Dr. Ece Uzun is an Associate Professor of Pathology and Laboratory Medicine, and Founding Director of Clinical Bioinformatics at Brown University Health. She is the Deputy Director of Brown Center for Clinical Cancer Informatics and Data Science (CCIDS). She is also a member of Brown University Center for Computational Molecular Biology (CCMB), Brown University Data Science Institute and Brown University Center for Biomedical Informatics (BCBI). She received B.S in Chemical Engineering at Istanbul Technical University and M.S. in Biological Sciences and Bioengineering at Sabanci University in Istanbul, Turkey. She completed her PhD in Chemical Engineering at Northeastern University, Boston, MA. During her PhD, she studied mathematical modeling of drug delivery systems. During her postdoctoral studies at Brown University, she worked on bioinformatics and computational genetics focusing on neurodevelopmental disorders and autism.
As Director of Clinical Bioinformatics at Molecular Pathology, Dr. Uzun oversees the analysis of next-generation sequencing-based molecular diagnostic testing and the integration of test results into the electronic health records to support patient care. In addition to her clinical bioinformatics work, Dr. Uzun leads a research group focusing on development of multi-modal deep learning based predictive models in cancer and complex disorders using clinical, genomic and whole-slide image data from patients. She also studies protein-protein interaction networks in cancer for drug repurposing using genomic and spatial transcriptomics data. Her research group has also developed novel genomic variation detection algorithms. She is the inaugural Editor-in-Chief in JMIR Bioinformatics and Biotechnology journal. She is the Chair of the American Medical Informatics Association (AMIA) Genomics and Translational Bioinformatics Working Group and co-Chair of the Women in AMIA (WIA) Steering Committee.
Research Group website:
Translational Bioinformatics Lab
DNA markers in low-IQ autism suggest heredity
Translational Bioinformatics Lab
