Charles A. Vaslet, Ph.D. is Assistant Professor (Research) and Director of the Molecular Pathology Core Research Laboratory in the Department of Pathology and Laboratory Medicine at Brown University. He is co-principal investigator of NIH-funded research grants on the molecular mechanisms of asbestos-induced cancer and on nano-toxicology. He has extensive experience and expertise in molecular pathology and biotechnology.
Mulcahy LR, Vaslet CA, Nillni EA. Prohormone-convertase 1 processing enhances post-golgi sorting of prothyrotropin releasing hormone-derived peptides. Journal of Biological Chemistry 280: 39818-39826.
Altomare DA, Vaslet CA, Skele KL, De Rienzo A, Devarajan K, Jhanwar SC, McClatchey AI, Kane AB, Testa JR. A mouse model recapitulating molecular features of human mesothelioma. Cancer Research 65: 8090-8095.
Posner SF, Vaslet CA, Jurofcik M, Lee A, Seidah NG, Nillni EA. Stepwise postranslatiuonal processing of progrowth hormone-releasing hormone (proGHRH) polypeptide by furin and PC1. Endocrine 23: 1-15.
Vaslet CA, Messier NJ, Kane AB. Accelerated progression of asbestos-induced mesotheliomas in heterozygous p53 +/- mice. Toxicological Sciences 2002 68: 331-338.
Nillni EA, Vaslet CA, Harris M, Hollenberg A, Bjorbaek C, Flier JS. Leptin regulates prothyrotropin-releasing hormone biosynthesis: Evidence for direct and indirect pathways. Journal of Biological Chemistry 275:36124-36133.
Gruppuso PA, Boylan JM, Vaslet CA. Identification of candidate growth regulating genes that are over-expressed in late gestation fetal liver in the rat. Biochimica et Biophysica Acta 93471:1-6.
Goodglick LA, Vaslet CA, Messier NJ, Kane AB. Growth factor responses and protooncogene expression of murine mesothelial cell lines derived from asbestos-induced mesotheliomas. Toxicologic Pathology 25: 565-573.
Cistulli CA, Sorger T, Marsella JM, Vaslet CA, Kane AB. Spontaneous p53 mutation in murine mesothelial calls: Increased sensitivity to DNA damage induced by asbestos and ionizing radiation. Toxicology and Applied Pharmacology 141: 264-271,
|1974||MS||West Virginia University|
|Hurt, Robert||Professor of Engineering|
|Nillni, Eduardo||Professor Emeritus of Medicine (Research), Professor Emeritus of Molecular Biology, Cell Biology and Biochemistry (Research)|