as an adjunct to surgical revascularization." ACC Current Journal Review, vol. 9, no. 4, 2000, pp. 43-46. |
Mann MJ, Whittemore AD, Donaldson MC, Belkin M, Conte MS, Polak JF, Orav EJ, Ehsan A, Dell'Acqua G, Dzau VJ. "Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: the PREVENT single-centre, randomised, controlled trial." The Lancet, vol. 354, no. 9189, 1999, pp. 1493-8. |
Ortega AE, Peters JH, Incarbone R, Estrada L, Ehsan A, Kwan Y, Spencer CJ, Moore-Jeffries E, Kuchta K, Nicoloff JT. "A prospective randomized comparison of the metabolic and stress hormonal responses of laparoscopic and open cholecystectomy." Journal of the American College of Surgeons, vol. 183, no. 3, 1996, pp. 249-56. |
Clark GW, Peters JH, Ireland AP, Ehsan A, Hagen JA, Kiyabu MT, Bremner CG, DeMeester TR. "Nodal metastasis and sites of recurrence after en bloc esophagectomy for adenocarcinoma." The Annals of Thoracic Surgery, vol. 58, no. 3, 1994, pp. 646-53; discussion 653-4. |
Costantini M, Crookes PF, Bremner RM, Hoeft SF, Ehsan A, Peters JH, Bremner CG, DeMeester TR. "Value of physiologic assessment of foregut symptoms in a surgical practice." Surgery, vol. 114, no. 4, 1993, pp. 780-6; discussion 786-7. |
Factor XIa Inhibitor in Cardiopulmonary Bypass
Award Type: eXIthera Industry Award
Role: Principal Investigator
Support: $150,000 direct costs
Project Period: August 2018 – August 2019
Feasibility of Transcatheter Aortic Valve Replacement in Low-Risk Patients with Symptomatic, Severe Aortic Stenosis
Role: Site Co-Principal Investigator
Support: Lifespan total direct costs
Project Period: August 2016 – January 2018
A Retrospective Chart Review Study to Investigate Bleeding Risk and Blood Transfusion Requirements in Patients Undergoing Complex Cardiovascular Surgery in the United States
Award Type: CSL Behring Industry Award
Role: Site Principal Investigator
Support: RIH total direct costs
Project Period: October 2014 – April 2015
The EXCEL Clinical Trial
Award Type: Industry Award
Role: Site Co-Principal Investigator
Support: Lifespan total direct costs
Project Period: August 2012 – July 2014
The Role of the Mineralocorticoid Receptor in Vein Graft Intimal Hyperplasia
Award Type: Department of Surgery Start-up Funds, Tufts Medical Center
Role: Principal Investigator
Support: $ 150,000
Project Period: February 2009 - July 2012
The Role of the Mineralocorticoid Receptor in Vein Graft Intimal Hyperplasia
Award Type: Tufts Medical Center Intramural Grant
Role: Principal Investigator
Support: $30,000
Project Period: February 2010 - January 2011
The Cost Effectiveness of Left Ventricular Assist Device Destination Therapy Compared to Cardiac Transplantation
Award Type: Thoratec Corporation Industry Award
Role: Principal Investigator
Support: $12,000
Project Period: May 2010 - April 2011
Genetic Engineering of Vein Grafts
Award Type: American Heart Association Post-doctoral Fellowship Grant
Role: Principal Investigator
Support: $60,000
Project Period: July 1998 - June 2000
Year | Degree | Institution |
---|---|---|
1994 | MD | University of Southern California |
1990 | BS | University of California, Los Angeles |
Resident | Brigham and Women's Hospital, cardiothoracic surgery | 2002-2004 | |
Resident | UCSD, general surgery | 2000-2002 | |
Postdoctoral Fellow | Harvard university , Brigham and Women's Hospital, Cardiovascular Research Center | 1997-2000 | |
Resident | UCSD, general surgery | 1995-1997 | |
Intern | UCSD, general surgery | 1994-1995 |
Master of Arts, ad eundem, Brown University, 2023
Deans Excellence in Teaching Award, Warren Alpert Medical School of Brown University, 2022
Deans Excellence in Teaching Award, Warren Alpert Medical School of Brown University, 2020
Deans Excellence in Teaching Award, Warren Alpert Medical School of Brown University, 2019
Office of Medical Education Letter of Recognition, Warren Alpert Medical School of Brown University, 2018
Nominee, Dr. Dwight C. McGoon Teaching Award, American Association for Thoracic Surgery, 2010
Notable Teaching Citation, Tufts University School of Medicine, 2008
Alley-Sheridan Scholarship to attend the Brandies Leadership Program in Health Policy and Management, 2007
ACCF MRI/CT Travel Award, 2003
UCSD Department of Surgery Chairman's Award for Excellence, 2002
San Diego Metropolitan's 40 under Forty Award, 2001
AVENTIS Surgery Residents Scholarship, 2001
Administrative/Executive Chief Resident, 2001
Runner-up, Best Over-all Paper in, "The Best and Brightest: Current Research in Surgery", San Diego Chapter of the American College of Surgeons, 2001
Runner-up, Best General Surgery Paper in, "The Best and Brightest: Current Research in Surgery", San Diego Chapter of the American College of Surgeons, 2001
Alpha Omega Alpha Medical Honors Society, 1993
Deans Scholar for Academic Excellence, USC School of Medicine, 1993
Deans Scholar for Academic Excellence, USC School of Medicine, 1991
Name | Title |
---|---|
Apostolidou, Eirini | Assistant Professor of Medicine |
Aronow, Herbert | Associate Professor of Medicine |
Clements, Richard | Assistant Professor of Surgery (Research) |
Feng, Jun | Professor of Surgery |
Sellke, Frank | Karl E. Karlson, MD and Gloria A. Karlson Professor of Cardiothoracic Surgery, Professor of Surgery |
Sodha, Neel | Associate Professor of Surgery |
Massachusetts Medical Society, Member, 1997
Cardiothoracic Surgery Network, Member, 1998
Heart Failure Society of America, 2004 - 2010
American College of Surgeons, Associate Fellow, 2004 - 2012
International Society for Heart and Lung Transplantation, 2005 - 2012
Society of Thoracic Surgeons, Member, 2005 - present
Thoracic Surgery Directors Association, 2009 - 2012
Massachusetts Chapter of the American College of Surgeons, 2010 - 2012
Heart Valve Society of America, Member, 2010 - 2014
European Association for Cardio-Thoracic Surgery, Member, 2011 - present
Society of Heart Valve Disease, Member, 2011 - 2014
National Association for Healthcare Quality, Member, 2011 - present
Association for Academic Surgeons, Member, 2011 - present
American College of Surgeons, Fellow, 2012 - present
American Heart Association, Member, 2013 - 2018
Heart Valve Society, Member, 2016 - present
International Society of Minimally Invasive Cardiac Surgery, Member, 2015 - present
American College of Cardiology, Fellow, 2016 - present
Eastern Cardiothoracic Surgical Society, Member, 2017 - present
American Heart Association, Fellow, 2018 - present
American Association for Thoracic Surgery, Member, 2019 - present
Society of University Surgeons, Member, 2019 - present
New England Surgical Society, Member, 2022 - present
Medical License | Rhode Island | 2012- | |
American Board of Thoracic Surgery | 2005- | ||
American Board of Surgery | 2003- | ||
Medical License | Massachusetts | 1997- | |
Medical License | California | 1995- |
Co-Director, CVI Quality Steering Committee. Rhode Island Hospital, 2018- |
Director of Minimally Invasive Cardiac Surgery. Rhode Island Hospital, 2015- |