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Dubay, R., Fiering, J., Darling, E. M.
"Effect of elastic modulus on inertial displacement of cell-like particles in microchannels." Biomicrofluidics, vol. 14, no. 4, 2020, pp. 044110.
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Sadick, Jessica S., Crawford, Lorin A., Cramer, Harry C., Franck, Christian, Liddelow, Shane A., Darling, Eric M.
"Generating Cell Type-Specific Protein Signatures from Non-symptomatic and Diseased Tissues." Annals of Biomedical Engineering, 2020.
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Sarnik, Sylvia A., Sutermaster, Bryan A., Darling, Eric M.
"Mass‐Added
Density Modulation for Sorting Cells Based on Differential Surface Protein Levels." Cytometry Part A, 2020.
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Sutermaster BA, Darling EM.
"Considerations for high-yield, high-throughput cell enrichment: fluorescence versus magnetic sorting." Scientific reports, vol. 9, no. 1, 2019, pp. 227.
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Shah MK, Leary EA, Darling EM.
"Integration of hyper-compliant microparticles into a 3D melanoma tumor model." Journal of Biomechanics, vol. 82, 2019, pp. 46-53.
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Meyer, Kristin C., Labriola, Nicholas R., Darling, Eric M., Kaehr, Bryan.
"Shape‐Preserved Transformation of Biological Cells into Synthetic Hydrogel Microparticles." Advanced Biosystems, vol. 3, no. 4, 2019, pp. 1800285.
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Labriola NR, Sadick JS, Morgan JR, Mathiowitz E, Darling EM.
"Cell Mimicking Microparticles Influence the Organization, Growth, and Mechanophenotype of Stem Cell Spheroids." Annals of Biomedical Engineering, vol. 46, no. 8, 2018, pp. 1146-1159.
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Labriola, Nicholas R., Azagury, Aharon, Gutierrez, Robert, Mathiowitz, Edith, Darling, Eric M.
"Concise Review: Fabrication, Customization, and Application of Cell Mimicking Microparticles in Stem Cell Science." STEM CELLS Translational Medicine, 2018.
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Clyne, Alisa Morss, Marcolongo, Michele, Darling, Eric M., Chahine, Nadeen O.
"Correction to: Translating Mechanobiology to the Clinic: A Panel Discussion from the 2018 CMBE Conference." Cellular and Molecular Bioengineering, vol. 12, no. 1, 2018, pp. 131-131.
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González-Cruz RD, Sadick JS, Fonseca VC, Darling EM.
"Nuclear Lamin Protein C Is Linked to Lineage-Specific, Whole-Cell Mechanical Properties." Cellular and Molecular Bioengineering, vol. 11, no. 2, 2018, pp. 131-142.
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Parsons AM, Ciombor DM, Liu PY, Darling EM.
"Regenerative Potential and Inflammation-Induced Secretion Profile of Human Adipose-Derived Stromal Vascular Cells Are Influenced by Donor Variability and Prior Breast Cancer Diagnosis." Stem Cell Reviews and Reports, vol. 14, no. 4, 2018, pp. 546-557.
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Azagury, Aharon, Fonseca, Vera C., Cho, Daniel Y., Perez-Rogers, James, Baker, Christopher M., Steranka, Elaine, Goldenshtein, Victoria, Calvao, Dominick, Darling, Eric M., Mathiowitz, Edith.
"Single Step Double-walled Nanoencapsulation (SSDN)." Journal of Controlled Release, vol. 280, 2018, pp. 11-19.
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Dempsey ME, Marble HD, Shen TL, Fawzi NL, Darling EM.
"Synthesis and Characterization of a Magnetically Active 19F Molecular Beacon." Bioconjugate Chem., vol. 29, no. 2, 2018, pp. 335-342.
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González-Cruz RD, Dahl KN, Darling EM.
"The Emerging Role of Lamin C as an Important LMNA Isoform in Mechanophenotype." Frontiers in Cell and Developmental Biology, vol. 6, 2018, pp. 151.
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Clyne, Alisa Morss, Marcolongo, Michele, Darling, Eric M., Chahine, Nadeen O.
"Translating Mechanobiology to the Clinic: a panel discussion from the 2018 CMBE Conference." Cellular and Molecular Bioengineering, vol. 11, no. 6, 2018, pp. 531-535.
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Athanasiou KA, Darling EM, Duraine GD, Hu JC, Reddi AH.
Articular Cartilage, Second Edition. CRC Press, 2017.
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Clyne, Alisa Morss, Darling, Eric M., Chahine, Nadeen O.
"Discovering the Keys: Transformative and Translational Mechanobiology." Cellular and Molecular Bioengineering, vol. 10, no. 4, 2017, pp. 273-274.
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Labriola, Nicholas R., Mathiowitz, Edith, Darling, Eric M.
"Fabricating polyacrylamide microbeads by inverse emulsification to mimic the size and elasticity of living cells." Biomater. Sci., vol. 5, no. 1, 2017, pp. 41-45.
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Xia Y, Darling EM, Herzog W.
"Functional properties of chondrocytes and articular cartilage using optical imaging to scanning probe microscopy." Journal of Orthopaedic Research, vol. 36, no. 2, 2017, pp. 620-631.
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Shah MK, Garcia-Pak IH, Darling EM.
"Influence of Inherent Mechanophenotype on Competitive Cellular Adherence." Annals of Biomedical Engineering, 2017.
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Sadick, Jessica S., Darling, Eric M.
"Processing fixed and stored adipose-derived stem cells for quantitative protein array assays." BioTechniques, vol. 63, no. 6, 2017.
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López-Fagundo C, Livi LL, Ramchal T, Darling EM, Hoffman-Kim D.
"A biomimetic synthetic feeder layer supports the proliferation and self-renewal of mouse embryonic stem cells." Acta Biomaterialia, vol. 39, 2016, pp. 55-64.
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Chen Y, Cossman J, Jayasuriya CT, Li X, Guan Y, Fonseca V, Yang K, Charbonneau C, Yu H, Kanbe K, Ma P, Darling E, Chen Q.
"Deficient Mechanical Activation of Anabolic Transcripts and Post-Traumatic Cartilage Degeneration in Matrilin-1 Knockout Mice." PLoS ONE, vol. 11, no. 6, 2016, pp. e0156676.
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Beane OS, Darling LE, Fonseca VC, Darling EM.
"Disparate Response to Methotrexate in Stem Versus Non-Stem Cells." Stem cell reviews and reports, vol. 12, no. 3, 2016, pp. 340-51.
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Sadick JS, Boutin ME, Hoffman-Kim D, Darling EM.
"Protein characterization of intracellular target-sorted, formalin-fixed cell subpopulations." Scientific reports, vol. 6, 2016, pp. 33999.
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Darling EM, Di Carlo D.
"High-Throughput Assessment of Cellular Mechanical Properties." Annual Review of Biomedical Engineering, vol. 17, 2015, pp. 35-62.
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Labriola, Nicholas R., Darling, Eric M.
"Temporal heterogeneity in single-cell gene expression and mechanical properties during adipogenic differentiation." Journal of Biomechanics, vol. 48, no. 6, 2015, pp. 1058-1066.
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Dingle, Yu-Ting L., Boutin, Molly E., Chirila, Anda M., Livi, Liane L., Labriola, Nicholas R., Jakubek, Lorin M., Morgan, Jeffrey R., Darling, Eric M., Kauer, Julie A., Hoffman-Kim, Diane.
"Three-Dimensional Neural Spheroid Culture: An In Vitro Model for Cortical Studies." Tissue Engineering Part C: Methods, vol. 21, no. 12, 2015, pp. 1274-1283.
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Dingle YT, Boutin ME, Chirila AM, Livi LL, Labriola NR, Jakubek LM, Morgan JR, Darling EM, Kauer JA, Hoffman-Kim D.
"Three-Dimensional Neural Spheroid Culture: An In Vitro Model for Cortical Studies." Tissue engineering. Part C, Methods, vol. 21, no. 12, 2015, pp. 1274-83.
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Toyjanova J, Hannen E, Bar-Kochba E, Darling EM, Henann DL, Franck C.
"3D Viscoelastic traction force microscopy." Soft Matter, vol. 10, no. 40, 2014, pp. 8095-106.
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Beane, Olivia S., Fonseca, Vera C., Darling, Eric M.
"Adipose-derived stem cells retain their regenerative potential after methotrexate treatment." Experimental Cell Research, 2014.
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Kanthilal, Manisha, Darling, Eric M.
"Characterization of Mechanical and Regenerative Properties of Human, Adipose Stromal Cells." Cellular and Molecular Bioengineering, 2014.
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Marble, Hetal D, Sutermaster, Bryan A, Kanthilal, Manisha, Fonseca, Vera C, Darling, Eric M.
"Gene expression-based enrichment of live cells from adipose tissue produces subpopulations with improved osteogenic potential." Stem Cell Res Ther, vol. 5, no. 5, 2014, pp. 145.
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Beane OS, Fonseca VC, Cooper LL, Koren G, Darling EM.
"Impact of aging on the regenerative properties of bone marrow-, muscle-, and adipose-derived mesenchymal stem/stromal cells." PLoS ONE, vol. 9, no. 12, 2014, pp. e115963.
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Desai HV, Voruganti IS, Jayasuriya C, Chen Q, Darling EM.
"Live-cell, temporal gene expression analysis of osteogenic differentiation in adipose-derived stem cells." Tissue engineering. Part A, vol. 20, no. 5-6, 2014, pp. 899-907.
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González-Cruz RD, Darling EM.
"Adipose-derived stem cell fate is predicted by cellular mechanical properties." Adipocyte, vol. 2, no. 2, 2013, pp. 87-91.
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Athanasiou KA, Darling EM, Duraine GD, Hu JC, Reddi AH.
Articular Cartilage. Taylor & Francis Group, LLC, 2013.
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Darling Eric M., Athanasiou Kyriacos A.
"Bioactive scaffold design for articular cartilage engineering." Biomedical Technology and Devices Handbook, 2nd Edition, edited by Moore Jr J, Maitland D, Boca Raton, FL, CRC Press, 2013.
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Desai HV, Voruganti IS, Jayasuriya C, Chen Q, Darling EM.
"Live-cell, temporal gene expression analysis of osteogenic differentiation in adipose-derived stem cells." Tissue engineering. Part A, vol. 19, no. 1-2, 2013, pp. 40-8.
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González-Cruz RD, Fonseca VC, Darling EM.
"Cellular mechanical properties reflect the differentiation potential of adipose-derived mesenchymal stem cells." Proceedings of the National Academy of Sciences, vol. 109, no. 24, 2012, pp. E1523-9.
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Beane OS, Darling EM.
"Isolation, characterization, and differentiation of stem cells for cartilage regeneration." Annals of Biomedical Engineering, vol. 40, no. 10, 2012, pp. 2079-97.
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Gilchrist CL, Darling EM, Chen J, Setton LA.
"Extracellular matrix ligand and stiffness modulate immature nucleus pulposus cell-cell interactions." PLoS ONE, vol. 6, no. 11, 2011, pp. e27170.
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Darling EM.
"Force scanning: a rapid, high-resolution approach for spatial mechanical property mapping." Nanotechnology, vol. 22, no. 17, 2011, pp. 175707.
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Yim EK, Darling EM, Kulangara K, Guilak F, Leong KW.
"Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells." Biomaterials, vol. 31, no. 6, 2010, pp. 1299-306.
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Darling EM, Wilusz RE, Bolognesi MP, Zauscher S, Guilak F.
"Spatial mapping of the biomechanical properties of the pericellular matrix of articular cartilage measured in situ via atomic force microscopy." Biophysical Journal, vol. 98, no. 12, 2010, pp. 2848-56.
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Athanasiou KA, Darling EM, Hu JCY.
Articular Cartilage Tissue Engineering. Morgan & Claypool Publishers, 2009.
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Darling EM, Pritchett PE, Evans BA, Superfine R, Zauscher S, Guilak F.
"Mechanical properties and gene expression of chondrocytes on micropatterned substrates following dedifferentiation in monolayer." Cellular and Molecular Bioengineering, vol. 2, no. 3, 2009, pp. 395-404.
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Darling EM, Guilak F.
"A neural network model for cell classification based on single-cell biomechanical properties." Tissue engineering. Part A, vol. 14, no. 9, 2008, pp. 1507-15.
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Coles JM, Blum JJ, Jay GD, Darling EM, Guilak F, Zauscher S.
"In situ friction measurement on murine cartilage by atomic force microscopy." Journal of Biomechanics, vol. 41, no. 3, 2008, pp. 541-8.
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Darling EM, Topel M, Zauscher S, Vail TP, Guilak F.
"Viscoelastic properties of human mesenchymally-derived stem cells and primary osteoblasts, chondrocytes, and adipocytes." Journal of Biomechanics, vol. 41, no. 2, 2008, pp. 454-64.
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Darling EM, Zauscher S, Block JA, Guilak F.
"A thin-layer model for viscoelastic, stress-relaxation testing of cells using atomic force microscopy: do cell properties reflect metastatic potential?." Biophysical Journal, vol. 92, no. 5, 2007, pp. 1784-91.
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Darling EM, Zauscher S, Guilak F.
"Viscoelastic properties of zonal articular chondrocytes measured by atomic force microscopy." Osteoarthritis and Cartilage, vol. 14, no. 6, 2006, pp. 571-9.
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Darling EM, Athanasiou KA.
"Growth factor impact on articular cartilage subpopulations." Cell and tissue research, vol. 322, no. 3, 2005, pp. 463-73.
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Darling EM, Athanasiou KA.
"Rapid phenotypic changes in passaged articular chondrocyte subpopulations." Journal of Orthopaedic Research, vol. 23, no. 2, 2005, pp. 425-32.
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Darling EM, Athanasiou KA.
"Retaining zonal chondrocyte phenotype by means of novel growth environments." Tissue engineering, vol. 11, no. 3-4, 2005, pp. 395-403.
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Darling EM, Athanasiou KA.
"Bioactive scaffold design for articular cartilage engineering." Biomedical Technology and Devices Handbook, edited by Moore J, Zouridakis G, Boca Raton, FL, CRC Press, 2004.
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Darling EM, Hu JC, Athanasiou KA.
"Zonal and topographical differences in articular cartilage gene expression." Journal of Orthopaedic Research, vol. 22, no. 6, 2004, pp. 1182-7.
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Darling EM, Athanasiou KA.
"Articular cartilage bioreactors and bioprocesses." Tissue engineering, vol. 9, no. 1, 2003, pp. 9-26.
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Darling EM, Athanasiou KA.
"Biomechanical strategies for articular cartilage regeneration." Annals of Biomedical Engineering, vol. 31, no. 9, 2003, pp. 1114-24.
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