Dr. Beveridge is an Assistant Professor in the Department of Orthopeadics where her research investigates the interactions between biological, mechanical, and neuromuscular mechanisms that drive post-traumatic osteoarthritis after intra-articular joint injury. She received her doctorate in Biomedical Engineering from the University of Calgary in 2012 and then completed two postdoctoral fellowships, the first at the University of Calgary (2012-2015) and the second at Brown University in the Bioengineering Laboratory (2015-2018). Before rejoining the Department in November 2022, Dr. Beveridge founded the Movement and Biomechanics Laboratory at the Cleveland Clinic where she was Assistant Staff and Assistant Professor at Case Western Reserve University Biomedical Engineering Departments from 2019-2022. Recent projects have used imaging, computational modeling, and biomechanics techniques to interrogate functional changes that modulate the mechanobiology of soft tissue degradation following injury, with particular emphasis on anterior cruciate ligament (ACL) injury and surgery. Dr. Beveridge received the Early-Career Award from the Journal of Orthopaedic Research in 2019 for her work with Dr. Fleming to develop an imaging approach to estimate ACL properties after surgery. Dr. Beveridge’s career development and early research has been supported by the Canadian Institutes of Health Research, Alberta Innovates Health Solutions, The Arthritis Society, the Natural Sciences and Engineering Research Council of Canada, and the National Institutes of Health as a K99/R00 scholar.
| Zandiyeh, Payam, Parola, Lauren R., Costa, Meggin Q., Hague, Madalyn J., Molino, Janine, Fleming, Braden C., Beveridge, Jillian E. "Long-Term Bilateral Neuromuscular Function and Knee Osteoarthritis after Anterior Cruciate Ligament Reconstruction." Bioengineering, vol. 10, no. 7, 2023, pp. 812. |
| Flannery SW, Beveridge JE, Proffen BL, Walsh EG, BEAR Trial Team, Kramer DE, Murray MM, Kiapour AM, Fleming BC. "Predicting anterior cruciate ligament failure load with T(2)* relaxometry and machine learning as a prospective imaging biomarker for revision surgery." Scientific reports, vol. 13, no. 1, 2023, pp. 3524. |
| Flannery SW, Kiapour AM, Edgar DJ, Murray MM, Beveridge JE, Fleming BC. "A transfer learning approach for automatic segmentation of the surgically treated anterior cruciate ligament." Journal of Orthopaedic Research, vol. 40, no. 1, 2022, pp. 277-284. |
| Sun C, Cao C, Zhao T, Guo H, Fleming BC, Owens B, Beveridge J, McAllister S, Wei L. "A2M inhibits inflammatory mediators of chondrocytes by blocking IL-1β/NF-κB pathway." Journal of Orthopaedic Research, vol. 41, no. 1, 2022, pp. 241-248. |
| Zandiyeh P, Parola LR, Fleming BC, Beveridge JE. "Wavelet analysis reveals differential lower limb muscle activity patterns long after anterior cruciate ligament reconstruction." Journal of Biomechanics, vol. 133, 2022, pp. 110957. |
| Behnke AL, Parola LR, Karamchedu NP, Badger GJ, Fleming BC, Beveridge JE. "Neuromuscular function in anterior cruciate ligament reconstructed patients at long-term follow-up." Clinical biomechanics (Bristol, Avon), vol. 81, 2021, pp. 105231. |
| Shekarforoush M, Barton KI, Beveridge JE, Scott M, Martin CR, Muench G, Heard BJ, Sevick JL, Hart DA, Frank CB, Shrive NG. "Alterations in Joint Angular Velocity Following Traumatic Knee Injury in Ovine Models." Annals of Biomedical Engineering, vol. 47, no. 3, 2019, pp. 790-801. |
| Beveridge JE, Proffen BL, Karamchedu NP, Chin KE, Sieker JT, Badger GJ, Kiapour AM, Murray MM, Fleming BC. "Cartilage Damage Is Related to ACL Stiffness in a Porcine Model of ACL Repair." Journal of Orthopaedic Research, vol. 37, no. 10, 2019, pp. 2249-2257. |
| Shekarforoush M, Beveridge JE, Hart DA, Frank CB, Shrive NG. "Correlation between translational and rotational kinematic abnormalities and osteoarthritis-like damage in two in vivo sheep injury models." Journal of Biomechanics, vol. 75, 2018, pp. 67-76. |
| Heard BJ, Beveridge JE, Atarod M, O'Brien EJ, Rolian C, Frank CB, Hart DA, Shrive NG. "Analysis of change in gait in the ovine stifle: normal, injured, and anterior cruciate ligament reconstructed." BMC Musculoskeletal Disorders, vol. 18, no. 1, 2017, pp. 212. |
| Beveridge JE, Machan JT, Walsh EG, Kiapour AM, Karamchedu NP, Chin KE, Proffen BL, Sieker JT, Murray MM, Fleming BC. "Magnetic resonance measurements of tissue quantity and quality using T2 * relaxometry predict temporal changes in the biomechanical properties of the healing ACL." Journal of Orthopaedic Research, vol. 36, no. 6, 2017, pp. 1701-1709. |
| Beveridge, Jillian E., Walsh, Edward G., Murray, Martha M., Fleming, Braden C. "Sensitivity of ACL volume and T 2 ∗ relaxation time to magnetic resonance imaging scan conditions." Journal of Biomechanics, vol. 56, 2017, pp. 117-121. |
| Beveridge JE, Atarod M, Heard BJ, O'Brien EEJ, Frank CB, Shrive NG. "Relationship between increased in vivo meniscal loads and abnormal tibiofemoral surface alignment in ACL deficient sheep is varied." Journal of Biomechanics, vol. 49, no. 16, 2016, pp. 3824-3832. |
| Lichti DD, Sharma GB, Kuntze G, Mund B, Beveridge JE, Ronsky JL. "Rigorous geometric self-calibrating bundle adjustment for a dual fluoroscopic imaging system." IEEE transactions on medical imaging, vol. 34, no. 2, 2015, pp. 589-98. |
| Beveridge JE, Heard BJ, Brown JJ, Shrive NG, Frank CB. "A new measure of tibiofemoral subchondral bone interactions that correlates with early cartilage damage in injured sheep." Journal of Orthopaedic Research, vol. 32, no. 10, 2014, pp. 1371-80. |
| Beveridge JE, Shrive NG, Frank CB. "Repeatability and precision of a weighted centroid method for estimating dynamic in vivo tibiofemoral surface interactions in sheep." Computer Methods in Biomechanics and Biomedical Engineering, vol. 17, no. 16, 2014, pp. 1853-63. |
| O'Brien EJ, Beveridge JE, Huebner KD, Heard BJ, Tapper JE, Shrive NG, Frank CB. "Osteoarthritis develops in the operated joint of an ovine model following ACL reconstruction with immediate anatomic reattachment of the native ACL." Journal of Orthopaedic Research, vol. 31, no. 1, 2013, pp. 35-43. |
| Beveridge JE, Heard BJ, Shrive NG, Frank CB. "Tibiofemoral centroid velocity correlates more consistently with cartilage damage than does contact path length in two ovine models of stifle injury." Journal of Orthopaedic Research, vol. 31, no. 11, 2013, pp. 1745-56. |
| Frank CB, Beveridge JE, Huebner KD, Heard BJ, Tapper JE, O'Brien EJ, Shrive NG. "Complete ACL/MCL deficiency induces variable degrees of instability in sheep with specific kinematic abnormalities correlating with degrees of early osteoarthritis." Journal of Orthopaedic Research, vol. 30, no. 3, 2012, pp. 384-92. |
| Beveridge JE, Shrive NG, Frank CB. "Meniscectomy causes significant in vivo kinematic changes and mechanically induced focal chondral lesions in a sheep model." Journal of Orthopaedic Research, vol. 29, no. 9, 2011, pp. 1397-405. |
| Darcy SP, Rosvold JM, Beveridge JE, Corr DT, Brown JJ, Sutherland CA, Marchuk LL, Frank CB, Shrive NG. "A comparison of passive flexion-extension to normal gait in the ovine stifle joint." Journal of Biomechanics, vol. 41, no. 4, 2008, pp. 854-60. |
| Howard RA, Rosvold JM, Darcy SP, Corr DT, Shrive NG, Tapper JE, Ronsky JL, Beveridge JE, Marchuk LL, Frank CB. "Reproduction of in vivo motion using a parallel robot." Journal of Biomechanical Engineering, vol. 129, no. 5, 2007, pp. 743-9. |
Dr. Beveridge’s Movement and Biomechanics Lab focuses on unraveling the intertwined mechanobiology crosstalk that occurs within the joint after intra-articular injury. The lab leverages motion capture and imaging technologies that can be used interchangeably between preclinical and clinical research arms of her research program to facilitate rapid translation of patient-specific interventions that promote long-term joint health.
My research interests focus on knee joint injuries and the structural and functional changes that may contribute to posttraumatic osteoarthritis (PTOA). Over the past decade, I have accumulated experience in translational and clinical research using advanced imaging modalities and techniques that have provided the foundation to build an impactful research program. These techniques include optical- and biplane videoradiography motion capture, muscle electromyography, quantitative magnetic resonance (MR) imaging, soft tissue mechanical testing, and custom-written software pipelines for biomechanical data reduction and analyses. By integrating information from these platforms, I have identified relationships between dynamic in vivo joint and neuromuscular function, cartilage structure, and ligament biomechanics that may contribute to PTOA initiation and progression following anterior cruciate ligament and meniscus injuries. There are three ongoing projects in the lab (1) in a multicenter study, contributing to the development and deployment of Slicer-Autoscoper, a software program used to extract skeletal kinematics from 3D and 4D imaging modalities originally developed by Brown University investigators; (2) investigating whether neuromuscular function could explain strength differences that have been observed between conventional anterior cruciate ligament (ACL) reconstruction and bridge enhanced ACL restoration; and (3) determining the crosstalk between biological and mechanical drivers of PTOA in a preclinical animal model and testing interventions that attenuate cartilage damage.
Active Research Support
Past Research Support
Research Support as a Trainee
2015-2018 AIHS Postgraduate Fellowship ($50,000 with $5,000 research allowance per annum [p.a.]; completed 2015)
2013-2016 The Arthritis Society Post-Doctoral Fellowship ($20,000 p.a.; completed 2015)
2013-2015 NSERC CREATE Post-Doctoral Fellowship ($20,000 p.a.)
2012-2013 McCaig Professorship Scholarship ($36,000 p.a.)
2006-2009 Bone & Joint Training Program ($3,000 with $2,000 travel allowance p.a.)
2006-2011 AHFMR – Full-time Studentship ($20,000 with $1,500 research allowance p.a.)
Keynote Speaker
Invited Speaker (12)
Other Seminars Given (17)
| Year | Degree | Institution |
|---|---|---|
| 2012 | PhD | University of Calgary |
| Postdoctoral Fellow | Brown University, Rhode Island Hospital, The Miriam Hospital & the Warren Alpert Medical School of Brown University, Department of Orthopaedic Surgery, Bioengineering Lab | 2015-2019 | Providence, RI, USA |
| Postdoctoral Fellow | University of Calgary, Department of Mechanical Engineering | 2012-2015 | Calgary, Alberta, Canada |
| Research Assistant | University of Calgary, Department of Orthopaedic Surgery | 2004-2012 |
2020 *Journal of Orthopaedic Research Early Career Award
2010-2014 University of Calgary, AIHS Team Grant in OA Travel Award (3 Awards)
2010-2014 University of Calgary, CREATE Travel Award (3 Awards)
2013 *Arthritis Alliance of Canada, Best Research Proposal Poster
2013 AIHS Alberta OA Team Meeting, Best Poster
2007-2011 University of Calgary, Biomedical Engineering Bursary
2009 *Canadian Institutes of Health Research (CIHR), Travel Award (1 of 40)
2008 *International Symposium on Ligaments & Tendons (ISL&T) Meeting, Best Poster
2007 University of Calgary, Medical Science Travel Award
2007 *Canadian Arthritis Network (CAN) Annual Scientific Meeting Travel Award (1 of 7)
2006 CIHR Bone & Joint Training Program Meeting, Best Poster
2005 Government of Alberta, Continuing Education Scholarship
2004 University of Calgary, Faculty of Graduate Studies Scholarship
2004 University of Calgary, Dean’s Entrance Scholarship| Name | Title |
|---|---|
| Brainerd, Elizabeth | Robert P. Brown Professor of Biology, Professor of Medical Science |
| Crisco, Joseph | Henry F. Lippitt Professor of Orthopedics, Professor of Engineering (Research) |
| Fleming, Braden | Lucy Lippitt Professor of Orthopaedics, Professor of Engineering |
| Owens, Brett | Professor of Orthopaedics, Professor of Epidemiology |
| Walsh, Edward | Associate Professor of Brain Science (Research) |
Orthopaedic Research Society, Member
International Society of Biomechanics, Member
American Orthopaedic Society for Sports Medicine
Osteoarthritis Research Society International, Associate Member, Past Member
Canadian Society of Biomechanics, Past Member
Ontario Kinesiology Association, Past Member
| Assistant Professor. Rhode Island Hospital, The Miriam Hospital & the Warren Alpert Medical School of Brown University, 2022-Present |
| Assistant Professor. Case Western Reserve University, 2020-2022 |
| Assistant Staff. Cleveland Clinic Foundation, 2019-2000 |
I offer Research for Credit courses on a case-by-case basis for graduate students working in my laboratory. I also serve as a guest lecturer and topic specialist in courses related to orthopaedic biomechanics and biomedical engineering.
Lectures Given:
