Phyllis A. Dennery is the Sylvia Kay Hassenfeld Chair of Pediatrics at the Warren Alpert School of Medicine of Brown University, Pediatrician-in-Chief, Rhode Island Hospital and Medical Director of Hasbro Children’s Hospital. She is also a Professor of Molecular Biology, Cell Biology and Biochemistry at Brown University.
She obtained her B.S. in Biology from McGill University in Montreal, Canada. After receiving her medical degree from Howard University in Washington, DC, Dr. Dennery completed a residency in Pediatrics at Children’s Hospital National Medical Center also in Washington, DC and a fellowship in Neonatal-Perinatal Medicine at Case Western Reserve University (Rainbow Babies and Children’s Hospital) in Cleveland, Ohio.
Dr Dennery is an active member of many professional and scientific societies. She served as the President of the Society for Pediatric Research in 2007-08 and as the President of the International Pediatric Research Foundation in 2010-11. She has served as the Chair of the Credential Committee for the Neonatal/Perinatal Sub-board of the American Board of Pediatrics and has served as an Associate Editor for the scientific journals Free Radicals in Biology and Medicine and Pediatrics, where she oversaw the State of the Art series. She was also appointed to the Secretary of Health and Human Services Advisory Committee on Infant Mortality and served on the Community Action Team of the Medical Examiner’s Office in Philadelphia focused on infant mortality. She co-led the NASEM report on enhancing pediatric research at the NIH.
Dr. Dennery was elected to the National Academy of Medicine in 2014, elected as a fellow of the Society for Free Radicals in Biology and Medicine in 2014, the American Thoracic Society in 2022, and to the Association of American Physicians in 2015. She serves on the national board of the March of Dimes.
For over 35 years, Dr. Dennery’s laboratory has focused understanding mechansisms of neonatal lung injury and repair. She investigates bronchopulmonary dysplasia (BPD) a chronic lung disease of premature infants caused in part by oxygen and ventilatory support, with long-term respiratory consequences that can persist into adulthood. She has discovered that macrophage senescence is a hallmark of BPD in an animal model. She also has defined the developmental regulation of senescence in the neonatal lung. This understanding will provide a foundation for developing targeted therapies that modulate macrophage metabolism and senescence to prevent or treat lung injury in premature infants.
Her clinical interests are in neonatal jaundice, bronchopulmonary dysplasia and the long-term consequences of prematurity as well as on perinatal health disparities and the impact of race in Medicine. She is the Executive Committee chair for a Pediatric clinical trials network funded by the NIH.
| Ambalavanan, Namasivayam, Weese-Mayer, Debra E., Hibbs, Anna Maria, Claure, Nelson, Carroll, John L., Moorman, J. Randall, Bancalari, Eduardo, Hamvas, Aaron, Martin, Richard J., Di Fiore, Juliann M., Indic, Premananda, Kemp, James S., Dormishian, Alaleh, Krahn, Katy N., Qiu, Jiaxing, Dennery, Phyllis A., Ratcliffe, Sarah J., Troendle, James F., Lake, Douglas E., Fairchild, Karen D., Zimmet, Amanda M., Lonergan, Erin K, Rand, Casey M., Zadell, Arlene, Nakhmani, Arie, Carlo, Waldemar A., Laney, Deborah, Travers, Colm P., Aguilar, Ana Cecilia, Schott, Alini, Hoffmann, Julie, Aggarwal, Neil, Baizer, Lawrence, Ghofrani, Peyvand, Laposky, Aaron D., Natarajan, Aruna, Schmetter, Barry, Gauda, Estelle B., Davis, Jonathan M., Keller, Roberta L., Khemani, Robinder G., Moore, Renee H., Weiss, Elliott M., Camblos, Amy K., Duda, Gina M., Flower, Abigail A., Fowler, Steven A., Pramoonjago, Patcharin, Rumpel, Craig A., Fadl-Alla, Allaa, Boswell, Lynn D., Carroll, Michael S., DeRegnier, Raye-Ann, Hopkins, Bradley S., Krishnamurthi, Narayanan, Paydarfar, David, Salisbury, Elisabeth, Troxler, Bradley, Colvin, Ryan, Egan, Joey, Eiden, Elise, Hoover, Jeffery, Linneman, Laura, Mammel, Daniel, McLeland, Michael, Pyles, Harley, Warner, Barbara. "Cardiorespiratory Monitoring Data to Predict Respiratory Outcomes in Extremely Preterm Infants." American Journal of Respiratory and Critical Care Medicine, vol. 208, no. 1, 2023, pp. 79-97. |
| Daniels TE, Zitkovsky EK, Kunicki ZJ, Price DJ, Peterson AL, Dennery PA, Kao HT, Price LH, Tyrka AR, Abrantes AM. "Corrigendum to "Associations of circulating cell-free DNA, C-reactive protein, and cardiometabolic risk among low-active smokers with elevated depressive symptoms" [Brain Behav. Immun. - Health 25 (2022) 100519]." Brain, behavior, & immunity - health, vol. 27, 2023, pp. 100583. |
| Cabana, Michael D., de Alarcon, Pedro A., Allen, Erin, Bean, Xylina D., Brophy, Patrick D., Degnon, Laura, First, Lewis R., Dennery, Phyllis A., Salazar, Juan C., Schleien, Charles, St. Geme, Joseph W., Parra-Roide, Lilia, Walker-Harding, Leslie R. "Diversity in Pediatrics Department Leadership Positions." The Journal of Pediatrics, 2023, pp. 113557. |
| Teape, Daniella, Peterson, Abigail, Ahsan, Nagib, Ellis, Kimberlyn, Correia, Nicholas, Luo, Ryan, Hegarty, Katy, Yao, Hongwei, Dennery, Phyllis. "Hyperoxia impairs intraflagellar transport and causes dysregulated metabolism with resultant decreased cilia length." American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 324, no. 3, 2023, pp. L325-L334. |
| Yao, Hongwei, Wallace, Joselynn, Peterson, Abigail L., Scaffa, Alejandro, Rizal, Salu, Hegarty, Katy, Maeda, Hajime, Chang, Jason L., Oulhen, Nathalie, Kreiling, Jill A., Huntington, Kelsey E., De Paepe, Monique E., Barbosa, Guilherme, Dennery, Phyllis A. "Timing and cell specificity of senescence drives postnatal lung development and injury." Nature Communications, vol. 14, no. 1, 2023. |
| Scaffa, Alejandro, Tollefson, George A., Yao, Hongwei, Rizal, Salu, Wallace, Joselynn, Oulhen, Nathalie, Carr, Jennifer F., Hegarty, Katy, Uzun, Alper, Dennery, Phyllis A. "Identification of Heme Oxygenase-1 as a Putative DNA-Binding Protein." Antioxidants, vol. 11, no. 11, 2022, pp. 2135. |
| Maeda H, Yao H, Go H, Huntington KE, De Paepe ME, Dennery PA. "Involvement of miRNA-34a regulated Krüppel-like factor 4 expression in hyperoxia-induced senescence in lung epithelial cells." Respiratory Research, vol. 23, no. 1, 2022, pp. 340. |
| Chang JL, Gong J, Rizal S, Peterson AL, Chang J, Yao C, Dennery PA, Yao H. "Upregulating carnitine palmitoyltransferase 1 attenuates hyperoxia-induced endothelial cell dysfunction and persistent lung injury." Respiratory Research, vol. 23, no. 1, 2022, pp. 205. |
| "Hyperoxia causes senescence and increases glycolysis in cultured lung epithelial cells." Physiol. Rep, 2021. |
| "Loss of the transcriptional repressor Rev-erbα upregulates metabolism and proliferation in cultured mouse embryonic fibroblasts." 2021. |
| Gillis SP, Yao H, Rizal S, Maeda H, Chang J, Dennery PA. "Loss of the transcriptional repressor Rev-erbα upregulates metabolism and proliferation in cultured mouse embryonic fibroblasts." Scientific reports, vol. 11, no. 1, 2021, pp. 12356. |
| Yue L, Lu X, Dennery PA, Yao H. "Metabolic dysregulation in bronchopulmonary dysplasia: Implications for identification of biomarkers and therapeutic approaches." Redox Biology, 2021, pp. 102104. |
| Scaffa A, Yao H, Oulhen N, Wallace J, Peterson AL, Rizal S, Ragavendran A, Wessel G, De Paepe ME, Dennery PA. "Single-cell transcriptomics reveals lasting changes in the lung cellular landscape into adulthood after neonatal hyperoxic exposure." Redox Biology, 2021, pp. 102091. |
| Gong J, Feng Z, Peterson AL, Carr JF, Lu X, Zhao H, Ji X, Zhao YY, De Paepe ME, Dennery PA, Yao H. "The pentose phosphate pathway mediates hyperoxia-induced lung vascular dysgenesis and alveolar simplification in neonates." JCI insight, vol. 6, no. 5, 2021. |
| Gong J, Feng Z, Peterson AL, Carr JF, Vang A, Braza J, Choudhary G, Dennery PA, Yao H. "Endothelial to mesenchymal transition during neonatal hyperoxia-induced pulmonary hypertension." The Journal of Pathology, vol. 252, no. 4, 2020, pp. 411-422. |
| Go, Hayato, Maeda, Hajime, Miyazaki, Kyohei, Maeda, Ryo, Kume, Yohei, Namba, Fumihiko, Momoi, Nobuo, Hashimoto, Koichi, Otsuru, Satoru, Kawasaki, Yukihiko, Hosoya, Mitsuaki, Dennery, Phyllis A. "Extracellular vesicle miRNA-21 is a potential biomarker for predicting chronic lung disease in premature infants." American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 318, no. 5, 2020, pp. L845-L851. |
| Yao, Hongwei, Peterson, Abigail L., Li, Jie, Xu, Haiyan, Dennery, Phyllis A. "Heme Oxygenase 1 and 2 Differentially Regulate Glucose Metabolism and Adipose Tissue Mitochondrial Respiration: Implications for Metabolic Dysregulation." International Journal of Molecular Sciences, vol. 21, no. 19, 2020, pp. 7123. |
| Carr JF, Garcia D, Scaffa A, Peterson AL, Ghio AJ, Dennery PA. "Heme Oxygenase-1 Supports Mitochondrial Energy Production and Electron Transport Chain Activity in Cultured Lung Epithelial Cells." International Journal of Molecular Sciences, vol. 21, no. 18, 2020. |
| Peterson AL, Carr JF, Ji X, Dennery PA, Yao H. "Hyperoxic Exposure Caused Lung Lipid Compositional Changes in Neonatal Mice." Metabolites, vol. 10, no. 9, 2020. |
| "Short exposure to hyperoxia causes cultured lung epithelial cell mitochondrial dysregulation and alveolar simplification in mice." 2020. |
| Lu X, Gong J, Dennery PA, Yao H. "Endothelial-to-mesenchymal transition: Pathogenesis and therapeutic targets for chronic pulmonary and vascular diseases." Biochemical pharmacology, vol. 168, 2019, pp. 100-107. |
| Dennery, Phyllis A., Di Fiore, Juliann M., Ambalavanan, Namasivayam, Bancalari, Eduardo, Carroll, John L., Claure, Nelson, Hamvas, Aaron, Hibbs, Anna Maria, Indic, Premananda, Kemp, James, Krahn, Katy N., Lake, Douglas, Laposky, Aaron, Martin, Richard J., Natarajan, Aruna, Rand, Casey, Schau, Molly, Weese-Mayer, Debra E., Zimmet, Amanda M., Moorman, J. Randall. "Pre-Vent: the prematurity-related ventilatory control study." Pediatric Research, vol. 85, no. 6, 2019, pp. 769-776. |
| Yao, Hongwei, Gong, Jiannan, Peterson, Abigail L., Lu, Xuexin, Zhang, Peng, Dennery, Phyllis A. "Fatty Acid Oxidation Protects against Hyperoxia-induced Endothelial Cell Apoptosis and Lung Injury in Neonatal Mice." American Journal of Respiratory Cell and Molecular Biology, vol. 60, no. 6, 2018, pp. 667-677. |
| Zhao H, Dennery PA, Yao H. "Metabolic reprogramming in the pathogenesis of chronic lung diseases including BPD, COPD, and pulmonary fibrosis." American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 314, no. 4, 2018, pp. L544-L554. |
| Dennery PA, Carr J, Peterson A, Yao H. "THE ROLE OF MITOCHONDRIAL FATTY ACID USE IN NEONATAL LUNG INJURY AND REPAIR." Transactions of the American Clinical and Climatological Association, vol. 129, 2018, pp. 195-201. |
| Ito, Masato, Nagano, Nobuhiko, Arai, Yukio, Ogawa, Ryo, Kobayashi, Shingo, Motojima, Yukiko, Go, Hayato, Tamura, Masanori, Igarashi, Kazuhiko, Dennery, Phyllis A., Namba, Fumihiko. "Genetic ablation of Bach1 gene enhances recovery from hyperoxic lung injury in newborn mice via transient upregulation of inflammatory genes." Pediatric Research, 2017. |
| Dennery P, Ryan RM. "Pursuing Research Careers in Pediatrics: Hope Springs Eternal." The Journal of Pediatrics, 2017. |
| Go H, La P, Namba F, Ito M, Yang G, Brydun A, Igarashi K, Dennery PA. "MiR-196a regulates heme oxygenase-1 by silencing Bach1 in the neonatal mouse lung." American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 311, no. 2, 2016, pp. L400-11. |
| Namba F, Ogawa R, Ito M, Watanabe T, Dennery PA, Tamura M. "Sex-related differences in long-term pulmonary outcomes of neonatal hyperoxia in mice." Experimental lung research, vol. 42, no. 2, 2016, pp. 57-65. |
| Sengupta S, Yang G, O'Donnell JC, Hinson MD, McCormack SE, Falk MJ, La P, Robinson MB, Williams ML, Yohannes MT, Polyak E, Nakamaru-Ogiso E, Dennery PA. "The circadian gene Rev-erbα improves cellular bioenergetics and provides preconditioning for protection against oxidative stress." Free Radical Biology and Medicine, vol. 93, 2016, pp. 177-89. |
| Forman, Henry Jay, Augusto, Ohara, Brigelius-Flohe, Regina, Dennery, Phyllis A., Kalyanaraman, Balaraman, Ischiropoulos, Harry, Mann, Giovanni E., Radi, Rafael, Roberts, L. Jackson, Vina, Jose, Davies, Kelvin J.A. "Even free radicals should follow some rules: A Guide to free radical research terminology and methodology." Free Radical Biology and Medicine, vol. 78, 2015, pp. 233-235. |
| Namba F, Go H, Murphy JA, La P, Yang G, Sengupta S, Fernando AP, Yohannes M, Biswas C, Wehrli SL, Dennery PA. "Expression level and subcellular localization of heme oxygenase-1 modulates its cytoprotective properties in response to lung injury: a mouse model." PLoS ONE, vol. 9, no. 3, 2014, pp. e90936. |
| Dennery PA. "Heme oxygenase in neonatal lung injury and repair." Antioxidants & redox signaling, vol. 21, no. 13, 2014, pp. 1881-92. |
| Michaelis KA, Agboke F, Liu T, Han K, Muthu M, Galambos C, Yang G, Dennery PA, Wright CJ. "IκBβ-mediated NF-κB activation confers protection against hyperoxic lung injury." American Journal of Respiratory Cell and Molecular Biology, vol. 50, no. 2, 2014, pp. 429-38. |
| Biswas, C., Shah, N., Muthu, M., La, P., Fernando, A. P., Sengupta, S., Yang, G., Dennery, P. A. "Nuclear Heme Oxygenase-1 (HO-1) Modulates Subcellular Distribution and Activation of Nrf2, Impacting Metabolic and Anti-oxidant Defenses." Journal of Biological Chemistry, vol. 289, no. 39, 2014, pp. 26882-26894. |
| Biswas C, Shah N, Muthu M, La P, Fernando AP, Sengupta S, Yang G, Dennery PA. "Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses." Journal of Biological Chemistry, vol. 289, no. 39, 2014, pp. 26882-94. |
| Yang G, Wright CJ, Hinson MD, Fernando AP, Sengupta S, Biswas C, La P, Dennery PA. "Oxidative stress and inflammation modulate Rev-erbα signaling in the neonatal lung and affect circadian rhythmicity." Antioxidants & redox signaling, vol. 21, no. 1, 2014, pp. 17-32. |
| Dennery PA. "Signaling function of heme oxygenase proteins." Antioxidants & redox signaling, vol. 20, no. 11, 2014, pp. 1743-53. |
| McKenna S, Michaelis KA, Agboke F, Liu T, Han K, Yang G, Dennery PA, Wright CJ. "Sustained hyperoxia-induced NF-κB activation improves survival and preserves lung development in neonatal mice." American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 306, no. 12, 2014, pp. L1078-89. |
| Yang G, Biswasa C, Lin QS, La P, Namba F, Zhuang T, Muthu M, Dennery PA. "Heme oxygenase-1 regulates postnatal lung repair after hyperoxia: role of β-catenin/hnRNPK signaling." Redox biology, vol. 1, 2013, pp. 234-43. |
| La P, Yang G, Dennery PA. "Mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation stabilizes ISCU protein: implications for iron metabolism." Journal of Biological Chemistry, vol. 288, no. 18, 2013, pp. 12901-9. |
| Dennery PA. "Evaluating the beneficial and detrimental effects of bile pigments in early and later life." Frontiers in Pharmacology, vol. 3, 2012, pp. 115. |
| Kalyanaraman B, Darley-Usmar V, Davies KJ, Dennery PA, Forman HJ, Grisham MB, Mann GE, Moore K, Roberts LJ 2nd, Ischiropoulos H. "Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations." Free Radical Biology and Medicine, vol. 52, no. 1, 2012, pp. 1-6. |
| Wright CJ, Agboke F, Muthu M, Michaelis KA, Mundy MA, La P, Yang G, Dennery PA. "Nuclear factor-κB (NF-κB) inhibitory protein IκBβ determines apoptotic cell death following exposure to oxidative stress." Journal of Biological Chemistry, vol. 287, no. 9, 2012, pp. 6230-9. |
| Dennery PA. "Introduction to the special issue on translational research involving oxidative stress." Free Radical Biology and Medicine, vol. 51, no. 5, 2011, pp. 923-4. |
| Yang G, Hinson MD, Bordner JE, Lin QS, Fernando AP, La P, Wright CJ, Dennery PA. "Silencing hyperoxia-induced C/EBPα in neonatal mice improves lung architecture via enhanced proliferation of alveolar epithelial cells." American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 301, no. 2, 2011, pp. L187-96. |
| Zhuang T, Zhang M, Zhang H, Dennery PA, Lin QS. "Disrupted postnatal lung development in heme oxygenase-1 deficient mice." Respiratory Research, vol. 11, 2010, pp. 142. |
| Wright CJ, Agboke F, Chen F, LA P, Yang G, Dennery PA. "NO inhibits hyperoxia-induced NF-κB activation in neonatal pulmonary microvascular endothelial cells." Pediatric Research, vol. 68, no. 6, 2010, pp. 484-9. |
| Dennery PA. "Oxidative stress in development: nature or nurture?." Free Radical Biology and Medicine, vol. 49, no. 7, 2010, pp. 1147-51. |
| Dennery PA. "Oxygen administration in the care of neonates: a double-edged sword." Chinese medical journal, vol. 123, no. 20, 2010, pp. 2938-42. |
| Kassovska-Bratinova S, Yang G, Igarashi K, Dennery PA. "Bach1 modulates heme oxygenase-1 expression in the neonatal mouse lung." Pediatric Research, vol. 65, no. 2, 2009, pp. 145-9. |
| Wright, C. J., Zhuang, T., La, P., Yang, G., Dennery, P. A. "Hyperoxia-induced NF- B activation occurs via a maturationally sensitive atypical pathway." AJP: Lung Cellular and Molecular Physiology, vol. 296, no. 3, 2009, pp. L296-L306. |
| Wright CJ, Dennery PA. "Manipulation of gene expression by oxygen: a primer from bedside to bench." Pediatric Research, vol. 66, no. 1, 2009, pp. 3-10. |
| La P, Fernando AP, Wang Z, Salahudeen A, Yang G, Lin Q, Wright CJ, Dennery PA. "Zinc protoporphyrin regulates cyclin D1 expression independent of heme oxygenase inhibition." Journal of Biological Chemistry, vol. 284, no. 52, 2009, pp. 36302-11. |
| Genel M, McCaffree MA, Hendricks K, Dennery PA, Hay WW Jr, Stanton B, Szilagyi PG, Jenkins RR. "A National Agenda for America's Children and Adolescents in 2008: recommendations from the 15th Annual Public Policy Plenary Symposium, annual meeting of the Pediatric Academic Societies, May 3, 2008." Pediatrics, vol. 122, no. 4, 2008, pp. 843-9. |
| Lin QS, Weis S, Yang G, Zhuang T, Abate A, Dennery PA. "Catalytic inactive heme oxygenase-1 protein regulates its own expression in oxidative stress." Free Radical Biology and Medicine, vol. 44, no. 5, 2008, pp. 847-55. |
| Kooli A, Kermorvant-Duchemin E, Sennlaub F, Bossolasco M, Hou X, Honoré JC, Dennery PA, Sapieha P, Varma D, Lachapelle P, Zhu T, Tremblay S, Hardy P, Jain K, Balazy M, Chemtob S. "trans-Arachidonic acids induce a heme oxygenase-dependent vasorelaxation of cerebral microvasculature." Free Radical Biology and Medicine, vol. 44, no. 5, 2008, pp. 815-25. |
| Dennery PA. "Effects of oxidative stress on embryonic development." Birth defects research. Part C, Embryo today : reviews, vol. 81, no. 3, 2007, pp. 155-62. |
| Lin Q, Weis S, Yang G, Weng YH, Helston R, Rish K, Smith A, Bordner J, Polte T, Gaunitz F, Dennery PA. "Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress." Journal of Biological Chemistry, vol. 282, no. 28, 2007, pp. 20621-33. |
| Dennery PA, Lorch S. "Neonatal blue-light phototherapy could increase the risk of dysplastic nevus development." Pediatrics, vol. 120, no. 1, 2007, pp. 247-8. |
| Alvira CM, Abate A, Yang G, Dennery PA, Rabinovitch M. "Nuclear factor-kappaB activation in neonatal mouse lung protects against lipopolysaccharide-induced inflammation." Am J Respir Crit Care Med, vol. 175, no. 8, 2007, pp. 805-15. |
| Als H, Behrman R, Checchia P, Denne S, Dennery P, Hall CB, Martin R, Panitch H, Schmidt B, Stevenson DK, Vila L. "Preemie abandonment? Multidisciplinary experts consider how to best meet preemies needs at "preterm infants: a collaborative approach to specialized care" roundtable." Modern healthcare, vol. 37, no. 23, 2007, pp. 17-24. |
| Goodman AI, Chander PN, Rezzani R, Schwartzman ML, Regan RF, Rodella L, Turkseven S, Lianos EA, Dennery PA, Abraham NG. "Heme oxygenase-2 deficiency contributes to diabetes-mediated increase in superoxide anion and renal dysfunction." Journal of the American Society of Nephrology, vol. 17, no. 4, 2006, pp. 1073-81. |
| Dennery PA. "Introduction to serial review on the role of oxidative stress in diabetes mellitus." Free Radical Biology and Medicine, vol. 40, no. 1, 2006, pp. 1-2. |
| Dennery PA. "Training and retaining of underrepresented minority physician scientists - an African-American perspective: NICHD AAP workshop on research in neonatal and perinatal medicine." Journal of perinatology : official journal of the California Perinatal Association, vol. 26 Suppl 2, 2006, pp. S46-8. |
| Abate A, Yang G, Wong RJ, Schroder H, Stevenson DK, Dennery PA. "Apigenin decreases hemin-mediated heme oxygenase-1 induction." Free Radical Biology and Medicine, vol. 39, no. 6, 2005, pp. 711-8. |
| Lee H, Pespeni M, Roux J, Dennery PA, Matthay MA, Pittet JF. "HO-1 induction restores c-AMP-dependent lung epithelial fluid transport following severe hemorrhage in rats." The FASEB Journal, vol. 19, no. 2, 2005, pp. 287-9. |
| Van Meurs KP, Cohen TL, Yang G, Somaschini M, Kuruma P, Dennery PA. "Inhaled NO and markers of oxidant injury in infants with respiratory failure." Journal of perinatology : official journal of the California Perinatal Association, vol. 25, no. 7, 2005, pp. 463-9. |
| Dennery PA. "Metalloporphyrins for the treatment of neonatal jaundice." Current Opinion in Pediatrics, vol. 17, no. 2, 2005, pp. 167-9. |
| Dennery PA. "Introduction to serial review on heme oxygenase in human disease." Free Radical Biology and Medicine, vol. 37, no. 8, 2004, pp. 1095-6. |
| Yang G, Abate A, George AG, Weng YH, Dennery PA. "Maturational differences in lung NF-kappaB activation and their role in tolerance to hyperoxia." Journal of Clinical Investigation, vol. 114, no. 5, 2004, pp. 669-78. |
| Dennery PA. "Role of redox in fetal development and neonatal diseases." Antioxidants & redox signaling, vol. 6, no. 1, 2004, pp. 147-53. |
| Browne SE, Roberts LJ 2nd, Dennery PA, Doctrow SR, Beal MF, Barlow C, Levine RL. "Treatment with a catalytic antioxidant corrects the neurobehavioral defect in ataxia-telangiectasia mice." Free Radical Biology and Medicine, vol. 36, no. 7, 2004, pp. 938-42. |
| Dennery PA, Lee CS, Ford BS, Weng YH, Yang G, Rodgers PA. "Developmental expression of heme oxygenase in the rat lung." Pediatric Research, vol. 53, no. 1, 2003, pp. 42-7. |
| Brown KE, Dennery PA, Ridnour LA, Fimmel CJ, Kladney RD, Brunt EM, Spitz DR. "Effect of iron overload and dietary fat on indices of oxidative stress and hepatic fibrogenesis in rats." Liver international : official journal of the International Association for the Study of the Liver, vol. 23, no. 4, 2003, pp. 232-42. |
| Oberle S, Abate A, Grosser N, Hemmerle A, Vreman HJ, Dennery PA, Schneider HT, Stalleicken D, Schröder H. "Endothelial protection by pentaerithrityl trinitrate: bilirubin and carbon monoxide as possible mediators." Experimental Biology and Medicine, vol. 228, no. 5, 2003, pp. 529-34. |
| Kreiser D, Kelly DK, Seidman DS, Stevenson DK, Baum M, Dennery PA. "Gestational pattern of heme oxygenase expression in the rat." Pediatric Research, vol. 54, no. 2, 2003, pp. 172-8. |
| Grosser N, Abate A, Oberle S, Vreman HJ, Dennery PA, Becker JC, Pohle T, Seidman DS, Schröder H. "Heme oxygenase-1 induction may explain the antioxidant profile of aspirin." Biochemical and Biophysical Research Communications, vol. 308, no. 4, 2003, pp. 956-60. |
| Weng YH, Yang G, Weiss S, Dennery PA. "Interaction between heme oxygenase-1 and -2 proteins." Journal of Biological Chemistry, vol. 278, no. 51, 2003, pp. 50999-1005. |
| Dennery PA. "Predicting neonatal brain injury: are we there yet?." Archives of Pediatrics & Adolescent Medicine, vol. 157, no. 12, 2003, pp. 1151-2. |
| Dennery PA, Visner G, Weng Yi, Nguyen X, Lu F, Zander D, Yang G. "Resistance to hyperoxia with heme oxygenase-1 disruption: role of iron." Free Radical Biology and Medicine, vol. 34, no. 1, 2003, pp. 124-33. |
| Yang G, Shegog ML, Dennery PA. "Effect of glutathione on lung activator protein-1 activation and heme oxygenase-1 induction in the immature rat." Pediatric Research, vol. 52, no. 1, 2002, pp. 34-9. |
| Oberle S, Abate A, Grosser N, Vreman HJ, Dennery PA, Schneider HT, Stalleicken D, Schröder H. "Heme oxygenase-1 induction may explain the antioxidant profile of pentaerythrityl trinitrate." Biochemical and Biophysical Research Communications, vol. 290, no. 5, 2002, pp. 1539-44. |
| Kreiser D, Nguyen X, Wong R, Seidman D, Stevenson D, Quan S, Abraham N, Dennery PA. "Heme oxygenase-1 modulates fetal growth in the rat." Laboratory investigation; a journal of technical methods and pathology, vol. 82, no. 6, 2002, pp. 687-92. |
| Dennery PA. "Pharmacological interventions for the treatment of neonatal jaundice." Seminars in neonatology : SN, vol. 7, no. 2, 2002, pp. 111-9. |
| Sabaawy HE, Zhang F, Nguyen X, ElHosseiny A, Nasjletti A, Schwartzman M, Dennery P, Kappas A, Abraham NG. "Human heme oxygenase-1 gene transfer lowers blood pressure and promotes growth in spontaneously hypertensive rats." Hypertension, vol. 38, no. 2, 2001, pp. 210-5. |
| Dennery PA. "Melatonin: the next panacea?." Pediatric Research, vol. 50, no. 6, 2001, pp. 680. |
| Wood, Alastair J.J., Dennery, Phyllis A., Seidman, Daniel S., Stevenson, David K. "Neonatal Hyperbilirubinemia." New England Journal of Medicine, vol. 344, no. 8, 2001, pp. 581-590. |
| Dennery PA, Seidman DS, Stevenson DK. "Neonatal hyperbilirubinemia." New England Journal of Medicine, vol. 344, no. 8, 2001, pp. 581-90. |
| Dennery PA, Weng YH, Stevenson DK, Yang G. "The biology of bilirubin production." Journal of perinatology : official journal of the California Perinatal Association, vol. 21 Suppl 1, 2001, pp. S17-20; discussion S35-9. |
| Stevenson DK, Dennery PA, Hintz SR. "Understanding newborn jaundice." Journal of perinatology : official journal of the California Perinatal Association, vol. 21 Suppl 1, 2001, pp. S21-4; discussion S35-9. |
| Yang G, Nguyen X, Ou J, Rekulapelli P, Stevenson DK, Dennery PA. "Unique effects of zinc protoporphyrin on HO-1 induction and apoptosis." Blood, vol. 97, no. 5, 2001, pp. 1306-13. |
| Ercal N, Neal R, Treeratphan P, Lutz PM, Hammond TC, Dennery PA, Spitz DR. "A role for oxidative stress in suppressing serum immunoglobulin levels in lead-exposed Fisher 344 rats." Archives of environmental contamination and toxicology, vol. 39, no. 2, 2000, pp. 251-6. |
| Stevenson DK, Vreman HJ, Wong RJ, Dennery PA, Contag CH. "Carbon monoxide detection and biological investigations." Transactions of the American Clinical and Climatological Association, vol. 111, 2000, pp. 61-75. |
| Baum M, Schiff E, Kreiser D, Dennery PA, Stevenson DK, Rosenthal T, Seidman DS. "End-tidal carbon monoxide measurements in women with pregnancy-induced hypertension and preeclampsia." American Journal of Obstetrics and Gynecology, vol. 183, no. 4, 2000, pp. 900-3. |
| Polte T, Abate A, Dennery PA, Schröder H. "Heme oxygenase-1 is a cGMP-inducible endothelial protein and mediates the cytoprotective action of nitric oxide." Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 20, no. 5, 2000, pp. 1209-15. |
| Weng YH, Tatarov A, Bartos BP, Contag CH, Dennery PA. "HO-1 expression in type II pneumocytes after transpulmonary gene delivery." American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 278, no. 6, 2000, pp. L1273-9. |
| Yang G, Madan A, Dennery PA. "Maturational differences in hyperoxic AP-1 activation in rat lung." American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 278, no. 2, 2000, pp. L393-8. |
| Dennery PA. "Regulation and role of heme oxygenase in oxidative injury." Current topics in cellular regulation, vol. 36, 2000, pp. 181-99. |
| Abate A, Yang G, Dennery PA, Oberle S, Schröder H. "Synergistic inhibition of cyclooxygenase-2 expression by vitamin E and aspirin." Free Radical Biology and Medicine, vol. 29, no. 11, 2000, pp. 1135-42. |
| Mireles LC, Lum MA, Dennery PA. "Antioxidant and cytotoxic effects of bilirubin on neonatal erythrocytes." Pediatric Research, vol. 45, no. 3, 1999, pp. 355-62. |
| Barlow C, Dennery PA, Shigenaga MK, Smith MA, Morrow JD, Roberts LJ 2nd, Wynshaw-Boris A, Levine RL. "Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs." Proceedings of the National Academy of Sciences, vol. 96, no. 17, 1999, pp. 9915-9. |
| Suttner DM, Sridhar K, Lee CS, Tomura T, Hansen TN, Dennery PA. "Protective effects of transient HO-1 overexpression on susceptibility to oxygen toxicity in lung cells." The American journal of physiology, vol. 276, no. 3 Pt 1, 1999, pp. L443-51. |
| Suttner DM, Dennery PA. "Reversal of HO-1 related cytoprotection with increased expression is due to reactive iron." The FASEB Journal, vol. 13, no. 13, 1999, pp. 1800-9. |
| Dennery PA, Spitz DR, Yang G, Tatarov A, Lee CS, Shegog ML, Poss KD. "Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2." Journal of Clinical Investigation, vol. 101, no. 5, 1998, pp. 1001-11. |
| Vreman HJ, Wong RJ, Sanesi CA, Dennery PA, Stevenson DK. "Simultaneous production of carbon monoxide and thiobarbituric acid reactive substances in rat tissue preparations by an iron-ascorbate system." Canadian journal of physiology and pharmacology, vol. 76, no. 12, 1998, pp. 1057-65. |
| Dennery PA, Sridhar KJ, Lee CS, Wong HE, Shokoohi V, Rodgers PA, Spitz DR. "Heme oxygenase-mediated resistance to oxygen toxicity in hamster fibroblasts." Journal of Biological Chemistry, vol. 272, no. 23, 1997, pp. 14937-42. |
| Contag CH, Spilman SD, Contag PR, Oshiro M, Eames B, Dennery P, Stevenson DK, Benaron DA. "Visualizing gene expression in living mammals using a bioluminescent reporter." Photochemistry and photobiology, vol. 66, no. 4, 1997, pp. 523-31. |
| Dennery PA, Wong HE, Sridhar KJ, Rodgers PA, Sim JE, Spitz DR. "Differences in basal and hyperoxia-associated HO expression in oxidant-resistant hamster fibroblasts." The American journal of physiology, vol. 271, no. 4 Pt 1, 1996, pp. L672-9. |
| Rodgers PA, Seidman DS, Wei PL, Dennery PA, Stevenson DK. "Duration of action and tissue distribution of zinc protoporphyrin in neonatal rats." Pediatric Research, vol. 39, no. 6, 1996, pp. 1041-9. |
| Tom DJ, Rodgers PA, Shokoohi V, Stevenson DK, Dennery PA. "Hepatic heme oxygenase is inducible in neonatal rats during the early postnatal period." Pediatric Research, vol. 40, no. 2, 1996, pp. 288-93. |
| Dennery PA, Rodgers PA, Lum MA, Jennings BC, Shokoohi V. "Hyperoxic regulation of lung heme oxygenase in neonatal rats." Pediatric Research, vol. 40, no. 6, 1996, pp. 815-21. |
| Dennery PA, Rodgers PA. "Ontogeny and developmental regulation of heme oxygenase." Journal of perinatology : official journal of the California Perinatal Association, vol. 16, no. 3 Pt 2, 1996, pp. S79-83. |
| Dennery PA, McDonagh AF, Spitz DR, Rodgers PA, Stevenson DK. "Hyperbilirubinemia results in reduced oxidative injury in neonatal Gunn rats exposed to hyperoxia." Free Radical Biology and Medicine, vol. 19, no. 4, 1995, pp. 395-404. |
| Dennery PA, Rhine WD, Stevenson DK. "Neonatal jaundice--what now?." Clinical Pediatrics, vol. 34, no. 2, 1995, pp. 103-7. |
| Rhine WD, Benitz WE, Dennery PA, Stevenson DK, Seidman DS. "Bilirubin measurements and long-term neurologic outcome." Pediatrics, vol. 94, no. 2 Pt 1, 1994, pp. 246. |
| Rodgers PA, Vreman HJ, Dennery PA, Stevenson DK. "Sources of carbon monoxide (CO) in biological systems and applications of CO detection technologies." Seminars in Perinatology, vol. 18, no. 1, 1994, pp. 2-10. |
| Wang TH, Johnston K, Hsieh CL, Dennery PA. "Terminal deletion of the long arm of chromosome 2 in a premature infant with karyotype: 46,XY,del(2)(q37)." American journal of medical genetics, vol. 49, no. 4, 1994, pp. 399-401. |
| Stevenson DK, Dennery PA. "Breath hydrogen excretion in infancy." The Journal of Pediatrics, vol. 122, no. 3, 1993, pp. 502-3. |
| Dennery, Phyllis A, Vreman, Hendrik J, Rodgers, Pamela A, Stevenson, David K. "Role of Lipid Peroxidation in Metalloporphyrin-Mediated Phototoxic Reactions in Neonatal Rats." Pediatric Research, vol. 33, no. 1, 1993, pp. 87-91. |
| Benaron DA, Yorgin PD, Lapuk S, Gibson R, Dennery PA. "Alkalemia in a newborn infant." The Journal of Pediatrics, vol. 120, no. 3, 1992, pp. 489-94. |
| Dennery PA, Conover PT, Kahn T, Jacobs G, Walsh-Sukys MC. "Premature twins with skin lesions and gastric outlet obstruction." The Journal of Pediatrics, vol. 120, no. 4 Pt 1, 1992, pp. 645-51. |
| Dennery PA, Walenga RW, Kramer CM, Alpert SE. "Prostaglandin E2 attenuates hyperoxia-induced injury in cultured rabbit tracheal epithelial cells." Pediatric Research, vol. 32, no. 1, 1992, pp. 87-91. |
| Dennery PA, Kramer CM, Alpert SE. "Effect of fatty acid profiles on the susceptibility of cultured rabbit tracheal epithelial cells to hyperoxic injury." American Journal of Respiratory Cell and Molecular Biology, vol. 3, no. 2, 1990, pp. 137-44. |
| Alpert SE, Kramer CM, Hayes MM, Dennery PA. "Morphologic injury and lipid peroxidation in monolayer cultures of rabbit tracheal epithelium exposed in vitro to ozone." Journal of toxicology and environmental health, vol. 30, no. 4, 1990, pp. 287-304. |
Dr. Dennery’s laboratory research is focused understanding mechansisms of neonatal lung injury and repair at the molecular level and using computational biology approaches. She is currently exploring how senescence and mitochondrial bioenergetics mediate responses to oxidative stress in the neonatal lung exposed to hyperoxia and exploring the developmental regulation of lung senescence, an important mediator of normal lung development and developing interventions to mitigate injury related senescence while preserving the important developmental senescence.
For over 35 years, I have focused understanding mechansisms of neonatal lung injury and repair as it pertains to bronchopulmonary dysplasia (BPD) a chronic lung disease of premature infants caused in part by oxygen and ventilatory support, with long-term respiratory consequences that can persist into adulthood. I developed an interest in understanding the mechanisms by which hyperoxic lung injury occurs in the newborns during my fellowship training in neonatal-perinatal medicine. After fellowship I took an academic position at Stanford University where I focused on understanding the role of heme oxygenase (HO-1), the rate-limiting enzyme in bilirubin production and a stress protein, in lung anti-oxidative defenses. My work identified developmental differences in the response of HO-1 to oxidative stress. While at Stanford I began collaborating with Rodney Levine at the National Institutes of Health and also with Douglas Spitz at Washington University. These collaborations enabled me to better determine oxidative stress signaling in rodent and cell model systems through molecular biology approaches. We defined the non-enzymatic function of HO-1 as a signaling molecule and described its migration from the smooth endoplasmic reticulum to the nucleus. I was then recruited to Children’s Hospital of Philadelphia/University of Pennsylvania as the Division Director of Neonatology. There I continued to explore how HO-1 mediates its functions in the lung and established a collaboration with Dr. Mitch Lazar at the University of Pennsylvania to explore circadian biology, in particular the nuclear receptor protein Rev-erb alpha, which has heme as a co-factor, and its relationship with HO-1 in mediating neonatal lung injury and repair. I assumed the leadership in the Department of Pediatrics at Brown University. At Brown, I began to explore the role of senescence in neonatal lung injury and discovered that macrophage senescence is a hallmark of BPD in an animal model using Single Cell Transcriptomics. I am currently also defining the developmental regulation of senescence in the neonatal lung in a comparative analysis of multiple species including non-human primates. This understanding will provide a foundation for developing targeted therapies to prevent or treat lung injury in premature infants.
T35 HL094308-06 12/2014 – TG Trainer NIH/NHLBI $208,910.00
Alpert Medical Student Summer 08/2019
Research Program (AMSSRP)
T32 HL134625 09/2016 - TG Trainer NIH
Brown Respiratory Research 08/2021
Training Program
R25 HL088992 07/2017 - TG Trainer NIH/NHLBI $679,397.00
Short-Term Training Program 06/2022
To Increase Diversity in Health-
Related Research
1UG1HD090901-01 09/21/2016 – PP Contact PI NIH/NIGMS $283,306.00
(ISPCTN/ECHO) 08/31/2020
Rhode Island Child Clinical
Trials Collaborative (RICCTC)
P20GM103652 06/01/2016- PP Mentor NIH/NIGMS $ 50,000.00 Ocean State Research Institute 05/31/2017
CPVB COBRE pilot project Yao (PI)
Dr Dennery's clinical interests are in neonatal jaundice, bronchopulmonary dysplasia and the long-term consequences of prematurity as well as on perinatal health disparities and the impact of race in Medicine.
Dennery PA: Series in Oxidative Stress Studies on Perinatal and Prenatal Disorders. Buonocore G, Saugstad O (co-eds) (eds.). Springer Science, 2013 (In Press).
Representative invited lectures:
"What's New with Necrotizing Enterocolitis". Invited speaker, OMI Satellite Symposium. Yerevan, Armenia, Sept 2009
Long Term Consequences of Prematurity". Invited speaker, OMI Satellite Symposium. Yerevan, Armenia, Sept 2009
"Oxygen: Poison or Panacea?" Invited Speaker, 5th Annual International Symposium of Neonatal Respiratory and Intensive Care. Guangzhou, China, Nov 2009
"Born Too Soon: Long Term Consequences of Prematurity", Visiting Professor, McGill University. Montreal, Canada, Dec 2009
"Oxidative Stress in Fetal Development". Topic Symposium. Pediatric Academic Societies meeting 2010. Vancouver, BC, May 2010
"Neonatal Hyperbilirubinemia in the 21st Century". Invited speaker, 15th Annual conference of the Egyptian Association of Neonatology (EAN). Cairo, Egypt, Jan 2011
"New Concepts in Necrotizing Enterocolitis". Invited speaker, 15th Annual conference of the Egyptian Association of Neonatology (EAN). Cairo, Egypt, Jan 2011
"Once a Premature Always a Premature: Long Term Consequences". Invited Speaker, 15th Annual conference of the Egyptian Association of Neonatology (EAN). Cairo, Egypt, Jan 2011
"What's New in Neonatal Nutrition". Invited speaker for the Workshop on Neonatal Nutrition. Cairo, Egypt, Jan 2011
"Heme Oxygenase-1 Regulates the Circadian Protein Rev-Erbα". International Perinatal Collegium Meeting. Amalfi, Italy, June 2011
"A Tale of Two Oxygens: How a Small Molecule Defined Neonatology". The Barry Smith Memorial Lecturer, Toronto Hospital for Sick Children. Ontario Canada, April 2012
"The Dual Nature of Oxygen in Neonates". Invited Speaker, The 48th Annual Congress of Japan Society of Perinatal and Neonatal Medicine. Saitama, Japan, July 2012
"Oxygen Use in the NICU: Good or Bad?" Invited speaker, Department of Pediatrics, Jikei University. Tokyo, Japan, July 2012
"Retinopathy of Prematurity". Lecturer, American Austrian Foundation, Neonatology Course. Salzburg, Austria, Oct 2012
"Neonatal Jaundice". Lecturer, American Austrian Foundation, Neonatology Course. Salzburg, Austria, Oct 2012
"The Late Preterm". Lecturer, American Austrian Foundation, Neonatology Course. Salzburg, Austria, Oct 2012
"Diseases of Oxidative Stress in the Newborn". International Symposium of Neonatal Medicine-Respiratory and Intensive Care. Guangzhou, China, Nov 2012
"Neonatology Past, Present and Future". Keynote Speaker, 4th International Symposium of Neonatal and Pediatric Respiratory and Intensive Care, Shijiazhuang. Hebei, China, Nov 2012
"Preventing and Treating Neonatal Hyperbilirubinemia" and "What About the Late Preterm Infant?" Invited Speaker, Bangkok International Neonatology Symposium. Bangkok, Thailand, Jan 2013
"How the Circadian Rhythm Alters and is Modulated by Oxidative Stress and Inflammation". Invited Speaker and Moderator, 23rd Biennial Meeting of the International Perinatal Collegiums. Banff, Alberta, Canada, July 2013
"Neonatal Jaundice". Visiting Professorship, University Klinik für Kinder-und Jugendheilkunde, Medizinische Universität Graz. Graz, Austria, July 2013
"Neonatology: Past, Present and Future". Invited Speaker, 2nd Latifa Hospital International Symposium on Maternal and Child Health. Dubai, United Arab Emirates, Nov 2013
"Maternal Prevention of prematurity and Child Health". Invited Speaker, 2nd Latifa Hospital International Symposium on Maternal and Child Health. Dubai, United Arab Emirates, Nov 2013
“Care of the VLBW preterm infant”. The 19th Annual Meeting of Chinese Pediatric Society. Chongqing China, Sept 2014
“Oxidative Stress in Newborns: the Role of Heme Oxygenase”, Athens, Greece, Dec 2014
“Oxidative Stress and Inflammation: From Bench to the NICU.” Update in Neonatology, Udine, Italy, March 2015
“Understanding BPD Etiology and Management.” Update in Neonatology, Udine, Italy, March 2015
“Using High-Fidelity Simulation in Resuscitation Education.” Invited Speaker KL International Neonatology Conference (KLINC), Kuala Lumpur, Malaysia, Nov, 2015
“Clock Genes: Bedtime in the NICU.” Invited Speaker, KL International Neonatology Conference (KLINC), Kuala Lumpur, Malaysia, Nov, 2015
“Breathing Problems in the Newborn,” Grand Rounds, St. Damien Hospital, Port-au Prince, Haiti, June 14, 2016
“The nuclear form of heme oxygenase-1 promotes glycolysis and restricts oxidative phosphorylation during oxidative stress,” World Mitochondria Society, Targeting Mitochondria World Congress, Berlin, Germany, October 2016
Finding Your Passion in Academic Medicine and Science: Paving the Road to Success.” Keynote Address for Office of Women in Medicine and Science (OWIMS) Annual Professional Development Conference, The Path to Your True North, Providence, RI , June 2016
Improving Child Health: a role for the community The Roselyn Payne Epps, M.D. Lecture in Pediatrics and Child Health, Howard University College of Medicine September 2016
| Year | Degree | Institution |
|---|---|---|
| 1984 | MD | Howard University |
| 1980 | BSc | McGill University |
| Fellow | Case Western Reserve University, Rainbow Babies and Childrens Hospital, neonatal-perinatal medicine | 1987-1990 | Cleveland , Ohio, USA |
1984 Grafton Rayner and Edna Spriggs Browne Award for Highest Cumulative Average
1994 Michael Oliver Dumas Prize from AOA for Highest Average
1997 Ross Young Investigator Award for Western Society for Pediatric Research
2000-2004 NIH Study Section, ATLX-4
2004 Elected to American Society for Clinical Investigation
2005 Elected to the Fellowship of the College of Physicians of Philadelphia
2005 Werner and Gertrude Henle Endowed Chair in Pediatrics, The Children's Hospital of Philadelphia
2006 Alfred Stengel Health System Champion Award, University of Pennsylvania School of Medicine
2007 President of Society for Pediatric Research
2009 Honorary Doctor of Science, Ursinus College
2011 Member, Secretary of Health and Human Services Advisory Committee on Infant Mortality
2012-13 Member, Institute of Medicine Committee to Review CTSA Programs
2013 Fellow of the Society for Free Radical Biology and Medicine
2013 Elected to the Institute of Medicine
2013 Mentor of the Year, Eastern Society for Pediatric Research
2014 Recipient Marion Spencer Fay Award
2015 Elected to the Association of American Physicians
2016 Elected to the American Clinical and Climatologic Association
2016 Speaker, Kristine Sanberg Knisely Memorial Lectureship
Speaker, Provost Faculty Lecture Series, Building Intellectual Community
2016 Master of Arts Ad Eundem Brown University
2017 Howard University College of Medicine Roslyn Payne Epps, MD Lecture, Washington, DC
2017 Best Docs in America
2017 Induction into the American Clinical Climatologic Association
2021 Hope Award, Graham's Foundation
2023 American Thoracic Society Fellow
2023 Keynote speaker, Gordon Conference The IGF and Insulin System: From Basic Science to Clinical Translation and New Technologies
2023 Keynote speaker, Symposium in honor of Daret St Clair University of Kentucky
2024 Keynote speaker, Grover F. Powers, MD, Memorial Lectureship , Yale University
2025-2026 Co-Chair, National Academies of Science, Engineering, and Medicine Committee on Strategies to Enhance Pediatric Health Research Funded by NIH
| Name | Title |
|---|---|
| Bath, Kevin | Associate Professor of Cognitive, Linguistic and Psychological Sciences |
| Brayboy, Lynae | Assistant Professor of Obstetrics and Gynecology (Research), Assistant Professor of Molecular Biology, Cell Biology and Biochemistry (Research) |
| Chun, Thomas | Professor of Pediatrics, Professor of Emergency Medicine |
| Elias, Jack | Warren Alpert Foundation Professor of Translational Science, Professor of Molecular Biology, Cell Biology and Biochemistry, Professor of Medicine |
| Laptook, Abbot | Professor Emeritus of Pediatrics |
| Morrow, Eric | Mencoff Family Professor of Biology, Professor of Brain Science, Professor of Neuroscience, Professor of Psychiatry and Human Behavior |
| Tyrka, Audrey | Mary E. Zucker Professor of Psychiatry and Human Behavior, Professor of Psychiatry and Human Behavior, Chair of Psychiatry and Human Behavior |
Professor of Pediatrics
Professor of Molecular Biology, Cell Biology and Biochemistry
Sylvia Kay Hassenfeld Professor of Pediatrics
Chair, Department of Pediatrics
Warren Alpert Medical School of Brown University
Medical Director and Pediatrician-in-Chief
Department of Pediatrics, Rhode Island Hospital/Hasbro Children’s Hospital
| Medical Licence | State of Rhode Island & Providence Plantations | 2015- | |
| Medical Doctor | Howard University | 1984- | |
| Internship and Residency | George Washington University, Department of Pediatrics | 1984-1987 |
