Christopher H. Schmid, PhD is Professor of Biostatistics and founding member of the Center for Evidence Synthesis in Health in the Brown School of Public Health. He is Fellow of the American Statistical Association (ASA), elected member of the Society for Research Synthesis Methodology, Founding Editor of the journal Research Synthesis Methods, statistical editor for the American Journal of Kidney Diseases and former Chair of the Section on Health Policy Statistics at ASA. He directs the Biostatistics, Epidemiology and Research Design (BERD), Core of Advance-RI Clinical and Translational Research and the Evidence Synthesis Academy, an AHRQ-funded training program in evidence synthesis focusing on comparative effectiveness and patient-centered research directed at mid-career professionals and users of healthcare evidence.
His research focuses on methods and applications for meta-analysis, particularly Bayesian methods and software, on predictive models derived from combining data from different sources and on clinical trials, particularly N-of-1 trials, single person multiple crossover studies. He has published extensively on meta-regression and multivariate methods, including network meta-analysis and combining N-of-1 studies.
Dr. Schmid also has coauthored a large number of applications in collaboration with medical and public health scientists. He has published in all the leading general medical journals and in many top subspecialty journals as well.
Dr. Schmid helped develop Institute of Medicine national standards for systematic reviews. Before moving to Brown, Dr. Schmid was on the faculty of Tufts University School of Medicine from 1992-2012. He served as Director of the Biostatistics Research Center at Tufts Medical Center and as Associate Director of the Clinical and Translational Science program. He directed the Brown Biostatistics Masters Program from 2012-2016. Dr. Schmid holds a PhD in Statistics from Harvard University (1991) and a BA in Mathematics from Haverford College (1983). He consults extensively with government, academia and industry and has served on many data safety monitoring and grant review committees including most recently the AHRQ Health Care Research Training Study Section, the FDA Drug Safety and Risk Management Advisory Committee and the Scientific Advisory Committee of the Cochrane Collaboration.
Advance CTR
Center for Evidence Synthesis in Health
Department of Biostatistics
| Wang L, Rouse B, Marks-Anglin A, Duan R, Shi Q, Quach K, Chen Y, Cameron C, Schmid CH, Li T. "Rapid network meta-analysis using data from Food and Drug Administration approval packages is feasible but with limitations." American Journal of Kidney Diseases, vol. 114, 2019, pp. 84-94. |
| Schmid CH. "Contribution to the discussion of "When should meta-analysis avoid making hidden normality assumptions?." Biometrical journal. Biometrische Zeitschrift, vol. 60, no. 6, 2018, pp. 1087-1088. |
| Schmid CH. "Discussion of "quantifying publication bias in meta-analysis" by Lin et al." Biometrics, vol. 74, no. 3, 2018, pp. 797-799. |
| Kravitz RL, Schmid CH, Marois M, Wilsey B, Ward D, Hays RD, Duan N, Wang Y, MacDonald S, Jerant A, Servadio JL, Haddad D, Sim I. "Effect of Mobile Device-Supported Single-Patient Multi-crossover Trials on Treatment of Chronic Musculoskeletal Pain: A Randomized Clinical Trial." JAMA Internal Medicine, vol. 178, no. 10, 2018, pp. 1368-1377. |
| Wang, Chenchen, Schmid, Christopher H, Fielding, Roger A, Harvey, William F, Reid, Kieran F, Price, Lori Lyn, Driban, Jeffrey B, Kalish, Robert, Rones, Ramel, McAlindon, Timothy. "Effect of tai chi versus aerobic exercise for fibromyalgia: comparative effectiveness randomized controlled trial." BMJ, vol. 360, 2018, pp. k851. |
| Jap J, Saldanha IJ, Smith BT, Lau J, Schmid CH, Li T, Data Abstraction Assistant Investigators. "Features and functioning of Data Abstraction Assistant, a software application for data abstraction during systematic reviews." Research Synthesis Methods, 2018. |
| Chen Y, Liu Y, Chu H, Ting Lee ML, Schmid CH. "A simple and robust method for multivariate meta-analysis of diagnostic test accuracy." Statistics in Medicine, vol. 36, no. 1, 2017, pp. 105-121. |
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Dahabreh I, Kent D, Trikalinos T and Schmid CH.
"Heterogeneity of Treatment Effects." Methods in Comparative Effectiveness Research, edited by SC Morton and C Gatsonis, New York, Chapman & Hall, 2017, pp. 227-271.
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| Wallace, Byron C., Lajeunesse, Marc J., Dietz, George, Dahabreh, Issa J., Trikalinos, Thomas A., Schmid, Christopher H., Gurevitch, Jessica. "OpenMEE : Intuitive, open-source software for meta-analysis in ecology and evolutionary biology." Methods in Ecology and Evolution, vol. 8, no. 8, 2017, pp. 941-947. |
| Schmid CH. "Outcome Reporting Bias: A Pervasive Problem in Published Meta-analyses." American Journal of Kidney Diseases, vol. 69, no. 2, 2017, pp. 172-174. |
| Porcino AJ, Punja S, Chan AW, Kravitz R, Orkin A, Ravaud P, Schmid CH, Vohra S. "Protocol for a systematic review of N-of-1 trial protocol guidelines and protocol reporting guidelines." Systematic reviews, vol. 6, no. 1, 2017, pp. 132. |
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Lau J, Morton SC, Trikalinos TA and Schmid CH.
"Systematic Reviews with Study-Level and Individual Patient-Level Data." Methods in Comparative Effectiveness Research, edited by SC Morton and C Gatsonis, New York, Chapman & Hall, 2017, pp. 301-339.
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| Dahabreh, Issa J., Trikalinos, Thomas A., Lau, Joseph, Schmid, Christopher H. "Univariate and bivariate likelihood-based meta-analysis methods performed comparably when marginal sensitivity and specificity were the targets of inference." Journal of Clinical Epidemiology, vol. 83, 2017, pp. 8-17. |
| Rothstein H, Schmid C, Shrier I. "2016 Bulletin." Research Synthesis Methods, vol. 7, no. 1, 2016, pp. 5. |
| Schmid, Christopher H. "An interview with Constantine Gatsonis." Health Services and Outcomes Research Methodology, vol. 16, no. 4, 2016, pp. 187-212. |
| Wang C, Schmid CH, Iversen MD, Harvey WF, Fielding RA, Driban JB, Price LL, Wong JB, Reid KF, Rones R, McAlindon T. "Comparative Effectiveness of Tai Chi Versus Physical Therapy for Knee Osteoarthritis: A Randomized Trial." Annals of Internal Medicine, vol. 165, no. 2, 2016, pp. 77-86. |
| Inker LA, Mondal H, Greene T, Masaschi T, Locatelli F, Schena FP, Katafuchi R, Appel GB, Maes BD, Li PK, Praga M, Del Vecchio L, Andrulli S, Manno C, Gutierrez E, Mercer A, Carroll KJ, Schmid CH, Levey AS. "Early Change in Urine Protein as a Surrogate End Point in Studies of IgA Nephropathy: An Individual-Patient Meta-analysis." American Journal of Kidney Diseases, vol. 68, no. 3, 2016, pp. 392-401. |
| Saldanha IJ, Schmid CH, Lau J, Dickersin K, Berlin JA, Jap J, Smith BT, Carini S, Chan W, De Bruijn B, Wallace BC, Hutfless SM, Sim I, Murad MH, Walsh SA, Whamond EJ, Li T. "Evaluating Data Abstraction Assistant, a novel software application for data abstraction during systematic reviews: protocol for a randomized controlled trial." Systematic reviews, vol. 5, no. 1, 2016, pp. 196. |
| Levine AC, Glavis-Bloom J, Modi P, Nasrin S, Atika B, Rege S, Robertson S, Schmid CH, Alam NH. "External validation of the DHAKA score and comparison with the current IMCI algorithm for the assessment of dehydration in children with diarrhoea: a prospective cohort study." The Lancet. Global health, vol. 4, no. 10, 2016, pp. e744-51. |
| Schmid CH. "Heterogeneity: multiplicative, additive or both?." Research Synthesis Methods, 2016. |
| Schmid, Christopher H. "Increased mortality for white middle-aged Americans not fully explained by causes suggested." Proceedings of the National Academy of Sciences, vol. 113, no. 7, 2016, pp. E814-E814. |
| Norris SL, Zhang X, Avenell A, Gregg E, Brown T, Schmid CH, Lau J. "Long-term non-pharmacological weight loss interventions for adults with type 2 diabetes mellitus." Sao Paulo medical journal = Revista paulista de medicina, vol. 134, no. 2, 2016, pp. 184. |
| Punja S, Nikles CJ, Senior H, Mitchell G, Schmid CH, Heussler H, Witmans M, Vohra S. "Melatonin in Youth: N-of-1 trials in a stimulant-treated ADHD Population (MYNAP): study protocol for a randomized controlled trial." Trials, vol. 17, 2016, pp. 375. |
| Punja S, Xu D, Schmid CH, Hartling L, Urichuk L, Nikles CJ, Vohra S. "N-of-1 trials can be aggregated to generate group mean treatment effects: a systematic review and meta-analysis." American Journal of Kidney Diseases, vol. 76, 2016, pp. 65-75. |
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Schmid, CH.
"Review of Introduction to Scientific Programming and Simulation Using R (2nd ed) by O. Jones, R. Maillardet and A. Robinson." Journal of the American Statistical Association, vol. 111, 2016, pp. 443-444.
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| Whiting P, Savović J, Higgins JP, Caldwell DM, Reeves BC, Shea B, Davies P, Kleijnen J, Churchill R, ROBIS group. "ROBIS: A new tool to assess risk of bias in systematic reviews was developed." American Journal of Kidney Diseases, vol. 69, 2016, pp. 225-34. |
| Tate RL, Perdices M, Rosenkoetter U, Shadish W, Vohra S, Barlow DH, Horner R, Kazdin A, Kratochwill T, McDonald S, Sampson M, Shamseer L, Togher L, Albin R, Backman C, Douglas J, Evans JJ, Gast D, Manolov R, Mitchell G, Nickels L, Nikles J, Ownsworth T, Rose M, Schmid CH, Wilson B. "The Single-Case Reporting guideline In BEhavioural interventions (SCRIBE) 2016 statement." Journal of school psychology, vol. 56, 2016, pp. 133-42. |
| Tate RL, Perdices M, Rosenkoetter U, Shadish W, Vohra S, Barlow DH, Horner R, Kazdin A, Kratochwill T, McDonald S, Sampson M, Shamseer L, Togher L, Albin R, Backman C, Douglas J, Evans JJ, Gast D, Manolov R, Mitchell G, Nickels L, Nikles J, Ownsworth T, Rose M, Schmid CH, Wilson B. "The Single-Case Reporting Guideline In BEhavioural Interventions (SCRIBE) 2016 Statement." Physical Therapy, vol. 96, no. 7, 2016, pp. e1-e10. |
| Tate RL, Perdices M, Rosenkoetter U, Shadish W, Vohra S, Barlow DH, Horner R, Kazdin A, Kratochwill T, McDonald S, Sampson M, Shamseer L, Togher L, Albin R, Backman C, Douglas J, Evans JJ, Gast D, Manolov R, Mitchell G, Nickels L, Nikles J, Ownsworth T, Rose M, Schmid CH, Wilson B. "The Single-Case Reporting Guideline In BEhavioural Interventions (SCRIBE) 2016 Statement." American Journal of Kidney Diseases, vol. 73, 2016, pp. 142-52. |
| Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, McDonald, Skye, Togher, Leanne, Shadish, William, Horner, Robert, Kratochwill, Thomas, Barlow, David H., Kazdin, Alan, Sampson, Margaret, Shamseer, Larissa, Vohra, Sunita. "The Single-Case Reporting Guideline In BEhavioural Interventions (SCRIBE) 2016: Explanation and elaboration." Archives of Scientific Psychology, vol. 4, no. 1, 2016, pp. 10-31. |
| Punja S, Schmid CH, Hartling L, Urichuk L, Nikles CJ, Vohra S. "To meta-analyze or not to meta-analyze? A combined meta-analysis of N-of-1 trial data with RCT data on amphetamines and methylphenidate for pediatric ADHD." American Journal of Kidney Diseases, vol. 76, 2016, pp. 76-81. |
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Jin M, Li H, Schmid CH and Wallace BC.
"Using Electronic Medical Records and Physician Data to Improve Information Retrieval for Evidence-Based Care." 2016, pp. 61-64.
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| Wang, Chenchen, McAlindon, Timothy, Fielding, Roger A, Harvey, William F, Driban, Jeffrey B, Price, Lori Lyn, Kalish, Robert, Schmid, Anna, Scott, Tammy M, Schmid, Christopher H. "A novel comparative effectiveness study of Tai Chi versus aerobic exercise for fibromyalgia: study protocol for a randomized controlled trial." Trials, vol. 16, no. 1, 2015. |
| Bannuru, Raveendhara R., Schmid, Christopher H., Kent, David M., Vaysbrot, Elizaveta E., Wong, John B., McAlindon, Timothy E. "Comparative Effectiveness of Pharmacologic Interventions for Knee Osteoarthritis." Annals of Internal Medicine, vol. 162, no. 1, 2015, pp. 46. |
| Bannuru RR, Schmid CH, Kent DM, Vaysbrot EE, Wong JB, McAlindon TE. "Comparative effectiveness of pharmacologic interventions for knee osteoarthritis: a systematic review and network meta-analysis." Annals of Internal Medicine, vol. 162, no. 1, 2015, pp. 46-54. |
| Vohra, S., Shamseer, L., Sampson, M., Bukutu, C., Schmid, C. H., Tate, R., Nikles, J., Zucker, D. R., Kravitz, R., Guyatt, G., Altman, D. G., Moher, D. "CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement." BMJ, vol. 350, no. may14 17, 2015, pp. h1738-h1738. |
| Vohra S, Shamseer L, Sampson M, Bukutu C, Schmid CH, Tate R, Nikles J, Zucker DR, Kravitz R, Guyatt G, Altman DG, Moher D, CENT Group. "CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement." BMJ, vol. 350, 2015, pp. h1738. |
| Vohra S, Shamseer L, Sampson M, Bukutu C, Schmid CH, Tate R, Nikles J, Zucker DR, Kravitz R, Guyatt G, Altman DG, Moher D, CENT Group. "CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement." American Journal of Kidney Diseases, vol. 76, 2015, pp. 9-17. |
| Shamseer, L., Sampson, M., Bukutu, C., Schmid, C. H., Nikles, J., Tate, R., Johnston, B. C., Zucker, D., Shadish, W. R., Kravitz, R., Guyatt, G., Altman, D. G., Moher, D., Vohra, S. "CONSORT extension for reporting N-of-1 trials (CENT) 2015: Explanation and elaboration." BMJ, vol. 350, no. may14 15, 2015, pp. h1793-h1793. |
| Shamseer L, Sampson M, Bukutu C, Schmid CH, Nikles J, Tate R, Johnston BC, Zucker D, Shadish WR, Kravitz R, Guyatt G, Altman DG, Moher D, Vohra S, CENT group. "CONSORT extension for reporting N-of-1 trials (CENT) 2015: explanation and elaboration." American Journal of Kidney Diseases, vol. 76, 2015, pp. 18-46. |
| Shamseer L, Sampson M, Bukutu C, Schmid CH, Nikles J, Tate R, Johnston BC, Zucker D, Shadish WR, Kravitz R, Guyatt G, Altman DG, Moher D, Vohra S, CENT Group. "CONSORT extension for reporting N-of-1 trials (CENT) 2015: Explanation and elaboration." BMJ, vol. 350, 2015, pp. h1793. |
| Bannuru RR, McAlindon TE, Sullivan MC, Wong JB, Kent DM, Schmid CH. "Effectiveness and Implications of Alternative Placebo Treatments: A Systematic Review and Network Meta-analysis of Osteoarthritis Trials." Annals of Internal Medicine, vol. 163, no. 5, 2015, pp. 365-72. |
| Levine AC, Glavis-Bloom J, Modi P, Nasrin S, Rege S, Chu C, Schmid CH, Alam NH. "Empirically Derived Dehydration Scoring and Decision Tree Models for Children With Diarrhea: Assessment and Internal Validation in a Prospective Cohort Study in Dhaka, Bangladesh." Global health, science and practice, vol. 3, no. 3, 2015, pp. 405-18. |
| Bannuru, R.R., Wong, J.B., Kent, D.M., Schmid, C.H., McAlindon, T.E. "Intra-articular corticosteroids may be a cost-effective strategy for short-term management of knee osteoarthritis." Osteoarthritis and Cartilage, vol. 23, 2015, pp. A392-A394. |
| Stewart GB, Schmid CH. "Lessons from meta-analysis in ecology and evolution: the need for trans-disciplinary evidence synthesis methodologies." Research Synthesis Methods, vol. 6, no. 2, 2015, pp. 109-110. |
| Miligkos, Michael, Bannuru, Raveendhara R., Alkofide, Hadeel, Kher, Sucharita R., Schmid, Christopher H., Balk, Ethan M. "Leukotriene-Receptor Antagonists Versus Placebo in the Treatment of Asthma in Adults and Adolescents." Annals of Internal Medicine, vol. 163, no. 10, 2015, pp. 756. |
| Wagner M, Earley AK, Webster AC, Schmid CH, Balk EM, Uhlig K. "Mycophenolic acid versus azathioprine as primary immunosuppression for kidney transplant recipients." The Cochrane database of systematic reviews, no. 12, 2015, pp. CD007746. |
| Stewart LA, Clarke M, Rovers M, Riley RD, Simmonds M, Stewart G, Tierney JF, PRISMA-IPD Development Group. "Preferred Reporting Items for Systematic Review and Meta-Analyses of individual participant data: the PRISMA-IPD Statement." JAMA, vol. 313, no. 16, 2015, pp. 1657-65. |
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Mengersen K, McGree JM and Schmid CH.
"Statistical Analysis of N-of-1 Trials." The Essential Guide to N-of-1 Trials in Health, edited by J Nikles and G Mitchell, New York, Springer, 2015, pp. 135-153.
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Mengersen K, McGree JM and Schmid CH.
"Systematic Review and Meta-analysis Using N-of-1 Trials." The Essential Guide to N-of-1 Trials in Health, edited by J Nikles and G Mitchell, New York, Springer, 2015, pp. 211-232.
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| Barr C, Marois M, Sim I, Schmid CH, Wilsey B, Ward D, Duan N, Hays RD, Selsky J, Servadio J, Schwartz M, Dsouza C, Dhammi N, Holt Z, Baquero V, MacDonald S, Jerant A, Sprinkle R, Kravitz RL. "The PREEMPT study - evaluating smartphone-assisted n-of-1 trials in patients with chronic pain: study protocol for a randomized controlled trial." Trials, vol. 16, 2015, pp. 67. |
| Hutton B, Salanti G, Caldwell DM, Chaimani A, Schmid CH, Cameron C, Ioannidis JP, Straus S, Thorlund K, Jansen JP, Mulrow C, Catalá-López F, Gøtzsche PC, Dickersin K, Boutron I, Altman DG, Moher D. "The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations." Annals of Internal Medicine, vol. 162, no. 11, 2015, pp. 777-84. |
| Halladay CW, Trikalinos TA, Schmid IT, Schmid CH, Dahabreh IJ. "Using data sources beyond PubMed has a modest impact on the results of systematic reviews of therapeutic interventions." American Journal of Kidney Diseases, vol. 68, no. 9, 2015, pp. 1076-84. |
| Trikalinos TA, Hoaglin DC, Schmid CH. "An empirical comparison of univariate and multivariate meta-analyses for categorical outcomes." Statistics in Medicine, vol. 33, no. 9, 2014, pp. 1441-59. |
| Wang, Chenchen, Iversen, Maura D, McAlindon, Timothy, Harvey, William F, Wong, John B, Fielding, Roger A, Driban, Jeffrey B, Price, Lori, Rones, Ramel, Gamache, Tressa, Schmid, Christopher H. "Assessing the comparative effectiveness of Tai Chi versus physical therapy for knee osteoarthritis: design and rationale for a randomized trial." BMC Complementary and Alternative Medicine, vol. 14, no. 1, 2014, pp. 333. |
| Nikolakopoulou A, Chaimani A, Veroniki AA, Vasiliadis HS, Schmid CH, Salanti G. "Characteristics of networks of interventions: a description of a database of 186 published networks." PLoS ONE, vol. 9, no. 1, 2014, pp. e86754. |
| Kravitz RL, Duan N, eds, and the DEcIDE Methods Center N-of-1 Guidance Panel (Duan N, Eslick I, Gabler NB, Kaplan HC, Kravitz RL, Larson EB, Pace WD, Schmid CH, Sim I, Vohra S). Design and Implementation of N-of-1 Trials: A User’s Guide. Agency for Healthcare Research and Quality, 2014. |
| Bannuru, R.R., Schmid, C.H., Sullivan, M.C., Kent, D.M., Wong, J.B., McAlindon, T.E. "Differential response of placebo treatments in osteoarthritis trials: a systematic review and network meta-analysis." Osteoarthritis and Cartilage, vol. 22, 2014, pp. S24-S25. |
| Jessani S, Levey AS, Bux R, Inker LA, Islam M, Chaturvedi N, Mariat C, Schmid CH, Jafar TH. "Estimation of GFR in South Asians: a study from the general population in Pakistan." American Journal of Kidney Diseases, vol. 63, no. 1, 2014, pp. 49-58. |
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Wallace BC, Schmid CH, Lau J and Trikalinos TA.
"Evidence-Based Medicine and Meta-Analysis: Modernizing Evidence Synthesis." Clinical Decision Support: The Road to Broad Adoption, 2nd edition, edited by RA Greenes, New York, Academic Press, 2014, pp. 339-361.
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| Inker LA, Lambers Heerspink HJ, Mondal H, Schmid CH, Tighiouart H, Noubary F, Coresh J, Greene T, Levey AS. "GFR decline as an alternative end point to kidney failure in clinical trials: a meta-analysis of treatment effects from 37 randomized trials." American Journal of Kidney Diseases, vol. 64, no. 6, 2014, pp. 848-59. |
| Trikalinos, Thomas A., Hoaglin, David C., Small, Kevin M., Terrin, Norma, Schmid, Christopher H. "Methods for the joint meta-analysis of multiple tests." Research Synthesis Methods, vol. 5, no. 4, 2014, pp. 294-312. |
| Hutton B, Salanti G, Chaimani A, Caldwell DM, Schmid C, Thorlund K, Mills E, Catalá-López F, Turner L, Altman DG, Moher D. "The quality of reporting methods and results in network meta-analyses: an overview of reviews and suggestions for improvement." PLoS ONE, vol. 9, no. 3, 2014, pp. e92508. |
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Schmid CH and Mengersen K.
"Bayesian meta-analyses." Handbook of Meta-Analysis in Ecology and Evolution, edited by J Koricheva, J Gurevitch and K Mengersen, Princeton, NJ, Princeton University Press, 2013, pp. 145-173.
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| Schmid, Christopher H., Trikalinos, Thomas A., Olkin, Ingram. "Bayesian network meta-analysis for unordered categorical outcomes with incomplete data." Research Synthesis Methods, vol. 5, no. 2, 2013, pp. 162-185. |
| Chaimani A, Vasiliadis HS, Pandis N, Schmid CH, Welton NJ, Salanti G. "Effects of study precision and risk of bias in networks of interventions: a network meta-epidemiological study." International journal of epidemiology, vol. 42, no. 4, 2013, pp. 1120-31. |
| Trikalinos TA, Hoaglin DC, Schmid CH. Empirical and Simulation-Based Comparison of Univariate and Multivariate Meta-Analysis for Binary Outcomes. 2013. |
| Yu, Winifred W., Schmid, Christopher H., Lichtenstein, Alice H., Lau, Joseph, Trikalinos, Thomas A. "Empirical evaluation of meta-analytic approaches for nutrient and health outcome dose-response data." Research Synthesis Methods, 2013, pp. n/a-n/a. |
| Trikalinos TA, Hoaglin DC, Small KM, Schmid CH. Evaluating Practices and Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test Accuracy: Methods for the Joint Meta-Analysis of Multiple Tests. 2013. |
| Dahabreh, I. J., Schmid, C. H., Lau, J., Varvarigou, V., Murray, S., Trikalinos, T. A. "Genotype misclassification in genetic association studies of the rs1042522 TP53 (Arg72Pro) polymorphism: a systematic review of studies of breast, lung, colorectal, ovarian, and endometrial cancer." American Journal of Epidemiology, vol. 177, no. 12, 2013, pp. 1317-25. |
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Mengersen K and Schmid CH.
"Maximum likelihood approaches to meta-analysis." Handbook of Meta-Analysis in Ecology and Evolution, edited by J Koricheva, J Gurevitch and K Mengersen, Princeton, NJ, Princeton University Press, 2013, pp. 125-144.
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Mengersen K, Gurevitch J and Schmid CH.
"Meta-analysis of primary data." Handbook of Meta-Analysis in Ecology and Evolution, edited by J Koricheva, J Gurevitch and K Mengersen, Princeton, NJ, Princeton University Press, 2013, pp. 300-312.
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| Wallace BC, Dahabreh IJ, Schmid CH, Lau J, Trikalinos TA. "Modernizing the systematic review process to inform comparative effectiveness: tools and methods." Journal of comparative effectiveness research, vol. 2, no. 3, 2013, pp. 273-82. |
| Beidleman BA, Tighiouart H, Schmid CH, Fulco CS, Muza SR. "Predictive models of acute mountain sickness after rapid ascent to various altitudes." Medicine & Science in Sports & Exercise, vol. 45, no. 4, 2013, pp. 792-800. |
| Trikalinos TA, Trow P and Schmid CH. "Simulation-based Comparison of Methods for Meta-Analysis of Proportions and Rates." AHRQ Methods Research Report. AHRQ Publication No. 13-EHC066-EF, 2013. |
| Duan N, Kravitz RL, Schmid CH. "Single-patient (n-of-1) trials: a pragmatic clinical decision methodology for patient-centered comparative effectiveness research." American Journal of Kidney Diseases, vol. 66, no. 8 Suppl, 2013, pp. S21-8. |
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Schmid CH, Stewart G, Rothstein H and Gurevitch J.
"Software for meta-analysis." Handbook of Meta-Analysis in Ecology and Evolution, edited by J Koricheva, J Gurevitch and K Mengersen, Princeton, NJ, Princeton University Press, 2013, pp. 174-191.
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Mengersen K, Schmid CH, Jennions MD and Gurevitch J.
"Statistical models and approaches to inference for meta-analysis." Handbook of Meta-Analysis in Ecology and Evolution, edited by J Koricheva, J Gurevitch and K Mengersen, Princeton, NJ, Princeton University Press, 2013, pp. 89-107.
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Mengersen K, Jennions MD and Schmid CH.
"Statistical models for the meta-analysis of non-independent data." Handbook of Meta-Analysis in Ecology and Evolution, edited by J Koricheva, J Gurevitch and K Mengersen, Princeton, NJ, Princeton University Press, 2013, pp. 255-283.
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| Dahabreh IJ, Chung M, Kitsios GD, Terasawa T, Raman G, Tatsioni A, Tobar A, Lau J, Trikalinos TA, Schmid CH. "Survey of the methods and reporting practices in published meta-analyses of test performance: 1987 to 2009." Research Synthesis Methods, vol. 4, no. 3, 2013, pp. 242-55. |
| Schmid A, McAlindon T, Schmid CH and Wang C. "The Influence of Tai Chi Exercise on Proprioception in Patients with Knee Osteoarthritis: Results from a Pilot Randomized Controlled Trial." International Journal of Integrative Medicine, vol. 1, 2013, pp. 37. |
| Trikalinos TA, Dahabreh IJ, Wallace BC, Schmid CH and Lau J. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses. 2013. |
| Padala S, Tighiouart H, Inker LA, Contreras G, Beck GJ, Lewis J, Steffes M, Rodby RA, Schmid CH, Levey AS. "Accuracy of a GFR estimating equation over time in people with a wide range of kidney function." American Journal of Kidney Diseases, vol. 60, no. 2, 2012, pp. 217-24. |
| Dahabreh IJ, Trikalinos TA, Lau J, Schmid C. An Empirical Assessment of Bivariate Methods for Meta-Analysis of Test Accuracy. 2012. |
| Wallace BC, Dahabreh IJ, Trikalinos TA, Lau J, Trow P and Schmid CH. "Closing the Gap Between Methodologists and End-Users: R as a Computational Back-end." Journal of Statistical Software, vol. 49, 2012, pp. 5. |
| Dahabreh IJ, Chung M, Kitsios GD, Terasawa T, Raman G, Tatsioni A, Tobar A, Lau J, Trikalinos TA, Schmid CH. Comprehensive Overview of Methods and Reporting of Meta-Analyses of Test Accuracy. 2012. |
| Jansen JP, Schmid CH, Salanti G. "Directed acyclic graphs can help understand bias in indirect and mixed treatment comparisons." American Journal of Kidney Diseases, vol. 65, no. 7, 2012, pp. 798-807. |
| Inker LA, Schmid CH, Tighiouart H, Eckfeldt JH, Feldman HI, Greene T, Kusek JW, Manzi J, Van Lente F, Zhang YL, Coresh J, Levey AS, CKD-EPI Investigators. "Estimating glomerular filtration rate from serum creatinine and cystatin C." New England Journal of Medicine, vol. 367, no. 1, 2012, pp. 20-9. |
| Zintzaras E, Doxani C, Mprotsis T, Schmid CH and Hadjigeorgiou GM. "Network analysis of randomized controlled trials in multiple sclerosis." Clinical Therapeutics, vol. 34, 2012, pp. 857-869. |
| Inker LA, Wyatt C, Creamer R, Hellinger J, Hotta M, Leppo M, Levey AS, Okparavero A, Graham H, Savage K, Schmid CH, Tighiouart H, Wallach F, Krishnasami Z. "Performance of creatinine and cystatin C GFR estimating equations in an HIV-positive population on antiretrovirals." JAIDS Journal of Acquired Immune Deficiency Syndromes, vol. 61, no. 3, 2012, pp. 302-9. |
| Salanti G, Schmid CH. "Research Synthesis Methods special issue on network meta-analysis: introduction from the editors." Research Synthesis Methods, vol. 3, no. 2, 2012, pp. 69-70. |
| Gatsonis C, Carlos R, Gareen I, Gorelick J, Kessler L, Lau J, Rutter C, Schmid C, Tosteson ANA, Trikalinos T. "Standards in the Design, Conduct and Evaluation of Diagnostic Testing For Use in Patient Centered Outcomes Research." Patient Centered Outcomes Research Institute, 2012. |
| Wallace BC, Small K, Brodley CE, Lau J, Schmid CH, Bertram L, Lill CM, Cohen JT, Trikalinos TA. "Toward modernizing the systematic review pipeline in genetics: efficient updating via data mining." Genet Med, vol. 14, no. 7, 2012, pp. 663-9. |
| Askling J, Fahrbach K, Nordstrom B, Ross S, Schmid CH and Symmons D. "Cancer risk with tumor necrosis factor (TNF) inhibitors: meta-analysis of randomized controlled trials of adalimumab, etanercept and infliximab using patient level data." Pharmacoepidemiology and Drug Safety, vol. 20, 2011, pp. 119-130. |
| Tangri N, Stevens LA, Schmid CH, Zhang YL, Beck GJ, Greene T, Coresh J, Levey AS. "Changes in dietary protein intake has no effect on serum cystatin C levels independent of the glomerular filtration rate." Kidney International, vol. 79, no. 4, 2011, pp. 471-7. |
| Stevens LA, Claybon MA, Schmid CH, Chen J, Horio M, Imai E, Nelson RG, Van Deventer M, Wang HY, Zuo L, Zhang YL, Levey AS. "Evaluation of the Chronic Kidney Disease Epidemiology Collaboration equation for estimating the glomerular filtration rate in multiple ethnicities." Kidney International, vol. 79, no. 5, 2011, pp. 555-62. |
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Committee on Standards for Systematic Review of Comparative Effectiveness Research.
Finding What Works in Health Care: Standards for Systematic Reviews. edited by J Eden, L Levit, A Berg and S Morton, Institute of Medicine of the National Academies, 2011.
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| Kitsios GD, Dahabreh IJ, Trikalinos TA, Schmid CH, Huggins GS, Kent DM. "Heterogeneity of the phenotypic definition of coronary artery disease and its impact on genetic association studies." Circulation: Cardiovascular Genetics, vol. 4, no. 1, 2011, pp. 58-67. |
| Gordon CE, Uhlig K, Schmid CH, Levey AS, Wong JB. "Long-term viral negativity after interferon for chronic hepatitis C virus infection in hemodialysis." Clinical journal of the American Society of Nephrology : CJASN, vol. 6, no. 9, 2011, pp. 2226-34. |
| Deo A, Schmid CH, Earley A, Lau J, Uhlig K. "Loss to analysis in randomized controlled trials in CKD." American Journal of Kidney Diseases, vol. 58, no. 3, 2011, pp. 349-55. |
| Li T, Puhan MA, Vedula SS, Singh S, Dickersin K and the Ad Hoc Network Meta-analysis Methods Meeting Working Group. "Network meta-analysis-highly attractive but more methodological research is needed." BMC Medicine, vol. 9, 2011, pp. 79. |
| Sterne JA, Sutton AJ, Ioannidis JP, Terrin N, Jones DR, Lau J, Carpenter J, Rücker G, Harbord RM, Schmid CH, Tetzlaff J, Deeks JJ, Peters J, Macaskill P, Schwarzer G, Duval S, Altman DG, Moher D, Higgins JP. "Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials." BMJ, vol. 343, 2011, pp. d4002. |
| Bannuru RR, Natov NS, Dasi UR, Schmid CH, McAlindon TE. "Therapeutic trajectory following intra-articular hyaluronic acid injection in knee osteoarthritis--meta-analysis." Osteoarthritis and Cartilage, vol. 19, no. 6, 2011, pp. 611-9. |
| Bannuru, R.R., Natov, N.S., Dasi, U.R., Schmid, C.H., McAlindon, T.E. "540 THERAPEUTIC TRAJECTORY FOLLOWING INTRA-ARTICULAR HYALURONIC ACID INJECTION IN KNEE OSTEOARTHRITIS: META-ANALYSIS." Osteoarthritis and Cartilage, vol. 18, 2010, pp. S242-S243. |
| Wang C, Schmid CH, Rones R, Kalish R, Yinh J, Goldenberg DL, Lee Y, McAlindon T. "A randomized trial of tai chi for fibromyalgia." New England Journal of Medicine, vol. 363, no. 8, 2010, pp. 743-54. |
| Stevens LA, Schmid CH, Greene T, Zhang YL, Beck GJ, Froissart M, Hamm LL, Lewis JB, Mauer M, Navis GJ, Steffes MW, Eggers PW, Coresh J, Levey AS. "Comparative performance of the CKD Epidemiology Collaboration (CKD-EPI) and the Modification of Diet in Renal Disease (MDRD) Study equations for estimating GFR levels above 60 mL/min/1.73 m2." American Journal of Kidney Diseases, vol. 56, no. 3, 2010, pp. 486-95. |
| Stevens LA, Schmid CH, Zhang YL, Coresh J, Manzi J, Landis R, Bakoush O, Contreras G, Genuth S, Klintmalm GB, Poggio E, Rossing P, Rule AD, Weir MR, Kusek J, Greene T, Levey AS. "Development and validation of GFR-estimating equations using diabetes, transplant and weight." Nephrol. Dial. Transplant., vol. 25, no. 2, 2010, pp. 449-57. |
| Zucker DR, Deo A, Schmid CH. "Dialysis research and N-of-1 trials: made for each other?." American Journal of Kidney Diseases, vol. 55, no. 4, 2010, pp. 635-8. |
| Lipsey MW, Schmid CH. "From the Editors." Research Synthesis Methods, vol. 1, no. 1, 2010, pp. 1. |
| Zucker DR, Ruthazer R, Schmid CH. "Individual (N-of-1) trials can be combined to give population comparative treatment effect estimates: methodologic considerations." American Journal of Kidney Diseases, vol. 63, no. 12, 2010, pp. 1312-23. |
| Wallace BC, Trikalinos TA, Lau J, Brodley C, Schmid CH. "Semi-automated screening of biomedical citations for systematic reviews." BMC Bioinformatics, vol. 11, 2010, pp. 55. |
| Wang C, Bannuru R, Ramel J, Kupelnick B, Scott T, Schmid CH. "Tai Chi on psychological well-being: systematic review and meta-analysis." BMC Complementary and Alternative Medicine, vol. 10, 2010, pp. 23. |
| Bannuru, R.R., Natov, N.S., Obadan, I.E., Schmid, C.H., McAlindon, T.E. "501 RELATIVE EFFICACY OF HYALURONIC ACID VERSUS CORTICOSTEROIDS IN THE TREATMENT OF KNEE OSTEOARTHRITIS: META-ANALYSIS." Osteoarthritis and Cartilage, vol. 17, 2009, pp. S269-S270. |
| Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF 3rd, Feldman HI, Kusek JW, Eggers P, Van Lente F, Greene T, Coresh J, CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration). "A new equation to estimate glomerular filtration rate." Annals of Internal Medicine, vol. 150, no. 9, 2009, pp. 604-12. |
| Marques, A., Shaw, P., Schmid, C. H., Steere, A., Kaplan, R. F., Hassett, A., Shapiro, E., Wormser, G. P., Fallon, B. A., Petkova, E., Keilp, J. G., Slavov, I., Maloney, E. L., Halperin, J. J., Fallon, B. A., Szantyr, B. M., Halperin, J. J., Maloney, E. "A RANDOMIZED, PLACEBO-CONTROLLED TRIAL OF REPEATED IV ANTIBIOTIC THERAPY FOR LYME ENCEPHALOPATHY PROLONGED LYME DISEASE TREATMENT: ENOUGH IS ENOUGH." Neurology, vol. 72, no. 4, 2009, pp. 383-386. |
| Stevens LA, Nolin TD, Richardson MM, Feldman HI, Lewis JB, Rodby R, Townsend R, Okparavero A, Zhang YL, Schmid CH, Levey AS, Chronic Kidney Disease Epidemiology Collaboration. "Comparison of drug dosing recommendations based on measured GFR and kidney function estimating equations." American Journal of Kidney Diseases, vol. 54, no. 1, 2009, pp. 33-42. |
| Stevens LA, Schmid CH, Greene T, Li L, Beck GJ, Joffe MM, Froissart M, Kusek JW, Zhang YL, Coresh J, Levey AS. "Factors other than glomerular filtration rate affect serum cystatin C levels." Kidney International, vol. 75, no. 6, 2009, pp. 652-60. |
| Gordon CE, Uhlig K, Lau J, Schmid CH, Levey AS, Wong JB. "Interferon for hepatitis C virus in hemodialysis--an individual patient meta-analysis of factors associated with sustained virological response." Clinical journal of the American Society of Nephrology : CJASN, vol. 4, no. 9, 2009, pp. 1449-58. |
| Wallace BC, Schmid CH, Lau J, Trikalinos TA. "Meta-Analyst: software for meta-analysis of binary, continuous and diagnostic data." BMC medical research methodology, vol. 9, 2009, pp. 80. |
| Stoycheff N, Stevens LA, Schmid CH, Tighiouart H, Lewis J, Atkins RC, Levey AS. "Nephrotic syndrome in diabetic kidney disease: an evaluation and update of the definition." American Journal of Kidney Diseases, vol. 54, no. 5, 2009, pp. 840-9. |
| Wang C, Schmid CH, Hibberd PL, Kalish R, Roubenoff R, Rones R, McAlindon T. "Tai Chi is effective in treating knee osteoarthritis: a randomized controlled trial." Arthritis and rheumatism, vol. 61, no. 11, 2009, pp. 1545-53. |
| Bannuru RR, Natov NS, Obadan IE, Price LL, Schmid CH, McAlindon TE. "Therapeutic trajectory of hyaluronic acid versus corticosteroids in the treatment of knee osteoarthritis: a systematic review and meta-analysis." Arthritis and rheumatism, vol. 61, no. 12, 2009, pp. 1704-11. |
| Wang, C., Schmid, C., Hibberd, P., Kalish, R., Roubenoff, R., Rones, R., Okparavero, A., McAlindon, T. "A46 TAI CHI IS EFFECTIVE IN TREATING KNEE OSTEOARTHRITIS: A RANDOMIZED CONTROLLED TRIAL." Osteoarthritis and Cartilage, vol. 16, 2008, pp. S32-S33. |
| Wang C, de Pablo P, Chen X, Schmid C, McAlindon T. "Acupuncture for pain relief in patients with rheumatoid arthritis: a systematic review." Arthritis and rheumatism, vol. 59, no. 9, 2008, pp. 1249-56. |
| Drees M, Snydman DR, Schmid CH, Barefoot L, Hansjosten K, Vue PM, Cronin M, Nasraway SA, Golan Y. "Antibiotic exposure and room contamination among patients colonized with vancomycin-resistant enterococci." Infection Control & Hospital Epidemiology, vol. 29, no. 8, 2008, pp. 709-15. |
| Quach LA, Wanke CA, Schmid CH, Gorbach SL, Mwamburi DM, Mayer KH, Spiegelman D, Tang AM. "Drug use and other risk factors related to lower body mass index among HIV-infected individuals." Drug and Alcohol Dependence, vol. 95, no. 1-2, 2008, pp. 30-6. |
| Stevens LA, Coresh J, Schmid CH, Feldman HI, Froissart M, Kusek J, Rossert J, Van Lente F, Bruce RD 3rd, Zhang YL, Greene T, Levey AS. "Estimating GFR using serum cystatin C alone and in combination with serum creatinine: a pooled analysis of 3,418 individuals with CKD." American Journal of Kidney Diseases, vol. 51, no. 3, 2008, pp. 395-406. |
| Stevens LA, Zhang Y, Schmid CH. "Evaluating the performance of equations for estimating glomerular filtration rate." Journal of nephrology, vol. 21, no. 6, 2008, pp. 797-807. |
| Eggleston K, Shen YC, Lau J, Schmid CH, Chan J. "Hospital ownership and quality of care: what explains the different results in the literature?." Health economics, vol. 17, no. 12, 2008, pp. 1345-62. |
| Gordon CE, Uhlig K, Lau J, Schmid CH, Levey AS, Wong JB. "Interferon treatment in hemodialysis patients with chronic hepatitis C virus infection: a systematic review of the literature and meta-analysis of treatment efficacy and harms." American Journal of Kidney Diseases, vol. 51, no. 2, 2008, pp. 263-77. |
| Rasmussen SA, Chu SY, Kim SY, Schmid CH, Lau J. "Maternal obesity and risk of neural tube defects: a metaanalysis." American Journal of Obstetrics and Gynecology, vol. 198, no. 6, 2008, pp. 611-9. |
| Chu, S.Y., Kim, S.Y., Lau, J., Schmid, C.H., Dietz, P.M., Callaghan, W.M., Curtis, K.M. "Maternal Obesity and Risk of Stillbirth: A Meta-analysis." Obstetric Anesthesia Digest, vol. 28, no. 2, 2008, pp. 70-71. |
| Rao SR, Graubard BI, Schmid CH, Morton SC, Louis TA, Zaslavsky A and Finkelstein DM. "Meta-Analysis of Survey Data: Application to Health Services Research." Health Services and Outcomes Research Methodology, vol. 8, 2008, pp. 98-114. |
| Drees M, Snydman DR, Schmid CH, Barefoot L, Hansjosten K, Vue PM, Cronin M, Nasraway SA, Golan Y. "Prior environmental contamination increases the risk of acquisition of vancomycin-resistant enterococci." Clinical Infectious Diseases, vol. 46, no. 5, 2008, pp. 678-85. |
| Rhee MS, Schmid CH, Stevens LA, Forrester JE. "Risk factors for proteinuria in HIV-infected and -uninfected Hispanic drug users." American Journal of Kidney Diseases, vol. 52, no. 4, 2008, pp. 683-90. |
| Wang C, Schmid CH, Hibberd PL, Kalish R, Roubenoff R, Rones R, Okparavero A, McAlindon T. "Tai Chi for treating knee osteoarthritis: designing a long-term follow up randomized controlled trial." BMC Musculoskeletal Disorders, vol. 9, 2008, pp. 108. |
| Peter I, Huggins GS, Shearman AM, Pollak A, Schmid CH, Cupples LA, Demissie S, Patten RD, Karas RH, Housman DE, Mendelsohn ME, Vasan RS, Benjamin EJ. "Age-related changes in echocardiographic measurements: association with variation in the estrogen receptor-alpha gene." Hypertension, vol. 49, no. 5, 2007, pp. 1000-6. |
| McAlindon T, Formica M, Schmid CH, Fletcher J. "Changes in barometric pressure and ambient temperature influence osteoarthritis pain." The American Journal of Medicine, vol. 120, no. 5, 2007, pp. 429-34. |
| Hagadorn, J I, Richardson, D K, Schmid, C H, Cole, C H. "Cumulative illness severity and progression from moderate to severe retinopathy of prematurity." Journal of perinatology : official journal of the California Perinatal Association, vol. 27, no. 8, 2007, pp. 502-509. |
| Prata MM, Dos Santos JP, Hegbrant J, Schmid CH, Pereira BJ, Wald R. "Dose requirements among hemodialysis patients treated with darbepoetin-alpha or epoetin-beta." Nephron. Clinical practice, vol. 107, no. 2, 2007, pp. c50-5. |
| Stevens LA, Coresh J, Feldman HI, Greene T, Lash JP, Nelson RG, Rahman M, Deysher AE, Zhang YL, Schmid CH, Levey AS. "Evaluation of the modification of diet in renal disease study equation in a large diverse population." Journal of the American Society of Nephrology, vol. 18, no. 10, 2007, pp. 2749-57. |
| Shen YC, Eggleston K, Lau J, Schmid CH. "Hospital ownership and financial performance: what explains the different findings in the empirical literature?." INQUIRY: The Journal of Health Care Organization, Provision, and Financing, vol. 44, no. 1, 2007, pp. 41-68. |
| Stevens LA, Manzi J, Levey AS, Chen J, Deysher AE, Greene T, Poggio ED, Schmid CH, Steffes MW, Zhang YL, Van Lente F, Coresh J. "Impact of creatinine calibration on performance of GFR estimating equations in a pooled individual patient database." American Journal of Kidney Diseases, vol. 50, no. 1, 2007, pp. 21-35. |
| Chu SY, Kim SY, Schmid CH, Dietz PM, Callaghan WM, Lau J, Curtis KM. "Maternal obesity and risk of cesarean delivery: a meta-analysis." Obesity Reviews, vol. 8, no. 5, 2007, pp. 385-94. |
| Chu SY, Callaghan WM, Kim SY, Schmid CH, Lau J, England LJ, Dietz PM. "Maternal obesity and risk of gestational diabetes mellitus." Diabetes Care, vol. 30, no. 8, 2007, pp. 2070-6. |
| Chu SY, Kim SY, Lau J, Schmid CH, Dietz PM, Callaghan WM, Curtis KM. "Maternal obesity and risk of stillbirth: a metaanalysis." American Journal of Obstetrics and Gynecology, vol. 197, no. 3, 2007, pp. 223-8. |
| Uhlig K, Menon V, Schmid CH. "Recommendations for reporting of clinical research studies." American Journal of Kidney Diseases, vol. 49, no. 1, 2007, pp. 3-7. |
| Kourtis AP, Schmid CH, Jamieson DJ, Lau J. "Use of antiretroviral therapy in pregnant HIV-infected women and the risk of premature delivery: a meta-analysis." AIDS, vol. 21, no. 5, 2007, pp. 607-15. |
| Hagadorn JI, Furey AM, Nghiem T-H, Schmid CH, Phelps DL, Pillers DM and Cole CH. "Achieved Versus Intended Pulse Oximeter Saturation in Infants Less Than 28 Weeks Gestation: The AVIOx Study." Pediatrics, vol. 118, 2006, pp. 1574-1582. |
| Demissie S, Cupples LA, Shearman AM, Gruenthal KM, Peter I, Schmid CH, Karas RH, Housman DE, Mendelsohn ME, Ordovas JM. "Estrogen receptor-alpha variants are associated with lipoprotein size distribution and particle levels in women: the Framingham Heart Study." Atherosclerosis, vol. 185, no. 1, 2006, pp. 210-8. |
| Eggleston K, Shen Y-C, Lau J, Schmid CH and Chan J. "Hospital Ownership and Quality of Care: What Explains the Different Results?." 2006. |
| Zucker DR, Ruthazer R, Schmid CH, Feuer JM, Fischer PA, Kieval RI, Mogavero N, Rapoport RJ, Selker HP, Stotsky SA, Winston E, Goldenberg DL. "Lessons learned combining N-of-1 trials to assess fibromyalgia therapies." The Journal of Rheumatology, vol. 33, no. 10, 2006, pp. 2069-77. |
| Lau J, Ioannidis JP, Terrin N, Schmid CH, Olkin I. "The case of the misleading funnel plot." BMJ, vol. 333, no. 7568, 2006, pp. 597-600. |
| Klempner MS, Wormser GH, Wade K, Trevino RP, Tang J, Kaslow RA, Schmid C. "A case-control study to examine HLA haplotype associations in patients with posttreatment chronic Lyme disease." The Journal of Infectious Diseases, vol. 192, no. 6, 2005, pp. 1010-3. |
| Peter I, Shearman AM, Vasan RS, Zucker DR, Schmid CH, Demissie S, Cupples LA, Kuvin JT, Karas RH, Mendelsohn ME, Housman DE, Benjamin EJ. "Association of estrogen receptor beta gene polymorphisms with left ventricular mass and wall thickness in women." American Journal of Hypertension, vol. 18, no. 11, 2005, pp. 1388-95. |
| Tatsioni A, Zarin DA, Aronson N, Samson DJ, Flamm CR, Schmid C, Lau J. "Challenges in systematic reviews of diagnostic technologies." Annals of Internal Medicine, vol. 142, no. 12 Pt 2, 2005, pp. 1048-55. |
| JAFAR, T, ISLAM, M, POULTER, N, HATCHER, J, SCHMID, C, LEVEY, A, CHATURVEDI, N. "Children in South Asia have higher body mass adjusted blood pressure levels than Caucasian children in the United States -a comparative study." American Journal of Hypertension, vol. 18, no. 5, 2005, pp. A109-A109. |
| Jafar TH, Islam M, Poulter N, Hatcher J, Schmid CH, Levey AS, Chaturvedi N. "Children in South Asia have higher body mass-adjusted blood pressure levels than white children in the United States: a comparative study." Circulation, vol. 111, no. 10, 2005, pp. 1291-7. |
| Olsen IE, Richardson DK, Schmid CH, Ausman LM, Dwyer JT. "Dietitian Involvement in the Neonatal Intensive Care Unit: More Is Better." Journal of the American Dietetic Association, vol. 105, 2005, pp. 1224-1230. |
| Wang C, Roubenoff R, Lau J, Kalish R, Schmid CH, Tighiouart H, Rones R, Hibberd PL. "Effect of Tai Chi in adults with rheumatoid arthritis." Rheumatology (Oxford, England), vol. 44, no. 5, 2005, pp. 685-7. |
| Shen Y-C, Eggleston K, Lau J and Schmid C. "Hospital Ownership and Financial Performance: A Qunatitative Research Review." 2005. |
| Terrin N, Schmid CH, Lau J. "In an empirical evaluation of the funnel plot, researchers could not visually identify publication bias." American Journal of Kidney Diseases, vol. 58, no. 9, 2005, pp. 894-901. |
| Norris SL, Zhang X, Avenell A, Gregg E, Bowman B, Schmid CH, Lau J. "Long-term effectiveness of weight-loss interventions in adults with pre-diabetes: a review." American Journal of Preventive Medicine, vol. 28, no. 1, 2005, pp. 126-39. |
| Norris SL, Zhang X, Avenell A, Gregg E, Brown TJ, Schmid CH, Lau J. "Long-term non-pharmacologic weight loss interventions for adults with type 2 diabetes." The Cochrane database of systematic reviews, no. 2, 2005, pp. CD004095. |
| Norris SL, Zhang X, Avenell A, Gregg E, Schmid CH, Lau J. "Long-term non-pharmacological weight loss interventions for adults with prediabetes." The Cochrane database of systematic reviews, no. 2, 2005, pp. CD005270. |
| Norris SL, Zhang X, Avenell A, Gregg E, Schmid CH, Lau J. "Pharmacotherapy for weight loss in adults with type 2 diabetes mellitus." The Cochrane database of systematic reviews, no. 1, 2005, pp. CD004096. |
| Norris, None, Zhang, None, Avenell, None, Gregg, None, Schmid, None, Lau, None. "Pharmakotherapie zur Gewichtsabnahme bei Erwachsenen mit Typ-2-Diabetes mellitus." PRAXIS, vol. 94, no. 41, 2005, pp. 1606-1606. |
| Jafar TH, Chaturvedi N, Hatcher J, Khan I, Rabbani A, Khan AQ, Portman R, Schmid CH, Levey AS. "Proteinuria in South Asian children: prevalence and determinants." Pediatric Nephrology, vol. 20, no. 10, 2005, pp. 1458-65. |
| Jafar TH, Schmid CH, Levey AS. "Serum creatinine as marker of kidney function in South Asians: a study of reduced GFR in adults in Pakistan." Journal of the American Society of Nephrology, vol. 16, no. 5, 2005, pp. 1413-9. |
| Jafar TH, Stark PC, Schmid CH, Strandgaard S, Kamper AL, Maschio G, Becker G, Perrone RD, Levey AS, ACE Inhibition in Progressive Renal Disease (AIPRD) Study Group. "The effect of angiotensin-converting-enzyme inhibitors on progression of advanced polycystic kidney disease." Kidney International, vol. 67, no. 1, 2005, pp. 265-71. |
| Shearman AM, Demissie S, Cupples LA, Peter I, Schmid CH, Ordovas JM, Mendelsohn ME, Housman DE. "Tobacco smoking, estrogen receptor alpha gene variation and small low density lipoprotein level." Human molecular genetics, vol. 14, no. 16, 2005, pp. 2405-13. |
| Peter I, Shearman AM, Zucker DR, Schmid CH, Demissie S, Cupples LA, Larson MG, Vasan RS, D'Agostino RB, Karas RH, Mendelsohn ME, Housman DE, Levy D. "Variation in estrogen-related genes and cross-sectional and longitudinal blood pressure in the Framingham Heart Study." Journal of hypertension, vol. 23, no. 12, 2005, pp. 2193-200. |
| Gill CJ, Sabin L, Schmid CH. "Why clinicians are natural bayesians." BMJ, vol. 330, no. 7499, 2005, pp. 1080-3. |
| Schmid CH, Cappelleri JC, Lau J. "Bayesian methods to improve sample size approximations." Methods in enzymology, vol. 383, 2004, pp. 406-27. |
| Norris SL, Zhang X, Avenell A, Gregg E, Schmid CH, Kim C, Lau J. "Efficacy of pharmacotherapy for weight loss in adults with type 2 diabetes mellitus: a meta-analysis." Arch Intern Med, vol. 164, no. 13, 2004, pp. 1395-404. |
| Jafar TH, Levey AS, White FM, Gul A, Jessani S, Khan AQ, Jafary FH, Schmid CH, Chaturvedi N. "Ethnic differences and determinants of diabetes and central obesity among South Asians of Pakistan." Diabetic medicine : a journal of the British Diabetic Association, vol. 21, no. 7, 2004, pp. 716-23. |
| Norris SL, Zhang X, Avenell A, Gregg E, Bowman B, Serdula M, Brown TJ, Schmid CH, Lau J. "Long-term effectiveness of lifestyle and behavioral weight loss interventions in adults with type 2 diabetes: a meta-analysis." The American Journal of Medicine, vol. 117, no. 10, 2004, pp. 762-74. |
| Schmid CH, Stark PC, Berlin JA, Landais P, Lau J. "Meta-regression detected associations between heterogeneous treatment effects and study-level, but not patient-level, factors." American Journal of Kidney Diseases, vol. 57, no. 7, 2004, pp. 683-97. |
| Fleming RV, Marques AR, Klempner MS, Schmid CH, Dally LG, Martin DS, Philipp MT. "Pre-treatment and post-treatment assessment of the C(6) test in patients with persistent symptoms and a history of Lyme borreliosis." European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, vol. 23, no. 8, 2004, pp. 615-8. |
| Terrin N, Schmid CH, Lau J, Olkin I. "Adjusting for publication bias in the presence of heterogeneity." Statistics in Medicine, vol. 22, no. 13, 2003, pp. 2113-26. |
| Shearman AM, Cupples LA, Demissie S, Peter I, Schmid CH, Karas RH, Mendelsohn ME, Housman DE and Levy D. "Association between estrogen receptor a gene variation and cardiovascular disease." JAMA, vol. 290, 2003, pp. 2263-2270. |
| Kaplan RF, Trevino RP, Johnson GM, Levy L, Dornbush R, Hu LT, Evans J, Weinstein A, Schmid CH and Klempner MS. "Cognitive Function in Post-treatment Lyme Disease: Do additional antibiotics help?." Neurology, vol. 60, 2003, pp. 1916-1922. |
| Schmid CH, Landa M, Jafar TH, Giatras I, Karim T, Reddy M, Stark PC, Levey AS, Angiotensin-Converting Enzyme Inhibition in Progressive Renal Disease (AIPRD) Study Group. "Constructing a database of individual clinical trials for longitudinal analysis." Controlled clinical trials, vol. 24, no. 3, 2003, pp. 324-40. |
| Jafar TH, Chaturvedi N, Gul A, Khan AQ, Schmid CH, Levey AS. "Ethnic differences and determinants of proteinuria among South Asian subgroups in Pakistan." Kidney International, vol. 64, no. 4, 2003, pp. 1437-44. |
| Jafar TH, Levey AS, Jafary FH, White F, Gul A, Rahbar MH, Khan AQ, Hattersley A, Schmid CH, Chaturvedi N. "Ethnic subgroup differences in hypertension in Pakistan." Journal of hypertension, vol. 21, no. 5, 2003, pp. 905-12. |
| Terrin N, Schmid CH, Griffith JL, D'Agostino RB, Selker HP. "External validity of predictive models: a comparison of logistic regression, classification trees, and neural networks." American Journal of Kidney Diseases, vol. 56, no. 8, 2003, pp. 721-9. |
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Schmid CH, Brown EN and Ogren JM.
"Modeling Daily Growth in children." 2003, pp. 3698-3705.
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Stark PC, Levey AS and Schmid CH.
"Predictors of Change in Glomerular Filtration Rate Among Nondiabetic Patients with Chronic Kidney Disease." 2003, pp. 4047-4049.
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| Jafar TH, Stark PC, Schmid CH, Landa M, Maschio G, de Jong PE, de Zeeuw D, Shahinfar S, Toto R, Levey AS, AIPRD Study Group. "Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis." Annals of Internal Medicine, vol. 139, no. 4, 2003, pp. 244-52. |
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Nguyen DP, Schmid CH, Klerman EB, Adler G and Brown EN.
"Stochastic Deconvolution of Neuroendocrine Hormone Rhythms." ASA Proceedings of the Joint Statistical Meetings, 2003, pp. 3025-3032.
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| Olsen IE, Richardson DK, Schmid CH, Ausman LM, Dwyer JT. "The impact of early transfer bias in a growth study among neonatal intensive care units." American Journal of Kidney Diseases, vol. 56, no. 10, 2003, pp. 998-1005. |
| Jafar TH, Schmid CH, Stark PC, Toto R, Remuzzi G, Ruggenenti P, Marcantoni C, Becker G, Shahinfar S, De Jong PE, De Zeeuw D, Kamper AL, Strangaard S, Levey AS. "The rate of progression of renal disease may not be slower in women compared with men: a patient-level meta-analysis." Nephrol. Dial. Transplant., vol. 18, no. 10, 2003, pp. 2047-53. |
| Selker HP, Raitt MH, Schmid CH, Laks MM, Beshansky JR, Griffith JL, Califf RM, Selvester RH, Maynard C, D'Agostino RB, Weaver WD. "Time-dependent predictors of primary cardiac arrest in patients with acute myocardial infarction." The American Journal of Cardiology, vol. 91, no. 3, 2003, pp. 280-6. |
| Balk EM, Bonis PA, Moskowitz H, Schmid CH, Ioannidis JP, Wang C, Lau J. "Correlation of quality measures with estimates of treatment effect in meta-analyses of randomized controlled trials." JAMA, vol. 287, no. 22, 2002, pp. 2973-82. |
| Jafar TH, Schmid CH, Levey AS. "Effect of angiotensin-converting enzyme inhibitors on progression of nondiabetic renal disease." Annals of Internal Medicine, vol. 137, no. 4, 2002, pp. 298-9. |
| Jaber BL, Lau J, Schmid CH, Karsou SA, Levey AS, Pereira BJ. "Effect of biocompatibility of hemodialysis membranes on mortality in acute renal failure: a meta-analysis." Clinical Nephrology, vol. 57, no. 4, 2002, pp. 274-82. |
| Berlin JA, Santanna J, Schmid CH, Szczech LA, Feldman HI, Anti-Lymphocyte Antibody Induction Therapy Study Group. "Individual patient- versus group-level data meta-regressions for the investigation of treatment effect modifiers: ecological bias rears its ugly head." Statistics in Medicine, vol. 21, no. 3, 2002, pp. 371-87. |
| Olsen IE, Richardson DK, Schmid CH, Ausman LM and Dwyer JT. "Intersite Differences in Weight Growth Velocity of Extremely Premature Infants." Pediatrics, vol. 110, 2002, pp. 1125-1132. |
| Kent DM, Schmid CH, Lau J, Selker HP. "Is primary angioplasty for some as good as primary angioplasty for all?." J GEN INTERN MED, vol. 17, no. 12, 2002, pp. 887-94. |
| Norris SL, Lau J, Smith SJ, Schmid CH, Engelgau MM. "Self-management education for adults with type 2 diabetes: a meta-analysis of the effect on glycemic control." Diabetes Care, vol. 25, no. 7, 2002, pp. 1159-71. |
| Jafar TH, Schmid CH, Landa M, Giatras I, Toto R, Remuzzi G, Maschio G, Brenner BM, Kamper A, Zucchelli P, Becker G, Himmelmann A, Bannister K, Landais P, Shahinfar S, de Jong PE, de Zeeuw D, Lau J, Levey AS. "Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data." Annals of Internal Medicine, vol. 135, no. 2, 2001, pp. 73-87. |
| Klempner MS, Schmid CH, Hu L, Steere AC, Johnson G, McCloud B, Noring R, Weinstein A. "Intralaboratory reliability of serologic and urine testing for Lyme disease." The American Journal of Medicine, vol. 110, no. 3, 2001, pp. 217-9. |
| Schmid CH. "Marginal and dynamic regression models for longitudinal data." Statistics in Medicine, vol. 20, no. 21, 2001, pp. 3295-311. |
| Schmid CH, Griffith JL, Terrin N and D’Agostino RB Sr. "Predictive Performance of Missing Data Methods for Logistic Regression, Classification Trees and Neural Networks." Journal of Statistical Computation and Simulation, vol. 71, 2001, pp. 115-140. |
| Jafar TH, Stark PC, Schmid CH, Landa M, Maschio G, Marcantoni C, de Jong PE, de Zeeuw D, Shahinfar S, Ruggenenti P, Remuzzi G, Levey AS, AIPRD Study Group. Angiotensin-Converting Enzymne Inhibition and Progression of Renal Disease. "Proteinuria as a modifiable risk factor for the progression of non-diabetic renal disease." Kidney International, vol. 60, no. 3, 2001, pp. 1131-40. |
| Klempner MS, Hu LT, Evans J, Schmid CH, Johnson GM, Trevino RP, Norton D, Levy L, Wall D, McCall J, Kosinski M, Weinstein A. "Two controlled trials of antibiotic treatment in patients with persistent symptoms and a history of Lyme disease." New England Journal of Medicine, vol. 345, no. 2, 2001, pp. 85-92. |
| Schmid CH. "Using Bayesian Inference to Perform Meta-Analysis." Evaluation and the Health Professions, vol. 24, 2001, pp. 165-189. |
| Schmid CH, Brown EN. "Bayesian hierarchical models." Methods in enzymology, vol. 321, 2000, pp. 305-30. |
| Athienites NV, Miskulin DC, Fernandez G, Bunnapradist S, Simon G, Landa M, Schmid CH, Greenfield S, Levey AS, Meyer KB. "Comorbidity assessment in hemodialysis and peritoneal dialysis using the index of coexistent disease." Semin Dial, vol. 13, no. 5, 2000, pp. 320-6. |
| Arbo MD, Snydman DR, Wong JB, Goldberg HS, Schmid CH, Pauker SG. "Cytomegalovirus immune globulin after liver transplantation: a cost-effectiveness analysis." Clinical transplantation, vol. 14, no. 1, 2000, pp. 19-27. |
| Engels EA, Schmid CH, Terrin N, Olkin I, Lau J. "Heterogeneity and statistical significance in meta-analysis: an empirical study of 125 meta-analyses." Statistics in Medicine, vol. 19, no. 13, 2000, pp. 1707-28. |
| Balakrishnan VS, Schmid CH, Jaber BL, Natov SN, King AJ, Pereira BJ. "Interleukin-1 receptor antagonist synthesis by peripheral blood mononuclear cells: a novel predictor of morbidity among hemodialysis patients." Journal of the American Society of Nephrology, vol. 11, no. 11, 2000, pp. 2114-21. |
| Ioannidis JP, Schmid CH, Lau J. "Meta-analysis in hematology and oncology." Hematology/oncology clinics of North America, vol. 14, no. 4, 2000, pp. 973-91. |
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Schmid CH and Brown EN.
"A Probability Model for Saltatory Growth." Saltation and Stasis in Human Growth and Development: Evidence, Methods and Theory, edited by M Lampl, Smith-Gordon, 1999, pp. 121-131.
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| Kaplan MM, Schmid C, Provenzale D, Sharma A, Dickstein G, McKusick A. "A prospective trial of colchicine and methotrexate in the treatment of primary biliary cirrhosis." Gastroenterology, vol. 117, no. 5, 1999, pp. 1173-80. |
| Engels EA, Ellis CA, Supran SE, Schmid CH, Barza M, Schenkein DP, Koc Y, Miller KB, Wong JB. "Early infection in bone marrow transplantation: quantitative study of clinical factors that affect risk." Clinical Infectious Diseases, vol. 28, no. 2, 1999, pp. 256-66. |
| Schmid CH. "Exploring Heterogeneity in Randomized Trials via Meta-Analysis." vol. 33, 1999, pp. 211-224. |
| Wazer DE, Jabro G, Ruthazer R, Schmid C, Safaii H, Schmidt-Ullrich RK. "Extent of margin positivity as a predictor for local recurrence after breast conserving irradiation." Radiation oncology investigations, vol. 7, no. 2, 1999, pp. 111-7. |
| Natov SN, Lau JY, Ruthazer R, Schmid CH, Levey AS, Pereira BJ. "Hepatitis C virus genotype does not affect patient survival among renal transplant candidates. The New England Organ Bank Hepatitis C Study Group." Kidney International, vol. 56, no. 2, 1999, pp. 700-6. |
| Schmid CH, Whiting G, Cory D, Ross SD and Chalmers TC. "Omeprazole Plus Antibiotics in the Eradication of Helicobacter pylori Infection: A Meta-Regression Analysis of Randomized, Controlled Trials." American journal of therapeutics, vol. 6, 1999, pp. 25-36. |
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Schmid CH.
"Regression Models for Longitudinal Data with Missing Covariate Values." Proceedings of the Section on Statistics in Epidemiology, American Statistical Association, 1999, pp. 25-34.
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| Stason WB, Schmid CH, Niedzwiecki D, Whiting GW, Caubet JF, Cory D, Luo D, Ross SD, Chalmers TC. "Safety of nifedipine in angina pectoris: a meta-analysis." Hypertension, vol. 33, no. 1, 1999, pp. 24-31. |
| Schmid CH, Lau J, McIntosh MW, Cappelleri JC. "An empirical study of the effect of the control rate as a predictor of treatment efficacy in meta-analysis of clinical trials." Statistics in Medicine, vol. 17, no. 17, 1998, pp. 1923-42. |
| Levey AS, Schmid CH, Lau J. "Antilymphocyte antibodies, renal transplantation, and meta-analysis." Annals of Internal Medicine, vol. 128, no. 10, 1998, pp. 863-5. |
| King AJ, Kehayias JJ, Roubenoff R, Schmid CH, Pereira BJ. "Cytokine production and nutritional status in hemodialysis patients." The International journal of artificial organs, vol. 21, no. 1, 1998, pp. 4-11. |
| Pereira BJ, Natov SN, Bouthot BA, Murthy BV, Ruthazer R, Schmid CH, Levey AS. "Effects of hepatitis C infection and renal transplantation on survival in end-stage renal disease. The New England Organ Bank Hepatitis C Study Group." Kidney International, vol. 53, no. 5, 1998, pp. 1374-81. |
| Wazer DE, Schmidt-Ullrich RK, Ruthazer R, Schmid CH, Graham R, Safaii H, Rothschild J, McGrath J, Erban JK. "Factors determining outcome for breast-conserving irradiation with margin-directed dose escalation to the tumor bed." International Journal of Radiation Oncology*Biology*Physics, vol. 40, no. 4, 1998, pp. 851-8. |
| Balakrishnan VS, Jaber BL, Natov SN, Cendoroglo M, King AJ, Schmid CH, Pereira BJ. "Interleukin-1 receptor antagonist synthesis by peripheral blood mononuclear cells in hemodialysis patients." Kidney International, vol. 54, no. 6, 1998, pp. 2106-12. |
|
Ioannidis JPA, Schmid CH and Lau J.
"Meta-Analysis Approaches for Epidemiologic Research on Asbestos." Current Asbestos Issues: Volume 18 of the Sourcebook for Asbestos Diseases, edited by GA Peters and BJ Peters, Charlottsville, VA, Lexis Law Publishing, 1998, pp. 93-116.
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| Schmid CH and Griffith JL. "Multivariate Classification Rules: Calibration and Discrimination." Encyclopedia of Biostatistics, New York, John Wiley and Sons, 1998, pp. 2844-2850. |
| Schmid CH. "Nuisance Parameters." Encyclopedia of Biostatistics, New York, John Wiley and Sons, 1998, pp. 3079-3080. |
| Ettinger LM, Hijazi ZM, Geggel RL, Supran SE, Cao Q and Schmid CH. "Peripheral pulmonary artery stenosis: Acute and mid-term results of high pressure balloon angioplasty." Journal of interventional cardiology, vol. 11, 1998, pp. 337-344. |
| Murthy BV, Muerhoff AS, Desai SM, Natov SN, Bouthot BA, Ruthazer R, Schmid CH, Levey AS, Mushahwar IK, Pereira BJ. "Predictors of GBV-C infection among patients referred for renal transplantation." Kidney International, vol. 53, no. 6, 1998, pp. 1769-74. |
| Natov SN, Lau JY, Bouthot BA, Murthy BV, Ruthazer R, Schmid CH, Levey AS, Pereira BJ. "Serologic and virologic profiles of hepatitis C infection in renal transplant candidates. New England Organ Bank Hepatitis C Study Group." American Journal of Kidney Diseases, vol. 31, no. 6, 1998, pp. 920-7. |
| Lau J, Ioannidis JP, Schmid CH. "Summing up evidence: one answer is not always enough." The Lancet, vol. 351, no. 9096, 1998, pp. 123-7. |
| Steere AC, Sikand VK, Meurice F, Parenti DL, Fikrig E, Schoen RT, Nowakowski J, Schmid CH, Laukamp S, Buscarino C, Krause DS. "Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant. Lyme Disease Vaccine Study Group." New England Journal of Medicine, vol. 339, no. 4, 1998, pp. 209-15. |
| Schmid CH, D'Agostino RB, Griffith JL, Beshansky JR, Selker HP. "A logistic regression model when some events precede treatment: the effect of thrombolytic therapy for acute myocardial infarction on the risk of cardiac arrest." American Journal of Kidney Diseases, vol. 50, no. 11, 1997, pp. 1219-29. |
| Zucker DR, Schmid CH, McIntosh MW, D'Agostino RB, Selker HP, Lau J. "Combining single patient (N-of-1) trials to estimate population treatment effects and to evaluate individual patient responses to treatment." American Journal of Kidney Diseases, vol. 50, no. 4, 1997, pp. 401-10. |
| Wazer DE, Kramer B, Schmid C, Ruthazer R, Ulin K, Schmidt-Ullrich R. "Factors determining outcome in patients treated with interstitial implantation as a radiation boost for breast conservation therapy." International Journal of Radiation Oncology*Biology*Physics, vol. 39, no. 2, 1997, pp. 381-93. |
| Rhodes J, Warner KG, Fulton DR, Romero BA, Schmid CH and Marx GR. "Fate of Mitral Regurgitation Following Repair of Atrioventricular Septal Defects." American Journal of Cardiology, vol. 80, 1997, pp. 1194-1197. |
| Murthy BV, Muerhoff AS, Desai SM, Lund J, Schmid CH, Levey AS, Mushahwar IK, Pereira BJ. "GB hepatitis agent in cadaver organ donors and their recipients." Transplantation, vol. 63, no. 3, 1997, pp. 346-51. |
| Murthy BV, Muerhoff AS, Desai SM, Yamaguchi J, Mushahwar IK, Schmid CH, Levey AS, Pereira BJ. "Impact of pretransplantation GB virus C infection on the outcome of renal transplantation." Journal of the American Society of Nephrology, vol. 8, no. 7, 1997, pp. 1164-73. |
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Griffith JL, Schmid CH, Terrin N and D’Agostino RB Sr.
"Impact of Sample Size and Outcome Prevalence on the Predictive Performance of Logistic Regression, Classification Trees and Neural Networks." 1997, pp. 259-264.
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| Tunis SR, Sheinhait IA, Schmid CH, Bishop DJ and Ross SD. "Lansoprazole Compared with Histamine2-Receptor Antagonists in Healing Gastric Ulcers: A Meta-Analysis." Clinical Therapeutics, vol. 19, 1997, pp. 743-757. |
| Bouthot BA, Murthy BV, Schmid CH, Levey AS, Pereira BJ. "Long-term follow-up of hepatitis C virus infection among organ transplant recipients: implications for policies on organ procurement." Transplantation, vol. 63, no. 6, 1997, pp. 849-53. |
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D’Agostino RB Sr., Griffith JL, Schmid CH and Terrin N.
"Measures for Evaluating Model Performance." Proceedings of the Biometrics Section, American Statistical Association, 1997, pp. 253-258.
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| Selker HP, Griffith JL, Beshansky JR, Schmid CH, Califf RM, D'Agostino RB, Laks MM, Lee KL, Maynard C, Selvester RH, Wagner GS, Weaver WD. "Patient-specific predictions of outcomes in myocardial infarction for real-time emergency use: a thrombolytic predictive instrument." Annals of Internal Medicine, vol. 127, no. 7, 1997, pp. 538-56. |
| Lafayette RA, Paré G, Schmid CH, King AJ, Rohrer RJ, Nasraway SA. "Pretransplant renal dysfunction predicts poorer outcome in liver transplantation." Clinical Nephrology, vol. 48, no. 3, 1997, pp. 159-64. |
| Lau J, Ioannidis JP, Schmid CH. "Quantitative synthesis in systematic reviews." Annals of Internal Medicine, vol. 127, no. 9, 1997, pp. 820-6. |
| Stason WB, Schmid CH, Niedzwiecki D, Whiting G, Cory D, Luo D, Caubet JF, Sheinhait I, Freedman R, Ross SD and Chalmers TC. "Safety of Nifedipine in Patients with Hypertension: A Meta-Analysis." Hypertension, vol. 30, 1997, pp. 7-14. |
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Schmid CH, Griffith JL, Terrin N and D’Agostino RB Sr.
"Synthesizing the Treatment of Missing Data in Logistic Regression, Classification Trees and Neural Networks." Proceedings of the Biometrics Section, American Statistical Association, 1997, pp. 265-269.
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| Wazer DE, Morr J, Erban JK, Schmid CH, Ruthazer R, Schmidt-Ullrich RK. "The effects of postradiation treatment with tamoxifen on local control and cosmetic outcome in the conservatively treated breast." Cancer, vol. 80, no. 4, 1997, pp. 732-40. |
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Terrin N, Griffith JL, Schmid CH and D’Agostino RB Sr.
"The Impact of Outliers and Distortions on the Predictive Performance of Logistic Regression, Classification Trees and Neural Networks." Proceedings of the Biometrics Section, American Statistical Association, 1997, pp. 270-275.
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| Wazer DE, Schmidt-Ullrich RK, Schmid CH, Ruthazer R, Kramer B, Safaii H, Graham R. "The value of breast lumpectomy margin assessment as a predictor of residual tumor burden." International Journal of Radiation Oncology*Biology*Physics, vol. 38, no. 2, 1997, pp. 291-9. |
|
Schmid CH and Brown EN.
"A Hierarchical Bayes Model for Human Growth." Proceedings of the Section on Bayesian Statistics, American Statistical Association, 1996, pp. 146-151.
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| Goldenberg D, Mayskiy M, Mossey C, Ruthazer R, Schmid C. "A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia." Arthritis and rheumatism, vol. 39, no. 11, 1996, pp. 1852-9. |
| Wazer DE, Gage I, Homer MJ, Krosnick SH, Schmid C. "Age-related differences in patients with nonpalpable breast carcinomas." Cancer, vol. 78, no. 7, 1996, pp. 1432-7. |
| Schmid CH. "An EM Algorithm Fitting First-Order Conditional Autoregressive Models to Longitudinal Data." Journal of the American Statistical Association, vol. 91, 1996, pp. 1322-1330. |
| Nocton JJ, Bloom BJ, Rutledge BJ, Persing DH, Logigian EL, Schmid CH and Steere AC. "Detection of Borrelia Burgdorferi DNA by Polymerase Chain Reaction in Cerebrospinal Fluid in Lyme Neuroborreliosis." The Journal of Infectious Diseases, vol. 174, 1996, pp. 623-627. |
| Lakshmipathy N, Bokesch PM, Cowen DE, Lisman SR, Schmid CH. "Environmental tobacco smoke: a risk factor for pediatric laryngospasm." Anesthesia and analgesia, vol. 82, no. 4, 1996, pp. 724-7. |
| Ioannidis JP, Cappelleri JC, Schmid CH, Lau J. "Impact of epidemic and individual heterogeneity on the population distribution of disease progression rates. An example from patient populations in trials of human immunodeficiency virus infection." American Journal of Epidemiology, vol. 144, no. 11, 1996, pp. 1074-85. |
| Pereira BJ, Natov SN, Sundaram S, Schmid CH, Trabelsi FR, Strom JA, King AJ. "Impact of single use versus reuse of cellulose dialyzers on clinical parameters and indices of biocompatibility." Journal of the American Society of Nephrology, vol. 7, no. 6, 1996, pp. 861-70. |
| Cappelleri JC, Ioannidis JP, Schmid CH, de Ferranti SD, Aubert M, Chalmers TC, Lau J. "Large trials vs meta-analysis of smaller trials: how do their results compare?." JAMA, vol. 276, no. 16, 1996, pp. 1332-8. |
| Stason W, Schmid CH, Caubet JF, Kupelnick B, Cory D, Whiting G, Chalmers TC, Ross SD. "Searching for signals: mortality and cardiovascular events in published randomized control trials of nifedipine in ischemic heart disease and hypertension." Journal of hypertension. Supplement : official journal of the International Society of Hypertension, vol. 14, no. 2, 1996, pp. S5-7. |
| Pereira BJ, Wright TL, Schmid CH, Levey AS. "A controlled study of hepatitis C transmission by organ transplantation. The New England Organ Bank Hepatitis C Study Group." The Lancet, vol. 345, no. 8948, 1995, pp. 484-7. |
| Goldenberg DL, Mossey CJ and Schmid CH. "A Model to Assess Severity and Impact of Fibromyalgia." Journal of Rheumatology, vol. 22, 1995, pp. 2313-2318. |
| Schmid CH, Cappelleri JC and Lau J. "Bayesian Methods to Improve Sample Size Approximations." Proceedings of the Section on Bayesian Statistics, American Statistical Association, 1995, pp. 89-94. |
| Lau J, Schmid CH, Chalmers TC. "Cumulative meta-analysis of clinical trials builds evidence for exemplary medical care." American Journal of Kidney Diseases, vol. 48, no. 1, 1995, pp. 45-57; discussion 59-60. |
| Werner-Wasik M, Schmid CH, Bornstein LE, Madoc-Jones H. "Increased risk of second malignant neoplasms outside radiation fields in patients with cervical carcinoma." Cancer, vol. 75, no. 9, 1995, pp. 2281-5. |
| Werner-Wasik M, Schmid CH, Bornstein L, Ball HG, Smith DM, and Madoc-Jones H. "Prognostic Factors for Local and Distant Recurrence in Stage I and II Cervical Carcinoma." Int. J. Radiation Oncology Biol. Phys., vol. 32, 1995, pp. 1309-1317. |
| Maynard C, Selker HP, Beshansky JR, Griffith JL, Schmid CH, Califf RM, D'Agostino RB, Laks MM, Lee KL, Wagner GS. "The exclusion of women from clinical trials of thrombolytic therapy: implications for developing the thrombolytic predictive instrument database." Medical decision making : an international journal of the Society for Medical Decision Making, vol. 15, no. 1, 1995, pp. 38-43. |
| Periera BJ, Wright TL, Schmid CH, Levey AS. "The impact of pretransplantation hepatitis C infection on the outcome of renal transplantation." Transplantation, vol. 60, no. 8, 1995, pp. 799-805. |
| Goldenberg DL, Kaplan KH, Nadeau MG, Brodeur C, Smith S and Schmid CH. "A Controlled Study of a Stress-Reduction, Cognitive-Behavioral Treatment Program in Fibromyalgia." Journal of Musculoskeletal Pain, vol. 2, 1994, pp. 53-66. |
| Fink JC, Schmid CH, Selker HP. "A decision aid for referring patients with systolic murmurs for echocardiography." J GEN INTERN MED, vol. 9, no. 9, 1994, pp. 479-84. |
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Schmid CH.
"A State-Space Model for Longitudinal Regression." Proceedings of the 26th Symposium on the Interface, 1994, pp. 125-129.
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| Bry JD, Belkin M, O'Donnell TF Jr, Mackey WC, Udelson JE, Schmid CH, Safran DG. "An assessment of the positive predictive value and cost-effectiveness of dipyridamole myocardial scintigraphy in patients undergoing vascular surgery." Journal of vascular surgery, vol. 19, no. 1, 1994, pp. 112-21; discussion 121-4. |
| Brown EN and Schmid CH. "Application of the Kalman Filter to Computational Problems in Statistics." Methods in Enzymology Volume 240: Numerical Computer Methods Part B, edited by ML Johnson and L Brand, New York, Academic Press, 1994, pp. 171-181. |
| Wazer DE, Erban JK, Robert NJ, Smith TJ, Marchant DJ, Schmid C, DiPetrillo T, Schmidt-Ullrich R. "Breast conservation in elderly women for clinically negative axillary lymph nodes without axillary dissection." Cancer, vol. 74, no. 3, 1994, pp. 878-83. |
| Schmid CH, Segal M and Rosner B. "Incorporating Measurement Error in the Estimation of Autoregressive Models for Longitudinal Data." Journal of Statistical Planning and Inference, vol. 42, 1994, pp. 1-18. |
| Selker HP, Beshansky JR, Schmid CH, Griffith JL, Longstreth WT Jr, O'Connor CM, Caplan LR, Massey EW, D'Agostino RB, Laks MM. "Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage. Thrombolytic Predictive Instrument (TPI) Project results." Circulation, vol. 90, no. 4, 1994, pp. 1657-61. |
| Kaelin CM, Smith TJ, Homer MJ, Taback B, Azurin D, Schmid CH and Weld L. "Safety, Accuracy, and Diagnostic Yield of Needle Localization Biopsy of the Breast Performed Using Local Anesthesia." Journal of the American College of Surgeons, vol. 179, 1994, pp. 267-272. |
| Pereira BJG, Wright TL, Schmid CH, Bryan CF, Cheung RC, Cooper ES, Hsu H, Kelly MK, Light JA, Norman DJ, Van Thiel DH, Werner BG, Wright CE, and Levey AS. "Screening and Confirmatory Testing of Cadaver Organ Donors for Hepatitis C Virus Infection: A U.S. National Collaborative Study." Kidney International, vol. 46, 1994, pp. 886-892. |
| Graham RA, Homer MJ, Sigler CJ, Safaii H, Schmid CH, Marchant DJ, Smith TJ. "The efficacy of specimen radiography in evaluating the surgical margins of impalpable breast carcinoma." American Journal of Roentgenology, vol. 162, no. 1, 1994, pp. 33-6. |
| Steere AC, Levin RE, Molloy PJ, Kalish RA, Abraham JH 3rd, Liu NY, Schmid CH. "Treatment of Lyme arthritis." Arthritis and rheumatism, vol. 37, no. 6, 1994, pp. 878-88. |
| Schmid CH, Rosner B. "A Bayesian approach to logistic regression models having measurement error following a mixture distribution." Statistics in Medicine, vol. 12, no. 12, 1993, pp. 1141-53. |
| Rhodes J, Udelson JE, Marx GR, Schmid CH, Konstam MA, Hijazi ZM, Bova SA and Fulton DR. "A New Noninvasive Method for the Estimation of Peak dP/dt." Circulation, vol. 88, 1993, pp. 2693-2699. |
| Schmidt-Ullrich RK, Wazer DE, DiPetrillo T, Marchant DJ, Smith TJ, Safaii H, Schmid C, Homer MJ. "Breast conservation therapy for early stage breast carcinoma with outstanding 10-year locoregional control rates: a case for aggressive therapy to the tumor bearing quadrant." International Journal of Radiation Oncology*Biology*Physics, vol. 27, no. 3, 1993, pp. 545-52. |
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DeGroot AS, McGowen K, Schieb RG, Schmid CH, Lieberman J and Wyler DJ.
"T Cell Responses to Mycobacterium tuberculosis Antigens in the HIV-Infected Host." Vaccines 93, Cold Spring Harbor, NY, Cold Spring Harbor Press, 1993, pp. 251-257.
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| Schmid CH. "Value Splitting: Taking the Data Apart." Fundamentals of Exploratory Analysis of Variance, edited by DC Hoaglin, F Mosteller and JW Tukey, New York, John Wiley and Sons, 1991, pp. 72-113. |
My research focuses on methods for the quantitative synthesis of information from observational and experimental studies and through meta-analysis. My team develops methods and software for meta-analysis of two or more treatments, for N-of-1 studies and for predictive models. My research seeks to develop and apply tools to further the health of patients and to design and carry out research studies to develop new treatments and new methods of delivering them. I am involved in many different clinical trials and development of predictive models.
My major research interests include development and application of Bayesian models for clinical research and development of statistical methods and computational tools for meta-analysis and N-of-1 studies. Current research focuses on methods for analyzing multivariate data in meta-analysis, development of open source meta-analysis software, development of predictive models from individual patient data collected from multiple data sources and modeling of data from single patient studies for incorporation into mobile phone and tablet applications. I also have two large projects developing statistical educational tools for professionals and clinical researchers
I see many opportunities for advancing the science of comparative effectiveness research in the coming years and believe that these will be fruitful research opportunities for both biostatistics graduate students and other collaborators in medicine, public health and other scientific disciplines doing systematic reviews. My research in meta-analysis and evidence synthesis takes place in the Center for Evidence Synthesis in Health. Our focus there revolves around the development of research methods and software tools.
Our open-source software tool Open Meta-Analyst will soon be able to carry out basic and sophisticated analyses using a simple graphical user interface. Among the features of this tool will be the ability to carry out Bayesian analyses using computer-aided tools that build the appropriate programs and check results for validity automatically with minimal user input. We believe completion of this tool will significantly increase the capacity of many research groups to do the types of analyses now recommended by experts.
In multivariate meta-analysis, I have a current focus in methods, applications and software for network meta-analysis, a method for synthesizing data from studies that involve different combinations of treatments or different diagnostic modalities. This method has become a key tool in comparing and ranking the effectiveness of a class of treatments and therefore of high profile in clinical research. I have been involved in the development of guidelines and reporting standards for systematic reviews and meta-analysis, including those for analyses of individual participant data, network meta-analysis and N-of-1 studies.
N-of-1 studies are single patient multiple crossover trials to compare two or more treatments. They are very patient-centered because the studies are designed by patients working with their clinicians. This enables them to choose their own outcomes, interventions and study protocols. I am working with a national research group to develop a mobile application that will enable users to enter and follow their own data. My role is to build a backend that analyzes the completed data and produce information that will help the patient and clinician to decide which treatment works best and how likely it is to be best. The analysis uses Bayesian models and automated model selection in real time.
I am working with a team that is using regression and machine learning to develop models for predicting the amount of dehydration of patients based on clinical presentation and patient-reported symptoms for children and adults presenting at a hospital in Bangladesh.
I also direct the Evidence Synthesis Academy which is developing online synchronous and asynchronous educational materials for professionals in comparative effectiveness research and meta-analysis. We aim this at those out of school who need training as well as at consumers of evidence such as the public, policy makers and the media.
I also direct the Biostatistics, Epidemiology and Study Design Key Component of the Rhode Island Center for Clinical and Translational Science, a large state-wide program to develop infrastructure in clinical research and to provide educational tools and consultative services to junior researchers. This program is a joint project of Brown University School of Public Health, the Brown Alpert Medical School, Lifespan and Care New England hospital networks, the Rhode Island Quality Institute and the University of Rhode Island. This will provide many opportunities for students to become involved with research.
Research Grants
Current
Title: Innovative Training to Improve CER PCOR Systematic Review Production and Uptake
Funding Source: Agency for Health Care Research and Quality R25 HS23299
Total Costs: $2,500,000
Funding Period: 2014-2020
Role: Principal Investigator
Title: A Mobile App for Designing and Analyzing Data from Personalized Experiments.
Funding Source: Brown Catalyst Grant Program GR300170
Total Costs: $20,000
Funding Period: 2019-2020
Role: Principal Investigator
Title: Using Single Subject (N-of-1) Designs to Answer Patient-Identified Research Questions
Funding Source: PCORI ME-16
Direct Costs: $135,000 (subcontract)
Funding Period: 2017-2020
Role: PI on subcontract (Overall PI: Heather Kaplan)
Title: RI-Center for Clinical and Translational Science
Funding Source: NIH/NIGMS 1U54GM115677
Total Costs: $19,500,000 (full)
Funding Period: 2016-2021
Role: Director of Clinical Research Design, Epidemiology, and Biostatistics Core (PI: James Padbury)
Title: Development of a novel mobile health tool for age-specific dehydration assessment and management in patients with diarrheal disease
Funding Source: NIH R01 DK116163
Total Costs: $3,300,000
Funding Period: 2018-2023
Role: Co-Investigator (PI: Adam Levine)
Title: Center for Addiction and Disease Risk Exacerbation
Funding Source: NIH P20 COBRE
Total Costs: $12,500,000
Funding Period: 2019-2024
Role: Senior Statistician (PI: Peter Monti)
Completed
Title: An MI Thrombolytic Therapy Outcome Predictive Instrument
Funding Source: Agency for Health Care Policy and Research R01 HS06208
Direct Costs: $1,227,401
Funding Period: 1989-1993
Role: Investigator/Statistician (PI: Harry Selker)
Title: Comparative Outcomes of Ambulatory Pharmaceutical Agents
Funding Source: Agency for Health Care Policy and Research R01 HS07782
Direct Costs: $1,200,000
Funding Period: 1993-1996
Role: Investigator (PI: Joseph Lau)
Title: Evaluation of the Protective Efficacy, Safety and Immunogenicity of a Recombinant DNA Expressed Protein Vaccine for Lyme Disease in Healthy Subjects
Funding Source: SmithKline Beecham Pharmaceuticals
Direct Costs: $250,000
Funding Period: 1995-1997
Role: Statistician (PI: Allen Steere)
Title: Assessing New Mathematical Models for Medical Events
Funding Source: National Library of Medicine
Direct Costs: $812,163
Funding Period: 1995-1999
Role: Investigator (PI: Harry Selker)
Title: Combining Different Data Sources to Assess Treatments
Funding Agency: Agency for Healthcare Research and Quality R01 HS08532
Direct Costs: $260,529
Funding Period: 1995-1998
Role: Principal Investigator
Title: Assessing New Mathematical Models for Medical Events
Funding Source: National Library of Medicine R01 LM05607
Direct Costs: $825,413
Funding Period: 1999-2002
Role: Investigator (PI: John Griffith)
Title: An Integrated Heuristics-Guided Meta-Analysis System
Funding Source: NCRR/Small Business Technology Transfer Program R41 RR12418
Direct Costs: $100,000
Funding Period: 1997-1998
Role: Statistician (PI: Joseph Lau)
Title: Epidemiology, Clinical Trials, and Outcomes Research
Funding Source: Nat. Institute of Diabetes and Digestive and Kidney Diseases 2T32DK007777
Direct Costs: $347,901
Funding Period: 1998-2003
Role: Faculty Member (PI: Andrew Levey)
Title: Training Evidence-Based Practitioners
Funding Source: Agency for Healthcare Research and Quality R25 HS09796
Direct Costs: $298,521
Funding Period: 1998-2001
Role: Investigator (PI: Joseph Lau)
Title: Individual Patient Meta-Analysis in Chronic Renal Disease
Funding Source: National Institute of Diabetes and Digestive and Kidney Diseases R01 DK53869
Direct Costs: $605,980
Funding Period: 1999-2002
Role: Statistician (PI: Andrew Levey)
Title: Analysis of Longitudinal Cardiopulmonary Data
Funding Source: National Institute of Heart, Lung and Blood 2R01 HL40619
Direct Costs: $164,766
Funding Period: 1991-2002
Role: Principal Investigator on NEMC subcontract (PI: Bernard Rosner)
Title: Combining Different Data Sources to Assess Treatments
Funding Agency: Agency for Healthcare Research and Quality 5 R01 HS10064
Direct Costs: $453,009
Funding Period: 1998-2002
Role: Principal Investigator
Title: Statistical Analysis of Human Circadian Rhythms
Funding Source: National Institute of General Medicine R01 GM53559
Direct Costs: $53,160
Funding Period: 2000-2003
Role: Principal Investigator on NEMC Subcontract (Overall PI: Emery Brown, MD, PhD)
Title: Combining N-of-1 Trials to Assess Fibromyalgia Therapies
Funding Source: National Institute of Arthritis and Musculoskelatal and Skin Diseases R01 AR45416
Direct Costs: $896,526
Funding Period: 1999-2003
Role: Statistician (PI: Deborah Zucker)
Title: Specialized Center of Research in Ischemia: Core C Statistical Core
Funding Source: National Institute of Heart, Lung and Blood P50 HL63494
Direct Costs: $90,470
Funding Period: 2000-2005
Role: Statistician (PI: Michael Mendelsohn)
Title: Hypertension and Renal Disease in the Pakistani Population
Funding Source: Fogarty International 5R03TW005657
Direct Costs: $32,000
Funding Period: 2002-2005
Role: Statistician (PI: Andrew Levey)
Title: Clinical Studies in Patients with Lyme Disease
Funding Source: National Institute of Arthritis and Infectious Disease N01 AI65308
Direct Costs: $ 6,720,169
Funding Period: 1996-2005
Role: Senior Statistician/ Principal Investigator (PI 1996-2001 Mark Klempner)
Title: Dealing with Publication Bias in Meta-Analysis
Funding Source: Agency for Healthcare Research and Quality R01 HS10254
Direct Costs: $388,565
Funding Period: 1999-2006
Role: Investigator (PI: Norma Terrin)
Title: Social and Affective Processes in Autism
Funding Source: NIMH/NICHD U54 MH/HD 66398
Direct Costs: $8,104,839
Funding Period: 2003-2009
Role: Statistician (PI: Helen Tager-Flusberg)
Title: Tufts-NEMC-Sackler Clinical Research Curriculum
Funding Source: National Heart Lung and Blood Institute K30 HL04116
Direct Costs: $1,000,000
Funding Period: 1999-2008
Role: Faculty Member (PI: Harry Selker)
Title: Language in Autism: Clinical and Basic Studies
Funding Source: National Institute of Mental Health 1PO1 HD34578
Direct Costs: $4,123,176
Funding Period: 1997-2007
Role: Statistician (PI: Helen Tager-Flusberg)
Title: Improving Meta-Analysis of Diagnostic Test Studies
Funding Agency: Agency for Healthcare Research and Quality 1 R01 HS13328
Direct Costs: $404,351
Funding Period: 2002-2007
Role: Principal Investigator
Title: A System for Comprehensive Meta-Analysis
Funding Agency: National Center for Research Resources 1 R33 RR17109
Direct Costs: $750,000
Funding Period: 2002-2007
Role: Principal Investigator
Title: Meta-analysis of Studies with Multiple Outcomes and Correlated Covariates
Funding Source: Pfizer Inc
Direct Costs: $100000
Funding Period: 2006-2008
Role: Statistician (PI: Joseph Lau)
Title: Chronic Renal Disease-Individual Patient Meta Analysis
Funding Source: National Institute of Diabetes and Digestive and Kidney Diseases 5 R01 DK053869
Direct Costs:$1,751,793
Funding Period: 1999-2007
Role: Statistician (PI: Andrew Levey)
Title: GPCR Variants as Genetic Determinants of Obesity
Funding Source: NIDDK/NIA/NCCAM 1R01DK072497
Direct Costs: $5,193,236
Funding Period: 2005-2009
Role: Statistician (PI: Alan Kopin)
Title: Mechanisms of Varicose Vein Formation
Funding Source: NIH/NHLBI 5R01HL081730
Direct Costs:
Funding Period: 2006-2009
Role: Statistician (PI: Mark Iafrati )
Title: Computer Program for Meta-analysis
Funding Source: AHRQ Contract #290-02-0022
Direct Costs: $94,388
Funding Period: 2008-2009
Role: Co-Investigator
Title: Relationship of Vitamin D and Calcium Intake to Nutrient Status Indicators and Health Outcomes
Funding Source: AHRQ Contract
Direct Costs: $348,879
Funding Period: 2008-2009
Role: Co-Investigator (PI: Joseph Lau)
Title: Molecular Mechanisms of Vascular Relaxation
Funding Source: National Heart, Lung and Blood Institute 1P01HL077378
Direct Costs: $11,300,000
Funding Period: 2004-2009
Role: Statistician (PI: Michael Mendelsohn)
Title: Computer Assisted Abstract Screening
Funding Source: Tufts Medical Center Research Award
Direct Costs: $50,000
Funding Period: 2009-2010
Role: Principal Investigator
Title: Clinical Research Training in Infectious Diseases
Funding Source: Nat. Institute of Allergy and Infectious Disease 1T32AI055412
Direct Costs: $1,451, 608
Funding Period: 2004-2009
Role: Statistician (PI: David Snydman)
Title: Chronic Renal Disease-Individual Patient Meta Analysis
Funding Source: National Institute of Diabetes and Digestive and Kidney Diseases U01 RDK 053869A
Direct Costs:$1,751,793
Funding Period: 2003-2010
Role: Statistician (PI: Andrew Levey)
Title: Tai Chi for Fibromyalgia
Funding Source: NIH/NCCAM R21 AT 003621
Direct Costs: $100000
Funding Period: 2007-2010
Role: Statistician (PI: Chenchen Wang)
Title: Evaluation of GFR Estimating Equations in HIV Positive Patients
Funding Source: Gilead Sciences, Inc
Direct Costs: $588,108
Funding Period: 2008-2011
Role: Statistician (PI: Lesley Stevens)
Title: Statistical Support for United States Army Research Institute of Environmental Medicine
Funding Source: US Army W911QY-06-P-0270
Direct Costs: $12,000/yr
Funding Period: 2007-2012
Role: Principal Investigator
Title: Tufts Clinical and Translational Science Institute
Funding Source: NIH/NCRR UL1 RR025752
Direct Costs:$20,000,000
Funding Period: 2008-2013
Role: Statistician (PI: Harry Selker)
Title: Postdoctoral Fellowships in Health Services Research
Funding Source: Agency for Healthcare Research and Quality T32 HS00060
Direct Costs:
Funding Period: 1993-2012
Role: Faculty Member (PI: Harry Selker)
Title: ARRA: EPC Methods Research and Resource Activities for Evidence Synthesis – Statistical Issues
Funding Source: AHRQ Contract HHSA 290-2007-10055-I Task Order No. 6
Direct Costs: $950,000
Funding Period: 2009-2012
Role: Co-Investigator (PI: Joseph Lau)
Title: Empirical Evaluation of Multivariate Meta-analysis for Binary Outcomes
Funding Source: Agency for Healthcare Research and Quality
Direct Costs: $27255
Funding Period: 2011-2013
Role: Statistical advisor (PI: Thomas Trikalinos)
Title: Empirical Evaluation of Meta-analysis of Proportions and Rates
Funding Source: Agency for Healthcare Research and Quality
Direct Costs: $15000
Funding Period: 2011-2013
Role: Statistical advisor (PI: Thomas Trikalinos)
Title: Evaluating Practices & Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test Accuracy
Funding Source: Agency for Healthcare Research and Quality
Direct Costs: $73000
Funding Period: 2011-2013
Role: Statistical advisor (PI: Thomas Trikalinos)
Title: Developing a Framework for Grading the Strength of Methodological Recommendations for Systematic Review and Meta-Analysis
Funding Source: Agency for Healthcare Research and Quality
Direct Costs: $73000
Funding Period: 2011-2013
Role: Statistical advisor (PI: Thomas Trikalinos)
Title: Kidney Function, Aortic Stiffness and Aging
Funding Source: National Institute of Diabetes and Digestive and Kidney Diseases R01 DK 082447
Direct Costs:
Funding Period: 2010-2013
Role: PI on subcontract (PI: Andrew Levey)
Title: Modernizing Meta-Analysis to Facilitate Comparative Effectiveness Reviews
Funding Source: Agency for Healthcare Research and Quality R01 HS 018574
Direct Costs: $778,325
Funding Period: 2009-2013
Role: Principal Investigator
Title: Semi-Automated Abstract Screening for Comparative Effectiveness Reviews
Funding Source: Agency for Healthcare Research and Quality R01 HS 018494
Direct Costs: $727,722
Funding Period: 2009-2013
Role: Co-Investigator (PI: Thomas Trikalinos)
Title: A Network Meta-Analysis of Pharmacological Interventions for Knee Osteoarthritis
Funding Source: Agency for Healthcare Research and Quality F32 HS 021396
Direct Costs: $100,000
Funding Period: 2012-2013
Role: Sponsor (PI: Ravi Bannuru)
Title: Standards in the Design, Conduct and Evaluation of Diagnostic Testing For Use in Patient Centered Outcomes Research
Funding Source: Patient Centered Outcomes Research Institute PCORI-SOL-RMWG-001
Direct Costs:
Funding Period: 2012
Role: Member (PI: Constantine Gatsonis)
Title: Tai Chi and Knee Osteoarthritis
Funding Source: National Center for Complementary and Alternative Medicine
Direct Costs: $381,917
Funding Period: 2010-2015
Role: Senior Statistician (PI: Chenchen Wang)
Title: Integrating Causal Inference, Evidence Synthesis, and Research Prioritization Methods
Funding Source: Patient Centered Outcomes Research Institute
Direct Costs: $700,000
Funding Period: 2013-2016
Role: Co-Investigator (PI: John Wong)
Title: Making Advanced and Accessible Statistical Tools for Quantitative Research Synthesis in Ecology and Evolutionary Biology
Funding Source: National Science Foundation
Direct Costs: $309,382
Funding Period: 2013-2016
Role: Co-Investigator (PI: Byron Wallace and Jessica Gurevitch)
Title: Tai Chi and Fibromyalgia
Funding Source: National Center for Complementary and Alternative Medicine
Direct Costs: $451,591
Funding Period: 2011-2016
Role: Senior Statistician (PI: Chenchen Wang)
Title: Evidence Based Practice Center IV
Funding Source: Agency for Healthcare Research and Quality
Direct Costs: $70000
Funding Period: 2012-2015
Role: Statistical advisor (PI: Thomas Trikalinos)
Title: Evaluating Observational Data Analyses: Confounding Control and Treatment Effect Heterogeneity
Funding Source: Patient Centered Outcomes Research Institute
Direct Costs: $700,000
Funding Period: 2014-2016
Role: Co-Investigator (PI: Issa Dahabreh)
Title: Making better use of randomized trials: assessing applicability & transporting causal effects
Funding Source: PCORI ME-1502-27794
Direct Costs: $750,000
Funding Period: 2015-2016
Role: Co-Investigator (PI: Issa Dahabreh)
Title: Methods and Dissemination: Collaboration to improve validity, consistency, and utility of systematic reviews
Funding Source: Agency for Healthcare Research and Quality
Direct Costs: $47,385
Funding Period: 2013-2017
Role: Co-Investigator (PI: Thomas Trikalinos)
Title: Emulators for facilitating the development, analysis, and use of complex decision models with an application in prostate cancer
Funding Source: AHRQ R36 HS2465301
Direct Costs: $40,000
Funding Period: 2016-2017
Role: Mentor (PI: Alexandra Ellis)
Title: Postdoctoral Fellowships in Health Services Research
Funding Source: Agency for Healthcare Research and Quality
Direct Costs:
Funding Period: 2013-2017
Role: Faculty Member (PI: Vince Mor)
Title: Center of Excellence in Physical Therapy
Funding Source: Foundation for Physical Therapy
Direct Costs: $2,286,921
Funding Period: 2013-2017
Role: Co-Investigator (PI: Linda Resnik)
Title: N-of-1 Trials Using mHealth in Chronic Pain
Funding Source: National Institute of Nursing Research R01 NR13938
Direct Costs: $290,273 (subcontract)
Funding Period: 2012-2018
Role: PI on subcontract (Overall PI: Richard Kravitz)
Title: Develop, Test and Disseminate a New Technology to Modernize Data Abstraction in PCOR Systematic Reviews
Funding Source: PCORI
Direct Costs: $184,899 (subcontract)
Funding Period: 2014-2018
Role: PI on subcontract (Overall PI: Tianjing Li)
Title: Develop Patient Centered Outcomes Scholars for Comparative Effectiveness Research
Funding Source: AHRQ 1K12 HS022998
Total Costs: $1,200,000
Funding Period: 2014-2019
Role: Co-Investigator (PI: Thomas Trikalinos)
Courses/Workshops/Webinars
National
International
Invited Presentations
National
International
Other Presentations
National
International
| Year | Degree | Institution |
|---|---|---|
| 1991 | PhD | Harvard University |
1988-1991 National Research Service Award, National Institute of Health
2000 Drug Information Association Donald E. Francke Award (best paper of year)
2006 Elected member, Society for Research Synthesis Methodology
2010 Fellow, American Statistical Association
2010 Dean's Outstanding Sackler Faculty Mentor Award, Tufts Medical School
2010 Tufts University School of Medicine Distinguished Faculty Award
| Name | Title |
|---|---|
| Aston, Elizabeth | Associate Professor of Behavioral and Social Sciences (Research) |
| Chen, Elizabeth | Interim Director of the Center for Biomedical Informatics, Associate Professor of Medical Science, Associate Professor of Health Services, Policy and Practice |
| Dahabreh, Issa | Adjunct Associate Professor of Epidemiology |
| Gareen, Ilana | Associate Professor of Epidemiology (Research) |
| Gatsonis, Constantine | Henry Ledyard Goddard University Professor of Statistical Sciences, Director of the Center for Statistical Sciences |
| Gutman, Roee | Professor of Biostatistics |
| Jay, Gregory | John and Mary Panton and Emergency Medicine Professor of Translational Science, Professor of Orthopaedics, Professor of Medicine, Professor of Engineering (Research) |
| Machan, Jason | Associate Professor of Surgery (Research), Associate Professor of Orthopaedics (Research) |
| Monti, Peter | Donald G. Millar Distinguished Professor of Alcohol and Addiction Studies, Professor of Behavioral and Social Sciences |
| Mor, Vincent | Florence Pirce Grant University Professor of Health Services, Policy and Practice, Professor of Health Services, Policy and Practice |
| Padbury, James | William and Mary Oh - William and Elsa Zopfi Professor of Pediatrics for Perinatal Research |
| Rounds, Sharon | Associate Dean for Translational Science, Professor of Medicine, Professor of Pathology and Laboratory Medicine |
| Saldanha, Ian | Adjunct Associate Professor of Health Services, Policy and Practice |
| Sarkar, Neil | Associate Professor of Medical Science, Associate Professor of Health Services, Policy and Practice |
| Sullivan, Adam | Assistant Professor of the Practice of Biostatistics |
| Trikalinos, Thomas | Professor of Health Services, Policy and Practice, Director of the Center for Evidence Synthesis in Health |
| Wilson, Ira | Associate Provost for Academic Space, Professor of Health Services, Policy and Practice, Professor of Medicine |
Biostatistics
Meta-analysis/Systematic review
Predictive Models
Statistical Learning
Clinical Trials
| DATA 2020 - Probability, Statistics, and Machine Learning: Advanced Methods |
| PHP 0100 - First year seminar: Statistics is everywhere |
| PHP 1510 - Principles of Biostatistics and Data Analysis |
| PHP 2514 - Applied Generalized Linear Models |
| PHP 2550 - Practical Data Analysis |
| PHP 2590 - Design of Experiments |
| PHP 2690H - Design of Experiments |
