Associate Professor of Engineering, Director of Biomedical Engineering


Dr. Coulombe specializes in cardiovascular regenerative engineering to address global needs to develop novel therapies for heart attack and technologies for cardiotoxicity assessment.  A major focus of her research is to re-engineer contractility in the heart after myocardial infarction (heart attack) using engineered human myocardium with cardiomyocytes derived from human induced pluripotent stem cells.  Complex biology underlies the engineering of heart tissue so that it has electromechanical function for predicting toxicity or integrating with the heart electrically and via neovasculature.  Dr. Coulombe earned a B.S. in Biomedical Engineering at the University of Rochester summa cum laude in 2001 and was a Whitaker Predoctoral Fellow, earning a Ph.D. in Bioengineering at the University of Washington in 2007. She was an NIH Ruth L. Kirschstein post-doctoral fellow in Pathology at the University of Washington where she won an NIH Pathway to Independence K99/R00 award in 2012.  She was recruited to Brown in January 2014 and is now an Associate Professor of Engineering in the Instute for Biology, Engineering and Medicine.

Brown Affiliations

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