Dr. Duan obtained his PhD in Biostatistics from Yale University in 2005. He joined the faculty in the Department of Biostatistics and Center for Statistical Sciences at Brown University in 2008. He is primarily working in the Biostatistics Center of ECOG-ACRIN and conducting clinical cancer research to explore the role of medical imaging and image-guided therapy in the diagnosis and treatment of cancer. His research interests include high-throughput data analysis, bioinformatics, diagnostic test and biomarker evaluation and radio(geno)mics.
| Peikert T, Duan F, Rajagopalan S, Karwoski RA, Clay R, Robb RA, Qin Z, Sicks J, Bartholmai BJ, Maldonado F. "Correction: Novel high-resolution computed tomography-based radiomic classifier for screen-identified pulmonary nodules in the National Lung Screening Trial." PLoS ONE, vol. 13, no. 10, 2018, pp. e0205311. |
| Gareen IF, Hillner BE, Hanna L, Makineni R, Duan F, Shields AF, Subramaniam RM, Siegel BA. "Hospice Admission and Survival After <sup>18</sup>F-Fluoride PET Performed for Evaluation of Osseous Metastatic Disease in the National Oncologic PET Registry." Journal of Nuclear Medicine, vol. 59, no. 3, 2018, pp. 427-433. |
| Peikert, Tobias, Duan, Fenghai, Rajagopalan, Srinivasan, Karwoski, Ronald A., Clay, Ryan, Robb, Richard A., Qin, Ziling, Sicks, JoRean, Bartholmai, Brian J., Maldonado, Fabien. "Novel high-resolution computed tomography-based radiomic classifier for screen-identified pulmonary nodules in the National Lung Screening Trial." PLOS ONE, vol. 13, no. 5, 2018, pp. e0196910. |
| Andriole GL, Kostakoglu L, Chau A, Duan F, Mahmood U, Mankoff DA, Schuster DM, Siegel BA, LOCATE study group. "The Impact of Positron Emission Tomography with <sup>18</sup>F-Fluciclovine on the Management of Patients with Biochemical Recurrence of Prostate Cancer: Results from the LOCATE Trial." The Journal of Urology, 2018. |
| Duan, Fenghai, Xu, Ye. "Applying Multivariate Adaptive Splines to Identify Genes With Expressions Varying After Diagnosis in Microarray Experiments." Cancer Informatics, vol. 16, no. 0, 2017. |
| Hillner BE, Hanna L, Makineni R, Duan F, Shields AF, Subramaniam RM, Gareen I, Siegel BA. "Intended Versus Inferred Treatment After <sup>18</sup>F-Fluoride PET Performed for Evaluation of Osseous Metastatic Disease in the National Oncologic PET Registry." Journal of Nuclear Medicine, vol. 59, no. 3, 2017, pp. 421-426. |
| Gierada DS, Pinsky PF, Duan F, Garg K, Hart EM, Kazerooni EA, Nath H, Watts JR Jr, Aberle DR. "Interval lung cancer after a negative CT screening examination: CT findings and outcomes in National Lung Screening Trial participants." European Radiology, vol. 27, no. 8, 2017, pp. 3249-3256. |
| Salavati A, Duan F, Snyder BS, Wei B, Houshmand S, Khiewvan B, Opanowski A, Simone CB 2nd, Siegel BA, Machtay M, Alavi A. "Optimal FDG PET/CT volumetric parameters for risk stratification in patients with locally advanced non-small cell lung cancer: results from the ACRIN 6668/RTOG 0235 trial." European Journal of Nuclear Medicine and Molecular Imaging, vol. 44, no. 12, 2017, pp. 1969-1983. |
| Bazan, Jose G., Duan, Fenghai, Snyder, Bradley S., Horng, Dunstan, Graves, Edward E., Siegel, Barry A., Machtay, Mitchell, Loo, Billy W. "Metabolic tumor volume predicts overall survival and local control in patients with stage III non-small cell lung cancer treated in ACRIN 6668/RTOG 0235." European Journal of Nuclear Medicine and Molecular Imaging, vol. 44, no. 1, 2016, pp. 17-24. |
| Ohri N, Duan F, Snyder BS, Wei B, Machtay M, Alavi A, Siegel BA, Johnson DW, Bradley JD, DeNittis A, Werner-Wasik M, El Naqa I. "Pretreatment 18F-FDG PET Textural Features in Locally Advanced Non-Small Cell Lung Cancer: Secondary Analysis of ACRIN 6668/RTOG 0235." Journal of Nuclear Medicine, vol. 57, no. 6, 2016, pp. 842-8. |
| Hillner, B. E., Siegel, B. A., Hanna, L., Duan, F., Quinn, B., Shields, A. F. "18F-fluoride PET used for treatment monitoring of systemic cancer therapy: results from the National Oncologic PET Registry." Journal of Nuclear Medicine, vol. 56, no. 2, 2015, pp. 222-228. |
| Young, Robert P., Duan, Fenghai, Chiles, Caroline, Hopkins, Raewyn J., Gamble, Greg D., Greco, Erin M., Gatsonis, Constantine, Aberle, Denise. "Airflow Limitation and Histology Shift in the National Lung Screening Trial. The NLST-ACRIN Cohort Substudy." Am J Respir Crit Care Med, vol. 192, no. 9, 2015, pp. 1060-1067. |
| Chiles C, Duan F, Gladish GW, Ravenel JG, Baginski SG, Snyder BS, DeMello S, Desjardins SS, Munden RF, NLST Study Team. "Association of Coronary Artery Calcification and Mortality in the National Lung Screening Trial: A Comparison of Three Scoring Methods." Radiology, vol. 276, no. 1, 2015, pp. 82-90. |
| Ohri, N., Duan, F., Machtay, M., Gorelick, J. J., Snyder, B. S., Alavi, A., Siegel, B. A., Johnson, D. W., Bradley, J. D., DeNittis, A., Werner-Wasik, M. "Pretreatment FDG-PET Metrics in Stage III Non-Small Cell Lung Cancer: ACRIN 6668/RTOG 0235." JNCI Journal of the National Cancer Institute, vol. 107, no. 4, 2015, pp. djv004-djv004. |
| Markovina S, Duan F, Snyder BS, Siegel BA, Machtay M, Bradley JD. "Regional Lymph Node Uptake of [(18)F]Fluorodeoxyglucose After Definitive Chemoradiation Therapy Predicts Local-Regional Failure of Locally Advanced Non-Small Cell Lung Cancer: Results of ACRIN 6668/RTOG 0235." International Journal of Radiation Oncology*Biology*Physics, vol. 93, no. 3, 2015, pp. 597-605. |
| Zhang Z, Wang Y, Duan F. "An AUC-like index for agreement assessment." Journal of biopharmaceutical statistics, vol. 24, no. 4, 2014, pp. 893-907. |
| Hillner BE, Siegel BA, Hanna L, Duan F, Shields AF, Coleman RE. "Impact of 18F-fluoride PET in patients with known prostate cancer: initial results from the National Oncologic PET Registry." Journal of Nuclear Medicine, vol. 55, no. 4, 2014, pp. 574-81. |
| Hillner BE, Siegel BA, Hanna L, Duan F, Shields AF, Quinn B, Coleman RE. "Impact of 18F-Fluoride PET on Intended Management of Patients with Cancers Other Than Prostate Cancer: Results from the National Oncologic PET Registry." Journal of Nuclear Medicine, vol. 55, no. 7, 2014, pp. 1054-1061. |
| Gareen IF, Duan F, Greco EM, Snyder BS, Boiselle PM, Park ER, Fryback D, Gatsonis C. "Impact of lung cancer screening results on participant health-related quality of life and state anxiety in the National Lung Screening Trial." Cancer, vol. 120, no. 21, 2014, pp. 3401-9. |
| Ohri, N., Duan, F., Machtay, M., Gorelick, J.J., Snyder, B.S., Alavi, A., Siegel, B., Johnson, D.W., Bradley, J.D., DeNittis, A.S., Werner-Wasik, M. "Metabolic Tumor Volume on FDG-PET Predicts Clinical Outcomes Following Chemoradiation Therapy for Locally Advanced Non-Small Cell Lung Cancer: A Secondary Analysis of ECOG-ACRIN 6668/RTOG 0235." International Journal of Radiation Oncology*Biology*Physics, vol. 90, no. 5, 2014, pp. S17. |
| Ohri, N., Duan, F., Machtay, M., Gorelick, J.J., Snyder, B.S., Alavi, A., Siegel, B., Johnson, D.W., Bradley, J.D., DeNittis, A.S., Werner-Wasik, M. "Metabolic Tumor Volume on FDG-PET Predicts Clinical Outcomes Following Chemoradiation Therapy for Locally-Advanced Non-small Cell Lung Cancer: A Secondary Analysis of ECOG-ACRIN 6668 / RTOG 0235." International Journal of Radiation Oncology*Biology*Physics, vol. 90, no. 1, 2014, pp. S144-S145. |
| Bazan, J.G., Duan, F., Snyder, B.S., Horng, D., Graves, E.E., Siegel, B.A., Machtay, M., Loo, B.W. "Metabolic Tumor Volume Predicts Overall Survival in Patients With Stage III Non-Small Cell Lung Cancer Treated on ACRIN 6668/RTOG 0235." International Journal of Radiation Oncology*Biology*Physics, vol. 90, no. 5, 2014, pp. S3-S4. |
| Machtay M, Siegel BA, Duan F, Snyder BS. "Reply to J.-S. Ryu et al and A.T. Berman et al." Journal of Clinical Oncology, vol. 32, no. 15, 2014, pp. 1632-3. |
| Markovina, S., Duan, F., Snyder, B.J., Siegel, B.A., Machtay, M., Bradley, J.D. "Residual Post-Treatment FDG Avidity in Regional Lymph Nodes Impacts Local-Regional Control in Patients Receiving Definitive Chemoradiation for Non-small Cell Lung Cancer: A Secondary Analysis of ACRIN 6668/RTOG 0235." International Journal of Radiation Oncology*Biology*Physics, vol. 90, no. 1, 2014, pp. S144. |
| Park ER, Gareen IF, Jain A, Ostroff JS, Duan F, Sicks JD, Rakowski W, Diefenbach M, Rigotti NA. "Examining whether lung screening changes risk perceptions: National Lung Screening Trial participants at 1-year follow-up." Cancer, vol. 119, no. 7, 2013, pp. 1306-13. |
| Machtay M, Duan F, Siegel BA, Snyder BS, Gorelick JJ, Reddin JS, Munden R, Johnson DW, Wilf LH, DeNittis A, Sherwin N, Cho KH, Kim SK, Videtic G, Neumann DR, Komaki R, Macapinlac H, Bradley JD, Alavi A. "Prediction of survival by [18F]fluorodeoxyglucose positron emission tomography in patients with locally advanced non-small-cell lung cancer undergoing definitive chemoradiation therapy: results of the ACRIN 6668/RTOG 0235 trial." Journal of Clinical Oncology, vol. 31, no. 30, 2013, pp. 3823-30. |
| National Lung Screening Trial Research Team, Church TR, Black WC, Aberle DR, Berg CD, Clingan KL, Duan F, Fagerstrom RM, Gareen IF, Gierada DS, Jones GC, Mahon I, Marcus PM, Sicks JD, Jain A, Baum S. "Results of initial low-dose computed tomographic screening for lung cancer." New England Journal of Medicine, vol. 368, no. 21, 2013, pp. 1980-91. |
| Aberle DR, DeMello S, Berg CD, Black WC, Brewer B, Church TR, Clingan KL, Duan F, Fagerstrom RM, Gareen IF, Gatsonis CA, Gierada DS, Jain A, Jones GC, Mahon I, Marcus PM, Rathmell JM, Sicks J, National Lung Screening Trial Research Team. "Results of the two incidence screenings in the National Lung Screening Trial." New England Journal of Medicine, vol. 369, no. 10, 2013, pp. 920-31. |
| Duan F, Smith LM, Gustafson DM, Zhang C, Dunlevy MJ, Gastier-Foster JM, Barr FG. "Genomic and clinical analysis of fusion gene amplification in rhabdomyosarcoma: a report from the Children's Oncology Group." Genes, chromosomes & cancer, vol. 51, no. 7, 2012, pp. 662-74. |
| Hillner BE, Siegel BA, Hanna L, Shields AF, Duan F, Gareen IF, Quinn B, Coleman RE. "Impact of 18F-FDG PET used after initial treatment of cancer: comparison of the National Oncologic PET Registry 2006 and 2009 cohorts." Journal of Nuclear Medicine, vol. 53, no. 5, 2012, pp. 831-7. |
| Liu L, Yannam GR, Nishikawa T, Yamamoto T, Basma H, Ito R, Nagaya M, Dutta-Moscato J, Stolz DB, Duan F, Kaestner KH, Vodovotz Y, Soto-Gutierrez A, Fox IJ. "The microenvironment in hepatocyte regeneration and function in rats with advanced cirrhosis." Hepatology, vol. 55, no. 5, 2012, pp. 1529-39. |
| Machtay, M., Duan, F., Snyder, B., Gorelick, J., DeNittis, A.S., Chiles, C., Mahon, I., Alavi, A., Siegel, B.A., Bradley, J.D. "Can Tumor FDG-PET Scan Uptake (SUV) Predict Local Control in Stage III NSCLC? Preliminary Results from ACRIN 6668/RTOG 0235." International Journal of Radiation Oncology*Biology*Physics, vol. 81, no. 2, 2011, pp. S134-S135. |
| Reichek JL, Duan F, Smith LM, Gustafson DM, O'Connor RS, Zhang C, Dunlevy MJ, Gastier-Foster JM, Barr FG. "Genomic and clinical analysis of amplification of the 13q31 chromosomal region in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group." Clin Cancer Res , vol. 17, no. 6, 2011, pp. 1463-73. |
| Hillner BE, Siegel BA, Shields AF, Duan F, Gareen IF, Hanna L, Coleman RE. "Impact of dedicated brain PET on intended patient management in participants of the national oncologic PET Registry." Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, vol. 13, no. 1, 2011, pp. 161-5. |
| National Lung Screening Trial Research Team, Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, Gareen IF, Gatsonis C, Marcus PM, Sicks JD. "Reduced lung-cancer mortality with low-dose computed tomographic screening." New England Journal of Medicine, vol. 365, no. 5, 2011, pp. 395-409. |
| Duan F, Pauley MA, Spindel ER, Zhang L, Norgren RB Jr. "Large scale analysis of positional effects of single-base mismatches on microarray gene expression data." BioData mining, vol. 3, no. 1, 2010, pp. 2. |
| Patz EF Jr, Caporaso NE, Dubinett SM, Massion PP, Hirsch FR, Minna JD, Gatsonis C, Duan F, Adams A, Apgar C, Medina RM, Aberle DR. "National Lung Cancer Screening Trial American College of Radiology Imaging Network Specimen Biorepository originating from the Contemporary Screening for the Detection of Lung Cancer Trial (NLST, ACRIN 6654): design, intent, and availability of specimens for validation of lung cancer biomarkers." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, vol. 5, no. 10, 2010, pp. 1502-6. |
| Coleman RE, Hillner BE, Shields AF, Duan F, Merlino DA, Hanna LG, Stine SH, Siegel BA. "PET and PET/CT reports: observations from the National Oncologic PET Registry." Journal of Nuclear Medicine, vol. 51, no. 1, 2010, pp. 158-63. |
| Wiederin J, Rozek W, Duan F, Ciborowski P. "Biomarkers of HIV-1 associated dementia: proteomic investigation of sera." Proteome science, vol. 7, 2009, pp. 8. |
| García, K., García, V., Pérez Laspiur, J., Duan, F., Meléndez, L.M. "Characterization of the Placental Macrophage Secretome: Implications for Antiviral Activity." Placenta, vol. 30, no. 2, 2009, pp. 149-155. |
| Barr FG, Duan F, Smith LM, Gustafson D, Pitts M, Hammond S, Gastier-Foster JM. "Genomic and clinical analyses of 2p24 and 12q13-q14 amplification in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group." Genes, chromosomes & cancer, vol. 48, no. 8, 2009, pp. 661-72. |
| Toro-Nieves, Dm, Rodriguez, Y, Plaud, M, Ciborowski, P, Duan, F, Laspiur, J Pérez, Wojna, V, Meléndez, LM. "Proteomic analyses of monocyte-derived macrophages infected with human immunodeficiency virus type 1 primary isolates from Hispanic women with and without cognitive impairment." J Neurovirol, vol. 15, no. 1, 2009, pp. 36-50. |
| Chaudhuri A, Duan F, Morsey B, Persidsky Y, Kanmogne GD. "HIV-1 activates proinflammatory and interferon-inducible genes in human brain microvascular endothelial cells: putative mechanisms of blood-brain barrier dysfunction." Journal of Cerebral Blood Flow & Metabolism, vol. 28, no. 4, 2008, pp. 697-711. |
| Buescher JL, Duan F, Sun J, Price RW, Ikezu T. "OTK18 Levels in Plasma and Cerebrospinal Fluid Correlate with Viral Load and CD8 T-cells in Normal and AIDS Patients." Journal of Neuroimmune Pharmacology, vol. 3, no. 4, 2008, pp. 230-235. |
| Garcia, Katia, Garcia, Vivian, Perez, Juliana, Duan, Fenghai, Melendez, Loyda. "Placental and Monocyte-derived Macrophages have Different Secretome." Antiviral Research, vol. 78, no. 2, 2008, pp. A39. |
| Luciano-Montalvo, C., Ciborowski, P., Duan, F., Gendelman, H.E., Meléndez, L.M. "Proteomic Analyses Associate Cystatin B with Restricted HIV-1 Replication in Placental Macrophages." Placenta, vol. 29, no. 12, 2008, pp. 1016-1023. |
| Berro, A.I., Sugiura, H., Liu, X., Duan, F., Kawasaki, S., Togo, S., Kamio, K., Wang, X.Q., Mao, L., Ahn, Y., Ertl, R.F., Casale, T.B., Rennard, S.I. "Airway Fibroblasts Isolated from Mouse Model of Allergic Asthma Display Distinct Cellular and Phenotypic Characteristics as Compared to Normal Fibroblasts." Journal of Allergy and Clinical Immunology, vol. 119, no. 1, 2007, pp. S301. |
| Laspiur JP, Anderson ER, Ciborowski P, Wojna V, Rozek W, Duan F, Mayo R, Rodríguez E, Plaud-Valentín M, Rodríguez-Orengo J, Gendelman HE, Meléndez LM. "CSF proteomic fingerprints for HIV-associated cognitive impairment." Journal of Neuroimmunology, vol. 192, no. 1-2, 2007, pp. 157-70. |
| Sugiura, Hisatoshi, Liu, Xiangde, Duan, Fenghai, Kawasaki, Shin, Togo, Shinsaku, Kamio, Koichiro, Wang, Xing Qi, Mao, Lijun, Ahn, Youngsoo, Ertl, Ronald F., Bargar, Tom W., Berro, Abdo, Casale, Thomas B., Rennard, Stephen I. "Cultured Lung Fibroblasts from Ovalbumin-Challenged “Asthmatic” Mice Differ Functionally from Normal." American Journal of Respiratory Cell and Molecular Biology, vol. 37, no. 4, 2007, pp. 424-430. |
| Duan F, Spindel ER, Li YH, Norgren RB Jr. "Intercenter reliability and validity of the rhesus macaque GeneChip." BMC genomics, vol. 8, 2007, pp. 61. |
| Liao, Jason J. Z., Duan, Fenghai. "Calibrating the concentration from a serial dilution process." J. Chemometrics, vol. 20, no. 6-7, 2006, pp. 294-301. |
| Duan F, Zhang H. "Correcting the loss of cell-cycle synchrony in clustering analysis of microarray data using weights." Bioinformatics, vol. 20, no. 11, 2004, pp. 1766-71. |
Dr. Duan's research interests include high-throughput data analysis, bioinformatics, diagnostic test and biomarker evaluation and radio(geno)mics.
Dr. Duan's research work can be summarized into two categories: methodological research and multidisciplinary research. His methodological research advances the statistical science in the areas of bioinformatics, machine learning, reliability assessment, diagnostic test and marker evaluations in biomedical research. His early multidisciplinary research focuses on the cancer signature’s discovery through the data analysis of various high-throughput experiments for genomics, proteomics, genome amplification studies. Recently, Dr. Duan mainly collaborates with investigators from ECOG-ACRIN to run the clinical trials guided by the advanced medical imaging, which advances the clinical science on oncology research, particularly lung cancer (LC) research. In addition, motivated by his collaborative research on various lung cancer studies, Dr. Duan is developing a research line to combine the imaging and molecular markers in the lung cancer’s risk prediction modeling (e.g., radiogenomics in lung cancers for high-dimensional markers). Currently, he is the lead statistician for a number of ECOG-ACRIN and DECAMP clinical trials, varying across different cancer types and imaging modailities. Aside from the ACRIN studies, Dr. Duan is the statistician for the National Oncologic PET Registry (NOPR), a nationwide prospective internet-based registry with the primary goal of assessing the effect of PET on referring physicians’ plans of intended patient management. Dr. Duan has publications on the journals of New England Journal of Medicine, Journal of Clinical Oncology, Radiology, Journal of Nuclear Medicine, Clinical Cancer Research, Bioinformatics, BMC Genomics, and so on.
ONGOING RESEARCH SUPPORT
(PI: Duan) 01/01/17-12/31/19
Janssen/Trustees of Boston University
Detection of Early Lung Cancer Among Military Personnel (DECAMP)
This research project involves supporting the establishment and operation of a Biostatistics Core for a proposed consortium that will develop and validate molecular biomarkers that can serve as tools for early detection of lung cancer. The Biostatistics Core based at Brown University will provide methodological expertise and leadership in the design, development and implementation of the DECAMP studies.
(PI: Duan) 01/01/17-12/31/19
DOD/Walter Reed National Military Medical Center
Genomics of Early Lung Cancer Among Military Personnel (GELCAMP)
The primary AIM is to identify airway genomic alterations in military personnel with early lung cancer that may be used as a biomarker for early diagnosis or screening. The secondary AIM is to identify genomic alterations in the airway or tumor that are prognostic in terms of predicting tumor aggressiveness among those with early stage lung cancer.
(PI: Duan/Gatsonis) 08/01/16-7/31/19
Blue Earth Diagnostics
Blue Earth Diagnostics Multi-Center Trial of FACBC
The Center for Statistical Sciences (CSS), Brown University will be responsible for providing methodological expertise in the design, development, and implementation of the study.
(Duan and Gareen- MPI) 01/01/17-12/31/17
World Molecular Imaging Society
NOPR NaF CMS Collaboration
The primary endpoint of this study is to conduct the confirmatory analyses of the NOPR data and administrative claims data for NOPR patients. Specifically, this study intends to examine the similarities and differences between physicians’ intended patient management as reported on case report forms for the registry and actual management inferred from their claims data. The BC is integrated closely with the investigators and Operations Centers (HQ) to manage and oversee the conduct of the study.
U01 CA196408 (PI Dubinett, Subcontract PI Duan) 09/16/15-08/31/18
UCLA/NCI
Integrated Molecular, Cellular and Imaging Characterization of Screen-Detected Lung Cancer
This subcontract provides support for establishing and operating a Biostatistics Core. This proposal will 1) identify molecular, cellular and imaging profiles that distinguish screen detected from non-screen detected lung cancers using the clinical, imaging and specimens data from the DECAMP studies and the UC, BU and Lahey Clinic screening programs, and 2) Identify molecular, cellular and imaging profiles that distinguish screen-detected lung cancers with indolent versus aggressive clinical courses from a previously collected screening cohort (NLST collected tumor tissues), and 3) Identify molecular, cellular and imaging profiles that distinguish screen-detected lung cancers with indolent versus aggressive clinical courses from a prospectively collected screening cohort.
U54 GM115677 (Schmid) 07/01/2016-04/30/21
NIGMS
RI-Center for Clinical and Translational Science
The Brown Institute for Translational Sciences, and a statewide consortium of collaborators, hospitals, universities, and government agencies will use the IDeA Clinical Translational Research Award to build infrastructure and support for clinical and translational research.
Role: Co-Investigator
U10 CA 180794 (PI: Gatsonis/Gray) 04/29/14-02/28/19
Dana Farber/NCI
ECOG-ACRIN Network Group Statistics and Data Management Center
This subcontract covers support for the operations of Brown office of the Statistics and Data Management Center (SDMC) of ECOG-ACRIN Cancer Research Group. The SDMC is organized and operated jointly by the Department of Biostatistics and Computational Biology at the Dana-Farber Cancer Institute (DFCI), the Department of Biostatistics at Brown University, the Frontier Science and Technology Research Foundation (FSTRF) and the American College of Radiology (ACR), under the direction of the Group Statisticians.
Role: Faculty Statistician
U01 CA190254 (PI Schnall CSS PI Gatsonis) 03/20/15-02/28/20
American College of Radiology/NCI
ECOG-ACRIN-Based QIN Resource for Advancing Quantitative Cancer imaging in Clinical Trials
This subcontract will provide support for CSS participation in the ECOG-ACRIN Quantitative Imaging Network (QIN) resource for advancing quantitative cancer imaging in clinical trials. CSS faculty and staff will provide methodologic expertise, leadership and support for the design of studies by QIN investigators using ECOG-ACRIN quantitative imaging and clinical data, the incorporation of QIN developed advanced image analysis methods and metrics into new ECOG-ACRIN trials, and the development and implementation of evaluations of image metrics.
Role: Faculty Statistician
(Gatsonis) 06/01/15-06/30/20
ACR
Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Study
The Center for Statistical Sciences (CSS), Brown University will be responsible for overseeing all data collection, review and analysis efforts associated with the IDEAS Study.
Role: Faculty Statistician
PENDING
(Gatsonis)
ACR/NCI 08/1/17-7/31/25
ECOG-ACRIN Tomosynthesis Mammographic Imaging Screening Trial (TMIST)
The responsibilities of the Center for Statistical Sciences with respect to this study are summarized below:
Role: Faculty Statistician
| Name | Title |
|---|---|
| Gareen, Ilana | Associate Professor of Epidemiology (Research) |
| Gatsonis, Constantine | Henry Ledyard Goddard University Professor of Statistical Sciences, Director of the Center for Statistical Sciences |
| Zhang, Zheng | Adjunct Assistant Professor of Biostatistics |
Professional Societies
American Statistical Association
International Biometric Society, Eastern North American Region
International Chinese Statistical Association
Editorial board
Journal of Molecular Diagnostics
Journal of Biometrics & Biostatistics
Scientific Reports
