Chanelle J. Howe Assistant Professor of Epidemiology

Dr. Howe is an Assistant Professor in the Department of Epidemiology within the Brown University School of Public Health. She has an appointment with the Center for Population Health and Clinical Epidemiology and is a member of the Lifespan/Tufts/Brown Center for AIDS Research. Prior to joining the faculty at Brown, Dr. Howe obtained an MPH in Epidemiology from the Columbia University Mailman School of Public Health in 2004. She received her PhD in Epidemiology as well as an MHS in Biostatistics from the Johns Hopkins Bloomberg School of Public Health in 2009. From 2009 to 2011, Dr. Howe completed postdoctoral training in the Department of Epidemiology at the University of North Carolina Gillings School of Global Public Health.

Brown Affiliations

Research Areas

scholarly work

First Author Publications:

Howe CJ, Cole SR, Lau B, Napravnik S, Eron JJ. Selection bias due to loss to follow up in cohort studies. Epidemiology. 2015 Oct 19. [Epub ahead of print]. 

Howe CJ, Cain LE, Hogan JW. Are all biases missing data problems? Curr Epidemiol Rep. 2015 Sept; 2:162–171. doi 10.1007/s40471-015-0050-8

Howe CJ, Napravnik S, Cole SR, Kaufman JS, Adimora AA, Elston B, Eron JJ, Mugavero MJ. African American race and HIV virologic suppression: beyond disparities in clinic attendance. Am J. Epidemiol. 2014 Jun 15;179(12):1484-92. doi: 10.1093/aje/kwu069. Epub 2014 May 8.

Howe CJ, Cole SR, Napravnik S, Kaufman JS, Adimora AA, Elston B, Eron JJ, Mugavero MJ. The role of at-risk alcohol/drug use and treatment in appointment attendance and virologic suppression among HIV+ African Americans. AIDS Res Hum Retroviruses. 2014 Mar;30(3):233-40.

Howe CJ, Cole SR, Mehta SH, Kirk GD. Estimating the effects of multiple time-varying exposures using joint marginal structural models: alcohol consumption, injection drug use, and HIV acquisition. Epidemiology. 2012 Jul;23(4):574-82. Erratum in: Epidemiology. 2015 Jul;26(4):623.

Howe CJ, Cole SR, Ostrow DG, Mehta SH, Kirk GD. A prospective study of alcohol consumption and HIV acquisition among injection drug users. AIDS. 2011 Jan 14;25(2):221-8.

Howe CJ, Cole SR, Chmiel JS, Muñoz A. Limitation of inverse probability-of-censoring weights in estimating survival in the presence of strong selection bias. Am J Epidemiol. 2011 Mar 1;173(5):569-77.

Howe CJ, Cole SR, Westreich DJ, Greenland S, Napravnik S, Enron JJ. Splines for trend analysis and continuous confounder control. Epidemiology. 2011 Nov; 22(6): 874-875.

Howe CJ, Cole SR, Napravnik S, Eron JJ. Enrollment, retention, and visit attendance in the University of North Carolina Center for AIDS Research HIV clinical cohort, 2001-2007. AIDS Res Hum Retroviruses. 2010 Aug;26(8):875-81.

Howe CJ, Sander PM, Plankey MW, Cole SR. Effects of time-varying exposures adjusting for time-varying confounders: The case of alcohol consumption and risk of incident human immunodeficiency virus infection. Int J Public Health. 2010 Jun; 55(3):227-228.

Howe CJ, Fuller CM, Ompad DC, Galea S, Koblin B, Thomas D, Vlahov D. Association of sex, hygiene and drug equipment sharing with hepatitis C virus infection among non-injecting drug users in New York City. Drug Alcohol Depend. 2005 Sep 1;79(3):389-95.


Co-author Publications:

Merchant AT, Georgantopoulos P, Howe CJ, Virani SS, Morales DA, Haddock SK. Effect of long term periodontal care on hemoglobin A1c in individuals with type 2 diabetes. Journal of Dental Research. In Press.

Loucks EB, Britton WB, Howe CJ, Gutman R, Gilman SG, Brewer J, Eaton CB, Buka SL. Associations of dispositional mindfulness with obesity and central adiposity: The New England Family Study. Int J Behav Med. 2015 Oct 19. [Epub ahead of print].

Loucks EB, Britton WB, Howe CJ, Eaton CB, Buka SL. Positive associations of mindfulness with cardiovascular health: The New England Family Study. Int J Behav Med. 2015 Aug;22(4):540-50. doi: 10.1007/s12529-014-9448-9.

Loucks EB, Gilman SE, Howe CJ, Kawachi I, Kubzanksy LD, Rudd RE, Martin LT, Nandi A, Wilhelm A, Buka SL. Education and coronary heart disease risk: potential mechanisms such as literacy, perceived constraint and depressive symptoms. Health Educ Behav. 2015 Jun;42(3):370-9. doi: 10.1177/1090198114560020. Epub 2014 Nov 27.

Gebrekristos HT, Howe CJ. Ratio of observed and expected joint effects. Epidemiology. 2015 Jan;26(1):e3-e4.

Kinnard EN, Howe CJ, Kerr T, Hass VS, Marshall BDL. Self-reported changes in drug use behaviors and syringe disposal methods following the opening of a supervised injecting facility in Copenhagen, Denmark. Harm Reduct J. 2014 Oct 28; 11(1):29. doi: 10.1186/1477-7517-11-29.

Braun JM, Lanphear BP, Calafat AM, Deria S, Khoury J, Howe CJ, Venners SA. Early-life Bisphenol A exposure and child body mass index: A prospective cohort study. Environ Health Perspect. 2014 Nov; 122(11):1239-1245. doi: Epub 2014 Jul 29.

Sahlu I, Howe CJ, Clark MA, Marshall BDL. HIV status, knowledge of mother-to-child transmission of HIV and antenatal care use among Ethiopian women. J Epidemiol Glob Health. 2014 Sep;4(3):177-184. doi: 10.1016/j.jegh.2014.01.001. Epub 2014 Feb 13.

Escudero DJ, Lurie MN, Kerr T, Howe CJ, Marshall BDL. HIV Pre-exposure prophylaxis (PrEP) for people who inject drugs: A systematic review and agenda for future research. J Int AIDS Soc. 2014 Mar 27;17(1):18899.

Naimi AI, Kaufman JS, Howe CJ, Robinson WR. Mediation considerations: serum potassium and the racial disparity in diabetes risk. Am J Clin Nutr. 2011 Aug;94(2):614-6.

Smith LB, Fadrowski JJ, Howe CJ, Fivush BA, Neu AM, Furth SL. Secondary hyperparathyroidism and anemia in children treated by hemodialysis. Am J Kidney Dis. 2010 Feb;55(2):326-34.

research overview

Dr. Howe's research interests include better characterizing, adapting, and applying advanced quantitative methods to enhance causal inference based on data from experimental and observational studies. Specifically, her work has focused on using advanced causal inference techniques to address selection bias, confounding bias, and to perform mediation analyses largely when examining the link between alcohol/drug use and HIV as well as the sources of HIV disparities. Dr. Howe has collaborated with researchers at Brown and elsewhere in the areas of infectious disease, cardiovascular, environmental, and social epidemiology.

funded research

PCORI (K. Robison, PI)

July 2015 to June 2018
Cancer of the Uterus and Treatment of Stress Urinary Incontinence
Role: Co-investigator

R03 DE022785 (A. Merchant, PI)
April 2013 to March 2016
Marginal structural models to get periodontal treatment effects on A1C in diabetes
Role: Co-investigator

U24 AA022003 (C. Kahler, PI)
September 2012 to August 2016
Mechanisms of Behavior Change Resource Core for Alcohol-HIV Interventions
Role: Co-investigator

K22 AI095021 (C. Howe, PI)
February 2012 to July 2014
Missed visits and virologic failure among HIV infected African Americans receiving medical care

R01 AA017594 (S. Cole, PI)
June 2009 to July 2011
Structural models and direct and indirect effects of alcohol use on HIV infection
Role: Post Doctoral Research Associate

F31 DA022114 (C. Howe, PI)
September 2006 to June 2009
Methods for informative censoring in HIV/AIDS cohorts