Biographical Sketch 2024
W. Curt LaFrance, Jr., MD, MPH, FAAN, FANPA, DFAPA, FAES, is Professor of Psychiatry and Neurology at Alpert Medical School, Brown University and Inaugural Director of Neuropsychiatry and Behavioral Neurology at Rhode Island Hospital (RIH). He is Director of the VA Mind Brain Program, Program Director for the VA National Expert Consultation and Specialized Services Neuropsychiatry Clinic and Staff Physician at the VA Providence Health Care System. In his clinical and forensic neuropsychiaty practice, he sees referrals from around the country with neuropsychiatric disorders, including traumatic brain injury, seizure, movement, cognitive, mood, anxiety disorders, along with patients with conversion / functional neurological / somatic symptom disorders.
Dr. LaFrance studied at Wake Forest University (BA in psychology), Medical College of Georgia (MD) and Brown University (MPH). He came to Brown in 1995 for his internship in internal medicine and completed the combined residency in neurology and psychiatry at Brown, and he is boarded in both neurology and in psychiatry by the American Board of Psychiatry and Neurology. After residency, he completed a Clinical Research Fellowship in Combined Treatments at Brown University with an institutional NIH T-32 National Research Service Award. He is the recipient of awards, recognitions and grants, including the American Neuropsychiatric Association’s (ANPA) Career Development Award, the American Academy of Neurology’s (AAN) Dreifuss-Penry Epilepsy Award, and Marquis’ Who’s Who in the World. He has served on the Epilepsy Foundation (EF) Professional Advisory Board, chaired American Epilepsy Society (AES) and International League Against Epilepsy (ILAE) Task Forces, as a steward for the AES/NINDS Epilepsy Benchmarks, and on the Governor’s Permanent Advisory Commission on Traumatic Brain Injury. He was an Advisor to the DSM 5 Workgroup on Somatoform Disorders. He served on the Council for the ANPA, and he is a founding member and on the Board of Directors of the Functional Neurological Disorder Society.
Dr. LaFrance has received grants from the EF, AES, Siravo Foundation, the VA and DoD, and an NINDS K23 Award. He directed the combined residency at Brown from 2012-2019 and has served as research advisor or mentor to psychiatry, neurology and neuropsychiatry residents and faculty and to Brown undergraduates in neurobiology and psychology. He trains clinicians around the country in Neuro-Behavioral Therapy, using distance supervision, for treatment delivery for seizures and somatoform disorders. He has given over 270 invited lectures around the country and world. His research interests focus on developing new biomarkers and treatments for neuropsychiatric aspects of epilepsy, conversion (functional) / somatoform disorders and TBI. His studies are published in peer reviewed neurology and psychiatry journals, with over 160 publications. He serves on journal editorial boards for Epilepsy and Behavior, Journal of Neuropsychiatry and Clinical Neurosciences, and the Journal of Neurology, Neurosurgery and Psychiatry. He is co-editor of the 4th edition of Nonepileptic Seizures and co-author of Taking Control of Your Seizures: Workbook and Therapist Guide.
A goal of his work at Brown, nationally and internationally has been to bridge neurology and psychiatry clinical practice and scientific research and to dissolve arbitrary boundaries between the two fields.
| Allendorfer JB, Nenert R, Goodman AM, Kakulamarri P, Correia S, Philip NS, LaFrance WC Jr, Szaflarski JP. "Brain network entropy, depression, and quality of life in people with traumatic brain injury and seizure disorders." Epilepsia open, vol. 9, no. 3, 2024, pp. 969-980. |
| Byington CG, Goodman AM, Allendorfer JB, Correia S, LaFrance WC Jr, Szaflarski JP. "Decreased uncinate fasciculus integrity in functional seizures following traumatic brain injury." Epilepsia, vol. 65, no. 4, 2024, pp. 1060-1071. |
| Roghani A, Wang CP, Henion A, Amuan M, Altalib H, LaFrance WC Jr, Baca C, Van Cott A, Towne A, Kean J, Hinds SR, Kennedy E, Panahi S, Pugh MJ. "Mortality among veterans with epilepsy: Temporal significance of traumatic brain injury exposure." Epilepsia, vol. 65, no. 8, 2024, pp. 2255-2269. |
| Van Patten R, Blum A, Correia S, Philip NS, Allendorfer JB, Gaston TE, Goodman A, Grayson LP, Tocco K, Vogel V, Martin A, Fry S, Bolding M, Ver Hoef L, Baird GL, Szaflarski JP, LaFrance WC Jr. "One-year follow-up of neurobehavioral therapy in functional seizures or epilepsy with traumatic brain injury: A nonrandomized controlled trial." Epilepsia, 2024. |
| Van Patten R, Chan L, Tocco K, Mordecai K, Altalib H, Cotton E, Correia S, Gaston TE, Grayson LP, Martin A, Fry S, Goodman A, Allendorfer JB, Szaflarski J, LaFrance WC Jr. "Reduced Subjective Cognitive Concerns With Neurobehavioral Therapy in Functional Seizures and Traumatic Brain Injury." The Journal of neuropsychiatry and clinical neurosciences, 2024, pp. appineuropsych20230138. |
| Perez DL, Nicholson TR, Asadi-Pooya AA, Butler M, Carson AJ, David AS, Deeley Q, Diez I, Edwards MJ, Espay AJ, Gelauff JM, Jungilligens J, Hallett M, Kanaan RAA, Tijssen MAJ, Kozlowska K, LaFrance WC Jr, Marapin RS, Maurer CW, Reinders AATS, Sojka P, Staab JP, Stone J, Szaflarski JP, Aybek S. "Response to the Letter Concerning the Publication: Neuroimaging in Functional Neurological Disorder: State of the Field and Research Agenda. Perez DL et al. Neuroimage Clin. 2021;30:102623." NeuroImage. Clinical, vol. 41, 2024, pp. 103573. |
| Lopez MR, Mordecai K, Blanken AE, LaFrance WC Jr. "Caring for Patients With Functional Neurological Disorder-A New Paradigm." Cognitive and Behavioral Neurology, 2023. |
| LaFrance WC Jr, Tedesco R, Baird GL, Wincze J, Tocco K, Anderson J. "Clinician-rated outcomes of patients with functional neurological disorders treated in an outpatient clinic." Seizure, vol. 107, 2023, pp. 21-27. |
| Van Patten R, Chan L, Tocco K, Mordecai K, Altalib H, Twamley EW, Gaston TE, Grayson LP, Martin A, Fry S, Goodman A, Allendorfer JB, Correia S, Szaflarski J, LaFrance WC Jr. "Improvements in Montreal Cognitive Assessment scores after neurobehavioral therapy in adults with functional (nonepileptic) seizures and traumatic brain injury." Journal of Psychiatric Research, vol. 165, 2023, pp. 282-289. |
| Gandy M, Michaelis R, Acraman J, Donald KA, Fitzpatrick M, LaFrance WC Jr, Margolis SA, Modi AC, Reuber M, Tang V, Thayer Z, Verity K, Wagner JL, Wilmshurst J, Whittaker S, Munger Clary HM. "Integrated psychological care services within seizure settings: Key components and implementation factors among example services in four ILAE regions: A report by the ILAE Psychiatry Commission." Epilepsia, vol. 64, no. 7, 2023, pp. 1766-1784. |
| Mueller C, Goodman AM, Nenert R, Allendorfer JB, Philip NS, Correia S, Oster RA, LaFrance WC Jr, Szaflarski JP. "Repeatability of neurite orientation dispersion and density imaging in patients with traumatic brain injury." Journal of Neuroimaging, vol. 33, no. 5, 2023, pp. 802-824. |
| Henion AK, Wang CP, Amuan M, Altalib HH, Towne AR, Hinds SR, Baca C, LaFrance WC Jr, Van Cott AC, Kean J, Roghani A, Kennedy E, Panahi S, Pugh MJV. "Role of Deployment History on the Association Between Epilepsy and Traumatic Brain Injury in Post-9/11 Era US Veterans." Neurology, vol. 101, no. 24, 2023, pp. e2571-e2584. |
| Mueller C, Goodman AM, Allendorfer JB, Nenert R, Gaston TE, Grayson LE, Correia S, Philip NS, LaFrance WC Jr, Szaflarski JP. "White Matter Changes after Neurobehavioral Therapy for Functional Seizures." Annals of neurology, vol. 94, no. 2, 2023, pp. 350-365. |
| Szaflarski JP, Allendorfer JB, Goodman AM, Byington CG, Philip NS, Correia S, LaFrance WC Jr. "Diagnostic delay in functional seizures is associated with abnormal processing of facial emotions." Epilepsy & Behavior, vol. 131, no. Pt A, 2022, pp. 108712. |
| Beimer NJ, LaFrance WC Jr. "Evaluation and Treatment of Psychogenic Nonepileptic Seizures." Neurologic clinics, vol. 40, no. 4, 2022, pp. 799-820. |
| Ertan D, Aybek S, LaFrance WC Jr, Kanemoto K, Tarrada A, Maillard L, El-Hage W, Hingray C. "Functional (psychogenic non-epileptic/dissociative) seizures: why and how?." Journal of Neurology, Neurosurgery & Psychiatry, vol. 93, no. 2, 2022, pp. 144-157. |
| LaFrance WC Jr. "LaFrance memories of Schachter letter, E&B special issue honoring Steve Schachter." Epilepsy & Behavior, vol. 137, no. Pt B, 2022, pp. 108843. |
| Goodman AM, Allendorfer JB, LaFrance WC Jr, Szaflarski JP. "Precentral gyrus and insula responses to stress vary with duration to diagnosis in functional seizures." Epilepsia, vol. 63, no. 4, 2022, pp. 865-879. |
| DeGrush E, LaFrance WC Jr. "Psychotherapeutic Tools to Enhance the Neurologist-Patient Interaction." Seminars in Neurology, vol. 42, no. 2, 2022, pp. 107-113. |
| Escoffery C, Haardoerfer R, Bamps Y, McGee R, Geiger D, Quarells RC, Thompson NJ, Patel A, Anderson M, LaFrance WC Jr. "Reduction of the Adult Epilepsy Self-Management Measure Instrument (AESMMI)." Epilepsy & Behavior, vol. 131, no. Pt A, 2022, pp. 108692. |
| Sharma AA, Goodman AM, Allendorfer JB, Philip NS, Correia S, LaFrance WC Jr, Szaflarski JP. "Regional brain atrophy and aberrant cortical folding relate to anxiety and depression in patients with traumatic brain injury and psychogenic nonepileptic seizures." Epilepsia, vol. 63, no. 1, 2022, pp. 222-236. |
| Goodman AM, Kakulamarri P, Nenert R, Allendorfer JB, Philip NS, Correia S, LaFrance WC Jr, Szaflarski JP. "Relationship between intrinsic network connectivity and psychiatric symptom severity in functional seizures." Journal of Neurology, Neurosurgery & Psychiatry, vol. 94, no. 2, 2022, pp. 136-143. |
| Lopez MR, LaFrance WC. "Treatment of Psychogenic Nonepileptic Seizures." Current Neurology and Neuroscience Reports, vol. 22, no. 8, 2022, pp. 467-474. |
| Michaelis R, Tang V, Nevitt SJ, Wagner JL, Modi AC, LaFrance WC Jr, Goldstein LH, Gandy M, Bresnahan R, Valente K, Donald KA, Reuber M. "Cochrane systematic review and meta-analysis of the impact of psychological treatment on health-related quality of life in people with epilepsy: an update by the ILAE Psychology Task Force, highlighting methodological changes." Epileptic disorders : international epilepsy journal with videotape, vol. 23, no. 6, 2021, pp. 803-811. |
| Perez DL, Edwards MJ, Nielsen G, Kozlowska K, Hallett M, LaFrance WC Jr. "Decade of progress in motor functional neurological disorder: continuing the momentum." Journal of Neurology, Neurosurgery & Psychiatry, 2021. |
| Wardrope A, Dworetzky BA, Barkley GL, Baslet G, Buchhalter J, Doss J, Goldstein LH, Hallett M, Kozlowska K, LaFrance WC Jr, McGonigal A, Mildon B, Oto M, Perez DL, Riker E, Roberts NA, Stone J, Tolchin B, Reuber M. "How to do things with words: Two seminars on the naming of functional (psychogenic, non-epileptic, dissociative, conversion, …) seizures." Seizure, vol. 93, 2021, pp. 102-110. |
| Gandy M, Modi AC, Wagner JL, LaFrance WC Jr, Reuber M, Tang V, Valente KD, Goldstein LH, Donald KA, Rayner G, Michaelis R. "Managing depression and anxiety in people with epilepsy: A survey of epilepsy health professionals by the ILAE Psychology Task Force." Epilepsia open, vol. 6, no. 1, 2021, pp. 127-139. |
| Perez DL, Nicholson TR, Asadi-Pooya AA, Bègue I, Butler M, Carson AJ, David AS, Deeley Q, Diez I, Edwards MJ, Espay AJ, Gelauff JM, Hallett M, Horovitz SG, Jungilligens J, Kanaan RAA, Tijssen MAJ, Kozlowska K, LaFaver K, LaFrance WC Jr, Lidstone SC, Marapin RS, Maurer CW, Modirrousta M, Reinders AATS, Sojka P, Staab JP, Stone J, Szaflarski JP, Aybek S. "Neuroimaging in Functional Neurological Disorder: State of the Field and Research Agenda." NeuroImage. Clinical, vol. 30, 2021, pp. 102623. |
| Milligan TA, Yun A, LaFrance WC Jr, Baslet G, Tolchin B, Szaflarski J, Wong VSS, Plioplys S, Dworetzky BA. "Neurology residents' education in functional seizures." Epilepsy & behavior reports, vol. 18, 2021, pp. 100517. |
| Onorati F, Regalia G, Caborni C, LaFrance WC Jr, Blum AS, Bidwell J, De Liso P, El Atrache R, Loddenkemper T, Mohammadpour-Touserkani F, Sarkis RA, Friedman D, Jeschke J, Picard R. "Prospective Study of a Multimodal Convulsive Seizure Detection Wearable System on Pediatric and Adult Patients in the Epilepsy Monitoring Unit." Frontiers in Neurology, vol. 12, 2021, pp. 724904. |
| Bègue I, Nicholson TR, Kozlowska K, LaFrance WC, Levenson JL, Rapaport MH, Carson AJ, Perez DL. "Psychiatry's modern role in functional neurological disorder: join the renaissance." Psychological Medicine, 2021, pp. 1-3. |
| Paola L, LaFrance WC Jr. "Psychogenic Nonepileptic Seizures (PNES) classification: still "time for progress"." Arquivos de Neuro-Psiquiatria, vol. 79, no. 4, 2021, pp. 269-271. |
| Balachandran N, Goodman AM, Allendorfer JB, Martin AN, Tocco K, Vogel V, LaFrance WC Jr, Szaflarski JP. "Relationship between neural responses to stress and mental health symptoms in psychogenic nonepileptic seizures after traumatic brain injury." Epilepsia, vol. 62, no. 1, 2021, pp. 107-119. |
| Tolchin B, Baslet G, Carson A, Dworetzky BA, Goldstein LH, LaFrance WC Jr, Martino S, Perez DL, Reuber M, Stone J, Szaflarski JP. "The role of evidence-based guidelines in the diagnosis and treatment of functional neurological disorder." Epilepsy & behavior reports, vol. 16, 2021, pp. 100494. |
| Gras A, Wardrope A, Hirsch E, Asadi Pooya AA, Duncan R, Gigineishvili D, Hingray C, Kanemoto K, Ladino L, LaFrance WC, McGonigal A, Pretorius C, Valenti Hirsch P, Vidailhet P, Zhou D, Reuber M. "Use of suggestive seizure manipulation methods in the investigation of patients with possible psychogenic nonepileptic seizures-An international ILAE survey." Epilepsia open, 2021. |
| Tatum WO, Hirsch LJ, Gelfand MA, Acton EK, LaFrance WC, Duckrow RB, Chen D, Blum AS, Hixson J, Drazkowski J, Benbadis S, Cascino GD, OSmartViE Collaborators. "Video quality using outpatient smartphone videos in epilepsy: Results from the OSmartViE study." European journal of neurology, 2021. |
| Perez DL, Aybek S, Popkirov S, Kozlowska K, Stephen CD, Anderson J, Shura R, Ducharme S, Carson A, Hallett M, Nicholson TR, Stone J, LaFrance WC Jr, Voon V, (On behalf of the American Neuropsychiatric Association Committee for Research. "A Review and Expert Opinion on the Neuropsychiatric Assessment of Motor Functional Neurological Disorders." The Journal of neuropsychiatry and clinical neurosciences, 2020, pp. appineuropsych19120357. |
| Tatum WO, Hirsch LJ, Gelfand MA, Acton EK, LaFrance WC Jr, Duckrow RB, Chen DK, Blum AS, Hixson JD, Drazkowski JF, Benbadis SR, Cascino GD, OSmartViE Investigators. "Assessment of the Predictive Value of Outpatient Smartphone Videos for Diagnosis of Epileptic Seizures." JAMA neurology, vol. 77, no. 5, 2020, pp. 593-600. |
| Asadi-Pooya AA, Nicholson TR, Pick S, Baslet G, Benbadis SR, Beghi M, Brigo F, Buchhalter J, D'Alessio L, Dworetzky B, Gigineishvili D, Kanaan RA, Kozlowska K, LaFrance WC Jr, Lehn A, Perez DL, Popkirov S, Pretorius C, Szaflarski JP, Tolchin B, Valente K, Stone J, Reuber M. "Driving a motor vehicle and psychogenic nonepileptic seizures: ILAE Report by the Task Force on Psychogenic Nonepileptic Seizures." Epilepsia open, vol. 5, no. 3, 2020, pp. 371-385. |
| Baslet G, Bajestan SN, Aybek S, Modirrousta M, D Clin Psy JP, Cavanna A, Perez DL, Lazarow SS, Raynor G, Voon V, Ducharme S, LaFrance WC Jr. "Evidence-Based Practice for the Clinical Assessment of Psychogenic Nonepileptic Seizures: A Report From the American Neuropsychiatric Association Committee on Research." The Journal of neuropsychiatry and clinical neurosciences, 2020, pp. appineuropsych19120354. |
| LaFrance WC Jr, Ho WLN, Bhatla A, Baird G, Altalib HH, Godleski L. "Examination of Potential Differences in Reporting of Sensitive Psychosocial Measures via Diagnostic Evaluation Using Computer Video Telehealth." The Journal of neuropsychiatry and clinical neurosciences, vol. 32, no. 3, 2020, pp. appineuropsych19080177. |
| Perez DL, Aybek S, Nicholson TR, Kozlowska K, Arciniegas DB, LaFrance WC Jr. "Functional Neurological (Conversion) Disorder: A Core Neuropsychiatric Disorder." The Journal of neuropsychiatry and clinical neurosciences, vol. 32, no. 1, 2020, pp. 1-3. |
| Leibetseder A, Eisermann M, LaFrance WC Jr, Nobili L, von Oertzen TJ. "How to distinguish seizures from non-epileptic manifestations." Epileptic disorders : international epilepsy journal with videotape, vol. 22, no. 6, 2020, pp. 716-738. |
| Cheng Y, Pereira M, Raukar NP, Reagan JL, Quesenberry M, Goldberg L, Borgovan T, LaFrance Jr WC, Dooner M, Deregibus M, Camussi G, Ramratnam B, Quesenberry P. "Inflammation-related gene expression profiles of salivary extracellular vesicles in patients with head trauma." Neural regeneration research, vol. 15, no. 4, 2020, pp. 676-681. |
| LaFrance WC Jr, Vo P, Baird G, East R, Stein NR. "Moral injury in Veterans with nonepileptic seizures." Epilepsy & Behavior, vol. 102, 2020, pp. 106681. |
| Bruzzone Giraldez MJ, LaFrance WC Jr. "Mortality in patients with psychogenic nonepileptic seizures: A wake-up call." Neurology, vol. 95, no. 6, 2020, pp. 237-238. |
| Tolchin B, Hirsch LJ, LaFrance WC Jr. "Neuropsychiatric Aspects of Epilepsy." Psychiatric Clinics of North America, vol. 43, no. 2, 2020, pp. 275-290. |
| Pick S, Anderson DG, Asadi-Pooya AA, Aybek S, Baslet G, Bloem BR, Bradley-Westguard A, Brown RJ, Carson AJ, Chalder T, Damianova M, David AS, Edwards MJ, Epstein SA, Espay AJ, Garcin B, Goldstein LH, Hallett M, Jankovic J, Joyce EM, Kanaan RA, Keynejad RC, Kozlowska K, LaFaver K, LaFrance WC Jr, Lang AE, Lehn A, Lidstone S, Maurer CW, Mildon B, Morgante F, Myers L, Nicholson C, Nielsen G, Perez DL, Popkirov S, Reuber M, Rommelfanger KS, Schwingenshuh P, Serranova T, Shotbolt P, Stebbins GT, Stone J, Tijssen MA, Tinazzi M, Nicholson TR. "Outcome measurement in functional neurological disorder: a systematic review and recommendations." Journal of Neurology, Neurosurgery & Psychiatry, vol. 91, no. 6, 2020, pp. 638-649. |
| Michaelis R, Tang V, Nevitt SJ, Wagner JL, Modi AC, LaFrance WC Jr, Goldstein LH, Gandy M, Bresnahan R, Valente K, Donald KA, Reuber M. "Psychological treatments for people with epilepsy." The Cochrane database of systematic reviews, vol. 8, 2020, pp. CD012081. |
| Ranford J, MacLean J, Alluri PR, Comeau O, Godena E, LaFrance WC Jr, Hunt A, Stephen CD, Perez DL. "Sensory Processing Difficulties in Functional Neurological Disorder: A Possible Predisposing Vulnerability?." Psychosomatics, vol. 61, no. 4, 2020, pp. 343-352. |
| LaFaver K, LaFrance WC, Price ME, Rosen PB, Rapaport M. "Treatment of functional neurological disorder: current state, future directions, and a research agenda." CNS Spectrums, 2020, pp. 1-7. |
| LaFrance WC Jr, Ho WLN, Bhatla A, Baird GL, Altalib HH, Godleski L. "Treatment of psychogenic nonepileptic seizures (PNES) using video telehealth." Epilepsia, vol. 61, no. 11, 2020, pp. 2572-2582. |
| Goodman AM, Allendorfer JB, Blum AS, Bolding MS, Correia S, Ver Hoef LW, Gaston TE, Grayson LE, Kraguljac NV, Lahti AC, Martin AN, Monroe WS, Philip NS, Tocco K, Vogel V, LaFrance WC Jr, Szaflarski JP. "White matter and neurite morphology differ in psychogenic nonepileptic seizures." Annals of Clinical and Translational Neurology, vol. 7, no. 10, 2020, pp. 1973-1984. |
| Kobau R, Manderscheid R, Owens S, LaFrance WC Jr, Sajatovic M. "Bridging the divide between epilepsy and mental health to drive solutions." Epilepsy & Behavior, vol. 101, no. Pt A, 2019, pp. 106576. |
| Espay AJ, Ries S, Maloney T, Vannest J, Neefus E, Dwivedi AK, Allendorfer JB, Wulsin LR, LaFrance WC, Lang AE, Szaflarski JP. "Clinical and neural responses to cognitive behavioral therapy for functional tremor." Neurology, vol. 93, no. 19, 2019, pp. e1787-e1798. |
| Diez I, Ortiz-Terán L, Williams B, Jalilianhasanpour R, Ospina JP, Dickerson BC, Keshavan MS, LaFrance WC Jr, Sepulcre J, Perez DL. "Corticolimbic fast-tracking: enhanced multimodal integration in functional neurological disorder." Journal of Neurology, Neurosurgery & Psychiatry, vol. 90, no. 8, 2019, pp. 929-938. |
| Zsom A, Tsekhan S, Hamid T, Levin J, Truccolo W, LaFrance WC, Blum AS, Li P, Wahed LA, Shaikh MA, Sharma G, Ranieri R, Zhang L. "Ictal autonomic activity recorded via wearable-sensors plus machine learning can discriminate epileptic and psychogenic nonepileptic seizures." 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, vol. 2019, 2019, pp. 3502-3506. |
| Beghi M, Cornaggia CM, Beghi E, LaFrance WC Jr. "Is drug treatment of psychogenic nonepileptic seizures effective?." Epilepsy & Behavior, vol. 98, no. Pt A, 2019, pp. 288-289. |
| Syed TU, LaFrance WC Jr, Loddenkemper T, Benbadis S, Slater JD, El-Atrache R, AlBunni H, Khan MT, Aziz S, Ali NY, Khan FA, Alnobani A, Hussain FM, Syed AU, Koubeissi MZ. "Outcome of ambulatory video-EEG monitoring in a ˜10,000 patient nationwide cohort." Seizure, vol. 66, 2019, pp. 104-111. |
| Cheng Y, Pereira M, Raukar N, Reagan JL, Queseneberry M, Goldberg L, Borgovan T, LaFrance WC Jr, Dooner M, Deregibus M, Camussi G, Ramratnam B, Quesenberry P. "Potential biomarkers to detect traumatic brain injury by the profiling of salivary extracellular vesicles." Journal of cellular physiology, vol. 234, no. 8, 2019, pp. 14377-14388. |
| Popkirov S, Asadi-Pooya AA, Duncan R, Gigineishvili D, Hingray C, Miguel Kanner A, LaFrance WC Jr, Pretorius C, Reuber M. "The aetiology of psychogenic non-epileptic seizures: risk factors and comorbidities." Epileptic disorders : international epilepsy journal with videotape, vol. 21, no. 6, 2019, pp. 529-547. |
| Cretton A, Brown RJ, LaFrance WC Jr, Aybek S. "What Does Neuroscience Tell Us About the Conversion Model of Functional Neurological Disorders?." The Journal of neuropsychiatry and clinical neurosciences, 2019, pp. appineuropsych19040089. |
| Hingray C, El-Hage W, Duncan R, Gigineishvili D, Kanemoto K, LaFrance WC Jr, de Marinis A, Paul R, Pretorius C, Téllez-Zenteno JF, Wiseman H, Reuber M. "Access to diagnostic and therapeutic facilities for psychogenic nonepileptic seizures: An international survey by the ILAE PNES Task Force." Epilepsia, vol. 59, no. 1, 2018, pp. 203-214. |
| Perez DL, Williams B, Matin N, Mello J, Dickerson BC, LaFrance WC Jr, Keshavan MS. "Anterior hippocampal grey matter predicts mental health outcome in functional neurological disorders: an exploratory pilot study." Journal of Neurology, Neurosurgery & Psychiatry, 2018. |
| Michaelis R, Tang V, Wagner JL, Modi AC, LaFrance WC Jr, Goldstein LH, Lundgren T, Reuber M. "Cochrane systematic review and meta-analysis of the impact of psychological treatments for people with epilepsy on health-related quality of life." Epilepsia, vol. 59, no. 2, 2018, pp. 315-332. |
| Perez DL, Matin N, Williams B, Tanev K, Makris N, LaFrance WC Jr, Dickerson BC. "Cortical thickness alterations linked to somatoform and psychological dissociation in functional neurological disorders." Human Brain Mapping, vol. 39, no. 1, 2018, pp. 428-439. |
| Espay AJ, Aybek S, Carson A, Edwards MJ, Goldstein LH, Hallett M, LaFaver K, LaFrance WC Jr, Lang AE, Nicholson T, Nielsen G, Reuber M, Voon V, Stone J, Morgante F. "Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders." JAMA neurology, 2018. |
| Szaflarski JP, Allendorfer JB, Nenert R, LaFrance WC Jr, Barkan HI, DeWolfe J, Pati S, Thomas AE, Ver Hoef L. "Facial emotion processing in patients with seizure disorders." Epilepsy & Behavior, vol. 79, 2018, pp. 193-204. |
| Williams B, Jalilianhasanpour R, Matin N, Fricchione GL, Sepulcre J, Keshavan MS, LaFrance WC Jr, Dickerson BC, Perez DL. "Individual differences in corticolimbic structural profiles linked to insecure attachment and coping styles in motor functional neurological disorders." Journal of Psychiatric Research, vol. 102, 2018, pp. 230-237. |
| Glass SP, Matin N, Williams B, Mello J, Stephen CD, Young SS, Callahan J, LaFrance WC Jr, Perez DL. "Neuropsychiatric Factors Linked to Adherence and Short-Term Outcome in a U.S. Functional Neurological Disorders Clinic: A Retrospective Cohort Study." The Journal of neuropsychiatry and clinical neurosciences, vol. 30, no. 2, 2018, pp. 152-159. |
| Spader HS, Dean DC 3rd, LaFrance WC Jr, Raukar NP, Cosgrove GR, Eyerly-Webb SA, Ellermeier A, Correia S, Deoni SCL, Rogg J. "Prospective study of myelin water fraction changes after mild traumatic brain injury in collegiate contact sports." Journal of Neurosurgery, 2018, pp. 1-9. |
| Szaflarski JP, LaFrance WC Jr. "Psychogenic Nonepileptic Seizures (PNES) as a Network Disorder - Evidence From Neuroimaging of Functional (Psychogenic) Neurological Disorders." Epilepsy currents / American Epilepsy Society, vol. 18, no. 4, 2018, pp. 211-216. |
| Michaelis R, Tang V, Goldstein LH, Reuber M, LaFrance WC Jr, Lundgren T, Modi AC, Wagner JL. "Psychological treatments for adults and children with epilepsy: Evidence-based recommendations by the International League Against Epilepsy Psychology Task Force." Epilepsia, vol. 59, no. 7, 2018, pp. 1282-1302. |
| Jalilianhasanpour R, Williams B, Gilman I, Burke MJ, Glass S, Fricchione GL, Keshavan MS, LaFrance WC Jr, Perez DL. "Resilience linked to personality dimensions, alexithymia and affective symptoms in motor functional neurological disorders." Journal of Psychosomatic Research, vol. 107, 2018, pp. 55-61. |
| Jalilianhasanpour R, Ospina JP, Williams B, Mello J, MacLean J, Ranford J, Fricchione GL, LaFrance WC Jr, Perez DL. "Secure Attachment and Depression Predict 6-Month Outcome in Motor Functional Neurological Disorders: A Prospective Pilot Study." Psychosomatics, 2018. |
| Bursch B, Forgey M, Emerson ND, Siddarth P, Weisbrot DM, Shaw RJ, Doss J, Falcone T, Hinman K, LaFrance WC Jr, Laptook R, Willis MD, Deggelman EL, Caplan R, Plioplys S. "Sibling-Controlled Study of Parental Bonding, Coping, and Urgent Health-Care Use in Families With Children With Nonepileptic Seizures." J. Pediatr. Psychol., vol. 43, no. 10, 2018, pp. 1128-1137. |
| Adams C, Anderson J, Madva EN, LaFrance WC Jr, Perez DL. "You've made the diagnosis of functional neurological disorder: now what?." Practical neurology, 2018. |
| Perez DL, Matin N, Barsky A, Costumero-Ramos V, Makaretz SJ, Young SS, Sepulcre J, LaFrance WC Jr, Keshavan MS, Dickerson BC. "Cingulo-insular structural alterations associated with psychogenic symptoms, childhood abuse and PTSD in functional neurological disorders." Journal of Neurology, Neurosurgery & Psychiatry, vol. 88, no. 6, 2017, pp. 491-497. |
| Baird, Grayson L., Harlow, Lisa L., Machan, Jason T., Curt LaFrance, W. "Cluster reduction in patients in a pilot treatment trial for psychogenic nonepileptic seizures." Epilepsy & Behavior, vol. 73, 2017, pp. 273-279. |
| Perez DL, Williams B, Matin N, LaFrance WC Jr, Costumero-Ramos V, Fricchione GL, Sepulcre J, Keshavan MS, Dickerson BC. "Corticolimbic structural alterations linked to health status and trait anxiety in functional neurological disorder." Journal of Neurology, Neurosurgery & Psychiatry, 2017. |
| Galioto R, Tremont G, Blum AS, LaFrance WC Jr, Crook CL, Davis JD. "Depressive Symptoms Contribute to Executive Deficits in Temporal Lobe Epilepsy." The Journal of Neuropsychiatry and Clinical Neurosciences, vol. 29, no. 2, 2017, pp. 135-141. |
| Baird GL, Harlow LL, Machan JT, Thomas D, LaFrance WC Jr. "Identifying seizure clusters in patients with psychogenic nonepileptic seizures." Epilepsy & Behavior, vol. 73, 2017, pp. 142-147. |
| Onorati F, Regalia G, Caborni C, Migliorini M, Bender D, Poh MZ, Frazier C, Kovitch Thropp E, Mynatt ED, Bidwell J, Mai R, LaFrance WC Jr, Blum AS, Friedman D, Loddenkemper T, Mohammadpour-Touserkani F, Reinsberger C, Tognetti S, Picard RW. "Multicenter clinical assessment of improved wearable multimodal convulsive seizure detectors." Epilepsia, 2017. |
| Matin N, Young SS, Williams B, LaFrance WC Jr, King JN, Caplan D, Chemali Z, Weilburg JB, Dickerson BC, Perez DL. "Neuropsychiatric Associations With Gender, Illness Duration, Work Disability, and Motor Subtype in a U.S. Functional Neurological Disorders Clinic Population." The Journal of neuropsychiatry and clinical neurosciences, 2017, pp. appineuropsych16110302. |
| Lafrance WC Jr, Ranieri R, Blum AS. "Nonepileptic seizures - objective phenomena." Handbook of clinical neurology, vol. 139, 2017, pp. 297-304. |
| Ekanayake, Vindhya, Kranick, Sarah, LaFaver, Kathrin, Naz, Arshi, Frank Webb, Anne, LaFrance, W. Curt, Hallett, Mark, Voon, Valerie. "Personality traits in psychogenic nonepileptic seizures (PNES) and psychogenic movement disorder (PMD): Neuroticism and perfectionism." Journal of Psychosomatic Research, vol. 97, 2017, pp. 23-29. |
| Kanemoto K, LaFrance WC Jr, Duncan R, Gigineishvili D, Park SP, Tadokoro Y, Ikeda H, Paul R, Zhou D, Taniguchi G, Kerr M, Oshima T, Jin K, Reuber M. "PNES around the world: Where we are now and how we can close the diagnosis and treatment gaps-an ILAE PNES Task Force report." Epilepsia open, vol. 2, no. 3, 2017, pp. 307-316. |
| Chen DK, Sharma E, LaFrance WC Jr. "Psychogenic Non-Epileptic Seizures." Current Neurology and Neuroscience Reports, vol. 17, no. 9, 2017, pp. 71. |
| Michaelis R, Tang V, Wagner JL, Modi AC, LaFrance WC Jr, Goldstein LH, Lundgren T, Reuber M. "Psychological treatments for people with epilepsy." The Cochrane database of systematic reviews, vol. 10, 2017, pp. CD012081. |
| Doss J, Caplan R, Siddarth P, Bursch B, Falcone T, Forgey M, Hinman K, LaFrance WC Jr, Laptook R, Shaw R, Weisbrot D, Willis M, Plioplys S. "Risk factors for learning problems in youth with psychogenic non-epileptic seizures." Epilepsy & Behavior, vol. 70, no. Pt A, 2017, pp. 135-139. |
| Valente KD, De Paola L, Palmini A, Faveret E, de Araujo-Filho GM, van der Linden H, Bianchin MM, Walz R, Alessi R, Velasco T, Teixeira WA, LaFrance WC Jr. "The approach to patients with psychogenic nonepileptic seizures in epilepsy surgery centers regarding diagnosis, treatment, and education." Epilepsy & Behavior, vol. 68, 2017, pp. 78-83. |
| Kavanaugh B, Correia S, Jones J, Blum A, LaFrance WC Jr, Davis JD. "White matter integrity correlates with depressive symptomatology in temporal lobe epilepsy." Epilepsy & Behavior, vol. 77, 2017, pp. 99-105. |
| Goldman AM, LaFrance WC Jr, Benke T, Asato M, Drane D, Pack A, Syed T, Doss R, Lhatoo S, Fureman B, Dingledine R, American Epilepsy Society (AES)/National Institute of Neurological Disorders and Stroke (NINDS) Epilepsy Benchmark Stewards. "2014 Epilepsy Benchmarks Area IV: Limit or Prevent Adverse Consequence of Seizures and Their Treatment Across The Lifespan." Epilepsy currents / American Epilepsy Society, vol. 16, no. 3, 2016, pp. 198-205. |
| Bajestan SN, LaFrance WC Jr. "Clinical Approaches to Psychogenic Nonepileptic Seizures." FOC, vol. 14, no. 4, 2016, pp. 422-431. |
| Miller LA, Galioto R, Tremont G, Davis J, Bryant K, Roth J, LaFrance WC Jr, Blum AS. "Cognitive impairment in older adults with epilepsy: Characterization and risk factor analysis." Epilepsy & Behavior, vol. 56, 2016, pp. 113-117. |
| Altalib HH, Elzamzamy K, Pugh MJ, Gonzalez JB, Cheung KH, Fenton BT, Kerns RD, Brandt CA, LaFrance WC Jr. "Communicating diagnostic certainty of psychogenic nonepileptic seizures - a national study of provider documentation." Epilepsy & Behavior, vol. 64, no. Pt A, 2016, pp. 4-8. |
| Chen DK, LaFrance WC Jr. "Diagnosis and Treatment of Nonepileptic Seizures." Continuum (Minneapolis, Minn.), vol. 22, no. 1 Epilepsy, 2016, pp. 116-31. |
| Voon V, Cavanna AE, Coburn K, Sampson S, Reeve A, LaFrance WC Jr, (On behalf of the American Neuropsychiatric Association Committee for Research). "Functional Neuroanatomy and Neurophysiology of Functional Neurological Disorders (Conversion Disorder)." The Journal of neuropsychiatry and clinical neurosciences, 2016, pp. appineuropsych14090217. |
| Perez DL, LaFrance WC. "Nonepileptic seizures: an updated review." CNS Spectrums, 2016, pp. 1-8. |
| VA Epilepsy Centers of Excellence., Altalib H, Cavazos J, Pugh MJ, Hussain A, Kelly-Foxworth P, Tran T, Krumholz A, LaFrance WC, Lopez MR, Rutecki P, Van Cott A. "Providing Quality Epilepsy Care for Veterans." Federal practitioner : for the health care professionals of the VA, DoD, and PHS, vol. 33, no. 9, 2016, pp. 26-32. |
| Doss RC, LaFrance WC Jr. "Psychogenic non-epileptic seizures." Epileptic disorders : international epilepsy journal with videotape, vol. 18, no. 4, 2016, pp. 337-343. |
| Plioplys S, Doss J, Siddarth P, Bursch B, Falcone T, Forgey M, Hinman K, LaFrance WC Jr, Laptook R, Shaw RJ, Weisbrot DM, Willis MD, Caplan R. "Risk factors for comorbid psychopathology in youth with psychogenic nonepileptic seizures." Seizure, vol. 38, 2016, pp. 32-7. |
| Wissel BD, Dwivedi AK, Gaston TE, Rodriguez-Porcel FJ, Aljaafari D, Hopp JL, Krumholz A, van der Salm SMA, Andrade DM, Borlot F, Moseley BD, Cavitt JL, Williams S, Stone J, LaFrance WC Jr, Szaflarski JP, Espay AJ. "Which patients with epilepsy are at risk for psychogenic nonepileptic seizures (PNES)? A multicenter case-control study." Epilepsy & Behavior, vol. 61, 2016, pp. 180-184. |
| LaFrance, W. Curt, Ranieri, Rebecca, Bamps, Yvan, Stoll, Shelley, Sahoo, Satya S., Welter, Elisabeth, Sams, Johnny, Tatsuoka, Curtis, Sajatovic, Martha. "Comparison of common data elements from the Managing Epilepsy Well (MEW) Network integrated database and a well-characterized sample with nonepileptic seizures." Epilepsy & Behavior, vol. 45, 2015, pp. 136-141. |
| Escoffery C, Bamps Y, LaFrance WC Jr, Stoll S, Shegog R, Buelow J, Shafer P, Thompson NJ, McGee RE, Hatfield K. "Development of the Adult Epilepsy Self-Management Measurement Instrument (AESMMI)." Epilepsy & Behavior, vol. 50, 2015, pp. 172-83. |
| Escoffery C, Bamps Y, LaFrance WC Jr, Stoll S, Shegog R, Buelow J, Shafer P, Thompson NJ, McGee RE, Hatfield K. "Factor analyses of an Adult Epilepsy Self-Management Measurement Instrument (AESMMI)." Epilepsy & Behavior, vol. 50, 2015, pp. 184-9. |
| Egan RA, LaFrance WC Jr. "Functional Vision Disorder." Seminars in Neurology, vol. 35, no. 5, 2015, pp. 557-63. |
| De Paola L, Terra VC, Silvado CE, Teive HA, Palmini A, Valente KD, Olandoski M, LaFrance WC Jr. "Improving first responders' psychogenic nonepileptic seizures diagnosis accuracy: Development and validation of a 6-item bedside diagnostic tool." Epilepsy & Behavior, vol. 54, 2015, pp. 40-46. |
| Valente KD, Rzezak P, LaFrance WC Jr. "Standard medical care for psychogenic nonepileptic seizures in Brazil." Epilepsy & Behavior, vol. 45, 2015, pp. 128-35. |
| LaFrance WC Jr. "'Hysteria' today and tomorrow." Frontiers of neurology and neuroscience, vol. 35, 2014, pp. 198-204. |
| Plioplys, Sigita, Doss, Julia, Siddarth, Prabha, Bursch, Brenda, Falcone, Tatiana, Forgey, Marcy, Hinman, Kyle, LaFrance, W. Curt, Laptook, Rebecca, Shaw, Richard J., Weisbrot, Deborah M., Willis, Matthew D., Caplan, Rochelle. "A multisite controlled study of risk factors in pediatric psychogenic nonepileptic seizures." Epilepsia, vol. 55, no. 11, 2014, pp. 1739-1747. |
| LaFrance WC Jr, Ranieri R. "Comments on Reuber et al. Psychogenic nonepileptic seizures: review and update. Epilepsy & behavior 2003;4:205-216." Epilepsy & Behavior, vol. 40, 2014, pp. 13-5. |
| Kanner, Andres M., Schachter, Steven C., Barry, John J., Hesdorffer, Dale C., Mula, Marco, Trimble, Michael, Hermann, Bruce, Ettinger, Alan E., Dunn, David, Caplan, Rochelle, Ryvlin, Philippe, Gilliam, Frank, LaFrance, W. Curt. "Corrigendum to “Depression and epilepsy, pain and psychogenic nonepileptic seizures: Clinical and therapeutic perspectives” [Epilepsy Behav 24/2 (2012) 169–181]." Epilepsy & Behavior, vol. 32, 2014, pp. 171. |
| Kanner, Andres M., Schachter, Steven C., Barry, John J., Hesdorffer, Dale C., Mula, Marco, Trimble, Michael, Hermann, Bruce, Ettinger, Alan E., Dunn, David, Caplan, Rochelle, Ryvlin, Philippe, Gilliam, Frank, LaFrance, W. Curt. "Corrigendum to “Depression and epilepsy: Epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrence” [Epilepsy Behav 24/2 (2012) 156–168]." Epilepsy & Behavior, vol. 32, 2014, pp. 170. |
| LaFrance WC Jr, Duncan R, Reuber M, Goldstein LH, Baker GA. "In response to comments on Parietal seizures mimicking psychogenic nonepileptic seizures." Epilepsia, vol. 55, no. 1, 2014, pp. 197-8. |
| Fertig E, Fureman BE, Bergey GK, Brodie MA, Hesdorffer DC, Hirtz D, Kossoff EH, LaFrance WC Jr, Versavel M, French J. "Inclusion and exclusion criteria for epilepsy clinical trials-recommendations from the April 30, 2011 NINDS workshop." Epilepsy Research, vol. 108, no. 5, 2014, pp. 825-32. |
| LaFrance, W. Curt, Baird, Grayson L., Barry, John J., Blum, Andrew S., Frank Webb, Anne, Keitner, Gabor I., Machan, Jason T., Miller, Ivan, Szaflarski, Jerzy P. "Multicenter Pilot Treatment Trial for Psychogenic Nonepileptic Seizures." JAMA Psychiatry, vol. 71, no. 9, 2014, pp. 997-1005. |
| McMillan KK, Pugh MJ, Hamid H, Salinsky M, Pugh J, Noël PH, Finley EP, Leykum LK, Lanham HJ, LaFrance WC Jr. "Providers' perspectives on treating psychogenic nonepileptic seizures: Frustration and hope." Epilepsy & Behavior, vol. 37C, 2014, pp. 276-281. |
| Paola LD, Marchetti RL, Teive HA, LaFrance WC Jr. "Psychogenic nonepileptic seizures and psychogenic movement disorders: two sides of the same coin?." Arquivos de Neuro-Psiquiatria, vol. 72, no. 10, 2014, pp. 793-802. |
| Rogg J, Spader H, Wilcox BJ, Ellermeier A, Correira S, Chodobski A, Szmydynger-Chodobska J, Raukar N, Machan JT, Crisco JJ, LaFrance WC Jr, Brown University Traumatic Brain Injury Research Consortium. "The Brown University Traumatic Brain Injury Research Consortium and the Norman Prince Neurosciences Institute." Rhode Island medical journal (2013), vol. 97, no. 5, 2014, pp. 22-6. |
| LaFrance WC Jr. "The influence and impact of Epilepsy & Behavior on the neuropsychiatric aspects of seizures." Epilepsy & Behavior, vol. 40, 2014, pp. 73. |
| LaFrance WC Jr, Reuber M, Goldstein LH. "Management of psychogenic nonepileptic seizures." Epilepsia, vol. 54 Suppl 1, 2013, pp. 53-67. |
| LaFrance WC Jr, Baker GA, Duncan R, Goldstein LH, Reuber M. "Minimum requirements for the diagnosis of psychogenic nonepileptic seizures: a staged approach: a report from the International League Against Epilepsy Nonepileptic Seizures Task Force." Epilepsia, vol. 54, no. 11, 2013, pp. 2005-18. |
| LaFrance WC Jr, Deluca M, Machan JT, Fava JL. "Traumatic brain injury and psychogenic nonepileptic seizures yield worse outcomes." Epilepsia, vol. 54, no. 4, 2013, pp. 718-25. |
| Hamid H, Fodeh SJ, Lizama AG, Czlapinski R, Pugh MJ, LaFrance WC Jr, Brandt CA. "Validating a natural language processing tool to exclude psychogenic nonepileptic seizures in electronic medical record-based epilepsy research." Epilepsy & Behavior, vol. 29, no. 3, 2013, pp. 578-80. |
| Hopp JL, LaFrance WC Jr. "Cognitive behavioral therapy for psychogenic neurological disorders." The neurologist, vol. 18, no. 6, 2012, pp. 364-72. |
| LaFrance WC Jr, de Marinis AJ, Webb AF, Machan JT, Rusch MD, Kanner AM. "Comparing standard medical care for nonepileptic seizures in Chile and the United States." Epilepsy & Behavior, vol. 25, no. 2, 2012, pp. 224-9. |
| Tremont G, Smith MM, Bauer L, Alosco ML, Davis JD, Blum AS, LaFrance WC Jr. "Comparison of personality characteristics on the bear-fedio inventory between patients with epilepsy and those with non-epileptic seizures." The Journal of neuropsychiatry and clinical neurosciences, vol. 24, no. 1, 2012, pp. 47-52. |
| Kanner AM, Schachter SC, Barry JJ, Hesdorffer DC, Mula M, Trimble M, Hermann B, Ettinger AE, Dunn D, Caplan R, Ryvlin P, Gilliam F, LaFrance WC Jr. "Depression and epilepsy, pain and psychogenic non-epileptic seizures: clinical and therapeutic perspectives." Epilepsy & Behavior, vol. 24, no. 2, 2012, pp. 169-81. |
| Kanner AM, Schachter SC, Barry JJ, Hesdorffer DC, Mula M, Trimble M, Hermann B, Ettinger AE, Dunn D, Caplan R, Ryvlin P, Gilliam F, LaFrance WC Jr. "Depression and epilepsy: epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrence." Epilepsy & Behavior, vol. 24, no. 2, 2012, pp. 156-68. |
| LaFrance WC Jr, Lancman G, Machan JT, Davis JD, Blum AS. "Depression symptoms as a function of duration of intractable or controlled epilepsy." Epilepsy & Behavior, vol. 24, no. 1, 2012, pp. 116-9. |
| LaFrance WC Jr, Plioplys S. "Neuropsychiatric disorders: does semiology of psychogenic nonepileptic seizures matter?." Nature reviews. Neurology, vol. 8, no. 6, 2012, pp. 302-3. |
| Syed TU, LaFrance WC Jr, Kahriman ES, Hasan SN, Rajasekaran V, Gulati D, Borad S, Shahid A, Fernandez-Baca G, Garcia N, Pawlowski M, Loddenkemper T, Amina S, Koubeissi MZ. "Can semiology predict psychogenic nonepileptic seizures? A prospective study." Annals of neurology, vol. 69, no. 6, 2011, pp. 997-1004. |
| Stone J, LaFrance WC Jr, Brown R, Spiegel D, Levenson JL, Sharpe M. "Conversion disorder: current problems and potential solutions for DSM-5." Journal of Psychosomatic Research, vol. 71, no. 6, 2011, pp. 369-76. |
| Zhang, H.-L., Bianchin, M. M., Bragatti, J. A., Torres, C. M., Nuernberg, G. L., Rieder, C. R., LaFrance, W. C., Leaver, K., Papadonatos, G. D., Stopa, E. G., Blum, A. S. "Decreased serum BDNF levels in patients with epileptic and psychogenic nonepileptic seizures." Neurology, vol. 76, no. 20, 2011, pp. 1772-1772. |
| Devinsky O, Gazzola D, LaFrance WC Jr. "Differentiating between nonepileptic and epileptic seizures." Nature reviews. Neurology, vol. 7, no. 4, 2011, pp. 210-20. |
| LaFrance WC Jr, Benbadis SR. "Differentiating frontal lobe epilepsy from psychogenic nonepileptic seizures." Neurologic clinics, vol. 29, no. 1, 2011, pp. 149-62, ix. |
| LaFrance WC Jr, Alosco ML, Davis JD, Tremont G, Ryan CE, Keitner GI, Miller IW, Blum AS. "Impact of family functioning on quality of life in patients with psychogenic nonepileptic seizures versus epilepsy." Epilepsia, vol. 52, no. 2, 2011, pp. 292-300. |
| Kerr MP, Mensah S, Besag F, de Toffol B, Ettinger A, Kanemoto K, Kanner A, Kemp S, Krishnamoorthy E, LaFrance WC Jr, Mula M, Schmitz B, van Elst LT, Trollor J, Wilson SJ, International League of Epilepsy (ILAE) Commission on the Neuropsychiatric Aspects of Epilepsy. "International consensus clinical practice statements for the treatment of neuropsychiatric conditions associated with epilepsy." Epilepsia, vol. 52, no. 11, 2011, pp. 2133-8. |
| Patel H, Dunn DW, Austin JK, Doss JL, LaFrance WC Jr, Plioplys S, Caplan R. "Psychogenic nonepileptic seizures (pseudoseizures)." Pediatrics in Review, vol. 32, no. 6, 2011, pp. e66-72. |
| Brown RJ, Syed TU, Benbadis S, LaFrance WC Jr, Reuber M. "Psychogenic nonepileptic seizures." Epilepsy & Behavior, vol. 22, no. 1, 2011, pp. 85-93. |
| LaFrance, W. Curt, Friedman, Joseph H. "Cognitive behavioral therapy for psychogenic movement disorder." Mov. Disord., vol. 25, no. 13, 2010, pp. 2268-2268. |
| LaFrance WC Jr, Leaver K, Stopa EG, Papandonatos GD, Blum AS. "Decreased serum BDNF levels in patients with epileptic and psychogenic nonepileptic seizures." Neurology, vol. 75, no. 14, 2010, pp. 1285-91. |
| Voon V, Brezing C, Gallea C, Ameli R, Roelofs K, LaFrance WC Jr, Hallett M. "Emotional stimuli and motor conversion disorder." Brain, vol. 133, no. Pt 5, 2010, pp. 1526-36. |
| Stone J, LaFrance WC Jr, Levenson JL, Sharpe M. "Issues for DSM-5: Conversion disorder." American Journal of Psychiatry, vol. 167, no. 6, 2010, pp. 626-7. |
| Salpekar JA, Plioplys S, Siddarth P, Bursch B, Shaw RJ, Asato MR, LaFrance WC Jr, Weisbrot DM, Dunn DW, Austin JK, Olson DM, Caplan R. "Pediatric psychogenic nonepileptic seizures: a study of assessment tools." Epilepsy & Behavior, vol. 17, no. 1, 2010, pp. 50-5. |
| LaFrance WC Jr, Keitner GI, Papandonatos GD, Blum AS, Machan JT, Ryan CE, Miller IW. "Pilot pharmacologic randomized controlled trial for psychogenic nonepileptic seizures." Neurology, vol. 75, no. 13, 2010, pp. 1166-73. |
| Friedman JH, LaFrance WC Jr. "Psychogenic disorders: the need to speak plainly." Archives of Neurology, vol. 67, no. 6, 2010, pp. 753-5. |
| Karam, C., Sethi, N. K., Sethi, P., Torgovnick, J., Arsura, E., Cowan, R. B. T., Ramos, V. F. M. L., Ramos, M. L., Ramos, H. M., Landau, W. M., Benbadis, S., LaFrance, W. C. "Psychogenic nonepileptic "seizures " or "attacks"? It's not just semantics: Attacks: Psychogenic nonepileptic "seizures" or "attacks"? It's not just semantics: Seizures." Neurology, vol. 75, no. 23, 2010, pp. 2135-2137. |
| LaFrance WC Jr. "Psychogenic nonepileptic "seizures" or "attacks"? It's not just semantics: seizures." Neurology, vol. 75, no. 1, 2010, pp. 87-8. |
| LaFrance WC Jr, Friedman JH. "Cognitive behavioral therapy for psychogenic movement disorder." Mov. Disord., vol. 24, no. 12, 2009, pp. 1856-7. |
| LaFrance WC Jr, Miller IW, Ryan CE, Blum AS, Solomon DA, Kelley JE, Keitner GI. "Cognitive behavioral therapy for psychogenic nonepileptic seizures." Epilepsy & Behavior, vol. 14, no. 4, 2009, pp. 591-6. |
| LaFrance WC Jr, Syc S. "Depression and symptoms affect quality of life in psychogenic nonepileptic seizures." Neurology, vol. 73, no. 5, 2009, pp. 366-71. |
| Benbadis SR, LaFrance WC Jr, Papandonatos GD, Korabathina K, Lin K, Kraemer HC, NES Treatment Workshop. "Interrater reliability of EEG-video monitoring." Neurology, vol. 73, no. 11, 2009, pp. 843-6. |
| Nicholl J, LaFrance WC Jr. "Neuropsychiatric sequelae of traumatic brain injury." Seminars in Neurology, vol. 29, no. 3, 2009, pp. 247-55. |
| LaFrance WC Jr. "Somatoform disorders." Seminars in Neurology, vol. 29, no. 3, 2009, pp. 234-46. |
| LaFrance WC Jr, Self JA. "Do bus accidents cause nonepileptic seizures?: complex issues of medicolegal causation." The journal of the American Academy of Psychiatry and the Law, vol. 36, no. 2, 2008, pp. 227-33. |
| LaFrance WC Jr, Kanner AM, Hermann B. "Psychiatric comorbidities in epilepsy." International review of neurobiology, vol. 83, 2008, pp. 347-83. |
| LaFrance WC Jr. "Psychogenic nonepileptic seizures." Current opinion in neurology, vol. 21, no. 2, 2008, pp. 195-201. |
| LaFrance WC Jr, Gates JR, Trimble MR. "Psychogenic unresponsiveness and nonepileptic seizures." Handbook of clinical neurology, vol. 90, 2008, pp. 317-28. |
| LaFrance WC Jr. "Video NeuroImage: diagnosing conversion weakness with the Spinal Injuries Center test: when Hoover doesn't help." Neurology, vol. 71, no. 19, 2008, pp. e57. |
| LaFrance WC Jr, Rusch MD, Machan JT. "What is "treatment as usual" for nonepileptic seizures?." Epilepsy & Behavior, vol. 12, no. 3, 2008, pp. 388-94. |
| LaFrance, W. Curt, Blum, Andrew S., Miller, Ivan W., Ryan, Christine E., Keitner, Gabor I. "Methodological Issues in Conducting Treatment Trials for Psychological Nonepileptic Seizures." The Journal of neuropsychiatry and clinical neurosciences, vol. 19, no. 4, 2007, pp. 391-398. |
| LaFrance WC Jr, Blum AS, Miller IW, Ryan CE, Keitner GI. "Methodological issues in conducting treatment trials for psychological nonepileptic seizures." The Journal of neuropsychiatry and clinical neurosciences, vol. 19, no. 4, 2007, pp. 391-8. |
| LaFrance WC Jr. "Treating patients with functional symptoms: one size does not fit all." Journal of Psychosomatic Research, vol. 63, no. 6, 2007, pp. 633-5. |
| LaFrance WC Jr, Benbadis SR. "Avoiding the costs of unrecognized psychological nonepileptic seizures." Neurology, vol. 66, no. 11, 2006, pp. 1620-1. |
| LaFrance WC Jr, Alper K, Babcock D, Barry JJ, Benbadis S, Caplan R, Gates J, Jacobs M, Kanner A, Martin R, Rundhaugen L, Stewart R, Vert C, NES Treatment Workshop participants. "Nonepileptic seizures treatment workshop summary." Epilepsy & Behavior, vol. 8, no. 3, 2006, pp. 451-61. |
| LaFrance WC Jr. "Use of serum prolactin in diagnosing epileptic seizures: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology." Neurology, vol. 66, no. 8, 2006, pp. 1287-8; author reply 1287-8. |
| LaFrance WC Jr, Barry JJ. "Update on treatments of psychological nonepileptic seizures." Epilepsy & Behavior, vol. 7, no. 3, 2005, pp. 364-74. |
| LaFrance WC Jr, Devinsky O. "The treatment of nonepileptic seizures: historical perspectives and future directions." Epilepsia, vol. 45 Suppl 2, 2004, pp. 15-21. |
| Royall DR, Lauterbach EC, Cummings JL, Reeve A, Rummans TA, Kaufer DI, LaFrance WC Jr, Coffey CE. "Executive control function: a review of its promise and challenges for clinical research. A report from the Committee on Research of the American Neuropsychiatric Association." The Journal of neuropsychiatry and clinical neurosciences, vol. 14, no. 4, 2002, pp. 377-405. |
| LaFrance WC. "How many patients with psychogenic nonepileptic seizures also have epilepsy?." Neurology, vol. 58, no. 6, 2002, pp. 990; author reply 990-1. |
| LaFrance WC Jr, Devinsky O. "Treatment of nonepileptic seizures." Epilepsy & Behavior, vol. 3, no. 5 Suppl, 2002, pp. 19-23. |
| LaFrance WC Jr, Lauterbach EC, Coffey CE, Salloway SP, Kaufer DI, Reeve A, Royall DR, Aylward E, Rummans TA, Lovell MR. "The use of herbal alternative medicines in neuropsychiatry. A report of the ANPA Committee on Research." The Journal of neuropsychiatry and clinical neurosciences, vol. 12, no. 2, 2000, pp. 177-92. |
DoD 9/30/17-8/31/24
Neuroimaging Biomarker for Seizures
P.I.s LaFrance Jr, W Curt; Szaflarski, Jerzy P.
NPNI/BIBS 7/1/15-6/30/16
New Frontiers Award A Biosensor in the Epilepsy Monitoring Unit
P.I.s Blum, Andrew; LaFrance, Jr, W Curt; Trucculo, Wilson
Brown Diagnostic Imaging 1/1/12-12/31/12
DDI Research Seed Grant Concussions in High School and College Athletes: Predictors for Recovery and Outcome
P.I. Rogg, Jeff
NIH NIMH K23 7/15/11-4/30/2016
1 K23 MH092735 Psychogenic Tremor: Functional Magnetic Resonance Study on Emotional Processing
P.I. Espay, Alberto
Epilepsy Foundation (EF) 7/1/11-6/30/12
925120 Risk Factors in Pediatric Nonepileptic Seizures
P.I. Plioplys, Sigita
Epilepsy Foundation 7/1/11-6/30/12
213382 Brain MRI Quantification in Epilepsy and Depression
co-P.I.s Davis, Jennifer; LaFrance, Jr, W Curt
American Epilepsy Society January 2010-December 2011
Research Infrastructure Award Multi-site pilot RCT for PNES
P.I. LaFrance, Jr., W Curt
Epilepsy Foundation January 2009-December 2010
122982 Treatment Trial for Psychogenic NES
P.I. LaFrance, Jr., W Curt
Rhode Island Hospital July 2008-June 2009
Infrastructure Research Grant Randomized Trial for Psychogenic NES
P.I. LaFrance, Jr, W Curt
Siravo Foundation October 2008-September 2009
Medical Research Advisory Board A lab test differentiating epilepsy from NES
P.I. LaFrance, Jr., W Curt
National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) 1K23 NS45902-01 July 2003 June 2009
Treatments for Psychogenic Nonepileptic Seizures.
P.I. LaFrance, Jr., W. Curt.
Lifespan March 2007-February 2008
Pilot Study of the Genetics of Psychogenic Movement Disorder and Nonepileptic Seizures
LaFrance, Jr., W. Curt.
Epilepsy Foundation July 2006-June 2007
Targeted Research Initiative in Mood Mood and Executive Function in Epilepsy.
Co-P.I.s Davis, Jennifer; LaFrance, Jr., W. Curt.
NIH National Institute of Mental Health (NIMH) 5T32 MH19987-04 Institutional NRSA June 2001-June 2003
Research Training in Combined Treatment Modalities.
P.I. Shea, Tracie.
Books, Chapters and other publications:
LaFrance Jr WC, Schachter SC, Eds. Gates and Rowan's Nonepileptic Seizures. 4th Edition. Cambridge; New York: Cambridge University Press; 2018.
LaFrance Jr WC, Wincze J. Treating Nonepieptic Seizures: Therapist Guide. New York, Oxford University Press. 2015.
Reiter J, Andrews D, Reiter C, LaFrance Jr WC. Taking Control of Your Seizures: Workbook. New York, Oxford University Press. 2015.
Schachter SC, LaFrance Jr WC, Eds. Gates and Rowan's Nonepileptic Seizures. 3rd Edition. Cambridge; New York: Cambridge University Press; 2010.
LaFrance Jr WC. Psychogenic nonepileptic "seizures" or "attacks"?: It's not just semantics: Seizures. Neurology 2010;75(1):87-8.
LaFrance Jr WC, Kanner AM. Epilepsy. In: Friedman J, Jeste DV, editors. Current Clinical Neurology: Psychiatry for Neurologists. New Jersey: Humana Press, Inc.; 2006. p. 191-208.
Salloway S, Harrington C, Orr D, LaFrance Jr WC. Diagnosis and Treatment of Dementias. In Stoudemire A, Fogel BS and Greenberg D, Eds. Psychiatric Care of the Medical Patient. 2nd Ed., 1999, New York: Oxford University Press.
Rausch JL, LaFrance C, Stahl SM. Serotonin receptor-specific mediation of antidepressant treatment effects in depressed patients. International Review of Psychiatry. 1995;7(1):85-98.
| Year | Degree | Institution |
|---|---|---|
| 2007 | MPH | Brown University |
| 1995 | MD | Medical College of Georgia |
| 1991 | BA | Wake Forest University |
| Fellow in Research | The Warren Alpert Medical School of Brown University, Rhode Island Hospital | 2001-2003 | Providence, RI |
| Chief Resident | Butler Hospital, neuropsychiatry | 2000-2001 | |
| Chief Resident | Rhode Island Hospital, neurology | 1998-1999 | |
| Resident | The Warren Alpert Medical School of Brown University, Rhode Island Hospital; Butler Hospital, neurology and psychiatry | 1996-2001 | Providence, RI |
| Intern | The Warren Alpert Medical School of Brown University, Rhode Island Hospital, internal medicine | 1995-1996 | Providence, RI |
MAP International -- Reader's Digest International Fellowship, HIV/Tropical Disease Medical Elective Siriraj Hospital, Bangkok, Thailand, 1995
Award for Outstanding Performance in Neurology, Medical College of Georgia, Department of Neurology, 1995
American Academy of Neurology Annual Resident Scholarship, Toronto, Ontario, Canada, 1999
Psychiatry Resident Award of Excellence, Janssen Research Foundation, New Orleans, LA., 2001
American Psychiatric Assoc. (APA) Research Colloquium Scholarship for Junior Investigators, New Orleans, LA, 2001
National Institutes of Mental Health (NIMH), Summer Research Institute Participant, San Diego, Calif., 2001
American Neuropsychiatric Association, Career Development Award, Honolulu, Hawaii, (2003-4)
Mentored Patient-Oriented Research Career Development Award, K-23, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS), 2003-8
APA Research Colloquium Scholarship for Advanced Junior Investigators, New York, NY, 2004
Marquis Who's Who in the World, 2007-
Visiting Professorship, International League Against Epilepsy, 2009
Professional Advisory Board, Epilepsy Foundation, 2010-8
Fellow of the American Academy of Neurology, 2011-
Distinguished Fellow of the American Psychiatric Association, 2012-
Fellow of the American Neuropsychiatric Association, 2012-
American Academy of Neurology Dreifuss-Penry Epilepsy Award, 2013
Board of Directors, Functional Neurological Disorder Society, 2019-22
Epilepsy Foundation New England, Honoree, 2023
Fellow of the American Epilepsy Society, 2023-
| Name | Title |
|---|---|
| Baird, Grayson | Associate Professor of Diagnostic Imaging |
| Blum, Andrew | Professor of Neurology |
| Davis, Jennifer | Associate Professor of Psychiatry and Human Behavior, Clinician Educator |
| Friedman, Joseph | Professor of Neurology |
| Keitner, Gabor | Professor of Psychiatry and Human Behavior |
| Machan, Jason | Associate Professor of Surgery (Research), Associate Professor of Orthopaedics (Research) |
| Miller, Ivan | Professor of Psychiatry and Human Behavior |
| Papandonatos, George | Professor of Biostatistics (Research) |
| Stopa, Edward | Professor of Pathology and Laboratory Medicine, Professor of Neurosurgery |
| Tremont, Geoffrey | Professor Emeritus of Psychiatry and Human Behavior |
| Truccolo, Wilson | Pablo J. Salame Goldman Sachs Associate Professor of Computational Neuroscience |
-Functional Neurological Disorder Society, 2019-
Founding Member, 2019
Board of Directors, 2019-2022
-American Epilepsy Society, 2003-
Fellow, 2023-
-American Neuropsychiatric Association, 1997-
Fellow, 2012-
Council Advisory Board, 2019-2021
-American Psychiatric Association, 1994-
Distinguished Fellow, 2012-
-American Academy of Neurology, 1994-
Fellow, 2011-
-Christian Medical and Dental Associations 1992-
| Certification | American Board of Psychiatry and Neurology, Psychiatry | 2003-Present | #52706 |
| Certification | American Board of Psychiatry and Neurology, Neurology | 2002-Present | #51318 |
| Certification | National Institutes of Health, Protection of human research subjects | 2000- | |
| Medical License | Rhode Island | 1998-Present | #9737 |
| Director. Veterans Health Administration, 2021- |
| Clinical Lead. VA National Telemental Health Center, 2013- |
| Staff Physician. Providence VA Medical Center, 2012-Present |
| Neuropsychiatrist. Rhode Island Hospital, 2004-Present |
| Inaugural Director of Neuropsychiatry and Behavioral Neurology. Rhode Island Hospital, 2003-2023 |
| Staff Neurologist. Rhode Island Hospital, 2001-Present |
| Staff Psychiatrist. Rhode Island Hospital, 2001-Present |
| Neuropsychiatry Chief Resident. Butler Hospital, 2000-2001 |
| Neurology Chief Resident. Rhode Island Hospital, 1998-1999 |
Former Director of the Combined Neurology/Psychiatry Residency at Brown University
Introduction to Neuropsychiatry
The Neuropsychiatric Exam
Neuropsychiatric Aspects of Epilepsy
Traumatic Brain Injury
Somatoform Disorders
Forensic Neurology and Neuroimaging
Dr. LaFrance also supervises undergraduate and medical students and residents conducting neuropsychiatric research.
BIOL 1950/1960 Directed Research/Independent Study
