Dr. Duan obtained his PhD in Biostatistics from Yale University in 2005. He joined the faculty in the Department of Biostatistics and Center for Statistical Sciences at Brown University in 2008. He is primarily working in the Biostatistics Center of ECOG-ACRIN and conducting clinical cancer research to explore the role of medical imaging and image-guided therapy in the diagnosis and treatment of cancer. His research interests include high-throughput data analysis, bioinformatics, diagnostic test and biomarker evaluation and radio(geno)mics.
| Peikert T, Duan F, Rajagopalan S, Karwoski RA, Clay R, Robb RA, Qin Z, Sicks J, Bartholmai BJ, Maldonado F. "Correction: Novel high-resolution computed tomography-based radiomic classifier for screen-identified pulmonary nodules in the National Lung Screening Trial." PLoS ONE, vol. 13, no. 10, 2018, pp. e0205311. |
| Gareen IF, Hillner BE, Hanna L, Makineni R, Duan F, Shields AF, Subramaniam RM, Siegel BA. "Hospice Admission and Survival After <sup>18</sup>F-Fluoride PET Performed for Evaluation of Osseous Metastatic Disease in the National Oncologic PET Registry." Journal of Nuclear Medicine, vol. 59, no. 3, 2018, pp. 427-433. |
| Peikert, Tobias, Duan, Fenghai, Rajagopalan, Srinivasan, Karwoski, Ronald A., Clay, Ryan, Robb, Richard A., Qin, Ziling, Sicks, JoRean, Bartholmai, Brian J., Maldonado, Fabien. "Novel high-resolution computed tomography-based radiomic classifier for screen-identified pulmonary nodules in the National Lung Screening Trial." PLOS ONE, vol. 13, no. 5, 2018, pp. e0196910. |
| Andriole GL, Kostakoglu L, Chau A, Duan F, Mahmood U, Mankoff DA, Schuster DM, Siegel BA, LOCATE study group. "The Impact of Positron Emission Tomography with <sup>18</sup>F-Fluciclovine on the Management of Patients with Biochemical Recurrence of Prostate Cancer: Results from the LOCATE Trial." The Journal of Urology, 2018. |
| Duan, Fenghai, Xu, Ye. "Applying Multivariate Adaptive Splines to Identify Genes With Expressions Varying After Diagnosis in Microarray Experiments." Cancer Informatics, vol. 16, no. 0, 2017. |
| Hillner BE, Hanna L, Makineni R, Duan F, Shields AF, Subramaniam RM, Gareen I, Siegel BA. "Intended Versus Inferred Treatment After <sup>18</sup>F-Fluoride PET Performed for Evaluation of Osseous Metastatic Disease in the National Oncologic PET Registry." Journal of Nuclear Medicine, vol. 59, no. 3, 2017, pp. 421-426. |
| Gierada DS, Pinsky PF, Duan F, Garg K, Hart EM, Kazerooni EA, Nath H, Watts JR Jr, Aberle DR. "Interval lung cancer after a negative CT screening examination: CT findings and outcomes in National Lung Screening Trial participants." European Radiology, vol. 27, no. 8, 2017, pp. 3249-3256. |
| Salavati A, Duan F, Snyder BS, Wei B, Houshmand S, Khiewvan B, Opanowski A, Simone CB 2nd, Siegel BA, Machtay M, Alavi A. "Optimal FDG PET/CT volumetric parameters for risk stratification in patients with locally advanced non-small cell lung cancer: results from the ACRIN 6668/RTOG 0235 trial." European Journal of Nuclear Medicine and Molecular Imaging, vol. 44, no. 12, 2017, pp. 1969-1983. |
| Bazan, Jose G., Duan, Fenghai, Snyder, Bradley S., Horng, Dunstan, Graves, Edward E., Siegel, Barry A., Machtay, Mitchell, Loo, Billy W. "Metabolic tumor volume predicts overall survival and local control in patients with stage III non-small cell lung cancer treated in ACRIN 6668/RTOG 0235." European Journal of Nuclear Medicine and Molecular Imaging, vol. 44, no. 1, 2016, pp. 17-24. |
| Ohri N, Duan F, Snyder BS, Wei B, Machtay M, Alavi A, Siegel BA, Johnson DW, Bradley JD, DeNittis A, Werner-Wasik M, El Naqa I. "Pretreatment 18F-FDG PET Textural Features in Locally Advanced Non-Small Cell Lung Cancer: Secondary Analysis of ACRIN 6668/RTOG 0235." Journal of Nuclear Medicine, vol. 57, no. 6, 2016, pp. 842-8. |
| Hillner, B. E., Siegel, B. A., Hanna, L., Duan, F., Quinn, B., Shields, A. F. "18F-fluoride PET used for treatment monitoring of systemic cancer therapy: results from the National Oncologic PET Registry." Journal of Nuclear Medicine, vol. 56, no. 2, 2015, pp. 222-228. |
| Young, Robert P., Duan, Fenghai, Chiles, Caroline, Hopkins, Raewyn J., Gamble, Greg D., Greco, Erin M., Gatsonis, Constantine, Aberle, Denise. "Airflow Limitation and Histology Shift in the National Lung Screening Trial. The NLST-ACRIN Cohort Substudy." Am J Respir Crit Care Med, vol. 192, no. 9, 2015, pp. 1060-1067. |
| Chiles C, Duan F, Gladish GW, Ravenel JG, Baginski SG, Snyder BS, DeMello S, Desjardins SS, Munden RF, NLST Study Team. "Association of Coronary Artery Calcification and Mortality in the National Lung Screening Trial: A Comparison of Three Scoring Methods." Radiology, vol. 276, no. 1, 2015, pp. 82-90. |
| Ohri, N., Duan, F., Machtay, M., Gorelick, J. J., Snyder, B. S., Alavi, A., Siegel, B. A., Johnson, D. W., Bradley, J. D., DeNittis, A., Werner-Wasik, M. "Pretreatment FDG-PET Metrics in Stage III Non-Small Cell Lung Cancer: ACRIN 6668/RTOG 0235." JNCI Journal of the National Cancer Institute, vol. 107, no. 4, 2015, pp. djv004-djv004. |
| Markovina S, Duan F, Snyder BS, Siegel BA, Machtay M, Bradley JD. "Regional Lymph Node Uptake of [(18)F]Fluorodeoxyglucose After Definitive Chemoradiation Therapy Predicts Local-Regional Failure of Locally Advanced Non-Small Cell Lung Cancer: Results of ACRIN 6668/RTOG 0235." International Journal of Radiation Oncology*Biology*Physics, vol. 93, no. 3, 2015, pp. 597-605. |
| Zhang Z, Wang Y, Duan F. "An AUC-like index for agreement assessment." Journal of biopharmaceutical statistics, vol. 24, no. 4, 2014, pp. 893-907. |
| Hillner BE, Siegel BA, Hanna L, Duan F, Shields AF, Coleman RE. "Impact of 18F-fluoride PET in patients with known prostate cancer: initial results from the National Oncologic PET Registry." Journal of Nuclear Medicine, vol. 55, no. 4, 2014, pp. 574-81. |
| Hillner BE, Siegel BA, Hanna L, Duan F, Shields AF, Quinn B, Coleman RE. "Impact of 18F-Fluoride PET on Intended Management of Patients with Cancers Other Than Prostate Cancer: Results from the National Oncologic PET Registry." Journal of Nuclear Medicine, vol. 55, no. 7, 2014, pp. 1054-1061. |
| Gareen IF, Duan F, Greco EM, Snyder BS, Boiselle PM, Park ER, Fryback D, Gatsonis C. "Impact of lung cancer screening results on participant health-related quality of life and state anxiety in the National Lung Screening Trial." Cancer, vol. 120, no. 21, 2014, pp. 3401-9. |
| Ohri, N., Duan, F., Machtay, M., Gorelick, J.J., Snyder, B.S., Alavi, A., Siegel, B., Johnson, D.W., Bradley, J.D., DeNittis, A.S., Werner-Wasik, M. "Metabolic Tumor Volume on FDG-PET Predicts Clinical Outcomes Following Chemoradiation Therapy for Locally Advanced Non-Small Cell Lung Cancer: A Secondary Analysis of ECOG-ACRIN 6668/RTOG 0235." International Journal of Radiation Oncology*Biology*Physics, vol. 90, no. 5, 2014, pp. S17. |
| Ohri, N., Duan, F., Machtay, M., Gorelick, J.J., Snyder, B.S., Alavi, A., Siegel, B., Johnson, D.W., Bradley, J.D., DeNittis, A.S., Werner-Wasik, M. "Metabolic Tumor Volume on FDG-PET Predicts Clinical Outcomes Following Chemoradiation Therapy for Locally-Advanced Non-small Cell Lung Cancer: A Secondary Analysis of ECOG-ACRIN 6668 / RTOG 0235." International Journal of Radiation Oncology*Biology*Physics, vol. 90, no. 1, 2014, pp. S144-S145. |
| Bazan, J.G., Duan, F., Snyder, B.S., Horng, D., Graves, E.E., Siegel, B.A., Machtay, M., Loo, B.W. "Metabolic Tumor Volume Predicts Overall Survival in Patients With Stage III Non-Small Cell Lung Cancer Treated on ACRIN 6668/RTOG 0235." International Journal of Radiation Oncology*Biology*Physics, vol. 90, no. 5, 2014, pp. S3-S4. |
| Machtay M, Siegel BA, Duan F, Snyder BS. "Reply to J.-S. Ryu et al and A.T. Berman et al." Journal of Clinical Oncology, vol. 32, no. 15, 2014, pp. 1632-3. |
| Markovina, S., Duan, F., Snyder, B.J., Siegel, B.A., Machtay, M., Bradley, J.D. "Residual Post-Treatment FDG Avidity in Regional Lymph Nodes Impacts Local-Regional Control in Patients Receiving Definitive Chemoradiation for Non-small Cell Lung Cancer: A Secondary Analysis of ACRIN 6668/RTOG 0235." International Journal of Radiation Oncology*Biology*Physics, vol. 90, no. 1, 2014, pp. S144. |
| Park ER, Gareen IF, Jain A, Ostroff JS, Duan F, Sicks JD, Rakowski W, Diefenbach M, Rigotti NA. "Examining whether lung screening changes risk perceptions: National Lung Screening Trial participants at 1-year follow-up." Cancer, vol. 119, no. 7, 2013, pp. 1306-13. |
| Machtay M, Duan F, Siegel BA, Snyder BS, Gorelick JJ, Reddin JS, Munden R, Johnson DW, Wilf LH, DeNittis A, Sherwin N, Cho KH, Kim SK, Videtic G, Neumann DR, Komaki R, Macapinlac H, Bradley JD, Alavi A. "Prediction of survival by [18F]fluorodeoxyglucose positron emission tomography in patients with locally advanced non-small-cell lung cancer undergoing definitive chemoradiation therapy: results of the ACRIN 6668/RTOG 0235 trial." Journal of Clinical Oncology, vol. 31, no. 30, 2013, pp. 3823-30. |
| National Lung Screening Trial Research Team, Church TR, Black WC, Aberle DR, Berg CD, Clingan KL, Duan F, Fagerstrom RM, Gareen IF, Gierada DS, Jones GC, Mahon I, Marcus PM, Sicks JD, Jain A, Baum S. "Results of initial low-dose computed tomographic screening for lung cancer." New England Journal of Medicine, vol. 368, no. 21, 2013, pp. 1980-91. |
| Aberle DR, DeMello S, Berg CD, Black WC, Brewer B, Church TR, Clingan KL, Duan F, Fagerstrom RM, Gareen IF, Gatsonis CA, Gierada DS, Jain A, Jones GC, Mahon I, Marcus PM, Rathmell JM, Sicks J, National Lung Screening Trial Research Team. "Results of the two incidence screenings in the National Lung Screening Trial." New England Journal of Medicine, vol. 369, no. 10, 2013, pp. 920-31. |
| Duan F, Smith LM, Gustafson DM, Zhang C, Dunlevy MJ, Gastier-Foster JM, Barr FG. "Genomic and clinical analysis of fusion gene amplification in rhabdomyosarcoma: a report from the Children's Oncology Group." Genes, chromosomes & cancer, vol. 51, no. 7, 2012, pp. 662-74. |
| Hillner BE, Siegel BA, Hanna L, Shields AF, Duan F, Gareen IF, Quinn B, Coleman RE. "Impact of 18F-FDG PET used after initial treatment of cancer: comparison of the National Oncologic PET Registry 2006 and 2009 cohorts." Journal of Nuclear Medicine, vol. 53, no. 5, 2012, pp. 831-7. |
| Liu L, Yannam GR, Nishikawa T, Yamamoto T, Basma H, Ito R, Nagaya M, Dutta-Moscato J, Stolz DB, Duan F, Kaestner KH, Vodovotz Y, Soto-Gutierrez A, Fox IJ. "The microenvironment in hepatocyte regeneration and function in rats with advanced cirrhosis." Hepatology, vol. 55, no. 5, 2012, pp. 1529-39. |
| Machtay, M., Duan, F., Snyder, B., Gorelick, J., DeNittis, A.S., Chiles, C., Mahon, I., Alavi, A., Siegel, B.A., Bradley, J.D. "Can Tumor FDG-PET Scan Uptake (SUV) Predict Local Control in Stage III NSCLC? Preliminary Results from ACRIN 6668/RTOG 0235." International Journal of Radiation Oncology*Biology*Physics, vol. 81, no. 2, 2011, pp. S134-S135. |
| Reichek JL, Duan F, Smith LM, Gustafson DM, O'Connor RS, Zhang C, Dunlevy MJ, Gastier-Foster JM, Barr FG. "Genomic and clinical analysis of amplification of the 13q31 chromosomal region in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group." Clin Cancer Res , vol. 17, no. 6, 2011, pp. 1463-73. |
| Hillner BE, Siegel BA, Shields AF, Duan F, Gareen IF, Hanna L, Coleman RE. "Impact of dedicated brain PET on intended patient management in participants of the national oncologic PET Registry." Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, vol. 13, no. 1, 2011, pp. 161-5. |
| National Lung Screening Trial Research Team, Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, Gareen IF, Gatsonis C, Marcus PM, Sicks JD. "Reduced lung-cancer mortality with low-dose computed tomographic screening." New England Journal of Medicine, vol. 365, no. 5, 2011, pp. 395-409. |
| Duan F, Pauley MA, Spindel ER, Zhang L, Norgren RB Jr. "Large scale analysis of positional effects of single-base mismatches on microarray gene expression data." BioData mining, vol. 3, no. 1, 2010, pp. 2. |
| Patz EF Jr, Caporaso NE, Dubinett SM, Massion PP, Hirsch FR, Minna JD, Gatsonis C, Duan F, Adams A, Apgar C, Medina RM, Aberle DR. "National Lung Cancer Screening Trial American College of Radiology Imaging Network Specimen Biorepository originating from the Contemporary Screening for the Detection of Lung Cancer Trial (NLST, ACRIN 6654): design, intent, and availability of specimens for validation of lung cancer biomarkers." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, vol. 5, no. 10, 2010, pp. 1502-6. |
| Coleman RE, Hillner BE, Shields AF, Duan F, Merlino DA, Hanna LG, Stine SH, Siegel BA. "PET and PET/CT reports: observations from the National Oncologic PET Registry." Journal of Nuclear Medicine, vol. 51, no. 1, 2010, pp. 158-63. |
| Wiederin J, Rozek W, Duan F, Ciborowski P. "Biomarkers of HIV-1 associated dementia: proteomic investigation of sera." Proteome science, vol. 7, 2009, pp. 8. |
| García, K., García, V., Pérez Laspiur, J., Duan, F., Meléndez, L.M. "Characterization of the Placental Macrophage Secretome: Implications for Antiviral Activity." Placenta, vol. 30, no. 2, 2009, pp. 149-155. |
| Barr FG, Duan F, Smith LM, Gustafson D, Pitts M, Hammond S, Gastier-Foster JM. "Genomic and clinical analyses of 2p24 and 12q13-q14 amplification in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group." Genes, chromosomes & cancer, vol. 48, no. 8, 2009, pp. 661-72. |
| Toro-Nieves, Dm, Rodriguez, Y, Plaud, M, Ciborowski, P, Duan, F, Laspiur, J Pérez, Wojna, V, Meléndez, LM. "Proteomic analyses of monocyte-derived macrophages infected with human immunodeficiency virus type 1 primary isolates from Hispanic women with and without cognitive impairment." J Neurovirol, vol. 15, no. 1, 2009, pp. 36-50. |
| Chaudhuri A, Duan F, Morsey B, Persidsky Y, Kanmogne GD. "HIV-1 activates proinflammatory and interferon-inducible genes in human brain microvascular endothelial cells: putative mechanisms of blood-brain barrier dysfunction." Journal of Cerebral Blood Flow & Metabolism, vol. 28, no. 4, 2008, pp. 697-711. |
| Buescher JL, Duan F, Sun J, Price RW, Ikezu T. "OTK18 Levels in Plasma and Cerebrospinal Fluid Correlate with Viral Load and CD8 T-cells in Normal and AIDS Patients." Journal of Neuroimmune Pharmacology, vol. 3, no. 4, 2008, pp. 230-235. |
| Garcia, Katia, Garcia, Vivian, Perez, Juliana, Duan, Fenghai, Melendez, Loyda. "Placental and Monocyte-derived Macrophages have Different Secretome." Antiviral Research, vol. 78, no. 2, 2008, pp. A39. |
| Luciano-Montalvo, C., Ciborowski, P., Duan, F., Gendelman, H.E., Meléndez, L.M. "Proteomic Analyses Associate Cystatin B with Restricted HIV-1 Replication in Placental Macrophages." Placenta, vol. 29, no. 12, 2008, pp. 1016-1023. |
| Berro, A.I., Sugiura, H., Liu, X., Duan, F., Kawasaki, S., Togo, S., Kamio, K., Wang, X.Q., Mao, L., Ahn, Y., Ertl, R.F., Casale, T.B., Rennard, S.I. "Airway Fibroblasts Isolated from Mouse Model of Allergic Asthma Display Distinct Cellular and Phenotypic Characteristics as Compared to Normal Fibroblasts." Journal of Allergy and Clinical Immunology, vol. 119, no. 1, 2007, pp. S301. |
| Laspiur JP, Anderson ER, Ciborowski P, Wojna V, Rozek W, Duan F, Mayo R, Rodríguez E, Plaud-Valentín M, Rodríguez-Orengo J, Gendelman HE, Meléndez LM. "CSF proteomic fingerprints for HIV-associated cognitive impairment." Journal of Neuroimmunology, vol. 192, no. 1-2, 2007, pp. 157-70. |
| Sugiura, Hisatoshi, Liu, Xiangde, Duan, Fenghai, Kawasaki, Shin, Togo, Shinsaku, Kamio, Koichiro, Wang, Xing Qi, Mao, Lijun, Ahn, Youngsoo, Ertl, Ronald F., Bargar, Tom W., Berro, Abdo, Casale, Thomas B., Rennard, Stephen I. "Cultured Lung Fibroblasts from Ovalbumin-Challenged “Asthmatic” Mice Differ Functionally from Normal." American Journal of Respiratory Cell and Molecular Biology, vol. 37, no. 4, 2007, pp. 424-430. |
| Duan F, Spindel ER, Li YH, Norgren RB Jr. "Intercenter reliability and validity of the rhesus macaque GeneChip." BMC genomics, vol. 8, 2007, pp. 61. |
| Liao, Jason J. Z., Duan, Fenghai. "Calibrating the concentration from a serial dilution process." J. Chemometrics, vol. 20, no. 6-7, 2006, pp. 294-301. |
| Duan F, Zhang H. "Correcting the loss of cell-cycle synchrony in clustering analysis of microarray data using weights." Bioinformatics, vol. 20, no. 11, 2004, pp. 1766-71. |
Dr. Duan's research interests include high-throughput data analysis, bioinformatics, diagnostic test and biomarker evaluation and radio(geno)mics.
Dr. Duan's research work can be summarized into two categories: methodological research and multidisciplinary research. His methodological research advances the statistical science in the areas of bioinformatics, machine learning, reliability assessment, diagnostic test and marker evaluations in biomedical research. His early multidisciplinary research focuses on the cancer signature’s discovery through the data analysis of various high-throughput experiments for genomics, proteomics, genome amplification studies. Recently, Dr. Duan mainly collaborates with investigators from ECOG-ACRIN to run the clinical trials guided by the advanced medical imaging, which advances the clinical science on oncology research, particularly lung cancer (LC) research. In addition, motivated by his collaborative research on various lung cancer studies, Dr. Duan is developing a research line to combine the imaging and molecular markers in the lung cancer’s risk prediction modeling (e.g., radiogenomics in lung cancers for high-dimensional markers). Currently, he is the lead statistician for a number of ECOG-ACRIN and DECAMP clinical trials, varying across different cancer types and imaging modailities. Aside from the ACRIN studies, Dr. Duan is the statistician for the National Oncologic PET Registry (NOPR), a nationwide prospective internet-based registry with the primary goal of assessing the effect of PET on referring physicians’ plans of intended patient management. Dr. Duan has publications on the journals of New England Journal of Medicine, Journal of Clinical Oncology, Radiology, Journal of Nuclear Medicine, Clinical Cancer Research, Bioinformatics, BMC Genomics, and so on.
ONGOING RESEARCH SUPPORT
2U10 CA180794 (Gray and Gatsonis) 04/29/14-02/28/25 3.00 calendar
NCI/Dana Farber Cancer Institute $9,254,000
ECOG-ACRIN Network Group Statistics and Data Management Center (Statistical Core subaward #1800006)
This subcontract covers support for the operations of Brown office of the Statistics and Data Management Center (SDMC) of ECOG-ACRIN Cancer Research Group. The SDMC is organized and operated jointly by the Department of Biostatistics and Computational Biology at the Dana-Farber Cancer Institute (DFCI), the Department of Biostatistics at Brown University, the Frontier Science and Technology Research Foundation (FSTRF) and the American College of Radiology (ACR), under the direction of the Group Statisticians.
Role: Faculty Statistician
2UG1CA189828-06-BRWN3 (Schnall, Sub PI Gatsonis) 08/01/17-07/31/25 0.60 calendar
EAMRF/NCI $10,291,710
ECOG-ACRIN Tomosynthesis Mammographic Imaging Screening Trial (TMIST)
The project lead and team will assist with the oversight and implementation of TIST; preparation of protocol and data collection forms; NCI review, study opening, monitoring of accrual and data quality; data cleaning and analysis; performance of interim and final data analyses; preparation of reports to the study team and Data Safety Monitoring Committee; preparation of manuscripts; addressing methodologic issues as they arise in the design and conduct of the study; development of statistical methodology for the evaluation of imaging.
Role: Faculty Statistician
1R02518031 CA (Specht) 07/15/2021-06/30/2026 0.90 calendar
NIH/EAMRF $409,346
Role of ctDNA changes as a response measure in the EA1183 patient population and how ctDNA changes correlate with metabolic response by serial FDG PET/CT
This subcontract provides support for operating a Biostatistics Core for the EA1183 substudy to evaluate the performance of using circulating DNA (ctDNA) to predict progression-free survival/time to SRE/overall survival, and the temporal association between the change in ctDNA and time of clinical or radiographic progression of disease in patients with bone-dominant metastatic breast cancer.
Role: Co-Investigator
1R01 CA261752 (Zebrack, Sub PI: Duan) 07/01/21-06/30/26 0.90 calendar
NCI/ Regents of the University of Michigan $1,532,384 effort begins 09/01/21
Social Genomic Mechanisms of Health Disparities among Adolescent and Young Adult (AYA) Cancer Survivors
The proposed study intends to identify and define functional genomic pathways through which psychosocial and social environmental risk and resilience factors influence gene regulation in AYAs, and thus contribute to a greater understanding of health disparities in post-treatment survivorship.
R01 (Sadigh, Sub PI: Duan) 08/01/22-07/31/27 1.20 calendar
NCI/Emory University $955,099 effort starts 08/01/22
Improving medication adherence using a CONnected CUstomized Treatment Platform (CONCURxP)
This project intends to test an mHealth intervention to improve Palbociclib adherence by conducting a randomized controlled trial (RCT) of a CONnected CUstomized Treatment Platform (CONCURxP) vs. enhanced usual care.
R01 AG079241-01 (Alber, Sub PI: Duan) 09/15/2022 – 08/31/2027 1.20 calendar
National Institute on Aging/ University of Rhode Island $677,532
Longitudinal validation of retinal biomarkers against cerebral biomarkers in the Atlas of Retinal Imaging in Alzheimer's Study (ARIAS)
This subcontract provides support for establishing and operating a Biostatistics Core for the proposed study in response to a R01 opportunity “Research on Current Topics in Alzheimer's Disease and Its Related Dementias”. The objective of this study is to develop a multi-site, longitudinal study to validate retinal biomarkers of Alzheimer's disease against reference standard brain imaging biomarkers (amyloid PET, MRI).
R01 (Sadigh, Sub PI: Duan) 12/01/22-11/30/27 1.20 calendar
Emory/NCI $1,110,813
Effectiveness of Out-of-Pocket Cost COMmunication and Financial Navigation (CostCOM) in Cancer patients
We propose a hybrid effectiveness-implementation study of OOP Cost COMmunication and financial navigation (CostCOM intervention) vs. enhanced usual care in 1200 newly diagnosed cancer patients from 24 community cancer clinics using a design, where sites are randomized sequentially to initiate the intervention.
| Name | Title |
|---|---|
| Gareen, Ilana | Associate Professor of Epidemiology (Research) |
| Gatsonis, Constantine | Henry Ledyard Goddard University Professor of Statistical Sciences, Director of the Center for Statistical Sciences |
| Steingrimsson, Jon | Associate Professor of Biostatistics |
Professional Societies
American Statistical Association
International Biometric Society, Eastern North American Region
International Chinese Statistical Association
Editorial board
Journal of Molecular Diagnostics
Scientific Reports
