Constantine Gatsonis, PhD, Henry Ledyard Goddard University Professor of Biostatistic was educated at Princeton and Cornell and joined the Brown faculty in 1995. He is the founding Director of the Center for Statistical Sciences and the founding Chair of the Department of Biostatistics. Dr. Gatsonis is a leading authority on the evaluation of diagnostic and screening tests, and has made major contributions to the development of methods for medical technology assessment and health services and outcomes research. He is a world leader in methods for applying and synthesizing evidence on diagnostic tests in medicine and is currently developing methods for Comparative Effectiveness Research in diagnosis and prediction and radiomics.
Dr Gatsonis was Network Statistician of the American College of Radiology Imaging Network (ACRIN) since the formation of the Network in 1999. The Center for Statistical Sciences at Brown operates the Biostatistics Center of ACRIN under his direction. With the recent formation of ECOG-ACRIN, Dr Gatsonis serves as a Group Statistician for the combined collaborative group, which conducts NCI-funded multi-center clinical studies across the spectrum of cancer care. He is the lead statistician for several current and past trials, including the Digital Mammography Imaging Screening Trial (DMIST), the National Lung Screening Trial (NLST), and the newly launched Tomosynthesis Mammography Imaging Trial (TMIST).
Dr Gatsonis has contributed extensively to statistical methods for the evaluation of diagnostic tests and biomarkers. He has published on methodology for ROC analysis for detection and prediction and on broader issues of study design in diagnostic test and imaging biomarker evaluation and validation. Dr Gatsonis has long-term involvement in the development of Bayesian statistical methods for problems in biomedical research. He developed and applied hierarchical regression models to the analysis variations in utilization, outcomes, and quality of health care, meta-analysis of diagnostic test accuracy studies, and the variability in diagnostic performance among radiologists and institutions.
Dr Gatsonis chaired the Committee on Applied and Theoretical Statistics of the National Academies and is a member of the Committee on National Statistics and the Committee on Reproducibility and Replicability in Science. Previously, he co-chaired the Committee on the Needs of the Forensic Sciences Communityand served on the Board of Mathematical Sciences and Applications and several IOM Committees. Since 2016 Dr Garsonis is a statistical consultant for the New England Journal of Medicine. He was the Founding Editor-in-Chief of Health Services and Outcomes Research Methods, and currently serves as Associate Editor of the Annals of Applied Statistics and Academic Radiology. . Dr. Gatsonis was elected fellow of the American Statistical Association and received a Long-Term Excellence Award from the Health Policy Statistics Section of the ASA.
| Dahabreh IJ, Gatsonis C. "A Flexible, Multifaceted Approach Is Needed in Health Technology Assessment of PET." Journal of Nuclear Medicine, vol. 55, no. 8, 2014, pp. 1225-1227. |
| Rahbar H, Hanna LG, Gatsonis C, Mahoney MC, Schnall MD, DeMartini WB, Lehman CD. "Contralateral Prophylactic Mastectomy in the American College of Radiology Imaging Network 6667 Trial: Effect of Breast MR Imaging Assessments and Patient Characteristics." Radiology, vol. 273, no. 1, 2014, pp. 53-60. |
| Gareen IF, Duan F, Greco EM, Snyder BS, Boiselle PM, Park ER, Fryback D, Gatsonis C. "Impact of lung cancer screening results on participant health-related quality of life and state anxiety in the National Lung Screening Trial." Cancer, vol. 120, no. 21, 2014, pp. 3401-9. |
| Patz EF Jr, Pinsky P, Gatsonis C, Sicks JD, Kramer BS, Tammemägi MC, Chiles C, Black WC, Aberle DR, NLST Overdiagnosis Manuscript Writing Team. "Overdiagnosis in low-dose computed tomography screening for lung cancer." JAMA Internal Medicine, vol. 174, no. 2, 2014, pp. 269-74. |
| Raunig DL, McShane LM, Pennello G, Gatsonis C, Carson PL, Voyvodic JT, Wahl RL, Kurland BF, Schwarz AJ, Gönen M, Zahlmann G, Kondratovich M, O'Donnell K, Petrick N, Cole PE, Garra B, Sullivan DC, QIBA Technical Performance Working Group. "Quantitative imaging biomarkers: A review of statistical methods for technical performance assessment." Statistical methods in medical research, 2014. |
| Li H, Gatsonis C. "Sample size estimation for time-dependent receiver operating characteristic." Statistics in Medicine, vol. 33, no. 6, 2014, pp. 958-70. |
| Lu B, Gatsonis C. "Efficiency of study designs in diagnostic randomized clinical trials." Statistics in Medicine, vol. 32, no. 9, 2013, pp. 1451-66. |
| Divgi CR, Uzzo RG, Gatsonis C, Bartz R, Treutner S, Yu JQ, Chen D, Carrasquillo JA, Larson S, Bevan P, Russo P. "Positron emission tomography/computed tomography identification of clear cell renal cell carcinoma: results from the REDECT trial." Journal of Clinical Oncology, vol. 31, no. 2, 2013, pp. 187-94. |
| Aberle DR, DeMello S, Berg CD, Black WC, Brewer B, Church TR, Clingan KL, Duan F, Fagerstrom RM, Gareen IF, Gatsonis CA, Gierada DS, Jain A, Jones GC, Mahon I, Marcus PM, Rathmell JM, Sicks J, National Lung Screening Trial Research Team. "Results of the two incidence screenings in the National Lung Screening Trial." New England Journal of Medicine, vol. 369, no. 10, 2013, pp. 920-31. |
| Van den Abbeele AD, Gatsonis C, de Vries DJ, Melenevsky Y, Szot-Barnes A, Yap JT, Godwin AK, Rink L, Huang M, Blevins M, Sicks J, Eisenberg B, Siegel BA. "ACRIN 6665/RTOG 0132 phase II trial of neoadjuvant imatinib mesylate for operable malignant gastrointestinal stromal tumor: monitoring with 18F-FDG PET and correlation with genotype and GLUT4 expression." Journal of Nuclear Medicine, vol. 53, no. 4, 2012, pp. 567-74. |
| Lowry KP, Lee JM, Kong CY, McMahon PM, Gilmore ME, Cott Chubiz JE, Pisano ED, Gatsonis C, Ryan PD, Ozanne EM, Gazelle GS. "Annual screening strategies in BRCA1 and BRCA2 gene mutation carriers: a comparative effectiveness analysis." Cancer, vol. 118, no. 8, 2012, pp. 2021-30. |
| Cole EB, Zhang Z, Marques HS, Nishikawa RM, Hendrick RE, Yaffe MJ, Padungchaichote W, Kuzmiak C, Chayakulkheeree J, Conant EF, Fajardo LL, Baum J, Gatsonis C, Pisano E. "Assessing the stand-alone sensitivity of computer-aided detection with cancer cases from the Digital Mammographic Imaging Screening Trial." American Journal of Roentgenology, vol. 199, no. 3, 2012, pp. W392-401. |
| Litt HI, Gatsonis C, Snyder B, Singh H, Miller CD, Entrikin DW, Leaming JM, Gavin LJ, Pacella CB, Hollander JE. "CT angiography for safe discharge of patients with possible acute coronary syndromes." New England Journal of Medicine, vol. 366, no. 15, 2012, pp. 1393-403. |
| Li, Hong, Gatsonis, Constantine. "Dynamic optimal strategy for monitoring disease recurrence." Science China Mathematics, vol. 55, no. 8, 2012, pp. 1565-1582. |
| DeMartini WB, Hanna L, Gatsonis C, Mahoney MC, Lehman CD. "Evaluation of tissue sampling methods used for MRI-detected contralateral breast lesions in the American College of Radiology Imaging Network 6667 trial." American Journal of Roentgenology, vol. 199, no. 3, 2012, pp. W386-91. |
| Hillman BJ, Frank RA, Rodriguez GM, Medical Imaging & Technology Alliance (MITA) Workshop Participants. "New pathways to medicare coverage for innovative PET radiopharmaceuticals: report of a Medical Imaging & Technology Alliance (MITA) workshop." Journal of the American College of Radiology : JACR, vol. 9, no. 2, 2012, pp. 108-14. |
| Hillman BJ, Frank RA, Rodriguez GM, Medical Imaging & Technology Alliance (MITA) Workshop participants. "New pathways to medicare coverage for innovative PET radiopharmaceuticals: report of a medical imaging & technology alliance (MITA) workshop." Journal of Nuclear Medicine, vol. 53, no. 2, 2012, pp. 336-42. |
| Shiu SY, Gatsonis C. "On ROC analysis with nonbinary reference standard." Biometrical journal. Biometrische Zeitschrift, vol. 54, no. 4, 2012, pp. 457-80. |
| Mahoney MC, Gatsonis C, Hanna L, DeMartini WB, Lehman C. "Positive predictive value of BI-RADS MR imaging." Radiology, vol. 264, no. 1, 2012, pp. 51-8. |
| Johnson CD, Herman BA, Chen MH, Toledano AY, Heiken JP, Dachman AH, Kuo MD, Menias CO, Siewert B, Cheema JI, Obregon R, Fidler JL, Zimmerman P, Horton KM, Coakley KJ, Iyer RB, Hara AK, Halvorsen RA Jr, Casola G, Yee J, Blevins M, Burgart LJ, Limburg PJ, Gatsonis CA. "The National CT Colonography Trial: assessment of accuracy in participants 65 years of age and older." Radiology, vol. 263, no. 2, 2012, pp. 401-8. |
| Buckler AJ, Bresolin L, Dunnick NR, Sullivan DC, Group. "A collaborative enterprise for multi-stakeholder participation in the advancement of quantitative imaging." Radiology, vol. 258, no. 3, 2011, pp. 906-14. |
| Stillman AE, Woodard PK, RESCUE Investigators. "Consequence of overuse of invasive coronary angiography." Arch Intern Med, vol. 171, no. 7, 2011, pp. 709; author reply 709-10. |
| Liu T, Gatsonis CA, Baylin A, Kubzansky LD, Loucks EB, Buka SL. "Maternal smoking during pregnancy and anger temperament among adult offspring." Journal of Psychiatric Research, vol. 45, no. 12, 2011, pp. 1648-54. |
| Buckler AJ, Bresolin L, Dunnick NR, Sullivan DC, Aerts HJ, Bendriem B, Bendtsen C, Boellaard R, Boone JM, Cole PE, Conklin JJ, Dorfman GS, Douglas PS, Eidsaunet W, Elsinger C, Frank RA, Gatsonis C, Giger ML, Gupta SN, Gustafson D, Hoekstra OS, Jackson EF, Karam L, Kelloff GJ, Kinahan PE, McLennan G, Miller CG, Mozley PD, Muller KE, Patt R, Raunig D, Rosen M, Rupani H, Schwartz LH, Siegel BA, Sorensen AG, Wahl RL, Waterton JC, Wolf W, Zahlmann G, Zimmerman B. "Quantitative imaging test approval and biomarker qualification: interrelated but distinct activities." Radiology, vol. 259, no. 3, 2011, pp. 875-84. |
| National Lung Screening Trial Research Team, Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, Gareen IF, Gatsonis C, Marcus PM, Sicks JD. "Reduced lung-cancer mortality with low-dose computed tomographic screening." New England Journal of Medicine, vol. 365, no. 5, 2011, pp. 395-409. |
| Sullivan DC, Gatsonis C. "Response to treatment series: part 1 and introduction, measuring tumor response--challenges in the era of molecular medicine." American Journal of Roentgenology, vol. 197, no. 1, 2011, pp. 15-7. |
| National Lung Screening Trial Research Team., Aberle DR, Berg CD, Black WC, Church TR, Fagerstrom RM, Galen B, Gareen IF, Gatsonis C, Goldin J, Gohagan JK, Hillman B, Jaffe C, Kramer BS, Lynch D, Marcus PM, Schnall M, Sullivan DC, Sullivan D, Zylak CJ. "The National Lung Screening Trial: overview and study design." Radiology, vol. 258, no. 1, 2011, pp. 243-53. |
| National Lung Screening Trial Research Team, Aberle DR, Adams AM, Berg CD, Clapp JD, Clingan KL, Gareen IF, Lynch DA, Marcus PM, Pinsky PF. "Baseline characteristics of participants in the randomized national lung screening trial." JNCI Journal of the National Cancer Institute, vol. 102, no. 23, 2010, pp. 1771-9. |
| Hendrick RE, Pisano ED, Averbukh A, Moran C, Berns EA, Yaffe MJ, Herman B, Acharyya S, Gatsonis C. "Comparison of acquisition parameters and breast dose in digital mammography and screen-film mammography in the American College of Radiology Imaging Network digital mammographic imaging screening trial." American Journal of Roentgenology, vol. 194, no. 2, 2010, pp. 362-9. |
| Weinstein SP, Hanna LG, Gatsonis C, Schnall MD, Rosen MA, Lehman CD. "Frequency of malignancy seen in probably benign lesions at contrast-enhanced breast MR imaging: findings from ACRIN 6667." Radiology, vol. 255, no. 3, 2010, pp. 731-7. |
| Patz EF Jr, Caporaso NE, Dubinett SM, Massion PP, Hirsch FR, Minna JD, Gatsonis C, Duan F, Adams A, Apgar C, Medina RM, Aberle DR. "National Lung Cancer Screening Trial American College of Radiology Imaging Network Specimen Biorepository originating from the Contemporary Screening for the Detection of Lung Cancer Trial (NLST, ACRIN 6654): design, intent, and availability of specimens for validation of lung cancer biomarkers." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, vol. 5, no. 10, 2010, pp. 1502-6. |
| Liu T, Gatsonis CA, Baylin A, Buka SL. "Prenatal exposure to cigarette smoke and benign breast disease." Epidemiology, vol. 21, no. 5, 2010, pp. 736-43. |
| Gatsonis C. "The promise and realities of comparative effectiveness research." Statistics in Medicine, vol. 29, no. 19, 2010, pp. 1977-81; discussion 1996-7. |
| Pisano ED, Acharyya S, Cole EB, Marques HS, Yaffe MJ, Blevins M, Conant EF, Hendrick RE, Baum JK, Fajardo LL, Jong RA, Koomen MA, Kuzmiak CM, Lee Y, Pavic D, Yoon SC, Padungchaichote W, Gatsonis C. "Cancer cases from ACRIN digital mammographic imaging screening trial: radiologist analysis with use of a logistic regression model." Radiology, vol. 252, no. 2, 2009, pp. 348-57. |
| Nishikawa RM, Acharyya S, Gatsonis C, Pisano ED, Cole EB, Marques HS, D'Orsi CJ, Farria DM, Kanal KM, Mahoney MC, Rebner M, Staiger MJ, Digital Mammography Image Screening Trial investigator group. "Comparison of soft-copy and hard-copy reading for full-field digital mammography." Radiology, vol. 251, no. 1, 2009, pp. 41-9. |
| Yu K, Sabelli A, DeKeukelaere L, Park R, Sindi S, Gatsonis CA, Salomon A. "Integrated platform for manual and high-throughput statistical validation of tandem mass spectra." PROTEOMICS, vol. 9, no. 11, 2009, pp. 3115-25. |
| Gatsonis CA. "Receiver operating characteristic analysis for the evaluation of diagnosis and prediction." Radiology, vol. 253, no. 3, 2009, pp. 593-6. |
| Sargent DJ, Rubinstein L, Schwartz L, Dancey JE, Gatsonis C, Dodd LE, Shankar LK. "Validation of novel imaging methodologies for use as cancer clinical trial end-points." European journal of cancer (Oxford, England : 1990), vol. 45, no. 2, 2009, pp. 290-9. |
| Hendrick RE, Cole EB, Pisano ED, Acharyya S, Marques H, Cohen MA, Jong RA, Mawdsley GE, Kanal KM, D'Orsi CJ, Rebner M, Gatsonis C. "Accuracy of soft-copy digital mammography versus that of screen-film mammography according to digital manufacturer: ACRIN DMIST retrospective multireader study." Radiology, vol. 247, no. 1, 2008, pp. 38-48. |
| Weissman JS, Schneider EC, Weingart SN, Epstein AM, David-Kasdan J, Feibelmann S, Annas CL, Ridley N, Kirle L, Gatsonis C. "Comparing patient-reported hospital adverse events with medical record review: do patients know something that hospitals do not?." Annals of Internal Medicine, vol. 149, no. 2, 2008, pp. 100-8. |
| Irwig, Les M., Bossuyt, Patrick M. M., Glasziou, Paul P., Gatsonis, Constantine, Lijmer, Jeroen G. "Designing Studies to Ensure that Estimates of Test Accuracy Will Travel." The Evidence Base of Clinical Diagnosis, 2008, pp. 96-117. |
| Pisano ED, Hendrick RE, Yaffe MJ, Baum JK, Acharyya S, Cormack JB, Hanna LA, Conant EF, Fajardo LL, Bassett LW, D'Orsi CJ, Jong RA, Rebner M, Tosteson AN, Gatsonis CA, DMIST Investigators Group. "Diagnostic accuracy of digital versus film mammography: exploratory analysis of selected population subgroups in DMIST." Radiology, vol. 246, no. 2, 2008, pp. 376-83. |
| Wang F, Gatsonis CA. "Hierarchical models for ROC curve summary measures: design and analysis of multi-reader, multi-modality studies of medical tests." Statistics in Medicine, vol. 27, no. 2, 2008, pp. 243-56. |
| Schneider EC, Rosenthal M, Gatsonis CG, Zheng J, Epstein AM. "Is the type of Medicare insurance associated with colorectal cancer screening prevalence and selection of screening strategy?." Medical Care, vol. 46, no. 9 Suppl 1, 2008, pp. S84-90. |
| Leeflang MM, Deeks JJ, Gatsonis C, Bossuyt PM, Cochrane Diagnostic Test Accuracy Working Group. "Systematic reviews of diagnostic test accuracy." Annals of Internal Medicine, vol. 149, no. 12, 2008, pp. 889-97. |
| Hillman BJ, Gatsonis C. "The American College Of Radiology Imaging Network--clinical trials of diagnostic imaging and image-guided treatment." Seminars in oncology, vol. 35, no. 5, 2008, pp. 460-9. |
| Shiu SY, Gatsonis C. "The predictive receiver operating characteristic curve for the joint assessment of the positive and negative predictive values." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, vol. 366, no. 1874, 2008, pp. 2313-33. |
| Hillman BJ, Gatsonis CA. "When is the right time to conduct a clinical trial of a diagnostic imaging technology?." Radiology, vol. 248, no. 1, 2008, pp. 12-5. |
| Zhou XH, Li SM, Gatsonis CA. "Wilcoxon-based group sequential designs for comparison of areas under two correlated ROC curves." Statistics in Medicine, vol. 27, no. 2, 2008, pp. 213-23. |
| Lehman CD, Isaacs C, Schnall MD, Pisano ED, Ascher SM, Weatherall PT, Bluemke DA, Bowen DJ, Marcom PK, Armstrong DK, Domchek SM, Tomlinson G, Skates SJ, Gatsonis C. "Cancer yield of mammography, MR, and US in high-risk women: prospective multi-institution breast cancer screening study." Radiology, vol. 244, no. 2, 2007, pp. 381-8. |
| Hricak H, Gatsonis C, Coakley FV, Snyder B, Reinhold C, Schwartz LH, Woodward PJ, Pannu HK, Amendola M, Mitchell DG. "Early invasive cervical cancer: CT and MR imaging in preoperative evaluation - ACRIN/GOG comparative study of diagnostic performance and interobserver variability." Radiology, vol. 245, no. 2, 2007, pp. 491-8. |
| Lehman CD, Gatsonis C, Kuhl CK, Hendrick RE, Pisano ED, Hanna L, Peacock S, Smazal SF, Maki DD, Julian TB, DePeri ER, Bluemke DA, Schnall MD, ACRIN Trial 6667 Investigators Group. "MRI evaluation of the contralateral breast in women with recently diagnosed breast cancer." New England Journal of Medicine, vol. 356, no. 13, 2007, pp. 1295-303. |
| Pisano ED, Hendrick RE, Yaffe M, Conant EF, Gatsonis C. "Should breast imaging practices convert to digital mammography? A response from members of the DMIST Executive Committee." Radiology, vol. 245, no. 1, 2007, pp. 12-3. |
| Schnall MD, Blume J, Bluemke DA, DeAngelis GA, DeBruhl N, Harms S, Heywang-Köbrunner SH, Hylton N, Kuhl CK, Pisano ED, Causer P, Schnitt SJ, Thickman D, Stelling CB, Weatherall PT, Lehman C, Gatsonis CA. "Diagnostic architectural and dynamic features at breast MR imaging: multicenter study." Radiology, vol. 238, no. 1, 2006, pp. 42-53. |
| Gatsonis C, Paliwal P. "Meta-analysis of diagnostic and screening test accuracy evaluations: methodologic primer." American Journal of Roentgenology, vol. 187, no. 2, 2006, pp. 271-81. |
| Lehman CD, Blume JD, Thickman D, Bluemke DA, Pisano E, Kuhl C, Julian TB, Hylton N, Weatherall P, O'loughlin M, Schnitt SJ, Gatsonis C, Schnall MD. "Added cancer yield of MRI in screening the contralateral breast of women recently diagnosed with breast cancer: results from the International Breast Magnetic Resonance Consortium (IBMC) trial." Journal of surgical oncology, vol. 92, no. 1, 2005, pp. 9-15; discussion 15-6. |
| Pisano ED, Gatsonis CA, Yaffe MJ, Hendrick RE, Tosteson AN, Fryback DG, Bassett LW, Baum JK, Conant EF, Jong RA, Rebner M, D'Orsi CJ. "American College of Radiology Imaging Network digital mammographic imaging screening trial: objectives and methodology." Radiology, vol. 236, no. 2, 2005, pp. 404-12. |
| Pisano ED, Gatsonis C, Hendrick E, Yaffe M, Baum JK, Acharyya S, Conant EF, Fajardo LL, Bassett L, D'Orsi C, Jong R, Rebner M, Digital Mammographic Imaging Screening Trial (DMIST) Investigators Group. "Diagnostic performance of digital versus film mammography for breast-cancer screening." New England Journal of Medicine, vol. 353, no. 17, 2005, pp. 1773-83. |
| Weissman JS, Annas CL, Epstein AM, Schneider EC, Clarridge B, Kirle L, Gatsonis C, Feibelmann S, Ridley N. "Error reporting and disclosure systems: views from hospital leaders." JAMA, vol. 293, no. 11, 2005, pp. 1359-66. |
| Aberle DR, Chiles C, Gatsonis C, Hillman BJ, Johnson CD, McClennan BL, Mitchell DG, Pisano ED, Schnall MD, Sorensen AG, American College of Radiology Imaging Network. "Imaging and cancer: research strategy of the American College of Radiology Imaging Network." Radiology, vol. 235, no. 3, 2005, pp. 741-51. |
| Schnall MD, Blume J, Bluemke DA, Deangelis GA, Debruhl N, Harms S, Heywang-Köbrunner SH, Hylton N, Kuhl CK, Pisano ED, Causer P, Schnitt SJ, Smazal SF, Stelling CB, Lehman C, Weatherall PT, Gatsonis CA. "MRI detection of distinct incidental cancer in women with primary breast cancer studied in IBMC 6883." Journal of surgical oncology, vol. 92, no. 1, 2005, pp. 32-8. |
| Hricak H, Gatsonis C, Chi DS, Amendola MA, Brandt K, Schwartz LH, Koelliker S, Siegelman ES, Brown JJ, McGhee RB Jr, Iyer R, Vitellas KM, Snyder B, Long HJ 3rd, Fiorica JV, Mitchell DG, American College of Radiology Imaging Network 6651, Gynecologic Oncology Group 183. "Role of imaging in pretreatment evaluation of early invasive cervical cancer: results of the intergroup study American College of Radiology Imaging Network 6651-Gynecologic Oncology Group 183." Journal of Clinical Oncology, vol. 23, no. 36, 2005, pp. 9329-37. |
| Lehman CD, Blume JD, Weatherall P, Thickman D, Hylton N, Warner E, Pisano E, Schnitt SJ, Gatsonis C, Schnall M, DeAngelis GA, Stomper P, Rosen EL, O'Loughlin M, Harms S, Bluemke DA, International Breast MRI Consortium Working Group. "Screening women at high risk for breast cancer with mammography and magnetic resonance imaging." Cancer, vol. 103, no. 9, 2005, pp. 1898-905. |
| Amendola MA, Hricak H, Mitchell DG, Snyder B, Chi DS, Long HJ 3rd, Fiorica JV, Gatsonis C. "Utilization of diagnostic studies in the pretreatment evaluation of invasive cervical cancer in the United States: results of intergroup protocol ACRIN 6651/GOG 183." Journal of Clinical Oncology, vol. 23, no. 30, 2005, pp. 7454-9. |
| Bluemke DA, Gatsonis CA, Chen MH, DeAngelis GA, DeBruhl N, Harms S, Heywang-Köbrunner SH, Hylton N, Kuhl CK, Lehman C, Pisano ED, Causer P, Schnitt SJ, Smazal SF, Stelling CB, Weatherall PT, Schnall MD. "Magnetic resonance imaging of the breast prior to biopsy." JAMA, vol. 292, no. 22, 2004, pp. 2735-42. |
| Wahl RL, Siegel BA, Coleman RE, Gatsonis CG, PET Study Group. "Prospective multicenter study of axillary nodal staging by positron emission tomography in breast cancer: a report of the staging breast cancer with PET Study Group." Journal of Clinical Oncology, vol. 22, no. 2, 2004, pp. 277-85. |
| Fajardo LL, Pisano ED, Caudry DJ, Gatsonis CA, Berg WA, Connolly J, Schnitt S, Page DL, McNeil BJ, Radiologist Investigators of the Radiologic Diagnostic Oncology Group V. "Stereotactic and sonographic large-core biopsy of nonpalpable breast lesions: results of the Radiologic Diagnostic Oncology Group V study." Academic Radiology, vol. 11, no. 3, 2004, pp. 293-308. |
| Hillman BJ, Gatsonis C, Schnall MD. "The ACR imaging network: a retrospective on 5 years of conducting multicenter trials in radiology and plans for the future." Journal of the American College of Radiology : JACR, vol. 1, no. 5, 2004, pp. 346-50. |
| Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, Lijmer JG, Moher D, Rennie D, de Vet HC, STARD Group. "Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative." Family practice, vol. 21, no. 1, 2004, pp. 4-10. |
| Leape LL, Weissman JS, Schneider EC, Piana RN, Gatsonis C, Epstein AM. "Adherence to practice guidelines: the role of specialty society guidelines." American Heart Journal, vol. 145, no. 1, 2003, pp. 19-26. |
| Gatsonis C. "Do we need a checklist for reporting the results of diagnostic test evaluations? The STARD proposal." Academic Radiology, vol. 10, no. 6, 2003, pp. 599-600. |
| Dukic V, Gatsonis C. "Meta-analysis of diagnostic test accuracy assessment studies with varying number of thresholds." Biometrics, vol. 59, no. 4, 2003, pp. 936-46. |
| Gareen IF, Gatsonis C. "Primer on multiple regression models for diagnostic imaging research." Radiology, vol. 229, no. 2, 2003, pp. 305-10. |
| Epstein AM, Weissman JS, Schneider EC, Gatsonis C, Leape LL, Piana RN. "Race and gender disparities in rates of cardiac revascularization: do they reflect appropriate use of procedures or problems in quality of care?." Medical Care, vol. 41, no. 11, 2003, pp. 1240-55. |
| Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, Moher D, Rennie D, de Vet HC, Lijmer JG, Standards for Reporting of Diagnostic Accuracy. "The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration." Annals of Internal Medicine, vol. 138, no. 1, 2003, pp. W1-12. |
| Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, Lijmer JG, Moher D, Rennie D, de Vet HC, STARD Group. "Toward complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative." Academic Radiology, vol. 10, no. 6, 2003, pp. 664-9. |
| Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, Lijmer JG, Moher D, Rennie D, de Vet HC, Standards for Reporting of Diagnostic Accuracy. "Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative." Annals of Internal Medicine, vol. 138, no. 1, 2003, pp. 40-4. |
| Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, Lijmer JG, Moher D, Rennie D, de Vet HC, Standards for Reporting of Diagnostic Accuracy. "Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative." Clinical Radiology, vol. 58, no. 8, 2003, pp. 575-80. |
| Irwig L, Bossuyt P, Glasziou P, Gatsonis C, Lijmer J. "Designing studies to ensure that estimates of test accuracy are transferable." BMJ, vol. 324, no. 7338, 2002, pp. 669-71. |
| Wright TC, Holinka CF, Ferenczy A, Gatsonis CA, Mutter GL, Nicosia S, Richart RM. "Estradiol-induced hyperplasia in endometrial biopsies from women on hormone replacement therapy." The American Journal of Surgical Pathology, vol. 26, no. 10, 2002, pp. 1269-75. |
| Rutter CM, Gatsonis CA. "A hierarchical regression approach to meta-analysis of diagnostic test accuracy evaluations." Statistics in Medicine, vol. 20, no. 19, 2001, pp. 2865-84. |
| Pisano ED, Fajardo LL, Caudry DJ, Sneige N, Frable WJ, Berg WA, Tocino I, Schnitt SJ, Connolly JL, Gatsonis CA, McNeil BJ. "Fine-needle aspiration biopsy of nonpalpable breast lesions in a multicenter clinical trial: results from the radiologic diagnostic oncology group V." Radiology, vol. 219, no. 3, 2001, pp. 785-92. |
| Schneider EC, Leape LL, Weissman JS, Piana RN, Gatsonis C, Epstein AM. "Racial differences in cardiac revascularization rates: does "overuse" explain higher rates among white patients?." Annals of Internal Medicine, vol. 135, no. 5, 2001, pp. 328-37. |
| Ishwaran, Hemant, Gatsonis, Constantine A. "A general class of hierarchical ordinal regression models with applications to correlated roc analysis." Canadian Journal of Statistics, vol. 28, no. 4, 2000, pp. 731-750. |
| Gatsonis C. "Design of evaluations of imaging technologies: development of a paradigm." Academic Radiology, vol. 7, no. 9, 2000, pp. 681-3. |
| Gambassi G, Lapane KL, Sgadari A, Carbonin P, Gatsonis C, Lipsitz LA, Mor V, Bernabei R. "Effects of angiotensin-converting enzyme inhibitors and digoxin on health outcomes of very old patients with heart failure. SAGE Study Group. Systematic Assessment of Geriatric drug use via Epidemiology." Arch Intern Med, vol. 160, no. 1, 2000, pp. 53-60. |
| Jacob RG, Thayer JF, Manuck SB, Muldoon MF, Tamres LK, Williams DM, Ding Y, Gatsonis C. "Ambulatory blood pressure responses and the circumplex model of mood: a 4-day study." Psychosomatic Medicine, vol. 61, no. 3, 1999, pp. 319-33. |
| Bernabei R, Gambassi G, Lapane K, Sgadari A, Landi F, Gatsonis C, Lipsitz L, Mor V. "Characteristics of the SAGE database: a new resource for research on outcomes in long-term care. SAGE (Systematic Assessment of Geriatric drug use via Epidemiology) Study Group." The Journals of Gerontology: Series A, vol. 54, no. 1, 1999, pp. M25-33. |
| Toledano AY, Gatsonis C. "Generalized estimating equations for ordinal categorical data: arbitrary patterns of missing responses and missingness in a key covariate." Biometrics, vol. 55, no. 2, 1999, pp. 488-96. |
| Daniels, Michael J., Gatsonis, Constantine. "Hierarchical Generalized Linear Models in the Analysis of Variations in Health Care Utilization." Journal of the American Statistical Association, vol. 94, no. 445, 1999, pp. 29-42. |
| Weissman JS, Haas JS, Fowler FJ Jr, Gatsonis C, Massagli MP, Seage GR 3rd, Cleary P. "The stability of preferences for life-sustaining care among persons with AIDS in the Boston Health Study." Medical decision making : an international journal of the Society for Medical Decision Making, vol. 19, no. 1, 1999, pp. 16-26. |
| Bernabei R, Gambassi G, Lapane K, Landi F, Gatsonis C, Dunlop R, Lipsitz L, Steel K, Mor V. "Management of pain in elderly patients with cancer. SAGE Study Group. Systematic Assessment of Geriatric Drug Use via Epidemiology." JAMA, vol. 279, no. 23, 1998, pp. 1877-82. |
| Pisano ED, Fajardo LL, Tsimikas J, Sneige N, Frable WJ, Gatsonis CA, Evans WP, Tocino I, McNeil BJ. "Rate of insufficient samples for fine-needle aspiration for nonpalpable breast lesions in a multicenter clinical trial: The Radiologic Diagnostic Oncology Group 5 Study. The RDOG5 investigators." Cancer, vol. 82, no. 4, 1998, pp. 679-88. |
| Panicek DM, Gatsonis C, Rosenthal DI, Seeger LL, Huvos AG, Moore SG, Caudry DJ, Palmer WE, McNeil BJ. "CT and MR imaging in the local staging of primary malignant musculoskeletal neoplasms: Report of the Radiology Diagnostic Oncology Group." Radiology, vol. 202, no. 1, 1997, pp. 237-46. |
| Kovacs M, Obrosky DS, Gatsonis C, Richards C. "First-episode major depressive and dysthymic disorder in childhood: clinical and sociodemographic factors in recovery." Journal of the American Academy of Child & Adolescent Psychiatry, vol. 36, no. 6, 1997, pp. 777-84. |
| Daniels MJ, Gatsonis C. "Hierarchical polytomous regression models with applications to health services research." Statistics in Medicine, vol. 16, no. 20, 1997, pp. 2311-25. |
| Normand, Sharon-Lise T., Glickman, Mark E., Gatsonis, Constantine A. "Statistical Methods for Profiling Providers of Medical Care: Issues and Applications." Journal of the American Statistical Association, vol. 92, no. 439, 1997, pp. 803-814. |
| Seage GR 3rd, Gatsonis C, Weissman JS, Haas JS, Cleary PD, Fowler FJ, Massagli MP, Stone VE, Craven DE, Makadon H, Goldberg J, Coltin K, Levin KS, Epstein AM. "The Boston AIDS Survival Score (BASS): a multidimensional AIDS severity instrument." American Journal of Public Health, vol. 87, no. 4, 1997, pp. 567-73. |
| Zhou XH, Gatsonis CA. "A simple method for comparing correlated ROC curves using incomplete data." Statistics in Medicine, vol. 15, no. 15, 1996, pp. 1687-93. |
| Zerhouni EA, Rutter C, Hamilton SR, Balfe DM, Megibow AJ, Francis IR, Moss AA, Heiken JP, Tempany CM, Aisen AM, Weinreb JC, Gatsonis C, McNeil BJ. "CT and MR imaging in the staging of colorectal carcinoma: report of the Radiology Diagnostic Oncology Group II." Radiology, vol. 200, no. 2, 1996, pp. 443-51. |
| Toledano AY, Gatsonis C. "Ordinal regression methodology for ROC curves derived from correlated data." Statistics in Medicine, vol. 15, no. 16, 1996, pp. 1807-26. |
| Weissman JS, Cleary PD, Seage GR 3rd, Gatsonis C, Haas JS, Chasan-Taber S, Epstein AM. "The influence of health-related quality of life and social characteristics on hospital use by patients with AIDS in the Boston Health Study." Medical Care, vol. 34, no. 10, 1996, pp. 1037-56. |
| Colin C, Toselli A, Delahaye F, Ecochard R, Rabilloud M, Excoffier S, Milon H, Gatsonis C, Mabriez JC, Matillon Y. "[Management of myocardial infarction in the Rhone-Alps area. Are there many variations in practice?]." Archives des maladies du coeur et des vaisseaux, vol. 88, no. 3, 1995, pp. 307-13. |
| Epstein AM, Seage G 3rd, Weissman JS, Cleary PD, Fowler FJ, Gatsonis C, Massagli MP, Stone VE, Coltin K, Craven DE. "Costs of medical care and out-of-pocket expenditures for persons with AIDS in the Boston Health Study." INQUIRY: The Journal of Health Care Organization, Provision, and Financing, vol. 32, no. 2, 1995, pp. 211-21. |
| Gatsonis CA. "Random-effects models for diagnostic accuracy data." Academic Radiology, vol. 2 Suppl 1, 1995, pp. S14-21; discussion S57-67, S61-4 pa. |
| Toledano A, Gatsonis CA. "Regression analysis of correlated receiver operating characteristic data." Academic Radiology, vol. 2 Suppl 1, 1995, pp. S30-6; discussion S61-4, S70-1 pass. |
| Rutter CM, Gatsonis CA. "Regression methods for meta-analysis of diagnostic test data." Academic Radiology, vol. 2 Suppl 1, 1995, pp. S48-56; discussion S65-7, S70-1 pas. |
| Gatsonis CA, Epstein AM, Newhouse JP, Normand SL, McNeil BJ. "Variations in the utilization of coronary angiography for elderly patients with an acute myocardial infarction. An analysis using hierarchical logistic regression." Medical Care, vol. 33, no. 6, 1995, pp. 625-42. |
| Kovacs M, Gatsonis C, Pollock M, Parrone PL. "A controlled prospective study of DSM-III adjustment disorder in childhood. Short-term prognosis and long-term predictive validity." Archives of General Psychiatry , vol. 51, no. 7, 1994, pp. 535-41. |
| Weissman JS, Makadon HJ, Seage GR 3rd, Massagli MP, Gatsonis CA, Craven DE, Stone VE, Bennett IA, Epstein AM. "Changes in insurance status and access to care for persons with AIDS in the Boston Health Study." American Journal of Public Health, vol. 84, no. 12, 1994, pp. 1997-2000. |
| Kovacs M, Akiskal HS, Gatsonis C, Parrone PL. "Childhood-onset dysthymic disorder. Clinical features and prospective naturalistic outcome." Archives of General Psychiatry , vol. 51, no. 5, 1994, pp. 365-74. |
| Irwig L, Tosteson AN, Gatsonis C, Lau J, Colditz G, Chalmers TC, Mosteller F. "Guidelines for meta-analyses evaluating diagnostic tests." Annals of Internal Medicine, vol. 120, no. 8, 1994, pp. 667-76. |
| Ellis JH, Tempany C, Sarin MS, Gatsonis C, Rifkin MD, McNeil BJ. "MR imaging and sonography of early prostatic cancer: pathologic and imaging features that influence identification and diagnosis." American Journal of Roentgenology, vol. 162, no. 4, 1994, pp. 865-72. |
| Wahl RL, Hawkins RA, Larson SM, Hendee WR, Coleman RE, Holden RW, Frick MP, Gatsonis C, Brown GS, Shtern F. "Proceedings of a National Cancer Institute workshop: PET in oncology--a clinical research agenda." Radiology, vol. 193, no. 3, 1994, pp. 604-6. |
| Kovacs M, Gatsonis C. "Secular trends in age at onset of major depressive disorder in a clinical sample of children." Journal of Psychiatric Research, vol. 28, no. 3, 1994, pp. 319-29. |
| Haas JS, Weissman JS, Cleary PD, Goldberg J, Gatsonis C, Seage GR 3rd, Fowler FJ Jr, Massagli MP, Makadon HJ, Epstein AM. "Discussion of preferences for life-sustaining care by persons with AIDS. Predictors of failure in patient-physician communication." Arch Intern Med, vol. 153, no. 10, 1993, pp. 1241-8. |
| Gatsonis C, Normand SL, Liu C, Morris C. "Geographic variation of procedure utilization. A hierarchical model approach." Medical Care, vol. 31, no. 5 Suppl, 1993, pp. YS54-9. |
| Cleary PD, Fowler FJ Jr, Weissman J, Massagli MP, Wilson I, Seage GR 3rd, Gatsonis C, Epstein A. "Health-related quality of life in persons with acquired immune deficiency syndrome." Medical Care, vol. 31, no. 7, 1993, pp. 569-80. |
| Webb WR, Sarin M, Zerhouni EA, Heelan RT, Glazer GM, Gatsonis C. "Interobserver variability in CT and MR staging of lung cancer." Journal of Computer Assisted Tomography, vol. 17, no. 6, 1993, pp. 841-6. |
| Ayanian JZ, Udvarhelyi IS, Gatsonis CA, Pashos CL, Epstein AM. "Racial differences in the use of revascularization procedures after coronary angiography." JAMA, vol. 269, no. 20, 1993, pp. 2642-6. |
| Kovacs M, Goldston D, Gatsonis C. "Suicidal behaviors and childhood-onset depressive disorders: a longitudinal investigation." Journal of the American Academy of Child & Adolescent Psychiatry, vol. 32, no. 1, 1993, pp. 8-20. |
| Sidtis JJ, Gatsonis C, Price RW, Singer EJ, Collier AC, Richman DD, Hirsch MS, Schaerf FW, Fischl MA, Kieburtz K. "Zidovudine treatment of the AIDS dementia complex: results of a placebo-controlled trial. AIDS Clinical Trials Group." Annals of neurology, vol. 33, no. 4, 1993, pp. 343-9. |
| Udvarhelyi IS, Gatsonis C, Epstein AM, Pashos CL, Newhouse JP, McNeil BJ. "Acute myocardial infarction in the Medicare population. Process of care and clinical outcomes." JAMA, vol. 268, no. 18, 1992, pp. 2530-6. |
| Gatsonis C, Greenhouse JB. "Bayesian methods for phase I clinical trials." Statistics in Medicine, vol. 11, no. 10, 1992, pp. 1377-89. |
| McNeil BJ, Pedersen SH, Gatsonis C. "Current issues in profiling quality of care." INQUIRY: The Journal of Health Care Organization, Provision, and Financing, vol. 29, no. 3, 1992, pp. 298-307. |
| Filderman AE, Silvestri GA, Gatsonis C, Luthringer DJ, Honig J, Flynn SD. "Prognostic significance of tumor proliferative fraction and DNA content in stage I non-small cell lung cancer." The American review of respiratory disease, vol. 146, no. 3, 1992, pp. 707-10. |
| Weissman JS, Gatsonis C, Epstein AM. "Rates of avoidable hospitalization by insurance status in Massachusetts and Maryland." JAMA, vol. 268, no. 17, 1992, pp. 2388-94. |
| Jacob RG, Shapiro AP, O'Hara P, Portser S, Kruger A, Gatsonis C, Ding Y. "Relaxation therapy for hypertension: setting-specific effects." Psychosomatic Medicine, vol. 54, no. 1, 1992, pp. 87-101. |
| Webb WR, Gatsonis C, Zerhouni EA, Heelan RT, Glazer GM, Francis IR, McNeil BJ. "CT and MR imaging in staging non-small cell bronchogenic carcinoma: report of the Radiologic Diagnostic Oncology Group." Radiology, vol. 178, no. 3, 1991, pp. 705-13. |
| Gatsonis C, McNeil BJ. "Collaborative evaluations of diagnostic tests: experience of the Radiology Diagnostic Oncology Group." Radiology, vol. 175, no. 2, 1990, pp. 571-5. |
| Rifkin MD, Zerhouni EA, Gatsonis CA, Quint LE, Paushter DM, Epstein JI, Hamper U, Walsh PC, McNeil BJ. "Comparison of magnetic resonance imaging and ultrasonography in staging early prostate cancer. Results of a multi-institutional cooperative trial." New England Journal of Medicine, vol. 323, no. 10, 1990, pp. 621-6. |
| Byar DP, Schoenfeld DA, Green SB, Amato DA, Davis R, De Gruttola V, Finkelstein DM, Gatsonis C, Gelber RD, Lagakos S. "Design considerations for AIDS trials." New England Journal of Medicine, vol. 323, no. 19, 1990, pp. 1343-8. |
| Needleman HL, Gatsonis CA. "Low-level lead exposure and the IQ of children. A meta-analysis of modern studies." JAMA, vol. 263, no. 5, 1990, pp. 673-8. |
| Gatsonis C. "The long debate on the sixth guaiac test: time to move on to new grounds." Journal of health economics, vol. 9, no. 4, 1990, pp. 495-7. |
| Kovacs M, Gatsonis C, Paulauskas SL, Richards C. "Depressive disorders in childhood. IV. A longitudinal study of comorbidity with and risk for anxiety disorders." Archives of General Psychiatry , vol. 46, no. 9, 1989, pp. 776-82. |
| Gatsonis C, Sampson AR. "Multiple correlation: exact power and sample size calculations." Psychological Bulletin, vol. 106, no. 3, 1989, pp. 516-24. |
| Bucephala, John P., Gatsonis, Constantine A. "Bayesian Inference for Ratios of Coefficients in a Linear Model." Biometrics, vol. 44, no. 1, 1988, pp. 87. |
| Kovacs M, Paulauskas S, Gatsonis C, Richards C. "Depressive disorders in childhood. III. A longitudinal study of comorbidity with and risk for conduct disorders." Journal of affective disorders, vol. 15, no. 3, 1988, pp. 205-17. |
| Gatsonis, Constantine, MacGibbon, Brenda, Strawderman, William. "On the estimation of a restricted normal mean." Statistics & Probability Letters, vol. 6, no. 1, 1987, pp. 21-30. |
| Gatsonis, Constantine, Hsieh, H. K., Korwar, Ramesh. "Simple nonparametric tests for a known standard survival based on censored data." Communications in Statistics - Theory and Methods, vol. 14, no. 9, 1985, pp. 2137-2162. |
| Gatsonis, Constantine A. "Deriving Posterior Distributions for a Location Parameter: A Decision Theoretic Approach." The Annals of Statistics, vol. 12, no. 3, 1984, pp. 958-970. |
| Cohen, Arthur, Gatsonis, Constantine, Marden, John I. "Hypothesis Testing for Marginal Probabilities in a 2 × 2 × 2 Contingency Table with Conditional Independence." Journal of the American Statistical Association, vol. 78, no. 384, 1983, pp. 920-929. |
Statistical theory and methods
Interdisciplinary research
Most of my current interdisciplinary research is conducted through ACRIN and ECOG-ACRIN.
Selected currently funded projects
U10 CA180794 (Dual PIs Gray, Gatsonis) 03/01/14-02/25/19
NCI
ECOG-ACRIN Network Group Statistics and Data Management Center
UG1 CA 189828-01-BRWN1 (Subcontract PI Gatsonis) 08/01/14-07/31/19
NCI/ECOG-ACRIN
ECOG-ACRIN NCORP Research Base - CT
UG1 CA 189828-01-BRWN2 (Subcontract PI Gatsonis) 08/01/14-07/31/19
NCI/ECOG-ACRIN
ECOG-ACRIN NCORP Research Base - CCDR
5UG1 CA189828-03-BRWN4 (Subcontract PI Gatsonis) 08/01/16-07/31/25
EAMRF/NCI
ECOG-ACRIN Tomosynthesis Mammographic Imaging Screening Trial (TMIST) Transition
U01 CA190254 (PI Schnall, CSS Sub PI Gatsonis) 03/20/15-02/29/20
ACR/NCI
ECOG-ACRIN-Based QIN Resource for Advancing Quantitative Cancer imaging in Clinical Trials
ACR ( PI Gatsonis) 06/01/15 – 06/30/20
Biostatistics Center for Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Study
| Year | Degree | Institution |
|---|---|---|
| 1981 | PhD | Cornell University |
| 1978 | MS | Cornell University |
Phi Beta Kappa (1976)
National Research Service Award, National Institute of Mental Health (1986-1988)
Fellow, Association for Health Services Research (1997)
Fellow, American Statistical Association (1998)
Spinoza Visiting Professor, Academic Medical Center, University of Amsterdam, Netherlands (June 2003)
Long-Term Excellence Award, Health Policy Statistics Section, Amer. Stat. Assoc.(2015)
| Name | Title |
|---|---|
| Duan, Fenghai | Associate Professor of Biostatistics |
| Gareen, Ilana | Associate Professor of Epidemiology (Research) |
| Liu, Tao | Director of Biostatistics, Associate Professor of Biostatistics |
| Schmid, Christopher | Professor of Biostatistics |
| Steingrimsson, Jon | Assistant Professor of Biostatistics |
Recent Professional Activities (since 2007)
a. National Committees
2007 - 2009 Co-Chair, Committee on Identifying the Needs of the Forensic Sciences Community, National Academies
2008 –2010 Member, Committee to Study Engineering Aviation Security Environments: False Positives from Explosive Detection System, National Academies
2009 Member, Committee on Comparative Effectiveness Research Prioritization, Institute of Medicine
2011 Member, Committee on Scientific Standards for Studies on Reduced Risk Tobacco Products, Institute of Medicine
2001 - 2014 Member, Board on Mathematical Sciences and their Applications, National Academies
2012 - present Member, Committee on National Statistics, National Academies
2012 - 2017 Chair, Committee on Applied and Theoretical Statistics, National Academies
2013 - 2017 Member, Committee to Evaluate the Department of Veterans Affairs Mental Health Services, Institute of Medicine
2017 - present Member, Committee on Reproducibility and Replicability in Science, National Academies
b. Review and advisory panels
2007 Member, Development and Discovery P01 Special Emphasis Panel, NCI
2007-2008 Member, Institutional Clinical Translational Science Award (CTSA) Center Special Emphasis Panel, NIH
2007, 2010, 2011 Member, In Vivo Cellular and Molecular Imaging (ICMIC) Centers, Special Emphasis Panel, NCI
2009 Chair, Outside Review Committee of CISNET, NCI
2010 Chair, Accelerating Adoption of CER Results, Special Emphasis Panel, NIH
2011 Member, Technical Evaluation Panel, Cancer Prevention Agent Development Program: Early Phase Clinical Trials,
NCI 2011 – 2013 Chair, DSMB for Back Pain Outcomes using Longitudinal Data (BOLD) Lumbar Epidural Steroid Injections for Spinal Stenosis (LESS) trial.
2011 – Present Member, DSMB for Randomized Trial of Behavioral Economic Interventions to Reduce CVD Risk
2012,-2014 Member, Special Emphasis Review Panel, P01 Applications, NCI
c. Professional leadership and service
1997 - 2012 Co-convenor, Diagnostic and Screening Test Methods Working Group, Cochrane Collaboration.
2000- present Member, Steering Committee, STARD (Standards for Reporting of Diagnostic Accuracy Project
2005 – 2011 Founding Co-Director. Radiology Society of North America Clinical Trials Methodology Workshop.
2008 – present Member, Quantitative Imaging Biomarkers Alliance (QIBA), Radiology Society of North America (RSNA)
2008 - 2014 Member, Research Development Committee, RSNA.
2010 April Organizing Committee, RSNA/NIBIB Workshop on Comparative Effectiveness Research for diagnostic imaging.
2010 - present Member, Advisory Board, International Conference on Health Policy Statistics
c. Editorial positions
1998-2014 Founding Editor in Chief: Health Services and Outcomes Research Methodology
Associate Editor:
2003-2013 Clinical Trials
2005- 2010 Bayesian Analysis
2008 - present Annals of Applied Statistics
Editorial Boards:
2008 - 2016 Diagnostic Test Accuracy Reviews, Cochrane Collaboration
1996- present Academic Radiology
2011 - present Handbook for Health Services Research
2016 - present
| PHP 2570 - Health Data Science Case Studies |
| PHP 2580 - Statistical Inference II |
| PHP 2601 - Linear Models |
