Gregory D. JayProfessor of Emergency Medicine, Professor of Medicine, Professor of Engineering (Research)
GREGORY D. JAY, MD, PhD, is Professor of Emergency Medicine and Engineering at Brown University in the Department of Emergency Medicine and Division of Engineering, and an attending physician at Rhode Island Hospital. In October 2004 Dr. Jay was selected as recipient of the Bruce M. Selya Award for Research Excellence.
Smith-Bindman, Rebecca, Aubin, Chandra, Bailitz, John, Bengiamin, Rimon N., Camargo, Carlos A., Corbo, Jill, Dean, Anthony J., Goldstein, Ruth B., Griffey, Richard T., Jay, Gregory D., Kang, Tarina L., Kriesel, Dana R., Ma, O. John, Mallin, Michael, Manson, William, Melnikow, Joy, Miglioretti, Diana L., Miller, Sara K., Mills, Lisa D., Miner, James R., Moghadassi, Michelle, Noble, Vicki E., Press, Gregory M., Stoller, Marshall L., Valencia, Victoria E., Wang, Jessica, Wang, Ralph C., Cummings, Steven R.
Ultrasonography versus Computed Tomography for Suspected Nephrolithiasis
New England Journal of Medicine.
. full textPubMed
Elsaid, KA, Jay, GD, Chichester, CO: Detection of collagen type II and proteoglycans in the synovial fluids of patients diagnosed with non-Infectious knee joint synovitis indicates early damage to the articular cartilage matrix. Osteoarthritis & Cartilage 11:673-680, 2003
Morey, J, Simon, R, Jay, GD, Wears, RL, Salisbury, M, Berns, SD and the MedTeams Research Consortium: Error reduction and performance improvement in the Emergency Department through teamwork training: Validation results of the MedTeams Project. Health Services Research 37(6):1553-1581, 2002.
Jay, GD, Harris, DA, Cha, CJ: Boundary lubrication by lubricin is mediated by O-linked b(1-3)Gal-GalNAc oligosaccharides. Glycoconjugate Journal 18, 807-815, 2002.
Dr. Jay has investigated the lubricating properties of synovial fluid and what role it may play in degenerative joint diseases. He confirmed that lubricin is a mucinous glycoprotein and showed that the glycosylations on this molecule provide for a lower coefficient of friction between both biological and non-biological rubbing surfaces. He is interested in more immediate translational studies in the areas of automated pulsus paradoxus monitoring in emergency medicine. He has developed and/or tested a portable hyperbaric chamber system, bedside co-oximetry, and other novel devices.
Dr. Gregory D. Jay, Associate Professor, received his M.D., Ph.D. from the Medical Scientist Training Program at the State University of New York at Stony Brook in 1990. He completed training in emergency medicine at the University of Massachusetts from 1990 through 1993 and became a fellow of the American College of Emergency Physicians in 1996. Dr. Jay also served in the Air National Guard during 1986 through 1998 serving as a flight surgeon in the 106th Aerospace Rescue & Recovery Group and the 143rd Tactical Airlift Group. Dr. Jay is an Associate Professor of Emergency Medicine, Medicine and Engineering, and is an Adjunct Professor in Biomedical Sciences at the University of Rhode Island. He has published over 50 peer-reviewed publications, and has 13 U.S. and international patents. Dr. Jay serves as Director of Research in the Department of Emergency Medicine at Brown University. He has been the principal investigator or co-investigator on multiple National Institutes of Health (NIH) and National Science Foundation (NSF) grants supporting his research on mammalian joint lubrication and how this system prevents degenerative joint disease. He has also developed and investigated the clinical utility of automated pulsus paradoxus monitoring in emergency medicine. Dr. Jay has also worked constructively with industry in helping develop portable hyperbaric systems, bedside co-oximetry, and other novel devices.
"Isolation of Lubricin from Human Synovial Fibroblasts and Development of Immunological Probes". Principal Investigator; $19,630 awarded by Rhode Island Hospital; 12/1/1995-11/30/1996.
"Medical Error Reduction: Emergency Medical Team Performance (MedTeams®) Phase I & II". Co-Principal Investigator; $855,533 awarded by Army Research LaboratoryContract #DAAL01-96-C-0091, Aberdeen Proving Grounds subcontracted through Dynamics Research Corporation, Wilmington, MA; 9/1/1996-2/29/2000.
"Medical Error Reduction: Emergency Medical Team Performance (MedTeams®) Phase III. Development of the Emergency Team Coordination Course Supported by High Fidelity Simulation Training to Improve Team Performance (ETCC-S)". Co-Principal Investigator; $154,152 awarded by Army Research LaboratoryContract #DAAL01-96-C-0091, Aberdeen Proving Grounds subcontracted through Dynamics Research Corporation, Wilmington, MA; 3/1/2000-3/1/2001.
"Immunoprobes for Human Lubricin from Human Synovial Fluid". Mentored Clinical Scientist Development Award; National Institutes of Health, National Institute on Aging, 1K08AG/AR01008-01; Principal Investigator; $386,553 awarded 8/1/2000-8/1/2004. Mentor: Douglas Hixson, Ph.D.
"Study of Biological Boundary Lubrication using Atomic Force Microscopy in the Pulsed Force Mode". McCutchen Foundation; Principal Investigator; $34,700 awarded 1/1/2001-1/1/2002.
"Design and Construction of a High Fidelity Medical Simulation Suite at Rhode Island Hospital". Champlin Foundation; Co-Principal Investigator; $100,000 awarded 12/1/2000-12/1/2001.
"Developmental Center for Evaluation and Research in Patient Safety (DCERPS)". Agency for Healthcare Research and Quality, P20HF11592; Co-Investigator, Principal InvestigatorDr. Robert Wears, University of Florida, Co-Principal InvestigatorDr. Marc Shapiro, Brown University School of Medicine; $100,135 awarded 9/01/2001-8/31/2004.
"Pneumothorax Detection System (PDS)". National Institutes of Health, National Heart, Lung and Blood Institute, R44 HL66126, Phase IISmall Business Innovation Research Award, Co-Investigator; Principal InvestigatorDr. Ronald G. Riechers, Spectra Research Inc.; $208,437 awarded 9/1/2002-8/31/2004.
"Lubricin in Articulating Joints". National Institutes of Health, National Institute of Arthritis, Musculoskeletal and Skin Diseases, RO1 AR050180-01; Co-Investigator with Matthew Warman, M.D. at Case Western Reserve University; $2,159,560 awarded 7/1/2003-8/31/2008.
"Acquisition of a Nanoindentation System for Multi-disciplinary Research and Education in Nano and Bio-mechanics of Materials". National Science Foundation, CMS-0421199; Co-Principal Investigator with P.R. Guduru, B.W. Sheldon, R.F. Cooper and K-S. Kim; $249,515 awarded 7/15/2004-6/30/2005.
"Pulsus Paradoxus Monitor". National Institutes of Health, National Institute of Heart, Lung and Blood, R41 HL74633-01; Principal Investigator; Small Business Technology Transfer Award to Plethlogic Inc.; $298,776 awarded 9/1/2004-8/31/2006.
"Non-invasive Device to Measure Hemoglobin Levels: Improving the Quality of Life of Persons with Life Altering Diseases". Culpeper Foundation; Co-Principal Investigator with G. Crawford; $25,000 awarded 10/1/2004-9/30/2006.
"GlobaMED Devices: Global Anemia Detection & Treatment". NCIIA Advanced E-Team Grant #3289-06. Co- Investigator and Mentor. John McCurdy (recipient). $20,000.
"Lubricin in ACL Deficient Joints". Centers of Biomedical Research Excellence (COBRE) NCRR, 1P20RR024484-01. Investigator. $1,147,751 awarded 9/1/07 – 8/31/12. Department of Orthopaedics at Brown Medical School. Qian Chen PhD (Program Project PI).
"Restitution of Lubrication in ACL Deficient Joints Preventing Wear". NIAMS, R21AR055937. Principal Investigator. $365,234 awarded 5/1/08 – 4/30/10.
"Creating a Reliable, Fast and Affordable Way to Diagnose Anemia". Rhode Island Science & Technology Advisory Council Award. Co-Principal Investigator. $180,000 awarded 2/1/08 – 6/1/09.
"Lubricin in Articulating Joints. National Institutes of Health". National Institute of Arthritis, Musculoskeletal and Skin Diseases, RO1 AR050180-01. Co-Principal Investigator with Matthew Warman MD at Boston Children’s Hospital. $2,459,560 awarded 9/1/08 - 8/31/13
"Tribosupplementation of Injured Joints". National Institutes of Health National Institute of Arthritis and Musculoskeletal and Skin Diseases, 1R41AR057276-01. Principal Investigator. $284,758 awarded 09/30/2009 – 08/31/2011.
"RCT of US versus CT for Patients in the ED with Suspected Renal Colic (STONE)". AHRQ R01 HS019312. Co-Investigator with Rebecca Bindman at University of California at San Francisco. $601,552 awarded 9/30/2010 – 9/29/2013.
"Improving Pediatric Resuscitation: A Simulation Program for the Community ED". AHRQ R18 HS20286. Co-Investigator with Linda Brown at Rhode Island Hospital. $937,978 awarded 2/1/2011 – 1/31/2014.
"Tribosupplementation with Lubricin in Prevention of Post-Traumatic Arthritis". Department of Defense, Congressionally Directed Medical Research Program, PR110746, Co-Principal Investigator with Braden Fleming at Brown University. $2,219,221 awarded 10/1/2012 – 9/30/2015.
"Tribosupplementation of Injured Joints". National Institutes of Health National Institute of Arthritis and Musculoskeletal and Skin Diseases, 1R42AR057276-03. Principal Investigator. $1,075,259 awarded 9/1/13 – 8/31/15.