Dr. Hwamee Oh is an Associate Professor in the Departments of Psychiatry and Human Behavior (primary) and Cognitive and Psychological Sciences (secondary) and is also affiliated with Carney Institute for Brain Science. Dr. Oh received her PhD in Biopsychology (with concentration in Human Cognitive Neuroscience) at the State University of New York at Stony Brook. In her postdoctoral training in Dr. William Jagust’s laboratory in Helen Wills Neuroscience Institute at UC-Berkeley, she studied cognitive, structural, and functional alterations in preclinical older adults with β-amyloid deposition, a pathological hallmark of Alzheimer’s disease, using amyloid PET, structural MRI, fMRI and neuropsychological tests. Prior to Brown, Dr. Oh was an Assistant Professor at Columbia University (2014-2017) and a Research Assistant Professor at SUNY-Stony Brook (2017-2019). At Brown, Dr. Oh extends her research on cognitive and neural changes due to normal aging and Alzheimer's disease pathology and individual difference factors contributing to the brain aging and cognition relationship using multimodality neuroimaging methods including PET and structural and functional MRI.
| Matthew D Howe, Megan R Caruso, Masood Manoochehri, Zachary J Kunicki, Sheina Emrani, James L Rudolph, Edward D Huey, Stephen P Salloway, Hwamee Oh; Alzheimer's Disease Neuroimaging Initiative. ".Utility of cerebrovascular imaging biomarkers to detect cerebral amyloidosis." Alzheimer's & Dementia, 2024. |
| Nelly Joseph-Mathurin, Rebecca L Feldman, Ruijin Lu, Zahra Shirzadi, Carmen Toomer, Junie R Saint Clair, Yinjiao Ma, Nicole S McKay, Jeremy F Strain, Collin Kilgore, Karl A Friedrichsen, Charles D Chen, Brian A Gordon, Gengsheng Chen, Russ C Hornbeck, Parinaz Massoumzadeh, Austin A McCullough, Qing Wang, Yan Li, Guoqiao Wang, Sarah J Keefe, Stephanie A Schultz, Carlos Cruchaga, Gregory M Preboske, Clifford R Jack Jr, Jorge J Llibre-Guerra, Ricardo F Allegri, Beau M Ances, Sarah B Berman, William S Brooks, David M Cash, Gregory S Day, Nick C Fox, Michael Fulham, Bernardino Ghetti, Keith A Johnson, Mathias Jucker, William E Klunk, Christian la Fougère, Johannes Levin, Yoshiki Niimi , Hwamee Oh, Richard J Perrin, Gerald Reischl, John M Ringman, Andrew J Saykin, Peter R Schofield, Yi Su, Charlene Supnet-Bell, Jonathan Vöglein, Igor Yakushev, Adam M Brickman, John C Morris, Eric McDade, Chengjie Xiong, Randall J Bateman, Jasmeer P Chhatwal, Tammie L S Benzinger; Dominantly Inherited Alzheimer Network. "Presenilin-1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage." Alzheimer's & Dementia, vol. 20, no. 4, 2024, pp. 2680-2697. |
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Theresa M. Harrison, Tyler Ward, Jacinda Taggett, Pauline Maillard, Samuel N Lockhart, Youngkyoo Jung, Laura C. Lovato, Robert Koeppe, William J. Jagust, Danielle Harvey, Joseph Masdeu, Hwamee Oh, Darren R. Gitelman, Neelum Aggarwal, Mark Espeland, Jo Cleveland, Rachel Whitmer, Sarah Farias, Stephen Salloway, Valory Pavlik, Melissa Yu, Christine Tangney, Heather Snyder, Maria Carrillo, Laura D. Baker, Prashanthi Vemuri, Charles DeCarli, Susan M. Landau, for the U.S. POINTER Study Group.
"The POINTER Imaging baseline cohort: Associations between multimodal neuroimaging biomarkers, cardiovascular health and cognition." Alzheimer's & Dementia, 2024.
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| Rahmani F, Brier MR, Gordon BA, McKay N, Flores S, Keefe S, Hornbeck R, Ances B, Joseph-Mathurin N, Xiong C, Wang G, Raji CA, Libre-Guerra JJ, Perrin RJ, McDade E, Daniels A, Karch C, Day GS, Brickman AM, Fulham M, Jack CR Jr, la La Fougère C, Reischl G, Schofield PR, Oh H, Levin J, Vöglein J, Cash DM, Yakushev I, Ikeuchi T, Klunk WE, Morris JC, Bateman RJ, Benzinger TLS, Dominantly Inherited Alzheimer Network (DIAN). "T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer disease." Human Brain Mapping, 2023. |
| Jenna K. Blujus and Hwamee Oh. "Denoising Approach Affects Diagnostic Differences in Brain Connectivity across the Alzheimer’s Disease Continuum." BioRxiv, 2022. |
| Hwamee Oh. "Extraversion is associated with lower brain amyloid deposition in cognitively normal older adults." Frontiers in Aging Neuroscience, 2022. |
| Jenna K. Blujus, Michael W. Cole, Elena K. Festa, Stephen L. Buka, Stephen P. Salloway, William C. Heindel, Hwamee Oh, the Alzheimer’s Disease Neuroimaging Initiative. "Functional Redundancy of the Posterior Hippocampi, but not Anterior Hippocampi or Left Frontal Cortex, is Disrupted in Pathological Brain Aging." BioRxiv, 2022. |
| Theresa M. Harrison, Tyler J. Ward, Alice Murphy, Suzanne L. Baker, Pablo A. Dominguez, Robert Koeppe, Prashanthi Vemuri, Samuel N. Lockhart, Youngkyoo Jung, Danielle J. Harvey, Laura Lovato, Arthur W. Toga, Joseph Masdeu, Hwamee Oh, Darren R. Gitelman, Neelum Aggarwal, Maria Carillo, Laura D. Baker, Charles DeCarli, William J. Jagust, Susan M. Landau, for the U.S. POINTER Study Group. "Optimizing quantification of MK6240 tau PET in unimpaired older adults." NeuroImage, 2022. |
| Luckett PH, et al. "Modeling autosomal dominant Alzheimer's disease with machine learning." Alzheimer's & Dementia, 2021. |
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Alber J, Popescu D, Thompson LI, Tonini G-M, Arthur E, Oh H, Correia S, Salloway SP, Lee AK.
"Safety and tolerability of APOE genotyping and disclosure in cognitively normal volunteers from the Butler Alzheimer’s Prevention Registry." the Journal of Geriatric Psychiatry and Neurology, 2021.
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| Dincer A, Gordon BA, Hari-Raj A, Keefe SJ, Flores S, McKay NS, Paulick AM, Shady Lewis KE, Feldman RL, Hornbeck RC, Allegri R, Ances BM, Berman SB, Brickman AM, Brooks WS, Cash DM, Chhatwal JP, Farlow MR, la Fougère C, Fox NC, Fulham MJ, Jack CR Jr, Joseph-Mathurin N, Karch CM, Lee A, Levin J, Masters CL, McDade EM, Oh H, Perrin RJ, Raji C, Salloway SP, Schofield PR, Su Y, Villemagne VL, Wang Q, Weiner MW, Xiong C, Yakushev I, Morris JC, Bateman RJ, L S Benzinger T, Dominantly Inherited Alzheimer Network DIAN. "Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease." NeuroImage. Clinical, vol. 28, 2020, pp. 102491. |
| Finsterwalder S, et al. "Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients." Alzheimer's & Dementia, vol. 16, no. 11, 2020, pp. 1504-1514. |
| Oh H, Razlighi QR, Stern Y. "Multiple pathways of reserve simultaneously present in cognitively normal older adults." Neurology, vol. 90, no. 3, 2018, pp. e197-e205. |
| Razlighi QR, Oh H, Habeck C, O'Shea D, Gazes E, Eich T, Parker DB, Lee S, Stern Y. "Dynamic Patterns of Brain Structure-Behavior Correlation Across the Lifespan." Cerebral Cortex, vol. 27, no. 7, 2017, pp. 3586-3599. |
| Oh H, Madison C, Baker S, Rabinovici G, Jagust W. "Dynamic relationships between age, amyloid-β deposition, and glucose metabolism link to the regional vulnerability to Alzheimer's disease." Brain, vol. 139, no. Pt 8, 2016, pp. 2275-89. |
| Eich TS, Parker D, Liu D, Oh H, Razlighi Q, Gazes Y, Habeck C, Stern Y. "Functional brain and age-related changes associated with congruency in task switching." Neuropsychologia, vol. 91, 2016, pp. 211-221. |
| Oh H, Steffener J, Razlighi QR, Habeck C, Stern Y. "β-Amyloid Deposition Is Associated with Decreased Right Prefrontal Activation during Task Switching among Cognitively Normal Elderly." Journal of Neuroscience, vol. 36, no. 6, 2016, pp. 1962-70. |
| Oh H, Steffener J, Razlighi QR, Habeck C, Liu D, Gazes Y, Janicki S, Stern Y. "Aβ-related hyperactivation in frontoparietal control regions in cognitively normal elderly." Neurobiology of aging, vol. 36, no. 12, 2015, pp. 3247-3254. |
| Oh H, Madison C, Villeneuve S, Markley C, Jagust WJ. "Association of gray matter atrophy with age, β-amyloid, and cognition in aging." Cerebral Cortex, vol. 24, no. 6, 2014, pp. 1609-18. |
| Oh H, Habeck C, Madison C, Jagust W. "Covarying alterations in Aβ deposition, glucose metabolism, and gray matter volume in cognitively normal elderly." Human Brain Mapping, vol. 35, no. 1, 2014, pp. 297-308. |
| Ossenkoppele R, Madison C, Oh H, Wirth M, van Berckel BN, Jagust WJ. "Is verbal episodic memory in elderly with amyloid deposits preserved through altered neuronal function?." Cerebral Cortex, vol. 24, no. 8, 2014, pp. 2210-8. |
| Elman JA, Oh H, Madison CM, Baker SL, Vogel JW, Marks SM, Crowley S, O'Neil JP, Jagust WJ. "Neural compensation in older people with brain amyloid-β deposition." Nature Neuroscience, vol. 17, no. 10, 2014, pp. 1316-8. |
| Wirth M, Madison CM, Rabinovici GD, Oh H, Landau SM, Jagust WJ. "Alzheimer's disease neurodegenerative biomarkers are associated with decreased cognitive function but not β-amyloid in cognitively normal older individuals." Journal of Neuroscience, vol. 33, no. 13, 2013, pp. 5553-63. |
| Wirth M, Villeneuve S, Haase CM, Madison CM, Oh H, Landau SM, Rabinovici GD, Jagust WJ. "Associations between Alzheimer disease biomarkers, neurodegeneration, and cognition in cognitively normal older people." JAMA neurology, vol. 70, no. 12, 2013, pp. 1512-9. |
| Oh H, Jagust WJ. "Frontotemporal network connectivity during memory encoding is increased with aging and disrupted by beta-amyloid." Journal of Neuroscience, vol. 33, no. 47, 2013, pp. 18425-37. |
| Hedden T, Oh H, Younger AP, Patel TA. "Meta-analysis of amyloid-cognition relations in cognitively normal older adults." Neurology, vol. 80, no. 14, 2013, pp. 1341-8. |
| Han X, Berg AC, Oh H, Samaras D, Leung HC. "Multi-voxel pattern analysis of selective representation of visual working memory in ventral temporal and occipital regions." NeuroImage, vol. 73, 2013, pp. 8-15. |
| Wirth M, Oh H, Mormino EC, Markley C, Landau SM, Jagust WJ. "The effect of amyloid β on cognitive decline is modulated by neural integrity in cognitively normal elderly." Alzheimer's & Dementia, vol. 9, no. 6, 2013, pp. 687-698.e1. |
| Landau SM, Marks SM, Mormino EC, Rabinovici GD, Oh H, O'Neil JP, Wilson RS, Jagust WJ. "Association of lifetime cognitive engagement and low β-amyloid deposition." Archives of Neurology, vol. 69, no. 5, 2012, pp. 623-29. |
| Oh H, Madison C, Haight TJ, Markley C, Jagust WJ. "Effects of age and β-amyloid on cognitive changes in normal elderly people." Neurobiology of aging, vol. 33, no. 12, 2012, pp. 2746-55. |
| Oh H, Mormino EC, Madison C, Hayenga A, Smiljic A, Jagust WJ. "β-Amyloid affects frontal and posterior brain networks in normal aging." NeuroImage, vol. 54, no. 3, 2011, pp. 1887-95. |
| Oh H, Leung HC. "Specific and nonspecific neural activity during selective processing of visual representations in working memory." Journal of Cognitive Neuroscience, vol. 22, no. 2, 2010, pp. 292-306. |
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Yang, H., Oh, H., Leung, H.C., & Zelinsky, G.J.
"An effect of WM load on visual search guidance: Evidence from eye movements and functional brain imaging." Journal of Vision, 2008.
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| Leung HC, Oh H, Ferri J, Yi Y. "Load response functions in the human spatial working memory circuit during location memory updating." NeuroImage, vol. 35, no. 1, 2007, pp. 368-77. |
NIH/NIA R01-AG068990 Developing novel cognitive and neuroimaging markers of early Alzheimer's disease pathologies
Role: Principal Investigator
Project duration: 09/15/2020-5/31/2025
NIH/NIA R01-AG073267 Longitudinal multi-center head-to-head harmonization of tau PET tracers
Role: Subaward PI
Project duration: 09/01/2021 – 05/31/2026
NIH/NIA R01-AG069265 Mechanisms of risk and resilience to age-related cognitive decline: A 60-year prospective prenatal cohort
Role: Co-Investigator
Project duration: 09/15/2020-4/30/2025
NIH/NIA R01-AG075511 High-dimensional Modeling of PET for radiomic Biomarker Discovery
Role: Co-Investigator
Project duration: 09/01/2022 – 05/31/2027
NIH/NIA RF1 MH130415 Secondary analysis of resting state MEG data using the Human Neocortical Neurosolver software tool for cellular and circuit-level interpretation
Role: Co-Investigator
Project duration: 08/01/2022 – 07/31/2025
COBRE-Central Nervous System Function Pilot Award (NIGMS and Carney Institute)
Role: Pilot Project Leader
Project duration: 10/01/2019-7/31/2023
NIH/NIA R01-AG062689 US POINTER Neuroimaging Ancillary Study
Role: Site Imaging PI (Rhode Island/Butler)
Project duration: 08/01/2019-3/31/2024
Alzheimer’s Association 2019 Part the Cloud: Repurposing nucleoside reverse transcriptase inhibitors for treatment of AD
Role: Co-Investigator
Project duration: 10/01/2020 – 3/31/2024
Brown University Carney Institute Center for Alzheimer's Disease Research Grant
Role: Co-Investigator
Project duration: 09/30/2021 – 5/31/2026
| Year | Degree | Institution |
|---|---|---|
| 2009 | PhD | State University of New York at Stony Brook |
| 2005 | MA | State University of New York at Stony Brook |
| 1998 | MA | Ewha Womens University |
| 1994 | BA | Ewha Womens University |
| Postdoctoral Fellow | UC-Berkeley | 2009-2014 | Berkeley, CA, USA |
NIH, Clinical Neuroscience and Neurodegeneration (CNN) Study Section, Invited Standing Member, Center for Scientific Review. 2023-2027
NIH Early Career Reviewer Program, Center for Scientific Review. 2016.
Travel Scholarship Award, Alzheimer’s Association International Conference, Toronto, Canada, 2016.
Travel Scholarship Award, Alzheimer’s Imaging Consortium, preconference of Alzheimer’s Association International Conference, Toronto, Canada, 2016.
The de Leon Prize in Neuroimaging: New Investigator Award, Alzheimer’s Association International Conference, Alzheimer’s Imaging Consortium, Copenhagen, Denmark. 2014.
Travel Scholarship Award, Human Amyloid Imaging Conference, Miami, FL. 2014.
Travel Scholarship Award, Alzheimer’s Association International Conference, Boston, MA. 2013.
Travel Scholarship Award, Alzheimer’s Imaging Consortium, preconference of Alzheimer’s Association International Conference, Boston, MA. 2013.
Travel Scholarship Award, Human Amyloid Imaging Conference, Miami, FL. 2012.
Alzheimer’s Association Award for Excellence in Research on Alzheimer’s and Related Disorders, 1st place, Alzheimer’s Association Symposium, Stanford University, 2011.
UCLA Advanced Neuroimaging Summer School Fellowship, UCLA, 2009.
Emeritus Faculty Dissertation Award, Department of Psychology, SUNY-Stony Brook, 2008.
Departmental Alumni Summer Research Fellowship, 1st prize, SUNY-Stony Brook, 2005.
Graduate Presidential Fellowship for Outstanding Entering Students, SUNY-Stony Brook, 2002.
| Name | Title |
|---|---|
| Buka, Stephen | Professor of Epidemiology |
| Carskadon, Mary | Adjunct Professor of Cognitive and Psychological Sciences, Professor of Psychiatry and Human Behavior |
| Crawford, Lorin | Distinguished Senior Fellow in Biostatistics |
| Dibble, Elizabeth | Associate Professor of Diagnostic Imaging |
| Eloyan, Ani | Associate Professor of Biostatistics, Vice Chair of Biostatistics |
| Festa, Elena | Senior Lecturer in Cognitive and Psychological Sciences |
| Greenberg, Benjamin | Professor of Psychiatry and Human Behavior |
| Heindel, William | Professor of Cognitive and Psychological Sciences |
| Jones, Rich | Professor of Psychiatry and Human Behavior, Professor of Neurology |
| Jones, Stephanie | Professor of Neuroscience |
| Lee, Athene | Associate Professor of Psychiatry and Human Behavior, Clinician Educator |
| McLaughlin, Nicole | Associate Professor of Psychiatry and Human Behavior |
| Nassar, Matt | Assistant Professor of Neuroscience |
| Salloway, Stephen | Professor of Psychiatry and Human Behavior, Professor of Neurology |
| Sedivy, John | Hermon C. Bumpus Professor of Biology, Associate Dean and Director, Center for the Biology of Aging |
| Serre, Thomas | Thomas J. Watson, Sr. Professor of Science and Professor of Computer Science., Professor of Computer Science |
| Song, Joo-Hyun | Associate Professor of Cognitive and Psychological Sciences |
| Thompson, Louisa | Assistant Professor of Psychiatry and Human Behavior |
The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART)
Society for Neuroscience
Cognitive Neuroscience Society
Organization for Human Brain Mapping
International Society for Magnetic Resonance in Medicine (ISMRM)
Psychonomic Society
Women in Cognitive Science
SPARK Society
| Associate Professor of Psychiatry and Human Behavior. Brown University, 2022-Present |
| Associate Professor of Cognitive and Psychological Sciences (Secondary Appointment). Department of Cognitive, Linguistic, and Psychological Sciences, 2022-Present |
| Faculty Trainer. Department of Neuroscience, 2022-2024 |
| Data and Safety Monitoring Board (DSMB) Member. Massachusetts General Hospital/Harvard Medical School, 2021-Present |
| Faculty Preceptor, Brown T32 Postdoctoral Training Program in Computational Psychiatry. Brown University, 2021-Present |
| Faculty Preceptor, Brown T32 Graduate Training Program in the Interdisciplinary Training in Computational, Cognitive, and Systems Neuroscience (ICoN). Brown University , 2021-Present |
| Director of Imaging Research, Memory and Aging Program. Butler Hospital, 2019-2023 |
| Cognitive Neuroscientist. Butler Hospital, 2019-2023 |
| Faculty-Affiliate in Carney Institute for Brain Science. Carney Institute for Brain Science, 2019-Present |
